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Joseph Andrew Bracken

Metaphysics for a World in Evolution
...rce and ongoing field of activity. The One can then be readily integrated into a hierarchical ordered system of fields within fields at all levels of existence and activity within nature. In the final part of the article, I indicate how this new field-oriented understanding of the relation between the One and the Many may help to solve controversial issues in natural science and Christian systematic theology.

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Muhammad Mushtaq

E-mail | mushtaq@uaar.edu.pk

... 25% reduction in burrow activity was achieved in case of groundnut – maize (1:1) grain bait loaded with 2% strychnine alkaloid and supplemented with 5% saccharin and a 10% reduction could be achieved without saccharin supplementation. In case of without pre-baiting trial, a 10% reduction in burrow activity was recorded in case of saccharin supplemented groundnut – maize grain bait impregnated with strychnine alk...

Asma Noshad1, Mudassar Iqbal1*, Zafar Iqbal1, Hamida Bibi2, Saifullah3, Salma Bibi4, Hamid Ullah Shah1

...valuate the insecticidal activity of the ethyl acetate extracts from fruit bodies, mycelia and fermentation filtrate obtained from Pleurotus ostreatus also known as the oyster mushroom. The percent mortality of Macrosiphum rosae (rose aphids) and the LC50 values were calculated and used as an indicative of insecticidal potential. The maximum mortality of aphids was achieved at 80 µg mL-1 and the LC50 for the fruit body ex...

Rabnawaz1*, Muhammad Jamal Khan2, Tahir Sarwar2, Mohammad Jamal Khan3

...ter than any other human activity. In Pakistan, the contribution of irrigated agriculture is more than 90%, thus the sustainable water supply to meet the food and fibre demand of the ever increasing population is a big challenge. Increase in crop water productivity (CWP) is one of the most important options for sustainable use of water resources in semi-arid environment. A field study was conducted during Rabi 2010-11 and Kharif 2011 crop s...

Youssef Lhor1*, Mounir Khayli1, Mohamed Bouslikhane2, Mehdi El Harrak3, Ouafaa Fassi Fihri2

Email: y.lhor@yahoo.fr

...dicator of the infecting activity of C. imicola. Collectively, the distribution patterns and emergence of BT can be predicted by the abundance of the Culicoides species in a specified locality so that control measures
can be implemented well in time to contain the disease spread.

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Tomas Jinnerot1*, Karin Malm1, Erik Eriksson1 and Jonas Johansson Wensman2

E-mail | Tomas.Jinnerot@sva.se

... which showed no cross-reactivity in silico or when tested with a panel of bacterial isolates. The limit of detection was determined to 4x103 bacteria per mL of nasal swab sample and less than 10 copies of target DNA per PCR reaction. Out of 23 isolates of B. bronchiseptica tested, one isolate from a hedgehog was not amplified. Sequencing of the 16S rDNA showed that the isolate was similar to strains of both B. ...

Mudasir Irfan Dar*, Fareed Ahmad Khan and Farha Rehman

E-mail | irfanmudasir@gmail.com

...The antioxidative enzyme activity of SOD, APX and GR showed increasing trend in a dose-dependent manner, attaining maximum at 40 g.a.i ha-1 of Imidacloprid treatment at day 7 after treatment (DAT) followed by 3 and 15 DAT, respectively. On the contrary, the CAT activity was increased at lower concentrations of Imida- cloprid but showed a dose dependence decline at higher concentrations of the insecticide at all the observed ...

Ali Mohammadi, Mohammad Hossein Ebrahimi

...mited degree of physical activity. However, most of young subjects are not recommended to be treated with this method owing to high level of physical activities. KineSpring knee implant system was designed for young subjects with knee OA to reduce knee pain, improve stability and knee function. The aim of this review article is to screen for the available information on knee implant system and to propose a suitable remedy for effective mana...

Murtaza Ali*, Yasser Durrani and Muhammad Ayub

...ensory parameters (water activity, ash content, percent acidity, pH, moisture content, reducing and non-reducing sugars, taste, texture, color and overall acceptability). Statistically minimum decrease was observed in water activity, pH, moisture content and organoleptic characters. While, stable increase was noted in percent acidity and ash content during storage. It was concluded and recommended on the basis of mentioned f...

Felwa A. Thagfan1, Mohamed A. Dkhil1,2* and Saleh Al-Quraishy1

...ed for its anticoccidial activity against Eimeria paillata induced infection in mice jejunum. Three different doses, 300, 600 and 900 mg/kg were used after infection of mice with sporulated oocysts. A dose of 300 mg/kg reduced the number of oocyst output in mice faeces by about 56.8 % and also improved the body weight. In addition, the root extract decreased the number of parasitic stages and the number of goblet cells in the jejunal villi in the infect...

Wan-Long Zhu* and Gao Wenrong 

...protein contents and COX activity both in liver and brown adipose tissue, suggesting that A. chevrieri was more sensitive to cold than that of photoperiod. Together, these data suggested that A. chevrieri mainly depend on increasing thermogenic capacity to cope with cold or winter condition.

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Paul I. Ankeli, Mashood A. Raji, Haruna M. Kazeem, Moses O. Odugbo, Nendir J. Umaru, Idowu O. Fagbamila, Livinus T. Ikpa, Obinna O. Nwankiti, Issa A. Muraina, Pam D. Luka and Nicholas D. Nwankpa

... They had no phosphatase activity, did not produce ‘film and spots’ and neither hydrolysed arginine nor urea and were preliminarily identified as members of the Mycoplasma mycoides sub-cluster which comprises Mmm and Mycoplasma mycoides subspecies capri (Mmc). Three (3) of the 8 Mycoplasma isolates were identified as Mmm using the IS1296F/R(all) and MM450/MM451 primer sets. The 574 bp product obtained by MM450/MM451 primer set gave two fragments (3...

Ai Ming Zhou1,2, Guang Wen Liang2, Ling Zeng2, Yong Yue Lu2 and Yi Juan Xu2*

...d the ghost ant foraging activity both on plants and the ground. Ant diversity in fire ant-infested plots was significantly reduced compared with in fire ant-free plots. Compared with in the no-ant plots, the colony growth rate of mealybug significantly increased, and the parasitism of mealybug was obviously decreased, both in fire ant-infested plots and in fire ant-free plots. Colony growth rate of mealybug in fire ant-infested plots was greater than fire ant...

Ayanda Opeyemi Isaac,1,* Oniye Sonnie Joshua2 and Auta Jehu2

 

... abnormalities like hyperactivity, abnormal swimming, restlessness, loss of equilibrum and haemorrhage. Observation of opercular ventilation count (OVC), tail fin movemant rate (TMR) and air gulping index (AGI) showed a marked difference between control and exposed fishes, indicating that the herbicides negatively impact on these parameters. These behavioural and morphological anomalies became more pronounced with increasing concentrations of the herbicides. M...

Ambreena Hafiz1, Tanzeela Riaz2 and Farah Rauf Shakoori1*

...nt of enhanced metabolic activity.

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Taghreed A. Hafiz1, Murad A. Mubaraki1*, Mohamed A. Dkhil2,3 and Saleh Al-Quraishy2

... DPPH radical scavenging activity and in the MTT assay the extract has relatively low cytotoxicity where the IC50 value of extract against Vero cells was 1078.69 µg/ml. Furthermore, the extract exhibited a considerable anti-HSV-1 and anti-HSV-2 activities at the concentration of 25 μg/ml. In conclusion, our findings indicate that the methanolic extract of Capsicum annuum could be used in combination with standard drug to treat herpes infection.

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John G. Bruno

... was significant cross-reactivity between the various captured serotypes, each of the anti-LPS aptamer candidates showed a preference for its cognate E. coli serotype. Results suggest that these aptamers may be useful for enriching specific E. coli pathogens during aptamer-magnetic separation in food samples, leading to a greater ability to detect these serotypes if coupled with genetic identification techniques such as PCR or gene probe hybridization.

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Dein Simon

...undamentalism Project: Reactivity, dualism, absolutism and inerrancy, apocalypticism. Additionally both underscore the role of evidentialism. From my analysis of these characteristics I conclude that the movement is fundamentalist

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Shazia Irfan1*, Asima Rani1, Muhammad Arshad2 and Razia Bashir1

...s still unknown. Reduced activity of antioxidants enzymes because of polymorphisms in antioxidant genes and variations in levels of metals and minerals creates oxidative stress may play some role in progression and pathogenesis of RA. The objective of this study was to investigate the role of Superoxide dismutase 1 (SOD1) gene polymorphism [rs2070424 (–251A/G)] in RA and to compare the levels of metals and minerals among its various genotypes in RA patie...

Iram Liaqat1*, Najma Arshad2, Muhammad Arshad3, Safdar Ali Mirza4, Nazish Mazhar Ali1 and Ammara Shoukat1

...ies level. Antimicrobial activity of aqueous and methanolic plant extracts of Camellia sinensis (Green tea), Syzygium aromaticum (Clove) and Mentha piperita (Peppermint) was evaluated against identified isolates. Agar well diffusion assay was used to monitor the antimicrobial activity of these strains both in mono culture and mixed culture. Streptomycin sulphate (10 μgml-1) and Amphotericin B (5 mgml-1) were used as posit...

Sana Irshad Khan1*, Zafar Iqbal2, Hamid Ullah Shah2 and Shaukat Hussain3

Rashid Mahmood1*, Saima Asad2, Ghulam Sarwar1, Waqar Ahmad1, Ziyad Abdul Qadir1, Ammara Balouch1 and Muhammad Khalid Rafique1
...er to study the foraging activity of honeybees in the field condition, the number of pollen foragers returning to the hive entrance was recorded for 10 min duration on hourly basis between 0800 h to 1600 h for 3 days per week. The data was collected at 0800–1000 hours (early morning foraging activity), 1000-1200 hours (late morning foraging activity), 1200-1400 hours (Noon foraging <...

Pam D Luka, Frank N Mwiine, Bitrus Yakubu, Joseph Erume, Ricardo Pérez-Sánchez, Hermann Unger and David Shamaki

...howed moderate to high reactivity, suggestive of domestic pigs’ exposure to tick-bite. Antibody reactivity’s were found in eight of the 10 states studied and all the states have favourable climatic conditions for soft ticks’ survival and national parks harbouring wild swine (warthogs) able to maintain the developmental cycle of these ticks. This provides some evidence of interaction between the host and the...
Fermín Lopez-Uriostegui1, Jesús T. Ponce-Palafox2,*, Fabiola Lango-Reynoso1, María del Refugio Castañeda-Chavez1, Virgilio Eugenio Arenas-Fuentes3 and Fernando Vega-Villasante4
...es feed 24 h, but forage activity differs in intensity in the two species. In M. tenellum repletion index was greatest during the day and M. americanum in the night.
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Mirza Imran Shahzad1,*, Anna Iqbal2, Farrah Ali1, Nuzhat Sial3, Muhammad Ashfaq4, Abul Hasanat5 and Azra Khanum6
Memoona Akber1, Muhammad Mushtaq1,*, Muhammad Sajid Nadeem1, Amjad Rashid Kayani1 and Noor-un-Nisa2 
...ter season. Reproductive activity revealed that the males were recorded reproductively active throughout the year while more than 50% specimens of females were recorded inactive throughout the year; yet lactating and pregnant females, and scars in the oviduct were recorded throughout the year indicating that Norway rat reproduces the year around in the urban environment of Rawalpindi, Pakistan.
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Muhammad Waqas1*, Anwar Ali Shad1, Omaira Bashir2 and Mohsin Iqbal3

...t (87.52 %). Antioxidant activity of carotenoids from tomato peel was assessed by measuring Rancimat’s test and diphenyl-1-picrylhydrazyl (DPPH) by using 50 to 200 mg/kg carotenoids in sunflower oil and spaghetti. The sunflower oil containing 50 to 200 mg/kg carotenoids showed higher antioxidant activity in comparison to 200 mg/kg Butylated hydroxytoluene (BHT). Optimum cooking time, its weight and swelling index were ...
Xiang Nong1,2,3,*, Yao-jun Yang1,2, Guang-you Yang3, Feng-zheng Chen2, Mei Tang1,2 and Gang Wang2
...i>. The insecticidal activity of stigmasterol was weaker than that of ageraphorone compound obtained from E. adenophorum Spreng. Through preliminary separation. However, in the experiments, we found an interesting phenomenon, that is, the dead state of mites treated with stigmasterol was similar to that of mites of the positive control group treated with fenvalerate. Furthermore, the dead state of mites treated with stigmasterol was different from t...
Ahmed Mujtaba1, Tariq Masud1, Asif Ahmad1, Waqar Ahmed3, Saqib Jabbar3* and Robert E. Levin2
...cluded the antibacterial activity of apricot (Prunus armeniaca L.) and its by-products. The aim of the study were to test the activity of chlorogenic acid isolated from apricot cv. Habi, against different food borne pathogens and quantification of the chlorogenic acid (CA) using High Performance Liquid Chromatography (HPLC). The chlorogenic acid was isolated using resin. The recovered amount of compound was calculated...

A. K. Chaubey and Satyandra Kumar

Bio-management of root knot nematode and root rot disease by antagonistic fungi and rhizobacteria
...Petri plates. Antifungal activity was tested by dual culture of wilt fungus with antagonist fungus and bacteria isolates in PDA media plates. In in-vivo test soil was amended with antagonist and wilt fungal and bacterial isolates 2 x 106 CFU/ml and 2 x 108 CFU/ml respectively as talc formulation @ 0.2% (w/w). Twenty one days old tomato seedlings were transplanted after dip treatment in antagonist fungal and bacterial CF in earthen pots filled with amended soil...

S. Subharani, S. S. Thorat, N. Abem, L. Amit Kumar and T. K. Singh 

A database on parasitoid of insect pests of crops in Manipur, India
... distribution, period of activity, parasitoid behavior and its biology etc. Image of the parasitoid species are also provided for helping in easy identification of the species. Keywords: Database, insect-pest, parasitoids, Manipur
 

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Madhuban Gopal, Rajesh Kumar and Arunava Goswami 

Nano-pesticides - A recent approach for pest control
...ealed many fold improved activity of nanopesticides against fungi and mites as compared to commercial sulphur.

 

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Goutam Mondal

Plant growth promoting activity of some indigenous Tricho-derma isolates and their field performance against sheath blight of rice in old alluvial zone of North Bengal
...gal and their biocontrol activity were tested in dual culture and found effective against soil-borne plant pathogens, namely, Fusarium oxysporum f. sp. ciceri (Padw.) Matuo. and Rhizoctonia solani Kühn. Efficacy in plant growth promoting activity of all the isolates was also tested on cauliflower (Brassica oleracea var botrytis L.), chilli (Capsicum frutescens L.) and tomato (Lycopersicon esculentum Mill.) with culture ...

A. Sajeena and T. Marimuthu

Efficacy, stability and persistence of Ganosol, a Ganoderma based fungicide against plant pathogens
...tability. The antifungal activity of the formulation persisted up to seven days after spraying the formulation on rice plants. The formulation retained its 100% antifungal efficacy up to three months of storage. Surprisingly, spraying cowpea plants with the formulation as simultaneous spray reduced the number of lesions produced by Groundnut Bud Necrosis virus in cowpea by 88.39% when compared to the inoculated control, suggesting the antiviral potential of th...
Zhensheng Liu1,2, Hui Gao1,2, Jiapeng Dong1, Mingming Zhang3 and Liwei Teng1,2,*
... We studied the seasonal activity of blue sheep from May 2010 through August 2012 to test the activity budget hypothesis, which predicts that females spend more time on feeding and that the activity synchronization of same-sex groups is higher than for mixed-sex groups. Our results support the hypothesis. Both males and females spent most of their time on feeding and moving. Feeding behavi...
Bushra Niaz1,*, Tahir Zahoor1, Muhammad Atif Randhawa1 and Amer Jamil2
...luation of antibacterial activity of lactoferrin. Minimum inhibitory concentration (MIC) of lactoferrin was determined by 96-well plate method using ELISA reader. Results depicted that CM-Sephadex C-25 was a good cation exchanger for recovery of lactoferrin. Camel raw milk produced 2.4 mg/mL of lactoferrin. The lactoferrin isolated from camel milk exhibited promising antibacterial activity against E. coli and Staph...

Furukh Faiz1,2, Muhammad Issa Khan2, Masood Sadiq2 and Haq Nawaz3

...f the broiler birds. The activity of the superoxide dismutase, catalase and glutathione peroxidase in the broiler blood was increased as the citrus waste level in the feed of the broilers was increased. The citrus waste addition in the feed of the broiler have non-significant effects on the growth parameters, however it has positive effects on the antioxidant enzymes profile of the broilers.

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Aneela Qureshi1, Ammara Ainee1*, Muhammad Nadeem1, Masooma Munir1,2*, Tahir Mahmood Qureshi1, Saqib Jabbar2
...ying fiber content water activity, texture, color, moisture, fat, protein, ash, NFE and fiber content changed significantly (p<0.05). Gross energy level in cake which is desirable by consumers was reduced but high fiber cake was dark colored, low in volume and with increased hardness. Treatment (T3) containing 5.6g grapefruit albedo powder shows significantly (p<0.05) higher sensory scores in term of color (8.02±0.50), flavor (8.04&plus...
Shuangye Wang1, Yunlin Zhao1, Zhenggang Xu1,2,*, Li Li3, Liang Wu1, Choucang Duan1 and Jiao Peng1

 

...d after 13:00 hours when activity behaviour increased. The adaptation of Milu was documented to a certain extent, it was found that the animal’s behavioural rhythms changed during acclimation to the new habitat. It is likely that resting and feeding behaviours were influenced by temperature.
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Saba Irshad1,*, Ayesha Ashfaq1, Ammara Muazzam1 and Abida Yasmeen2
...diarrheal and anticancer activity of turmeric (Curcuma longa L.) and black pepper (Piper nigrum L.), used in Pakistani cuisine to enrich flavour and to treat infectious wounds. Their crude ethanol and methanol extracts were tested against five important bacterial and fungal strains. Both extracts showed maximum antibacterial activity against B. subtilis, E. coli and S. aureus. All alcoholic...

Wali Khan1, Naushad Khan2 and Shaista Naz2*

...ngaged in the beekeeping activity. It also provided multiple sources of employment mainly in honey transportation and marketing, thus beekeeping not only served as an income generating activity but also an employment generating activity in present and in future. The major constraints in beekeeping were the expensive inputs, pest attack, lack of modern production and rearing techniques, and...
Muhammad Abdullah1,*, Rashid A. khan2, Muhammad Rafay3, Tanveer Hussain3, Tahira Ruby4,Fariha Rehman5, Sangam Khalil3 and Sohail Akhtar6
...osystem. To analyze this activity present work was planned to collect the preliminary information about habitat requirements and different breeding aspects of Cattle egret (Bubulcus ibis). The fieldwork was performed for two years (2012, 2013) at three different stations in the surrounding area of Faisalabad. Based on results it was concluded that Cattle egrets are colonial breeders and colonies were monospecific with no other ardeidae members nesting i...

Jawad Anwar* and Zafar Iqbal 

...tigate the antibacterial activity of Trichoderma harzianum against phyto and human pathogenic bacterial strains. T. harzianum was grown under different conditions and their extracts were evaluated, using disc diffusion method against tomato wilt causing bacteria (Xanthomonas campestris and Clavibacter michiganensis). Extracts that resulted in strong activity were fractionated into acetonitrile and ethyl acetate followed by t...
Furqan Sabir1, Muhammad Tayyab1,*, Bushra Muneer2, Abu Saeed Hashmi1, Ali Raza Awan1, Naeem Rashid3, Muhammad Wasim1 and Sehrish Firyal1
...>TN showed maximal activity at 80°C in 50 mM sodium acetate buffer pH 6. Presence of Fe3+ or Cu2+ showed an enhancing effect on the PHYTN activity. Thermostability studies demonstrated that PHYTN retains 88% residual activity when the protein was incubated at 80°C for 1.5 h in the presence of 1.5 mM Fe3+. The enzyme exhib...
Fang Wang, Yong-Fang Jia, Po Wang, Qi-Yan Du and Zhong-Jie Chang*

 

...rug that can inhibit the activity of cytochrome P450 aromatase, so as to affect the production of estrogen. In the present study, to detect the effects of letrozole on gonad differentiation, 5dph fry of carp were exposed to different concentrations of LET. At 130 dph, sex ratio was recorded. The results showed that continuous exposure to LET induced the changes of sex ratio. High concentration of LET can promote male-biased sex ratio. In order to reveal the mo...
Muhammad Usman Qamar1, 2, Sidrah Saleem1, Usman Arshad1, Muhammad Farhan Rasheed3, Hasan Ejaz4, Naveed Shahzad5 and Shah Jahan6,*
...itro anti- bacterial activity of Manuka honey against NDM-1 producing clinical isolates of Pakistan. A total of five carbapenem resistant bacterial species; E. coli, K. pneumoniae, E. cloacae, A. baumannii and P. aeruginosa, were isolated and identified using VITEK 2 compact system. Carbapenamase and metallo-β-lactamase (MBL) production by these isolates was confirmed by modified Hodge’s test and disc potentiation method, respectiv...
Rana Muhammad Aadil1,2*, Xin-An Zeng1, Saqib Jabbar3, Akmal Nazir2, Abid Aslam Mann2, Muhammad Kashif Iqbal Khan2, Abdullah2, Amna Ramzan2
...total anthocyanins, DPPH activity, total antioxidant capacity (TAC), total flavonoids (TF) and total flavonols as equated to thermal and control, while ºBrix, pH and acidity remain unchanged in all HPP treatments with control and thermal. After this, we suggested that HPP treatment (250 MPa/60 °C/3 min) has a potential against thermal to progress the value of grapefruit juice and could be applicable at industrial scales.
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Zahid Mehmood*, Alam Zeb and Muhammad Ayub 

...c compounds, antioxidant activity, ascorbic acid) and organoleptic characteristics (flavor, color, texture and overall acceptability). The results revealed decrease (P<0.05) in pH, ascorbic acid, total phenolic content, antioxidant activity while increase in acidity, total soluble solids during six months storage. Decrease in score of organoleptic attributes was recorded during the storage. The results revealed that (P<...
Ayesha Aihetasham1,*, Muhammad Saeed Akhtar1, Maryam Umer1, Khalid Zamir Rasib2 and Muhammad Imran Din3
Mahreen Yahya, Noor Abid Saeed*, Sajid Nadeem, Muhammad Hamed and Sajid Shokat 
...d reduced photosynthetic activity. Photosynthetic rate and chlorophyll contents were significantly higher in insecticide treated plots. Maximum cost-benefit ratio was found (1:9.2) in NW-1-8183-8 when treated against aphids. Wheat varieties, Galaxy-13 and Faisalabad-08 were found tolerant against aphid damage. Wheat variety Lasani-08 should be avoided because it was found susceptible to aphid infestations, and give low net yield. It is inferred that infestatio...

 Zeenat Bano1,*, Sajid Abdullah1, Waqas Ahmad2, Muhammad Anjum Zia3 and Wardah Hassan1

...so exhibited highest SOD activity in all the organs as compared to farm and hatchery fish. The activity of CAT enzyme was higher in kidneys and gills of farm fish compared to the liver of hatchery fish. The maximum POD activity was recorded in liver, kidney and gills of hatchery fish. This study reveals that fish could acquire higher uptake of metals due to excessive pollution of heavy met...
Carolina A. Bonin1,2, Eric A. Lewallen2,3, Andre J. van Wijnen3, Marta Jussara Cremer4 and Paulo C. Simões-Lopes5*
...ing as the most frequent activity in the estuary, totaling nearly two thirds of all records. We also identified two sites of Guiana dolphin habitat preference in our study area, where sightings remarkably totalled > 62% of observation records. These sites (especially Guaraqueçaba Bay) were not only important for feeding, but also for S. guianensis socialization. The detection of these key areas should facilitate both local and broad-scale effo...
Zhenyu Chang1, Hui Zhang1, Khalid Mehmood1,2, Mujeeb Ur Rehman1, Xiaodan Yuan1, Zhaoyang Li1, Fazul Nabi1, Xiaoxing Wu1, Xinxin Tian1, Xueting Liu1, Jingen Xu3 and Donghai Zhou1,*
...rvive and maintain their activity for several hours in tissue samples. For this study piglets without colostrum feeding were selected. Primary cell culture and subculture was performed from the intestinal epithelial cells of piglets. Then the effects of intestinal trefoil factor (TFF3) in intestinal disease was explored. Porcine intestinal epithelial cells were treated with lipopolysaccharide (LPS) and recombinant human (rh) TFF3. Cell proliferation and TFF3 m...
Amtul Jamil Sami1,*, Madeeha Khalid1, Rehman Shehzad1, Sana Mughal1 and A.R. Shakoori2 
...eks for growth promoting activity. Increased mammary growth was observed in test female non lactating mice, as compared to controls when placental lactogen was applied. Increase weight gain for visceral tissues like kidney, liver, muscle and lungs was also observed, as compared to control subjects. It was also recorded that the exogenous supply of bubaline PL reduces fat cells in the hypodermal layer of skin.
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Toshina Mushtaq, Muhammad Javed and Sidra Abbas*
... 30 days. The peroxidase activity was found to be significantly increased both in liver and kidney after ZnCl2 treatments. Statistically significant increase in the liver and kidney peroxidase activity of 96-h LC50 exposed fish were found as 0.621±0.004UmL-1 and 0.219±0.002UmL-1, respectively as compared to the control fish liver (0.123±0.002UmL-1) a...
Aqsa Imtiaz and Abdul Rehman*
...howed maximal keratinase activity at 37°C and at pH 8. An increase in keratinase activity of B. subtilis BML5 was determined in the presence of Ca2+, Mg2+, and Zn2+ while keratinase activity was inhibited by added copper ions. A 130-kDa protein was detected from feather-treated bacterial cells, suggesting its role in degrading feather. ...
Saleh S. Alhewairini
...ot affected with minimal activity in both applications compared with control. Moreover, no mortality of adults emerging from pupae was recorded and they only showed detectable reduction on their movement in both field treatments. Finally, this study would recommend the use of oxamyl in managing and controlling the infestation of RPW.
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Tariq Mahmood*1, Syed Wasif Ahmed Shah1, Muhammad Rais1, Hira Fatima1, Faraz Akrim1 and Muhammad Sajid Nadeem2
...e monitored for breeding activity of the particular bird species through clutch size, incubation period, and hatching success. Sixty-two active nests of various bird species were recorded; common myna Acredotheris tristis, house crow Corvus splendens, Indian robin Saxicoloides fulicatus and black drongo Dicrurus macrocerus preferred Kikar Acacia nilotica and Eucalyptus camaldulensis for nesting purpose while black kite...
Sidra Iqbal1, Muhammad Irfan2*, Hafiz Abdullah Shakir1, Fouzia Tabbsum1, Javed Iqbal Qazi1
... FPase (2.526 IU/ml/min) activity was found at pretreatment conditions of 0.6% NaOH conc., 10% biomass loading and 4h reaction time while CMCase (2.803 IU/ml/min) at 1% NaOH conc., 15% biomass loading and 6h of reaction time. The proposed model was found highly significant as revealed by their F-values, P-values and R2 values. Results suggest the efficiency of Bacillus subtilis K-18 for cellulase production from eucalyptus leaves and it would be fruitful for f...

Fatima Arshad1, Muhammad Irfan2*, Hafiz Abdullah Shakir3, Fouzia Tabbsum3, Javed Iqbal Qazi3
 

...ment. The maximum CMCase activity was 1.757 1U/ml/min under conditions of 0.6% acid concentration, 10% substrate concentration, and resident time of 4h. The maximum FPase activity was 2.015 1U/ml/min under conditions of 0.8% acid concentration, 10% substrate concentration, and time of 6h. This showed that peanut shells could successfully be used as substrate for cellulase production in submerged fermentation.

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 Asma Akhtar, Abdul Rehman

...te dehydrogenase (G6PDH) activity was increased to 279% (1f) and 150% (2b) when ompared to the respective control indicating the ability to tolerate tellurite tress. Differential pattern of bacterial proteins in tellurite stress was obtained by SDS-PAGE. Both bacterial strains can be utilized to convert toxic tellurite into its elemental form from the contaminated sites.

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Rimsha Nawaz1, Muhammad Javed1, Sidra Abbas1* and Safina Kousar2
...ide on peroxidase enzyme activity in the fish, Labeo rohita. For this purpose, four groups of Labeo rohita (one-year old) were exposed to different treatments as 96-h LC50, 2/3rd, 1/4th and 1/5th of LC50 concentrations of iron chloride for 30 days in the glass aquaria with three replications for each treatment. After 30-day exposure of iron chloride, the fish organs viz. kidney and liv...
Faiza Hassan1, Mubshara Saadia1,*, Muhammad Sher1, Mian Anjum Murtaza2, Muhammad Arshad3,Asam Riaz4 and Mahmood Ahmad Khan5
...p<0.001) hypoglycemic activity with no considerable effect on mean body weight of rats (ns, p>0.05) as compared to diabetic rats. The AGE treatment has significantly reduced the blood glucose level (56%), however, the EGE treatment was found effective in normalizing the lipid contents of diabetic rats. The black cumin oil treatment has resulted in significant (p<0.001) increase (48%) in body weight of diabetic rats, but found less active in regulating...

Farah Rauf Shakoori, Momina Shokat, Faiza Saleem and Tanzeela Riaz

...enzyme possessed maximum activity. Two bacterial isolates XPB-GS02 and XPB-CW01 with maximum activity ratio showed 18.3 and 12.2 U/ml xylanase activity, respectively. Maximum xylanase was produced in medium M1 containing xylan after 48 hours of incubation. Maximum amount of enzyme was produced by XPB-GS02 at 45ᵒC, pH 9 using 1% xylan concentration, while XPB-CW01 produced maximum amo...
Tasleem Akhtar*, Muhammad Asif Aziz, Muhammad Naeem, Muhammad Sheraz Ahmedand Imran Bodlah
...orsata (0.98%). Peak activity of the insect visitors was observed at the mid of the day i.e., 12:00 pm. The activity of managed A. mellifera started to increase from the third week of blooming (20th Jan, 2015) and reached to maximum in the sixth week (10thFeb, 2015). Among the abiotic environmental factors, temperature had a strong, significant and positive correlation with the foragin...
Alim-un-Nisa1*, Sajila Hina1, Sania Mazhar1, Imran Kalim1, Ijaz Ahmad1, Naseem Zahra1, Shahid Masood1, Muhammad Khalid Saeed1, Qurat-ul-Ain Syed1 and Maida Asif2
...her it has antibacterial activity. The lethal dose and toxicity determination of the color extracted from marigold showed that it is safe for consumption as no clinical symptoms were observed in rabbits after giving the maximum dose of 1000ml of color.
...
Muhammad Naeem1, Bushra Sadia1,2,*, Faisal Saeed Awan1and Muhammad Anjum Zia3
..., EB 11, EB 13 with hyperactivity as compared to wild bacterial strain. Out of the total 15 isolates of EtBr-treated strains, EB4 gave the maximum enzyme activity (7.3 ± 0.005 U ml-1) with a zone diameter of 6 mm. While UV6 was found to be the best UV-induced mutant with an enzyme activity of 20.333 ± 0.006A U ml-1 and 16 mm of zone diameter. ...

 Muhammad Asim, Muhammad Asif, Muhammad Munir* and Muhammad Aslam**

...ODI-3 retained more radioactivity as compared to Williams-82 in inoculated as well as uninoculated plants. The stem and roots of Williams-82 plants had a percent distribution of ABA that was higher than NODI-3. The phloem sap of Williams-82 had higher accumulation of 3H-ABA at all stages after treatment. The basal levels of ABA in phloem sap were lower in NODI- 3 than in Williams-82. Inoculation further accentuated this difference. The major changes in ABA lev...

 Rahila Nazli, Tehmina Sohail, Bushra Nawab and Zahra Yaqeen*

...tigate its antimicrobial activity against gram +ve and gram-ve bacteria. The study was also extended to some species of fungi. Results showed that the activity was more pronounced against gram +ve organisms and fungi. Maximum inhibition activity was calculated against all the groups of organisms, which was between 0.5 and 1mg ml-1 against bacteria and 2.5 mg ml-1 against fungi. It is there...
Promy Virk
...aluate the anti-diabetic activity of the prepared nanopcomposite. Antidiabetic potential of orally administered bulk aqueous extract of Trigonella (TBE) and Au/Ag nanocomposite with Trigonella seed extract (TN) on streptozotocin (70 mg/kg) induced diabetic rats was assessed for a period of 7 weeks. Metformin was used as a standard drug. The results of Zetasizer and Transmission and Scanning Electron Microscopy images showed the presence of spheri...
Abul Hassan Faiz*, Fakhar-i-Abbas and Lariab Zahra Faiz
...effects of rat burrowing activity on, plant biomass, saturation, pH, electrical conductivity, organic matter, potassium and phosphorous concentration. These significant differences in soil composition have long-term effects on ecosystem sustainability and productivity of vegetation.
...
Amtul Jamil Sami1,*, Sehrish Bilal1, Madeeha Khalid1, Muhammad Tahir Nazir1 and A.R. Shakoori2

 

...ct of saponins. The AChE activity of T. castaneum was inhibited by the saponins and follows competitive inhibition kinetics. In case of A. mellifera enzyme activity was not inhibited. In vitro and in vivo inhibition was observed for T. castaneum at larval stages, in dose dependent and time dependent manner. LC50 was determined to be 0.7ppm. To investigate the different effects of sap...
Nazish Shaukat1, Muhammad Javed1,Faiza Ambreen2* and Fariha Latif1
...ct of lead on peroxidase activity (antioxidant enzyme) in the gills and liver of Labeo rohita. Experiment was conducted in the laboratory by exposing four groups of Labeo rohita to different doses of PbCl2 viz. 96-h, 2/3rd, 1/4th and 1/5th of LC50, separately, for 30 days and compared with control group. After 30 days, fish was sacrificed and their gills and liver isolated to determine...

Akhlaq Ahmad, M. Anwar Arain*, Rahila Nazli**, Syed Anser Rizvi***,
Mubarik Ahmed* and Farzana Ibrahim****

Corresponding author: dr.akhlaqahmad@yahoo.com

COST EFFECTIVENESS OF UNDER-SHEET AND WHOLE GODOWN FUMIGATION OF BAGGED WHEAT
...showed no sign of insect activity during the 8 months storage. From the study, it is concluded that under-sheet fumigation of stacks of bagged wheat is a very cost effective and feasible method for protection of stored cereals, and need to be implemented at the provincial and national levels.

 

...

 Ambreen Akhtar Saddozai, Saeeda Raza* and Shahzad Arshad Saleem**

MICROBIAL COUNT AND SHELF LIFE OF STRAWBERRY JUICE
...uence of microbiological activity on different quality factors of strawberry juice during storage. Strawberry was purchased from local market and its juice was kept for two weeks at room temperature to check its shelf life. Total plate count (TPC), pH, flavor, color, yeast and moulds were checked weekly. Quality changes of strawberry juice during storage can be caused both by microbiological and physiological processes. At day 0; pH 3.2, color bright 2 -1 red,...

 Abid Hussain*, Khalid Mahmood Aujla* and Sonila Hassan**

ECONOMICS OF COW MILK PRODUCTION IN SINDH AND AZAD JAMMU & KASHMIR
...on is profitable farming activity in irrigated areas of Sindh and mountainous-AJK with benefit-cost ratios of 1.5 and 1.4, respectively. While, benefit-cost ratios of cow milk production were 1.0 and 0.7 in desert and coastal areas of Sindh, respectively, indicating subsistence nature of cow farming in these ecologies.

...

 Muhammad Sharif*, Muhammad Azam Niazi* and Abdul Jabbar**

SEAFOOD EXPORTS: CHALLENGES AND WAY FORWARD
... most important economic activity along the coastline of provinces of Sindh and Balochistan. This paper assesses current stock of seafood production, seafood exports, direction and future prospects of seafood exports from Pakistan. The production of inland and marine fish was 729,000 t in 2012-13. Not only seafood output in the country is low but dwindling to the disastrous level. Export of seafood has increased from 131,620 t (a value of US$ 315.5 million) in...

 Mazher Abbas*, Irfan Mehmood*, Arshed Bashir*, Muhammad Ather Mehmood* and Sonila Hassan* 

WOMEN COTTON PICKERS PERCEPTIONS ABOUT HEALTH HAZARDS DUE TO PESTICIDE USE IN IRRIGATED PUNJAB
...marily a female specific activity in all cropping zones of Pakistan. Women cotton pickers mostly belong to poor rural society involved in this labour force to feed their families. Cotton pickers in Pakistan face some serious health related problems due to heavy use of pesticides on cotton crop. The present study was designed to investigate the problem faced by women cotton pickers and their role in household decision making. Overall 150 women cotton pickers we...

 Muhammad Zahid Kiani*, Arshad Ali**, Tariq Sultan** and Muhammad Munir Ahmed***

CHARACTERIZATION OF PLANT GROWTH PROMOTING RHIZOBACTERIA ISOLATED FROM ROOT SYSTEM OF SUNFLOWER (HELIANTHUS ANNUS L) GROWN UNDER SALT AFFECTED AREA OF PAKISTAN
...owed maximum bio-control activity (fungal growth inhibition) than other isolated strains.

...

 Riaz Hussain*, Muhammad Riaz**, Mushtaq A. Saleem*** and Muhammad Ishaque Mastoi**

BIOCHEMICAL ABNORMALITIES INDUCED BY ABAMECTIN IN SIXTH INSTAR LARVAE OF THE RED FLOUR BEETLE, TRIBOLIUM CASTANEUM (HERBST)
...AK strain larvae, the TE activity was inhibited with depletion of total protein contents and elevation of FAA contents. In FSS-II larvae, the effect of abamectin on levels of α-amylase, glucoamylase, AkP, total protein and soluble protein remained non-significant. The activities of TE and AcP were reduced at both doses, while activities/levels of CE reduced at LC and FAA increased 10 at LC . It is concluded that abamectin affected the overall body 20 fun...

Muhammad Hidayat Rasool*, Abuzar Muhammad Afzal*, Abu Baker Siddique*, Waseem Akram**, Muhammad Saqalein*, Madiha Basit* and Muhammad Farooq Tahir***

ANTIVIRAL ACTIVITY OF VIRO CARE GZ-08 AGAINST NEWCASTLE DISEASE VIRUS IN POULTRY AND ITS IN-VITRO CYTOTOXICITY ASSAY
...his study, the antiviral activity of Viro Care GZ-08™ was checked up invitro, in-ovo and in-vivo. The cytotoxicity assay of the product was performed using Vero cell line. All the trials revealed that the stock solution and 1:2 dilution of GZ-08™ had some antiviral activity as well as were cytotoxic. As the concentration decreased, cytotoxicity as well as antiviral activities were lost. Based on these findings, i...

 Sameera Arshad*, Iftikhar Hussain*, Maqsood Anwar* and Sarwat Naz Mirza*

HABITAT SURVEY FOR RECOGNIZING BIRD ATTRACTANTS AROUND BENAZIR BHUTTO INTERNATIONAL AIRPORT, ISLAMABAD, PAKISTAN
...ighly conducive for bird activity which in return is a serious safety concern for aircraft operation. Outcome of this study could be incorporated into off airfield bird management programme for monitoring bird activity and land use practices around the airfield.

...

 Ambreen Akhtar Saddozai*, Amer Mumtaz*, Saeeda Raza* and Shahzada Arshad Saleem** 

MICROBIAL COUNT AND SHELF LIFE OF PHALSA (GREWIA ASIATICA) JUICE
...ill two weeks. Microbial activity in phalsa juice increased while organoleptic attributes such as texture (mouth feel), flavour, taste, colour and overall acceptability of phalsa juice were decreased during the study period. The pH and TSS value were decreased from 3.99 to 3.54 and from 11.22 to 9.55, respectively after 2 weeks -1 -1 storage. Total plate count also showed decline from 6.2×10 to 3.2 x 10 -1 cfuml whereas yeast and mould counts increased s...

Sumia Bint Zaman*, Waqas Farooq*, Sidra Majeed*, Hasnain Shah*, and Abdul Majid**

ASSESSMENT OF AGRICULTURE SERVICE PROVIDERS' TRAINING ON WATER CONSERVATION TECHNOLOGIES IN POTHWAR REGION
... included as part of the activity. The information for paper is collected from opinions of the participants before and after the training. Descriptive analysis alongwith paired 't' test was used to measure the effectiveness of training. Results indicated higher satisfactory level as majority of the participants were strongly agreed (73%) and agreed (23%) that trainings were participatory and skill development oriented and as 96% agreed or strongly agreed that ...

 Tasawar Sultana*, Farah Deeba* and S.M. Saqlan Naqvi*

HIGH-THROUGHPUT AGROBACTERIUM-MEDIATED TRANSFORMATION OF MEDICAGO TRUNCATULA IN COMPARISON TO TWO EXPRESSION VECTORS
...peroxide dismutase (SOD) activity in transformed progeny. 

...
Anum Rafique, Sajid Abdullah, Khalid Abbas, Huma Naz* and Wardah Hassan
...treated fish had highest activity as 508.33 and 427 UmL-1 while highest specific activity was 1105.06 and 1055.55 Umg-1 with 1.98 and 2.70 fold purification, respectively. Recovery was 70% and 68% in kidney of control and Pb+Cr treated fish, respectively. After characterization it was observed that SOD had wide range of pH i.e. 4.0-8.5 and maximum activity of 5...
Rabia Faiz and Dilara A. Bukhari*
...rmining the insecticidal activity of cyt positive B.t. strains against 3rd instar larvae of mosquito. Larval mortality was noted after 24 h and GCU B.t. 4 (400± 1.15) was found to be the most toxic against 3rd instar larvae of mosquitoes. Spores LC50 values of other isolates were 451± 0.90 (GCU B.t. 1), 511± 0.85 (GCU B.t. 2), 525± .013 (GCU B.t. 5), 582&plus...
 Nazia Qamar1, Sher Khan Panhwar1,* and Ralf Riedel2,*
... showed a higher feeding activity. The IRI showed fish, followed by crustaceans, to be the most important food item for S. commersonnianus and S. tol. This study is to offer baseline data toward implementing a fishery in Pakistan for current and future generations.
...
Zhiping Hu, Hussain Ahmad, Jingfei Zhang, Lili Zhang and Tian Wang*
...thione peroxidase enzyme activity was significantly increased in T1 group compared to CON group at 42d. Malondialdehyde content of liver in T1 group was lower than that of CON group. These results suggested that dietary supplementation of 10 mg/kg natamycin had a positive influence in broilers.
...
Chuanpeng Zhou1, Heizhao Lin2,*, Zhong Huang2, Jun Wang1, Yun Wang1 and Wei Yu2
... hepatic pyruvate kinase activity peaked 6 h after oral administration in both doses of glucose groups and thereafter started to decrease 24 h after oral administration. While the hepatic PEPCK and G6Pase activities decreased 9 h after oral administration in both doses of glucose groups and then returned to the level at 0 h (P<0.05). These results suggested that glucose oral administration resulted in prolonged hyperglycemia and high level of hepatic...
Sabah Mansoor1, Muhammad Tayyab1,*, Amna Jawad1, Bushra Munir2, Sehrish Firyal1, Ali Raza Awan1, Naeem Rashid3 and Muhammad Wasim1
...enzyme exhibited optimum activity at 55 °C between pH 8-9. The effect of metal ions on the activity of AMYSBS showed that Co2+ remarkably enhanced the enzyme activity and 500µM was recorded as optimal Co2+ concentration for the maximal activity of AMYSBS. Presence of ionic (SDS) and nonionic (Tween-20...
Shahzad Mahmood1, Memuna Ghafoor Shahid1, Muhammad Irfan2, Muhammad Nadeem3*, Quratulain Syed3
...C and attained 96% activity at 40oC for 70min. Metal profile showed that α-amylase activity was enhanced in the presence of Ca2+, Cs1+, Mn2+ and Co2+, whereas inhibited in the presence of Na1+, Mg2+, Ag1+ and Cu2+. Enzyme kinetics revealed that crude enzyme exhibit Km and Vmax of ...
Muhammad Shahbaz Aslam1, Iram Gull1, Zaigham Abbas2,* and Muhammad Amin Athar1
...nation of its biological activity. SUMO-IFNα2-Tα1 was successfully expressed in soluble form with IPTG induction to final concentration 0.5 mM at 37oC for 4 h and purified using affinity chromatography. SUMO tag was removed from SUMO-IFNα2-Tα1 by SUMO protease and recombinant IFNα2-Tα1 was collected in flow through by affinity chromatography. The MW (~23 kDa) of IFNα2-Tα1 was determined by 12 % SDS-PAG...
Ayesha Munir, Hafiz Muhammad Umer, Anjum Nasim Sabri and Imran Sajid*
...nsible for antimicrobial activity and biofilm dispersion. Overall the results indicated that natural extracts from these Streptomyces strains and their active components can be exploited for the preparation of anti-caries products like mouth washes and tooth pastes etc.
...
Hongqun Li1, Xiaoli Liu2,*, Zhenmin Lian3,RenheWang4, Yongbin Wang4, Yongyao Fu1 andDingyi Wang5
...st that moderate logging activity and prohibition of local peoples’ firewood collection in the core areas may provide some optimal nest habitat for the brown-eared pheasant.
...
Huma Naz1,*, Sajid Abdullah2, Sidra Naz3, Sidra Abbas2, Wardah Hassan2, Shakeela Perveen2, Moazama Batool1, Laiba Shafique2
...ral changes and catalase activity in liver, kidney, gills, brain and muscle of the fish were also studied. The mean 96 h LC50 and lethal value for C. mrigala was determined as 47.56±0.04 and 93.89±0.07 mgL-1, respectively. The selected concentration of Fe+Ni+Pb+Zn concentrations showed strong and direct relationship with, fin movement followed by mucous secretion, hyperactivity and ...
Farah Rauf Shakoori1,*, Anum Feroz1, Ayesha Gondal1,Sahar Akram2 and Tanzeela Riaz3
...nificantly reduced while activity of trehalase were significantly increased after treatment with sub lethal dose of λ-cyhalothrin as compared to control. The metabolic derangements induced by sub-lethal dose of λ-cyhalothrin suggest that infestation caused by T. granarium in godowns could be overcome by calculating lethal dose of λ-cyhalothrin.
...

Nashwa Mohamed Eid1, Al-Hussien Mohamed Dahshan1, El-Shayma El-Nahass2, Basma Shalaby3 and Ahmed Ali1* 

...d better anticlostridial activity in terms of reduced CP counts in intestine and alleviation of intestinal damage caused by infection. In conclusion, the EOs are effective feed additives to treat and/or prevent NE in poultry. Further studies on the effect of EOs on other enteric infection, intestinal microbiota, poultry feed components, and poultry meat quality are required. 

...
Fazul Nabi1,2, Hui Zhang1, Muhammad Kashif Iqbal1 , Mujeeb ur Rehman1, Muhammad Shahzad3, Khalid Mehmood1,3 and Jiakui Li1,* 
...kaline phosphatase (ALP) activity and increase in alanine aminotransferase (ALT) and aspartate aminotransferase (AST) activities in the serum along with decrease in level of antioxidant enzymes and significantly increase in the MDA contents in TD afflicted chickens compared to control group. The SM administration to TD affected birds significantly ameliorated lameness, stimulated ALP level with a decrease in ALT and AST contents, increase in antioxidant parame...
Abdur Rahman1,*, Ibrahim Sadi Cetingul2, Ismail Bayram2, Cangir Uyarlar2, Abdil Burhaneddin Akkaya2, Eyup Eren Gultepe2, Hikmet Keles3, Aykut Ulucan4 and Zafar Hayat1
...s may have the potential activity to modify the gut morphology and can result in better performance of the quail by increasing the nutrient absorption from the intestine.
...
Souheila Slimani1,*, Sonia Hamouda1, Chahrazed Souadi1, Sara Silini2, Cherif Abdennour2 and Leila Delimi3
...ng photoperiodthe sexual activity of the control lasted only 04 weeks, characterized by significant increase in the testicular volume, followed by spontaneous gonadal regressionup to week 10. Consequently, an azospermia and lack of germ cells in control birds was noticed,which confirm the testicular regression.In the treated groups, thiram delayed the refractory phase along the experimental period, but testicular weight were superior in the treated pigeons com...
Nina Bao1,*, Yongguang Yin2 and Panpan Wang3
...rebroside. Meanwhile, bioactivity showed that the extraction has antibacterial activity, and the purified one is better than the crude one.
...
Changqing Zhao*, Zhuochi Chen and Yubin Li
...jerky; the acid protease activity was slightly higher than the neutral protease activity in the fermented jerky; four and fifteen volatile compounds were detected for the non-fermented and fermented jerky, respectively. The important compounds affecting the flavor of fermented jerky included DL-Glutamic Acid, Phenylethyl Alcohol, 1-Octen-3-ol, Nonanal, Pentanal, 3-Methyl-Butanal, and 2-Pentyl-Furan. The study results demonst...
Yang Yang1,2, Yun Liu1, Mingxu Zhou1 and Guoqiang Zhu1,*
...> caused decreased QS-II activity.
...
Sukirno Sukirno1,2, Muhammad Tufail1,3,*, Khawaja Ghulam Rasool1Said El Salamouny1, 4, Koko Dwi Sutanto1 and Abdulrahman Saad Aldawood1
...op pests, however, their activity is deteriorated rapidly when exposed to the sunlight. Many UV protectants were used to improve the efficacy of these viruses under field conditions. The objective of the current study was to evaluate the effectiveness of plant extracts to improve the persistence of Spodoptera littoralis multiple nucleopolyhedrovirus (SpliMNPV) against beet army worm, Spodoptera exigua(Hübner) under harsh sunny field c...
Amna Waseem, Sikander Ali* and Syeda Wajiha Khalid
...7 showing maximum lipase activity of 71±3.55 U/g, was selected. Resistance in the hyper producing strain was developed by exposing it with low levels of L-cysteine HCl to protect it from instability. It was observed that under optimum conditions at 30°C temperature, pH 7, and incubation period 64 h, the lipase activity was increased up to 124±2.48 U/g. The crude enzyme was purified by ammonium sulfate preci...
Sahar Naz1, Farhan Rasheed2, Muhammad Saeed3*, Shagufta Iram4 and Ambereen Anwar Imran5
Safia Rehman1, Nazish Mazhar Ali1,*, Gerald B. Pier2, Iram Liaqat1 and Bushra Mazhar1
...to enhance antimicrobial activity against these pathogens.
...
Adem Aksoy1, Yakup Erdal Ertürk2, Selim ErdoÄŸan3, Ecevit Eyduran3 andMohammad Masood Tariq4,*
...erformed only beekeeping activity. The four most influential predictors in the MARS were age of enterprise (100%), number of full beehives (100%), other races (97%), and other works except for beekeeping (90%). The best performance order was MARS (r=0.920) > CART (r=0.619) > multiple linear regression (r=0.286), which indicated that MARS outperformed other approaches. MARS reflected that the main and interaction effects of socioeconomic (age of enterpris...

Muhammad Zahid1, Naeem Iqbal1, Sohaib Muhammad2*, Summiya Faisal3, Wajid Mahboob3, Makhdoom Hussain4 and Zaheer ud din Khan2 

...rates. Nitrate reductase activity and total soluble proteins were increased with increase in sugar treatments under drought. Osmotic and water potentials were reduced under drought but foliar glucose sprays of 10 mM and 50 mM applied at reproductive phase significantly reversed the adverse effects of drought. Gas exchange characteristics including CO2 concentration, transpiration and photosynthesis rates were raised by glucose treatments under irrigated and no...
Kiran Aqil1, Muti-ur-Rehman Khan2, Asim Aslam2, Aqeel Javeed5, Rizwan Qayyum1, Farooq Yousaf,1 Farkhanda Yasmeen1, Muhammad Luqman Sohail3 and Sajid Umar4,*
...current study, antiviral activity of six dilutions of Nigella sativa (N. sativa)alcoholic extracts against the PPRV was investigated in vitro. Vero cell lines infected with PPRV were treated with six dilutions alcoholic extracts of N. sativa (200, 100, 50, 25, 12.5 and 6.25 µg/mL). The antiviral effects were judged by 3-(4,5)-dimethylthiahiazo (-z-y1)-3,5-di-phenytetrazoliumromide colorimetric (MTT) assay. Plaque reduction assay was ...

Qaisar Jamal1,Salman Ahmad1, Nazma Habib Khan1, Sobia Wahid1, Muhammad Ikram2, Sadia Rehman2, Syed Basit Rasheed1 and Akram Shah1,* 

...gate in-vitro anticancer activity of two transition metal compounds of derived Schiff bases; NM-3 (Tetrakis (2-{(E)-[(2- {[(Z)-(2-hydroxynapthyl) methylidene]amino} phenyl)imino] methyl}phenol) Copper(II) and NM-4 (Tetrakis (2-{(E)-[(2- {[(Z)-(2-hydroxynapthyl) methylidene] amino}phenyl)imino]methyl} phenol) zinc(II)), against human THP-1 leukemia cell line in-relation to miltefosine (standard chemotherapy). Mean % inhibition for NM-3 against THP-1 was higher ...
Iqbal Ahmad Alvi, Muhammad Asif, Rabia Tabassum, Zaigham Abbas and Shafiq ur Rehman*
...ge with no fall of phage activity.
...
Faxiang Wang, Yan Chen, Sai Chen, Xianghong Li, Jian Yu, Jianhui Wang and Yongle Liu*
...e Ca2+-ATPase activity of protein decreased gradually during the storage period. The high MW proteins easily degraded during the cold storage, and the proteins with low MW were relatively stable but still gradually degraded. So the key time point for cold storage of grass carp is approximately 4-6 days.
...

Sana Rana1, Sajid Abdullah1, Huma Naz2* and Khalid Abbas1 

...ixture on catalase (CAT) activity in gills of carnivorous fish Channa striata was observed. Fish were exposed to sub-lethal concentration (1/3rd of LC50) of DM+END mixture for 14-day. CAT was partially purified by using ammonium sulphate precipitation technique and kinetic characterization was also performed against different pH and temperature. CAT activity was measured spectrophotometrically at A240 nm. Results showed that...
Soumble Zulfiqar1, Khuram Shehzad1, Sana Tahir1, Khalid A. Al-Ghanim2 and Abdul Rauf Shakoori1,2,3,*
...shown to possess laccase activity. In this study, we have cloned and over-expressed the CueO of locally isolated Klebsiella pneumoniae KW strain. The CueO protein was purified to homogeneity by nickel affinity chromatography. Enzyme assays of CueO protein with phenolic substrates revealed its laccase activity. The kinetic studies showed Km value of 0.2µM, kKcat 0.68 S-1 and Kcat/km 1.2S-1
Nimra Naseer, Adeela Fatima and Imran Sajid*
...ignificant antimicrobial activity against MDR bacterial pathogens. Secondary metabolite profiling of each methanolic extract by TLC and HPLC-UV signified the presence of unique and diverse metabolic compounds. The study predicts that the seactinomycetes strains are a potential resource to cope up with evolving multi drug resistant pathogens. Furthermore, these secondary metabolites can be identified by comparative studies and these actinomycetes can be grown o...

Zulqarnain and Zafar Iqbal* 

... their potent antifungal activity against the Fusarium wilt of tomato. Six distinct fungal species including Penicillium sp., Aspergillus niger, Aspergillus flavus, Trichoderma harzianum, Alternaria solani and Pythium aphanidermatum showed growth inhibition (%) against the pathogen. Penicillium sp. showed maximum growth inhibition (63.85 ± 3.26 %) and its extract showed 9.20 ± 0.14 mm zone of inhibition at 1000 mg·L-1 against the Fusarium ...
Song Jiang1,2, Fa-lin Zhou1, Qi-bin Yang1, Jian-hua Huang1, Li-shi Yang1 and Shi-gui Jiang1*
...peroxide dismutase (SOD) activity, glutathione (GSH) and adenosine triphosphate (ATP) concentration, as well as nitric oxide synthase (NOS) activity and nitric oxide (NO) concentration catalyzed by NOS. Based on biochemical analysis of the above, results showed that O2- production could be induced significantly after cold stress at 15°C and heat stress above 30°C. SOD ac...
Mehwish Aftab, Tariq Mahmud*, Muhammad Asim Raza Basra, Aqsa Gulzar, Sumaira Basharat and H.M. Junaid
... base showed antioxidant activity against diphenylpicrylhydrazyl (DPPH). The results showed that metal complexes are good antioxidant agents as compared to Trolox (standard) and ligand was less active as compared to Trolox. The Schiff base ligand and its metal (III) complexes showed antibacterial activity against E. coli, S. aureus by disc diffusion method and antifungal activity ag...
Ashraf M. Mounir, A.N. El shahat* and A.M. Abdul Azeem
...ammatory and antioxidant activity. Gamma-irradiation is used for decontamination of Boswellia tears to achieve satisfactory microbiological quality and public health safety. Hence, examining the effect of gamma-irradiation on the contents of Boswellia oleo-gum resin and also investigating the role of gamma-irradiate frankincense aqueous extract (GFAE) against ISO-induced MI in rats were the two aims of this study. The total phenolic content and t...
Farah Mansha, Abdul Rehman*
...es showed highest enzyme activity at pH 7. Isolates H4 and M4 showed maximum enzyme activity at 55°C while H1 showed highest activity at 70°C. Chitinase activities exhibited by H1 and M4 are stimulated by the presence of Zn2+ ions, while the presence of Ni2+,Cd2+ and Cu2+ did not show any positive effect. However in H4, presence of Zn&sup...

Asma Sohail1*, Aina Rafique2, Kashif Sarfraz Abbasi1 and Maryum Arif3 

... potential antimicrobial activity. Effect of drying methods (sun-, oven- and freeze drying) on antioxidant and antimicrobial activities of date fruit powders from three varieties Zahidi, Aseel and Muzafati were investigated. The DPPH activity was significantly higher in Muzafati sundried date powder, whereas maximum phenolic and flavonoid contents were significantly higher in Muzafati freeze dried date powders. Results sugge...

Asma Sohail1*, Kashif Sarfraz Abbasi1, Maryum Arif2 and Fatima Najam1 

... reduce their biological activity on heating, volatilization, and other parameters like oxidation and UV rays. This limits the commercial application of these oils. To overcome such problems encapsulation could be a gentle approach. Prior to encapsulation, oil extraction was done by using five different solvents including ethyl acetate, n-hexane, methanol, diethyl ether and chloroform in which ethyl acetate yielded 53% oil. Pumpkin seed oil was encapsulated us...
Muhammad Khan
...its potential anticancer activity. This review will mainly focus on the anticancer activity, cellular targets and anticancer mechanism of PSD-A which may help the further design and conduct of research and repositioning it for oncological clinic.
...

Nadia Khan1*, Abdul Waheed1, Farrukh Siyar Hamid1, Naveed Ahmed1, Zafar Iqbal2, Seemab Ali1, Madiha Bashir1 and Hina Gul3  

...d in vitro antibacterial activity against two phytopathogenic bacterial species (Clavibacter sp. and Xanthomonas sp.) and a human pathogenic bacterium (Escherichia coli) in 2016. Experiment was carried out by using complete randomized design with three replications in vitro. Phytochemical analysis reveals that the methanolic fraction of oil possesses metabolites like carbohydrates, amino acids, alkaloids, flavonoids and glycosides. To test the antibacterial
Tünay KontaÅŸ AÅŸkar1,*, Åžinasi AÅŸkar1, Olga Büyükleblebici2 and Murat Güzel3
...or myeloperoxidase (MPO) activity in CVL. Therefore investigation of this enzyme activity in dogs with leishmaniasis may be used for the diagnosis and inflammatory changes in dogs with VL.
...

Hareem Mohsin, Azka Asif*, Warda Fatima, Sarooj Nadeem, Anjum Nasim Sabri

Assessment of biocalcification by the water absorption test using microorganism from oil contaminated site
...nditions produced by the activity of the enzyme urease allowed the reaction between calcium and carbonate ions that leads to the precipitation of the calcium carbonate. The water absorption test was performed to check the presence of a protective layer that provides resistance to water penetration and corrosion to cement. The samples treated with calcium and urea for one hour were found better as shown by less absorption of water compared with the untreated s...

 Muhammad Mohsin Ahsan1, Hafiz Muhammad Tahir2, Muhammad Khalid Mukhtar1

Effect of lunar cycle on active population density of scorpions, their potential prey and predators
...f the lunar cycle on the activity of O. odonturus. Young (Immature)
individuals of all scorpion species were always high in numbers at night, even under moonlight conditions. The
activity of scorpion prey had been always high during dark nights. No difference in numbers of scorpion predators
(shrews, lizards, centipedes, mice and rats) was noted in the presence or absence of moonlight, but they were

 Mirfa Murtaza1, Sajid Abdullah1, Wardah Hassan1*, Khalid Abbas1, Huma Naz1, Muhammad Anjum Zia2

Studies on amylase and lipase activity in fishes fed with diet containing different feed ingredients
...ign: justify;"> The activity of digestive enzymes was determined in Hypophthalmichthys molitrix, Catla catla and Cyprinus carpio fed
with different feed ingredients. There were two glass aquaria (3×2×2 ft) for each species and ten fish in each
aquarium. Fish in one aquarium were fed on rice polish and fish in second aquarium were fed on corn gluten @ 3 %
of their wet biomass for 70 days. Results showed that fish wet weight...

Muddasir Hassan Abbasi1, 2, Noor Fatima1, Syed Shahid Imran Bukhari1, Asma Rashid khan3, Nadeem Sheikh2*

Variations in proteins and transaminases following experimental induction of Bisphenol A in mice
...n and aminotransaminases activity. The sodium dodecyl sulphate
polyacrylamide gel electrophoresis (SDS-PAGE) was also run to analyze protein bands. Statistically significant
increase in total protein contents, albumin and aminotransaminases were noted in sample in comparison with control.
Comparative analysis between experimental and control samples revealed protein fractions (KDa) of 149, 132, 101,
72, 75 and (163, 114, 91, 75, 72,...

Dilara Abbas Bukhari1, Abdul Rehman2*

Isolation of bioactive compounds from exudate of edible fungus, Pleurotus ostreatus
...hecked for antimicrobial activity against bacterial strain, Bacillus subtilus. Biochemical techniques, thin layer chromatography, high performance liquid chromatography and gas chromatography/mass spectrometry, were employed to study fungal exudate. A total of fifteen different metabolites were detected in the sample by GC/MS. The detected metabolites could be classified into chemical groups of 2 esters, 4 alcohols, 3 benzoic acids, ketone, aldehyde, phenyl an...

 Haniya Mazhar1, Naaz Abbas2, Zahid Hussain3, Amir Sohail4, Syed Shahid Ali4*

Extracellular lipase production from Bacillus subtilis using agro-industrial waste and fruit peels
...tion. The maximum enzyme activity (34.93 U/ml) was shown by B. subtilis using SSF with soya bean meal. The lipase production by other low cost agro-industrial waste, including sunflower meal, wheat bran, oat bran, rice bran and sugar cane bagasse was 23.83, 12.17, 10.40 10.00 and 16.23 U/ml, respectively. The lipase production by B. subtilis using peels of different fruits, including banana, orange, water melon and melon as carbon source, was 27.17, 21.37, 10....

 Muhammad Babar Khawar1, Muddasir Hassan Abbasi1, 2, Sana Fatima3, Khawaja Abdul Mujeeb2, Nadeem Sheikh1

Alterations in proteins and transaminases activity induced by thioacetamide in albino rats
... and serum transaminases activity after 12 and 24h of TAA administration in albino
rats. Rats were randomly divided into three groups (n=3) namely control group, 12h group and 24h group. Each
experimental group (12h and 24h) was administered 300 mg/ kg TAA intraperitoneally (i.p) while control received
same volume of normal saline solution. Rats of 12h and 24h group were killed after 12 and 24h of TAA administration
respectively. Bl...

 Mohsin Arshad1, Muhammad Irfan*2, Asad-Ur-Rehman1, Muhammad Nadeem3, Zile Huma3, Hafiz Abdullah Shakir4, Quratulain Syed3

Optimization of medium and substrate for CMCase production by Bacillus subtilis-BS06 in submerged fermentation and its applications in saccharification
...ve maximum
CMCase activity (8.0 ± 0.32 IU) after 48h of fermentation period at 37oC with
agitation speed of 140 rpm by using medium components III (M-III) and also
medium M-IV. The highest enzyme production was observed in the following order;
sugarcane bagasse > wheat straw > rice husk, wheat bran > soybean meal >
corncobs. The crude CMCase enzyme was applied for saccharification of
agricultural was...
Haniya Mazhar1, Naaz Abbas2, Tehseen Zamir3, Zahid Hussain1, Syed Shahid Ali4*
...ons and lipolytic enzyme activity shown by the bacterial isolate (PCSIR NL-37) from the soil of Lahore (Punjab, Pakistan) are being reported. Lipolytic bacterial strains (100) isolated from soil and water samples from oil industry, mobile oil filling areas and kitchen wastages were screened on tributyrin agar and rhodamine agar plates. The strain PCSIR NL-37 was identified as Bacillus cereus following morphological, biochemical and molecular characteriz...
Muhammad S. Waqas, Ali A.Z. Shoaib, Xinlai Cheng, Qianqian Zhang, Asem S.S. Elabasy and Zu-hua Shi*
... during the time of male activity, may be an effective practice for the management of this pest.
...
A.M. Abdul Azeem, A.N. El Shahat* and Ashraf M. Mounir
...c content andantioxidant activity of pomegranate peel powder as well as to evaluate the effect of gamma-irradiated pomegranate peels extract (GPE) against biochemical alterations of lead induced testicular and hepato-toxicity in rats. From the results, it was obtained that gamma irradiation induced significant increase in the total phenolic content and antioxidant activity of pomegranate peels powder. Concurrent treatments o...

Akshay Sharma*, Mohit Mahajan, Madhumeet Singh and Pravesh Kumar 

...scularity and functional activity of corpus luteum present on the left ovary. Ultrasonography was employed at weekly interval to judge the viability of embryo (up to 42 days), fetus (after 42 days) and late embryonic mortality, if any. Sexing of the twins was done on 56th and 70th day post artificial insemination and two male twins were confirmed on the basis of genital tubercle, median raphe, scrotal and penis impression. With the aid of ultrasonography and c...
Fatih Korkmaz1, Veysel Parlak2, Özgür Kaynar3, Arzu Ucar2, Gonca Alak1,* and Muhammed Atamanalp2
...ease in bacterial growth activity, physicochemical values (TVB-N, TBARS and pH) and prolonged shelf life in a natural preservative dependence were observed in the fillets. Generally all the test parameters, such as microbiological, physicochemical as well as the lowest mean values were identified in the coatings of the fillets with turmeric and cardamom (p<0.05). Control and quinoa groups resulted in increased number of bacteria and chemical values compared...
Jair Millán-Orozco1,*, Jersson Millán-Orozco2 and Luz María Tejada-Ugarte3
...i>P<0.05) grazing activity was observed during September (38.9±11.4 min/h), while in May (27.1±14.3 min/h) was the month with least activity (P<0.05). Within days, the highest (P<0.05) grazing activity was observed at 06:00, 12:00 and 18:00 h (34.9±12.0, 31.8±12.9 and 34.5±10.6 min/h, respectively), while 09:00 and 15:00 h (28.6...
Aqeel Mehboob, Syed Muhammad Zaka*, Muhammad Sarmadand Maryam Bajwa
...as oviposition deterrent activity against the S. litura was found when the above mentioned botanicals were tested.
...
Hao Gu*, Zhi Yang, Weiqiang Yu, Kan Xu and Yuan-fei Fu*
...xplore the antibacterial activity against the four cariogenic bacteria in terms of acid producing and biofilm. The antibacterial activity of capsaicin was evaluated by the minimal bactericidal concentration, change of pH in the first 12 h and OD values of biofilms. Besides, fluorescent images of exopolysaccharides and living bacteria of Streptococcus mutans were measured with confocal laser scanning microscopy (CLSM)....
Zhi YiJin1, Shao MingQin1,*, Cui Peng2 and Chen Bin1
...w time was budgeted, and activity rhythms were established in wintering Mandarin Ducks (Aix galericulata). This was done using instantaneous scan sampling in the Poyang Lake watershed in the Jiangxi province, China. The results showed that the Mandarin Ducks’ predominant behaviors were resting (36.56%), swimming (21.75%), foraging (20.88%), and maintenance (15.58%), indicating that during the winter, Mandarin Ducks spend most of their time accumul...

 Saira Zaheer1, Abrar Hussain1*, Aqsa Khalil1, Muhammad Mansha1, Muhammad Lateef2

...method. The anthelmintic activity was analyzed by adult motility assay (AMA). Levamisole was used as positive control to compare the efficacy of CEE of both plants. Adult worms were treated with different concentrations i.e., 2, 4, 6 and 8 mg/ml of ethanolic extract and motility of the worms was examined after every two to eight hours. Both A. lebbeck and C. sinensis exhibited 88% and 95% mortality at 6 & 8 mg/ml after 8 hrs of treatme...

Ummad-ud-Din Umar1, Syed Burhan-ud-Din2, Muhammad Fahad Khan1, Ateeq ur Rehman1, Syed Atif Hasan Naqvi1*, Muhammad Asif Zulfiqar3, Azhar Ali Khan3 and Naila Ilyas1

...dants. Highest enzymatic activity was observed in treated plants followed by inoculation with MYMV. Increase in resistance by the application of SA and BTH, antioxidant enzymatic activities of SOD, POD, CAT were also increased for second week. This revealed that SA and BTH can be used as a potential source for the activation of resistance for better management of MYMV by improving protection level by the induction of systemic acquired resistance. 

...
Fariha Latif* and Muhammad Javed
...red in terms of catalase activity in the gills, liver, kidney, muscles and brain. Among the fish species, C. mrigala accumulated significantly higher concentration of all metals as compared to L. rohita and C. catla. Bioaccumulation of all metals among the organs followed the order: liver>gills>kidney>brain>muscles, however, metals followed the trend for their accumulation: Cd>Cr>Cu>Pb. Antioxidant (catalase)
Muhammad Usman Ahmadand Ikram-ul-Haq*
...st oxyrase producer with activity of 0.41±0.008U/mL/min with 41% reduction in dissolved oxygen at pH 7.5, temperature 37°C, 25mM lactate as H+ donor after 20 min. This strain was later on confirmed by 16S ribotyping procedure. Oxyrase was used for improved cultivation of anaerobic bacteria by employing Hungate Technique where its antioxidant potential was compared with common reducing agent Cysteine-HCl (Cys-HCl). Four anaerobic bacterial...
Umar Farooq Gohar1, Hamid Mukhtar1,*, Ali Nawaz1, Ikram-ul-Haq1 and Asad Mehmmood2
...mg/ml. The antimicrobial activity was assessed by disc diffusion method. Cephalosporin production was estimated by using spectrophotometric technique.
...
Aisha Khalid1, Muhammad Tayyab1,*, Abdual Rauf Shakoori2, Abu Saeed Hashmi1, Tahir Yaqub3, Ali Raza Awan1, Muhammad Wasim1, Sehrish Firyal1, Zaheer Hussain4 and Munir Ahmad5
...rated the optimal enzyme activity at 90°C and pH 4.8. The presence of cobalt enhanced the cellulase activity and 2.5 mM cobalt was recorded the optimal concentration for the maximal cellulase activity. SDS-PAGE analysis confirmed the molecular weight of recombinant protein as 39 kDa. The protein was found thermostable which retained more than 70% residual
Iqra Bano1,*, Moolchand Malhi2, Pershotam Khatri3, Saeed Ahmed Soomro2, Hira Sajjad4, Ambreen Leghari5, Muhammad Awais2, Safia Kandhro6 and Shakeel Ahmed Lakho5 and Munaza Soomro7
...athione peroxidase (GPx) activity as well the testicular GPx activity was significantly increased in SY as compared to C. Furthermore, the serum T-SOD activity was significantly elevated in SY as compared to C. Moreover, the T-SOD activity in testicular tissues was also significantly increased in SY as compared to C. The results revealed that the SY supp...
Tahira Moeen Khan* and Amat ul Mateen
...ignificant antibacterial activity against four bacterial strains three gram negative (Escherichia coli, Proteus mirabilis, Salmonella) and one gram positive (Clostridium tetani). The minimum concentration of leaf extracts needed against these bacterial strains were also calculated. The present study indicated that Melia azedarach and Morus nigra leaf extracts can be used successfully for nanoparticles synthesis and CuO as significan...

 Huma Naz1,*, Sajid Abdullah2, Khalid Abbas2 and Muhammad Anjum Zia3

...r purification, specific activity of enzyme was 1750.13 and 1272.72 U mg-1 in kidney of metal exposed and control fish, respectively. The enzyme from metal exposed kidney was 2.68 fold purified with 58.73 % age recovery. Results of characterization showed that SOD had broad range of pH from 4 to 8.5 but show maximum activity at pH 7 and 7.5 for stressed and control fish, respectively. At 30°C
Jie Yang
...r bacteria. Bactericidal activity of human PGLYRP-1, PGLYRP-3, PGLYRP-4, and PGLYRP-3:4 for both Gram-positive and Gram-negative bacteria require Zn2+. In addition, for killing of Gram-negative bacteria, Zn2+ cannot be replaced by other cations, but for killing of Gram-positive bacteria, Zn2+ can be partially replaced by Ca2+, which have been proved. Then, the effect of human PGLYRP1 on several human diseases (inflam...
Muhammad Shahid Nadeem*, Maryam A. Al-Ghamdi and Jalaluddin Azam Khan
...However, the glutaminase activity of enzyme can cause serious side-effects triggering a search for highly specific and more stable enzyme. In the present study the gene consisting of 972bp coding for 323 amino acids was PCR amplified from Geobacillus thermodenitrificans DSM-465 was PCR amplified and recombinant plasmid pET22b-Asn was prepared. L-asparaginase was produced in BL21 (DE3) RIL codon plus strain of E. coli as heterologous protein under...
Muhammad Nasir1,*, Ata-ul-Mohsan2, Munir Ahmad2, Shafqat Saeed3, Muhammad Asif Aziz2, Muhammad Imran4 and Umer Ayyaz Aslam Sheikh4
...estris during flight activity period and solitary phase of development. Results showed that survival rate and colony initiation rate of the queen was highest at 28 ºC and 30 ºC. Different parameters in the initial stage of colony growth like pre-oviposition period and emergence timing of the first worker were observed best at 28 and 30 ºC. Number of workers produced in the first brood and in the total lifespan of the colony was also observed...
Huma Naz1,*, Sajid Abdullah2, Khalid Abbas2, Wardah Hassan3, Moazama Batool4, Shakeela Perveen5, Sadia Maalik4 and Sajida Mushtaq4
...fos) investigated on the activity of antioxidant enzymes viz. superoxide dismutase, peroxidase, catalase and glutathione S-transferase in different organs (liver, gills, kidney, brain, heart and muscle) of fish, Labeo rohita. The LC50 of chlorpyrifos+endosulfan mixture was calculated as 1.95±0.02 μgL-1 for 96 h with the 95% confidence limits. The fish expose to the mixture (1:1) for 96-h. The results obtained from this st...
Fan Yi1,2, Xiaobin Yang1, Shigen Ye1, Hua Li1 and Ruijun Li1,*
...es count, serum lysozyme activity, phagocytic rate, phagocytic index, respiratory burst activity of head kidney cells, compared with the basal feed group (P<0.05 or P<0.01). The challenge test results also showed that the 0.5% and 1% HCT feeding had higher immune protection against Edwarsiella tarda infection; and the relative protection ratios were 60% and 50%, respectively. It was also obtained t...
Aisha Khalid1, Muhammad Tayyab1,*, Abu Saeed Hashmi1, Tahir Yaqub2, Ali Raza Awan1, Muhammad Wasim1, Shagufta Saeed1, Sehrish Firyal1 and Abdul Rauf Shakoori3
...ein. Higher level enzyme activity was recorded at 25°C, pH 7.0 when the cells were induced with 0.5 mM IPTG with 22h post induction incubation. Supplementation of LB medium with 1% glucose and yeast extract enhanced the production of recombinant thermostable cellulase. Enzyme showed strong potential for its use in paper and poultry feed industry. Under the optimal conditions we could able to produce 48 U/mL of recombinant cellulase.
...

Javed Asghar Tariq1*, Bashir Ahmed2, Manzoor Ali Abro2, Muhammad Ismail1, Muhammad Usman Asif1 and Raza Muhammad1 

...d for their antagonistic activity against Fusarium oxysporum f.sp. alium cepa. They all were found to inhibit fungus showing inhibition zone 4.09 -74.97%. Hence, on the basis of these studies, it can be concluded that these bacteria can be used as a biocontrol agent to manage other fungal diseases of agricultural crops also. 

...
Zahra Nazir1, Saba Ijaz1, Roquyya Gul2 and Mahjabeen Saleem1,*
...rified polygalacturonase activity was found to be 4.5 and stable within pH range 3.5-5.5. Temperature dependent studies revealed temperature optimum of enzyme to be 40°C and stable up to 60°C. Among substrates, polygalacturonic acid was established as the best substrate for polygalacturonase showing its specificity in the hydrolysis of polysaccharide galacturonate chain. The presence of Na+1 and K+1 enhanced polygalacturonase
Rıfat Ertekin1*, Mete Ozkurt1, Gokhan Kus2 and Selda Kabadere1
...o PCR results, caspase-9 activity increased incrementally in groups given 50 μM of TA. The increase in the apoptosis of LNCaP cells may be due to the rising amount of TA concentration. In our study, in 25, 50, and 100 μM TA groups, cyclooxygenase-2 (COX-2) decreased incrementally compared to the control group. Considering overstimulation of COX-2 paths in emergence of cancer or in metastasis, this study shows TA has an antiproliferative and stimulating e...
Ailing Huang, Lingyu Meng, Wei Zhang, Junyan Liu, Guangyao Li, Huihua Tan, Wen Lu and Xialin Zheng*
...n other four pesticides; activity of glutathione-s transferase (GST) was inhibited by abamectin, while the trend was in the opposite direction for other four pesticides; activity of superoxide dismutase (SOD) was promoted by beta-cypermethrin and chlorpyrifos, and inhibited by abamectin and bisultap; Activity of catalase (CAT) was promoted by beta-cypermethrin, chlorpyrifos and bisultap, i...
Yuyu Wang, Gangchun Xu*, Zhijuan Nie, Quanjie Li, Nailin Shao and Pao Xu*
...eters, digestive enzymes activity and antioxidant status of largemouth bass (Micropterus salmoides) reared in an in-pond raceway system (IPRS). Fish (initial average body weight: 35.68±2.12g) were randomly allotted to in-pond raceways (26.2m×5m×2.5m) stocked at two stocking densities (68 and 114 fish/m3, respectively). Fish were fed twice daily (08:00 and 17:00), and the daily ration feed was 4% of the body weight. No signi...
Wang Zaigui1,*, Guo Panpan1, Ye Miao1, Sun Linghong1, Zhang Hongfu2 and Liu Chaoliang1,*
...coon quality and amylase activity of silkworm, Bombyx L, we got the following results: (1) In the larval duration of 3rd instar silkworm, average weight gain (AWG) and feed conversion ratio (RFC) were not significantly affected with the use of B. subtilis, but the remaining amount of mulberry leaves (RAML) was significantly decreased contrasting to the blank group (P<0.05). (2) In the larval duration of 4th instar si...
Iqra Jaffar, Zainab Sehzadi, Muhammad Adeel, Khalid P. Lone and Mehwish Faheem*
...r and gills by analyzing activity of glutathione-S-transferase (GST), catalase (CAT), glutathione (GSH) and by measuring lipid peroxidation (LPO). Catalase activity increased significantly in liver and gills of fish exposed to 10μg/l of DBP. Level of GSH and LPO increased significantly in gills while a non-significant decrease was recorded for GSH and GST in liver. These results showed that exposure to low concentrations ...
Rabia Khalid1, Saleema Bashir Shams1, Bibi Nazia Murtaza1,*, Gaitee Joshua1, Saira Mushtaq1, Hassan Al-Talhi2 and Abdulaziz Al-Amri2
...Associations of physical activity and sedentary behaviors with the tendencies of metabolic syndrome were evaluated. The experimental and laboratory values for BMI, total cholesterol (TC), total triglycerides (TG), high density lipoproteins (HDL), low density lipoproteins (LDL) and fasting blood glucose (FBG) were used to demonstrate the incidence of metabolic syndrome. Overall, 39.025% of bank employees and 22.53% of randomly selected control individuals have ...
Xiaohui Yu, Shuai He, Liqiang Wang, Mengyang Kang, Yanjiao Zhu, Shuhui Wang and Xiuzhu Sun*
... motility, mitochondrial activity, membrane integrity and arosome integrity. The results illustrated that compared with controls, above-mentioned indices of sperm were significantly improved under concentrations of Vitamin C (400 mg/L) and Vitamin E (600 mg/L) (P < 0.05). Moreover, physiological indices of donkey semen were significantly higher than the control groups (P < 0.05) when Vitamin C (200 mg/L) and Vitamin E (200 mg/L) were presen...
Wafaa M. Hikal1,2,* and Hussein A.H. Said-Al Ahl3
...l cysts. The amoebicidal activity of T. ammi oil was determined in vitro. Out of T. ammi oil showed that, higher concentrations (90 μg/mL after 72 and 96 hrs and 100 μg/mL after 24 and 48 h) was more active, being able to kill 100% of the Acanthamoeba cysts.The results showed the cysticidal activity of T. ammi essential oil, LC50 values estimated to be 73.31, 61.69, ...
Fatima Tufail1, Sajid Abdullah1, Huma Naz2*, Khalid Abbas1, Laiba Shafique3
...n hepatic catalase (CAT) activity of fish, Channa striata exposed to the sub-lethal concentration (1/3rd of LC50) for 14 days. The CAT was partially purified by using ammonium sulphate precipitation technique. Results of partial purification demonstrated that the exposure of insecticides mixture decreased the hepatic CAT activity in fish (43.33±1.41 UmL-1) as compare to control ...
Muhammad Naveed Sheas1, Haris Rasool2, Muhammad Nouman Rafique2, Muhammad Rizwan Tariq1*, Abid Muhammad1, Khubaib Ali1
...od swings, aversion from activity and apathy which affects the thoughts, behavior and feelings of wellbeing. Honey and curcumin, traditional folk medicines, are thought to steadfast the defense mechanisms of body against oxidative stress which is a key factor in elevating depression. This study is designed to reveal the efficacy of honey and curcumin against depression in rat model. 24 male wister rats were randomly divided into 4 groups. After the trial, bloo...
Xuefeng Cao1, Guangneng Peng1, Xiaobin Gu1, Changliang He1, Guizhou Yue2, Jun Shi3,* and Zhijun Zhong1,*
...and it showed no cross-reactivity with other pathogens. Sensitivity testing showed the minimum detection limits of real-time (RT)-PCR were 7.44×101 copies·μL-1 (CPV) and 4.20×101 copies·μL-1 (CDV). DARPM detection of CPV with DNA showed a minimum detectable of 1.53×101copies μL-1, while the minimum detectable amount from the virus culture supernatant was 6.70×...

Yasir Ali1,2*, Bashir Ahmad1, Naqeebullah Jogezai3 and Adil Hussain

...roteolytic and lipolytic activity with skim milk and Tributyrin agar (TBA plate) assay method. From the collected samples, a total of 20 bacterial isolates (PAK-01 to PAK-20) were exhibiting psychrotrophic physiology. About 8 isolates were capable of proteolysis in alkaline range of pH; and 6 bacteria exhibited lipolysis. Based upon primary and secondary qualitative screening, One isolate (PAK-01) exhibited maximum proteolysis on 1 % skim milk while another is...
Syed Makhdoom Hussain1*, Nisar Ahmad1, Azhar Rasul1, Muhammad Mudassar Shahzad2, Muhammad Latif3, Muhammad Zubair Ul Hassan Arsalan1, Muhammad Umair1  and Hafiza Hina Shafqat1
...g absorbance and surface activity, so the aim of research was to estimate the impact of Cr nanoparticles on growth performance, nutrient digestibility and hematological parameters of C. catla fingerlings fed nano- Cr particles supplemented sunflower meal based diets. The experiment was consisted on seven test diets on the basis of supplementation of nano Cr graded levels (0, 0.5, 1, 1.5, 2, 2.5 and 3 mg Kg-1). Chromic oxide was used as an ine...
Khansa Nazir1,*, Tariq Mukhtar1 and Humayun Javed2
...t study, the nematicidal activity of silver nanoparticles (AgNP) was investigated against the most destructive root-knot nematode (Meloidogyne incognita). The maximum mortality of juveniles was recorded at a concentration of 100 mg/ml followed by 75 mg/ml of AgNP. The minimum mortality was recorded with 25 mg/ml of AgNP. With the increase in concentration, there was a corresponding increase in the mortality of juveniles showing a direct relationship bet...
Muhammad Waheed Mushtaq1,*, Muhammad Waqar Younas2, Jamil Anwar2, Syed Mustansar Abbas3 and Shahid Bashir3
...ted enzymes, the working activity of separated enzymes was checked by performing desizing test for alpha-amylase and biopolishing test for cellulase. The noteworthy results of desizing and biopolishing test has promoted the significance of unidirectional freezing technique (UFT).
...
Emre Barlas1 and Elif Yamaç2,*
...ion of cave entrance and activity of cave values were determined. Seven out of 10 recorded bat species were evaluated as new records for the area. There was a significant preference for caves which were situated at lower altitude, far from paved road and close to water source. Bats were mostly found in longer caves. Caves with entrance oriented to northwest and southeast were preferred by bats. Undertaking effective conservation measures to maintain especially...

Azeem Haider1, Muhammad Mohsin Alam2*, Azhar Ali Khan3 and Muhammad Asif Zulfiqar3

...aximum level of xylanase activity (9.29 Uml-1), CMCase (7.37 Uml-1), laccase (13.57 Uml-1) and effluent decolorization (69.68 %) were observed on 7th day during shake flask studies.

...
Xiaopeng Tang1,2, Rejun Fang3,4,*, Guochang Pan1,2 and Kangning Xiong1,2,*
...tate dehydrogenase (LDH) activity of isolated small intestine at time on 0 min, 30 min, 60 min, 90 min and 120 min, to provide a appropriate operation time for Ussing chamber test. Then, a total of 20 Loman laying hens with similar weight (1.25±0.13 kg) were divided into 1 of 5 treatments: i) control group (0 ng/mL EGF), ii) 50 ng/mL EGF group, iii) 100 ng/mL EGF group, iv) 150 ng/mL EGF group, and v) 200 ng/mL EGF group for using chamber test. The...
Nouf Alharbi*, Mai Elobeid and Promy Virk
...peroxide dismutase (SOD) activity in liver, malondialdehyde (MDA) levels in liver and serum, and histopathological evaluation of liver and kidney. Results showed that low dose of quercetin was significantly (p≤0.05) more effective than the high dose. Low dose was more efficacious in reducing Cd accumulation in the tissues, reversing the effects of Cd toxicity on blood profile, and on the CAT and SOD activity in the liver ...

Muhammad Arshad1, Muhammad Irfan Ullah1*, Muhammad Afzal1, Mian Anjum Murtaza2, Ejaz Ahraf3, Zahoor Hussain4, Syed Muhammad Ali Zahid1 and Maryam Riaz1 

...ltivars caused by mining activity of CLM during summer 2016. The total leaf area and mine area per leaf were calculated by the image analysis method using Sigma Scan Pro 5.0 software. The results of the present study showed that CLM generated larger mines; 1.64 cm2 on Grapefruit, 1.44 cm2 on Kinnow and 1.40 cm2 on Succari compared to other five cultivars. However, the percent leaf damage due to the feeding of CLM larvae was observed higher 44.2% on Fairchild, ...
Gul Afshan1,2,*, Soumble Zulfiqar2, Sumaira Mehboob2, Muhammad Tahir Javed Khan1 and Abdul Rauf Shakoori2,*
...as significant antigenic activity and can potentially be used as recombinant vaccines against HCV infection.
...
Maliha Ayub1, Muhammad Javed1, Fariha Latif 1*, Faiza Ambreen2, Komal Sabir1
...manganese on antioxidant activity in the fish, Labeo rohita. Fish were acclimatized for two weeks in the cemented tanks prior to the start of experiment. Four groups (n=10) of one year old fingerlings of Labeo rohita were exposed to 96-hr LC50 and sub-lethal concentrations (2/3rd,1/4th and 1/5th of LC50) of manganese for a duration of 30 days in the glass aquaria of 70L water capacity. After ...
Zijuan Li1,2, Rong Ma2, Muhammad Khan3*, Chenchen Liu2, Xiaolin Cui2 and Yongming Li1,2*
...wn to exhibit anticancer activity in various human cancer cells. However, the anticancer mechanism of piceatannol is not well studied. In the meantime, cisplatin (CDDP) is the first line treatment for some tumors. The present study was aimed to explore the cellular targets and anticancer mechanism of piceatannol in human osteosarcoma U2OS cells. Cell proliferation was measured using CCK-8 assay and colony forming assay. Flow cytometry was used to determine apo...
Muhammad Suleman1,*, Abu ul Hassan Faiz2, Muhammad Shahbaz2 and Ayesha Riaz3
...xylanase showed specific activity of 41.22 IU/mg protein. Partially purified xylanase showed protein content of 80.6 mg/ml. The novelty of this study is basic sources used are indigenous and cheap for production of xylanase.
...
Lin Qi, Lu Li, Danyang Chen, Mingxiao Liu, Yan Wu and Wei Hu*
...encer. The antibacterial activity of the protein monomer in antlerplate was studied by disc diffusion method, and the antibacterial ring diameter of each antibacterial agent was measured to determine its antibacterial ability. The molecular mass and purity of this polypeptide was 18.970kDa and 90%. Amino acid sequence analyses indicated that the N-terminal amino-acid sequence of this monomeric peptide was AAQSLLACGAARLYKIIQQWPHYRR. The results showed that unde...
Sajida Sabahat1, Asif Nadeem1,*, Maryam Javed1, Muhammad Yasir Zahoor1, Shahid Nabeel1 and Abu Saeed Hashmi2
...ding capacity and alters activity of GH. Therefore, the GH and GHR genes are considered important candidate genes. DNA samples of Marecha camel were collected from the Camel Breeding and Research Station at Rakhmani Bhakar, Pakistan. Two significant polymorphic sites were identified in GH gene and three in GHR gene. Out of these, T1720A polymorphism in GH and A211927G polymorphism in GHR genes changed the amino acid from leucine to histidine and methionine to ...
Mohammed Al Bratty1,*, Hassan A. Alhazmi1,2, Desam Nagarjuna Reddy3, Abdul Jabbar Al-Rajab3, Sadique A. Javed1 and Zia ur Rehman1,4
...remarkable antimicrobial activity against certain strains of bacteria and yeasts. In general, significant antimicrobial activity was recorded against gram positive bacteria (zone of inhibition: 16.3±0.35–30.6±0.11 mm; MICs: 1–4 μg/ml); while gram negative bacteria (zone of inhibition: 10.1±0.23–17.2±0.13 mm; MICs: 4–16 μg/ml) and yeasts (zone of inhibition: 9.1±...
Nazish Mazhar Ali1, Asma Ashraf 2*, Iram Liaqat2, Bushra Mazhar2, Shaukat Ali2 and Saiqa Andleeb3
...ve medium. Antibacterial activity of different compounds was observed against the pathogenic bacterial isolates. Minimum Inhibitory Concentration (MIC) test of different kinds of honey was performed against the isolated bacterial pathogens. The antibacterial activity of leaf extract of Azadirachta indica (Neem Plant) was also checked against the pathogenic bacterial isolates. The bacterial pathogens isolated from eye ...

Sameera Arshad1*, Arshad Mahmood Malik2 and Iftikhar Hussain3 

...ing periods of high bird activity.  

...
Qi Ren, Shufeng Sun, Chen Niu, Yuhong Li, Yingzhi Chong, Biao Li, Guoying Zheng and Fumin Feng*

 

...estigated. Dehydrogenase activity was detected by a lactate dehydrogenase assay kit; superoxide dismutase (SOD) activity and malonaldehyde (MDA) concentration were detected by a total superoxide dismutase test kit and a malondialdehyde test kit. Genomic DNA and RNA were extracted from cells; Methylation was inhibited by treating HL7702 cells with 5-aza-2’-deoxycytidine (AZA), and the level was analyzed via the methylat...
Yating Cheng1, Wenlong Shi1, Xue Xiao2, Qirong Zhang2, Qihao Zhang1, Zhijian Su1, Qi Xiang1,2* and Yadong Huang1,2
...tains the solubility and activity of the α subunit. In this study, two plasmids were used to produce an active human P4H tetramer (rhP4H) in Pichia pastoris. The P4Hα was cloned into pPICZαA, and PDI was cloned into PHIL. Real-time PCR showed that the P4H gene was expressed at the mRNA level. SDS-PAGE and western blotting analysis showed that the secreted expression of rhP4H was achieved successfully in P. pastoris GS115 cells. ...
Rafiq-ur-Rehman1*, Zahoor Ahmad1, Wiqar Ahmad2, Muhammad Mansoor3 and Shah Masaud1
...nd environmentally sound activity in crops production. Response of mungbean cultivar (Inqalab Mung) inoculated with four strains of rhizobium (TAL-634, TAL-169, NARC-BK and NARC-M) was evaluated during two consecutive years 2015 and 2016 at the Agricultural Research Institute, Rata Kulachi, Dera Ismail Khan (31º 49/ N latitude and 70º 55/ East longitude), Khyber Pakhtunkhwa, Pakistan. The current experiments were carried out in a randomized complete ...

Nosheen1, Sajid Abdullah1, Huma Naz2* and Khalid Abbas1 

...b+2) on peroxidase (POD) activity in tissues viz. liver, gills, kidney, muscle, heart and brain of fish Catla catla exposed for 4-day. After each sampling (24-hr interval) fish were dissected and required organs were obtained. Results showed that the POD activity was augmented in all selected organs of Pb+2 exposed fish in relation to control. The POD activity in organs of fish followed th...

Muhammad Naeem Khan* and Asad Jan 

...nsiderable antibacterial activity against Xanthomonas campestris and Pseudomonas aeruginosa causing 12.6±0.54 mm and 20.6±0.53 mm zone of inhibition, respectively which was analogous to that of cefixime, used as standard drug. In case of antifungal activity MCE hindered the growth of Fusarium oxysporum effectively, causing 19.3±0.41 mm zone of inhibition, while the activity

Sibgha Noreen*, Sumrina Faiz, Muhammad Salim Akhter, Kausar Hussain Shah 

...iological, and oxidative activity of sunflower crop could be enhanced by aerial spray of proline at the rate of 200 mgL-1 under saline environment. 

...

Fazle Akbar and Sahib Alam* 

...d the influence of water activity (aw) and storage time on total fungal and Fusarium counts and mycotoxins zearalenone (ZON), trichothecenes type-A (i.e. T-2 and HT-2) and trichothecenes type-B (i.e. DON, 3-ac DON, 15-ac DON) production in maize grains. Water activity of the grains was adjusted to 0.85, 0.90 and 0.95 aw and the samples were stored at 25°C for 45 days. The control samples were kept without any aw modifica...
Muhammad Furqan Shahid1*, Tahir Yaqub1, Muhammad Yasin Tipu2, Asim Aslam2, Saima Yaqub1, Aziz-ul-Rahman3, Muzaffar Ali1
...up>th DPI. Cross reactivity of antiserum response toH9N2 was compared among reference isolates when challenged in broilers, Partridge origin anti-H9N2 antibodies showed varied hemagglutination inhibition results (4log2 to 15log2) when cross reacted with different antigens, suggesting H9N2 viruses are circulating with different antigenic characteristics. Sero-biochemical analysis of blood collected at 7th DPI revealed an i...
Fizza Anwar1, Muddassar Zafar1*, Zahid Anwar1, Raja Tahir Mehmood2
... time. The antimicrobial activity of secondary metabolites was tested against Streptococcus aglactaie, Streptococcus pyogene, Escherichia coli and Proteus mirabilis. The fungus Aspergillus niger was found best among all tested strains as it produced maximum amount of antimicrobial agent Tautomycetin. The antimicrobial activities were determined through disk diffusion assays and Tautomycetin was observed as best antimicrobial agent h...
Tanzeela Riaz, Fiza Sana-Ullah Khan, Farah Rauf Shakoori
... hydrolysis with maximum activity ratio. These isolates (MBL-SP02, MBL-CW01 and MBL-GN02) produced maximum units of mannanase activity, i.e., 9.474, 7.364 and 3.568 U/ml in quantitative, respectively.These best producers were further selected for optimization of cultural conditions for mannanase production. They all produced maximum mannanase units in M1 medium after incubation of 48 hours. The MBL-CW01 was best manna...
Naila Riaz1, Hafiz Muhammad Tahir2, Muhammad Khalid Mukhtar1, Ali Hassan2, Shaukat Ali2, Shafaat Yar Khan1
...and acetylcholinesterase activity of selected venom fractions were determined using of Musca domestica adults. Only one fraction (out of 7) from H. tamulus venom and one fraction (out of 5) of A. finitimus venom were selected on the basis of their maximum yield. The approximate molecular weights of these selected venom fractions were determined by SDS Gel electrophoresis. The molecular weight of venom fractions of H. tamulus and ...
Sobia Nazir1, Muhammad Irfan1*, Muhammad Nadeem2, Hafiz Abdullah Shakir3*, Muhammad Khan3, Shaukat Ali4, Quratulain Syed2
... to observed the maximum activity of cellulase using Box-Bhenken design of response surface methodology. Maximum activity of CMCase (0.700 IU/gds/min) and FPase (0.260 IU/gds/min) was observed on 4th day with inoculum size of 1% and medium volume of 1ml (for 5g substrate). The proposed model was highly significant as depicted by ANOVA. The results recommended that seed pods of Bombyx ceiba play important ro...
Hafiz Muhammad Tahir*, Palwasha Jabeen, Chand Raza, Shaukat Ali
...hailed to have antitumor activity and has also been widely used in different cosmetics. The major hindrance in using spider silk for different purposes is due to its small obtainable amount. Efforts are being made to overcome this problem by modern biotechnological techniques including of making transgenic organisms.
...
Hafiza Sadaf Zahra1, Asia Iqbal2, Sayyeda Hira Hassan1, Hafiz Abdullah Shakir1*, Muhammad Khan1*, Muhammad Irfan3, Chaman Ara1, Shaukat Ali4
...inhibits transcriptional activity by methyltransferase enzyme which results in inactivation of tumor suppressor genes (TSG), while in hypomethylation, demethyltransferase enzyme causes the activation of oncogenes by promoting transcriptional activity. Contrary to DNA methylation, histone acetylation and deacetylation results in chromatin opening and closing, respectively; leading to transcriptional activation and inactivatio...
Muhammad Shoaib1,3*, Arif Ismiyev2,Khudaverdi Ganbarov3, Aygun Israyilova3 and Sajid Umar4
... vitro antimicrobial activity against Gram-positive bacteria, Gram-negative bacteria and fungi by agar well diffusion method. In second step, minimum inhibitory concentration of test compounds was determined against bacterial species by using resazurin microplate assay. All the tested compounds exhibited variable antimicrobial properties against various test cultures. All the compounds showed stronger antimicrobial activity<...
Barkat Ali1,2, Wasim Sajjad1,2,3, Imran Khan1, Muhammad Rafiq1, Sahib Zada1, Aamer Ali Shah1 and Fariha Hasan1,*
...n them for antimicrobial activity. The isolates were identified based on 16S rRNA sequence analysis. Antibacterial activity of the isolates was checked against ATCC strains E. coli, Staphylococcus aureus, and Pseudomonas aeruginosa. Seven different types of antibiotic discs were used to check the intrinsic resistance of all the isolates to various antibiotics. Interestingly, most of the iso...
Fariha Latif1*, Muhammad Javed2, Hammad Ahmad Khan2 and Khalil-Ur-Rehman3
...cant decrease in the CAT activity was also observed. Liver showed a significantly higher activity of all the three enzymes that could be due to its actively metabolic nature. Pb can inhibit the functional properties of CAT by disrupting disulfide bond. Moreover, the interference of Pb in the activity of SOD was also reported during present investigation. Therefore, this study provides an i...
Saman Muhsin Abdulkareem* and Nadir Mustafa Nanakali
...ve stress, liver enzymes activity and the expression of cytochrome P450 1A1 (CYP1A1) against hepatotoxicity induced by 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD) in male rat. Thirty adult male Wistar rats randomly divided into five equal groups. TCDD and QCT were orally administered at the dose of 10µg/kg /day and 20 mg/kg/day, respectively by gavage dissolved in corn oil for 90 days. At the end of the study, animals were sacrificed and their l...
Awais Bin Shahid1, Moolchand Malhi1,*, Saeed Ahmed Soomro1, Muhammad Giasuddin Shah2, Nazeer Hussain Kalhoro3, Asmatullah Kaka4, Rajoo Mal1, Muhammad Awais Soomro1Saba Parveen Samo1 and Muhammad Nawaz Sanjrani5
...ione peroxidase (GSH-Px) activity increased (P < 0.05) in ruminal epithelium of SY goats compared to C. The present study demonstrated an improvement in ruminal fermentation, and hyperplasia and enhanced GSH-Px activity in the ruminial epithelium of goats fed SY supplemented diet compared to control that were fed diet without SY supplementation. 
...

Awais Ahmed Khan1*, Zafar Iqbal1 and Muhammad Atiq2 

... acid showed highest POD activity (8.4 U/min g protein), SOD (6.96 U/ min g protein) and TPC (3.21 mg GAE/ 100g of sample) as compared to control where POD (1.13 U/min g protein), SOD (1.46 U/ min g protein), and TPC (1.14 mg GAE/ 100g of sample). Amount of hydrogen peroxide (H2O2), the signaling molecule was also significantly increased (30.33 mmol/ mg FW) and catalase (CAT) was higher (91 U/min g protein) in fruit treated with ascorbic acid as compared to co...
Kadry A. El-Bakry1, Lamiaa E.M. Deef1*, Lotfy Z. Habbak1 and Samia S. El-Naeli2
...e (MDA) but decrease the activity of superoxide dismutase (SOD) enzyme. On the other hand, in patuilin injected rats and treated with ginger, the activity of ALT, AST and SOD were improved and level of MDA was decreased significantly. The liver and kidney tissues showed markers of improvement after treatment the patulin rats with ginger. In conclusion, treatment with ginger can protect liver and kidney form the toxicity indu...

Saleha Ashfaq1, Manzoor Hussain1, Nazish Bibi2, Jan Alam1, Muhammad Junaid2 and Sabi-Ur-Rehman3*

...imicrobial and cytotoxic activity of Haplophyllum gilesii (Hemsl.) C.C. a narrow endemic plants of northern areas of Pakistan. The antimicrobial potential of H. gilesii extracts in different solvents was assessed using agar well diffusion method against bacterial and fungal strains, while cytotoxic activity was studied in the methanolic extract using brine shrimp’s lethality assay. All the extracts showed significant b...
Nurlybay Kazhgaliyev1*, Talgat Kulmagambetov2, Dulat Ibrayev1, Saule Bostanova1 and Zhanat Titanov1
...oups had 0.19 functional activity index; as for the other indices, animals of group I and II groups (Hereford heifers) had a comparative advantage, they were more active and spent more time in moving and feed eating. Taken together, different breeds can be acclimatised and adapted to the varying climatic conditions through generations and thus presents practical strategy to secure food for growing population in the country.
...

Muhammad Rehan3, Asim Aslam3, Javeria Umber4, Muti-ur-Rehman Khan3, Waqar Azeem3, Hassan Aftab5, Ahsan Anjum3, Muhammad Abid6, Abdul Hameed Khan3, Hafiz Hasnain Ayoub5, Altaf Hussain2 and Muhammad Farooq Khalid1* 

... responses by modulating activity of monocytes, dendritic cells, macrophages and activation of T and B lymphocytes. Vitamin D modulates cytokine response and anti-microbial peptides (AMPs) production which boost innate immune response. Hypovitaminosis D is a significant risk factor for infectious and non-infectious diseases however its exact mechanism is still unknown, but low levels of vitamin D has been detected in different diseased cases. Recent investigat...
Gasem Mohammad Abu-Taweel
...ular coordination, motor activity, blood parameters and liver structure alterations. On the first day of pregnancy, 30 pregnant mice were equally divided into three groups. Tap water was provided to the control group (Group I). Group II and Group III animals were orally received 5 and 10 ppm of HgCl2.The treatment started the first day of pregnancy and continued to the day 15 after birth thearafter the dams were sitched to tap water. The behavioral ...
Tian-Yi Zhao1, Zi-Qing Liu2, Shu-Fei Ma3, Bo-Yang1, Fan-Fan Guo1 and Ming-Hua Duan1*

 

...applied in vivo, and the activity of the NF-κB signaling pathway and concentrations of TNF-α, IL-6, and IL-1β were measured. The results demonstrated that biatractylolide can reduce apoptosis in hippocampal cells, prevent and improve the cognitive decline induced by Aβ, prevent the morphological changes in hippocampal nerve cells and can reduce the activation of NF-κB signal pathway in vivo. Taken together, biatractylolide appeared ...
Ju Zhang1,2, Dong-Sheng Jia3, Shi-Hao Zhao1,2, Xiao-Liang Xie3, Hong Chen4 and Hai-Feng Li4,*

 

...matodes. The antioxidant activity of HGQ was investigated by determining reactive oxygen species (ROS) level, paraquat-stress survival rate, malondialdehyde (MDA) content as well as superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx) activities.We observed that HGQ exerted little effect on the growth of wild-type N2 nematodes at concentration < 0.6 mg/ml, and 0.05 mg/ml of the HGQ significantly prolonged the lifespan and reduced the ...
Derya Kocamaz* and Elif Oruc
...icide mixture group, the activity of antioxidant enzymes was highest and the level of hormones was lowered. The group of the mixture pesticide showed the highest lipid peroxidation and protein carbonylation than only thiamethoxam or λ cyhalothrin exposure. In conclusion, the mixture of the insecticides showed a more toxic effect on the gonad of tilapia compared to individual pesticide exposures. In addition, the depuration period of 7 days was not adequ...
Rafia Sadaf1, Ishrat Younus2*, Sidra Maqbool2, Talha Bin Fayyaz3Sarah Jameel Khan1, Sidra Siddique1 and Rida Fatima1
...oxicity and anti-anxiety activity of ethanol extract of Pulsatilla nigricans leaves. The acute oral toxicity shows that, plant extract up to 5000 mg/kg produces no signs and symptoms related to toxicity and also no mortality was observed. Antianxiety activity of Pulsatilla nigricans was examined by using elevated plus-maze paradigm and hole-board paradigm in rats at two different doses i.e. 250 and 500 mg/kg, a...
Fatima Hashim Abbas1,2* and Alaa Tareq Shakir Al-Hassnawi1
...on (MDA level), catalase activity (CAT), total antioxidant capacity (TAC) and reactive oxygen species (ROS) were measured in the serum of all studied groups. MDA levels were significantly higher (p≤0.05) in aborted women with T. gondii compared to negative control. MDA levels were also significantly higher (p≤0.05) among aborted women with Cytomegalo virus compared to negative and positive control groups. All aborted women had significantly higher...
Ahmet Ozer Sehirli1,2, Serkan Sayiner3*, Ayliz Velioglu-Ogunc4, Nedime Serakinci5, Emel Eksioglu-Demiralp6, Berrak Yegen7, Feriha Ercan8 andGoksel Sener2
...tate dehydrogenase (LDH) activity, cytokines (TNF-α, IL-1β, IL-6) concentrations, urinary volume, creatinine, and both serum and urinary electrolyte levels were measured. In addition, the apoptosis rate of white blood cells was analysed from plasma samples. Tissue samples from the brain, heart, aorta and kidneys were used for analysis of the collagen content besides tissue luminol, lucigenin, malondialdehyde (MDA) and glutathione (GSH) levels. A sig...
Boxin Dou, Ying Liu*, Yumeng Liu, Lili Fan, Yongqiang Ma, and Yanguo Shi
... converting enzyme (ACE) activity of the rice bran (RB) and comparison of its activity with selected commercial antihypertensive pharmaceutical. A new peptide with ACE inhibition properties was obtained by using alkaline protease to enzymatic hydrolysis of RB crude protein purified by ultrafiltration, size exclusion chromatography and RP-HPLC. Using consecutive chromatographic techniques successively, the acidic hydrolysates...
Larysa Kladnytska1, Anatoliy Mazurkevych1, Natalia Bezdieniezhnykh2Oleg Melnyc1, Sergiy Velychko3, Mykola Malyuk1, Vasyl Danilov1Yuriy Kharkevych1 and Magdalena Gryzinska4*
...roperties, proliferation activity, cell signaling, interaction and mobility. The level of expression of these proteins remains high in the stem cells culture also at the Xth passage, although it is significantly lower in relation to the IVth passage. At the IVth passage adipose stem cells are characterized by average values of β-catenin expression – 97,7 ± 8,5 points, and low values of CD44 expression – ...
Xuhui Zhang1, Zhiyuan Sun2, Jinfeng Cai1, Guibin Wang1, Zunling Zhu1, Linguo Zhao3 and Fuliang Cao1,*
...roxide dismutase (T-SOD) activity of birds from group FR3 was significantly increased (42d) compared with NF group. Additionally, the expression of antioxidant enzyme genes including nuclear factor erythroid 2-related factor 2 (Nrf2), heme oxygenase 1 (HO-1), SOD, and glutathione peroxidase (GPx) were improved by FR supplemented into the broiler diets. Based on these results, FR could be acted as a beneficial feed additive with antioxidant capacity a...
Naseeb Ullah1, Assad Ur Rehman1, Aamir Khan1, Rabia Noushin2Shahid Naiz Khan1, Syed Ishtiaq Anjum1, Sajida Afzal1, Asma Naseem1Kenza Javed1, Ujala Rauf1 and Kalim Ullah1*
...ge ruminants). FMD viral activity both in small and large ruminants were high in the month of December (20% small ruminants and 16% large ruminants) followed by January, February, March, April and May. The Seroprevalence of FMD was significantly lower in both small and large ruminants having good health status (16.35% in small and 10% in large ruminants) while high in those having weak health status (17.91% in small and 15.7% in large ruminants). The higher se...
Qaisra Siddique1, Sajid Abdullah1, Huma Naz2*, Khalid Abbas1, Laiba Shafique3

 

...ione S-transferase (GST) activityand total protein contents (TPCs) in tissues viz. brain, gills, kidney, heart, muscle and liver of Labeo rohita kept under sub-lethal dose (4.13 µgL-1) of chlorpyrifos. Fish was kept under chlorpyrifos stress for two months and samples were collected on weekly basis. It was noted that GST level varied significantly with duration. The GST level was raised in first 28 days after that it was dropped off up ...

Grigory Antonovich Nozdrin1*, Regina Gabdrahmanovna Utkina2, Anastasia Aleksandrovna Lelyak2 and Yana Viktorovna Novik1 

...fowl, behavior, physical activity, water, and feed consumption were monitored. At the end of the experiment, autopsy and morphometry of internal organs were assessed. No toxic effect of the experimental sample (Vetom 20.76) was observed during the experiment. The fowl in the experimental groups had positive dynamics on the weight gain, growth, and development even at the dosage of the preparation of 5,000 µl/kg. During the general autopsy, no p...
Sikander Ali* and S. Wajiha Khalid
...enzyme exhibited maximum activity at pH 6 after 72 h of fermentation (158±0.39 U/ml). The partial purification of the enzyme was done with ammonium sulphate (20-80 %) followed by dialysis which resulted in 21 % purification from the crude enzyme extract. The molecular weight of enzyme was found to be 86 kDa, as determined by SDS poly-acrylamide gel electrophoresis. 
...
Quratulain1, Ata-ul-Mohsin1, Muhammad Naeem1, Ghulam Shabir1, Muhammad Khalid Rafique2 and Rashid Mahmood2*
...abaci showed maximum activity at 24 oc which shows positive correlation between temperature and thrips development. Considering categorization of ten onion accessions against thrips, Red Imposta was found as highly resistrant, early red, Chiltan, Nasar puri as resistant cultivar whereas Swat 1, Virio7 and 8, Phulkara, Saryab red were found susceptible while Hazara grouped in highly susceptible category due to maximum thrips infestation. Visual a...
Aamir Mushtaq1,2, Rukhsana Anwar1 and Mobasher Ahmad1,2,* 
... along with anti-oxidant activity. Anti-amnesic activity was found by behavioral and biochemical studies for which male albino mice were grouped into seven groups. Mice were subjected to elevated plus maze, hole board and light dark paradigm on (day 7th and 8th), for behavioral studies after which their brain were removed by decapitation for biochemical assessment. Results indicated the existence of tot...
Ambrin1*, Ghulam Dastagir1, Jehan Bakht2 and Muhammad Adil1
...i>showed good antifungal activity against Aspergillus niger, Penicillium notatum. Minimum MIC value was shown by ethyl acetate and ethanolic extracts of Z. mauritiana against Aspergillus fumigatus and Aspergillus niger. The ethyl acetate and ethanolic extract of O. biennis revealed maximum antifungal activity against Aspergillus niger, Aspergillus flavus and Aspergillus fumigatus....
Yuhong Li1, Dongxue Wu1, Xue Wang1, Mi Zhang1, Hanyu Zhu1, Zhe Shi1 and Fumin Feng1,2*
...ually increased, and the activity of superoxide dismutase (SOD) gradually decreased, suggesting that oxidative stress reaction occurred in all drug groups. Compared with the baseline group, the mRNA and protein levels of NF-κB and TNF-α in the H group showed an increasing trend, and p-NF-κB and p-IκB also showed an increasing trend. However, these indicators increased first and then slightly decreased in the R, Z and HRZ groups. Among t...

Ghulam Mohi Uddin Paracha* and Yasser Durrani 

... content and antioxidant activity) and sensory evaluation of blends was carried out. The treatments in this study included BPo [peach persimmon blend (6:4)], BP1 [peach persimmon blend (6:4) + potassium sorbate (0.1%)], BP2 [peach persimmon blend (6:4) + potassium metabisulphite (0.1%)], BP3 [peach persimmon blend (6:4) + sodium benzoate (0.1%)], BP4 [peach persimmon blend (6:4) + potassium sorbate (0.05%) + potassium metabisulphite (0.05%)], BP5 [peach persim...

Muhammad Usman Ghazanfar1, Waqas Raza1*, Waqas Wakil2,3, Imtiaz Hussain4 and Misbah Iqbal Qamar

...e and polyphenol oxidase activity than water treated plants. Enzymes produced as result of treatment with elicitors are responsible for protection against late blight and sucking insect pests. The inducers can be used for disease and insect pest’s management. 

...

H. Liu1, X.P. Tang1, R.J. Fang1,*, F.Yi2, C. Zhang2, R.Q. Yang1, F. Sun1 and S.Y. Zhou1 

...ance and serum Cu-Zn SOD activity in piglets. A total of 288 (144 castrated males and 144 females) healthy post-weaned at 23-day-old piglets (Duroc × Landrace × Yorkshire) with an average body weight of (8.79±1.15) kg were randomly divided into 6 groups with 8 replicates in each group, and 6 piglets (3 castrated males and 3 females) per replicate. Control group was fed a basal diet, experimental groups were fed diets supplemented with copper...
Tehreem Usman1, Sajid Abdullah1, Huma Naz2*, Khalid Abbas1, Laiba Shafique3 and Qaisra Siddique1
...ehaviour, catalase (CAT) activity and total protein contents (TPC) in Ctenopharyngodon idella under binary mixtures of insecticides viz. endosulfan(ES)+chlorpyrifos(CPF) and endosulfan(ES)+bifenthrin (BIF). The fish behaviour was observed from both treated and control groups. Fish under exposure of insecticides mixtures exhibit abnormal behaviour and tried to jump out from water, come to surface and gulp air, showed increased opercular movement and erra...

Gulnaz Parveen1*, Salma Gul2, Muhammad Ather Rafi3, Ashfaq Ali Khattak4 and Hikmatullah Jan

...ving a strong antifungal activity for different fungal pathogens and have compounds are more effective to promote the growth of tomato plant. Tomato (Lycopersicum esculentum) plant is highly susceptible to root rotting fungi causing huge losses each year in Pakistan. Acacia nilotica used as a biofertilizer and Significant (p< 0.05) enhanced the growth of tomato plants. Infection % of all test fungi included Fusarium solani, Fusarium oxysporum, Macrophomina ...

Anurag Sharma*, Naresh Kumar, Geetanjali Singh and Anika Sharma 

...ifungal and galactagogue activity. The commercially available drugs pose health threats and prove detrimental to both human and animal health. The traditional use of herbal preparations suggests that they are safe and effective, however, scientific validation is still required for many of them especially for animal use. The phyto-pharmacological research on these two natural products show a ray of hope for the discovery of new active compounds with a novel str...

Ehsan-Ul-Haque1, Akbar Hayat1*, Muhammad Asim1, Sajjad Hussain2, Muhammad Shakeel Hanif3, Muhammad Zubair1, Muhammad Abdullah Jamil1 and Faheem Khadija1 

...n, crude fat and in DPPH activity respectively. The study depict that incorporation of salts to wax in substitution to the fungicide is an effective application to control postharvest citrus fruit decay with perks of safety and convenience. 

...

A. S. M. El-Nuby1† , S. A. Montasser2 and I. A. El-Khadrawy

Control of root-knot nematodes using wild plants colonized Sinai, Egypt
...> The antinematodal activity of some wild plant extracts located in North and South Sinai, Egypt was examined against root-knot nematode (RKN). The selected seven plants viz., Artemisia judaica, A. monosperma, Bassia muricata, Cornulaca monacantha, Salsola kali and Zygophyllum album with different dilutions (25%, 50%, 75% &100%). The potent nematicidal efficacy observed in the extract of A. judaica followed by A. monosperma. In vivo trial post inocula...

 K. Abbasi 1 , R. Wick2† and D. Zafari1

Chitinase activity of biocontrol fungi cultured from the golden potato cyst nematode, Globodera rostochiensis
...ates with high chitinase activity were selected for further characterization. Of the 10 selected isolates, three chitinase enzymes were evaluated using three substrates. Based on the results of our chitinase assay, Beauveria bassiana, Lecanicillium muscarium, Paecilomyces sp. and Trichoderma atroviridae had the highest activity. We selected these four isolates to determine the optimum pH, temperature, and reaction time. Zymo...

Aqeel Nawaz1, Muhammad Ali Kamran1 

PARAMETRIC SENSITIVITY ANALYSIS OF CONVEX STAR PORT PROPELLANT GRAIN FOR SOLID ROCKET MOTOR
...olid rocket motor design activity. Ballistic quality of a designed grain
can be evaluated by two vital indexes known as neutrality and sliver content. Sliver content results in tail-off of
the thrust-time curve. These two measures of merit are an important part of acceptable grain design. This paper is
restricted to the study of convex port star grain geometry and describes parametric evaluation to assess the effects
of seven indepe...

Hamza Tariq1, Imran Hayat1, Saima Rafiq1*, Aqsa Qayyum2 and Sohrab Qayyum1 

... vitamin C), antioxidant activity, total phenolics, and sensory evaluation (color, flavor, taste, overall acceptability) during storage (90 days) at ambient temperature for consumer acceptability. An increase in titratable acidity, vitamin C, total phenolics and antioxidant activity was observed with increasing the concentration of autumn olive in the beverage blends while a decreasing trend was observed for pH, reducing sug...

Parsa Riaz and Muhammad Naeem*

Digestive Enzymes Activity with Gut Morphometric Parameter of Carnivorous Fish Wallago attu (Siluridae, Siluriformes)
...inly reported on overall activity of lipase, amylase and protease of Wallago attu. To the best of our knowledge, this is the first study on Wallago attu related to gut morphometrics that evaluated digestive enzymes with reported literature behalf of their species feeding habits. Gut morphometric parameters included first time in relation to Wallago attu morphology as Relative gut mass, length and Zihler’s Index are basically explored as potential indices...

Feroza Arshad*, Aftab Ahmed Memon**, Muhammad Aslam Uqaili** and Arshad Habib Malik*

SYNTHESIS OF A NOVEL ROBUST INTELLIGENT CASCADED REACTIVITY CONTROLLER FOR CANDU REACTOR
...l Intelligent Cascaded Reactivity Controller (NICRC) is synthesized for a CANadian Deuterium Uranium (CANDU) -type Nuclear Power Plant (NPP) operating in Pakistan. The designed NICRC is a cascaded configuration of reactor power and moderator level controllers composed of five sub-controllers. The proposed NICRC is designed using intelligent soft computing technique. The original reactivity controller of C...

Arshad Habib Malik*, Aftab Ahmed Memon** and Muhammad Rafiq Khan***

DYNAMIC MODELING AND CONTROLLER DESIGN FOR NUCLEAR POWER PLANT
...control valve and reactivity system. The nonlinear model is characterized by 15 state variables and one input. This higher order nonlinear model is linearized at full power operating point. A standard higher order state space model is realized for controller design purpose. An advanced discrete controller is synthesized for state space model of PHWR using fast output sampling methodology. Noise sensitivity is a typical problem with this typ...

Ghulam Murtaza1, Ghulam Sarwar1*, Muhammad Ashraf Malik2, Muhammad Zeeshan Manzoor1, Ayesha Zafar1 and Sher Muhammad3 

...ing normal physiological activity and productive capacity of crops. The saline water irrigation leads to salt accumulation in the vicinity of roots which results in reduced yield along with soil deterioration. Organic matter application can prove helpful in keeping the salt level low in root rhizosphere. To check the efficacy of organic matter in mitigating the harmful impacts of salty water irrigation on soil characteristics, this trail was conducted. The irr...

Haiyan Yang1, Hongxia Liu1, Wenlong Wu1*, Weilin Li2 and Lianfei Lyu

... restored. Moreover, SOD activity increased gradually under drought stress, except for the day 15. After re-watering, SOD activity was still at higher level. Under drought treatment, POD activity and levels of AsA and GSH first ascended and then followed by a decline. After re-watering, they all decreased, but AsA and GSH levels were remain higher than the controls. The results indicated t...

Syeda Farzana Bibi* and Siraj-ud-Din

Fluorescence Analysis, Extractive Values and Cytotoxic Screening of Crataeva adansonii DC Leaf and Bark through Brine Shrimp Larvae Assay
...d through cytotoxic activity. Brine shrimp larvae assay was conducted for this purpose. Extractive values of leaf and bark parts were estimated using n-hexane, chloroform, ethanol, methanol, water, and ether as a solvent. 10g of plant powder was dissolved in 200 ml solvent during various extract preparations Fluorescence study was conducted after treating the powder drug with different reagents including ethanol, methanol, acetic acid,...

Mazhar Abbas1*, Kishwar Jam1, Rashid Iqbal Khan1, Muhammad Zafar-ul-Hye2, Tariq Rafique3 and Zahid Mahmood

... increase of antioxidant activity by upgrading superoxide dismutase activity (64.42 U mg-1 protein), peroxidase activity (1.90 µmol min-1 g-1 protein), catalase activity (37.81 nmol-1 g-1 protein) and protein (6.28 mg g-1 fresh weight) contents. These commercial plant products based on amino acids enriched macro and micronutrients as well as acetyl...
Anum Feroz1, Abdul Rauf Shakoori2 and Farah Rauf Shakoori1*
...tylcholinesterase (AchE) activity was significantly decreased (28.94 and 42.42%) in the 4th instar larvae of Lab-S population after treatments with bifenthrin and bifenthrin: chlorpyrifos combination 3:1, respectively. After exposure to chlorpyrifos and bifenthrin: chlorpyrifos combination 1:3 the AchE activity was increased 45.24 and 64.28%, respectively. This increase was much more prominent in the 6th
Ayesha Noreen1, Amina Elahi1, Dilara Abbas Bukhari2 and Abdul Rehman1*

 

...cellular and its optimum activity recorded was determined as 730 and 750µM/min (calculated by both Safranine O spectrophotometric and molybdene blue methods) at pH 7 and 37°C in the presence of Zn2+ as cofactor. The protein profile of B. cereus 3.1S, showed two bands of approximately 14 and 70 kDa, which had their possible role in arsenite oxidation. This was confirmed by transforming E. coli DH5α with plasmid DNA of
Gregory Ejikeme Odo1,*, Juliana Ekenma Agwu1, Nkechi Nweze2, Clara Ikegbunam2,Felicia Ekeh N1, Vincent Ejere1, Ngozi Ezenwaji1, Reginald Njokuocha2, Godwin Ngwu1 and Fabian Okafor1
... The reduced significant activity of these markers suggest that the ethanolic leaf extract of D. erecta offered some protections against diseases related to the muscles. The significant reduction of AST level has further eliminated any leakage of the enzyme in the liver due to hepatic injury in the treated rats. Previous biochemical studies have also confirmed the non toxicity of the plant extract of D. erecta to the kidney.
...

Muhammad Jan1*, Tanveer ul Haq2, Hina Sattar3, Madiha Butt4, Abdul Khaliq5, Muhammad Arif6 and Abdul Rauf

...er rainfed condition the activity of all enzymes increased among all genotypes. The chick pea genotypes, GGP-1260, PGP-1426 and PB-1 were observed as drought-tolerant ones on the basis of biochemical, morphological and physiological parameters and these can be recommended for rain-fed areas crop selection. 

...
Shikun Ge1, 2, Yanli Yang3, Brindha Chelliappan4, 5, Antonysamy Michael5, Fagang Zhong1 and Xiaoying Zhang1, 2, 3, 4*
...der preparations) on the activity of IgY antibodies was investigated. The results showed that IgY was stable below 70 oC, and the activity was significantly lost when it exceeded 70 °C; IgY was relatively stable in the range of pH 4-10, and the activity was significantly lost beyond this range; IgY had certain resistance to pepsin and trypsin. Among all four purification met...
Safia Arbab1, Rehana Buriro1, Shams Uddin Bhugio1, Atta Hussain Shah2,  Jamila Soomro3,Qudratullah Kalwar4, Saqib Ali Fazilani1 and Waseem Ali Vistro5*
...oration of antibacterial activity of the Aloe Vera in different families of animals. However, very limited information is documented about antibacterial activity of Aloe Vera in equines. The present study was designed to check the antibacterial activity of the Aloe Vera against most pathogens found in the wounds of donkey. For this purpose, two different concentrations 30 µl and 60 &...
Huma Abbas1*, Nazir Javed1,Muhammad Kamran2, Sajid Aleem Khan1Hira Abbas3, Ehetisham-ul-Haq2, Abdul Jabbar1, Mehwish Naz1 and Ihsan Ullah4
...he induction of systemic activity by using modified split root technique. Efficacy of different application methods; soil drench and root dip was also tested. Results revealed that all the chemicals have more or less systemic effect against M. incognita. Cartap was found to be more effective in reduction of egg masses followed by Virtako in both treated and untreated root portion. Number of egg masses was reduced significantly in Cure and Azadirachtin i...

Muhammad Ahsan Naseer1, Mehdi Maqbool1, Saima Rafiq2*, Noosheen Zahid1, Abdul Hamid1 and Syed Zulfiqar Ali Shah1

Comparative Analysis of Physical and Biochemical Attributes of Edible Fig (Ficus carica L.) Collected from Three Districts of Azad Jammu and Kashmir Located at Different Elevations
...phenolic and antioxidant activity). Results showed that wild figs obtained from diverse localities have different attributes in terms of physical as well biochemical properties. Maximum fruits weight (6.24 g), fruits diameter (24.09 mm), and neck length (9.51 mm) was observed in fruits harvested from Arja location of Bagh District, while the minimum fruit weight (2.48 g), fruit diameter (16.69 mm), and neck length (2.81 mm) was observed in fruits harvested fro...

Tahseen Ullah* and Noor ul Amin

In Vitro Antibacterial Activity of Medicinal Plant Extracts
... activities. The maximum activity was reported in C. longa which seem to be most active and lowest value was recorded in S. marianum. The maximum inhibition zone has been reported as 20 mm for the C. longa extracts and minimum has been observed for S. marianum as 13 mm. In case of concentration the maximum inhibition zone 20.58 mm was recorded with 300 mg (high concentration) while 14.6 mm was recorded for 5 mg (low concentration). In case of bacterial strains...

Khan Sher1*, Muhammad Subhan1, Muhammad Nisar2, Ali Hazrat2, Zahid Fazal1, Gul Rahim2, Imran Ahmad1, Riaz ul Haq1 and Shamia Bibi1

Genetic Diversity in Common Beans (Phaseolus vulgarus L.) Collected from Different Ecological Zones of Malakand Division (A Part of the Sino Japanese Region of Pakistan)
...xt-align: justify;">This activity was aimed to analyze the level of genetic diversity (GD) of bean landraces collected from diverse ecological zones of Malakand division, Khyber Pakhtunkhwa, Pakistan. The qualitative traits showed significant level of diversity like seed shape was determined by two alleles, seed color was defined by 13 numbers of alleles and four alleles were responsible for flower color. Similarly, the quantitative traits showed 73% diversity...
Rubina Munir1,2*, Muhammad Zia-ur-Rehman3, Muhammad Makshoof Athar1, Noman Javid1,4, Ayesha Roohi2 and Syeda Fatima Razavi2
... Free-radical scavenging activity of these compounds has been carried out by DPPH assay that showed these compounds to be effective radical scavengers. The compounds 7a, 7b, 7d, 7f and 7h have exhibited radical scavenging activity better than the reference compound BHT.
...
MA Liman1, QI Yongxiao1, Wang Wenji2* and Zhong Qianyi3*
...ay exert anti-angiogenic activity by downregulation of Vegf in zebrafish embryos, thus indicating its role as a potential therapeutic agent against cancer.
...
Hong Hu1, 2, Li Qian1, Yuanlang Wang1, Chaodong Wu1, Xiaodong Zhang1, Yueyun Ding 1*, Li Wang1, Xudong Wu1, Wei Zhang1, Dengtao Li1, Jian Ding1, Min Yang1 and Zongjun Yin1*
...terms included catalytic activity, binding, cell, cytoplasm, positive regulation of multicellular organismal process, biological regulation, cellular process, etc. There were 54 significant Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways including cytokine-cytokine receptor interaction, biosynthesis of unsaturated fatty acids, fatty acid metabolism, regulation of lipolysis in adipocytes, glycerolipid metabolism, etc. The results of differentially expre...

Syeda Farzana Bibi* and Siraj ud Din

Unraveling the Bioherbicidal Potential, Elemental Analysis and Nutritional Evaluation of Crataeva adansonii Dc Leaf and Bark
...Bioherbicidal/phytotoxic activity revealed significant results in the form of dose-dependent inhibition of frond growth. Ethanolic extract of C. adansonii exhibited 30% inhibition at 1000 μl concentration, and at the same concentration, the bark extract inhibited the frond growth by 40%. The pharmacognostic evaluation of this medicinal drug will be supportive in the detection of adulteration and quality control. Due to the herbicidal potential, it can be us...
Tehreem Zahra1, Muhammad Irfan1, Muhammad Nadeem2, Misbah Ghazanfar1, Qurratulain Ahmad3, Shaukat Ali4, Farzana Siddique5, Zarina Yasmeen6, Marcelo Franco7
...methylcellulase (CMCase) activity and filter paper cellulase (FPase) activity was obtained after 96 hours of incubation with optimum conditions of media containing 5% substrate concentration, 0.05% peptone and KH2PO concentration of 0.5% with pH 5.0 at incubation temperature of 30
Ayesha Talib1,2, Khanzadi Nazneen Manzoor1, Wajahat Ali1, Maria Saeed1, Muhammad Asif Gondal1, Malik Badshah3 and Abid Ali Khan1*
...as well as antimicrobial activity against Multidrug Resistant (MDR) bacteria is evaluated. The total formation of the Cu nanoparticles was observed visually with a color change and confirmed by the appearance of peak through UV-Vis spectroscopy analysis. The electron microscopy imaging revealed that the biogenic Cu nanoparticles were spherical in shape and had a diameter of 30-40 nm. The synthesized nanoparticles showed promising antibacterial

Kecheng Zhu1,2,3, Peiying He1, Baosuo Liu1,2,3, Huayang Guo1,2,3, Nan Zhang1,2,3, Liang Guo1,2,3, Shigui Jiang1,2,3 and Dianchang Zhang1,2,3,* 

... The results of promoter activity assays show that Almyomaker expression is notably activated by two MyoDs. Transcriptional activity of the Almyomaker promoter was observed to dramatically decrease after targeted mutation of the MyoD1 M1 and MyoD2 M2 binding sites. In summary, MyoD1 and MyoD2 play an important role in the regulationof Almyomaker expression and may promote myoblast fusion during muscle de...

Fan Sigang1, Guo Yihui1* and Xu Youhou2

...tic processes, hydrolase activity, and AMPK were enriched in the ovary, whereas those related to male organ formation and spermiogenesis were enriched in the testis. The glycosphingolipid biosynthesis pathway was identified for the first time in a mollusc testis.The present study provides the first transcriptomic analysis of C. nobilis, which will help clarify the molecular mechanisms of gonadal maturation.
...
Yujun Zhao and Jianping Fan*
...p <0.05), and the activity of Caspase-3 and Caspase-8 increased (p <0.05) in a dose-dependent manner. Hence, this can be concluded that Kanglaite injection can effectively inhibit the proliferation and induce apoptosis of SW480 cells, which may be correlated with the inhibition of Bcl-2 expression, the promotion of Bax expression and the enhancement of caspase activity.
...
Mehwish Saleem Khan
Evaluation of Changes in Zinc Levels in Patients Suffering from Cancer
...r diet, lack of physical activity or excessive drinking of alcohol. Other factors include certain infections, exposure to ionizing radiation and environmental pollutants. In this study zinc level in serum of cancer patients was observed. For this purpose, the blood of 50 cancer patients was taken from MAYO HOSPITAL Lahore. The patients are suffering from different type of cancers such as, breast cancer, lung cancer, uterus cancer, oral cavity cancer, esophagea...

Mahmoud Mohamed Ahmed Youssef* and Suzan Abd-Elazeim Hassabo

The Role of Genetic Engineering in Management of Plant Parasitic Nematodes with Emphasis on Root-Knot Nematodes: A Review
...er spp. with nematicidal activity could control root-knot nematode, Meloidogyne incognita. The development of such strains by genetic manipulation by transferring gene (s) required for saponins production is effective in increasing crop yield together with fixing nitrogen. Escherchia coli is still used as a host for the recombinant DNA technology – based industrial production of proteins and peptides to manage root-knot nematode. Mi gene resistance in to...
Yaqiu Liu1, Zhijian Wang 2, Xinhui Li 1*, Jianrong Zhao2 and Weitao Chen 1
...s on gill and gut enzyme activity in Paramisgurnus dabryanus was studied under different breathing restraint treatments. A total of 150 healthy mature individuals (mean initial body weight = 16.1 ± 3.7 g and mean initial total fork length = 13.1 ± 1.2 cm) were selected for the experiment. The experimental specimens were separated into three modes: control group (n = 50) without any stress treatments; inhibited group (n = 50) with gut respi...
Jiawei Zhang1,2, Thomas Quirke1, Shibao Wu2*, Shaoshan Li2 and Fidelma Butler1
...sitation on behavior and activity level of Humboldt penguin (Spheniscus humboldti) in captivity. The study is based on activity time-budgets from a flock of over 20 birds at Fota Wildlife Park, Cork, Ireland, gathered during daytime observations over a six month period. The results show that penguins spent most of the daytime in stationary, terrestrial locomotion, preening and swimming modes of behavior, and swimming ...

Yuan Xing, Congming Tan, Yan Luo and Wenjun Liu* 

...irflow obstruction, hyperactivity enhanced, ultra-structural remodeling, and airway mucus production. The current experimental study was aimed at scrutinizing quercetin’s inhibitory effect on airway inflammation in mice and its possible mechanism of action. The mice received varying doses of quercetin from 22-30 days (1, 10 and 50 mg / kg, p.o.) and montelukast (10 mg / kg, p.o.). Intranasal OVA has been instilled on the 21 days. Biochemical parameters, ...
Hongqun Li1*, Xiaoli Liu2*, Zongxian Han1, Shabin Wu1 and Changlei Cao1
...st account for the daily activity rhythm shifts in habitat requirements.
...
Abdul Nabi Jatt1,2*
...anase and endoglucanase) activity was highly induced in addition to exogenous AHLs. While, both exoglucanase and endoglucanase activities were radically decreased, when the growth medium was supplemented with quorum-quenching (QQ) AiiA protein. The present study, for the first time provides evidence that the QS system via AHL molecules involved in regulating the production of two different forms of an extracellular cellulase enzyme,
Javeria Afzal, Muhammad Abid, Faisal Hussain* and Alia Abbas
Wenyou Huang1, Dan Yü1, Song Huang1,2, Jian Xiao2, Ping Qi2, Anhua Song2* and Zhen Huang1*
...h increased insecticidal activity in cell-free extracts that could potentially be used directly for insect control. 
...
Ying Liu1, Shankun Liu1, Hui Wang2 and Weihua Su2,*
...potent anti-inflammatory activity. The aim of the current study was to scrutinize the protective effect of caffeic acid against the streptozotocin induced GDM in rats and explores the possible mechanism of action. A total 36 female rats were caged into the male rats for the pregnancy, and 33 female pregnant rats were collected and weight. The female rats were group into following groups and each group contains 6 rats. Once the pregnancy was verified, the strep...
Eman A. Al-Shahari1,2, Abdelhalim A. Alkhazendar3, Eman R. ElBealy4 and Abeer A. Alm-Eldeen3*
...ic, that has antioxidant activity. Therefore, this study was performed to examine the possible role of quercetin in modulating aging-induced testicular damage. Samples from 30-months old rats’ testis were examined before and after 200 mg of quercetin/Kg administration. Before quercetin administration, they showed an increase in the lipid peroxidation and 8-hydroxy-2’-deoxyguanosine while showed a decrease in the superoxide dismutase
Iram Liaqat1*, Tahir Hussain1,2, Aisha Waheed Qurashi3, Gulbeena Saleem2Asia Bibi4, Muhammad Fiaz Qamar5,ShaukatAli1 and Ikram-ul-Haq6 
Riffat Sultana1*, Nuzhat Soomro2, Santosh Kumar3 and Ahmed Ali Samajo2
...amined that reproductive activity of Oxyinae was at its maximum in August to December. Mating duration has also been identified as a pest control method in which the insect does not become resistant.
...
Tasneem Shah*, Muhammad Tariq and Dost Muhammad
...r promotion of microbial activity in the soil. The low net N mineralization in the high biochar treatment implies that biochar could be used as a strategy to minimize N losses from the easily available labile N pools through greater N retention in soil.
...
Saad A. Moussa1, Mohammed Ahmed Mahmoud Abdullah2*, Mahmoud Saied1, Mustafa Saleh1, Mohamed A. Soliman2 and Ali Mahmoud Zanaty2
...showed haemagglutination activity by using 1% RBCs and also haemagglutination inhibition in case of using NDV reference antiserum, As well as realtime polymerase chain reaction by using standardized NDV specific primers and finally eight viruses were selected for further sequencing for the partial fusion protein, The eight NDVs isolates of velogenic genotype VII and contain the unique cleavage site motif 112RRQKRF117 with high relation to very virulent NDV Chi...
Simeen Mansoor, Jabeen Farheen* and Meher Hassan
 

...ved growth and increased activity of APX, CAT, and GPX as to control and lethal-temperature treatments. The total soluble protein profile showed highly significant variations and was broadly divided into two major clusters. The 116, 113, 109, 106, 94, 86, 76, 62, and 61 kDa fractions were identified the first time, which may be involved in temperature stress acclimation. Conclusively, the sublethal-temperature along with phytohormones are involved in gree...
Rukhsar Ali* and Ali Muhammad
 

...otal sugars, antioxidant activity, Vitamin C content) and sensory evaluation as color, taste, and overall acceptability stored at ambient conditions (25±2â°C) for six months with twenty days interval. Based on sensory analysis, the best suitable blend was selected within different ratios of mango pulp and loquat pulp. The blended pulp with ratio (60:40) got the highest mean score of judges for overall acceptability which used for further study. The dif...
Khaliq Dad1, Muhammad Nawaz2*, Rumsha Hassan2, Kainat Javed2, Asma Shaheen2, Fengliang Zhao3, Muhammad Imran4, Syed Tansir Hussain Shah4, Muhammad Faraz Anwar5 and Muhammad Aurangzaib6
 
...Cd contaminated soil and activity of biochar in the contaminated soil. In this study different treatments of Cd were applied in the presence of certain portion of biochar. The order of treatments was 0 mg Cd as control with biochar (12%), low Cd (10mg), high Cd (15mg), low cadmium + biochar (10mg+12%) and high cadmium + biochar (15mg+12%) with distilled water as control. Growth and physiological parameters of plant were studied and prominent results were obser...
Aneeqa Saleem1, Muhammad Islam1, Hamid Saeed1* and Mehwish Iqtedar2
...ficant anti-urolithiatic activity as evident from serum creatinine, uric acid and BUN levels.
...
Xinjian Wang1,2, Eryan Yang1,2 and Lizhi Zhou1,2*
... and habitat loss. Daily activity rhythm, time budget and foraging pattern of wintering swans are the important presentation of behavioral strategy in response to habitat variations. We studied the behavior of Tundra Swan wintering in the wetland of Huangpi Lake from November 2012 to February 2013. Wintering individuals and water levels were surveyed every day. Instantaneous scan and focal animal sampling was conducted to collect the behavior data. Foraging be...

Ali Ahmad1*, Zubair Aslam1, Korkmaz Bellitürk2, Naeem Iqbal3, Muhammad Idrees3, Muhammad Nawaz4, Muhammad Yasir Nawaz5, Muhammad Kashif Munir6, Ahmad Kamal1, Ehsan Ullah1, Muhammad Ahsan Jamil1, Yousuf Akram1, Tanveer Abbas1 and Muhammad Mohsin Aziz1

...ding capacity, microbial activity, superior in nutrient status and buffering capacity therefore having the amiable required physiochemical charms for fertility of soil and growth of plant. The worms increase the biological decomposition of organic substrates by maintaining the aerobic conditions of the organic substrates. Experiments on earthworms and the vermicast production by different species are also included in review. The paper also reveals fitness or c...
Saba Afzal1, Sohail Raza1,*, Masood Rabbani1, Sehrish Firyal2, Imran Altaf1 and Zahra Naeem1
...MTT assay. The antiviral activity of ivermectin was determined using viral inhibition assays and median tissue culture infectious dose (TCID50). The results showed that 2.5 µM concentration of the ivermectin is non-toxic to the Vero cells. At this concentration, PPRV titre was significantly reduced (p < 0.001) by two log to 103.0 TCID50/0.1 mL as compared to virus control 105.5 TCID50/0.1 m...
Yawang Sun, Yongjiang Wu, Jingbo Chen, Zili Wang, Juncai Chen, You Yang and Guozhong Dong*
...idant capability and the activity of superoxide dismutase (SOD) increased with increasing LPS concentrations. Gene expression of antioxidants including SOD, NADPH-quinone oxidoreductase 1, and hemeoxygenase 1 were significantly increased at the LPS concentrations of 12.5 and 100 ng/mL. Both Fanconi Anemia complementation group D2 protein and Fanconi Anemia complementation group L had significantly higher gene expression at 100 ng/mL LPS level. The protein expr...
Jen-Hong Chu1, Ya-Wen Lan2, Shyn-Shin Sheen3 and Angela Chien3*
...% of total lipid. Lipase activity in soft body increased with an increasing dietary lipid level, but amylase activity was not significantly affected by the dietary lipid level. Based on a broken-line of the final weight of L. canarium larvae, the optimum dietary lipid levels were 5.6%.
...

Qaiser Shakeel1*, Rabia Tahir Bajwa1­, Yasir Iftikhar2, Mustansar Mubeen2, Muhammad Luqman3, Waqas Ashraf1 and Ifrah Rashid4

...ermination of antifungal activity against Penicillium digitatum, a plant pathogenic fungi responsible for ginger soft rot. Petri dish were used to conduct bioassay through poisoned food technique with triplicates. The crude extract of all the plants showed a better inhibitory effects on the pathogen’s (P. digitatum) mycelial growth rather than fungicides. Among all the plant extracts, the best result was showed by garlic extract with 87% of mycelial grow...

Muhamamd Rizwan1*, Muhammad Arshad2, Muhammad Kashif3, Aneela Zameer Durrani4, Asghar Abbas5, Tanveer Ahmad6, Muhammad Nadeem7 , Kinza Khan8

...ystem by suppressing the activity of their immune receptors e.g. TLR. CRISPR Cas system also help bacteria to attach with the host body and replicate with in host body. It can develop antibiotic resistance in pathogenic bacteria, enhance their pathogenicity and can survival in host body. 
 
Novelty Statement | CRISPR Cas system is an integral part of prokaryotic immune system that provides protecti...

Saima Maher1,3*, Shahina Fayyaz2, Nadra Naheed3 and Zarbakth Dar1

...ermine their nematicidal activity against Meloidogyne incognita (the root-knot nematode). The seven pure bioactive compounds have been isolated and examined, from which VA 4 and VA7 had a potential effect against M. incognita by showing 90% mortality at 0.1 g/mL after 48 hours of exposure. The LC50 0.0149, 0.1575 μg/ml of (VA4 and VA7), respectively found to be significantly effective than compounds VA5 (LC50 = 0.1575 μg/ml), VA 6 (LC50 =0.1575 μg/ml)...
Zhi Wang1*, Wenhua Liu2 and FadaoTai3
...es. Still, its circadian activity patterns and time budgets in different behaviors remain unclear. Using artificial population of the animal bred in a simulated natural environment, activity patterns and time budgets were investigated. The results showed that the species was clearly nocturnal but varied greatly in the number of daily activity bouts showing bimodal patterns in winter, trimo...
Xiangzu Wang,1,2 Jifeng Xi,1,2 Bin Jia,1,* Yongsheng Zhang,1 Chaocheng Li1
..., the cell proliferation activity decreased, and the expression of ZFX, Bcl-2, and BAX were down regulated. The ZFX gene may participate in the developmental process of the kidney through the balance of cell proliferation and apoptosis regulation.
...

Sami Ul Haq1, Abid Hussain1*, Umair Riaz2, Muhammad Baqir Hussain1, Adnan Fareed1, Nabeel Ahmad Ikram3 and Fahim Nawaz3

Muhammad Shahzad1*, Syed Amer Mahmood2, Athar Ashraf3, Amer Masood2 and Saira Batool4

... exposed the neotectonic activity preserved in the Quaternary era in the surroundings of NPS. The TSR maps revealed that North-North-East (NNE), North-West (NW), South-West (SW) f the investigation region and segments parallel to the Sassi Raikot Fault (SRF), Sassi-Jaglot-Bunji (SJB) sector of Nanga Parbat Syntaxis as active tectonic zones. The areas which include, Shawar, Haramosh, Kachura, Astak Nala, Gilgit, Skardu, Astore, Sai Nala Jaglot, Gunar and Goriko...
Asmaa A.M. Abd El-Ghani *; Ahmed B.M.; Abdel-Raouf A. ; Nagwa S. Ata* and H.A. Hussein
... antiviral and cytotoxic activity of etanolic extract of Salvadora persica(L.)
roots was investigated on bovine herpes-1 (BHV-1) infection in vitro. An ethanolic
extract of Salvadora persica was used in two concentrations. MDBK cells grown on
Minimum Essential Medium (MEM) were used for virus propagation and titration. The
effects of two concentrations of Salvadora persica on viral growth in MDBK cells as
...

Mai A. Kilany1; Hanaa H.A. Gomaa1; Yousry E. Abo El-magd2 and Nermin Raafat2.

... RT-PCR were done. MnSOD activity was evaluated using a superoxide dis-mutase assay kit. Genotyping was performed by polymerase chain reaction and re-striction fragment length polymorphism (PCR-RFLP) method. The homozygous Ala/Ala (CC) was significantly more frequent in HCV-related HCC patients com-pared to HCV-infected patients and control group (67.5%, 12%, and 15% respective-ly, p Ë‚ 0.05). Moreover, the C allele was more often associated with HCV-related H...

Samah A. Mokbel, Ahmed K. El-Attar

... with different survival activity. The presence of phytoplasma 16Sr
DNA was examined using PCR detection before and after treatments. The different
treatments of radiation resulted in different survival rates and phytotoxic effects
including leaf yellowing and lack of growth. The 5Gy dose was proved to be best
effective dose for controlling the phytoplasma without affecting the in vitro growth
and sur...

Hanaa H. A. Gomaa1; Entsar A. A. Nassar2; K. A. El-Dougdoug3

...stle that have antiviral activity with different degrees, line 32 with (HAV), line 9 with (COXB4) and, line 28 with (HSV1).

...

Samah A. Mokbel, Soad H. Taha, Mahmoud M. Abd-El Hamid, Ali H. Hamed

...so, results of antiviral activity of lactoferrin at concentration 1000 mg/L showed great potential as phytotherapeutic source to produce quality and health plantlets for rapid and large scale in vitro production.

...

Lala Rukh1, Muhammad Nadeem1, Tusneem Kausar1, Mian Anjum Murtaza1, Muhammad Luqman2*, Muhammad Bilal Shahid1 and Amal Shaukat3

...al antioxidants and DPPH activity in soy date bars however, decreasing trend was observed in total antioxidants and inhibition of DPPH radical activity during 90 days of storage. Based on the results, it has been suggested that date bars may be considered as a source to meet the energy requirements of health-conscious consumers. Moreover, date pit powder and soy protein isolate can be used as nutraceutical in different funct...

Dina N. Abd-Elshafy

...investigate the anti-HAV activity
of the green tea extract according to Tebas (1995), evaluate its effect, to test effect of
applying green tea extract against contaminated drinking water with HAV and study stability
of inhibitory effect of extract on HAV in water.
Results: Green tea extract has a strong anti-HAV effect with direct effect on the viral
particles. Supplementing tap water with the extrac...
Zain-Ul-Aabdin Abro1*,Naheed Baloch1, Raza Muhammad Memon2 and Niaz Hussain Khuhro2
...enhances the fruit flies activity in connection with the availability of fruiting parts. The present investigations would be helpful to attain effective integrated pest management campaign in guava orchards.
...
Nehafta Bibi1,2, Faiq Jan3, Munawar Saleem Ahmad4 and Haitao Wang1,5,*
...t intensity threshold of activity in two groups of passerines, i.e. secondary cavity and non-cavity nesting. For this purpose, different species of secondary cavity and non-cavity nesting passerines were subjected to two phases of trials: in the first trial birds were released in an experimental cage and allowed them to accommodate themselves in darkness for 10 min. In the second trial we turned on the dimmer to a given luminance for 2 min. We...

Aliya Munir1, Sajid Abdullah1*, Huma Naz2*, Khalid Abbas1, Tanveer Ahmed3 and Zahid Farooq2

...ted to calculate the POx activity. It was observed that the exposure of DM+ES significantly accelerated the POx level in gills, liver and kidney of fish in a time dependent manner.  

...

Ibadullah Jan1*, Iqbal Munir2, Inamullah Khan3, Syed Muhammad Suhail4 and Aqib Iqbal2

...nt (p<0.05) analgesic activity with anti-nociceptive effect in hot plate test in a dose-dependent manner. Dosiflavone showed significant anti-nociceptive activity and decreased the number of writhes instigated by one % ethanoic acid. Dosiflavone dosages (20, 40, and 80 mg/kg) were relative to the placebo, there was a substantial (p<0.05-0.01) reduction in pyrexia. The Dosiflavone-treated and control groups showed no si...
Bingjie Zhou1, Hitesh Bhagavanbhai Mangukiya1, Siva Bharath Merugu1, Fakhar-un-Nisa Yunus1, Yuchen Fan1, Zhenghua Wu1,* and Dawei Li1,2,*
...y chromatography. The bioactivity of AGR2 was tested by cell proliferation and wound healing assays, while the auto-fluorescent property of DsRed was confirmed by fluorescence microscopy and immunofluorescence. The potential application of his-AGR2-DsRed was demonstrated by its internalization in fibroblasts. Therefore, the purified recombinant fluorescent protein would be a very useful tool for further investigation of AGR2’s extracellular function and ...

Dilan Ozmen Ozgun1, Gonca Alak2, Arzu Ucar2, Sinan Bilginer3, Halise Inci Gul3, Mahmut Kocaman2, Cem Yamalı3, Veysel Parlak2, Muhammed Atamanalp2, Ahmad Maslat4 and Telat Yanık2*

...ed to control group. SOD activity was time dependent; it decreased initially, but then take increased. WBC, MCV, MCH and MCHC levels increased, while RBC Hb, Htc and PLT levels decreased with increasing dose from 0.25 to 2.5 mg/L of B4 (p<0.05) compared to control. There were no differences between control and DMSO group (p>0.05) with respect to all tested properties. It is suggested that B4 should be investigated further for possible usage in aquacultur...
Wenjuan Yan1, Qunlan Zhou2, Bo Liu2,3*, Cunxin Sun2, Huimin Zhang3 and Changyou Song2
...tly increased plasma ALT activity, urea nitrogen, total protein, albumin and globulin contents, while significantly decreased AST activity in 400 mg Kg-1 group. Haemolymph SOD and GSH-PX activity was enhanced significantly in 400 and 800 mg Kg-1 group, respectively, while MDA content was significantly decrease in these two groups. I. cicadae did not affect the ...
Zhengyi Fu1,2,3,4, Rui Yang2,3,4, Zhenhua Ma2,3,4*, Mingyang Han2,3,4 and Yifu Wang2,3,4
... and digestive enzymatic activity of barramundi (Lates calcarifer). Fish were fed ioso engery diets (18 kJ/g) with two types of non-protein energy sources in the experimental groups and a regular diet was used as the control. The feeding trial lasted for 56 days. Results from the present study indicate that, except for weight gain and feed intake, most growth parameters of fish were not significantly affected by the experimental diets (P > 0.0...
HuaBin Zhang1,2, YaSen Li1, Tao Pan1, Peng Yan1, En Li1, Hui Xue1 and XiaoBing Wu1,*
...ults showed that immunoreactivity of leptin was observed in the adipocyte of white adipose tissue, the gastric gland of the stomach, the lamina propria of the intestine and the interstitial cell and seminiferous tubule of testis, leptin receptor staining was detected in the adipocyte of white adipose tissue, the gastric gland and submucosa of the stomach, the submucosa, muscular layer and intestine villi of the intestine, the granulose cell and follicular memb...
Hui Wang1,2, Yuchen Zhao1 and Xinpu Wang1,*
...relationship between the activity-density of carabid beetles and environmental factors was conducted under three different grassland management regimes (typical enclosure, enclosed mowing, and farmer grazing practice) in the Ningxia Hui Autonomous Region, northwestern China, from May to September 2017. Eighteen species from nine genera were collected in all regimes. The largest size of species and individuals occurred in mid-August, and species diversity and a...
Mengke Wang1, Shucheng Huang2, Cai Zhang1*, Haizhou Gong1
Shunan Cuan1, Shuaishuai Wang1, Qi Shao1, Wenhao Xu1, Sudan Meng1
Pengfei Li1, Yuqin Wang1 and Zijun Yang1
...nificantly decreased the activity of alanine aminotransferase (ALT) (p<0.05), the content of total protein (TP), albumin (ALB) and globulin (GLB) (p<0.05). Furthermore, supplementation of MAG increased the activity of total superoxide dismutase (T-SOD) (p<0.05), slightly increased the activities of total antioxidant capacity (T-AOC) (p>0.05) and catalase (CAT) (p>0.05). And the concentrations of malondialdehyd...
Jia Li and Hong Yang*
...Therefore, the microbial activity also engaged in the biodegradation of BaA like genes quantity, the activity of enzymes and functional of bacteria, were also increased due to the APG and alkaline treatments. Overall, the instantaneous enhancement of microbial activity and BaA bioavailability increased biodegradation efficiency.
...

Ayesha Gul1, Mohammad Sayyar Khan1*, Mazhar Ullah1 and Iqbal Munir3

...tent i.e. (5%). Catalase activity was not significantly different between control and the stressed calli after 30 days at all PEG %. However, the catalase activity was significantly increased (0.14 µMole ml-1 min-1) as compared to that of the control (0.06 µMole ml-1 min-1) at 7.5% PEG media after 60 days of stress application. PEG stress showed a significant increase in proline content. Control calli showed less...
Mona Mohammed EL-Derbawy1, Eman Naser Hafez2*, 
Mona Abdel Daym Abd Rabbo1, Nagwa Ibrahim Toaleb3,
 Saedia Abdel Hady Sayed El-Ahl1 and Bahaa Eldkeen Wade EL-Aswad4 
...icity due to low cross-reactivity with other parasites. S0 it can be used as a tool for diagnosis of chronic schistosomiasis.
...
Jun-Dong Tian1,2, Wei-Jie Guo1,2, Han Yan1, Jie Zhang1, Shu-Liao Tian3 and Ji-Qi Lu1,2,*
...y many factors including activity rhythm which responds to the timing of feces defecation. To test the effect of activity rhythm on fecal microbiota, we used non-invasive sampling method to collect the feces defecated in the morning (AM group) and afternoon (PM group) from a zoo rhesus macaque population. Then 16S rRNA sequencing technology was adopted to assess the microbial communities. The results showed i) the dominant p...
Gong Xue-na1, Jia Ting2, Zhang Di2 and Zhu Wanlong1*
...ng metabolic rate (RMR), activity behavior, serum leptin levels, hypothalamic neuropeptide expressions and body compositions were measured. The results showed that regions and HF diet affected body mass, food intake and RMR significantly, HF diet increased body mass in E. miletus, while regions had significant effect on activity behavior, but HF diet had not affect activity behavior...
Muhammad Zohaib1, Muhammad Sajjad Ansari1*, Bushra Allah Rakha2* and Ali Akhter2
...the study area; breeding activity was observed in 51 active nests. The successful nests for breeding activity were recorded in parks (46%) followed by orchards (28%) and agricultural fields (27%). Highest percentage of successful nests was found on forks (48%) while nests on middle, terminal and other positions of plants were recorded as 17%, 10% and 25%, respectively. The preferred height for nest construction was recorded ...

Salma Javed1* and Daniyal Siddiq2

... increasing. Nematicidal activity of “Black plum Syzygium cumini, leaf aqueous, ethanol and methanol extracts were investigated for managing the population of Meloidogyne javanica, in tomato. In laboratory conditions second-stage juveniles (J2) mortality was recorded after 24, 48 and 72 h of incubation in concentrations of 0.25, 0.5 or 1%. Maximum mortality was achieved with ethanol extracts followed by aqueous and methanol extracts. In the greenhouse, l...

Asma Hanif* and Shahnaz Dawar

...to screen the vermicidal activity of various homeopathic medicines at 100, 75 and 50% v/v concentrations of different potencies including mother tincture (Q), 200C and 30C against root-knot nematode Meloidogyne javanica using hatching and mortality test at different time intervals. Notable results were noticed by Kent-20 and Santonine-43 at all tested concentrations by reducing the hatching and complete mortality of M. javanica after 96 hours, while Cina (Q) s...
Congfen Zhang1,Yingxiao Liu2, Linfeng He2, Fengjun Shi2, Weitang Yao2 and Xuegang Luo2,*
...ted and the trend of SOD activity changes was down-regulation in a time-dependent manner with higher concentration treatments. The changing trends in the mRNA levels of these enzymes were not always consistent with those of enzymatic activities. The fat body of A. pernyi, as an important antioxidant tissue, can increase the expression of oxido-reductas system enzymes by promoting the expression of SOD, CAT, GST and glutathione peroxidase (GSH-Px) to imp...

Muhammad Shahbaz1,2, Sajid Abdullah1*, Huma Naz3*, Khalid Abbas1, Tanveer Ahmed4, Sana Mehmood1, Muhammad Adeel Hussan5

...luate the catalase (CAT) activity in Ctenopharyngodon idella fed with vitamin E (VE) supplemented diet. Four different diets viz. T1 (VE-0 mg/Kg Control), T2 (VE-200 mg/Kg), T3 (VE-350 mg/Kg) and T4 (VE-500 mg/Kg) were prepared containing different levels of VE. The C. idella was fed @ 3% of body weight three times in a day for 30 days. At the end of trail fish was dissected and tissues viz. liver, muscle and gills were obtained to analyze the CAT

Yaregal Tilahun1*, Benyam Tadesse1, Getachew Mekonnen2  and Tilahun Bekele3

...s production and selling activity in the research area. The Cobb Douglas model indicated that labor force, fertilizer, land size, and improved seed all had an impact on tea productivity. While, technical inefficiency of tea production was determined by to level of education, the interaction of extension contact, distance to district market, harvesting time, training, and participation to off/non-farm income. So, improving the skill and knowledge of farmers thr...
Sadaf Ashraf1, Masood Ahmed Siddiqui1*, Kanwal Nisa1, Samar Ali1 and Naeem Rashid2
... optimal α-amylase activity at 85°C and pH 5.5. The activity was not dependent on any metal ion. The hyperthermophilic nature and metal ion independence make it a suitable candidate for both basic as well as applied research.
...
Syed Shahid Imran Bukhari1*, Nusrat Jahan2, Muhammad Khalil Ahmed Khan3, Mariam Zaheer1, Sabir Javed1
...c and antihyperlipidemic activity, this study was aimed to check efficacy and toxic limits of different doses of gel extract in diabetic induced albino mice. Male albino mice, weighing (25±5g) were divided into three groups; Group 1: normal (non diabetic nontreated), Group 2: diabetic non treated (DNT), Group 3: diabetic treated (DT) mice. Group 3 was treated with three doses of A. barbadensis (200 mg/kg, 300 mg/kg and 400 mg/kg) per day for 14 days wer...

Najeeb Ullah1*, Muhammad Nadeem2, Malik Mujaddad-ur-Rehman1, Rubina Nelofer2 and Yasir Arfat3

...period. Maximum protease activity was observed by using molasses (540.62 ± 26.77 IU/ml) as carbon source and NaNO3 (606.95 ± 7.61 IU/ml) as nitrogen source. The optimum conditions predicted by RSM were substrate 2%, molasses 1.5%, temperature 35 °C, pH 9.0 and induction period of 96 hour. Almost 2.9 fold increase in protease production was observed after optimization at these optimal conditions. All these results indicated that skin waste fro...

Ayesha Muzamil, Hafiz Muhammad Tahir, Shaukat Ali, Iram Liaqat, Aamir Ali, Muhammad Summer

...metabolic reactions. The activity of various leukocytes is suppressed by IL-4 and IL-10 (anti-inflammatory cytokines) that triggers the production of pro-inflammatory cytokines. This review paper provides an overview of inflammation, its associated factors, causes and treatment and role of cytokines in inflammation. 
 
Novelty Statement | This review article provides an overview of sericulture acti...
Amr N. El-Shahat1, Refaat G. Hamza1,*, Ashraf M. Mounir1 and Madeha N. Al-Seeni2
...ric acid, glucose level, activity of some liver enzymes and liver and kidney TBARS levels with remarkable increases in level of HDL-C, insulin and showing elevation in GSH level and SOD and CAT activities of the liver and kidney of gamma-irradiated treated rats compared to irradiated group.It was suggested that the biochemical and antioxidant amelioration observed in GFJ treated irradiated rats might be due to the an...

Vladimir Safonov 

...anifested in the reduced activity of glutathione peroxidase and glutathione reductase. The consumption of Vitamin E as a non-enzymatic element within the antioxidant defense system increased significantly by up to 2.27 times. Study results of the blood biochemical composition show that selenium deficiency may facilitate the development of pathologies in the liver and excretory system . Therefore, food additives as an additional source of micronutrients may be ...
Noor Bad Shah Khattak1, Hamayun Khan1, Muhammad Tarique Tunio2, Shakoor Ahmad1, Nazir Ahmad3, Syed Murtaza Hassan Andrabi4, Obaidullah5, Ihsan Ali1,5,* and Nan-Zhu Fang5,*
... describes antioxidative activity of green tea (GT) extract on standard post-thawed quality indicators of frozen buffalo bull’s spermatozoa. Semen samples were obtained from the bulls for three weeks through artificial vagina. Egg yolk was used as an extender, in which different concentrations of GT extract (0.0%, 0.50%, 1.0%, 1.5%, 2.0% and 2.5%) were added. Semen quality indicators studied were the percentage of motility, survivability, plasma membrane...

Noha M. El-Shabrawy1, Atef M. Kamel2, Aza S. Goda1, Gehad R. Donia1, Ahmed M. Salah-Eldein2* 

...xtensive growth of human activity, urbanization, agricultural and industrial processes result in increasing the number of pollutants introduced into the environment. Continuous monitoring of such pollutants required an indicator sensitive to environmental toxins and represents its accumulative effect. The aim of the present study is to determine the preferable tissue and bird that can be used as a bio-indicator for heavy metals pollution in El-Salam Canal whic...

Faryal Malik, Mudassar Nawaz Khan* and Israr-ud-Din

...during the recovery. CAT activity in Atta Habib was raised from 1.63 under flooding stress to 2.32 unit/mg protein at the end recovery period. SOD activity was increased from 2.27 to 3.15 unit/mg protein and POD from 1.71 to 2.39 unit/mg protein. The enzyme activities in Siran revealed the same trend as observed in Atta Habib. Recovery capacity was least in Ghanemat-e-IBGE. The results suggest that the tested three wheat var...
Shoaib Ahmed Pirzado1,2*, Wu Zhengke1, Adanan Purba1, Chen Jiang1, Huiyi Cai1, Chen Guilan1 and Guohua Liu1*
...lity, intestinal enzymes activity, immune function, and bone mineralization of broiler chickens. A total of 240-day old male chicks were randomly assigned into comprising four treatments with six replicates (n=10), which included control (basal diet), control +0.25% AZO, control + 0.50% AZO and control + kitasamycin (as AGPs). The results indicate that LBGW, ADG and FCR was significantly (P<0.05) improved in AZO 0.25% and 0.50% than the control. Eviscerated...

Ho Shi Hui1, Eng-Keng Seow2, Nurul Huda1* 

...d stability, emulsifying activity, tube inverting test, folding test, expressible moisture and texture profile analysis were compared. Ultrasound treatment had caused a significant (p<0.05) change in pH, foaming capacity, and the folding test score of egg white gel. However, texture profile analysis showed that the hardness, springiness, gumminess and chewiness of egg white gel had decreased after ultrasound treatment. Ultrasound-treated duck egg white for ...

Syed Sikandar Habib1*, Saira Naz2, Sehar Khalid3, Rimsha Kanwal2, Iqra Ameer1, Sadia Nawaz1 Aamir Khan4, Abid Ur Rehman5, Muqaddas Kousar6, Shafa Ullah Khan7 and Nadia Nazir7

...as shown higher lysozyme activity and ACH50 level, while no significant enhancement was observed in Ig. Beside this all the haematological parameters including WBC, RBC, Hb, Hct and differential leucocyte was observed higher in all the groups as compared to control group. It was concluded that 6% Agaricus bisporus can be use as immune-stimulant, and can help the farmers to overcome the emerging aquaculture problems.

...

Arkan B. Mohammed*, Ammar S. Abdulwahid, Samah M. Raouf 

...ndialdehyde, AST and ALT activity in comparison to the control. Therefore, it can be concluded that thyme additives can be used in laying hens diet to improve egg production, egg quality, antioxidant and biochemical parameters in a dose-dependent manner.

 

Keywords | Antioxidants, Egg production, Laying hens, Thyme
 

...
Elfadil Elfadul Babiker1, Khalid Ahmed Abdoun2*, Fahad AL Juhaimi1, Kashif Ghafoor1, Riyadh Salih Aljumaah2 and Ahmed Abrahim Al-Haidary2
... enhanced serum catalase activity by > 9% as a function of feeding period. Animals fed on Moringa-supplemented diets also showed reduced serum concentration of malondialdehyde (MDA) by > 45% compared with AHD-fed animals. Reductions in the serum concentrations of glucose by 14 to 41%, and that of cholesterol by 18 to 40% were observed in animals fed on Moringa-supplemented diets. It is worth mentioning that MOD supplementation showed the greatest positiv...

A.M. Abdul Azeem, Ashraf M. Mounir and Amr N. El-Shahat*

...hyde serum level and the activity of xanthine oxidase were elevated (P < 0.05) with obvious reduction in the concentration of insulin, total thyroid hormones triiodothyronin and thyroxine, leutinizing hormone, testosterone and testicular antioxidant parameters (glutathione content , the activity of xanthine dehydrogenase, superoxide dismutase and catalase) in the group of alloxan (150 mg/kg B.WT)-administrated rats as com...

Chunjie Song1, Shangquan Gan2 and Xiaoyun Shen1,3*

...The serum catalase (CAT) activity in the high-dose group was extremely significantly higher (P<0.01) than that in the low-dose group, gentamicin sulfate group, and control group. Consequently, modified Yujin powder had a good therapeutic effect on the E. coli in P. przewalskii, and the effect of the high-dose group was better.

...

Mirza Gul1*, Muhammad Zahid1, Ikram Ilahi2, Hazrat Ali2*, Fida Hussain3 and Muhammad Anwar Sajad3

...ration and mosquitocidal activity. Regarding predatory control, it was found that during a 12-hour laboratory study, A. cybister consumed 10 exposed larvae. Under field conditions, introduction of predator decreased the larval density from 141.7 to 71 in 15 days. In conclusion, these plants and predator may be useful in controlling mosquito populations in an eco-friendly way.

...
Johar Hussian1, Faiz Muhammad2, Shafqat Fatimah Rehmani3, Aqeel Ahmad4, Nazir Ahmad Lone4, Moomal Bughio5, Syed Khurram Freed1 and Shakeel Ahmed Khan4*
...en were readily lost its activity from 7 log2 to 2 log2 after two months of incubation. During specificity test all antigens showed specific effect on IBV by eliciting agglutination of RBCs while other avian viruses avian influenza (AI), new castle disease virus (NDV) and infectious bursal disease virus (IBDV) were not affected by enzymatic inductions. Therefore, the antigen prepared by phospholipase C has been found to be more effective for HI test for rapid ...

Fulencio Ferretiz-Rodríguez1, Jose Alejandro Roque-Jiménez1, Héctor A. Lee-Rangel1*, Gregorio Alvarez-Fuentes1, Juan Carlos Garcia-Lopez1, Rolando Rojo-Rubio2 

...n. Aspartate transferase activity decrease (P ≤ 0.05) with BIO supplementation. Results indicate that the herbal BIO and OP present some productive and metabolic changes.

Keywords | Dairy cows, Choline, Methionine, Herbal formulas, Phytogenic sources 

...

Lanjie Li1, Jingjing Zhang2, Ruiyan Zhang2, Ning Zhang2, Zixiang Wei2, Guiqin Liu1,*, Riaz Hussain Pasha3, Muhammad Akram Khan4 and Saif-Ur-Rehman5

...composition, antioxidant activity, and molecular weight distribution of oligopeptides in hydrolysates were studied. The optimum enzymatic hydrolysis conditions were identified at 5.96 pH, 0.7% enzyme-substrate ratio, 55ºC temperature and 3 h time. Under these optimum conditions, DH of 25.4%, PR of 95% was obtained. Moreover, hydrolysates were rich in oligopeptides, especially di- and tri-peptides and demonstrated good antioxidant activities. These results...

Juliet N. Ozioko1, Obinna V. Ayogu2, Benjamin O. Ezema1, Dilibe C. Uramah3 and Kingsley O. Omeje*,1

...t changes in their serum activity. Similarly, superoxide dismutase and catalase showed no significant increase after the period of study.

...
Damat Damat1*, Roy Hendroko Setyobudi2, Juris Burlakovs3, Zane VincÄ“viÄa-Gaile4
Devi Dwi Siskawardani1, Rista Anggriani1 and Anas Tain5
...rotein, fat, antioxidant activity, fiber content, water absorption index, color intensity, and sensory evaluation. The data were analyzed by ANOVA and continued according to Duncan’s multiple range test. The results showed that all formulas of analog rice produced from arrowroot starch, with the addition of seaweed pulp and spices, fulfill the chemical and physical properties of paddy rice requirements according to Indonesian National Standard No. 6128-2...

Alexander Tsybulsky1*, Tatyana Tabakaeva1, Anna Klimovich2, Michail Shchelkanov1, Eduard Kostetsky1, Maksim Aliev1, Anton Degtyarenko3 

...plicative and expressive activity of FeLV evaluation in the infected organism cells, innate immune factors for antivirals evaluation, interferon system (IFN) in particular, molecular guard factors for cell genome integrity evaluation (p53, etc.). Methods. In domestic cats with a previously established diagnosis of «FeLV-infection and chronic leukaemia» (n = 10) and healthy control cats (n = 6), we examined the following: 1) Haematological parameter...

Neda Amani1, Mehrdad Shariati1, Rahim Ahmadi2,3*, Mokhtar Mokhtari1 and Saeed Khatamsaz1

...ime PCR and the caspases activity was measured by ELYSA method. Flow cytometry was used to detect and quantify the level of apoptosis in cell lines. The data were statistically analyzed between groups using ANOVA and student’s t-test. Decreased viability was observed in AGS and HCT cells exposed to 0.1 and 1 mg/ml of testosterone. Exposure of AGS and HCT cells to cytotoxic dose of testosterone enanthate led to significant increase in gene expression and ...

Hung Van Mai1, Tuan Duc Nguyen2, Nang Thu Tran Thi3 and Hung Phuc Nguyen4*

...A) concentration, lipase activity, and lipid apparent digestibility coefficient (ADC) in pompano. The FSBM1 was produced by fermentation of defatted soybean meal (SBM) with Bacillus subtilis B3. The FSBM2 and FSBM3 were commercially available products, which were produced by fermentation of SBM with Lactobacillus spp. Five diets were formulated and denoted as FMD (fish meal-based diet), SBMD (SBM-based diet), FSBM1D (FSBM1-based diet), FSBM2D (FSBM2-based diet...

Saydat Saad1, Doaa Abdel-Fattah1, Tarek Khamis2, Aya El-Sobky1* 

..., indicating increased reactivity and solubility. Nanotechnology has a huge potential to make a major change in the agriculture and livestock sector. It can introduce new tools for molecular and cellular biology, biotechnology, veterinary physiology, animal genetics, and reproduction. Nano-propolis is beneficial to veterinary medicine in different aspects by varying the size of propolis using various techniques, nano-propolis can be more effective without comp...

Amir Z. Allam, Hayam A. Mansour, Nermeen M.L. Malak, Heba H.S. Abdel-Naeem* 

...oved their antibacterial activity. Furthermore, treatment of chicken patties with TCL, TO, OCL, as well as TOCL completely suppressed the growth of LAB (< 2 log10 CFU/g) at 0-time of examination and during the entire freezing storage. Additionally, the highest reduction rate in APC, psychrotrophic, and Enterobacteriaceae count was observed in samples treated with mixtures of three oleoresins (T-CL-O) as compared with other groups. In conclusion, the food in...

Hams M.A. Mohamed1, Mona A. El-Zamkan2* 

... expressed a proteolytic activity. It was thought that S. thoraltensis is non-pathogenic in humans, however, recently, it was implicated in many infections and its isolation from raw milk represents a potential risk for human health. According to our best efforts of research, it is the first time to isolate S. thoraltensis from raw milk in Egypt.

Keywords | Raw milk, Streptococcus thoraltensis, Antimicrobial resistance, Biofilm production, Proteolytic ...

Syed Haseeb Ahmed Shah, Irfan Shahzad Sheikh, Abdul Samad, Muhammad Kamran Taj, Mohammad Masood Tariq*, Majed Rafeeq, Sumaira Fazal, Niamatullah Kakar, Sabeera Afzal and Asadullah

...l cellular and metabolic activity which results in impaired growth or death of these bacteria. This study was planned to find out the effect of AGPs in broiler chicken. For the purpose one day old (n=432) broiler chicks were used in the experiment. Nine groups comprising of 48 chicks with 3 replicates of sixteen broiler chicks each were formed for the trial. Control group was kept on basal diet. AGPs (Oxytetracycline and Tylosin phosphate) were supplemented so...

Hafiz Adnan Ahmad1,2*, Muhammad Aslam2, Salman Gul2, Tariq Mehmood2 and Munawar Ali Munawar2

...omethacin. The structure-activity relationship (SAR) was also discussed with the reference of substituent nature. Present results showed that newly synthesized hybrids have significant anti-inflammatory potential and might be played an important role to the development of more potent anti-inflammation agents in future. 

...

Ramy S. Yehia1,3, Essam A. Shaalan2* and Hashem M. Al-Sheikh1 

...pliae in both larvicidal activity and inhibition of flies’ emergence. Blends from fungi and essential oils exhibited synergistic effect but fungi mixture produced antagonistic effect. The development of M. domestica larvae was affected by sublethal dose from fungi. In conclusion, M. anisopliae is more efficient than B. bassiana and could be easily mixed with essential oils to either enhance larvicidal activity or utili...

 Hanan Fathy Hammouda1, Mohammad Mahmoud Farag2*, Mervet M.F. El Deftar3, Mohamed Abdel-Gabbar4, Basant M. Mohamed4

...lular in vitro bioactivity test was performed in simulated body fluids for periods 1, 3, 10, 20 and 30 d by measuring the calcium and phosphate ion concentrations by SEM/EDX analysis. While, the bioactivity of expanded and differentiated osteoblast cells derived from isolated rBM-MSCs by flowcytometric analysis was studied by histochemical staining with Alizarin Red and von Kossa to confirm the osteogenic differentiat...

Ali Ghazi Atiyah1*, Nadia Hameed Rija Al-Falahi2 and Ghazi Atiya Zarraq3

... using SBF showed the bioactivity of the scaffold. Finally, the β-CPP scaffold was successfully synthesized from avian eggshell waste with high purity and favourite biocompatibility which was promising for use as bone substitution materials.

...

Qaisra Siddique1*, Sajid Abdullah1, Huma Naz2, Khalid Abbas1, Laiba Shafique1 and Qingyou Liu3

...ione S-transferase (GST) activity and total protein contents in various tissues (gills, hepatic, renal, brain, muscle and cardiac) of Labeo rohita was determined. Fish was exposed for 60-day and sampling was done after 7-day. Results showed that the GST activity was considerably increased in L. rohita as compared to control. The GST activity was enhanced in various tissues (hepatic, brain,...

Nuzhat Naseem, Sajid Abdullah and Sana Aziz*

...ause there is no phytase activity in agestric fish. This study was performed to determine the impact on proximate composition of whole-body of Labeo rohita (fingerlings) fed distiller’s dried grains with solubles based diet, supplemented with phytase. Six different feeds were formulated by supplementing different concentrations of phytase. i.e. D1 without phytase supplementation, D2, D3, D4, D5 and D6 with 250, 500, 750, 1000 and 1250 FTU phytase per kil...

Hafiza Mehwish Iqbal1, Qurrat Ul Ain Akbar1, Saqib Arif1, Shahid Yousaf2*, Salman Khurshid1, Saqib Jabbar2, Neelofar Hamid3 and Uzma Sitara1

...solids) TSS, antioxidant activity using 2, 2-diphenyl, 1-picryl hydrazyl (DPPH) and antimicrobial activity in Roma VF tomato variety was assessed within three different mature levels viz., green, pink and red. Outcomes from recent study pointed out that maturity levels involved to change the quality of tomato. Moisture and ash increased with the maturity ranged from 89.38±0.54 to 93.34±0.48 and 0.35±0.02...

Heba El-Zahar*, Zeinab Abd El-Rahman, Abbas El-Naggar 

...ignificant rise in serum activity of aspartate aminotransferase (p<0.05), and blood urea nitrogen, blood creatinine, lipase and alkaline phosphatase (p<0.01) in IBD dogs. The mean values of IBD-related biomarkers (CRP, haptoglobin, and fecal calprotectin concentrations) increased significantly (p<0.05 or p<0.01) compared to controls. CRP, haptoglobin concentrations, and fecal calprotectin were found to have a strong positive correlation. Furthermor...

Mohamed Abd El-Fattah Abo-Farw1, Maged Ahmed Aboul-Omran1, Abdel-Khalek El-Sayed Abdel-Khalek2* 

...n of estrous and ovarian activity and decreased pregnancy rate, antioxidant status, thyroid and reproductive hormones and trace elements such as Zn and Se.

Keywords | Mastitis, Buffaloes, Pregnancy rate, Antioxidant, Trace elements. 

...
Mubashir Ali Rather1, Ambreen Hamadani2*, Syed Shanaz2, Nusrat Nabi2, Showkat Ahanger1, H. Hamadani2, Ruksana Shah2
...nant rearing is the core activity of the economically weaker sections in Jammu and Kashmir, India. The state has a rich diversity of sheep genetic resources. However, concerning wool traits, the production potential of these breeds was poor. Accordingly, crossbreeding was taken up the breeding policy to improve the genetic worth of these breeds. As a result, a fast-growing and fine wool-producing sheep strain Kashmir Merino was developed. The present article s...

Doaa Khairy1, Mohamed Ali Osman2 and Fatma Abdel Mohsen Mostafa1*

... The highest nematicidal activity was performed by leaf extracts mixture of moringa, neem and canola. NPK, chlorophyll Aand B, salicylic acid, phenols and phenylalinine enzyme (PAL) in tomato leaves were significantly (P<0.05) induced by plant extracts mixture. Phytochemical analysis of aqueous neem leaf extract demonstrated the occurrence of a number of flavonoids (21) and phenolic compounds (23) including Hespiridin, Naringin, Rosmarinic acid, Pyrogallol,...

Rana A. Ali1, Abd-Elraheim A. Elshater2, Heba A. Mohammed3*, Mahmoud Elshazly4 

... assess the hypoglycemic activity of the laser on diabetic experimental animals. Methods: The present work was carried out on 40 albino rats, and equally divided into 4 groups, (10 rats/group) as following: Group 1, animals served as control. Group 2, animals received STZ. Group3, animals received laser. Group 4, animals received STZ+ laser. After the experiment, blood samples were collected for biochemical analysis. Also, the pancreas was dissected for histo...

Mohamed Mohamady Ghanem1*, Yassine Mahmoud Abdelraoof1, Abdelghany Hefnawy Abdelghany2, Eman Abdelhamid El-Ebissy3, Ahmed Ragab Askar4,5, Attia Ahmed Eissa6  

... pH, protozoal count and activity. Ultrasonographically, there was significant increase (P < 0.05) in ruminal wall thickness, reticular wall thickness, and small intestine diameter. The content of abomasum and small intestine appeared more echoic. Treatment with Rumitone changed the clinical, hematological, and biochemical alterations toward the reference values. It was concluded that camels are prone to induction of lactic acidosis by sucrose that induced ...

Nuraini Nuraini*, Mirzah Mirzah, Yuliaty Shafan Nur, Harnentis Harnentis 

...eter measured: cellulase activity, crude fiber, fiber digestibility, crude protein, and nitrogen retention. The results of phase 1 showed that the types of fungi had a very significant effect (P <0.01) on the nutrient quality of fermented Azolla microphylla. Fermentation of Azolla microphylla with Lentinus edodes and Pleurotus ostreatus gave the best products. Phase 2. Application Fermented Azolla microphylla (AMF) in the diet on broiler performance. Ferme...

Min Li1, Shiwu Deng2*, Yiqian Peng3 and Hong Li2

...electron microscope. The activity of Caspase-3 in heart tissue of SD rats was measured, and the expression of p-JNK, GRP78, Caspase 12 and CHOP in heart tissue of SD rats was determined by Western blot. We found that LVEDd and LVESd in MIRI group and MIRI + DEX group were significantly higher than those in sham operation group (P<0.05), and LVEF was significantly lower than that in sham operation group (P<0.05). Compared with MIRI group, the expression l...

Lin Lu

... blotting. We found that activity of TPC-1 cells was inhibited by different concentrations of Polysaccharide from H. diffusa, which was time and concentration dependent (P<0.05). When TPC-1 cells were treated with polysaccharide of H. diffusa for 48 h, the apoptosis rate increased, the expression of Bcl-2, PI3K and p-AKT decreased, the expression of Cyt-C, Bax and cleaved caspase 3 increased significantly (P<0.05). LY294002 could significantly inhibit th...

Roshana Mukhtar1, Shaheen Shahzad1*, Sajid Rashid2, Maryam Rozi2, Madiha Rasheed3, Imran Afzal4 and Pakeeza Arzoo Shaiq5

...er caused by an abnormal activity of uroporphyrinogen-III synthase (UROS), aminolevulinic acid and GATA1 (GATA binding factor 1) genes. The fundamental genetic cause of CEP has been linked to a sequence variant of UROS on chromosome 10q252-q263. The enzyme catalyzes the fourth step of heme synthesis pathway. The present study focused on the clinical assessment of CEP affected individuals in a Pakistani consanguineous family by Sanger sequencing of UROS gene to...

Laiba Ajmal1, Sidra Ajmal2, Maleeha Ajmal3, Gul Nawaz3, Rabail Hassan Toor4, Hooria Younas1, Tassaduq Hussain Sheikh5 and Raazia Tasadduq1*

...rations in the modulated activity of HLA system influence the fetal tolerance. Therefore, this review will provide an insight on how the working of HLA at the maternal fetal interface contributes towards recurrent pregnancy losses (RPL). Antigen hiding is a phenomenon that contributes towards immune evasion by the fetal cells as the placental barrier lacks HLA expression. However, the HLA molecules that are expressed by the extravillous trophoblast modulate ma...

Luan Arthur Queiros Lima, Talita Monielly Alves de Oliveira, Thiara Guimarães Maia, Ayko Shimabukuro, Itainara Taili, Raul dos Santos and Cecilia Calabuig*

...record the predation and activity of the crab-eating-fox over a boa under the daylight.

...

Laiba Shafique1*, Mahroze Fatima2, Syed Zakir Hussain Shah3, Muhammad Afzal4, Huma Naz5, Saif ur Rehman1 and Qingyou Liu1*

...stinal digestive enzymes activity and bone mineralization of Ctenopharyngodon idella. Four type food were prepared by using formic acid (%) and vitamin D3 (IU/Kg) in experiment viz, FD1, FD2, FD3 and FD4, respectively. Fish fed with formic acid showed considerable increase in calcium, magnesium potassium, however vitamin D3considerably increase iron and manganese contents (µg/g) in the bones of C. idella. Amylase and protease act...

Nabila Khan1, Imran Ahmad2 and Muhammad Bilal Sadiq1*

...DPPH) radical scavenging activity were used as response variables. Almond hull extract was chemically characterized by Fourier transform infrared spectrometer (FTIR) and gas chromatography mass spectrometer (GCMS). The extraction conditions were optimized by using independent extraction parameters; sample to solvent ratio (1:20-1:40 w/v), solvent concentrations (20-80%, v/v) and time (10-30 min), whereas, TPC and DPPH were used as response variables. At optimi...

Albina Gabdrakhimovna Darmenova1, Samat Ravkhatovich Yusupov2, Abzal Kenesovich Kereyev1*, Mirzabek Gashimovich Zukhrabov2, Yerbol Maratovich Sengaliyev1, Dosmukan Ermuhkanovich Gabdullin1, Berik Garipullievich Satybaev1 

...akhstan. The contraction activity of the uterine muscles after fetal excretion was studied by means of a device for determining uterine contractions, which consisted of a pressure rubber ball, discharge valve, manometer, handle, rubber tube, catheter, rubber camera, and rubber camera pin. Thirty minutes after fetal excretion, a 0.1 kPa decrease in uterine contraction strength and a 0.96 min reduction in the duration of the uterine contractions resulted in the ...

Mona M. Osman1, Kamelia M. Osman2, Manal Abu Elmakarem Mohamed1, Mahmoud E. Hashad2, Jeeser Alves Almeida3, Alaa Saad4, Octavio Luiz Franco5,6, Heba N. Deif 2* 

... production and catalase activity, for their possible roles in biofilm formation, antibiotic resistance and hemolytic activity of M. ovipneumoniae. The recovered sheep isolates of M. arginini and M. ovipneumoniae were examined bacteriologically and by PCR using Mycoplasma species-specific primers. MIC testing of the axenic isolates showed that 19 of them were 100% susceptible to tulathromycin, streptomycin, oxytetracycline a...

Rasha Ali Taha Hamza1, Atef Saad Osheba1, Hassan Mohamed Sobhy2, Sahar Hussein Abdalla Hekal2* 

... negative. Antibacterial activity of different galangal and sumac extracts against total bacterial count was more effective in burger prepared with Sudanese meat than burger prepared with Brazilian meat, where the highest synergistic antibacterial activity were recorded with the combination of Galangal and sumac extracts (250ppm Galangal +250ppm Sumac), which ranged from 1.75×104 and 5. 75×104 at zero time of sto...

Jiang Wu*

...nvestigate antibacterial activity of chemical constituents of Taraxacum officinale against foodborne pathogens. A total of 133 retail meat products were randomly purchased from different supermarkets. All samples were isolated and identified by conventional methods as Staphylococcus aureus, Salmonella, Escherichia coli and Listeria monocytogenes. Different bacteria were respectively inoculated into LB medium, the OD600 was adjusted to 0.5, and the initial bact...

Maria Qibtia1, Sehrish Faryal1, Muhammad Wasim1, Farzana Chowdhary1, Muhammad Tayyab1, Ahmed Mansovuri2, Zeeshan Ahmed2, Muhammad Hamid3 and Ali Raza Awan1,*

...hlorizin hydrolase (LPH) activity in enterocytes. The Single Nucleotide Polymorphism (SNPs) associated with occurrence of LP/LNP are different for European, Asian, African-American, Northern African and Arab populations. In this study, we studied, the association of these SNPs with LNP in Pakistani patients. Our analysis has evaluated the association between the development of LNP trait and two common variants in intron 13 and 9 (13910-C/T and 22018-G/A) along...
Mubasshir Sohail*, Qadeer Ahmed Soomro, Raza Muhammad, Muhammad Usman Asif and Imran Rauf
...to evaluate cellulolytic activity which was detected in the gut of mango mealybug, (Drosicha stebbingi). Initially, cellulolytic activity was detected from crude proteins using substrate-agar plate assay and laterally confirmed by endoglucanase assay. Enzyme activity measured using the glucose standard curve was 725 U/ml after acetone precipitation. Thermal stability and optimum temperatur...

Suhu Duan, Zaiqiang Li, Zhenzhen Fan, Mengran Qin, Xiaoxue Yu* and Liuan Li*

... were fed outdoors in an activity area of 63 m2 with free food and portable water. The CK was fed basic diet, and the experimental group added 1%, 3% and 5% linseed oil to the basic diet (TP1, TP2, TP3), respectively. On the 10th, 25th and 40th day of the formal trial, 36 eggs were randomly selected from each group, of which 12 were used to detect egg quality and 24 to detect monounsaturated fatty acids in eggs. The results showed that a certain proportion of ...

Serdar Bektas* and Ozer Ayik

...-phosphate dehydrogenase activity, blood samples were taken 1,3,7,14 and 21 days after the infection. Total red blood cell values, were significantly decreased in 7 and 21th day, a significant decrease in hemoglobin concentration noted only in the 21th day, significantly lower values in hematocrit, were observed at 7, 14 and 21th days, total leucocyte and thrombocyte counts, found significantly higher only in the 3th day, comparing with the control group. Whil...
Yuechen Li1, Yumo Li1, Xuefeng Zhuang1, Guangfu Lv2, Xiaowei Huang1, Zhe Lin1, Yuchen Wang1* and He Lin1*
...anced the SOD and GSH-Px activity in brain tissue, and increased the IgA, IgG, IL-1 and IL-2 level in serum. In addition, OR significantly improved the protein expressions of Nrf2, HO-1 and NOQ1 in the brain tissues of aging mice, which was detected by western blotting. In conclusion, OR treatment improved behavioral disorders and brain damage in the aging mice, suggesting that OR has the potential to be a new anti-aging drug candidate.

...

Momotaz Khanom*, Sheikh Mustafizur Rahman, Muhammad Yousuf Ali, Md. Shahin Parvez, Al-Hasan Antu, Md. Nazmul Ahsan 

...ificantly higher amylase activity in comparison to other feeds, while protease activity was comparable among the feeds except for DT. The results suggest that formulated feed can be used as a potential substitute for live Tubifex for the early stage of larvae of stinging catfish.

Keywords | Enzyme activity, Formulated feed, Growth performance, Stinging catfish, Tubifex 

...

Seun Eui Kim1,2*, Myoung-Hoon Lee1, Hye Myoung Jang2, Garam Park2, Wan-Taek Im3, Gwang Joo Jeon2,4* 

... Although the anticancer activity of a rare ginsenoside compound K (CK) against various cancers has been reported, there are few studies on neuroblastoma. In this study, cell viability and cell migration assay were tested and the expression of 17 genes in related signaling pathways was analyzed to determine the potential of CK as an anticancer agent for neuroblastoma. For the study of human neuroblastoma, SK-N-MC cells were studied. IC50 values were 33.06 μ...

Zhongqing Wang1, Qiuyue Wu1, Ruiling Ye1, Fazul Nabi1,4, Yangfei Shang1, Sarfaraz Ali4 and Juan Liu1,2,3*

...MP showed anti-diarrheal activity which maintained immune barrier in intestinal mucosa through regulating the quantity of iIELs and soothing the duodenal inflammatory injury might via NF-κB inflammatory pathway.

...

Feng Xu, Weijing Fan and Guobin Liu*

...ifferent doses. The cell activity and apoptosis rate of HUVECs were analyzed by CCK-8 method and flow cytometry, respectively. The levels of intracellular catalase (CAT), superoxide dismutase (SOD) and malondialdehyde (MDA) were measured using commercial kit, and expression levels ofNEXN-AS1 and miR-410-3p were detected using real-time quantitative PCR analysis. The dual luciferase experiment was applied to verify the targeted relationship betweenNEXN-AS1 and ...

Tao Ren1, Guiqiu Cao2, Xiao Han3, Feng Tan1, Qiaoli Chen4, Shicheng Yang5 and Haiyan Zhang6*

...o isolated for caspase-3 activity. Our result showed that naringenin pretreatment significantly increased cardiac dysfunction via scavenged free radicals and a reduction of inflammatory reaction. Dose-dependent treatment of naringenin significantly altered the CK-MB, HDL, LDL, creatinine, cholesterol, CRP, Ca2+, Na+ and K+, respectively. A significant alleviating change in these biochemical parameters along with caspase-3 activity

Amjed Ali1, Muhammad Tayyab1*, Abu Saeed Hashmi2, Asif Nadeem3, Shumaila Hanif4, Sehrish Firyal1, Shagufta Saeed1, Ali Raza Awan1 and Muhammad Wasim1

...rated the maximal enzyme activity at 37 °C in 50 mM sodium phosphate buffer pH 7. The presence of EDTA in the activity assay mixture reduced the β-lactamase activity to 91% while Zn2+, Co2+, Mn2+ enhanced the enzymatic activity to 144, 121 and 108% when used at a final concentration of 1 mM. The ionic and non-ionic detergents showed slight inhib...

Soliman Mohammed Soliman1*, Mohsen Mahmoud Shoukry2, Ahmed Mohammed El-Okazy1, Ahmed Mahmoud El-Morsy1, Mahmoud Mohammed Soliman1

...t on physiological rumen activity. Moreover, milk yield and milk composition were not affected. However, the concentration of milk urea nitrogen (MUN) was significantly decreased. Overall, these results indicate that treated SBM with levels of 200 or 250 PP reduced its degradability in the rumen more than untreated SBM. Also, recorded decreased gas and methane production had no effect on milk production.
 
Keywords | Soybean meal, ...
Chinar Mustafa Mohammed1*, Thamer M. Bashir1, Omar A.M. Al-Habib2, Farhad Ramadhan1, Mohammed Bassam1
...s, including antioxidant activity, modulation of calcium homeostasis, and antiapoptotic effects. There is mounting evidence supporting the utility of taurine as a pharmacological agent against heart disease, including chronic heart failure. This study investigated the potential protective effects of taurine, on behavior and cardiovascular function in the male rat following arrhythmia induced by the social stressor. Here, we studied levels of heart electrical <...

Tri Untari1*, Sitarina Widyarini2, Michael Haryadi Wibowo1, Marla Anggita1 

...as aimed to evaluate the activity of red ginger powder, ethanolic extract, and essential oil as immunostimulant agent during NDV challenge in vivo. Chickens were divided into seven groups of different treatment regimens. Group I - IV were vaccinated NDV while group V-VII were unvaccinated. Each group was treated with either red ginger powder (group I and V), ethanolic extract (group II and VI), essential oil (group III and VII). Group IV served as the untreate...
Gamalat Y. Osman1, Elham M. Hassan1*, Tarek A. Salem2, Azza H. Mohamed1
...justify;">Anti-parasitic activity of the fenugreek crude seeds water extract (FWE) on Schistosoma mansoni infected mice was studied in the present work and Praziquantel (PZQ) was applied as a standard drug. FWE was chemically analyzed by the high-performance liquid chromatography (HPLC) technique. The main recorded constituents were rutin, P-coumaric, hydroxyl-benzoic acid, ferulic acid, and sinapic acid. Results of the present study indicated that FWE (0.5 ml...

Ghulam Abbas1*, Muhammad Arshad1, Muhammad Saeed2*; Safdar Imran3, Ashgar Ali Kamboh4, Duraid KA Al-Taey5, Muhammad Asad Aslam1, Muhammad Saeed Imran6, Muhammad Ashraf3, Muhammad Asif7, Abdul Jabbar Tanveer8, Razia Abdul Majid Qureshi9, Maria Arshad1, Hussain Ahmed Khan Niazi1, Muhammad Tariq10, Sikandar Abbas1 

...sed mainly to combat the activity of Salmonella and Escherichia. They also enhance the uptake of digested proteins and important minerals. The advantages of using OA as feed additives greatly outweigh their disadvantages like decreased palatability. Organic acids can increase egg productivity and enhance the egg quality in layers. In broiler, use of OA is associated with improved weight of birds and feed conversion ratio. Dietary OA showed 1.85-8.48% increase ...

Iram Liaqat1*, Umaima Bibi2, Muhammad Arshad3 and Najma Arshad2*

...phus jujuba. Antioxidant activity was determined by total phenolic content determination, Pyrogallol method, 2,2-diphenyl-1-picrylhydrazyl (DPPH), hydroxyl radical scavenging assay, and free-radical-scavenging assay. Results revealed that O. vulgare and T. vulgaris possess high free radical scavenging capability and significant antioxidant activity. On the other hand, H. officinalis plant extracts exhibited low free radical ...

Marwa Ragab Saeed Abdallah, Hussein Mohamed Hussein Mohamed, Mohamed Mohamed Talaat Emara, Mai Atef Mohamed

...ontents, high scavenging activity) and the highest sensory quality among the different treatments. The composite treatments extended the wholesomeness of pastirma to 16 weeks at 5 °C in comparison with 12, 8, and 4 weeks for uncoated vacuum-packed, aerobically packed WPI/BW, and untreated control samples, respectively. Therefore, the application of WBI/BW edible coating before packaging of pastirma may be safely used at a commercial scale to extend the dur...

Iftikhar Alam1*, Muhammad Ali2 and Muhammad Farooq3*

...ata on food and physical activity were collected using a set of food and lifestyle photos, which were intended to describe various situations of on-campus food and active lifestyle environment. Students identified support and barriers for healthy eating. They also identified barriers and support for active lifestyle on campus. The support and barriers identified by students coded under themes of food and active lifestyle environment. Themes related to nutritio...

Juweria Abid1, Hooria Latif2, Amir Sohail2, Saroosh Fatima Tahir Syed2, Shakeel Ahmad3, Tooba Asif4 and Muhammad Farooq5*

...% with moderate physical activity. SCOFF questionnaire results showed 90% of positive results while the 10% of the population need further examination. The collected data results were mostly positive for example normal BMI ranges were found with a percentage of 57.3, the rate of binge eating in shorter periods was found to be rare and also no prominent binge eating was noticed during exam days which means no notable presence of any Eating Disorder was found bu...

Nawal Abd-elhafez Hassanain1, Raafat Mohamed Shaapan1*, Ahmed Maher1, Ahmed Badwi Yousif2, Gomaa Desoky Emam2 

...>

Keywords | Cross reactivity, Febrile, Malaria, Brucellosis, Typhoid fever  

...

Syeda Rubab Zaidi* and Safdar Ali Mirza

...oved production, laccase activity of crude extract i.e. 10.89U/ml increased to 15.07U/ml with purification of the enzyme, the purified samples of enzyme was significantly greater protein concentration than crude sample so, the optimum pH was 5.0 for laccase activity and the enzymatic extract was thermostable up to 60oC for 1 hour with guaiacol as substrate. The biological production of enzyme have an ecofriendly impact in cu...

Rawda S. Mohamed1,2, Mohammed Y. Matoock2*, Abeer H. Abdelrazek2 

...lus maze, and dark light activity box tests. Swiss Multiple Acute concurrent Stress (SMAS) showed more responsiveness to MAS than Balb/c Multiple Acute concurrent Stress (BMAS) in most biochemical and behavioral parameters, with an elevated level of corticosterone and MDA IL-6, and TNF-α and reduced levels of GSH. In conclusion, SMAS showed a more effective response to MAS than BMAS, making them a selection model in stress research.

Keywords | Mu...

Sri Melia1*, Indri Juliyarsi1, Yulianti Fitri Kurnia1, Evy Rossi2, Hurriya Alzahra3

...media, and antimicrobial activity against Escherichia coli: O157, Pseudomonas, Listeria inokua, and Klebsiella pneumonia; and (3) Molecular identification of LAB by analysis of the base sequence of the 16S RNA gene. The whey for this study was collected in Lasi Farm in Agam Regency, West Sumatra, Indonesia. The data was subsequently subJected to descriptive analysis. The bacteria obtained were rod-shaped that were catalase negative and homofermentative. Lactic...

Yasmin M. M. Mahmoud* 

... and globulin as well as activity of aspartate aminotransferase (AST) and alanine aminotransferase (ALT) were significantly (P<0.05) increased while, glucose, total cholesterol, uric acid and creatinine were significantly decreased (P<0.05) in G1 as compared to unsupplemented group. Kids in G1 group recorded the highest (P<0.05) concentrations of hemoglobin, mean corpuscular volume and mean corpuscular hemoglobin, while, G0 had the lowest value. Meanw...

Imtiaz Ahmed*, Imran Khan and Zia Ud Din

...contents and antioxidant activity. In this study, chamomile and wild thyme powders were first mixed at equal proportions and wheat flour was then replaced with the mixture at 1 , 2 and 3 % incorporation levels, to prepare composite test bread.Total polyphenols, total flavonoids content and antioxidant potential of the wheat flour, chamomile powder, wild thyme powder, mixture of chamomile and wild thyme at the ratio of 1:1, control bread and composite test brea...

Harpreet Kaur* and S.S. Hundal

...prid on the AChE and GST activity in earthworm Eudrilus eugeniae and Metaphire posthuma. E. eugeniae and M. posthuma were exposed to soil spiked with different concentrations (0.3, 0.6 and 1.0 mg/kg dry soil) of imidacloprid under laboratory conditions. The activity of AChE and GST have been reported as potential biomarkers to assess toxicity levels, hence the activity of these enzymes wer...

Muhammad Ajmal Khan1, Muhammad Yahya2*, Ali Hazrat2, Javed Khan3, Saeed Jan4, Tabinda Nowsheen2 and Inam Ullah5

...tents. The antibacterial activity of methanolic leaves extract of T. camphoratum was carried out against Gram-positive and Gram-negative bacterial strains through agar well diffusion assay (small wells were made with cork borer and 6μl of plant extract was added to the wells). The antioxidant activity of methanolic leaves extract was evaluated through a well established protocol 2,2-diphenyl-picrylhydrazyl hydrate (DPPH) ...

Xiaoguang Su1,*, Yanjun Gao2, Yanling Wang1 and Yaohui Ma2

...ulate its expression and activity. We concluded HAE may inhibit keloid fibroblast proliferation and promote apoptosis by regulating the miR-128-3p / EPHB2 molecular axis.

...

Liyun Chang1, Aiju Liu2, Jianshuang Zhang3, Yingbin Chen1 and Zhiyong Liu4*

...ing solution. No cross-reactivity was observed with the positive serum of Eperythrozoon, Trichinella spiralis (T. spiralis) and Hydatid cysts. The coefficients of the inter- and intraassay variations in the repeatability tests were lower than 10%. The established method and the indirect hemagglutination (IHA) test were used to detect 50 clinical samples at the same time. The positive coincidence rate of the two was 94.11%. Therefore, the newly established indi...

Eman A. Al-Shahari1,2, Eman R. ElBealy3, Abdelhalim A. Alkhazendar4 and Abeer A. Alm-Eldeen4*

... through its antioxidant activity. Therefore, the present study was designed to investigate the possible role of quercetin in modulating liver’s function and structure in aged male rats. Forty eight male albino rats (3 and 30 months old) were used. Half of the rats at each age received 200 mg quercetin/Kg every other day for 2 weeks. Thirty months old rats showed a decrease in the liver AST, albumin, SOD, CAT and GPx while showed an increase in the liver...

Mehroze Amin1, Afifa Yaqub1, Qindeel Fatima1, Rabail Hassan Toor1,3 and Abdul Rauf Shakoori1,2*

...to favor p53 anti-cancer activity and promote apoptosis and cell senescence in cancer cells. It is also known to decrease the incidence of several cancers though it is not entirely true for breast cancer. In the present study, the effect of metformin has been studied on the expression of p53 and its interacting partners MDM-2, PIRH2 and ΔNp73 in breast cancer cell line MCF-7 and non-cancerous kidney cell line HEK2093. Analysis of the cytotoxicity and pro...
Afifa Yaqub1, Mehroze Amin1, Qindeel Fatima1, Rabail Hassan Toor1,3, Saira Aftab1 and Abdul Rauf Shakoori1,2*
...explores the anti-cancer activity of UNC0642, a novel potent inhibitor of G9a in MCF-7 breast cancer cell line. Analysis of growth and proliferation parameters by various cell-based assays such as neutral red assay and BrdU cell proliferation assay showed that higher concentrations were lethal for the cancerous cells. IC50 was found to be 12.6 µM. Further contextualization of the therapeutic potential of G9a inhibition was provided by expression analysis...

Muhammad Rizwan, Abu Bakar Muhammad Raza*, Muhammad Zeeshan Majeed and Muhammad Arshad

...acts having insecticidal activity. The main objective of this study was to find out the toxic effect of various plant extracts against D. mangiferae. Three concentrations (i.e. 6.25, 12.5 and 25.0%) of leaf extracts of neem, Azadirachta indica A. Juss (Meliaceae), eucalyptus Eucalyptus camaldulensis Dehnh. (Myrtaceae), datura Datura stramonium L. (Solanaceae), batho Chenopodium album L. (Amaranthaceae) and Indian lemongrass Cymbopogon citratus (DC.) Stapf (Poa...
Ejaz Ur Rehman1, Shakeel Ahmad2, Fathul Bari3*, Tanveer Khan2, Naveed Ullah Khan2, Abdullah Khan4 and Romaan Hayat Khattak2
... ecology and time budget activity was investigated in 16 active nests at 6 different sites during the current study. Nest construction was primarily initiated by the male while female joined later on. Mean size of circumference of the nest was 3.27 inch, mean length of tunnel 2.82 feet. Clutch size varied between 1 and 5 with an average of 3.25 per nest. Both parents incubated the eggs which hatched after a duration of 15-18 days. Hatching success was 94% whil...
Faiza Ghazanfar1, Masood Rabbani1*, Aamir Ghafoor2 and Muhammad Hassan Mushtaq3

Malik Fiaz Hussain1, Atif Akbar2, Muhammad Asif1, Laraib Nisar3, Muhammad Naeem Ashiq3 and Furhan Iqbal1*

... can affect the muscular activity, object recognition capacity and exploratory behaviour of albino mice. The effects were more pronounced at higher dose and in female mice.

...

Heba S.S. Salem1, Hend M. Megahed2, Marwa M. Sarhan2, Maha M. El Alem3, Gehan N. Alagmy3* 

Ezz Ibrahim Khalifa, Ahmed Loly Ibrahim Desoky, Adel AbdElaziz Elbadawy, Gamal Ibrahim El-Emam, Tarek Messlam Mahmoud Mahdy* 

...eristics and biochemical activity of extender as compared to E0 extender through semen extender preservation. The best level of BBE is marked when added up to 1.5% in the E3 extender which improves all characteristics compared to E0 and other BBE extenders. Also, E3 indicated post-thawing sperm parameters as motility, live, normal, and integrity acrosome up to 47.50, 65.10, 65.66, and 69.67%, but it was 37.22, 49.78, 55.89, and 59.22% relative to E0 extender, ...
Allah Bakhsh1, Attiq Akhtar2, Fiaz Hussain3, Hafiz Wasif Javaad4, Inam ul Haq5* and Humara Umar
...rs (10.85%), antioxidant activity (75.75%) and minimum value of titratable acidity (0.15%). The results suggested that among studied fig cultivars, Black Ball is a premium fig cultivar having superior physical and chemical features which can be used in future breeding programs and establishment of commercial orchards in Soan Valley area of Punjab, Pakistan.

...

Shailendra Sharma, Smriti Shrestha, Naresh Pandey and Laxman Khanal*

...itors. Out of the entire activity budget, resting (49.27%) constituted the highest proportion, followed by feeding (22.93%) and grooming (12.59%). There was a negative association between the grooming behavior and the number of visitors; however, no significant difference was observed in grooming proportion before and after visits. Higher levels of disturbance had a significant negative effect on the grooming frequency and time investment. The non-lactating ad...

Hassan Raza1, Muhammad Zeeshan Majeed1*, Muhammad Irfan Majeed2, Mujeeb-Ur-Rehman1 and Muhammad Asam Riaz1

...re inspected for termite activity at 15 and 30 days post-treatment. Results of initial in-vitro trials indicated that formulated beads remained intact and did not disintegrate by consecutive episodes of wetting and drying and were able to attract more than 50% termite individuals exposed. This formulation suppressed the termites in field as no termite foraging was recorded inside the bait-treated monitoring stations for about a month post-treatment, while the ...

Entesar Z. Eliraqy1*, Basant M. Shafik2, Yasser S. Hussein1, Abdelwahab A. Alsenosy3, Emad A. Abd allah1, Mohamed F. Saad1 

...eserving, also enhancing activity of sperm during different period storage. Current paper gives an apprise on the usage of garlic (Allium sativum) extract as an alternative additive for sperm preservation in buffalo bulls at animal production research institute, Sakha, Kafr El-Sheikh Governorate, Egypt. The experimental protocol was designed as four groups (Control, G1, G2 and G3). Buffalo-bulls’ semen were exposed to different concentrations of garlic e...

Muhammad Waseem Akhtar1*, Khalid Mahmood Khawar2, Muhammad Naeem Akhtar3, Muhammad Rafique1, Khalid Hussain4, Sharmin Ashraf1 and Muhammad Fida Hassan1

...on, the current research activity is planned to screen out available germplasm of chickpea against dhora beetle (Callosobruchuschinisensis). For this purpose, 8 genotypes of chickpea genotypes were taken from Ayub Agricultural Research Institute, Faisalabad. 1 kg of each genotype was taken in plastic jars. There were three replications of each genotype for each insect. Twenty adults of dhora beetle were discharged in each container which were enclosed with mus...

Reem M. Ramadan1, Fady Sayed Youssef2, Gehad Genidy Mohamed3, Sameh Hamed Ismail4, M.M. El-Bahy1, Shimaa Abdel-Radi1* 

...composite, anticoccidial activity, Comet assay, Poultry, coccidiosis. 

...

Hurriya Alzahra1, Susmiati Susmiati2*, Sri Melia3 

...etermine the antioxidant activity, total phenol, and organoleptic characteristics including the taste, aroma, and texture of fermented milk with orange juice added (Citrus nobilis L.). The study was based on a Factorial Completely Randomized Design (CRD), with starter concentrations of 4 (A1), 5 (A2), and 6% (A3), as well as orange juice concentrations of 10 (B1), 15 (B2), and 20% (B3). The results showed that fermented milk with orange juice revealed antioxid...

Aulia Nurul Saputri, I Komang Gede Wiryawan, Dilla Mareistia Fassah*, Dewi Apri Astuti 

...ates showed no hemolysis activity. Three isolates (A3, A4, and B1) are molecularly identified as Enterococcus faecalis which showed a potency as probiotic candidate. We conclude that Enterococcus faecalis is a potential probiotic that can be isolated from BSF larvae.

Keywords | 16S rRNA Gene; BSF Larvae; Chicken Manure; Lactic Acid Bacteria; Palm Kernel Meal 

...

Juweria Abid1, Shakeel Ahmad2, Humaira Wasila3, Tooba Asif4, Muhammad Farooq5* and Attaullah Jan6

...ompounds and antioxidant activity of fresh (cow, buffalo, goat, sheep and camel) and processed milk types (S1, S2, S3, S4 and S5) commonly consumed in Khyber Pakhtunkhwa (KP), Pakistan. Samples were collected from three different districts of KP and after composite sampling dried in oven and stored at room temperature for further biochemical analysis. Samples were then analyzed for minerals content, total phenolic compounds, total flavonoids and antioxidant

Shakeel Ahmad1*, Humaira Wasila2, Juweria Abid3, Nazir Muhammad4 and Hazrat Usman5 

...ompounds and antioxidant activity of milk products commonly consumed in Khyber Pakhtunkhwa, Pakistan. Fifteen different milk product samples were collected from 3 different markets in the study area to get a composite sample. AOAC 15th edition methods were used to analyze moisture, ash, carbohydrates, fats and protein contents of milk products. Atomic absorption spectroscopy and flame photometry were used for mineral analysis. Total phenolic compounds were eva...

Abhishek Pandit1, Suman Poudel2, Manish Gautam3* and Shambhu Shah4

...Progestin suppresses the activity of the ovary and inhibits the dominant follicle maturation due to the suppression of both FSH and LH. Gonadotropin-releasing hormone or an analog is administered with PGF2α to estrous- cyclic and noncyclic cattle disrupts the patterns of follicular growth, inducing ovulation on a large follicle. To select and successfully implement the estrus synchronization regime in animals’ proper knowledge of the hormonal profi...

Maham Tariq, Aqsa Akhtar and Nauman Khalid*

... the highest antioxidant activity was observed in candies containing 30% (w/w) carrot juice and 10% (w/w) fennel extract. The formulated candies showed a good sensory profile and can be utilized as a potential source of functional candies for improving the nutritional profile of children.

...

Fawziah M. Albarakaty* 

...ology: The antibacterial activity of plum (Prunus domestica L.) peel extracts in hоt and cold aqueous and ethanol extracts against specific medically significant pathogens isolated from cows and poultry farms were assessed. Additionally, the phytochemical composition of the aqueous and ethanol peel extracts was examined. Results and conclusion: According to the findings, the plum (Prunus domestica L.) peel extracts have аlkaloids, flavonoids, tаnnins, and s...

Xiajun Zhang1, Jie Yang2, Wenjun Zhou1, Zhenshi Chen2, Weidong Wu3, Shaoru Zhang2 and Lihui Wang2*

...SMAD3 and SMAD4. Pathway activity shows ASPN and TGF-β1 and TGF-β3 activate EMT. Finally, we speculate that lncRNA CASC7 inhibited miR-26, inhibited ASPN, inhibited TGF-β, and promoted XIAP, to activate SMAD/XIAP pathway, improving the survival rate and invasiveness of endometrial cancer cells. Collectively, this is the first time to describe the mechanism of lncRNA CASC7/miR-26/ASPN/TGF-β/Smad axis in the proliferation and invasion of endo...

Ahmad Nadeem1,2 and Rubina Arshad1,2,*

...ree possessed antifungal activity. One promising wild type isolate (LPA6) was subjected to gamma irradiation for mutation induction. Seeds of two chickpea varieties were inoculated with LAB isolates in four treatments comprising of T1 (wild type LPA6), T2 (mutant MLPA6), T3 (wild type LPA6 + mutant MLPA6 consortium) and T4 (un-inoculated control). Inoculated and uninoculated seeds were sown in net house in three replicates. In kabuli variety, maximum increase ...

Sehrish Akram1, Abida Butt1* and Shakil Ahmad Khan2

...ntagonism and antagonism activity in silkworm larvae in silkworm larvae. The results of our study provide useful data for the assessment of ecological risk of the tested compounds (single or mixture) against different silkworm instars.

...
Farzana Bashir2, Aysha Saleem1, Khalid Iqbal Khichi2, Rubina Nelofer3* and Rauf Ahmad Khan2
...iques. The antibacterial activity was determined by column studies using response surface methodology (RSM) based on three levels, three factorial Box Behnken Design (BBD). The significance of independent variables (flow rate, bacterial count and column height) and their interactions were tested by means the analysis of variance (ANOVA) with 95% confidence limits. The antibacterial susceptibility was optimized for flow rate, bacterial count and column height. ...

Sahar M. Saber1*, Ahmed M. A. Albehwar2, Amani M. Abas3, Omaima A.A. Alshamandy2, Noha A. El said4 and Marwa Y. Hamad4

...erferon has an antiviral activity against RVFV and further studies are needed to provide more understanding of the virus-host interaction and cellular antiviral response and to evaluate the probable side effects of interferon on treated animals.

...

Aslı Çilingir Yeltekin

...dants (SOD, CAT, GSH-Px) activity in Van fish kidney and muscle tissue after 24., 48., 72., and 96. h of tebuconazole exposure at a concentration of 2.5 mg/L. The obtained results indicated that caspase-3, 8-OHdG, and MDA levels significantly increased compared to the control (p < 0.05). The kidney and muscle tissues indicated a significant decrease in antioxidant enzyme activities (superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH...

Anum Syyam1,2, Nazish Saqlain1, Sidra Hareem1, Naghmana Mazhar1, Liaqat Ali3 and Samia Afzal2*

...nd anti-B with hemolytic activity were present in 10.8% and 5.1% donor samples, respectively. IgG type anti-A and anti-B alone were observed in 9.1% and 3.4% donor samples, respectively while both IgG type anti-A and anti-B were observed in 1.7% donor samples. Gender, age and Rh blood group did not have any significant impact on anti-A and anti-B titer frequencies. To conclude IgM and IgG anti-A and anti-B antibodies exist in significant frequencies and titers...

Fahrauk Faramayuda*, Soraya Riyanti and Sitty Mahanadhiandinie

...hown to have antioxidant activity. This study aimed to determine the antioxidant activity of white tea leaves grown in Indonesia using extraction methods other than brewing, i.e., maceration. Study of free radical scavenging activity of 1,1- Diphenyl-2- Picrylhydrazyl (DPPH) and the determination of the total polyphenol content of white tea leaves have been conducted using UV-Visible spect...

Emtiaz Ibrahim Ghoniem, Gaber Mamdouh Abdelgalil, Amira Farouk Gad* and El-Sayed Hassan Eshra

 
... study suggests that the activity of these enzymes modulation may be one of the biochemical mechanisms of CuSO4 toxicity. 
 
Novelty Statement | This is the first study to investigate the sub-lethal effects of CuSO4 on biochemical interactions of land snail, Theba pisana. Our findings will contribute to understand the biochemical defects of CuSO4.
...

Hafiz Husnain Nawaz1*, Ayesha Ahsan2, Amir Afzal1, Muhammad Ashraf Sumrah1, Muhammad Jan1, Kashif Ali1, Muhammad Arsalan1 and Rizwan Latif3

Shahrokh Mojarradgandoukmolla* and Hasan Akan
... such as hepatic enzymes activity, glucose, lipid profile, ESR, CRP, renal function tests, and oxidative biomarkers were measured. Histological evaluation was also performed. Among the hematological parameters in the treated groups, only lymphocytes showed a significant change in the treated group with T. uncinata. The levels of liver enzymes, lipid profile and glucose in the ethanol group increased significantly compared to the control, while these par...

Uzma Hameed1*, Aneela Liaqat1, Muhammad Asjad Khan2, Ikram-Ul-Haq1 and Maham Aslam1

...rable increase in enzyme activity (4.5±0.031 U/ml) was observed when diluent with initial pH of 7 was used. Among different carbon sources (maltose, glucose, starch, galactose, arabinose and sucrose) best results were obtained with soluble starch. Alpha-amylase production is sensitive to the supply of nitrogen sources. In this context, both inorganic and organic nitrogen sources, were evaluated. Optimal enzyme production was obtained with diluent supple...

M. Mansoor Javed*, M. Aslam Mirza, M. Aziz ur Rehman and M. Saif ur Rahman

...OH solubility and urease activity prior to inclusion in the experimental diets. A day old Cobb-500 broiler birds (n=432) were purchased commercially. Nine iso-caloric as well as iso-nitrogenous experimental formulations as starter diets (CP 22 %, ME 3000 Kcal/kg), grower diets (CP 20.5 %, ME 3075 Kcal/kg) and finisher diets (CP 19 %, ME 3150 Kcal/kg) were formed as per nutritional recommendations for Cobb-500 and assigned to 36 replicates (four replicates/trea...

Jinzhao He1, Pengfei Feng2, Junqi Qin2, Yun Teng1, Xu Luo2*, Zigui Chen1*, Huawei Ma2* and Dayan Zhou1

...m the change of tyrosine activity in the body. The in-depth study of its regulatory mechanism contributes to understanding the genetic mechanism of red tilapia and improving the body shape.

...

Sayed H. Al Habty1, Dina N.Ali2* 

...tisfactory antibacterial activity Minimum Inhibitory Concentration (MIC) at 10mg/ml and Minimum Lethal Concentration (MLC) at 40mg/ml. The results revealed that 40mg/ml LF in yogurt could inhibit MDR S. aureus at 2nd day while, 20mg/ml at the 4th day. The study concluded that LF can be used as a bio preservative in yogurt due to its highest antimicrobial activity and acceptable sensorial properties.

Keywords | MDR, A...

Maha Mostafa1, Sohail Soliman1, Reham I. Mohamed2 and Wael M. El-Sayed1*

... in the acid phosphatase activity. It also directly reduced the concentration of free testosterone and estradiol in both sexes without any apparent effect on LH or FSH hormones. It increased the total cholesterol in males only and elevated the triacylglycerols and glucose levels in both sexes. The administration of testosterone to males, females, or both reduced the fertility index to zero. The mating success was also reduced from 80 to zero when both the male...
Farah Abid1,2, Mohammad Saleem1,3*, Tahir Maqbool4, Tania Ahmed Shakoori5, Faheem Hadi4, Tahir Muhammad4, Saira Aftab4, Yasir Hassan7 and Shabana Akhtar4,6*
...atory and anti-arthritic activity which could have beneficial impact for the patients associated with arthritis.

...

Shaolin Zeng, Shuai Yuan* and Kai Liu

...sevoflurane promoted the activity of SOD, CAT as well as GSH-Px, and inhibited MDA and ROS levels, while miR-26a-5p inhibition expression content inhibited the increase in activity of SOD. To conclude, the post-ischemic treatment with sevoflurane is able to inhibit PTEN expression to promote the activation of PI3K/Akt signaling pathway by increase in miR-26a-5p expression level, thereby playing a role in resisting myocardial...
Alia Tajdar1,3, Shaghef Ejaz2, Muhammad Shah Zaib1, Anum Ishfaq1, Syed Muhammad Zaka1*, Hafiz Muhammad Safeer1 and Khalid Abbas1
...d the highest repellence activity against B. zonata. Moreover, no side effects were observed on the post-harvest quality of banana treated to different methanolic extracts as compared to control. This shows that botanical extracts could be used for the control of B. zonata and for the better post-harvest management of fruits.

...

Ghulam Akbar1*, Muhammad Anjum Zia1, Amer Jamil1 and Faiz Ahmad Joyia2

...wn the highest enzymatic activity with UV-Et mutant 680.0 UmL-1 and with CaCO3 UV-Et mutant has been found to give the relatively lowest enzyme activity 652.01UmL-1. While UV-mutant has shown maximum enzyme activity 275 UmL-1 with the addition of K2HPO4 and this mutant shown minimum 57 UmL-1 with the addition of FeSO4. 7H2O. he parental strain expressed maximum enzyme

Nazish Manzoor1*, Alim Khan1, Muhammad Yaseen1, Abid Ullah1, Zulqarnain2 and Iftikhar Jan2

...terial strain N1 and its activity was checked at distinct pH and temperature. The optimum pH was from 6-8 whereas the temperature was 40 °C. Saccharomyces cerevisiea was added for enhanced fermentation and ethanol production. The acid pretreated sample produced the highest ethanol (15.2%) than the alkaline. The percent production of ethanol and the amount of sugar in pretreated samples was confirmed using High-Performance Liquid Chromatography (HPLC) and s...

Amir Abdullah Khan and Muhammad Irfan*

...nd tested for antifungal activity using the streak plate method. Among them, one bacterium was found to be antagonist against the pathogen. This was identified as Bacillus subtilis 2i through 16SrRNA. The disease causing fungus was also isolated and identified as Schizophyllum sp. B2A through 18SrRNA.The strain Bacillus subtilis 2i was cultivated in sub-merged fermentation for the production of bioactive compounds. Various parameters were optimized to obtain m...

Müge Aliye Hekimoglu and Sırma Sönmez

...as used to determine the activity of enzymes. The results showed that supplementation of 2000 mg/kg of dietary significantly increased weight, length and specific growth rate (P < 0.05). While no change in colour was observed in the control group at the end of the experiment, it was determined that carnitine could have a 27% effect on the colour change of fish in the other groups. Better results were obtained between the L-carnitine groups compared to the c...

Quang Minh Dinh1*, Tran Thi Huyen Lam2,3, Y Thi Nha Nguyen4, Thanh Minh Nguyen1 and Tien Thi Kieu Nguyen5

...compositions and feeding activity of Butis koilomatodon collected in six estuarine areas of Mekong delta from April 2019 to March 2020. A total number of 1,227 specimens of Butis koilomatodon (891 males and 336 females) were analyzed diet composition and feeding strategy based on the kinds of food they consumed. The results show that four main food categories were shrimps, small fish, Polychaeta, and detritus, of which the highest frequency of prey is shrimp w...

I Wayan Lanus Sumadiasa*, Enny Yuliani, Lukman Lukman 

...f Brangus bull after sex activity break for a long time. Moreover, the best quality of spermatozoa is found in supplementing 10% GF to Citrate with 10% egg yolk extender.

Keywords | Brangus bull, Chilled storage, Extender, Guava, Semen 

...

Wafaa M.A. El-Nagdi1, Ahmed E.A. Mahgoob2, Mahmoud M.A. Youssef1*, Entesar H. Taha2, Mona M.S. Zayed3 and Nora R.A. Saleh1

...before Ne. As for enzyme activity, peroxidase and polyphenol oxidase activities increased at the different degrees as influenced by the different treatments. When comparing on the basis of average percentages potential of peroxidase activity, the highest potential (2.446%) was recorded, when P. fluorescens was added, 3 days after nematode inoculation than the other treatments. Bacterium and nematode applied at the same time ...

S. Ahmed†, Q. Liu and H. Jian

...nd chitinase
activity was used as seed bacterization in green house experiments. In green house significant reduction in white
female development was observed for avermectin (84.53%) followed by B. cereus strain B48 (78.10%) as compared
to results of the untreated control treatment (P≤0.05).
...

A.H. Choshali1, S. Rezaee2, S. Jamali3, H. Reza3, Zamanizadeh4 and F. Rejali5

...g soil. The quantitative activity of chitinase and ß 1, 3 glucanase enzymes was assessed on 2, 4, 6 and 8th days after M. incognita inoculation based on split- plot in time design. Also the results showed that AMF pre-inoculation caused a significant decrease in RKN pathogenicity factors (number of galls, eggs, egg sacs and J2) in both tolerant and susceptible cultivars. Inoculation of susceptible roots with AMF significantly reduced the nematode pathoge...

Muhammad Shahid Nadeem*, Jalaluddin Azam Khan and Firoz Anwar

...on and 139 U/mg specific activity. Maximum enzyme activity was found at pH 8 and above 90C, its KM and Vmax values were found 25µM L-alanine and 149 U/min/mg respectively. In silico studies have shown that the enzyme was found in a monomer structure. Molecular docking studies with potential molecules involved in the reaction catalysed have been conducted and binding energy values were calculated for each molecule inclu...

Aqsa Javaid, Masoom Yasinzai* and Khunsa Saeed Kiyani

...CD). The optimal phytase activity obtained after CCD design was 132.32 U/mL at 35 °C, pH 6.5, inoculum density of 2.5mL after incubating for 24h at 75 rpm. Extracellular enzymes were then partially purified in 2 steps (ammonium sulfate precipitation and gel filtration chromatography using Sephadex G-50). The molecular weight of extracellular phytase from B. subtilis KT004404 estimated by SDS-PAGE was 30 kDa. The Km and Vmax of B. subtilis KT004404 phytas...
A.M. El-Baha1, A. A. El-Sherbiny2†, M. Z. M. Salem1, N. Shaarawy3 and N. H. Mohamed3
...iv>for their nematicidal activity at four different concentrations viz., 125, 250, 500 and 1000 mg/l against root-knot
nematode, Meloidogyne incognita under laboratory conditions. All concentrations significantly inhibited egg
hatching (31.24–66.35%) and mortality of second stage juvenile. Inhibition of egg hatching (%) and mortality (%) of
J2 were increased linearly with increasing concentration of EOs. Corymbia citri...
A. M. Khan1,†, S. Naz1 and M. Abid2
...div>javanica anti fungal activity against Fusarium moniliforme and Rhizoctonia solani and fertilizing potential on okra
Abelmoschus esculentus. It was observed that the soil sample which was mixed with algal powder supported the
growth of the okra plant and proved that the alga under investigation possessing some level of fertilizing potential.
...

A. S. A. Saad1, M. B. Al-Kadi1, A. A. A. Deeabes2 and A. M. El-Kholy2

...evaluate the nematicidal activity of some organic and inorganic compounds, as well as fosthiazate as a standard nematicide for their hatching inhibitory and juvenile mortality potential and to ascertain their role as organic amendments for the management of root-knot nematode (Meloidogyne incognita) affecting okra plants in vitro as well as in vivo conditions. Five concentrations of all chemicals were prepared. Data of in vitro studies showed a marked nematici...

A.A. Tanimola† and B. Fawole1

... that showed nematicidal activity in in vitro on
Meloidogyne incognita. The phytochemical analyses revealed that the Aloe species had similar phytochemicals:
tannins, saponins, flavonoids, cardenolides, phenols, alkaloids and anthraquinones. However, total phenol (14.3
mg/g), tannins (14.5 mg/g) and saponins (59.8 mg/g) were highest in AKY than in other aloes. Flavonoid content
(3.7 mg/g) was highest in AAR while...

S.A. Khan†, M. Abid and F. Hussain1

...to determine nematicidal activity against Meloidogyne javanica (egg
hatching and larval mortality tests) in vitro. Results revealed that seaweed biochemical potential in two different
solvents viz., water and methanol @ ratios 2.5, 5 and 10%. It is observed that Sargasssum tenerrimum, Padina
tetrastromatica and Melanothamnus afaqhusainii showed maximum egg hatching (96%) and larval mortality (99%)
and (100%), res...

O. A. Fabiyi

... column. The nematicidal activity of the fractions were
evaluated in the laboratory using a 4x4x3 factorial experiment, while the crude extracts were tested on
Meloidogyne incognita infecting Abelmoschus esculentus in the field. Three hundred juveniles were used for the
assessment. Acetone extract coded DNLO/Me2CO caused a significant increase in plant height, number of leaves,
number of fruits per plant and frui...

A.A. Anter, A.W. Amin†, A.H. Ashoub* and A.S. El-Nuby*

...tion.
Enzyme activity of both peroxidase and polyphenol oxidase were elevated in infected tomato roots than
healthy ones. Chemical activators showed enhancing in these antioxidant activities, indicating the SAR four
chemicals was occurred. In conclusion, CSA, NSA, BABA and SA have
...

A.W. Amin†, A.A. Anter, A.H. Ashoub* and A.S. El-Nuby*

...dant
enzymes activity for both peroxidase and polyphenol oxidase were elevated in bacteriazied plants as compared
nematode infected plant as well as total phenol content. Results revealed that crude culture suspension of bacteria
was more effective for reducing nematode population followed by cell-free culture filtrates, bacterial live cells and
bacterial dead cells, sequentially. It was concluded that bacteria h...

W.M.A. El-Nagdi†, M.M.A. Youssef and M.G. Dawood*

...tode-hatching inhibitory activity reduced nematode criteria including
number of galls, egg-masses and hatched juveniles on roots of eggplant and number of juveniles in soil at harvest
stage compared to untreated plants significantly (p ≤ 0.05). Lower concentration of the tested materials caused
higher percentages reduction the mentioned nematode criteria. Vice versa, increase in length of shoots, dry and fresh

Jax Vincent Gamulo, Maye Pearl Bolina, Jessica Serena Brion, Via Crishiela Nicole Dela Rosa, Roxanne Francesca Maglaya, Carl Lexter Tan, Aimee Caye Chang* 

...iffered in fasciolocidal activity (P < 0.05). Albendazole (62.5%) was the most used reference drug, along with Piperazine Citrate, and Triclabendazole, wherein ANOVA showed no significant difference in mortality time among them (P > 0.05). Notably, plant parts and extraction techniques used affected the resulting fasciolocidal activity of the plant extracts. Linear regression revealed a low inverse relationship between...

Rukhsana Anwar1*, Ammara Abd-Us-Sattar1, Afifa Noor2, Kanwal Ashiq1,3 and Shah Jahan4 

...ng enzymes; GST-specific activity, total glutathione, superoxide dismutase, catalase, and malondialdehyde were determined in liver homogenates. The phytochemical analysis of extracts revealed the presence of many important bioactive compounds. Real-time PCR results showed that aqueous extract decreased the mRNA expression of CYP1A2, CYP3A4. The methanolic extract decreased mRNA expression of CYP2C9 and CYP3A4. Both extracts enhanced GST-specific

Nuzhat Munawar1, Abrar Hussain1, Imran Sajid2, Zahra Noreen1, Muhammad Aslam3*, Zeeshan Rehman1 and Aamir Ali3,4

... not show any pronounced activity as compared to the negative control against E. coli and K. pneumoniae while it was inactive against other tested bacteria. Cytotoxic effect of all the extracts was also evaluated using micro well cytotoxicity assay against brine shrimp larvae where chloroform extract showed minimal cytotoxic level (23.37%) while acetone extract showed maximum cytotoxicity (65%).

...

Yanjie Liu

...natural killer (NK) cell activity, C3, C4, CH50 and body weight. We found that the levels of IgA, IgG, and IgM in the three groups decreased; while IL-2 levels increased, and the order can be ranked as control group>hypoxic group>high altitude group (P<0.05). Moreover, WBC, C3, C4, CH50, and NK cell activity of three groups decreased, and the comparison result was control group>hypoxia group>high altitude grou...

Dina N. Ali1*, Sayed H. Elhabtey2*, Manal M. Amin1  

...py (FTIR). Antibacterial activity of MO and Nano-MO was assessed against reference bacterial strains by using agar well diffusion method. The minimum inhibitory concentration (MIC) of MO and Nano-MO was 3% and 2%, on Listerea monocytogenes, Staphylococcus aureus, Salmonella typhi and E. coli bacteria, respectively. While, in inoculation of MO and Nano-MO in cheese complete reduction of examined bacteria was recorded at 3rd week of storage except for L. monocyt...

Owolabi Olutunmise Victoria1*, Saka Olusola Stephen2, Olashinde Oluwaseun Ruth1, Alli Smith Yemisi Rufina3

...educed glutathione (GSH) activity, Superoxide dismutase (SOD) activity and Malondialdehyde (MDA) activity. When compared control and glibenclamide-treated rats, the antioxidant activity of the extract increases with advancing the dose of treatment. According to the findings, Cola acuminata young leaves have comparable anti-diabetic efficacy to that of a ...
Safika1*, Ni Luh Putu Ika Mayasari1, Juliadi Ramadhan2
...h group. Resistance gene activity against each antibiotic can measure both the phenotype and genotype of Klebsiella pneumoniae resistance development.
 
Keywords | Antibiotic resistance, Cats, Feline respiratory, Klebsiella pneumoniae, Multi drug resistant
...

B. Archana and R. Saxena

...ed for their nematicidal activity against second stage juvenile of Meloidogyne incognita by in vitro technique. Aqueous extract of all plant roots exhibited nematicidal activity. LC50 values calculated as 1024 ppm for C. roseus, 1867 ppm for S. nigrum, 1968 ppm for A. spinosus, 3428 ppm for C. album and 962 ppm for O. sanctum. LC50 values showed that out of these extracts O. sanctum found to be the most effective. In vivo ex...

Tae-Kyung Eom1, Jae-Kang Lee1, Dong-Ho Lee1, Ho-Kyoung Bae1, Hyeongyu Ko1, Kyu-Jung Kim1, Sung-Cheol Jung2, Jong-Hwan Lim2 and Shin-Jae Rhim1*

...y;">Studies on the daily activity patterns of species can contribute to gaining an understanding of community ecology. During the warm seasons of the years 2019 to 2021, we used camera traps to monitor the activity patterns of water deer Hydropotes inermis, roe deer Capreolus pygargus, and Amur goral Naemorhedus caudatus in the Seoraksan and Jirisan National Parks, South Korea. We compared activity

Esam A Razin1, Hassan Sobhy2, Tarek R. AboElnaga1, Asmaa A. Darwish1*, Rasha S. Mohammed1

...ed its anti-trypanosomal activity in vitro before. This research aimed to study its effect against T. evansi in vivo. For this purpose, 28 parasite-free female rats were used, seven non-infected (control group (CG)), while the others were intraperitoneally injected with T. evansi and then equally divided into Trypanosoma Group (TG): which remained without treatment. Diminazene aceturate group (DAG): injected with Diminazene aceturate (3.5mg/kg) at 0, 14th, and...

Hesham A. Mahran1,2*, Shawky M Aboelhadid3, Saad S. Alqahtani4,5, Mohamed Z. Sayed Ahmed4,5

...was potent antibacterial activity even at the lowest concentrations. Moreover, CNE showed better pupicidal activity than the other forms with LC50 at 322 ug/mL lower than pure cinnamon oil, 465 ug/mL against pupae. Additionally, the CNE achieved the lowest concentration after 90 min (15.80ug/mL). The high concentration of 69.60ug/mL (LC50) and 135.00ug/mL (LC99) caused toxicity to adult C. pipiens in a short time (15 min). M...

Asmaa A. Darwish*, Mona A. Mahmoud, Adel M. El-Kattan 

...atrix metalloproteinases activity, T/HDL/LDL-hypocholesterolemia, and decreased minerals, electrolytes, and trace elements concentrations and these changes were more prominent in goat than in sheep. While, the diseased ewes suffered from higher degrees of leukocytosis, total hyperproteinemia, hypoglycemia, increased kidney function tests, and oxidative stress than the diseased does. Total antioxidant capacity (TAC) and Zn had the highest likelihood ratios amon...
Hafiz Abdullah Shakir1*, Iqra Javed1, Muhammad Irfan2*, Shaukat Ali3, Muhammad Khan1, Farah Rauf Shakoori1, Javed Iqbal Qazi1 and Muhammad Abrar Yousaf1
...n showed highest tannase activity. The results depict utilization potential of low cost substrate (corn leaves) to reduce the production cost of tannase.

...

Dalia Zaafar1*, Heba M.A Khalil2, Soha Hassanin3, Mohamed R. Mousa4, Mona G. Khalil1 

...ide the higher apoptotic activity. Furthermore, Cis+Pio HD reduced the expression of PCNA and HIF-1 and increased the expression of PPARγ, which improved the histopathological changes. Conclusion: Pio possesses ESC-specific anticancer abilities. However, more research is needed before it can be used as an adjuvant agent to boost the therapeutic efficacy of chemotherapy in the treatment of many types of cancer.

Keywords | Pioglitazone; Cisplatin; ...

Noor Rahmawati, Alfi Rumidatul* and Sopandi Sunarya

...acterial and antioxidant activity. The method used in this study was to ferment endophytic fungi from gall rust sengon in different media, namely PDB, PDB plus sengon wood powder, and PDB plus yeast, for 9 days, followed by extraction using ethyl acetate solvent and testing of antioxidant and antibacterial activity. The DPPH radical was used to measure antioxidant activity, and Bacillus su...

Ali I. Al-Ameedi1, Zahraa M. Ayad2*, Wed Abbas Mohammed3, Salim K. Hajwal4

...ascertain the protective activity of the plant extract, the mitotic index and blast index are also assessed. The results showed that the exposed group (T1) had a significantly lower mitotic index (the number of cells in mitosis per 1000 bone marrow cells) than the control group (which only drank distilled water). These results showed a significant decrease (p>0.05) of the mitotic index of (the T1) group that received hydroxyurea orally compared with the con...

MARIUM ASLAM, MUHAMMAD JAVED, FAIZA AMBREEN* & FARIHA LATIF

...f zinc on the peroxidase activity in the liver and kidney of Catla catla. To check the concentration based effect, C. catla were exposed, separately, to 96-hr LC50 of zinc and its sub-lethal concentrations viz. 2/3rd, 1/4th and 1/5th of LC50 for 30 days at constant laboratory conditions. After 30-day, the fish were sacrificed and their liver and kidney were analyzed for peroxidase enzyme activity. Change in
TAHIR MEHMOOD*, ANUM AFZAL, ABDUL KARIM, MUHAMMAD ASHRAF SHAHEEN &
HINA ARSHAD
...y was to appraise the bioactivity of compounds using TFC (total flavonoid content), DPPH scavenging activity, reducing power assay and ABTS (radical scavenging activity) of different solvent extracts, from Citrus limon (unripe and ripened) peels. In unripe peels the total flavonoid contents, DPPH radical scavenging activity, ABTS radical scavenging

AISHA, MUHAMMAD ASAM RAZA* AND UMME FARWA

...ed for enzyme inhibition activity through spectrophotometer and suggested that compounds may be helpful in the medicinal field. Compound 2 exhibits more inhibition against BChE (67.7%) while compound 1 showed maximum inhibition of α-glucosidase (65.1%). Theoretical study i.e. docking of the prepared compounds was also related to experimental work. In-Silico ADMET study of both compounds exhibited various therapeutic properties, which depicted that they a...
 
 SADAF SARFRAZ1*, SAFDAR AMEER1, REENA AMBREEN1, SHOMAILA SIKANDAR 2, SHAISTA NAWAZ3 AND YASIR SALEEM
...his study, antimicrobial activity of cinnamon was estimated using well diffusion method against various bacterial and fungal strains. As shown by the findings of the present study, Cinnamon oil is found a potent antibacterial agent against all microbes used. Additionally, it was found that cinnamon samples collected from Sri Lanka has the highest oil content (3.1%), followed by China (2.8 %) and India (1.9 %), where all tests were standardised using fixed oil ...
 
 ANSA KHALID, UZMA HAMEED* AND IKRAM-UL-HAQ 
...n as it gave the maximum activity. Among the 10 different fermentation media screened for enzyme production, maximum dextransucrase activity (9.96 U/ml) was obtained by bacterial strain IIB-C9 in fermentation medium M6 comprising (yeast extract 15 g/L, sucrose 40 g/L, and Na2HPO
 
 ANSA KHALID, UZMA HAMEED* AND IKRAM-UL-HAQ 
...n as it gave the maximum activity. Among the 10 different fermentation media screened for enzyme production, maximum dextransucrase activity (9.96 U/ml) was obtained by bacterial strain IIB-C9 in fermentation medium M6 comprising (yeast extract 15 g/L, sucrose 40 g/L, and Na2HPO
 
 SYED ALI RAZA1, MUHAMMAD WASEEM MUMTAZ2*, AYOUB RASHID CH1, ABDUL WAHEED1, JAMES WILLIAM3 & MUHAMMAD ARSHAD
... inhibition of enzymatic activity of pancreatic lipase. The 60% ethanolic leaf extract exhibited maximum pancreatic lipase inhibition of 54.55 ± 0.72% but lower than standard drug orlistat (66.65 ± 0.68%). Findings explored the hidden antioxidant and pancreatic lipase inhibitory potential of Conocarpus lancifolius that may be exploited for naturopathic treatment of obesity and functional food development with anti-obesity attributes. ...

Ubaida Hussain1,2*, Amtul Jamil Sami1*, Shazia Rafique3*, Muhammad Idrees khan3 and Ahmad Ali Shahid3

...een tested for cytotoxic activity. Colorimetric analysis was done to determine the vitality of HepG 2 cells for 24 h after treatment with methanolic seed extract and minimum inhibitory concentration was calculated. HepG2 cell were transfected stably to express nonstructural proteins NS3 and NS5A of HCV 3a genotype. Western blot and RT PCR confirmed stable protein expression. Immunofluorescence assay was done to check subcellular localization of these nonstruct...

Chenchen Liu1,2, Tong Wang1, Muhammad Khan3*, Xiaolin Cui2 and Yongming Li1,2*

...wn to exhibit anticancer activity against a series of human cancers through multiple mechanism. However, the anticancer effects of ALT against ovarian cancer remains unknown. Here, we report that ALT inhibits growth and induces apoptosis in parental and cisplatin-resistant ovarian cancer cells. Growth inhibitory effects of ALT are evident from CCK-8, Edu, and colonogenic assays. The molecular mechanism associated with induction of apoptosis includes ROS genera...

Zhe Lin1, Yumo Li1, Yuchen Wang1, Yuechen Li1, Ke Pei1, Guangfu Lv2, He Lin1* and Zhun Yu3*

Yang Hu, Jingxin Ding, Beilei Xu, Xiangming Sun, Guoyu Li, Hui Song, Zheng Zong and Wenlan Li*

...vo and its estrogen-like activity, and reveal its direct acting substances in the body, in this study, 30 female Wistar rats were orally administered with TGs, and serum fingerprints of blood samples collected at 10 different times were established by UPLC-Q-TOF-MS analysis. The estrogen-like activity of TGs was evaluated by determining the proliferation rate of Michigan Cancer Foundation-7 cells. The spectrum-effect relatio...

Doaa H. Assar1, Rasha A. Al-Wakeel2, Zizy I. Elbialy3, Mahmoud M. El-Maghraby4, Helmy K. Zaghlool5, Adel A. El-Badawy4, Abdel-Khalek E. Abdel-Khalek6*

... significantly decreased activity of aspartate and alanine transaminases (AST and ALT), triglycerides, cholesterol, low-density lipoproteins (LDL), very-LDL, and urea. Semen variables including semen volume, and percentages of sperm motility, livability, and abnormality as well as concentration and output of sperm cells were significantly by SPL. In serum and seminal plasma, glutathione, superoxide dismutase, catalase, and glutathione peroxidase significantly ...

Hanaa M. Abdelkhalek1, Hanan E. Nagib1, Randa S. Elias1, Saad S. Mansour1, Walid S. Mousa2*

...recognized a synergistic activity between amikacin and norfloxacin against all P. areuginosa isolates. The mPCR was an efficient tool for detection of virulence genes (exoT, toxA, oprL, and isaI) at 152, 396, 504, 606 bp respectively. In addition, all the P. aeruginosa were found to carry the resistance genes (qnrS, qnrA, aadB). The combination of norfloxacin plus amikacin suppressed the resistance pattern P. aeruginosa isolates. Therefore, their combination s...

Safaa Rhaimi1, Sara Brikat2, Mouloud Lamtai2*, Mohammed Ouhssine1

... produce neuroprotective activity in female rats.
 
Keywords | Herbal medicine, Acute toxicity, Salvia officinalis, Anxiety, Depression, Memory, Rats, Phytotherapy
...

Anhar Ibrahim Elhanafy*, Amr Mohamed Mousa, Amaal Mohamed Kamal 

...s whilst it enhanced GPx activity, SOD, IgG and IgM, compared to control. Furthermore, BV treated does have significantly higher levels of C3 and C4. Conversely when compared to control, significant reduction in IL-1β, IL-6 and TNF-α was recorded. In addition, BV treatment led to a significant improvement in T3 and T4 concentrations as detected by the radioimmunoassay technique. Results suggested that BV can be an effectual and safely naturalistic i...

Oussama Zghari*, Mouloud Lamtai, Sofia Azirar, Mohamed Yassine El-Brouzi, Hajar Benmhammed, Aboubaker El-Hessni, Ali Ouichou, Abdelhalem Mesfioui

...ide (NO) and reduced the activity of superoxide dismutase (SOD) as well mediates brain damage in CA3 hippocampal area. These alterations were reversed by MEL. It can be concluded that, by exerting its properties against the oxidative action of this metal in the hippocampus, MEL may play a potential role in protecting against the behavioral and histopathological alterations induced by Al.
 
Keywords | Aluminum, Melatonin, Neurobehav...

Hala A. Amin1; A. Barakat2; A.A. Abou Zeid1

...tein showed comparable reactivity in the serological detection of CTV. This antiserum could be used at dilution or 1: 10.000 at the detection stage in an indirect ELISA (IDAS-ELISA) and was efficient for trapping the virus in standard ELISA. These polyclonal antibodies reacted with a wide range of CTV isolates from different Egyptian geographic sources, and or different biological properties.

...

Waheed Khan1, Muhammad Ajmal Khan2, Bakhtawar Khan1*, Aftab Amin3, Muhsin Ali4, Awais Farid, Ali Hazrat5 and Muhammad Yahya5

... of insulin synthesis or activity. At present, the existing diabetes mellitus drugs have many adverse reactions. Therefore, it is needed to investigate novel methods to improve DM treatment. Thus plant-based management could be a possible antidiabetic strategy. The objective of the most recent study was to assess Verbascum thapsus’s ability to combat hyperlipidemia and diabetes. Mice were given an intraperitoneal injection of alloxan (150 mg kg-1, b.w.) ...

Fang Chen

...ignificant effect on the activity of mutant 3’UTR luciferase of PTEN (P>0.05). The miR-4728-3p inhibitor group had less cell migration and invasion, and its apoptosis rate increased (P<0.05). The abnormal expression of miR-4728-3p mediated the apatinib resistance of SCLC by targeting PTEN and regulating PI3 K/AKT pathway.

...

Shaimaa A.Tawfik2,3, EL S.T. Awad1*, Hoda O.Abu Bakr1, Amira M.Gamal-Eldeen4, Esmat Ashour2, Ismail M.Ahmed1  

... G4 CSO/DOX. Antioxidant activity, histopathological examination, immunohistochemical analysis of CYP3A4, MRP-1, and c-MYC proteins and expression of miRNAs were assayed. Results: Findings indicated that CSO treatment led to a suppression in hepatotoxicity, nephrotoxicity and cardiotoxicity induced by DOX in male albino rats evidenced by a significant enhancement in the activity of ALT, GGT, LDH, AST, also creatinine an...

Muhammad Asim Bhutta1,2*, Amna Bibi2, Nadia Hussain Ahmad2, Sadia Kanwal2, Zarmeena Amjad1, Hafeez ur Rehman3, Umar Farooq3, Muhammad Nouman Khalid4 and Syeda Fiza Nayab5

...dependent photosynthetic activity restricts the consumption of electrons produced in the early photoreactions, which appears to be the principal cause of photoinhibition by visible light. There is a chance that excessive photosynthetic electron transport could lead to an overabundance of reactive oxygen species (ROS). Reactive oxygen species such as H2O2 and O2, that develops in photosystem II as a result of exposure to intense light, start to damage electron ...

Rahma Boukarine*, Leila Hamdi and Kamel Khelili

...se in GSH levels and GPx activity accompanied with an increase in MDA levels were noted due to the exposition of xylene. However, animals that received ESAE with xylene (REX1 and REX2) showed an adjustment of these perturbations, by a significant decrease in the levels of AST, ALT, ALP, urea, uric acid, creatinine and MDA. As well as an increase in GSH levels and GPx activity compared to X1 and X2 groups. The histological pr...

Nitya Salsabila, Djalal Rosyidi, Agus Susilo* 

...t different times on the activity of water (Aw), water, fat, ash, carbohydrates by difference, and organoleptic quality (color, texture, aroma, and taste). The research material used was jerky made from duck meat with the addition of coconut shell liquid smoke and spices such as salt, coconut sugar, garlic, galangal, coriander and tamarind. The method used was a laboratory experimental method using a completely randomized design (CRD) with 6 treatments and 4 r...

Muhammad Awais Ahmad1, Mudssar Ali1*, Asif Sajjad2 and Shafqat Saeed1

...ors, abundance, foraging activity and most importantly pollination efficiency in a single visit in terms of reproductive success parameters (head size, florets per head, seed count/head, seed mass/head and seed mass of 1000 seeds). The pollinator’s community was composed of 06 Hymenoptera, 03 Diptera and 02 Lepidoptera species. It was found that the total abundance of a solitary bee Pesudapis oxybeloides was higher followed by a honey bee, Apis mellifera...

Nawfal Hammadi Jasim1, Yasmeen Jassim Mohammed2 , Jala Amir Salman Alahmed1, Majdy Faisal Majeed3* 

...f attention deficit hyperactivity disorder is Methylphenidate hydrochloride (MPH) or Retalin (the commercial name) . Objective: The effects of MPH on adult male rats have been evaluated in this study. Materials and methods: receiving an oral dose (2 daily MPH doses), represented by Group 1 (5 mg/kg/day in a 5% glucose solution), Group 2 received daily dosages of methylphenidate in escalating amounts (5, 8, 12, and 16 mg/kg/day in a 5% of sucrose solution), as...

Saima Mehar1, Amtul Sami2 and Erum Iqbal3*

... the maximum nematicidal activity in egg hatching (15%±2.10) of M. javanica, followed by N. sativa (Ether), 22.33±6.86%, at the lowest administered dose of 0.25 % concentration. After 72 hours of treatment, C. cyminum (MeOH) and N. sativa (BeOH) had a non-significant difference in nematotoxic impact (90.0±10.3, 88.0±7.2 mortality %, respectively) in 1% concentration. According to decreasing order, MeOH>BuOH>Chloroform>ether...

Rukhsana Anwar1*, Muhammad Usman Khalil1 and Kanwal Ashiq1,2

...-acute anti-hypertensive activity of a methanolic extract of Colebrookea oppositifolia 250 mg/kg were studied for 14 days in rats. Captopril (20 mg/kg) was given as a standard control. Non-invasive blood pressure (NIBP) monitoring technique was used to assess the blood pressure of rats. The frequency of hippuric acid synthesis from the hydrolysis of Hippuryl-L-Histidyl-L-Leucine was utilized to calculate angiotensin-converting enzyme (ACE)

Jawad Ali1,*, Samiya Rehman1, Aqsa Aslam1, Fouzia Tanvir2, Rida Liaqat1, Muhammad Ahmad1, Aamir Riaz1, Muhammad Shafique3, Hassan Ali1 and Amjad Ali1

... Free radical scavenging activity and total antioxidant activity experiments were performed on the samples using the DPPH and Phosphomolybdenum methods. Results shows leaves extract from Mianwali has the highest total antioxidant capacity while stems collected form the Sargodha has highest free radicals scavenging ability with values of 47.60± 3.00 Vit C equiv mg/g DW and 50.00± 3.00 IC50 value. 

...

Imtiaz Khan1*, Bashir Ahmad1, Ahmad ur Rahman Saljoqi1, Shah Alam Khan1, Javed Khan3 and Muhammad Azim Khan2

...2020-2021) with its peak activity in the month of August. Significantly, positive correlation was recorded between P. perpusilla (eggs clusters and nymphs/adults) population infestation and average abiotic factors (temperature, humidity and rainfall). The correlation between leaf length and leaf width with P. perpusilla (eggs clusters and nymphs/adults) was significantly positive, the correlation of P. perpusilla (eggs clusters and nymphs/adults) with cane len...

Hamdi Mayulu1*, Endang Sawitri2

... DPPH radical scavenging activity was 58.5 µg/mL at 21 days of incubation (T3). This indicated that black garlic has broad potential to become a natural feed additive suitable for livestock production in line with the development and progress of science and modern technology.
 
Keywords | Black Garlic, Bioactive Compounds, Antioxidants, Feed Additives, Livestock
...

Indri Juliyarsi1*, Sri Melia1, Rizki Dwi Setiawan1, Deni Novia1, Lailatul Anshor2, Tomi Candra2 

...es of color, antioxidant activity, and sensory properties of edible films made from whey with the addition of antioxidants from Rosella calyx extract (Hibiscus sabdariffa L). The edible film was prepared with the addition of four different levels of rosella extracts (0, 0.2, 0.4, and 0.6%). The addition of rosella calyx extract led to a significant difference (P<0.05) in color (redness), antioxidant activity, and color se...

Amr N. El-Shahat1*, A.M. Abdul Azeem1 and Mohamed H.M. Abd el Megid2

...ties such as antioxidant activity, anti-inflammatory activity and prevention of cardiovascular diseases. The present study aims to investigate the effectiveness of bay leaf extract (BLE) in protection against high cholesterol diet (HCD) induced hypercholesterolemia. About thirteen compounds of essential oils were identified by GC/MS analysis including 1.8-cineole, Linalool and sabinene which represent the main volatile oils ...

Sarwat Yousuf1, Shaista Emad2 , Mohammad Misbah ur Rehman3, Zehra Batool4, Sara Qadeer5, Yousra Sarfaraz1, Sheeza Sheikh1, Sana Sadaf6 and Tahira Perveen1,*

...divulge their biological activity is an area of great interest. Citrus lemon is traditionally used as an antioxidant, antibacterial and anti-inflammatory agent. This study intended to determine the potential role of lemon peel oil in neurobehavioral function and oxidative stress. Rats were treated with lemon peel oil at a dose of 0.7, 1.4, 2.1, 2.7, 3.5 g/kg for 14 days. Results showed that lemon peel oil at low doses has antidepressant and anxiolytic

Yajuan Zheng, Qiuping Mo, Hongchao Tang, Qinghui Zheng and Dandan Guan*

...stern blot. The relative activity of the above three types of cells after 24 h of culture was detected by CCK8 assay. The migration ability of the cells was analyzed by the cell scratch test, and the invasive ability of the cells was analyzed by the transwell detection. Construct LGR5-knockdown, LGR5-overexpressing and LGR5-ΔC-overexpressing (lack of C-terminal tail) human colon cancer LoVo cell lines. The mechanism of the reaction between LGR5 and IQGAP...

Amina Rahat1, Zahin Anjum1*, Sehlina Zehra2, Fatima Umal Baneen3 and Rabia Chishti1

...ignificant antibacterial activity. Additionally, Different fractions of the A. sativum, P. ovata, N. sativa were prepared anad analyzed for antibacterial, insecticidal and antifungal activities. Based on the results of this study, it can be concluded that almost all the plant extracts showed potential antibacterial, insecticidal and antifungal activities against different microbes.

...

Saqib Mehmood1, Bushra Allah Rakha1*, Muhammad Sajjad Ansari2, Ali Akhter1, Nadeem Munawar1 and Tariq Mahmood1

...ach study sites, maximum activity (P <0.05) of rodents was recorded inside of the crop field (1.75 ± 0.02 ha-1) in relation to the boundary (1.46 ± 0.04 ha-1) of the field. 6.20%, 1.30% and 0.77% crop damaged was calculated at maturity, tillering and sowing stage respectively. Ecological manipulation has resulted in remarkable reduction (P<0.05) in the density of rodents in treated areas compared to reference sites. Present study concluded ...

Abdulaziz A. Alaqil*

...ione peroxidase (GHS-px) activity, respectively. The general linear model procedure with one-way analysis of variance (GLM-ANOVA) was used to analyze the data. The results showed a significant (P<0.05) increase in the BT, H/L ratio, MDA, and CORT, and over-expression of HSP70 in the hens of LPS group. Also, significant (P<0.05) impairments were perceived in the feed consumption and conversion, and in the egg weight and production rates. In contrast, the ...

Isatay Tusupovich Jakupov, Gulzhan Tursunovna Yeszhanova, Gulnur Kurbanalievna Mamytbekova* 

...heir pharmacotherapeutic activity and use for the treatment of endometritis in cows. A total of 270 cows were examined by clinical methods after calving, of which 45 cows showed signs of acute endometritis. Subsequently, the bacterial background of uterine mucus in sick cows was investigated and St. pyogenes, E. faecalis, and E. coli were isolated. For the complex treatment of acute postpartum endometritis, the cows of the experimental groups were treated with...

Altaf Ur Rahman1, Muhammad Ajmal Khan2*, Ali Hazrat3, Awais Farid4, Muhammad Yahya3* and Inam Ullah5

...itative test antioxidant activity of the methanolic fraction of C. jacquemontii at 250 µg/ml revealed the best antioxidant potential when the DPPH concentration of 150 µg/ml was used. The result showed that extract had a significant effect on antioxidant activity. Therefore, the present study supports the effectiveness of methanolic leaf extract of C. jacquemontii in traditional medicine and may be investigated f...

Abdur Rauf1*, Farooq Jan1, Muhammad Qayash2, Zia-ul-Islam3, Rizwanullah1, Ikramullah Khan1, Muhammad Shuaib4, Muhammad Khalid5 and Samrin Gul6

...st S. aureus, a moderate activity (13.31±0.64), (15.43±0.52), (14.35±0.64), (11.34±0.50), (13.47±0.55), (14.21±0.67), (9.53±0.51), (15.32±0.53), and (2.15±0.65) against E. coli, B. subtalus, and M. leutues. A 15mg/ml crude extract of H. eichwaldii exhibited the lowest potential (2.15±0.65) against M. leutues, while a 20mg/ml extract showed a very high potential against A. niger and A. flavus...

Muhammad Adeel Farooq1, Shaukat Ali1*, Ali Hassan1, Rida Sulayman1, Muhammad Ahsan Kaleem2, Hafsa Shahzad1, Muhammad Summer1, Arooj Latif1, Tahreem Tanveer1

... Optimum α-amylase activity was measured at 40±0.5°C, pH 7.0±0.2 and 1% starch solution by BSAA-25 (338.6±11.0 U/mL) and BLAA-25 (326.8±6.4 U/mL). A considerable increase was seen in the biosynthesis of α-amylase from mutant strains of B. subtilis and B. licheniformis using agro-waste as substrate.  
 
Novelty Statement | This scientific study presen...

Farha Deba1, Rubina Nelofer2 and Muhammad Irfan1*

...d the highest keratinase activity at neutral pH 7.0, with 1% inoculum size, 1% substrate and after 72h of the incubation period. This current study revealed that these isolates have ability to be used in many biotechnologies prospective applications like in hydrolysis of keratin-containing substrate. Recently, it has been extremely beneficial and a major priority to use microorganisms for the enzymatic destruction of keratin waste material rather of various co...

Walaa I. Mohameden1, Haidy G. Abdel-Rahman2, Ibrahim M. Hegab3* 

...ditions, and antioxidant activity, as well as it has a minimizing influences on TNF-alpha and MMP-9.
 

...

Lianci He1, Dingxi Bai2, Chenxi Wu2, Yizhu Zhong2, Shi Chen2, Xinru Bao2, Jing Gao2*, Chaoming Hou2*

...dy weight, fatigue time, activity and mobility, and mRNA and protein levels of interleukin-1 beta (IL-1β), tumour necrosis factor alpha (TNF-α), transforming growth factor β-activated kinase 1 (TAK1), TAB, IκB kinase (IKKα), IκBα, NF-κBp65 and cyclooxygenase-2 in the serum were measured. Compared with the CON group, the CFS group had decreased weight and decreased activity and mo...

Rusul Adnan Dawood, Hasan F.K. Alghetaa*

...valuate the redox system activity. Furthermore, peritoneal exudate was collected to determine the population of infiltrating cells by using trypan blue dye. Analyzed data revealed that there was renal dysfunction represented by significant (P<0.05) increase in blood urea of HD and HR groups in comparison with control group. Total antioxidants were significantly (P<0.05) higher in the blood of HR group than all others. Moreover, peritoneal exudate showed ...

Abdel-Khalek El-Sayed Abdel-Khalek1*, Abdelaziz M. Sakr2, Wael M. Nagy2, Hesham S. Abou-Serie2, Entesar Z. Eliraqy2

...and superoxide dismutase activity, and decreased percentage of apoptosis, early apoptosis, necrosis, and malondialdehyde level; most favorable results were recorded with PEE2. The foregoing results indicated that supplementation of Tris-semen extender with propolis ethanolic extender at a level of 8 mg/ml increased the functional activity of spermatozoa, decreased sperm apoptosis, and necrosis, and improved the antioxidant s...
Hung Phuc Nguyen1*, Doan Van Thuoc2*, Nguyen Thi Trung Thu1, Huong Tran Thi Mai3, Nguyen Tran Khanh Hoa1, Nguyen Thi Tuyet Nhi1, Nguyen Phuong Thao1, Tran Thi Loan2 and Nguyen Thi Huyen My2
...reduced digestive enzyme activity, bile juice secretion, and nutrient ADCs. These parameters of the experimental fish were markedly improved by feeding with FSR35D and FSR50D, and no statistical differences were observed between FSR35D- and FMD-fed fish. The results of the current study indicated that SR interfered with digestive enzyme activity, bile juice secretion, nutrient ADCs, and growth and feed performances. The enha...
Iram Liaqat1*, Noor Muhammad1, Muhammad Mubin2, Najma Arshad3, Tehreema Iftikhar4, Sumera Sajjad5 and Farzana Rashid5

Weijun Chen1*, Shiyang Gao1, Ping Sun1, Xiaohui Sun2, Yongbin Wei1, Jingyang Chen1 and Jialong Chen1

...MDA) content, decreasing activity levels of antioxidant enzymes and contents of reduced glutathione (GSH). Furthermoure, diet HF significantly decreased the mRNA expression of nuclear factor erythroid 2-related factor 2 (Nrf2) and heme oxygenase-1 (HO-1), and simultaneously increased the mRNA expression of tumor necrosis factor α (TNF-α), interleukin-1β (IL-1β), and IL-6 in liver of common carp compared to control diet (P<0.05). Howeve...

Lili Zhao1, Fan Zhao1 and Yaping Jin2*

...oliferation and adhesion activity, while increasing invasion activity. The secretion of estradiol and progesterone was also dramatically decreased after Grp78 knockout. Our results strongly suggest that GRP78 plays an important role in maintaining the normal functionalities of GTCs.

...

Sherein H. Mohamed1, Soad El Naggar2*, Ayman A. Hassan3, Mohamed A.M. Mousa3, Mohamed M. Basyony3, Mohamed F. Sadek3, Mohamed A. A. Ahmed4, Saadia M. Hashem5 

...nd increased antioxidant activity.  It was concluded that these extracts as a natural biologically active substance improved growth performance, feed digestibility, antioxidant activities and immunity, allowing growing rabbits to produce high quality meat of growing rabbits. 

...

Mudawamah Mudawamah1*, Sumartono Sumartono1, G. Ciptadi2, E. Susanto3, Y. Hartoyo4, L. Affandhy5,6

... healthy condition (good activity), good appetite with feed given in the form of concentrate (2% of body weight), and forage (10% of body weight). The results showed that morphology, physiology, and total protein did not show a significant relationship (p>0.05) to differentiate broodstock in a single or twin brood in Sapudi sheep or their crosses, except for Suffas sheep. Total protein could show the difference between twin lambs having total protein > 6...

Bushra Allah Rakha1*, Farah Qayyum1, Muhammad Sajjad Ansari2, Ali Akhter1, Komal Shakeel1, Javeria Batool1, Faryal Akhtar1 and Sehrish Hina1

...corded while no breeding activity was recorded during month of February. It is concluded that (MHNP) is a favorable site for breeding activity of white-cheeked bulbul.

...

Amistu KU1,2*, Monahan FJ2, Wims P2, Yonatan KY1 , Fahey AG2, Takele TA3 

...d crop-livestock farming activity as a source of income. The major feed resources for beef cattle fattening during the dry season are Desho grass (30.7%), hay (15.0%), and crop residues (14.7%) as basal diets, whereas for the rainy season fatteners almost fully depend on natural pasture (97.7%). However, fatteners use corn/fresh maize (87.7%), coffee leaf boiled together with water (44.4%), haricot bean (40.5%), cassava root (28.8%), mixed concentrates (21.6%)...
Burarah Arooj1, Zeeshan Mutahir1, Moazzam Ali1, Mohsina Akhter2, Malik Siddique Mahmood1, Arslan Hamid3 and Mahjabeen Saleem1*
...chitinase showed optimum activity at 60°C and pH 5.5 with colloidal chitin breakdown. Enzyme showed stable residual activity within pH range of 4.5–6.5 and >70% thermal stability upto 60°C for 2.5 h. The activity of chitinase increased in the presence of Mn+2, SDS, and methanol. Chitinase has Km and Vmax values of 2.287 mg/ml and 6.784 µM/min, respectively, towards c...

Omar Berkani1*, Souheila Slimani2, Nora Sakhraoui3 and Cherif Abdennour1

... photoperiod, the sexual activity of the control group lasted for 06 weeks, characterized by a significant growth in the testicular volume, followed by spontaneous gonadal regression up to week 10. Azoospermia in control birds was noticed, with a significant increase in FT4 level and a fall of flying feathers in the 8th and 10th weeks, which assert the testicular regression. Compared to the control, CYP1 and CYP2 increased the testicular weights significantly ...

Saad Tahir, Nadeem Ahmed*, Mohsin Ahmad Khan, Muhammad Akram, Rabia Abbas and Kausar Malik

... estimate the biological activity of HSA-SK. For half-life estimation, proteolytic and thermal stability of HSA-SK was also checked.

...
Rabail Hassan Toor1,3, Raazia Tasadduq2, Jane B. Lian3, Janet L. Stein3, Gary S. Stein3 and Abdul Rauf Shakoori1*
... for its anti-osteoclast activity. Upon RANK-L induction of RAW264.7 cells to differentiate into osteoclasts, we found 10ng/ml CQ-H as most efficacious concentration for inhibiting osteoclastogenesis with 57.8% inhibition of TRAP activity. Whereas, in comparison 20ng/ml RSV showed 49.9% inhibition of TRAP activity. Expression of osteoclast marker genes such as NFATc1, ACP-5, CTSK, MMP-9 an...

Di Zhou1, Qingmeng Long1*, Rong Yang1, Xiaoshan Tan1, Jun Li1, Mingyan Tang1, Zhonghai Zhao3, Ye Ao2, Zhinan Zhou1 and Changxue Chen1

...otein binding, catalytic activity and cell proliferation. Moreover, these DEGs were enriched in the categories of signal transduction, reproductive system, endocrine system and cancer-related pathways and linked the cGMP-PKG, cAMP, TGFβ and mTOR signaling pathways to reproductive performance. We verified these results using qRT-PCR for 9 up-regulated (AMH, CYP19A1, FOXL2, FSHR, GATA4, INHBA, LHB, LHX9 and ZP3) and 9 down-regulated (CNOT1. DMRTA1, GHRHR, H...

Salma Jameel Askar 

...f cyclooxygenase (COX-1) activity by these drugs has been associated with substantial side effects, beetroots act as a medicinal herb in the treatment of hematological disorders, and act as antioxidant. The aim of this study was to examine the effects of sub-chronic exposure to meloxicam, nonsteroidal anti-inflammatory drug, on hematological alterations and liver functions parameters in albino male rats and to determine the effects of Beetroots ethanolic extra...

Wei Fang1,2,3, Jiawei Hong1,2,3,4, Zhengyi Fu1,2,3, Jing Hu1,2,3, Gang Yu1,2,3, Zhenhua Ma1,2,3* and Humin Zong5*

...s, binding and catalytic activity; COG analysis showed that DEGs was mainly related to posttranslational modification, protein turnover, chaperones, intracellular trafficking, secretion, vesicular transport, transcription, amino acid transport and metabolism; KEGG analysis showed that DEGs was mainly related to cardiac muscle contraction, renin-angiotensin system, adrenergic signaling in cardiomyocytes, oxidative phosphorylation; The distribution types of SSR ...

Aryaf Mahmood Sabea1*, Majida A. Al-Qaiym2 

...e in reestablishment the activity of lymphocytes and macrophages. In conclusion, the present study demonstrated that thyroid hormones had regulatory role for innate and adaptive, and in order to reach the best result of treating hypothyroidism and improving the activity of the immune cells , selenium must be given with the Levothyroxine 

...
Guo-Hai Wang1, Ji-Feng Long2, Li-Juan Wei3, Zhi Qin2, Wei Yao4, Chuang-Bin-Tang1* and Qi-Hai Zhou4*
...">Understanding wildlife activity and the temporal niches of animals is fundamental in revealing the mechanism of niche differentiation among sympatric species and the coexistence of such species communities. However, there is no clarity on whether the activity patterns of the sympatric species red-bellied squirrels (Callosciurus erythraeus) and Northern tree shrews (Tupaia belangeri) overlap; knowledge on the coexistence me...
Mohamed I. El-Katcha1, Mosaad A. Soltan1, Seham M. El-Kassas2*, Mahmoud M. Arafa3, El-Sayed R. Kawarei 3, Karima M. El-Naggar1*
...m glutathione peroxidase activity compared with CuO (P < 0.05). Moreover, serum lipid profile was significantly altered as triglycerides concentration was increased while total cholesterol was reduced in birds received organic and CuO-NPs. So, the organic or Nano forms of Cu could be used as safe alternative sources in layer diets replacing the inorganic Cu without compromising their productive performance.

...
ZAMARA MASOOD1, FAROOQ SALEEM1, SARFRAZ AHMAD2, TALHA JAMSHAID3, IMRAN WAHEED4,
MUHAMMAD AZEEM1, UMAR FAROOQ GOHAR5 & HAFIZ MUHAMMAD ARSALAN6, 7*
... promising antimicrobial activity
in terms of zone of inhibition against selected bacterial strains, both Gram
positive and Gram negative i.e. from 1.33 mm to 25.66 mm and against
fungal strains i.e. from 1.33 mm to 24.33 mm. These findings suggest that
the different parts of R. laetus exhibiting different biological activities and
could be used as a promising source of novel drugs.
...

Orooba Mohammed Saeed Ibrahim1*, Rawaa Saladdin Jumaa2, Nibras Zeyad Yahya1 

...onia. The antibacterial activity of fruit juice extract on bacterial strain was determined using macro-broth dilution, agar well diffusion methods and time kill curve. Results revealed that the used juice extracts were variously bacteriostatic and bactericidal against the examined bacteria depending on concentration. Phytochemicals analysis indicated the presence of alkaloids, phenol, saponins, flavonoids, tannins, and glycosides. The test organism was more s...
Fariha Javaid1*, Zahoor Qadir Samra1, Madeeha Shahzad Lodhi1,2, Aroosha Hussain1 and Gulnaz Pervaiz1
...M has the highest enzyme activity at 23.5 U/ml as compared to crown leaf (11.7 U/ml) and peel (19.5 U/ml). The specific activity of leaf, peel, and stem BRM was determined 0.8, 1.2, and 1.4 U/mg, respectively. Total protein content was 660 mg, 810 mg, and 865 mg from leaf, peel, and stem samples. The percentage yield of BRM was determined in the range of 60 to 93 % from these waste parts of the plant. This study achieved 4, ...
Ummul Firmani1,3, Rahmi Nurdiani2, Arning Wilujeng Ekawati2 and Happy Nursyam2*
...lytic assay, synergistic activity, hemolytic activity, and antagonistic activity. The results showed that there were several types of bacteria found in the digestive tract of milkfish. One of these bacteria could produce an amylase enzyme with an amylolytic index of 5.16, identified as Bacillus paramycoides. This bacteria also synergized with other bacteria and did not have hemolytic

Baoxuan Nong1,2, Biqiu Wu3, Anlong Xu2, Wenai He2 and Yongfu Qiu2*

...edbox screening, feeding activity via measurements of honeydew excretion, and insect development by counting the number of hatched nymphs. Two resistance varieties N22 and OB677 were crossed with susceptible line 9311 to develop mapping populations, which were applied to map the resistance genes/QTLs. In the results, rice variety PTB33 showed high resistance to both brown planthopper (BPH) and WBPH, varieties N22, RBPH327, and OB677 showed moderate resistance ...

Al-Moataz Bellah Mahfouz Shaarawy1, Wael Mohamed Wafa1*, Ashraf Ali Mehany1, Reda Abdel Samee Ahmed Rezk2, Shereen Kamal Genena1, Mohamed Hamada El-Sawy1 

...isol and creatinine, and activity of AST and ALT in serum were significantly increased (P<0.05, 0.01 and 0.001), while TSH, T3, T4, total protein, glucose, cholesterol, Ca, P, Na, and K, ALP activity, and milk yield significantly decreased (P<0.05, 0.01 and 0.001) in summer than in spring in Friesian and crossbred cows. In summer season, Friesian cows showed significant increase (P<0.05, 0.01 and 0.001) in RR, PR, c...

I Nyoman Sumerta Miwada1*, I Nyoman Sutarpa Sutama1, Agus Susilo2

...evaluate the antioxidant activity, textural attributes and hedonic properties of cheese resulting from Moringa leaf extract fortification. Moringa leaf extract was fortified in the five treatment groups, 1000 ml each with different concentrations, namely 0% (P0); 2% (P1); 4%(P2); 6%(P3) and 8%(P4). The research method used one-way analysis of diversity (at p<0.05) and continued with the Duncan test using the SPSS version 25 system. The results showed that i...

Raed Hussein Salih Rabee1, Yahya Sabah Abdulameer1, Walla Farhan Obed1, Noor R Abady1, Adnan Mansour Jasim1*, Firas Hussein Albawi1, Mohammed Jasim Jawad2, Ahmed Samir Abukhomra3

...udy confirmed inhibitory activity of Cytochrome P450 3A4 (CYP3A4) and P-glycoprotein (P-gp) an enzyme responsible for the metabolism of antibiotics. Additionally, berberine demonstrated antibacterial effects against E. coli, as well as anti-inflammatory and antioxidant properties. Furthermore, histopathological examination of the intestinal broiler received BBR showed improvements and restore tissue near to normal.
 
Keywords | Ene...

Fatemeh Beheshti1, Maliheh Safavi2, Mohammad Reza Akbari Eidgahi1,3, Parviz Kokhaei4, Mehdi Vazirian5 and  Ali Akbar Shabani1,3*

Hafiza Mehwish Iqbal1, Salman Khurshid1*, Saqib Arif1, Qurrat-ul-Ain Akbar1, Saba Iqbal2, Shahid Yousaf3, Kainat Qureshi1, Abdul Karim Khan5, Abdul Ahad6, Aqeel Ahmed Siddique4 and Neelofar Hamid7

...%has maximum antioxidant activity in O. basilicum whereas, in S. asoca and M. koenigii 20% aqueous showed maximum activity. Total phenolic content (TPC) 80%methanol exhibited high value in O. basilicum and S. asoca and aqueous 0% has a high TPC content in M. koenigii. The study of medicinal plants is an important area of research in modern medical science for better results and benefits to society and human safety. Use of me...

Sabi Ur Rehman1*, Laiba Arshad1, Saman Ali1, Shazma Massey2, Safeer Khan3, Abdul Samad4 and Fazal-Ur-Rehman5

...bacterial and antifungal activity assessments revealed moderate efficacy against Candida albicans, Staphylococcus aureus and Escherichia coli, comparable to Amoxicillin and Fluconazole. Further discussion explores the antibacterial effects of Ag NPs, highlighting their potential applications in combating bacterial infections. These findings underscore the significance of green synthesis methods in nanoparticle production and their potential roles in various fi...

Sara H. Zughayyar*, Amer H. Gyad 

...xamine the antidiarrheal activity of the alcoholic fruit extract of Prosopis farcta L. in a rat model. Thirty male Albion Wistar rats randomized into six equal groups of five as follows: negative control (received distilled water), positive control (induced diarrhea with 2 ml castor oil), and experimental groups that received 2 ml castor oil followed by oral administration of different doses of Prosopis farcta L. fruit ethanolic extract (300 mg/kg, 400 mg/kg,...

Ying Chen1, Chao-Zheng Li2, Zhun Yu3, Jia Zhou4, Yan Xu4, Zhe Lin4, He Lin4* and Xiao-Wei Huang4*

...rdial tissue, reduce the activity of MDA in myocardial tissue, reduce interstitial edema and inflammatory infiltration, and improve the structural damage of rat myocardial tissue. The expression levels of HO-1, NQO1 and Nrf2 protein in rat myocardial tissue were up-regulated. In conclusion, VAP can improve the structural damage of rat myocardial tissue, improve the antioxidant activity of myocardial, and reduce oxidative str...

Khansa Jamil1, Muhammad Ramzan Khan1, Asad Jan2 and Ghulam Muhammad Ali1

...xamine its antibacterial activity and phytochemical screening. Antibacterial assay was carried out by well diffusion method. A maximum number of compounds were eluted by methanolic extract by thin-layer chromatography and a total of 70 compounds were identified by GC-MS analysis. The phytochemical screening showed that the methanolic extract of the whole plant was rich in alkaloids and tannins. Zones of inhibition around the bacterial colonies show the antibac...

Nusirat Aderinsola Sadiku1, Oluwatoyin Adenike Fabiyi2* and Tesleem Taye  Bello

Muhammad Ali Raza1*, Aneela Zameer Durrani2, Muhammad Muddassir Ali3, Tariq Usman4, Bilques Bano5, Nazia Rubab6, Syed Tasadak Mehdi7, Muhammad Wasim Iqbal8, Kumayl Hassan Akhtar9, Hira Hameed10

...the in vivo anthelmintic activity of seeds of Azadirachta indica and other synthetic drugs comparatively compare and to justify the said seed consumption as an anthelmintic by the customary therapists of animals in South-Asia. Crude aqueous extract (CAE) from seeds of A. indica at the dosage of 2 g/kg of body weight,  levamisole HCL at the dose rate of 7.5 mg/kg and 3.0% oxyclozanide BP (vet), 1.5 levamisole hydrochloride BP (vet) and 0.382% cobalt sulpha...

Wei Wan1, Xiao-Li Wang1, Shu-Juan Wang2, Qin Si2 and Li-Qing Duan1*

...e highest GST inhibition activity, followed by cuminaldehyde. Pearson correlation analysis revealed a significant negative correlation between GST inhibition rate and number of antagonistic binary mixtures. In conclusion, our findings suggest that 2-ethylimidazole and cuminyl alcohol have high toxicity against P. sinica. L-carvone was the best synergist, and binary mixtures of l-carvone with dihydrocarvone, cuminaldehyde, cuminyl alcohol, d-carvone, and estrag...

Dan Song1,2, Ming-Juan Ge3, Jie Li1,2, Yi Jiang1, Xiu-Mei Kong1, Jiao-Jiao Xu1, Xu Ji1,2, Rui-Xin Shi1 and Qin Zhao1,2*

...londialdehyde (MDA), and activity of total antioxidant capacity (T-AOC), catalase (CAT) in mice liver were measured; while SOD and MDA contents and activity of T-AOC, CAT, Na+-K+-ATPase, Ca2+-Mg2+-ATPase, pyruvate kinase (PK) and phosphofructokinase (PFK) in mice brain were evaluated. In the results, G. straminea ethanol extract markedly enhanced hypoxia tolerance in mice. It attenuated hypoxia-induced oxidative stress by re...

Aleena Kokab1, Ali Ahmad Sheikh1*, Masood Rabbani1, Wasim Shehzad2, Muhammad Ilyas Riaz1, Sohail Raza1 and Rida Haroon Durrani1

...culture, phage virulence activity was rapid and high at a high (100) multiplicity of infection with phage SEPL01 depicting the best activity among all. Compared to the solophage suspensions at high MOI, the phage cocktail comprising all three phages did not let the bacteria regrow until 24 h overcoming bacterial resistance. All the three bacteriophages demonstrated a broad host range within the genus Salmonella (Enteritidis,...
Yi Zhao1,2,3, Lei Luo1,2, Liqi Tan4, Jianhua Huang1,2, Dongliang Liu1,2,5, Shigui Jiang1,2 and Lishi Yang1,2*
...ure, the pyruvate kinase activity in the hepatopancreas and gill tissues of crayfish was gradually increased, and the fatty acid synthase activity at 10°C and 30°C were significantly lower than the control group of 25°C. Furthermore, lysozyme, catalase and superoxide dismutase in 10 °C and 30 °C were significantly lower than that of 25 °C. ELISA revealed that HSP90 activities was enhanced with the inc...
Rabiea Pervaiz, Shaista Bano*, Sarfraz Ali Tunio, Abdul Nabi Jatt and Aisha Amber Soomro
...ing strong antibacterial activity was obtained by screening/selection method and designated as B. pseudomycoides strain SB138m. The sequence of 16S rRNA gene of both wild type and mutant strains of B. pseudomycoides was comparable. In vitro test for antagonism of B. pseudomycoides strain SB138m against indicator cells showed that the strain contained antibacterial potential. The present study shows inhibitory spectrum of B. pseudomycoides SB13m with conclusion...

M. Azalou1,3*, C. C. Kpomasse1, A. S. Assani3,4, I. T. Alkoiret3,4, Wéré Pitala1,2  

...goose farmers whose main activity was trade (56.1%); group 2 was composed of secondary level herders whose main activity was agriculture (59.38%); and group 3 included public servants (27.59%) with university-level education. As for the feeding of the geese, Group 3 fed more feed than Groups 1 and 2, where the majority of farmers used cereals, agro-industrial by-products, and food waste (p<0.05). The farming method and th...

Rana Mahmood Ahmad*, Orooba Mohammed Maeed  Ibrahim

...y. The anti-inflammatory activity of clove oil extracts and their efficacy in decreasing inflammation in chronic inflammatory models were evaluated using the cotton pellet-induced granuloma method. Decreasing granuloma weight suggests that the proliferative phase has been successfully suppressed. In the current study, treatment with clove oil extract on infected rats significantly decreased levels of the pro-inflammatory cytokine TNF-α value after nine d...

Turrini Yudiarti*, Sugiharto Sugiharto, Endang Widiastuti, Hanny Indrat Wahyuni, Tri Agus Sartono, Maulana Hamonangan Nasution

...operties and antioxidant activity.The obyective of this study was to see how adding the fermented product of the fungus Monascus purpureus as a feed additive affected to physiological parameters, intestine microbial population, and broiler internal organ weight. The method was one hundred and fifty un-sexed one-day-old chicks (DOC) were reared in an open cage. With three treatments, the study used a completely randomized design. The treatments consisted of a d...

Madbouly*, H.M.; Saif**, M.A. and Hussein* , A.S.

...ys of age for phagocytic activity of macrophages. All groups were challenged with vvNDV for detecting the protection percent. From this study it could be concluded that MDV vaccine has an immunosuppressive effect on chicks and this could be antagonized by immunostimulant as curcuma longa The surprising immuno-stimulatory effect of curcuma is in the induction of protection level 80% in treated but not NDV vaccinated group which equivalent to that group vaccinat...

Rabia Anjum

...ich results in decreased activity of brain such as thinking and increased dependence on others to fulfill the daily tasks. The pathological identification of AD is beta amyloid accumulation or development of neurofibrillary tangles of tau proteins. Currently different hypothesis was proposed in the progression of disease which are amyloid cascade, tau and cholinergic hypothesis. Other than that age, family history, injury, high blood pressure and genetic may p...

El-Sabagh, I.M.; Hussein, H.A.; Amer, H.M.; El-Sanousi, A.A.; Reda,I.M. and M.A. Shalaby

... protein revealed high reactivity with hyperimmune antiserum to BRV when tested by immunoflurescence assay. Using solid phase ELISA, the VP7 expressed protein was detected intracellulary and extracellulary at 48 and 96 hours post-inoculation using polyclonal antibodies against BRV, respectively. The VP7 expressed protein was not detected in Coomassie blue stained SDSPAGE but produced a detectable band in Western blot assay. The reactiv...

Amer, H.M.; Hussein, H. A.; El-Sabagh, I. M.; El-Sanousi, A. A. Saber,M.S. and Shalaby, M. A.

...icated by its distinct reactivity in immunofluoresence, solid phase ELISA and Western blot.

...
El-Dougdoug, Kh.A. t , S.A. Ghaza12 , A.A. Mousa2, H. Fahmyj and A.R. sofy2 
... peroxidase isozymes and activity, total RNA content and reserves transcriptionpolymerase chain reaction (RT-PCR). The severe isolate (ARC) gave the highest OD. value (2.204) in ELISA, followed by the mild isolate (TB) (1.958) and the last latent isolate (N) (1.669). These isolates differed also in incubation period, intensity of symptoms and response to sensitivity of woody indicator plants and differential hosts. The CPsV-EG isolates showed differences in is...

M.A. Abo-EInasr l, Kh.A. EL-Dougdougl, M.H. El-Kattan2 and L.A. Salem2

... related to inducers and activity of peroxidase and chitinase enzymes. Salicylic acid (0.5%) and potassium sulfate (3%) gave the highest effect in inducing SAR. where the treatment with them had forbid disease symptoms, and virus concentration was (0), 25 days post inoculation. In addition, the biochemical changes reached to the maximum values. whereas other chemicals gave a medium ability to induce SAR and gave varied values.

...

M.E. Shawky and A.M. Daoud.

...ith 3' to 5' exonuclease activity (PFU and Vent) was used in the amplification of large fragments (2 Kb, 3 CD genes) of foot and mouth disease virus (FMDV). Such long-distance polymerase chain reaction (LD-PCR) was conducted to reduce mismatch extension rates and improve epidemiological cloning and sequencing Studies. When enzyme mixtures in the reaction were optimized. The best results were obtained with Tth and PFU polymerases at concentrations of 2.50-0.40,...

Estabraq Hayder Khayoon, Ammar Ahmed Abdulwahid*  

...and decreased locomotors activity in the Y maze test. Curcumin’s anti-apoptotic, anti-inflammatory, and antioxidant properties have not been thoroughly examined in neurotoxicity given on by Acrylamide, nevertheless. We investigated whether Curcumin may protect against oxidative stress, apoptosis, and inflammation in neurons brought on by Acrylamide exposure. In conclusion acrylamide alters the neurobehaviors and oxidatively stressed animals .However Cur...

Ahmed M. Manthoor, Ali H. Saliem* 

...hanism of action and the activity of Portuluca oleracea methanolic extract in vitro against Escherichia coli. The first step was involved collection and extraction of P. oleracea with absolute methanol in a Soxhlet apparatus and phytochemical analysis of extract. While in the second step, the antibacterial effects of the extract as compared with ciprofloxacin, as well as zone of inhibition, minimum inhibitory concentration (MIC) and the minimum bactericidal co...

Tabinda Nowsheen1, Sayed Wadood Ali Shah2, Ali Hazrat1*, Muhammad Yahya1, Gul Rahim1, Muhammad Mukhtiar4 and Muhammad Ajmal Khan3

...is nearly similar to the activity of ciprofloxacin (standard). The methanolic leaves extract of A. maritime displayed the highest scavenging activity (78.09µg/ml) in DPPH, while stem methanolic extract showed 61.81 µg/ml activities. In ABTS the highest activity (84.13µg/ml) was observed on leaves extract and lowest (69.18µg/ml) on stem extract. Our current study rev...
Nael Abutaha, Fahd A. AL-Mekhlafi*, Khalid Elfaki Ibrahim, 
Mohammed S. Al-Khalifa and Mohamed A. Wadaan
...t showed good larvicidal activity, with an LC50 = 33.9 μg mL−1 and LC90 = 64.1 µg/mL at 24 h post exposure. The midgut sections of treated larvae showed morphological alterations such as microvilli damage, loss of nuclei, and peritrophic membrane degeneration. The extract also showed high cytotoxic activity against HUV-EC cells, with an LC50 of 19.8 µg/mL. The results indicated that G. mang...

Riskayanti Riskayanti1, Hikmah Hikmah2*, Muhammad Irfan Said2, Nahariah Nahariah2 

...ry fiber and antioxidant activity. The lack of vegetables is one of the weaknesses of nugget products. Therefore, diversification of processed chicken nugget products with the addition of vegetables is needed. This research aimed to analyze the effect of cooking treatment and vegetable addition level on antioxidant activity, dietary fiber, pH and cooking loss of chicken nuggets. The research design consisted of two factors...

Siqiang Li1,2, Tiantian Wang1, Peng Sun1, Airong Gao1, Xin Gong1, Yuanhong Xu2, Baogen Wang2, Jun Wu1* and Bo Liu1*

...ngerprint. The enzymatic activity and optimal reaction conditions of MDS I were detected using DNA sequencer-assisted fluorophore-assisted carbohydrate electrophoresis. We obtained MDS I with a purity exceeding 90% in gram scales, which was capable of digesting α-1,2 linked mannose residues in high selectivity. The highest enzymatic activity of MDS I occurred at a pH of 7.0 and a temperature of 42°C. Enzymatic

Limbang Kustiawan Nuswantara, Eko Pangestu, Marry Christiyanto, Santoso Dwi Pratomo, Elyza Zahrotul Muhtaromah

...e nutrients, Antioxidant activity
...

Khaeruddin1, Gatot Ciptadi2, Muhammad Yusuf3, Iswati4, Setya Budhi Udrayana4, Sri Wahjuningsih2*

... added and mitochondrial activity was enhanced under the same condition. The concentration of malondialdehyde (MDA) was lower (P=0.05) with the addition of 3 mM BHT at 24 hours of storage. In conclusion, the addition of 3 mM BHT showed promising potential to maintain chicken sperm quality after liquid storage.
 
Keywords | Butylated hydroxytoluene, Gaga chicken, Diluent, Liquid storage, Semen, Sperm
...

Eman Said El-Hadad*, Hesham Ahmed Madian, Mahmoud A.E. Hassan, Mohamed Fahmy Saad, Abdelghany M. El-Shhat, Entesar Zakaria Eliraqy

...al antioxidant capacity, activity of SOD and catalase, and IgG and IgM increased, while malondialdehyde and cortisol decreased in G2 and G3 compared with G1. In conclusion, dietary supplementation of L-arginine (0.4 g/kg) for three months improved hematology, protein metabolism, lipid profile, liver, kidney, and intestine functions, antioxidant status, immunity and welfare of Egyptian geese under heat stress condition.
 
Keywords |...

Pramudya Andiana*, Moch. Geerhan Miraja Syahdan, Khothibul Umam Al Awwaly, Abdul Manab

...l characteristics and bioactivity of the hydrolysate. A laboratory experimental method using a completely randomized design (CRD) was used in this research. In this study, chicken head protein was hydrolyzed using different combinations of bromelain (b) and papain (p), namely CHP (without hydrolysis); CHP1 (0.25% b and 0.75% p); CHP2 (0.5% b and 0.5% p); and CHP3 (0.75% b and 0.25% p). The data were analyzed using one-way analysis of variance followed by Dunca...

Muhammad Akram1, Anirban Mandal2*, Mehwish Iqbal3, Arindam Mukherjee4, Ritika Bandyopadhyay5, Surendar Rangasamy6, Rida Zainab1, Muhammad Talha Khalil1, Pragnesh Parmar7 and Umme Laila1

...stituents with antiviral activity exists in numerous plants, for instance, rutin, a flavonoid glycoside generally found in a range of botanicals, is efficient against herpes simplex virus type 1 (HSV-1), herpes simplex virus type 2 (HSV-2), and influenza A virus. Ascorbic acid, beta carotene and lots of phenolics play active parts in decreasing inflammation, postponing aging, and averting certain kinds of carcinomas. There are some phenolic compounds such as t...

Peixia Yu1*, Lijun Bo2 and Xueyin Song1

...peroxide dismutase (SOD) activity, creatine phosphokinase MB (CK-MB) and cardiac troponin-I (cTnI). The total apoptotic cardiomyocytes, B cell lymphoma 2 (Bcl-2) and Bax protein and mRNA expression were detected in the myocardial ischemia (MI) region. The HR and the MAP of the Fen group exceeded that of the I/R group, while the LVDP and ±dp/dtmax were approximate to the basic values. The MDA concentrations and CK-MB values of the Fen group went down and...

Aalaa S. Saad1*, Amira A. Elokle2, Dalia Y. Youssef2, Neven M. Omara2, Samr Kassem3

...aluate the antibacterial activity of synthesized Chitosan nanoparticles (CS-NPs) and CS-LZ-NPs against E. coli O157 in chilled chicken fillets and relative eaeA (Intimin), stx2 (Shiga toxin) expression. The average particle size was 250 nm and 281.4 nm for CS-NPs and CS-LZ- NPs and the PDI (polydispersity index) was 0.09 and 0.58, respectively. TEM imaging showed uniformity and ranging in size from 13.1 to 17.6 nm and 15.6 to 19.5 nm for CS-NPs and CS-LZ-NPs, ...

Sara Brikat, Mouloud Lamtai*, Miloud Chakit, Laila Ibouzine-Dine, Ilhame Fitah, Oumaima Abouyaala, Abdelhalem Mesfioui, Aboubaker El Hessni

... oxide (NO) and catalase activity (CAT) in the hippocampus. The administration of Curc and/or Los increased significantly the recognition index (p < 0.01) as compared with the HFD group, and were able to prevent this effect on the memory induced by the HFD (p < 0.01). Additionally, the levels of TBARS and NO in HFD group significantly exceeded the respective values in female animals when compared to control rats (p < 0.05). In contrast, the administra...

Shamsa Jabeen and Javed Iqbal Qazi*

...ost-transplantations. CK activity of control and EDL muscle grafted mice with probiotics showed 157% and 130% increase, respectively on day 5, whereas on 14th days post-transplantation CK values showed 45.6% and 4%, respectively increase compared with the values of intact control. The LDH activity increase 52.27% and 19.46%, respectively on day 7 when compared with intact control. On 14th days post-transplantation correspond...

Shanti Fitriani*, Usman Pato, Yusmarini Yusuf, Emma Riftyan, Evy Rossi

...Keywords | Antimicrobial activity, bacteriocin, Pediococcus pentosaceus, natural biopreservative, fishballs, cold temperature
...

MUHAMMAD ASLAM1*, ZAHRA NOREEN2, AMINA ASGHAR1, ABRAR HUSSAIN2, RASHAD MEHMOOD3, MUHAMMAD USMAN KHAN4, KAYNAT SALEEM5, MUHAMMAD TAHIR HUSSAIN6* & ASMA CHAUDHARY7

... of theory. The global reactivity parameters were explored using the energy of frontier molecular orbitals. Natural bond orbital analysis has been carried out at B3LYP/6-311+G(d,p) level of theory to discover hyper conjugative interaction and stability of the title molecule. Moreover, the product showed the reverse urease inhibition activity.

...

SYED MUJTABA HAIDER1, KHIZAR HAYAT BHATTI1*, EJAZ HUSSAIN SIDDIQI1, SYED MAZHAR IRFAN1,`2, & ALLAH BAKHSH GULSHAN2

... assess of antibacterial activity of ethanolic, methanolic and aqueous extracts of Aloe vera L. against six bacterial strains (Staphylococcus aureus; Streptococcus pyogenes; Shigella sonnei; Escherichia coli (1) (4C11); Escherichia coli (2) (ATCC 13048) and Neisseria gonorrhoeae). Agar well diffusion method was applied to assess the antibacterial activity of these extracts. Their antibacterial activities were associated with...

MAHRUKH SHAHID1, KHAJISTA JABEEN1* & SUMERA IQBAL1

...heir in vitro antifungal activity along with a reference fungicide (Mancozeb). Data obtained after 7 days of incubation depicts that maximum antifungal activity was observed in fungicide with 89% inhibition in the radial diameter of the test fungus. n-hexane and chloroform also effectively retarded the growth of F. oxysporum, whereas n-butanol and ethyl acetate fractions gave minimum activity<...

MADIHA AFTAB1, ARIFA TAHIR*1, TAYYABA ASIM1 & IRFANA MARYAM2

...owed that maximum enzyme activity (297±0.1 U/ml/min) was obtained by using AFM02 medium containing g/L: sawdust, 5.0; glucose, 5.0; peptone, 6.0; MgSO4.7H2O, 0.25; KCl, 0.5; KH2PO4, 0.025. Optimized conditions for maximum enzyme yield were inoculum size 2.5%, Temperature 25ËšC, pH 4.5, incubation period 7 days and moisture content 60%. Eleven different inducers were evaluated but FeSO4.7H2O showed maximum enzyme production (2156±0.57 U/mL/min). B...

MUHAMMAD MANSHA1, MAIRA HAFEEZ1, QAMAR ALI1, ABRAR HUSSAIN1, MUHAMMAD TARIQ1 & ATIF YAQUB2

...tro for their biological activity against microorganisms by employing agar well diffusion method. The microbes, Escherichia coli, Staphylococcus aureus and Candida albicans were cultured on agar plates. Wells in agar plates were loaded with 50 μl of 0.02 μg/ml and 0.04 μg/ml of hydrazone derivatives. Biological activity was examined by measuring the zone of growth inhibition. Compounds, 5, 6 and 11 exhibited none or...

ASIFA BASHIR1, AAMIR MUSHTAQ2* & TOOBA MEHBOOB3

... Free radical scavenging activity by plant extract was observed as 68±0.33 % as compared to rutin (58±1.15 %) at concentration 2.56 mg/ml. Similarly, in vivo studies indicated that Phyllanthus emblica 80 mg/kg significantly reduced the glucose level in diabetic rats up to 166 ± 0.7 mg/dl on day 8th at 8th h as compared to diabetic rats 380 ± 0.7 mg/dl. Similarly, it also reduced the weight in rats up to 274.11 ± 0.97 g as com...

SEHRISH MUSHTAQ1, MUHAMMAD SHAFIQ1, MUHAMMAD ASHFAQ*1 FAIZA KHAN1, SOHAIB AFZAAL1, UMMAD HUSSAIN1, MUBASSHIR HUSSAIN1, RASHID MUKHTAR BALAL2 & MUHAMMAD SALEEM HAIDER1

... screened for antifungal activity against Alternaria solani which causes losses to crops. A total of twelve strains were identified based on morphological and biochemical tests following Bergey’s manual of systematic bacteriology. The antagonistic potential of bacterial endophytes to A. solani was explored using the agar absorption method. This study showed the antifungal potential of Pantoea sp. (35.66%), Ensifer adhaerens (35.33%), Citrobacter diversus...

ABRAR HUSSAIN1, AQSA KHALIL1, SAIRA ZAHEER1, MUHAMMAD LATEEF2 & MUHAMMAD MANSHA1

...termine the anthelmintic activity of Tribulus terrestris L. and Ziziphus mauritiana Lam. Whole plant of Tribulus terrestris L. and leaves of Ziziphus mauritiana Lam. were used. The plant materials were dried, ground firmly, macerated in ethanol and then the crude ethanolic extract (CEE) was prepared. Adult motility assay (AMA) was carried out on adult Haemonchus contortus to analyze the anthelmintic efficacy of CEE of the whole plant and the leaves of Tribulus...

ASMA ZAFAR*, MONIBA KHAWAR, MAHNOOR CHAUDHRY, SAYYEDA SANA BATOOL, AMJAD HUSSAIN** & MUSHTAQ AHMAD SALEEM

...nd Cadherin enhances the activity of azurin by inducing apoptosis in cancerous cells, disrupting signaling among cancerous cells and inhibiting the growth of cancerous cells as well as suppressing the activity of tumor cells. This review article focuses on the activity of the bacterial protein azurin as an anti-cancer agent and also the properties of azurin which makes it one of the prefer...

Uqba Mehmood

...wed very low proteolytic activity in comparison with proteolytic activity of normal spores of wild type Bacillus subtilis PY79. It appears that defective spores lack enzymes with proteolytic activity which is necessary for germination. Since all protease deficient mutants are asporogenous. Although some mutants, producing very low levels of protease are still able to sporulate, with some d...

MUHAMMAD NADEEM1, MUHAMMAD WASEEM MUMTAZ1&MUHAMMAD DANISH1

...stigation of antioxidant activity and α-amylase inhibition potential of hydroethanolic leaf extracts of Vitexnegundo. Freeze drying assisted ultrasonicated extraction revealed highest level of total phenolic contents (258.29±2.52 mgGAE/g DE) and total flavonoid content (155.91±1.75 mgRE/g DE) in 60% hydro-ethanolic V. negundo leaf extract. Furthermore, total antioxidant power (254.35±1.56 mg AAE/g DE) and antidiabetic effectbased on ...

MUHAMMAD MANSHA*1, QAMAR ALI1, UROOJ FATIMA DILAWARI1, ABRAR HUSSAIN1 & MUHAMMAD TARIQ1

...alogue 9 showed moderate activity against E. coli. Similarly, compounds, 1, 2, 3, 6, 7, 8 and 9 were found to be inactive or insignificant against S. aureus. Analogues 4 and 5 displayed moderate bioactivity against S. aureus. Similarly analogues 1, 2, 4, 7, 8 and 9 were found to be inactive or insignificant against C. albicans. Compound 3, 5, and 6 were found more effective against C. albicans. Among aurones 2, 3, and 4 show...

María Julia Traversa1*, Mónica Saracco2, María Alejandra Colombatti Olivieri3, Fernando Paolicchi4, Edgardo Rodriguez5, Silvia Estein5, María Cristina Jorge5, William C. Davis6

...roduction, and metabolic activity assessed peripheral blood mononuclear cells (PBMC) stimulation. The study enrolled 19 Argentinian Holstein cows older than two years classified into four groups, one of PPDb reactors that transited the EPP period (PPDbEPPp) (n=5), another of PPDb reactors that did not transit the EPP period (PPDbNoEPPp) (n=5), the third of no PPDb reactors that transited the EPP period (NoPPDbEPPp) (n=5), and the last of no PPDb reactors that ...

Deni Novia*, Indri Juliyarsi, Rizki Dwi Setiawan, Clara Mustika, Cindi Melani

...aluated were antioxidant activity, energy value, moisture, protein, fat, ash content, solubility, color (L*, a*, b*), and sensory evaluation of hedonic preferences and qualities. The results revealed that different drying times showed significant differences (P<0.05) in antioxidant activity, energy value, protein, fat, ash, moisture content, color (L*, a*, b*), and sensory properties, except for color attributes in the he...

Jacob Situmeang1, Lovita Adriani1*, Deny Saefulhadjar1, Safri Ishmayana2

...otease and lipase enzyme activity, which can increase digestive tract enzymes in laying hens. In this study, it is hoped that probiotics can increase protein levels and reduce lipid and cholesterol levels in chicken egg yolks. This study aims to determine the activity of the protease and lipase enzymes from yogurt and the effect and level of use of probiotic powder, which can increase protein and reduce lipid and cholesterol...
Aliya Irshad Sani1, Shumaila Usman2*, Zile Rubab1, Sufyan Ahmed3, Sana Iqbal3 and Zehra Ahmed4
...to accentuate anti-tumor activity. The results of OX40 and OX40L in cancer immunotherapy are still limited and most of the studies have evaluated their expression in tumor biopsies. In this study we aimed to find out gene expression of costimulatory molecules in naïve oral squamous cell carcinoma patients in saliva and blood as noninvasive biological samples by qPCR. The results revealed significant difference between the cycle threshold (Ct) values in th...

Youfang Li1, Xu Li2, Shaik Althaf Hussain3, Jayasimha Rayalu Daddam4 and Zhigang Chen5*

...olved. The combinational activity was enhanced along with quercetin.

...

Laila Ibouzine-Dine1*, Inssaf Berkiks1,2, Mouloud Lamtai1*, Hasnaa Mallouk1, Ayoub Rezqaoui1, Abdeljabbar Nassiri1, Abdelhalem Mesfioui1, Aboubaker El Hessni1

...e aimed to determine the activity of NO during the early and late critical periods of structural and functional maturation of the central nervous system (CNS). In this study, we focused on the prefrontal cortex, hippocampus, striatum, and hypothalamus of male and female “Wistar” rat pups, as these areas have differential developing states. NO level was determined on postnatal days (PND) 1, 2, 3, 4, 7, 8, 9, 10, 11, 12, 14, 15, 16, and 17. The super...

Muhammad Yusuf1*, Abd Latief Toleng1, Sahiruddin1, Masturi1, Hasrin1, Musdalifa Mansur2, Hendrikus Fatem3, Johan Koibur4

...synchronization, Ovarian activity, Heasynch and Select synch
...

Tianhoun Denté Fidèle1,2*, Meda Nãg-Tiéro Roland2, Zabré Geneviève3, Koama Benjamin2, Kaboré Adama1, Tamboura H. Hamidou1, Bélem Adrien Marie Gaston4 

...e responsible for the bioactivity observed in both plant extracts. These results show that plant extracts have an effect on H. contortus and could serve as an alternative to synthetic anthelmintics. However, in vivo anthelmintic and toxicity tests should be considered in order to confirm their use by the farming community. 

...

Abeer Alahmari1,2*

... the in vivo antioxidant activity of aqueous myrrh extract (AME) on oxidative stress-dependent nephrotoxicity caused by ethanol in rats. Male Sprague‒Dawley rats orally received 40% ethanol (3 g kg-1) and were then orally treated with (500 mg kg-1) AME daily for 30 days. Kidney function, oxidant and antioxidant status, and histopathology alterations in renal tissue were measured. Animals that received ethanol displayed nephrotoxicity, as confirmed by marke...

Kanwal Razzaq1*, Mudssar Aslam1, Sana Arif2, Ansa Idrees3 and Fatima Mubashir3

...fingerlings. The minimal activity retained by trace elements was observed in diets containing lactic acid. The results presented that best responses showed lactic acid in comparison of other dietary supplemented organic acids.

...

Qurrat ul Ain Shafique1, Sana Batool2, Hanfa Ashfaq2, Asima Tayyab2, Roquyya Gul3 and Mahjabeen Saleem1*

... Thus, refolded IL-2 had activity identical to that of authentic IL-2 and enhanced the anti-tumor activity of HepG-2 as compared to MCF-7 cells. These conclusions suggest the potential use of the refolded cytokine as immunotherapeutic agent for treatment of hepatocellular carcinoma.

...

Marah Salim Hameed1, Ali Ibrahim Ali Al-Ezzy2*

...ive and immunomodulatory activity of vitamins C and E -sodium selenite in mice intoxicated with sodium nitrate. Thirty healthy adult male mice of 25-30gm body weight divided randomly into six groups (5 mice/each) administered the following daily for 2 weeks, respectively: Vitamin E -sodium selenite 0.5 ml/LDW(T1); vitamin C (0.5 gm/L (T2); NaNO3 0.5gm/L (T3); NaNO3 (70 mg/kg) and vitamin E -sodium selenite 0.5 ml/L (T4); NaNO3 [70 mg/kg and vitamin C 0.5gm/ L]...

Saadatin Nurul Jannah1, Edhy Sudjarwo1, Osfar Sjofjan2*

...mpounds, and antioxidant activity as a substitute for synthetic antibiotic feed additives given to broiler chickens. This study was conducted using a laboratory experiment using garlic peel powder as a material, an active substance content test using a quantitative flavonoid test, and antioxidant activity. Additionally, onion peels are used as a feed additive for broiler chickens to evaluate production performance and blood ...

Noor-ul-Ain1, Zulfiqar Ali1*, Saba Naz1, Kiran Saleem1,2, Syeda Rida Hasan1, Sana Arif1, Rida Ahmad1,3, Nida Naeem1, Zarmina Zainab1 and Aliza Batool1,3

...r’s pre-enrichment activity budget data was collected by scan sampling method of 70 h, documenting the cage area and behavioural ethogram. The observed behaviours were resting, eating, drinking, locomotion, aggression, urination, defecation, fighting, pacing, playing, foaming, cage exploration, and being out of view. Two different enrichments were installed for two pairs. The first pair was provided with a feeding enrichment consisting of a large wood lo...

Noura K. Al-Suwailem1, Nancy N. Kamel2, Ahmed O. Abbas1,3*, Farid S. Nassar1,3 , Dalia A.A. Elsayed4, Gouda F. Gouda1,5, Hosam M. Safaa3,6

...d endogenous antioxidant activity. Meanwhile, plasma total protein, cholesterol, triglycerides, creatinine, urea levels, and liver enzymes activity were significantly (P<0.05) increased. The carcass yield and meat quality showed significant (P<0.05) deterioration in response to heat exposure. MLM administration to the basal diet significantly enhanced blood metabolite levels, hematological parameters, antioxidant activ...
Julio Adolfo Corzo-Bacallao1*, Carlos Alfredo Salas-Macías1, Osvaldo Fonseca-Rodríguez2,3, Felipe R. Garcés-Fiallos1, Erika Isabel Alcívar-Muñoz1 and Henry Fabricio Baque-Loor1 
 
...he higher photosynthetic activity associated with the higher intensity of incident solar radiation, although the relationship is not linear. In our results, flowering and fruiting were not affected by the level of shade, nor were their precursors, such as nodes per productive branch and productive nodes per productive branch. On the other hand, coffee plants at full sun exposure in S1, without shade, decreased chlorophyll measured in SPAD units, as a possible ...

Shah Zeb Khan1, Ali Hazrat1*, Farman Ali Khan2, Muhammad Yahya1, Gul Rahim1, Muhammad Mukhtiar3, Muhammad Ajmal Khan4 and Hayat Ullah1

...ects. Strong antioxidant activity was found for BR (IC50= 62.5 µg/mL) and BS (IC50= 80 µg/mL) probably due to the presence of flavonoids in butanol fractions, evident from the Fourier Transform (FT-IR) spectral analysis which gave distinct absorption of flavonoids functionalities. In antimicrobial studies, CR exhibited strongest antibacterial activity against E. coli, S. flexneri and S. aureus with inhibition zon...

Sarhad Journal of Agriculture

March

Sarhad Journal of Agriculture, Vol.40, Iss. 1, Pages 01-262

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