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Antiviral activity of lactoferrin against Potato virus x in vitro and in vivo

Antiviral activity of lactoferrin against Potato virus x in vitro and in vivo

Samah A. Mokbel, Soad H. Taha, Mahmoud M. Abd-El Hamid, Ali H. Hamed

1Virus and Phytoplasma Research Department, Plant Pathology Research Institute, Agricultural Research Center (ARC), Egypt.
2Dairy Science Department, Faculty of Agriculture, Cairo University, Egypt.

ABSTRACT

The effectiveness of lactoferrin against Potato virus x (PVX) in vitro and in vivo have been evaluated. Four concentrations of lactoferrin 100, 250, 500 and 1000 mg/L were examined either in vitro culture medium or in vivo (greenhouse). The presence of the virus was evaluated by ELISA technique. Results demonstrated that application of 1000 mg/L lactoferrin by spraying or combined with tissue culture proved to be an effective method for PVX-inhibition as compared with other concentrations. Also, results of antiviral activity of lactoferrin at concentration 1000 mg/L showed great potential as phytotherapeutic source to produce quality and health plantlets for rapid and large scale in vitro production.

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Journal of Virological Sciences

July

Vol. 3, Iss. 1

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