Evaluation of Phytochemicals, Antioxidant, and Antibacterial Potential of Artemisia maritima Various Parts from Lower Dir Pakistan
Evaluation of Phytochemicals, Antioxidant, and Antibacterial Potential of Artemisia maritima Various Parts from Lower Dir Pakistan
Tabinda Nowsheen1, Sayed Wadood Ali Shah2, Ali Hazrat1*, Muhammad Yahya1, Gul Rahim1, Muhammad Mukhtiar4 and Muhammad Ajmal Khan3
ABSTRACT
The use of herbs for medicinal purposes has trace back to ancient times. The current study was conducted with aim, to assess the phytochemicals, antibacterial and antioxidant potential of the methanolic crude extract of leaves, stem, and roots of Artemisia maritime. The phytochemical screening of A. maritime leaves, stem and roots extract indicates the existence of flavonoids, terpenoids, saponins, tannins, phenolics steroids and carbohydrates but deficient of proteins. In minimum inhibitory concentration assay, the crude methanolic extracts showed significant inhibition against all tested bacterial strains at25, 50 and 100 µg/ml. The methanolic crude extract of A. maritime various parts showed MIC of 37.5µg/ml for S. aureus which is gram-positive bacteria followed by 75µg/ml for P. aeruginosa, (gram negative), and B. subtilis (gram positive) that is nearly similar to the activity of ciprofloxacin (standard). The methanolic leaves extract of A. maritime displayed the highest scavenging activity (78.09µg/ml) in DPPH, while stem methanolic extract showed 61.81 µg/ml activities. In ABTS the highest activity (84.13µg/ml) was observed on leaves extract and lowest (69.18µg/ml) on stem extract. Our current study revealed that A. maritime root exhibited significant antioxidant potential and good antibacterial effect which suggested its usage for treatment and management of different contagious diseases. In the present study we concluded that A. maritima possess therapeutic effectiveness.
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