Clinical, Haematobiochemical, Ultrasonographical, and Ruminal Alterations in Induced Lactic Acidosis with Therapeutic Evaluation in Camels in South Sinai
Clinical, Haematobiochemical, Ultrasonographical, and Ruminal Alterations in Induced Lactic Acidosis with Therapeutic Evaluation in Camels in South Sinai
Mohamed Mohamady Ghanem1*, Yassine Mahmoud Abdelraoof1, Abdelghany Hefnawy Abdelghany2, Eman Abdelhamid El-Ebissy3, Ahmed Ragab Askar4,5, Attia Ahmed Eissa6
ABSTRACT
This study aimed to investigate the effect of induced lactic acidosis in camels on clinical, haemato-biochemical, ultrasonographical and ruminal examinations, and to evaluate therapeutic interference by Rumitone (herbal product). To achieve these objectives, three healthy she camel at Ras Sudr Research Station, belonging to Desert Researcher Center, aged from 8-10 years old and weighting 350- 400 kg were used. Lactic acidosis was induced with oral sucrose (14 gm/ kg BW) for 24hs after which camels were treated with oral Rumitone daily for a week. Clinical examination revealed significant increase (P < 0.05) in body temperature, respiratory rate, and pulse rate, and significant decrease (P < 0.05) in ruminal movement after lactic acid induction. Hematological examination revealed a significant increase (P < 0.05) in RBCs, HB, PCV%, platelets and WBCs after induction of lactic acidosis. Biochemically, the induced lactic acidosis produced significant increase (P < 0.05) in ALT, AST, GGT, urea, creatinine with significant decrease (P < 0.05) in ALP, albumin, globulin, total protein, A/G ratio, Na, Cl, Ca, P and Mg. Examination of ruminal fluid showed a significant increase (P < 0.05) in SAT, MBRT, and a significant decrease (P < 0.05) in ruminal pH, protozoal count and activity. Ultrasonographically, there was significant increase (P < 0.05) in ruminal wall thickness, reticular wall thickness, and small intestine diameter. The content of abomasum and small intestine appeared more echoic. Treatment with Rumitone changed the clinical, hematological, and biochemical alterations toward the reference values. It was concluded that camels are prone to induction of lactic acidosis by sucrose that induced hematobiochemical changes and the Rumitone is a useful therapy in camels affected with acidosis.
Keywords | Camels, Haemato-biochemical, Lactic acidosis, Rumitone, Ultrasonography
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