Toxicological Effects of Heavy Metal (Pb+2) on Peroxidase Activity in Freshwater Fish, Catla catla
Toxicological Effects of Heavy Metal (Pb+2) on Peroxidase Activity in Freshwater Fish, Catla catla
Nosheen1, Sajid Abdullah1, Huma Naz2* and Khalid Abbas1
ABSTRACT
Freshwater ecosystems have been contaminated with a wide range of pollutants. Heavy metals are important contaminants of aquatic system and can cause oxidative stress in fish. Evaluation of antioxidant in fish can reveal metal toxicity in the water ecosystem. Therefore, this experiment was planned to assess the acute affect of lead (Pb+2) on peroxidase (POD) activity in tissues viz. liver, gills, kidney, muscle, heart and brain of fish Catla catla exposed for 4-day. After each sampling (24-hr interval) fish were dissected and required organs were obtained. Results showed that the POD activity was augmented in all selected organs of Pb+2 exposed fish in relation to control. The POD activity in organs of fish followed the order: brain>liver>gills>kidney>heart>muscle. Regression analysis showed a positive relationship between POD activity and duration of exposure. It was also concluded that antioxidants enzymes can be used as a valuable biomarker of oxidative stress in aquatic animals.
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