Both Quorum Sensing (Qs)-I and Ii Systems Regulate Escherichia coli Flagellin Expression
Both Quorum Sensing (Qs)-I and Ii Systems Regulate Escherichia coli Flagellin Expression
Yang Yang1,2, Yun Liu1, Mingxu Zhou1 and Guoqiang Zhu1,*
ABSTRACT
For elucidating effect of quorum sensing (QS) systems I and II (QS-1 and QS-II) on Escherichia coli flagellin expression, E. coli F18ab strain 107/86 was modified to either express acyl-homoserine lactone (AHL) synthase (QS-I) or deleted for autoinducer 2 (AI-2) expression (QS-II). AHL expression and deletion of luxS (AI-2) both inhibited flagellin expression, as measured by motility assays, bacterial gene expression, and host responses to infection. The QS systems and flagellin were coordinately regulated, as deleting fliC caused decreased QS-II activity.
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October 2018
Vol. 50, Iss. 5, Pages 1601-1998
