Determining the Acute Toxicity of New Preparation Vetom 20.76 on Geese and Ducks
Determining the Acute Toxicity of New Preparation Vetom 20.76 on Geese and Ducks
Grigory Antonovich Nozdrin1*, Regina Gabdrahmanovna Utkina2, Anastasia Aleksandrovna Lelyak2 and Yana Viktorovna Novik1
ABSTRACT
The current study aim to investigate the acute toxicity of the new microbial preparation from a predatory fungus Arthrobotrys oligospora in birds. The experiments were performed on two-days-old goslings and ducklings which were divided into four experimental groups and a reference group. The fowls in experimental groups were supplemented with preparation once with dosages (2,000 µl/kg, 3,000 µl/kg, 4,000 µl/kg, and 5,000 ml/kg) while the fowl in the reference group were left untreated (they were given a placebo – distilled water). The experimental fowl were monitored every hour during the first day, and every day afterward for a total of 14 days. The live body weight was measured every week; the overall condition of the fowl, behavior, physical activity, water, and feed consumption were monitored. At the end of the experiment, autopsy and morphometry of internal organs were assessed. No toxic effect of the experimental sample (Vetom 20.76) was observed during the experiment. The fowl in the experimental groups had positive dynamics on the weight gain, growth, and development even at the dosage of the preparation of 5,000 µl/kg. During the general autopsy, no pathologic changes of internal organs were observed in the fowl in the experimental groups. At the end of the research, Vetom 20.76 was classified as a substance of Toxic Class 4 according to GOST 12.1.007-76 Occupational safety standards system, 1976.
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