An Antimicrobial Cerebroside from the Liposoluble Constituent of Cervus Nippon Antler Velvet Layer
An Antimicrobial Cerebroside from the Liposoluble Constituent of Cervus Nippon Antler Velvet Layer
Nina Bao1,*, Yongguang Yin2 and Panpan Wang3
ABSTRACT
Using petroleum ether to extract an antimicrobial cerebroside from the liposoluble constituent of cervus nippon antler velvet layer was studied in this paper. Single-factor experiment was used to research the effect of liquid-to-solid ratio, standing time and centrifugation time on the extraction of crude cerebroside. The optimal extraction conditions for the cerebroside as follows: liquid-to-solid ratio 15, standing time 45 min, and centrifugation time 6 min. The extracted cerebroside was purified and identified by using silica gel column and TLC, respectively. IR analysis showed that the extraction has hydroxyl and amide groups, which was proved to be cerebroside. Meanwhile, bioactivity showed that the extraction has antibacterial activity, and the purified one is better than the crude one.
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October 2018
Vol. 50, Iss. 5, Pages 1601-1998
