Biological and Phytochemical Investigation of Heliotropium eichwaldii L.
Biological and Phytochemical Investigation of Heliotropium eichwaldii L.
Abdur Rauf1*, Farooq Jan1, Muhammad Qayash2, Zia-ul-Islam3, Rizwanullah1, Ikramullah Khan1, Muhammad Shuaib4, Muhammad Khalid5 and Samrin Gul6
ABSTRACT
In this investigation, we have analyzed the biological and phytochemical activities of Heliotropium eichwaldii. The crude ethanolic extract (25, 20, and 15mg/ml) was used against bacterial and fungal species. The four pathogenic bacteria (Micrococcus luteus, E. coli, Staphylococcus aureus, Bacillus subtilis) and two fungi (Aspergillus flavus and Aspergillus niger) were examined. The above-mentioned various ethanolic crude extracts of H. eichwaldii revealed the highest potential (15.82±0.40), (18.12±0.56), and (17.41±0.51) against S. aureus, a moderate activity (13.31±0.64), (15.43±0.52), (14.35±0.64), (11.34±0.50), (13.47±0.55), (14.21±0.67), (9.53±0.51), (15.32±0.53), and (2.15±0.65) against E. coli, B. subtalus, and M. leutues. A 15mg/ml crude extract of H. eichwaldii exhibited the lowest potential (2.15±0.65) against M. leutues, while a 20mg/ml extract showed a very high potential against A. niger and A. flavus. Furthermore, the antioxidant potential of the ethanolic extract revealed the maximum at 400mg/ml (76.03%) and 300mg/ml (70.01%). The phytochemical analysis revealed the presence of alkaloids, saponins, flavonoids, and phenols in the ethanolic crude extract.
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