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Salma Shaheen, Muhammad Jamil Khan, Saleem Jilani

... half of the recommended dose of NPK @ (75:60:30 kg ha-1) with or without EM. In 2009-10, the application of EM with Press mud @ 20 t ha-1 significantly enhanced spinach growth by exhibiting higher average spinach plant height (35 cm), number of leaves (16.4), fresh foliage yields (330 g pot-1), dry foliage yields (32 g pot-1), leaf length (40.5 cm) and leaf area (238.4 mm2) relative to poultry manure, compost or FYM treatments. Similar trend was observed duri...

Muhammad Ashraf Khan1, Hizbullah Khan1, Abid Farid2

... with the virus at field dose (x), 2x dose, and 0.5x dose ranged from 83.2- 87.3%, 87.1- 91.6%, and 83.7- 89.7%, respectively, relative to control eggs treated with water. The parasitism rates by female parasitic wasps emerged from host eggs treated at x dose when parasitoid was during egg, larval, and pupal stages were 21.6, 26.5, and 25.1%, respectivel...

Arshad Ali Khan1, Muhammad Sajid1, Abdur Rab1, Sahib Alam2, Abdul Bari3

...an optimum fertilization dose for obtaining higher yield and improved fruit quality of tomato crop.

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Imdad Sohu1, Allah Wadhayo Gandahi2*, Ghulam Raza Bhutto2, Muhammad Salim Sarki2, Rabail Gandahi3

...n of half of recommended dose of NKP (18-36-10 kg ha-1) in combination with poultry manure or farmyard manure at the rate of 20 t ha-1 was found best combination for higher chickpea crop yields in compare to other levels of fertilizers.

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Ghulam Ali Bajwa and Muhammad Arshad Khan

...luded that urea in split doses and diammonium phosphate in single dose should be applied 3-4 weeks before the commencement of rearing of Mulberry Silkworm Moth for nutritionally rich mulberry foliage.

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Muhammad Nawaz Kandhro*, Habib-Ur-Rehman Memon, Muhammad Ali Ansari, Ahmed Naqi Shah

...e results that Dual Gold dose can be reduced up to 50% in combination with sorghum or sunflower water extracts for effective and environment friendly weed management and enhancing cotton yield.

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Mudasir Irfan Dar*, Fareed Ahmad Khan and Farha Rehman

E-mail | [email protected]

...spective controls at all doses and growth stages observed, attaining maximum with 40 grams Imidacloprid active ingredient per hectare-1 at day 15 after treatment. The antioxidative enzyme activity of SOD, APX and GR showed increasing trend in a dose-dependent manner, attaining maximum at 40 g.a.i ha-1 of Imidacloprid treatment at day 7 after treatment (DAT) followed by 3 and 15 DAT, respectively. On the contrary, the CAT act...

Shahid Ali1, Habib Akbar2, Mohammad Tariq Jan2, Mohammad Jamal Khan3 and Abdul Bari4

...o sub-plots. Recommended dose of fertilizer i.e. N: 150. P2O5: 100. K2O: 100 were applied and standard management practices (inter-culturing, earthing up, and irrigation) were performed. The objectives were to find best planting source, cane portions, setts placement methods and interaction for maximum emergence, visible crop stand leading to yield and yield components. Significant differences were observed among cane portions and setts placement methods for a...

Muhammad Amjad Nadim1*, Mohammad Safdar Baloch1, Ejaz Ahmad Khan1, Abdul Aziz Khakwani1, Kashif Waseem2

...ributes with recommended doses of NPK fertilizers. This treatment (NPK at recommended levels) resulted in higher leaf area index (0.33 and 0.27 [49 days after sowing-DAS] and 2.03 and 2.77 [98-DAS]), crop growth rate (40.42 and 40.96 g m-2 day-1), relative growth rate (88.94 and 84.14 mg g-1 day-1), net assimilation rate (3.58 and 3.89 mg m-2 day-1) and grain yield (4.40 and 5.29 t ha-1) during the years of experimentation. Similar trend was also noted by the ...

 Zar Muhammad and Mohammad Tariq Jan

... half of the recommended dose (75 kg N ha-1) of Urea-N or no Urea-N. Compost, its composition, mineral N and their interactions significantly affected maize yield and yield components over two years average data. Compost application produced more maize ears m-2 (13%), grains ear-1 (28%), 1000 grains weight (14%), biological yield (56%), grain yield (65%) and harvest index (5%) over control. Among varying composition composts, higher grains ear-1(274), 1000 gra...

 Umed Ali Laghari, Ahmed Naqi Shah, Muhammad Nawaz Kandhro, Zia-ul-Hassan, Ghulam Murtaza Jamro and Khalid Hussain Talpur

...and Sel-945) and three K doses (0, 10 and 20 kg K ha-1). The results revealed that K nutrition and genotypic variation significantly (p<0.05) determined the yield of grass pea. However, their interaction remained non-significant for all the traits of grass pea under study. As expected, the increasing rate of K significantly (p<0.05) increased various growth traits and yield of grass pea genotypes. The crop supplied with 20 kg K2O ha-1 produced maximum br...

Sayeda Sarah and Muhammad Ibrar

...in all hybrids. Higher P doses declined the sporulation and colonization. There was total seven AMF species that were observed and recorded. The dominant genus was Acaulospora which was followed by Glomus, Sclerocystis and Gigaspora. The average AMF spore density ranged from 56-260 spores/100g soil while root colonization ranged from 32-100%. Mycorrhizal enhancement regarding AMF spores density and root colonization ranked asRP0>RP1>RP2>RP3 in all hyb...

Felwa A. Thagfan1, Mohamed A. Dkhil1,2* and Saleh Al-Quraishy1

...jejunum. Three different doses, 300, 600 and 900 mg/kg were used after infection of mice with sporulated oocysts. A dose of 300 mg/kg reduced the number of oocyst output in mice faeces by about 56.8 % and also improved the body weight. In addition, the root extract decreased the number of parasitic stages and the number of goblet cells in the jejunal villi in the infected mice. Moreover, the expression of the goblet cell muc...

Laila M. Fadda1, Nouf M. Al-Rasheed1, Iman H. Hasan1, Hanaa M. Ali2,3*, Nawal M. Al-Rasheed1,4, Musaed Al-Fayez5, Aly M. Ahmed5, Nada Almutlaq1, Nehal Qasem1 and Reem Khalaf1

...Acetaminophen (APAP) overdose depleted glutathione (GSH) which lead to liver dysfunction and hence hepatotoxicity. N-acetylcysteine (NAC) is the best antidote for APAP but may induce a variety of side effects. This study was designed to compare the potential impact of NAC with that of Thymoquinone (THQ), and/or Curcumin (CUR) either alone or in combination on liver injury induced by inflammation, oxidative stress in response to APAP toxicity in rats. Serum ami...

Shagufta Jabeen1, Muhammad Saqlain Raja1, Sadia Saeed1, Muhammad Mobeen Zafar1, Rizwana Abdul Ghani1, Abid Mahmood1, Muhammad Fiaz2, Pakeeza Arzoo Shiaq1, Shahid Mahmood Baig3, S.M. Saqlan Naqvi1 and Ghazala Kaukab Raja1

...actors (drug route, drug dose) have bearing upon heroin addiction was collected. Descriptive and inferential statistics were used for data analysis. Early age of addiction onset, low literacy rate, peer pressure, occupation type, and stress are among risk factors increasing susceptibility towards heroin addiction in our studied cohort. Drug abuse initiated at an early age seems to trigger transition to heroin addiction under the influence of environmental risk...

Sadiq Hussain, Muhammad Sharif, Sarmad Khan, Fazli Wahid, Hina Nihar, Wiqar Ahmad, Imran Khan, Nadeem Haider and Tabassum Yaseen

...tration. The recommended dose of N @ 120 kg ha-1 was applied in the form of vermicompost and urea, while K was applied in the form of sulphate of potash. Spores of mycorrhiza were isolated from fresh growing crop of berseem at the University research farm and used as inoculums in this experiment. Results showed the maximum grain yield of 15.09 and 14.7 g pot-1, highest total dry matter yield of 36.3 g and 36 g pot-1, maximum roots dry weight of 5.6 and 5.41g p...

Muhammad Zahid1, Muhammad Hamid Bashir1*, Bilal Saeed Khan1 and Muhammad Shahid2

...icides at field relevant doses after 144 h respectively. Missing mites data indicated repellency due to pesticides, was highest at the start of experiment, and then these acclimatized on leaf discs. Thiacloprid having lowest LC50 value 295 and proved toxic for the predator while diafenthiuron and pyriproxyfen have higher values. The findings of the study revealed that among five tested pesticides chlorfenapyr and thiacloprid proved moderately harmful for N.bar...

 Ali Murad Rahoo1,2, Tariq Mukhtar3,*, Simon R. Gowen1, Rehana Kanwal Rahoo4 and Shaukat Ibrahim Abro5

...feltiae emerged at 50 IJ dose followed by 100 IJ. The emergence of IJ decreased significantly at the dose of 200 IJ and then increased with 400 IJ dose. The minimum number of juveniles emerged at the dose of 200 IJ. The relationship between inoculation dose and emergence of IJ by using both methods was non-significant....

Ecevit Eyduran1, Daniel Zaborski2*, Abdul Waheed3, Senol Celik4, Koksal Karadas5 and Wilhelm Grzesiak2

...andards, favourable drug doses and required feed amount for animals. The ascertainment of the body measurements associated with BW using data mining algorithms can be considered as an indirect selection criterion for future goat breeding studies. 

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Muhammad Sohail1,*, Muhammad Naeem Khan1, Naureen Aziz Qureshi2 and Abdul Shakoor Chaudhry3

...o detect DNA damage. Low doses (120 µg L-1) of each metal induced significantly higher levels of DNA strands breaks as compared to medium dose (240 µg L-1) and very low levels of DNA damaged was observed at high dose (360 µg L-1). Cu and Pb showed significantly higher value of % of tail DNA (56.74±1.81, 47.36±1.23) and comet tail length (41.30±0.758, ...

Muhammad Hafeez-ur-Rehman1, Farzana Abbas1, Muhammad Ashraf1, Naeem Tariq Narejo2, Khalid Javed Iqbal3, Ghulam Abbas4* and Syedah Andleeb5

...le fish was injected 1st dose with ovaprim + HCG (0.3+0.3ml) and female fish was given 2nd dose after 24 hrs of intervals with ovaprim (0.2ml), while 1st dose ovaprim (0.7ml)+HCG (1.0ml) and 2nd dose ovaprim (0.7ml) was given to the females. The treatment which was given 35% protein diet received 1st HCG+HMG (0.3+0.3ml) and ovaprim (0.2ml) to males and o...

Faiqah Ramzan*1 and Muhammad Haris Ramzan2

...ulated by androgens. As, dose dependent degeneration of prostate gland has been described following intraperitoneal kisspeptin treatment. However, effects of kisspeptin administration on the levels of prostatic citric acid remain elusive till date. The present study, therefore, addresses the effects of 12 day administration of kisspeptin on prostatic citric acid levels in male mice. Kisspeptin-10 was administered intraperitoneally in different dosage concentra...

Muhammad Shafiq and Tahir Maqsood

...olution having diverse B doses (0, 0.01, 0.03 , 0.05 , 0.07, 0.09, 0.11, 0.13,0.15 and 0.17 mg B L-1). Freundlich and Langmuir adsorption models were applied to the data to check the sorption of B on sandy clay loam soil. Freundlich model depicted superior fitness of the sorption (r2=0.99) statistics than Langmuir model (r2=0.75). Ten B treatments (0, 0.47, 0.81, 1.42, 1.57, 1.95, 2.35, 2.66, 3.1, 3.3 kg ha-1) were applied with recommended N, P and K

Sidra-Tul-Muntaha1, Muhammad Sagheer1*, Mansoor-ul-Hasan1 and Shahbaz Talib Sahi2

...respectively. At highest dose rates, more than 90% repellency was recorded with both A. indica and deltamethrin. Upto 80% progeny inhibition was caused by the extract of A. indica. While more than 50% population of C. chinensis was inhibited with deltamethrin. More pronounced results were obtained at high concentrations. Plants were effective in order of Azadirachta indica > Melia azadirach > Pegnum hermala > Salsola baryosma> zingiber officinale; ...

Zaffar Malik, Moazzam Jamil, Ghulam Hassan Abassi, Muhammmad Nafees, Muhammad Rafey and Muhammad Kamran

... vertisols. However, low doses (2%) of straw biochar were more beneficial by keeping in view the availability and economic level of the landholders.

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Pinar Oztopcu-Vatan1, Gokhan Kus2, Emine Inan3, Melek Gunindi Korkut3, Selda Kabadere4,* and Ruhi Uyar4
... treatment with the same dose and time duration decreased the number of surviving cells by 87 %. Treatments with 150, 200 and 250 µM licofelone caused early apoptotic cell rates of 4, 15 and 24 % for 24 h and 6, 13 and 24 % for 48 h, respectively. In addition, 150, 200 and 250 µM of 5-Fluorouracil resulted early apoptotic cell values of 13, 12, and 11 % for 24 h and 18, 22 and 16 % for 48 h. This study revealed that licofelone possesses
Nagwan F. Zahran, Ali F. Hamza and Rehab M. Sayed* 
...izing and substerilizing doses of gamma radiation. The effect of gamma rays on the DNA patterns of adult males showed alterations from the control. Exposure to radiation caused very frequently the appearance of some extra bands and the deficiency of others in the RAPD-PCR amplification patterns of the irradiated insects. 
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Wesam Hasan Mohamed Mady 1*, Bing Liu2, Dong Huang2, A. Arafa1, M.K. Hassan1, M.M. Aly1, Pucheng Chen2, Yongping Jiang2* and Hualan Chen2

...) two weeks post-booster dose. The chickens were then challenged using homogenous AI H9N2 strain. During the course of infections, oropharyngeal and cloacal swabs were collected from all chickens at 3, 5 and 7 days post-challenge (p.c.) for virus titration in eggs. Data indicated that all chickens vaccinated with pCA-Egy-H9 were fully protected without clinical signs and virus shedding. Our results revealed that the pCA-Egy-H9 plasmid DNA vaccine could induce ...
Muhammad Tahirand Memoona Shehzadi*
...ilizer, half recommended dose of fertilizer and full recommended dose of chemical fertilizer) and Plant Growth Promoting Rhizobacteria (PGPR) (No PGPR, PGPR-1, PGPR-2 and PGPR-1 + PGPR-2). The PGPR used in this study were pre-isolated and characterized, taken from soil microbiology and biochemistry laboratory, Institute of Soil and Environmental Sciences (ISES), University of Agriculture Faisalabad. In this experiment Random...

A. K.Bhattacherjee and B. K. Pandey

Dissipation of carbendazim in mango after pre- and post-harvest treatments
...rom 0.05 and 0.1 percent doses, respectively. The corresponding values in fruit pulp after same days of storage were 0.51 and 1.05 mg kg . The residual half-life values of carbendazim in whole fruit were calculated as 4 and 3 days at both the concentrations from pre harvest spray and post harvest dip treatment, respectively. Pre and post harvest interval of 3 and 7 days were suggested from 0.05 and 0.1 percent concentrations. [email protected] percent was found...

Abhijit Ghosal and M. L. Chatterjee

Bioefficacy of imidacloprid 17.8 SL against whitefly, Bemisia tabaci (Gennadius) in brinjal
...r, imidacloprid at lower doses showed nearly similar results. The other neonicotinoid, thiamethoxam also provided similar levels of protection as that of imidacloprid. The conventional insecticide, methyl demeton (125 g a.i./ha) was less effective.

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D.K. Hazra, Megha Pant, S.K. Raza and P. K. Patanjali

 

Formulation technology: key parameters for food safety with respect to agrochemicals use in crop protection
...se of their increased in dose rate or repeated applications to get desired bioefficacy which lead to accumulation of pesticide residues in food commodities along with environmental pollution. Conventional formulations, because of their characteristics i.e. dustiness and use of volatile organic solvents in their preparation maximize several problems like health haz-ards and environmental pollution etc. With the increasing awareness of toxic effects of conventio...

Dhananjoy Mandal 2K. Baral 3M. K. Dasgupta

Developing site-specific appropriate precision agriculture
...ment at varied pesticide doses depending on varied soil pest population intensity and spatial distribution. Often it ends up in reducing the quantum of a pesticide threatened with withdrawal. We understand Appropriate PA (Appropriate Precision Agriculture, APA) as Site-Specific Appropriate Precision Agriculture (SSAPA) applied to cropping system management with geoinformatics and agriinformatics as may be available of land, soil, including its nutrient content...
Beenish Zahid1,*, Asim Aslam2, Zafar Iqbal Chaudhry2 and Raheela Akhtar2
...ere challenged with same dose at 2nd week of age. While the group C and D was unchallenged control containing commercial and SAN chicks. The Blood samples were collected from group A, B, C and D on 3rd, 5th and 7th day of post infection for biochemical analysis. The Albumin and total protein values were significantly low (P<0.05) in infected groups A and B as compared to control groups C and D on 5th an...
Madeeha Arshad1, Naveed Ahmad2,*, Muhammad Khalid3, Asmatullah1, Mohammad Tahir2, Khadija Naveed1 and Asia Iqbal4
...nic effects of different doses of Cr VI, administered to pregnant mice. LD50 of Cr VI, was calculated as 88mg/kg of B.W in pregnant mice. Among 05 groups of pregnant females (10 females in each group), three were treated with 50%, 25% and 12.5% of the LD50 of Cr VI, respectively, with one control and one vehicle control group. Fetuses were recovered on 18th day of gestation and fixed for morphometric and morphological studies. ...
Mehwish Faheem1,*, Saba Khaliq2 and Khalid Parvez Lone2
... non-monotonic, biphasic dose response to BPA. 
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Muhammad Mansoor1, Amanullah1, Zafar Islam2*,Sher Muhammad3, Muhammad Umair4, Mehmood Ayaz5, Asghar Ali Khan6, Muhammad Asif2 and Ya Sakina3
... row spacing, fertilizer dose @ 20:50 kg ha-1 N:P2O5 and inoculation with rhizobium strain Vm M1 were optimal for its maximum yield. Inqalab Mung outclassed among all candidate lines included in National Uniform Yield Trial (NUYT)- 2007 with an average yield of 1092 kg ha-1 at 12 locations across country, with highest grain yield of 3620 kg ha-1 at Agricultual Research Station ARS, Mingora, Swa...

Murad Ali1, Farmanullah Khan1, Wiqar Ahmad2* and Imran Khan1

...ermination of a suitable dose from either source that could beneficially and easily combine to give maximum output still needs lots of research. The experiment was conducted during wheat season 2014-15 on a selected water eroded site in District Swabi. Fourteen treatments viz the control (T1), recommended dose (RD) (120:90:60 kg ha-1 N: P2O5: K2O. T2), four combinations of farmyard manure (FYM) i.e 20, 15, 10 and 5 t ha-1 wi...
Sumaira Maqsood1,*, Muhammad Afzal1, Muhammad Anjum Aqueel1, Abu Bakar Muhammad Raza1,Waqas Wakil2 andMuhammad Hussnain Babar3

 

...nation with NPV at lower dose showed synergistic interaction (CTF≥20). While rest of the combination showed additive effect (CTF≤20). Integration of NPV and flubendiamide proved more fatal at higher concentrations than the individual application at lower concentration for pupation and adult emergence of S. litura. Apart from untreated larvae (control) maximum pupation (66.01±1.32 and 73.95±1.28 %) and adult emergence (61.87±1....
Talha Nazir1,2,*, Muhammad Dildar Gogi2, Muhammad Zeeshan Majeed1, Waheed ul Hassan2, Abdul Hanan2 and Muhammad Jalal Arif
... their field recommended dose rates upon attainment of ETLs of most of the sucking insect pests. Data regarding insect populations were recorded 3 and 7 day post treatment. Results revealed that Confidor proved to be most effective systemic insecticide against all insect pests, followed by Pouch, Senator, Blaster, Bugatti and Jozer. However, Confidor, Jozer, Bugatti, Blaster and Senator showed a top-down effect on beneficial insects causing 50–90% reduct...
Saleem Khan1, Amir Hamza2, Farhadullah Khan3, M. Subhan4, Aziz Khan1, Irfan Ali Shah1, Shakirullah Khan Shakir3*
... and 25 Kilo Radium (KR) doses sourced from 60Co. The irradiated seed samples were assumed treated seeds while non-irradiated seeds of each genotype were used as control. Field experiment was conducted in randomized complete block design (RCBD) in three replicates in the green house. Radiation effects were observed on some agronomic traits like Plant height, Number of branches plant-1, number of bolls plant-1, Fiber Fineness an...
Muhammad Abu Bakar1, Muhammad Anjum Aqueel1, Abu Bakar Muhammad Raza1, Muhammad Irfan Ullah1,*, Muhammad Arshad1, Mubasshir Sohail1,2 and Jaime Molina-Ochoa3,4
...orange oil) at different doses against percent mortality of Varroa mites. The essential oils were applied at two different doses (2.5ml and 5ml) and percent mortality data was recorded after 12, 24, 48 and 72 h of the application. As seen from results, all essential oils gave satisfactory control of Varroa mites except orange oil. The percent mortality was observed higher in eucalyptus oil (76.13%) at 2.5ml

Sanjukta Chakrabarti1, Colin J. Barrow2, Rupinder K. Kanwar3, Venkata Ramana1*, Rakesh N. Veedu4,5 and Jagat R. Kanwar3* 

...istered naked and at low dose. As these are only our preliminary studies, a detailed investigation is planned using multiple doses, chitosan nanoparticle conjugated aptamer inline with the previous report on RNV66, and an approved VEGF inhibitor Avastin. Overall, the findings highlight that VEGFR1(D1-D3)-Fc can also serve as a potential anti-angiogenic molecule. 

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Müge Aliye Hekimoğlu*, Cüneyt Süzer,Şahin Saka andKürşat Firat
...erm application the safe dose for clownfish was 0.4 ml/l phenoxyethanol and 1 ml/l clove oil. For swordtail fish, the ideal amount of phenoxyethanol was 5 ml/l and 6 ml/l clove oil. These safe doses reduce handling stress and mortality.
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Muhammad Qaisar Nawaz
...d 150 % of N recommended dose i.e. 150kg ha-) were tested. Recommended dose of PK fertilizer (85-60 PK kg ha-1) was used uniformly with experimental N rates. Data on plant height (132.00 cm), number of plants (91.33 m-2), number of tillers (146.00 m-2), number of leaves tillers-1 (5.66), total dry matter (17.70 t ha-1) and fodder yield (60.90 t ha-1...

Muhammad Asad1, Safdar Ali1, Muhammad Ramzan Ansar2, Ijaz Ahmad3*, Muhammad Suhaib4 and Muhammad Khubaib Abuzar5 

...nce with three different doses each viz:,Ally max @ 34.58, 46.11 and 23.04 g ha-1, Lihua @ 53.34, 72.4 and 36.23 g ha-1, and Wheat Star @ 370.5, 494 and 247 g ha-1 and Buctril super 60% EC @ 741, 988 and 494 ml ha-1. An untreated control and hand weeded plot was also included in the trial. Wheat variety AUR-2009 was sown as a test crop and the herbicide was applied 65 days after sowing. All herbicides were sprayed as post-emergence. The best weed control was a...
Faiza Ambreen*1 and Muhammad Javed2
...ged cells. In general, a dose dependent response was observed in fish erythrocytes with induction of maximum DNA damage at highest concentration (1/3rd of LC50) of pesticide mixture. Statistically significant effects for both concentrations and time of exposure in terms of DNA damage were observed in treated fish as compared to control group. The results supported the use of Comet assay for evaluating the toxicity of pollutants which may ...

Naila Riaz1 , Hafiz Muhammad Tahir2* , Khizar Samiullah3

...1.5µl of the venom dose. However, at the same venom dose, 100% mortality was achieved at 8 hr posttreatment when applied topically. Similarly, oral administration of 1µl and 0.5µl venom caused 100% mortality at 8 hr post-treatment compared to 10 hr and 12 hr post-treatment of topical application, respectively. It is concluded that oral treatment of venom was more efficient compared to its topical treatment ...

Soraya Khosravian Dehordi*, Abdolnaser Mohebbi and Kahin Shahanipour

...o-Se (0.1mg/kg) alone as dose, group II selenite odium (0.1mg Se/kg) alone, group III Cd chloride (300mg/250cc), group IV Cd along with nano-Se, group V Cd along with selenite sodium and group VI (control) given (1 ml) saline. All doses was orally (gavage) given to rates.Protein carbonyls (PC) andthiobarbituric acid reactive substances (TBARS),superoxide dismutase (SOD) glutathione peroxidase (GPx) and catalase (CAT) values ...

Imran Khan*, Zahir Shah, Wiqar Ahmad, Farmanullah Khan and Muhammad Sharif 

...g ha-1), NPK recommended dose (RD, 120:90:60 N:P2O5:K2O kg ha-1), 5, 10, 15 and 20 t FYM alone (FYM5,10,15,20) and 5, 10 and 15 t ha-1 FYM in combination with 75, 50 and 25% of the recommended NPK (INM5:75, 10:50, 15:25) in sub plot (5 * 3 m2) and tillage practices (TP) in main plots. Tillage practices effect on micronutrient status was significant, however, variations in physical properties were negligible. The Zn, Cu, Fe and Mn contents were 23, 11, 38 and 3...

Attia Anwar1, Sajida Malik2*, Zobia Usman1 and Sadia Chiragh3 

...erine hydrochloride with dose of 75 mg/kg body weight/day. 24 weeks post-treatment, blood samples were collected by cardiac puncture from both groups and tested for Hb (%), WBC, RBC and platelet counts, SGPT, alkaline phosphatse, serum uric acid, blood urea and serum creatinine. All the numerical data were expressed as mean± SD. The values in two groups were analyzed with help of unpaired t-test. A p-value ˂ 0.05 was considered significant. After 2...
Muhammad Aqeel Sarwar1*, Abid Ali2, Manzoor Hussain2, Saadia3, Muhammad Khubaib Abuzar4, Ijaz Ahmad5 and Sohail Latif6
...2)100% recommended dose of NPK, (F3) 75% recommended dose of NPK + 1.5 t ha-1 poultry manure(PM), (F4) 75% of recommended dose of NPK +3 t ha-1 farmyard manure (FYM) and(F5) 75% of recommended dose of NPK + 4.5 t ha-1 press-mud (PrM) along with seed inoculants (I1) Azos...
Alim-un-Nisa1*, Sajila Hina1, Sania Mazhar1, Imran Kalim1, Ijaz Ahmad1, Naseem Zahra1, Shahid Masood1, Muhammad Khalid Saeed1, Qurat-ul-Ain Syed1 and Maida Asif2
...ial activity. The lethal dose and toxicity determination of the color extracted from marigold showed that it is safe for consumption as no clinical symptoms were observed in rabbits after giving the maximum dose of 1000ml of color.
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Parvez Khaliq*, Muhammad Azim Malik** and M. Aslam Gill***

EFFECT OF CROPPING SYSTEMS, TILLAGE PRACTICES AND FERTILIZER TREATMENTS ON WHEAT STAND ESTABLISHMENT UNDER RAINFED CONDITIONS
... treatments {recommended dose of fertilizer (F); fertilizer + manure (F+FYM); manure only (FYM) and control (C)} did not show significant effect on both emergence and emergence rate index. Overall, significantly (P<0.05) higher residual soil moisture content was available in fallow-wheat system which resulted in better wheat emergence. This ultimately resulted in vigorous crop stand establishment. The biomass harvest observed at 2-3 leaf stage in the fallow...

Khalid Mahmood Aujla, Sajida Taj*, Khalid Mahmood** and Nadeem Akmal*

...er below the recommended doses, higher prices of inputs such as seed, fertilizer, diesel, electricity and less wheat prices during 2006-07 and late announcement of the minimum guaranteed wheat price for 2007-08 were the main reasons of lower wheat production in 2007-08. To enhance the wheat yield, farmers were of the view that the timely availability of quality inputs (seed, fertilizers) at reasonable prices, canal water supply at critical stages of plant grow...

 Ashiq Saleem, Habib Iqbal Javed, Rashid Saleem,* Muhammad Ansar** and M. Amir Zia*

...gate the effect of split doses of potash fertilizer on maize and sorghum. Potash fertilizer was applied @ 0, 60 and 120 kgha-1 K2O as single, two split and three split doses at planting, after one month and after two months of planting. The experiment consisted of seven levels (0, 60, 30 + 30, 20 + 20 +20, 120, 60 +60 and 40 + 40 + 40 kgha-1). Grain yield in maize and sorghum showed positive relationship with increase in pot...
Amtul Jamil Sami1,*, Sehrish Bilal1, Madeeha Khalid1, Muhammad Tahir Nazir1 and A.R. Shakoori2

 

.../i> at larval stages, in dose dependent and time dependent manner. LC50 was determined to be 0.7ppm. To investigate the different effects of saponins on A. mellifera and T. castaneum AChE, computational approach was employed. For this purpose a dissection of 3-D model of A. mellifera and T. castaneum AChE enzyme was studied which showed that change in amino acid sequence of primary structure of enzyme exists at the saponin binding s...
Nazish Shaukat1, Muhammad Javed1,Faiza Ambreen2* and Fariha Latif1
... rohita to different doses of PbCl2 viz. 96-h, 2/3rd, 1/4th and 1/5th of LC50, separately, for 30 days and compared with control group. After 30 days, fish was sacrificed and their gills and liver isolated to determine the effect of PbCl2 on peroxidase activity. Activity of peroxidase enzyme in metal stressed fish was compared with control. The physico-chemical parameters of the test ...

 Nazakat Nawaz, Malik Shah Nawaz*, Nasir M. Cheema** and Mubashir A. Khan*

Corresponding author:[email protected]

ZINC AND IRON APPLICATION TO OPTIMIZE SEED YIELD OF MUSTARD
...), respectively. A basal dose of 90N and 60P kg ha was applied, in the form of Urea and triple super phosphate (TSP) with Zn and Fe. The increase in -1 Zn and Fe fertility from 0-1.5 to 5-1.5 kg ha increased yield of BARD-1. The maximum yield response was recorded when 5 kg ha-1 -1 Zn and 1.5 kg ha Fe were applied. Beyond this level, no further increase in yield was recorded in any mustard traits. A positive correlation was recorded between seed yield -1 -1 an...

 Parvez Khaliq*, Muhammad Azim Malik**, M. Aslam Gill*** and
Nasir M. Cheema*

Corresponding author: [email protected]

EFFECT OF TILLAGE AND FERTILIZER TREATMENTS ON MAIZE FODDER YIELD UNDER RAINFED CONDITIONS OF PAKISTAN
...tments i.e., recommended dose of fertilizer (RF), farm yard manure (FYM) and recommended dose of fertilizer plus farmyard manure (RF+FYM) on maize fodder yield was studied under rainfed conditions of Pakistan. It was observed -2 that the emergence count m , maize fodder biomass, plant height, number of leaves per plant and maize fodder yield enhanced, with the application of RF+FYM. However, the effect of FYM+RF and recommen...

 Parvez Khaliq*, Azim Malik**, Nasir Mahmood Cheema* and Muhammad Umair***

ECONOMICS OF WHEAT BASED CROPPING SYSTEMS IN RAINFED AREAS OF PAKISTAN
...control (C), recommended dose of fertilizer for each crop (F), farmyard manure (FYM) @ -1 5 tha . The recommended doses of fertilizer for individual crop with FYM (F+FYM) were also included in the study to know their impact on the crops yield in the cropping systems. Economic analysis of the data revealed that the traditional wheat-fallow-wheat cropping system could be economically replaced with wheat-maize fodder-wheat crop...

 Safdar Ali, Sahiba, M. Azim Malik, Fayyaz-ul-Hassan and M. Ansar*

GROWTH OF RAINFED FODDER MAIZE UNDER DIFFERENT LEVELS OF NITROGEN AND PHOSPHORUS
... nitrogen and phosphorus doses under sub-humid rainfed conditions during 2009 at PMAS-Arid Agriculture University, Rawalpindi, Pakistan. The annual rainfall at the experimental site during 2009 was 685.9 mm. The -1 experimental soil was of loamy texture having E.C. of 0.48 dscm , pH 7.7, -1 organic matter 0.65%, saturation 30%, available phosphorus 5.7 mg kg -1 and available potassium 78 mg kg . Maize cv. Sargodha-2002 was sown in randomized complete block des...

 Arshad Ali, Muhammad Arshadullah, Syed Ishtiaq Hyder, Imdad Ali Mahmood and Badar-uz-Zaman*

RICE PRODUCTIVITY AND SOIL HEALTH AS AFFECTED BY WHEAT RESIDUE INCORPORATION ALONG WITH NITROGEN STARTER DOSE UNDER SALT-AFFECTED SOIL
...with different N starter doses -1 (0, 30, 60 and 90 kg N ha ) on rice (Supper basmati) production and soil health at MK Farm, Farooqabad, district Sheikhupura under saline sodic -1 soil (ECe=5.65 dS m , pH=8.57and SAR=19.38) during 2010. Treatments were arranged in RCBD with three replications. The crop was harvested at maturity, data on tillering, plant height, spike length, number of grains -1 spike , 1000-grain weight, straw and paddy yields were recorded. ...

 Shafique Qadir Memon*, Muhamamd Safar Mirjat, Abdul Quadir Mughal** Nadeem Amjad***, Muhammad Azhar Saeed, Shabbir Kalwar, Asif Ali Mirani and Habib Iqbal Javed****

TILLAGE AND NPK EFFECT ON GROWTH AND YIELD OF SPRING MAIZE IN ISLAMABAD, PAKISTAN
...tillage with recommended dose of NPK performed best and provided more vegetative growth and grain yield in maize. However, poor-resource farmers can use the medium level of NPK @ -1 150-75-75 kg ha for getting an economical and successful maize crop.

...

 Muhammad Sohail*, Imtiaz Hussain*, Riaz-ud-din*, Syed Haider Abbas*, Maqsood Qamar* and Muhammad Noman*

EFFECT OF SPLIT N FERTILIZER APPLICATION ON PHYSIOAGRONOMIC TRAITS OF WHEAT (TRITICUM AESTIVUM L.) UNDER RAINFED CONDITIONS
...ers usually apply full N dose at seeding. However, winter showers during vegetative growth period provide an opportunity to apply N in split doses. Study was conducted to find out appropriate N rate and application method to enhance wheat productivity. -1 Three N rates i.e., 60, 90, and 120 kg ha and three application methods i.e. full basal N dose at planting and N application in two and ...

 Abdul Rehman Roonjho*, Waseem A. Gillani**, Awais Rasool**, Naheed Akhtar**, Tariq Mahmood**, Arsalan A.***, M. Afzal*, Iqbal Khan* , M. Asghar Ranjha**** , M. Irfan**** and Javed Khan**

REPELLENCY EFFECTS OF DIFFERENT PLANT EXTRACTS TO COTTON MEALY BUG, TINSLEY (HEMIPTERA: PSEUDOCOCCIDAE)
...lency (72.5%) at 500 ppm dose. The lowest average repellency (26.3 %) was observed in acetone extract of at 500 ppm dose.

...

 Shafique Qadir Memon*, Nadeem Amjad**, Muhammad Safar Mirjat***, Abdul Quadir Mughal***, Khalil Ahmad Ibupoto***, Shabbir Ahmad Kalwar****, Asif Ali Mirani**** and Muhammad Azhar Saeed****

EFFECT OF TILLAGE AND USE OF ORGANIC AND INORGANIC FERTILIZERS ON GROWTH AND YIELD COMPONENTS OF MAIZE
...tillage with recommended dose of organic and inorganic fertilizer performed best and provided more vegetative growth, grain yield and dry matter in maize. Residual effects and supplemental fertilizer application in maize production were greater than fresh maize production.

...

 Muhammad Ali*, Ghulam Mustafa Sajid**, M. Faisal Anwar Malik*** and Kalimullah****

ESTABLISHMENT OF IN VITRO CULTURE OF GRAPES
...useful in optimizing the dose and duration of the treatment of grape explants with the surface disinfectant.

...

 Muhammad Ayub*, Rizwan Maqbool*, Muhammad Tahir*, Zoaib Aslam*, Muhammad Ather Nadeem* and Muhammad Ibrahim**

IMPROVED GROWTH, SEED YIELD AND QUALITY OF FENNEL (FOENICULUM VULGARE MILL.) THROUGH SOIL APPLIED NITROGEN AND PHOSPHORUS
...2011-2012. Fertilizer NP dose (90:45 kg -1 ha ) increased plant height by 44%, number of leaves per plant by 76%, 1000 seed weight by 44%, biological yield by 50%, seed yield by 296%, harvest index by 162% and protein content by 6%. However, fertilizer NP -1 (90:45 kg ha ) decreased oil content by 26%. Therefore, addition of NP fertilizer had the potential to increase fennel seed yield, but reduce oil content, under Faisalabad conditions.

...

 Riaz Hussain*, Muhammad Riaz**, Mushtaq A. Saleem*** and Muhammad Ishaque Mastoi**

BIOCHEMICAL ABNORMALITIES INDUCED BY ABAMECTIN IN SIXTH INSTAR LARVAE OF THE RED FLOUR BEETLE, TRIBOLIUM CASTANEUM (HERBST)
... non-significant at both doses in the two strains. In PAK strain larvae, the TE activity was inhibited with depletion of total protein contents and elevation of FAA contents. In FSS-II larvae, the effect of abamectin on levels of α-amylase, glucoamylase, AkP, total protein and soluble protein remained non-significant. The activities of TE and AcP were reduced at both doses, while activities/levels of CE reduced at LC a...

 Doulat Baig*, Fida Mohammad Abbasi*, Habib Ahmed*, Maqsood Qamar** and Muhammad Ayub Khan**

RESPONSE OF SUNFLOWER HYBRIDS TO DIFFERENT NITROGEN LEVELS FOR PHYSIOLOGICAL AND AGRONOMICAL TRAITS UNDER FIELD CONDITIONS
...application of different doses of N can boost up the yield in both sunflower hybrids SMH-0907 and SMH-0917. These findings could be helpful in rationalizing most valuable inputs such as nitrogen in sunflower crop. It can be deduced that the –1 application of 180 kg N ha can provide the best combination for good yield in sunflower crop under the prevailing humid conditions of Pakistan.

...

 Muhammad Farrukh Saleem*, Munir Ahmad*, Shakeel Ahmad Anjum*, Muhammad Aown Sammar Raza** and Abdul Shakoor*

EFFECT OF TOPPING UNDER DIFFERENT NITROGEN LEVELS ON EARLINESS AND YIELD OF COTTON
...ce by topping provided N dose is monitored.

...

 Muneeb Zafar*, Tahir Mehmood**, Irfan Ahmad Baig**, Abdul Saboor** Mazher Abbas***, Shumaila Sadiq** and Khalid Mahmood****

ANALYTICAL DIAGNOSTICS OF NON-OPTIMAL USE OF PESTICIDES AND HEALTH HAZARDS FOR VEGETABLE PICKERS
...her than the recommended dose. Health cost function was significantly different from zero as 2 indicated by F-stat (32.18) and it is also supported by R that about 70% variation in health cost is explained by medication accompanied by productivity loss (Rs. 223), precautionary measure (Rs. 134), attended person cost (Rs. 14) and traveling expenditures (Rs. 16). Hence, strict legislation is required to overcome the availability of hazardous pesticides and to ke...
Ali Murad Rahoo1,*, Tariq Mukhtar2, Ali Murad Jakhar3, Rehana Kanwal Rahoo3
...ophora. The inoculum dose also had an influence on the numbers of nematodes recovered. There were significantly greater numbers of S. feltiae in the 50 and 500 IJ treatments than the 10 IJ dose. On the other hand, the lowest dose of H. bacteriophora did not yield any IJ. Similarly, days did not affect the recovery of nematodes from T. molitor cadavers. However, thi...
Saba Parveen Samo1, Moolchand Malhi1,*, Javed Gadahi2, Yan Lei3, Allah Bux Kaciwal1 and Saeed Ahmed Soomro1
...lenium yeast (SY) at the dose rate of 0.3 mg/kg.diet for 8 weeks. The results showed that the weights (% of empty body weight) of rumen (4.18 ± 0.30 vs 3.49 ± 0.10); duodenum (0.32 ± 0.01 vs 0.27 ± 0.01); colon (1.14 ± 0.03 vs 1.06 ± 0.01), caecum (0.62 ± 0.03 vs 0.57 ± 0.01) and the whole large intestine (2.44 ± 0.04 vs 2.32 ± 0.03) significantly increased (P < 0.05) in B compared to A. ...
Kaori Sasaoka1, Takahiro Kataoka1, Norie Kanzaki1, Yusuke Kobashi1, Akihiro Sakoda2, Yuu Ishimori2 and Kiyonori Yamaoka1,*
...termined the appropriate dose of CDDP combined with radon inhalation for highly radiosensitive mice. CDDP was administered at 20 mg/kg weight to C57BL/6J and BALB/c mice after radon inhalation at 1000 Bq/m3 and 2000 Bq/m3 for 24 h. Radon inhalation had a slight positive effect against CDDP toxicity in C57BL/6J mice with respect to improved hair condition, whereas radon inhalation exacerbated CDDP-induced toxicity in BALB/c mice, such as a...
Muhammad Tariq Zahid1, Farah Rauf Shakoori2, Soumble Zulfiqar3, Khalid A. Al-Ghanim4 and Abdul Rauf Shakoori3,4*
.... The maximum resistance dose of copper for T. farahensis was found to be 8, 9 and 80 µg/ml in wheat grain medium, Bold-basal salt medium and modified Neff’s medium, respectively. T. farahensis exhibited significant copper storage ability removing 54.9 % copper from medium within 96 h of 30 µg/ml copper stress. The maximum uptake rate was observed within 30 min of copper administration in response to 5-100 µg Cu++
Shagufta Andleeb*1, Shabana Shaukat1, Chaman Ara2
...malities by a sub-lethal dose of cadmium chloride and protective role of garlic (Allium sativum), to minimize the intensity of these toxicities. For this purpose, fertilized eggs of Gallus domesticus were randomly divided into four groups of forty eggs each. Control group was intact and untreated. Eggs of one group were injected with a sub-lethal dose of cadmium chloride (1.5 µg/egg) in albumin on 7t...
Syeda Madiha, Zehra Batool, Saiqa Tabassum, Laraib Liaquat, Sadia Sadir, Tahira Perveen and Saida Haider*

 

...ed subcutaneously at the dose of 1.5 mg/kg for 8 days. Supplementation of curcumin (100 mg/kg/day, p.o.) was started before 15 days of rotenone injection. The effects of curcumin pre-treatment were evaluated by different motor behavioral parameters (pole test, Kondziela’s inverted screen test, inclined plane test, open field test, beam walking test and footprint test). Biochemical and neurochemical alterations were also monitored. Pre-treatment with curc...
Shagufta Andleeb*1, Fariha Zahid1, Noor-ul-Ain1, Yousra Nisar1, Chaman Ara2
...d distilled water. These doses were injected into eggs on 3rd day while recovery of embryos was done on 7th day of incubation. Disrupted embryos with microcephly, hydrocephaly, short neck, micromelia, amelia, micrognathia, agnathia, cataract, ectopiacordis, omphalocoel, axis distortion, anencephaly, anophthalmia, microphthalmia, phocomelia with reduced body weight and crown- rump length in all dose grou...

Imran Khan1, Zahir Shah2, Wiqar Ahmad3*, Farmanullah Khan2 and Muhammad Sharif

...00 kg ha-1), Recommended dose (RD; N:P2O5:K2O=120:90:60 kg ha-1), Farmyard manure (FYM) alone at the rate of 5, 10, 15 and 20 t ha-1 and the integration of 5, 10 and 15 t ha-1 FYM with 75, 50 and 25% of the RD, respectively. Tillage practice included shallow tillage (ST; 0-20 cm) and deep tillage (DT; 0-40 cm). The FYM alone resulted in increased soil NPK, organic matter (OM) and the electrical conductivity (EC) but failed to improve the yield significantly. H...
Muhammad Khalid Mukhtar1,*, Hummaira Iqbal1, Hafiz Muhammad Tahir2, Haseena Ghulam Muhammad1 and Muhammad Irfan1
...y density and sub-lethal doses of two commonly used insecticides i.e., bifenthrin and chlorpyrifos, on the consumption rate of web weaving spider Cyrtophora citricola, was observed. Live spiders for the study were collected from citrus orchards of Sargodha and maintained individually in the laboratory. Both the control and insecticide treated spiders were offered larvae of Drosophila melanogaster in different densities. C. citricola...
Farah Rauf Shakoori1,*, Anum Feroz1, Ayesha Gondal1,Sahar Akram2 and Tanzeela Riaz3
... godowns. The sub lethal dose of λ-cyhalothrin (LC20) significantly increased the contents of free amino acids and soluble proteins while contents of total proteins, lipids, glycogen and trehalose were significantly reduced with reference to their control (untreated group). Among carbohydrate metabolizing enzymes, the activities of amylase and invertase were significantly reduced while activity of trehalase were significantly increased after ...
Mohammed Al Bratty1, Hassan A. Alhazmi1, Somaya Jadoh Ogdi1, Jana Ahmad Otaif1, Abdul Jabbar Al-Rajab2, Mohammad Firoz Alam3 andSadique Akhtar Javed1,*
...espective reference oral doses (RfD) set by USEPA. The non-carcinogenic health risks to the target population due to exposure of the tested metals were assessed by estimating the Hazard Quotient (HQ) and Hazard Index (HI) values. The HQ and HI values observed in this estimation were less than one, suggesting that the exposure of these heavy metals through the consumption of Baladi chicken is unlikely to produce potential health risks to the population of the t...
Muhammad Nazar Aftab1, Ahmed Ali1, Muhammad Asad1, Sadia Fatima2 and Furhan Iqbal2,*
...treatments at the end of dose supplementation. Our results revealed that oral supplementation of 80mg/Kg body weight of AlCl3 for 16 days did not affect (P > 0.05) any of the studied parameters of complete blood count. On the other hand, serological parameters like triglycerides (P = 0.0075 ), total proteins (P = 0.042) and creatinine (P = 0.0038)were significantly higher in treated male mice when compared with their untreated control group indic...

Fayaz Ahmad1*, Noorullah Khan1, Farrukh Siyar Hamid1, Qamar uz Zaman1, Shamsul Islam1, Muhammad Abbas Khan1 and Sair Sarwar

...able time of pruning and doses of potash fertilizer for deep pruning of tea bushes and their subsequent efficient recovery and proper growth. The experiment was laid out in Randomized Complete Block Design with three replications. Mature tea plants (26 year old) of Qi-men variety were deeply pruned (30 cm from the ground level by completely defoliating the bushes) on five different dates i.e., November, December, 2012, January, February and March, 2013 having ...

Wiqar Ahmad1* and Farmanullah Khan

...O), iii. Recommended NPK dose (RD; 120:90:60 N: P2O5: K2O ) and iv. 60:90:60 N: P2O5: K2O integrated with FYM 20 t ha-1 (N1/2PKF) in sub plots. Maize (Zea mays L.) CV Azam (yield data contained in this paper belongs to maize only), wheat (Triticum aestivum L.) CV Uqab and lentils (Lense Culinarus M.) CV NM-89 were cultivated in rotation. Results revealed that during 2006, maize yield did not improve significantly, however, during 2007, grain yield (GY) increas...
Tariq Mukhtar
...ot weight of tomato in a dose dependent manner. Doses of 8×103 and 1×104 cfu/g of soil showed maximum increase in shoot weight and decrease in root weight. On the other hand, both the antagonistic fungi caused significant reductions in number of galls, egg masses, eggs per egg mass and reproductive factors of M. incognita in a dose dependent manner....

Muhammad Fiaz1*, Muhammad Afzal1 and Muhammad Zeeshan Majeed1,2 

...d (FD) and its half (HD) dose rates of spirotetramat and I. fumosorosea formulations. Both treatments were applied either alone or in binary combinations. There was a significant reduction in psyllid population for all treatment combinations as compared to control (F8, 107 = 70.36; P-value = 0.001 for 2016 and F8, 107 = 63.58; P-value < 0.001 for 2017). Combined application of spirotetramat along with I. fumosorosea formulation has shown a significant syner...

Saeed Ullah1, Amanullah Jan1, Murad Ali2*, Wiqar Ahmad3, Hafeez Ur Rehman2, Muhammad Ishaq2 and Bilal Ahmad2  

...nt results even at lower doses emphasizing proper application method as more important than mare increasing nutrient levels for obtaining higher returns 

...

Muhammad Shoaib Saleem*, Muhammad Faheem Akbar, Amjad Sultan and Saqib Ali 

...control. The recommended doses of Nitenpyram, Clothianidin, Momentum (combination of Nitenpyram+Chlorfenapyr) and Buprofezin were applied when population of insect pests reached at economic threshold level (ETL). Pre-treatment data were taken before 24 hours and post-treatment data were recorded after 24, 72, 168 and 336 hours of each spray. In this manner the data of three sprays were collected. Amongst neonicotinoids Clothianidin was found to be very effecti...
Madeeha Arshad1, Asmatullah1, Chaman Ara1, Shagufta Andleeb2 and Naveed Ahmad3,*
...nd 16.66 µg/g B.W. dose groups showed abnormalities such as skin hemorrhages, microphthalmia, limb deformities, hygromas, kyphosis, curved and short tail and fluid filled abdominal cysts. Significant increase in intrauterine growth retardation and resorptions of fetuses, with increasing dose concentration, was also observed. Morphometric observations of fetal body parts like head circumference, eye circumference, forel...
Azmat Hayat Khan Khattak1, Muhammad Nauman ul Islam1, Muhammad Shakir Khan1, Muhammad Iqbal1, Imtiaz Ali Shah1,Sheeraz Ghani1, Amjad Ali2, Zubina Hameed1, Mohammad Farooque Hassan3 and Tariq Ali1,3,*
...ody weight) in two equal doses, one in the morning followed by an evening dose, until the end of 8th week. The average birth weight of AJC was 15.75±2.43 kg; while, it was 28.18±0.87 kg for ABC calves. The average weaning weight was 43.56±4.3 kg and 56.5±2.75 kg for AJC and ABC calves, respectively. Whereas, the average weight gains in AJC and ABC calves was 0.331 kg/d and 0.337 kg/d, r...
Farah Rauf Shakoori1,*, Tanzeela Riaz2, Uzma Ramzan1, Anum Feroz1 and Abdul Rauf Shakoori2,3,*
...ectively. The sub lethal dose of esfenvalerate (LC20) significantly decreased the contents of glycogen, glucose, trehalose and free amino acid while total protein and total lipid contents, were significantly increased with reference to their control (untreated group). Among carbohydrate metabolizing enzymes, the activities of trehalase, amylase and invertase were significantly reduced after treatment with sub lethal dose

Muhammad Sajid Mahmood1*, Muhammad Ashraf1, Ijaz Ahmad2, Muhammad Khubaib Abuzar3, Sohail Latif4 Muhammad Aqeel Sarwar5 and Waqas Ahmad6 

... in combination with low doses of pendimethalin (pre-emergence) for weed control in mungbean during summer season, 2009. The treatments were: Control (weedy check), Hand weeding (30 and 45 DAS), Pendimethalin herbicide @ 1.5 kg a.i. ha-1 (recommended dose), Barley W.E. @ 12 L ha-1 (20, 30, 40 and 50 DAS), Barley W.E. + pendimethalin @ 12 L ha-1 + 1.0 kg a.i. ha-1, Barley W.E. + pendimethalin @ 12 L ha-1 + 0.75 kg a.i. ha-1, ...

Muhammad Zahid1, Naeem Iqbal1, Sohaib Muhammad2*, Summiya Faisal3, Wajid Mahboob3, Makhdoom Hussain4 and Zaheer ud din Khan2 

...ced by exogenous glucose doses in terms of improved growth, yield and physiological traits. 

...
Xiaqing Chen, Yü Huang and Zhen Huang*
...l growth inhibition in a dose-dependent manner was observed when ethyl acetate extract and carbendazim were applied individually. The EC50 of T. hamatum ethylacetate extract or carbendazim in mycelial growth inhibition of S. shiraiana was 6.6 μg/ml or 39.5 μg/ml under laboratory condition, respectiviely. The level of synergism between ethylacetate extract and carbendazim was affected by the concentration of each component in...

Malik Muhammad Yousaf1*, Muhammad Zeshan1,2, Mumtaz Hussain1, Muhammad Mohsin Raza1, Muhammad Jahangir Shah1, Bashir Ahmed1 and Sabir Hussain Shah3 

...lacement timing is split dose of fertilizer at T3 (½ at 1st irrigation and ½ at flowering) for either urea or CAN fertilizer. 

...
Li Lv1, Liuan Li1,*, Ruibo Zhang1, Zhichao Deng1, Tianming Jin1 and Gaimei Du2
...l group), 0.3 mg/kg (low-dose group), 0.6 mg/kg (medium-dose group) and 1.2 mg/kg (high-dose group). Each experimental group had four cohorts and each cohort had 10 hens. Experimental diets were fed for 28 d and daily egg production was recorded. Eggs were collected every seven days for determination of egg white, egg yolk and total egg selenium using hydride generation-atomic fluorescence...
Saleh S. Alhewairini
... the quarter recommended dose (QRD), half recommended dose (HRD) and recommended dose (RD) of oxamyl only and with the recommended dose (RD) of Injo200 or 1000ppm of Huwa-SanTR50, respectively. The percentages of larvae hatching from eggs of O. afrasiaticus were 97.20, 94.62 and 85.53%; 94.70, 93.32 and 84.86%; 54.01, 57.93 and 46.21% after one we...

 *Muhammad Waseem1, Dost Mohammad Baloch1, Ghulam Khaliq1,
M. Rashid1, Qurban Ali2 and Mustajab A. Khan3

INTENSIFICATION IN BAMBOO (Bambusa bambos L.) TRAITS IN RESPONSE TO ORGANIC AND CHEMICAL NITROGEN ALONG THE COAST OF ARABIAN SEA
...om urea (the recommended dose) + 50% N from Farm Yard Manure (FYM)}. A recommended dose of nitrogen was used as chemical source and applied at the rate of 120 kg N ha-1. Significant differences were reported for studied traits in response to treatments. The results indicated that significant correlation was found among the traits such as plant height, number of culms per plant, stem diameter of culms and growth rate of newly...

Tasleem Akhtar, Nadeem Sheikh*

Induction of acute phase in response to tacrolimus induced hepatotoxicity
...4 and 48 h of tacrolimus dose. Densitometric analysis revealed considerable elevated level of some positive acute phase proteins, specifically C-reactive protein, haptoglobin and ceruloplasmin. While albumin and transferrin levels were found to be low as compared to control animals. The results obtained in this study revealed that tacrolimus resulted in the onset of acute phase response in experimental animals owing to its toxic potential.

...

 Shagufta Andleeb*

Teratogenic potential of pyrethroids: a review
...c potential of sublethal doses of different types of pyrethroids in various groups of animals in systematic way. On line available data interpretation through Pubmed Central NCBI, Google Scholar and Google was done to achieve the target and 122 references were found the most relevant in this perspective.

...

 Hafiz Muhammad Tahir1*, Zafar Iqbal Khan2, Saira Batool2, Kafeel Ahmad2, Salma Begum2

Residual effect of lambda-cyhalothrin on abundance of insect pollinators in marigold field patch
...ions. Recommended
dose of lambda-cyhalothrin (0.093gm/ml) was used. The number of different
pollinators that visited the marigold plant before and after insecticidal spray was
recorded. In semi-field experiment, honey bees were exposed to insecticide treated
plants for one hour. The mortality rate of honey bees in the control and insecticide
exposed group was compared. Overall, a significant decline in plant pollinators was

Madeeha Arshad, Asmatullah, Chaman Ara

Embryotoxic effects of sodium arsenate in Mus musculus
...Mus musculus). Different doses of sodium arsenate
18.25, 37.5 and 75mg/kg B.W. were administered orally at day 6 of gestation
(single exposure group) to 15 females/dose group along with one control group
having 15 females, which was given only distilled water. Pups were recovered on
18th day of gestation and fixed for morphometric morphological and histological
analysis. Morphometric observ...

 Khurram Shahzad1*, Muhammad Naeem Khan1, Farhat Jabeen2, Nasreen Kosour3, Muhammad Sohail1, Muhammad Khalil Ahmad Khan1, Munir Ahmad1

Bioaccumulation of manufactured titanium dioxide
...sh were exposed to three doses of
nanoparticles suspensions T0 (no dose administration), T1 (0.5 mg/L), T2 (1.0
mg/L) and T3 (1.5 mg/L) for 14 days. After 14 days, animals were slaughtered and
organs (gills, liver and muscles) were freeze dried. Freeze dried tissue samples
were digested with the help of nitric acid (HNO3) and perchloric acid (HClO4). Acid
digested samples were analyzed by I...
Atiq-ur-Rehman1,2,*, Abida Latif1,*, Rukhsana Anwar1, Nasir Abbas1, Sajid Nawaz2 and Hamid Turab Mirza3
...g/kg and 500 mg/kg b.w.) dose levels were administered to the rats and the samples of blood were taken at 0 h, 0.5 h, 1 h, 2 h and 3 h intervals. In vitro results showed that chloroform fraction at concentration of 100 µg/ml showed maximum α-amylase inhibition (53.11 ± 0.97% with IC50 value of 93.61 ± 4.44 µg/ml) followed by ethyl acetate, n-hexane and n-butanol fractions. The reference standard acarbose (100 µg/ml)...

Muhammad Shahzad Akbar, Muhammad Zeeshan Majeed* and Muhammad Afzal 

...egion. Label-recommended dose rates of insecticides were tested against worker termites using modified filter paper disc method according to completely randomized design. All insecticides caused significant mortality of termites as compared to control treatment. Formulations of chlorantraniliprole, chlorfenapyr and pyriproxyfen exhibited maximum termite mortality, ranging from 31.18±5.67, 28.33±7.03 and 21.67±4.01%, respectively at 3 h pos...
A.M. Abdul Azeem, A.N. El Shahat* and Ashraf M. Mounir
...red by exposure to toxic dose of lead.
...

Misbahullah, Shad Khan Khalil, Asim Muhammad*, Afza Tabassum and Shah Fahad  

..., 2/3 of the recommended dose) and 3 times of application (emergence,tillering,50% at emergence + fifty percent at tillering). Herbicide sole, weeded by hand and un weeded plots used for comparison. Results showing that concentration of sorghum and appliance point considerably increased days to heading, anthesis, physiological maturity, area of flag leaf, tillers number m-2 and spikelets per spike and decreased weed density in wheat. Sorghum extract sprayed at...

Fouzia Tabssum1, Qamar uz Zaman2*, Yinglong Chen3,4, Umair Riaz5*, Waqas Ashraf6, Ambreen Aslam2, Nusrat Ehsan2, Rab Nawaz2, Humera Aziz7 and Shamim ul Sibtain Shah8 

...application of optimized dose of proline both at seedling establishment and vegetative stage significantly improved the performance of rice cultivars by improving tillering dynamics, plant water-relations, chlorophyll pigments, photosynthetic pigments, morphological and yield related traits of rice cultivars. Proline application improved the efficiency of salt tolerance of rice cultivars, Shaheen basmati showed better response in terms of yield than Super basm...
Shaher Bano1, Sarah Ghafoor1,* and Nadia Naseem2
... rats were given T3 at a dose of 1mg/kg body weight. All the animals were sacrificed on 15th day. Weight of each rat was calculated at the time of T3 administration. Body weight of experimental animals increased at a slow rate as compared to the control animals. The immunohistochemical expression of TGF-α in ductal epithelium of both salivary glands was decreased in experimental group sacrificed at 5 weeks. However no significant change was ob...
Radek Aulicky1,*, Vaclav Stejskal1 and George Opit2
...posure of strips or high dose DDVP aerosols for T. castaneum, C. ferrugineus, R. dominica and S. granarius.
...
Ghulam Ali1,3, Wopke van der Werf2 and Just M. Vlak1,
...application of two viral doses of Spodoptera litura nucleopolyhedrovirus (Pakistan isolate SpltNPV-Pak-BNG). Infected larvae with final polyhedrosis (disease resulting in dissolution of larval tissues and accumulation of viral occlusion bodies) exhibited reduced food intake and weight gain relative to uninfected larvae. The unexposed larvae and the larvae that were exposed but survived exhibited the same food consumption and weight gain. This study did thus no...

Masaud Khan1*, Muhammad Jamal Khan1, Tahir Sarwar1 and Muhammad Jamal Khan2 

...along with four Nitrogen doses i.e. 100% of recommended dose (120kg) (N100), 85% of recommended dose (N85), 70% of recommended dose (N70) and 55% of recommended dose (N55). Frequency Domain Reflectometry (FDR) was used for soil moisture monitoring. Full irrigation was determined on the basis of MAD 30%. Simulation of n...
Muhammad Asad Saleem1,*, Mirza Abdul Qayyum1, Mudssar Ali1, Muhammad Amin2, Muhammad Tayyab1,3 and Sumaira Maqsood4
...vival against sub-lethal doses of B. bassiana and biorational insecticide (Nitenpyram). Sugarcane sets as alternate to date palm stem were successfully used as diet for rearing RPW. Combination of entomopathogenic fungus (Bb) and Nitenpyram (Nit) were found more lethal to survival of RPW. A reduction in pupation and adult emergence was recorded in the combined treatments. Moreover, decrease in weight gain, frass production and cumulative gain in size wa...
Aqeel Mehboob, Syed Muhammad Zaka*, Muhammad Sarmadand Maryam Bajwa
...pests at the recommended doses of synthetic pesticides, alternative methods like botanical extract in the control of this pest consider greater importance nowadays. The antifeedant and oviposition deterrent index of Moringa oleifera, Murraya paniculata and Piper nigrum leaf extracts were evaluated against S. litura by choice and no choice method under laboratory controlled conditions. In M. oleifera extract, the maximum antif...

Muhammad Naveed Afzal1, Muhammad Tariq1*, Muhammad Ahmad1, Khuram Mubeen2, Muhammad Ayaz Khan3, Muhamamd Umer Afzal4 and Shakeel Ahmad

...FP) was maximum with low doses of nitrogen. Whereas, the percent relative yield (PRY) at 50 kg N was very low in relevance to 150 kg. 

...

Ali Awais, Charassri Nualsri and Watcharin Soonsuwon* 

...nvestigate the effective doses of EMS and to observe the phenotypic variability of the two upland rice genotypes Dawk Pa-yawm (white rice) and Dawk Kha 50 (red rice), in Thailand. Seeds of the potential genotypes has been treated with varying EMS concentrations. With the increase in concentration, there was a continuous decrease in germination, shoot and root lengths respectively. Data have been subjected to regression analysis and effective
Temel Göktürk1,* and Göksel Tozlu2
...er larvae. Different doses of Pyrethrum and Bacillus thuringiensis biopesticides (Spruzit® Neu from 150ml to 600ml/100 l, and DiPel® DF BT 100 to 500 g/100 l) were applied against the larvae of D. pini and N. sertifer their impact was monitored under laboratory conditions. The finding of the study revealed that the most effective dosages for larvae of D. pini was Dipel 300 g/100 l and Dipel 500 g/10...

 Attaur Rahman1, Sadeeq ur Rahman1,*, Ashfaq Ahmad2, Abdul Sajid1, Muhammad Asif Hussain1, Mian Muhammad Salman1, Niamat Ullah Khan1, Kamran Khan3, Fazli Rabbani1, Muhammad Akbar Shahid4, Irshad Ahmad5 and Shakoor Ahmad6

.../ml/bird (chicken lethal dose 50 (CLD50)) was injected to ostriches and broiler (control) and were clinically observed for 7 days. Our results showed that a peak cloacal temperature was recorded on day 3 and day 4 with a 2.3°F and 1.2°F maximum rise in broiler and ostrich, respectively. A decrease in feed and water intake was recorded in both broiler and ostrich from 116 g to 82 g/bird and from 235 ml to 172 ml/bird for broiler, and from 130...

 Mahroze Fatima1*, Muhammad Afzal2 and Syed Zakir Hussain Shah3

...e effect of dietary high doses of vitamin E on Labeo rohita fingerlings. Five experimental diets were formulated to contain one control (VE0), two adequate levels of vitamin E supplementation, i.e. 100 and 150 mg/kg diet (VE100, VE150) and two high levels of vitamin E supplementation, i.e. 1000 and 1500 mg/kg diet (VE1000, VE1500). At the onset of feeding trial, 375 fish of nearly unif...
Muhammad Shahid Nadeem*, Maryam A. Al-Ghamdi and Jalaluddin Azam Khan
...rcinoma cells (HepG2). A dose of 5U/ml of enzyme has shown an anti-proliferative effect up to 65 percent on HepG2 cells.
...
Rıfat Ertekin1*, Mete Ozkurt1, Gokhan Kus2 and Selda Kabadere1
...0, 25, 50, and 100 μM doses of TA were applied to T-98G and LNCaP cell lines for periods of 24 and 48 h. Subsequent cell vitality was tested with MTT Atest. The effective doses were analysed by flow cytometry and real-time PCR techniques. MTT spectrophotometric tests showed no significant effects on the survival rate of T-98G cells in 24 and 48 h. Therefore, T-98G cells were not analysed by flow cytometry and RT-PCR. When...
Sheng Niu1, Ali-Raza Jahejo1, Fa-jie Jia1, Xin Li1, Guan-bao Ning1, Ding Zhang1, Hai-li Ma1, Wei-fang Hao2, Wen-wei Gao1, Yu-jun Zhao1, Shi-min Gao1, Jian-hui Li1, Gui-lan Li1, Fang Yan1, Rong-kun Gao1, Huan-chun Chen1,3 and Wen-xia Tian1,*
... injected with different doses of recombinant glutathione-S-transferase A3 (rGSTA3) proteins. We explored the responses of HDPs in erythrocytes to thiram-induced TD and rGSTA3 protein by quantitative real time PCR (qRT-PCR). The results showed many HDPs expressions were suppressed by thiram-induced TD, and the expressions of HDPs were upregulated by rGSTA3 protein. These findings demonstrated that mRNA expressions of HDPs are highly related to thiram-induced T...

Zafar Abbas1*, Muhammad Mubashir1, Umair Riaz1, Zeenat Javid1, Muhammad Ashraf1, Saeed ur Rehman1, Muhammad Javid Qamar1, Syed Ali Zulqadar1 and Shahzada Munawar Mehdi2 

...o compost), T2 (NPK full dose @ 150 kg ha-1N, 75 kg ha-1P and 60 kg ha-1K), T3 (full dose of poultry manure (PM) @ 30 ton ha-1), T4 (50% NPK+50% Poultry Manure i.e. 75 kg ha-1N, 37.5 kg ha-1P and 30 kg ha-1K +15 ton ha-1 PM), T5 (full dose compost @ 30 ton ha-1), T6 (50% NPK+ 50% compost i.e. 75 kg ha-1N, 37.5 kg ha-1P and 30 kg ha-1K + 15 ton ha-1 compost). Plants growth and yield paramet...

Munazza Yousra1*, Sair Sarwar1, Muhammad Mahmood Ul Hassan1, Muhammad Zameer khan1, Abdul khaliq2, Shahbaz Ahmad1 and Shamim Ul Sibtain Shah3 

...n with the increasing Zn doses in both varieties. The maximum Zn concentration recorded was 67.6 and 79.5 mg kg-1 @ 8 mg Zn kg-1 by using both Zn sources, respectively. The highest dry matter production of 65 and 76 g plant-1 was recorded using Zn treatment @ 8 mg Zn kg-1 by ZnSO4.H2O and Zn-EDTA in both varieties, respectively. Similarly, the Zn uptake was also shown significant increase over control at the Zn rate applied @ 8 mg kg-1 with ZnSO4.H2O (3.97) an...
Kun Wang1,2, Yinglin Cui2, Xu Zhao2 and Changjiang Hu1*
...e nucleus. XN (at a high dose and a low dose of 3.60g·kg-1 and 1.80g·kg-1, respectively) was administered via enema. The detection of neuronal apoptosis was measured by TUNEL assay. Using immunofluorescence, the expression of claudin-5, ZO-1 and VE-cadherin was detected. The expression of DNA methyltransferase 3b (DNMT3b) and Matrix metalloproteinase-9 (MMP-9) was evaluated by western blot...
Nouf Alharbi*, Mai Elobeid and Promy Virk
.../d) and treated with low dose of quercetin (50 mg/kg bw/d), Group IV orally administrated cadmium chloride (5mg/kg bw/d) and treated with high dose of quercetin (70 mg/kg bw/d). Experimental period was four weeks. The protective efficacy of quercetin was evaluated in terms of cadmium (Cd) accumulation in liver and hair, blood profile, catalase (CAT) and superoxide dismutase (SOD) activity in liver, malondialdehyde (MDA) leve...

 Aftab Khan1, Shahid Ali1, Murtaza1, Sufyan Ullah Khan2 and Syed Attaullah Shah1

...ropriate and recommended dose of these inputs. Allocative efficiencies of tractor hours, FYM and labour were 1.16, 1.02 and 0.97, respectively, suggesting that these inputs were efficiently utilized. Facilitation of maize growers with subsidized and timely availability of inputs, provision of agriculture credit with reasonable interest rate and easy instalments and field based trainings are policy options for enhancing maize productivity. 

...
Saleh S. Alhewairini
...ation of the recommended dose, the adult mortality percentages were 66.67, 73.33 and 100% for acetamiprid and 23.33, 60 and 96.67% for sulfoxaflor after 1, 24, and 48 h, respectively, whereas the larvae mortality percentages were 63.33, 73.33 and 100% for acetamiprid and 46.67, 73.33 and 96.67% for sulfoxaflor after 1, 24, and 48 h, respectively. Moreover, live RPW (larvae and adult) were found to be completely paralyzed after 24 h of exposure to both insectic...
Muhammad Aslam Farooqi*, Bakhtawar Irsa, Sajjad Ali, Asif Sajjad, Muhammad Waqar Hassan and Sohail Akhtar

 

... their recommended field doses. Mortality of A. mellifera was recorded at 0.5, 3, 6 and 24 hours after exposure to insecticides. To evaluate the toxic impact, median lethal concentration (LC50) of each tested insecticide was determined. The results obtained, revealed that all insecticides were highly toxic after 24 hours of exposure at maximum concentration. Acephate and lymda-cyhalothrin showed the maximum toxicity with their LC50
Muhammad Usman Akhtar1,2, Abdul Qayum3, Anshan Shan1,*, Shuli Chou1, Hyeonsoo Jo4, Syed Waqas Ali Shah4 and Ishfaq Muhammad5
...iet has a linear effect (dose-dependently) on nutrient digestibilites, nutrient intake and milk yield. Dry matter (DM), crude protein (CP), neutral detergent fiber (NDF) and acid detergent fiber (ADF) intake were higher (P < 0.05) in goats fed 70RDP diet than those fed 30RDP diet. Nutrients digestibilities (DM, CP, NDF and ADF) were significantly higher (P < 0.05) in goats fed 60RDP diet than those fed 30RDP. Goats fed 70RDP diet produced higher milk yie...
Shad Mahfuz1,2, Shuyuan Wang1, Mo Chen1, Fei Zao1, Dong Zhen1
Zhongjun Liu4 and Hui Song1,3*
...eliminate the use of low-dose antibiotics in poultry production. Therefore, the aim of this study was to examine the effectiveness of Flammulina velutipes stem waste (FVW) inclusion in laying hens diet on production performance, egg quality and serum metabolic profile during the early phase of production.A total of 105 ISA Brown 18 wk old laying hens were grouped into 5 treatments with 7 replications of 3 hens each. Dietary treatments included a basal d...
Muhammad Izhar Shafi* and Muhammad Sharif
...plication of recommended dose of DAP with HA can be the optimal source for the improvement of P availability and mineralization in given soil conditions.
...
Shagufta Naz1, Ayesha Javed1, Ayesha Saleem1, Khadija Murtaza1, Rukhama Haq1, Akbar Hayat2 and Neelma Munir1,*
...ted with three different doses of gamma radiation such as 0.5, 1 and 2 kGy. Effects of gamma radiation were analyzed for different aspects like microflora, moisture, fat, ash, fiber, phenolic content, sprouting inhibition, physiological weight loss, pyruvate analysis and sugar contents. Gamma radiation affected these parameters at higher doses but at 0.5 kGy no significant change was observed. 0.5 kGy prouting was inhibited ...
Wiqar Ahmad1*, Farmanullah Khan2, Muhammad Sharif2 and Muhammad Jamal Khan2
...nd lentils), recommended dose (RD) (N:P2O5:K2O @ 120:90:60 and 30:60:0 kg ha-1 for cereal and lentils) and integrated nutrient management (INM) (N:P2O5:K2O + FYM @ 60:90:60 kg + 20 t ha-1 for cereals and 7:30:0 kg + 20 tons ha-1 for lentils) were applied in sub-plots (20 m2) of an RCB design. In INM, significant (p<0.05) improvement in wheat and len...

Muhammad Shahzad Akbar*, Maria Aslam, Muhammad Rehan Khalid, Shahid Iqbal, Muhammad Luqman and Muhammad Zeeshan Majeed 

...each treatment using log-dose probit analysis. Results revealed a mortality response of termites directly proportional to the extract concentration for all treatments. The floral extracts of basil (O. basilicum) and Tecoma (T. stans) exhibited maximum termite mortality (i.e. 55.5 and 50.0%, respectively) with minimum LC50 and LT50 values, followed by the extracts of chrysanthemum (G. segetum) and African marigold (T. erecta). Overall study results suggest that...

Matiullah Khan1*, Motsim Billah2, Shoaib Ahmad1, Raza Ullah Khan1 and Muhammad Sarwar1 

...h three repeats. Various doses of PEC (6, 4, 2 Mg ha-1) were compared with simple poultry-litter compost (PLC) as 8 Mg ha-1, single super phosphate (SSP) fertilizer as 100 kg P2O5 ha-1 and control. The results showed that PEC at 6 Mg ha-1gave 14.7% and 7.7% increased paddy yield and 14.7% and 11.9%-increased total dry matter yield over PLC at 8 Mg ha-1 and SSP, respectively. The highest soil post-harvest extractable P content of 5.42 mg kg-1and rice-plant P up...
Muhammad Furqan Shahid1*, Tahir Yaqub1, Muhammad Yasin Tipu2, Asim Aslam2, Saima Yaqub1, Aziz-ul-Rahman3, Muzaffar Ali1
...ed experimentally at the dose of 106 EID50 by using these three isolates. Results revealed that onset of clinical signs was started at 2nd day post infection (DPI) followed by severity in redness and swelling of eyes, sneezing and lacrimation at 3rd DPI that lasts up to 5th DPI. Cross reactivity of antiserum response toH9N2 was compared among reference isolates when challenged in broilers, Partridge origin...
Naila Riaz1, Hafiz Muhammad Tahir2, Muhammad Khalid Mukhtar1, Ali Hassan2, Shaukat Ali2, Shafaat Yar Khan1
...54kDa, respectively. The doses of venom fractions used during the study ranged from 10-30µg/ml. Both venom fractions significantly inhibited the activity of AChE. However, 30µg/ml dose of both scorpion venom caused 100% mortality in adult M. domestica. . It was concluded that the venom of scorpions contains peptides fractions that may be used as potential bio-pesticides.

 

...
Haq Aman Ullah1,*, Aneela Zameer Durrani2, Muhammad Ijaz2, Aqeel Javeed3, Muqadder Shah1 and Ikramul Haq1
...igate the effects of low doses of dietary aflatoxin B1 (AFB1) on physiological biomarkers with special reference to udder health and serum parameters of lactating goats. Thirty two lactating Beetal goats of 3-4 y age, weighing 40.91±0.285, were randomly selected, and equally divided into four groups. Group A was kept as control while animals of groups B, C, and D were individually fed daily with 30µg, 40µg and 50µg of AFB1, respectivel...
Chaman Ara1*, Asmatullah1, Sehrish Kanwa1, Asma Chaudhary2, Ayesha Siddiqua1
...day (24 hours after last dose administered) under deep chloroform anaesthesia. Blood was extracted through cardiac puncture and viscera were dissected out for further analysis. Levofloxacin induced reduction in body weight while caused a noticeable increase in liver, kidney and testis weights. Significant increase in levels of total alkaline aminotransferase (ALT), aspartate transaminase (AST), alkaline phosphatase (ALP) and bilirubin was observed in blood pla...
Chaman Ara1*, Asmatullah1, Zainab Riaz1, Memoona1, Asma Chaudhary2, Shagufta Andleeb2
...ve groups, i.e. Control, dose group (BP), dose and antidote group (BP+AD), vehicle control group (VC) and antidote group (AD). A sub lethal concentration containing 15ug/g B.W of BP was given with and without turmeric orally, dissolved in corn oil, used as vehicle too. Dissections were made on 31st day, twenty-four hours after the last dose administration. Results showed that co...
Fariha Latif1*, Muhammad Javed2, Hammad Ahmad Khan2 and Khalil-Ur-Rehman3
...s to assess the time and dose dependent effects of Pb on bioaccumulation and oxidative stress in the liver, kidney, gills, muscles and brain of Cirrhina mrigala. The 120-days old fish were exposed to 1/4th (11.81mgL-1) and 2/3rd (31.49mgL-1) of 96-h LC50 of water-borne Pb for three fortnights (42 days) in glass aquaria at pH 7.5, temperature 30°C and total hardness 250mgL-1. After eac...
Saman Muhsin Abdulkareem* and Nadir Mustafa Nanakali
...ally administered at the dose of 10µg/kg /day and 20 mg/kg/day, respectively by gavage dissolved in corn oil for 90 days. At the end of the study, animals were sacrificed and their liver were removed for biochemical analysis including the level of oxidative stress biomarkers, liver enzymes, and the expression of CYP1A1 gene. The results of this study indicated that exposure to TCDD (10µg/kg/day) could significantly increase liver oxidative s...
Mubasher Ahmad Malik1, Samina Jam Nazeer Ahmad2, Muhammad Jalal Arif1 and Jam Nazeer Ahmad1,*
.../sub>and LC50 dose rates. The combination of 349.3 parts per million of AZA and 4.8×104 occlusion bodies per millimeter of PxGV, resulted in synergistic interaction after 3rd, 5th and 8th days post application while the additive effect was observed only after 1 day post-treatment. Moreover, combined application of PxGV and AZA at sub-lethal doses exhibited increase...

Jawad Ali*, Ibad Ullah Jan and Hidayat Ullah 

...severe stress)) and four doses of Se (0, 1, 2, and 3 mg L−1) were imposed after 30 days of sowing. Our outcomes showed that drought stress decreases the number of leaves, plant height, number of branches, stem dry weight, root dry weight, fruit diameter, number of fruit per plant and 1000 seed weight. Visually reduction in vegetative and yield parametric quality okra plant okra were significantly alleviated by the foliar application of Se under drought s...
Kadry A. El-Bakry1, Lamiaa E.M. Deef1*, Lotfy Z. Habbak1 and Samia S. El-Naeli2
...ted with PAT in a single dose (3.75mg/kg body weight). Rats were treated with ginger in a dose (100 mg/kg-1 body weight) for 4 weeks and 8 weeks. Blood samples for biochemical analysis and liver tissues were collected and fixed in 10% formalin for histopathological studies. The present study showed that, PAT causes elevated alanine aminotransferase (ALT) and aspartate aminotransferase (AST) activities and significantly incre...

Muhammad Qaisar Nawaz*, Khalil Ahmed, Ghulam Qadir, Muhammad Rizwan, Muhammad Faisal Nawaz and Muhammad Sarfraz 

...e main plot and nitrogen doses (40, 60, 80 and 100 kg ha-1) as sub plot. Treatments were replicated three times with sub plot size of 4 m × 6 m. Measurements included were: number of plant/m-2, number of leaves/plants, root length, bulb diameter, forage yield and total bulb yield. Results revealed that all the studied parameters were significantly improved with nitrogen application @ 80 and 100 kg ha-1 in ridge sowing. However, 80 kg N ha-1 in ridge sowi...
Tanveer Ahmad1, Tariq Mehmood1, Muhammad Shahid1, Adnan Ahmad1,2, Muhammad Asim Raza Basra1, Muhammad Zia-ur-Rehman3* and Munawar Ali Munawar1
... Dawley (SD) rats at the dose of 20mg/kg using glibenclamide (GC). Among these synthesized pharmacophores, six compounds exhibited percentage reduction (20.47±2.54 to 44.97±2.16 %) and (20.79±1.55 to 37±2.94 %) in blood glucose level at 20mg/kg dose compared to glibenclamide (74±3.10 % reduction) 50mg/kg dose of glibenclamide after 2 and 5 hours of oral a...
Jam Nazeer Ahmad1,2*, Rashid Mushtaq1, Samina Jam Nazeer Ahmad1,2*Mubasher Ahmad Malik1, Mujahid Manzoor1, Muhammad Tahir2,  Zubair Aslam4, Sumaira Maqsood5, Ishita Ahuja3 and Atle M. Bones3
...fect of three sub-lethal dose rates (2 x 103, 4.5 x 103, and 6 x 103 PIB/Larva) of native isolated Nucleopolyhydrovirus (NPV) from Spodoptera litura and Spinosad (0.01 ppm) against 3rd and 4th instar larvae collected from three different geographical areas of Punjab (Pakistan). A difference in larval mortality, pupation, adult emergence and egg ecluson was observed. The higher but sub-lethal
Hong-mei Gao, Wen-long Su, Gui-bin Tao, Han-yang Li, Wen-zheng Cao and Zhi-dong Qiu*
...bloosd tissue after high dose irradiation.We found that geniposide can recovery the red blood count after chemotherapy medications (5-Fluorouracil, 5-FU) treatment mice. The mechanism of action of genistein on erythrocyte production is not clear. This study suggests that Geniposide promotes red blood cell production. We demonstrated that genistein did not affect the erythrocyte differentiation of mouse CD34+ cells. Then, we tested the geniposide ind...
Mingsan Miao*, Hui Zhao, Jiaojiao Jia, Xiaoyan Fang and Yanyan Miao
...essfully replicated. The doses of total phenolic acid of D. canes have significantly reduced the levels of IL-6 and TNF-α in brain tissue and decreased the level of NSE in the serum.Collectively, it was observed that the total phenolic acid can protect the brain tissue by inhibiting the expression of inflammatory factors, repairing damaged nerve cells and improving the pathological changes of cerebral ischemia, proposing its therapeutic potential in trea...

Masaud Khan1*, Muhammad Jamal Khan1, Shahab Ahmad2, Asad Ali3, Numan Khan3 and Muhammad Adnan Fahad

...(I45); and four nitrogen doses;100% of recommended dose (120 kg ha-1) (N100), 85% of recommended dose (N85), 70% of recommended dose (N70) and 55% of recommended dose (N55). Io was based on 30% of management allowed deficit. Effect of Nitrogen doses on Nitrogen use efficiency (NUE) w...
Rafia Sadaf1, Ishrat Younus2*, Sidra Maqbool2, Talha Bin Fayyaz3Sarah Jameel Khan1, Sidra Siddique1 and Rida Fatima1
...in rats at two different doses i.e. 250 and 500 mg/kg, and significant anxiolytic effects were observed as compare to control.
...
Saeed Murtaza1, Abdul Sattar1*, Nasim Ahmad1, Muhammad Ijaz2Maqsood Akhtar3 and Muhammad Shahzad4
...trol; n=8), group-2 (Low dose 10IU; n=8) and group-3 (High dose 30IU; n=9) while one animal excluded at milk sampling from group-3 due to unavoidable circumstances. Oxytocin was administered to each buffalo twice daily @10IU and 30IU into group-2 and group-3 respectively, whereas, saline into group-1 within one week of post calving for 48 days. Ultrasonography was performed twice a week to monitor involution changes while mi...
Jiao Qin,Qian-Qian Su and Quan-Sheng Liu* 
...the effects of different doses of cabergoline on the inter- and intra-sexual social behavior and reproduction physiology in adult female lesser rice-field rats, Rattus losea. Results showed that the ovary weight of female rats treated with cabergoline significantly increased at day 24, but there were no notable changes in the uteri regardless dosage and time. PRL in female rats treated by 50 µg/kg cabergoline significantly was decreased by 56% at ...
Meriem Msaad Guerfali1,*, Heitham Hamden1, Salma Fadhl1, Wafa Djobbi1, Lotfi Sillini1, Wafa Marzouki1 and Mohammed Ammar2
...died and showed that for doses up to LC50, annoying effects begin to appear in glial and neurosecretory cells. The LC50 for malathion was 75.61 ppm for the populations treated more than 6 times. Low levels of resistance are suspected and should be confirmed by molecular analyses for malathion. On th...

Hamza Rehman*, Nida Ahmad Khan, Asad Ali, Warda Batool and Kanwal Razzaq 

... 72 hours. Mortality was dose and exposure dependent. Results demonstrated that thiamethoxam was more lethal as compared to imidacloprid for concern insects. 

...

Noor-us-Sabah1*, Mukkram Ali Tahir1, Ghulam Sarwar1 and Sher Muhammad

...ecommended NPK, T3- full dose of FYM, T4- full dose of press mud, T5- full dose of compost, T6- full dose of poultry manure, T7- full dose of sesbania green manure, T8- T2 + ½ FYM, T9- T2 + ½ press mud, T10- T2 + ½ compost, T11- T2 + ½ poultry manure, T12- T2 + ½ sesbania green manure...
Qaisra Siddique1, Sajid Abdullah1, Huma Naz2*, Khalid Abbas1, Laiba Shafique3

 

.../i>kept under sub-lethal dose (4.13 µgL-1) of chlorpyrifos. Fish was kept under chlorpyrifos stress for two months and samples were collected on weekly basis. It was noted that GST level varied significantly with duration. The GST level was raised in first 28 days after that it was dropped off up to 56-day. The trend of GST in fish tissues was observed as muscle<heart<brain<kidney<gills< liver. However, TPCs in selected tissues ...

Tahira Moeen Khan*, Irum Riaz, Shahida Hameed and Bushra Khan 

...50 rpm, pH= 5, adsorbent dose= 0.1 g). While 85% removal efficiency was observed for Raw date seed husk RDS (time= 45mins, agitation speed=250 rpm, pH= 4 and adsorbent dose= 0.5 g). The adsorption isotherms (Freundlich and Langmuir) and adsorption dynamic kinetic studies were also conducted. The comparison between the FTIR, EDX and SEM of RDS and LMDS revealed that with lemon juice microwave activation of adsorbent there w...

Ahmad-Ur-Rahman Saljoqi1, Muhammad Zubair Khan1, Ayesha Bibi2, Muhammad Shehzad Khan1*, Bashir Ahmad

... the effect of different doses of boron, plant extracts and a bactericide in different combinations on tomato plants. This research study was performed at Agricultural Research Institute, Tarnab, Peshawar-Pakistan. Different biochemical tests were conducted to confirm stem rot pathogen. Boron was applied at the rates of 1.97, 2.96 and 3.95 g seedbed-1. Plant extracts were neem (Azadirachta indica) and ghwaraskay (Dodonaea viscosa). Morphological traits such as...

Bilal Atta1*, Muhammad Rizwan1, Arshed Makhdoom Sabir1, Muhammad Dildar Gogi2, Muhammad Sabar1, Bakhtawar3, Faizan Ali3 and Mehran Sarwar

...staneum increased as the dose rate of crude plant extracts and exposure interval increased. The maximum mortality (86.67%) was achieved with the highest dose of crude extract of Z. officinale (80mg per 7.5g wheat) at 10 days exposure interval. Similarly, the highest dose of Z. officinale extract (80ml) was responsible to cause 100% repellency at 2 hours exposure interval. Results also sugg...

Faisal Hafeez, Asad Aslam*, Ayesha Iftikhar, Afifa Naeem, Muhammad Faheem Akhtar and Muhammad Jawad Saleem 

...ict at recommended field doses. The treatments were applied on cotton crop when the jassid population was above ETL level. The most effective insecticide found was Nitenpyram, having minimum population per leaf (0.35, 0.23 and 0.31 in 2018 and 0.53, 0.33 and 0.42 in 2019 after 1, 3 and 7 days of spray), followed by Chlorfenpyr both years. However, Acephate was ineffective to control jassid population. Moreover, the order of percentage population change/reducti...
Alicja Kowalczyk1, Marian Kuczaj2, Anna Szul3 and Ewa Czerniawska-Piątkowska4*
...acturers of insemination doses to improve the quality of their product.
...
Imran Khan1, Muhammad Nawaz1,*, Aftab Ahmad Anjum1, Mansur-ud-Din Ahmad2, Adnan Mehmood1, Masood Rabbani1, Amina Mustafa1 and Muhammad Asad Ali1
...challenged with a single dose of 106 cfu of Salmonella enteritidis by oral gavage. D-xylose absorption capacity and gut morphometric parameters (villus height, crypt depth and villus height to crypt depth ratio) were studied at day 35. Broiler administered with IKP23, IKP111 and IKP333 significantly improved villus height and villus height to crypt depth ratio as compared to positive control. D-xylose absorption was also enhanced in groups ad...
Muhammad Saeed Imran1, Asim Aslam1*, Muhammad Yasin2, Tahir Yaqoob2 and Beenish Zahid3
...3 EID50 dose of NDV and IBV, respectively. The hosts were divided into six groups of 35 birds each. These were groups A (NDV-challenged), B (IBV- challenged), C (NDV+IBV-challenged), D (IBV+NDV challenged), E (NDV and IBV- challenged) and F (negative control). Mild to moderate clinical presentations were observed in most of the co-infected birds of groups C, D and E. Tissue samples collected at 2nd, 4th and 6th...
Sara Zafar* and Asmatullah
...mice by gavage. The high dose contains Atenolol 2.5 µg/g body weight (B.wt.) of treated mice and low dose contains 1.65 µg/g B.wt. The dose was administered from the 6th -12th day of the gestation period for seven days. Many congenital abnormalities including hemorrhages, hygromas, resorbed fetuses, deformed, hyperextended and hyperactive flexed limbs, distorted axis, and intra...
Dil Afroza Khanom1, Amirun Nesa1, Muhammad Abu Sayed Jewel1, Muhammad Ayenuddin Haque1, Alok Kumar Paul1, Sonia Iqbal2, Usman Atique2,3*, Lubna Alam4
... estimated average daily dose (ADD) intake remained below the reference dose as recognized by the international guidelines of WHO, FAO, and USEPA. Furthermore, the hazard quotient (HQ) and hazard index (HI) outcomes labelled a non-carcinogenic threat to the consumers. In conclusion, this study provides useful insights into the identification of potential risks of these commercially valuable fishes to the continuous consumpti...

Abid Khan*, Mukhtar Alam and Yousaf Jamal 

...NS1 (control), NS2 (full dose from Urea), NS3 (full dose from FYM), NS4 (full dose from PM), NS5 (half dose from Urea + half dose from FYM), NS6 (half dose from urea + half dose from PM) and NS7 (half dose from F...

Ayesha Zafar1, Ghulam Sarwar1*, Muhammad Sarfraz2, Muhammad Zeeshan Manzoor1, Sher Muhammad3 and Ghulam Murtaza

...150% (T5) of recommended dose (150-150-75 kg ha-1) of NPK fertilizer). The experimental design was RCBD with three replications. Intercultural operations were performed according to the experimental requirement. At maturity data regarding plant height, capsules/plant and seeds/capsules, 1000 grain weight, number of plants/m length, grain yield, total biomass and harvest index were recorded. All the above parameters were enhanced by increasing fertilizer rate a...

Wajiha Anum1*, Liaquat Ali1, Umair Riaz2*, Abid Ali1, Nadia Manzoor3, Laal Hussain Akhter4, Asad Ur Rahman5, Naeem Maan6 and Ijaz Ahmad

Muhammad Usman Asif1*, Sadam Hussain Soomro2, Raza Muhammad1, Sikandar Ali Soomro2
...ow, recommended and high doses by leaf dip method. The results concluded that significantly high toxicity was shown after treatment with Neomed 3 SC which caused 100 % to the insect at its recommended (200 ml) and high dose (400 ml) after 24 hours of application followed by Voliam Flexi 300 SC causing 66.66 % and 75% mortality on its recommended (80 ml) and high dose (160 ml), respectively...

Shafiullah1*, Mohammad Nafees2 

MUNICIPAL WASTEWATER TREATMENT BY COAGULATION/ FLOCCULATION PROCESSES VIA OPTIMIZATION OF INOCULATION DOSE AND SETTLING TIME
...en by applying different doses of ferric chloride in
combination of calcium hydroxide. Effective removals of pollutants were obtained by using ferric chloride and calcium
hydroxide in ratio of 2:0.5 mL for settling time of 13 minutes. As treatment results, not only removed suspended
solids (86%) but a tremendous decrease was observed in color, chemical oxygen demand (COD) and turbidity by
96%, 66% and 89%, respectively.

...

 Muhammad Nafees*, Asim Nawab*, Wisal Shah**

STUDY ON THE PERFORMANCE OF WASTEWATER TREATMENT PLANT DESIGNED FOR INDUSTRIAL EFFLUENTS
...ere applied. The optimum doses identified were 25, 35 and 26:13 ml respectively. The settling time was 25, 35 and
20 minutes respectively for lime, alum and alum+lime. The results revealed that the combine treatment (Alum +
Lime) effectively removed suspended load up to 90%, along with 82% BOD, and 80% COD respectively. Therefore,
it was concluded that the installed small scale treatment plant is not enough in its present fo...

M. Rizwan Gul*

COMPARISON OF THE OF MECHANICAL AND WEAR BEHAVIOURS OF DIFFERNT TYPES OF POLYETHYLENES AND THE EFFECT OF RADIATION CROSS-LINKING ON THESE BEHAVIOURS
...ss-linking and radiation dose on these properties. Three different types of polyethylenes: low density (LDPE), high density (HDPE), and ultra-high molecular weight (UHMWPE) were studied. Cross-linking was carried out by high energy electron beam at room temperature, with radiation dose ranging from 0-600 kGy. The results show that the stress-strain curve of UHMWPE in unirradiated state is marked by extensive strain hardening...

Saba Iqbal1*, Muhammad Luqman1, Hafiz Muhammad Nasrullah1, Asmat Ullah1 and Hafiz Muhammad Akram2

Response of Cotton to Application of Organic and Inorganic Source of Nutrients in Semi-Arid Climate
... (recommended fertilizer dose 145-56-62 NPK kg ha-1); T2= poultry manure (8 t ha-1); T3= FYM (10 t ha-1); T4= slurry (10 t ha-1); T5= urea 30 kg ha-1+ poultry manure 6 t ha-1, T6= urea 30 kg ha-1+ FYM 8 t ha-1; T7= urea 30 kg ha-1+ slurry 8 t ha-1; T8= urea 60 kg ha-1+ poultry manure 3 t ha-1; T9= urea 60 kg ha-1+ FYM 4 t ha-1; T10=urea 60 kg ha-1+ slurry 4 t ha-1 . Treatments were laid out in field according to randomized complete block design with three repl...

Olga Mikhailovna Blinnikova1*, Vadim Anatolyevich Babushkin1, Lyudmila Gennadievna Eliseeva2 and Galina Severyanovna Usova3

Modeling a Formulation and Assessment of the Consumer Properties of the Special Purpose Starch Drink
... in the kissel of a high dose of data vitamins of natural origin. P-active connections enhance biological effect of vitamin C, and the high content of ascorbic acid in turn collagen. The designed fruit drinking kissel is the source of food fibers, macro and minerals.

...

Syeda Farzana Bibi* and Siraj-ud-Din

Fluorescence Analysis, Extractive Values and Cytotoxic Screening of Crataeva adansonii DC Leaf and Bark through Brine Shrimp Larvae Assay
...crude drugs of each part dose-dependently exhibited cytotoxic activity. At higher concentration (100-1000 μg/ml) the leaf and bark ethanolic extracts showed cytotoxicity and at lower concentration (10 μg/ml) very low cytotoxic effect was observed (Figure 4). The LC50 values for crude leaf extract were found to be 5.34 and for that of stem bark extract, it was 7.44 ug/ml. This study manifests that the selected plant can be helpful in t...
Gregory Ejikeme Odo1,*, Juliana Ekenma Agwu1, Nkechi Nweze2, Clara Ikegbunam2,Felicia Ekeh N1, Vincent Ejere1, Ngozi Ezenwaji1, Reginald Njokuocha2, Godwin Ngwu1 and Fabian Okafor1
...ndance (++). There was a dose duration dependent (p < 0.05) decrease in RBC in all the groups. There were also duration-dependent decrease in MCV values obtained in this research as against duration and dose dependent increases in MCH, and MCHC.Aspartat<...

Muhammad Riaz Gondal1,2*, Aqib Riaz4, Sultan Ahmad Rizvi2, Bushra Zulfiqar2, Waqas Naseem2, Humara Umar3, Ahmad Hussain1 and Mazher Iqbal

...sate and Paraquat at two dose levels i.e., 1.5 and 2.0 L ha-1 significantly increased the fodder yield to the tune of 189.38, 210.99 t ha-1 and 188.08, 188.94 t ha-1 respectively. Hence, the investigation lead to the conclusion that Glyphosate and Paraquat were fully effective to control weeds and enhance Fodder yield. 

...
Feng-Mei Yang1, Rui Li2, Xiu-Xue Hu3, Yong Liang4, Bo Gao3* and Wei Chen3*
...adiated by different UVB doses as well as durations, thus unveiling mechanisms underlying HSF senescence induced by Ultraviolet B (UVB). NHSFs treated under different doses (100, 200, 300 mJ/cm2) of UVB with different durations (1, 2, 3 days) were case group, while those without UVB irradiation were control group. Expressions of gene/protein were obtained with real-time quantitative PCR (RT-qPCR) and western blot;...

Muhammad Qaisar Nawaz1, Khalil Ahmed1*, Ghulam Qadir1, Amar Iqbal Saqib1, Muhammad Rizwan1, Muhammad Faisal Nawaz1 and Imtiaz Ahmad Warraich2

Impact of Fertilizer and Planting Geometery on Garlic (Allium sativum L.) Yield in Saline-Sodic Soil
...(60 kg ha-1) recommended dose (RD), (iii) 125% P of RD (75 kg ha-1) and (iv) 150% P of RD (90 kg ha-1) were used. Observations included were; plant height, bulb mass, bulb diameter, cloves bulb-1 and bulb yield. Data revealed that phosphorus @ 125% of RD with planting geometry 15cm x 20cm recorded maximum yield and yield attributes with higher economic returns, therefor, under saline-sodic conditions it is proposed as a most cost-effective management practice ...

Pankaj Kumar Jha1,2*, M. Golam Shahi Alam1 and Farida Yeasmin Bari1

Pregnancy and Lambing Rate Following Laparoscopic Artificial Insemination with Two Different Types of Diluent and Frozen-thawed Sperm Dose in Ewes
...and 50 × 106 sperm dose) on pregnancy and lambing rate following laparoscopic artificial insemination (LAP-AI) in indigenous ewes in Bangladesh were studied. A total of 78 non- pregnant ewes were synchronized for oestrus with two doses of 100 μg PGF2α (Cloprostenol) 9 days apart. The ewes were randomly assigned to one of four groups; G1 (n = 18; commercial Triladyl®/ 100 × 106 sperm), G2 (n = 21; com...

Muhammad Arsaln1, Sair Sarwar2*, Rizwan Latif1, Junaid Nawaz Chauhdary3, Munazza Yousra2 and Shahbaz Ahmad2

Effect of Vermicompost and Microbial Inoculants on Yield, Soil Fertility and Economics of Wheat under Rainfed Conditions
...e., control; recommended dose of fertilizers (160:150:50) NPK in kg ha-1; VC @ 4t ha-1; PSB; Recommended fertilizers + VC @ 4t ha-1; Recommended fertilizers + PSB; VC @ 4t ha-1 + PSB; Recommended fertilizers + VC @ 4t ha-1 + PSB were tested in the experiment using various combinations of vermicompost (VC) @ 4t ha-1 and phosphorus solubilizing bacterial (PSB) as microbial inoculants along with recommended dose of NPK fertiliz...

Zahir Shah1*, Saima Munawar1, Ihsan Ullah2, Taif Shah3, Haq Aman Ullah1, Saqib Nawaz1, Farhan Anwar Khan1 and Manoj Kumar Shah4

Combined Physico-chemical and Analgesic Effects of Electroacupuncture Plus Clonidine in Goats
..., EA combined with a low dose of 10µg/kg of clonidine provided better analgesia in experimental animals.

...
Sri Nuryani Hidayah Utami*, Andin Muhammad Abduh, Eko Hanudin and Benito Heru Purwanto
Study on the NPK Uptake and Growth of Rice under Two different Cropping Systems with different Doses of Organic Fertilizer in the Imogiri Subdistrict, Yogyakarta Province, Indonesia
...nd neem compost (1:1) at doses of 0, 3, 6, and 9 ton ha-1. The research data are presented in tables and graphs to show the effects of modification of the rice cropping system on the nutrient uptake. The results showed that the Jarwo 2:1 provided a higher N, P, K uptake compared to the Grid system. The provision of PFA had an impact on increasing the number of tillers, the number of productive tillers, and the number of panicles. The best fertilizer applicatio...
Asmat Ullah1,2, Shahid Iqbal1,2 and Furhan Iqbal2*
...e concluded that applied dose of Bauhinia variegata’s leaf extract has the potential to improve neuromuscular co-ordination in female albino and should be explored further as potential treatment for neuromuscular problems.
...

Dalal H. Sary and Rama T. Rashad*

A Comparative Study on the Impact of Compost, Humate, and Silicate on the Nutritional Characteristics of Calcareous Soil Cultivated by Soybean
... 100% of the recommended dose (compost: 7.81 t ha-1, potassium silicate: 16.67 L ha-1, potassium humate: 15.63 kg ha-1) on soil nutritional status regarding macro-nutrients (N, P, and K) and soybean yield and quality. Treatments were distributed in a randomized complete block design with three replicates. The study showed that soil applied K-H at 100% of the recommended dose has increased the available N (mg kg-1) in soil si...
MA Liman1, QI Yongxiao1, Wang Wenji2* and Zhong Qianyi3*
...m 30 to 84.85 μM in a dose-dependent manner. Moreover, quantitative real-time PCR revealed that G-Rh2 suppressed vascular endothelial growth factor (vegf) mRNA expression but not mRNA expression of its receptors (flt1, kdr). Western blot further confirmed that G-Rh2 treatment resulted in reduced Vegf protein expression. Our study suggested that G-Rh2 may exert anti-angiogenic activity by downregulation of Vegf in zebrafish embryos, thus...

Syeda Farzana Bibi* and Siraj ud Din

Unraveling the Bioherbicidal Potential, Elemental Analysis and Nutritional Evaluation of Crataeva adansonii Dc Leaf and Bark
...t results in the form of dose-dependent inhibition of frond growth. Ethanolic extract of C. adansonii exhibited 30% inhibition at 1000 μl concentration, and at the same concentration, the bark extract inhibited the frond growth by 40%. The pharmacognostic evaluation of this medicinal drug will be supportive in the detection of adulteration and quality control. Due to the herbicidal potential, it can be used in the agricultural industry. For future studies, ...
Yihong Tian, Yongmei Qi*, Sajid Naeem, Ke Gao and Yingmei Zhang*
...ility of Hela cells in a dose-dependent manner in conjunction with disrupted morphology. Moreover, spermidine caused cell damage as evidenced by elevated LDH leakage and compromised MMP as demonstrated by flow cytometry. Concomitantly, western blot analysis showed that spermidine induced autophagy by activating the LC3 conversion and p62 degradation at different concentrations and durations. However, inhibition of autophagy by 3-MA rescued the survival of Hela...

Faiqah Ramzan1,2,*, Irfan Zia Qureshi2 and Muhammad Haris Ramzan3

...ated groups of 1µg dose (p<0.01) and 1ηg dose (p<0.05) whereas the dose of 10ρg had shown no significant change. Kisspeptin doses of 1ηg and 1µg lead to significant reduction in quantity of elongated spermatids and daily sperm production (p<0.05; p<0.001), step 7 spermatids (p<0.05; p<0.001), type A spermatogonia...
Yujun Zhao and Jianping Fan*
...(p <0.05) in a dose-dependent manner. Hence, this can be concluded that Kanglaite injection can effectively inhibit the proliferation and induce apoptosis of SW480 cells, which may be correlated with the inhibition of Bcl-2 expression, the promotion of Bax expression and the enhancement of caspase activity.
...

Muhammad Jahanzaib1*, Nazakat Nawaz1, Muhammad Arshad1, Shehzadi Saima4, Muhammad Suhaib2, Muzammil Husain3, Haris Khurshid1 and Shahid Ali Khan1

Effect of Temporal Application of Gypsum on Mineral Uptake and Economically Important Morphometric Traits in Groundnut (Arachis hypogea L) under Rain-fed Conditions
...ere applied in two split doses i.e. T1 (0 %:100 %), T2 (25 %:75 %), T3 (50 %:50 %), T4 (75 %:25 %), and T5 (100 %:0 %) at the time of sowing and pegging compared with Check (T0). Results showed significant differences among treatments for yield and related agronomic traits as well as mineral concentration in response to gypsum application. The highest pod yield (3522.2kg/ha), root biomass (9.03g/ plant), and nodules (382/ plant) were observed in treatment T3. ...

Ahmed Weli Hussein Osman1,2, Rakibul Islam1, Md. Bazlar Rashid1, Abdiaziz Idiris Mohamud2,3* and Pravin Mishra4

Nanoparticle Tactics for the Oral Delivery of Insulin in Alloxan-Induced Hyperglycemia in Rat (Rattus norvegicus domestica) Model
...red alloxan injection at dose of 120mg/kg body weight intraperitoneally. Group T0 was kept for negative control while T1 was kept positive control. T2 were considered as insulin treated group at 21IU/kg and T3 as insulin with nano particles of same dose as insulin. Over the sequence of the experimental trials, observations were noted for blood glucose level, glycosylated hemoglobin, and body weight. Blood glucose levels were...

Muhammad Shahzad Akbar, Farrukh Sajjad, Muhammad Afzal, Muhammad Luqman, Muhammad Asam Riaz and Muhammad Zeeshan Majeed*

Field Evaluation of Promising Botanical Extracts, Plant Essential Oils and Differential Chemistry Insecticides against Subterranean Termites Odontotermes obesus (Isoptera: Termitidae)
... their field recommended dose rates. Results revealed that as compared to control plots, all treatment plots exhibited reduced bud and shoot damage with maximum bud germination and minimum termite infestation. Maximum bud germination was recorded in chlorantraniliprole (92.99%) and chlorfenapyr (92.03%), followed by C. aurantium (92.84%) and A. sativum (85.78%) as compared to minimum bud germination in control (40.85%). Highest bud and shoot damage was recorde...

Yuan Xing, Congming Tan, Yan Luo and Wenjun Liu* 

...he mice received varying doses of quercetin from 22-30 days (1, 10 and 50 mg / kg, p.o.) and montelukast (10 mg / kg, p.o.). Intranasal OVA has been instilled on the 21 days. Biochemical parameters, spleen weight, physiological parameters, interleukin (IL-1β and IL-6) parameters and immunoglobin-E (IgE) were calculated at the end of the experimental study. To investigate the potential mechanism of action, Paw edema and mast cell de-granulation are estimat...

Junaid Ahmad1*, Shazma Anwar1, Anwar Ali Shad2, Fazal Yazdan Saleem Marwat3, Hamida Bibi4, Farhan Ahmad1, Wajia Noor5 and Bibi Sadia5

Yield and Nutritional Status of Mungbean as Influenced by Molybdenum and Phosphorus
... out impact of different doses of molybdenum and phosphorus application on productivity and nutrients status of mungbean (Vigna radiate L.). The trial was laidout in randomized complete block design having three replicates. The experimental findings revealed that all the nutritional attributes and yield were significantly influenced with molybdenum and phosphorus addition except potassium uptake by grains and straw. Higher seed yield (772.45 kg ha-1) and harve...

Zafar Abbas1*, Shahzada Munawar Mehdi2, Muhammad Nasir3, Muhammad Ashraf4, Salma Kausar5, Nadeem Iqbal6, Muhammad Zahid Khan Nazar7, Iftikhar Ahmad3, Ghulam Murtaza1 and Ijaz Ahmad8

Evaluation of Best Dose of Micronutrients (Zinc, Iron and Boron) to Combat Malnutrition in Brinjal (Solanum melongena L.)
... the impact of different doses of micronutrients (Zn, Fe and Boron) on the yield and quality of brinjal. The experiment was laid out in Randomized Complete Block Design (RCBD) with three replications. Five different levels of micronutrients were applied. The treatment T5 i.e. (100-60-50)+ Borax (0.2) + ZnSO4 (0.5%)+FeSO4 (0.5%) exhibited maximum plant height, fruit weight, total yield, number of fuits plant-1 and survival percentage except number of leaves pla...

Hafiz Hammad Ahmad1, Mukkram Ali Tahir1*, Noor-us-Sabah1, Ghulam Sarwar1, Sher Muhammad2, Muhammad Aftab3, Muhammad Zeeshan Manzoor1 and Aneela Riaz4

Growth and Yield Response of Sunflower to Organic Amendments in Aridisol
...); T2 = NPK (Recommended dose); T3 = NK + Rock phosphate at 7 g pot-1; T4 = NPK + Rock phosphate at 7 g pot-1; T5 = NK + Rock phosphate at 7 g pot-1 + Wheat straw at 14 g pot-1; T6 = NK + Rock phosphate at 7 g pot-1 + Wheat straw at 28 g pot-1; T7 = NK + Rock phosphate at 7 g pot-1 + Rice straw at 14 g pot-1; T8 = NK + Rock phosphate at 7 g pot-1 + Rice straw at 28 g pot-1. Observations on various growth and yield parameters of crop were recorded using standar...
Naveed Akhtar1*, Muhammad Fiaz Khan1*, Sadia Tabassum1
Munawar Saleem Ahmad2 and Khan Dil Badshah3
...oups. In histopathology, dose dependent lesion and alterations in gills, liver, brain, kidney, intestine and muscles related with oxidative stress damage was observed. Genotoxicity increased with increase in time and concentration of cypermethrin. Cypermethrin is therefore extremly harmful to aquatic life.
...
Ying Liu1, Shankun Liu1, Hui Wang2 and Weihua Su2,*
...ere received the various dose of caffeic acid. After the pregnancy (19 day) the blood sample was collected via puncturing the retro arbital and collecting the fetus from all the groups. The rats, fetus weight and placental weight were calculated. The blood glucose level, serum, lipids, antioxidant, cytokines and C-peptide was recorded. GDM group rats showed the lower weight of pregnant rats, fetal and placental weight as compared to other group rats. Caffeic a...
Muhammad Nawaz Kandhro1*, Nadia Mangrio1, Aijaz Ahmed Soomro1, Zia-ul-Hassan Shah2, Ghulam Sughra Mangrio3, Nihaluddin Mari4, Zulfiqar Ali Abbasi1 and Shazia Parveen Tunio5
 
 
... important to use proper doses of balanced fertilizers to exploit the maximum yield potential of cane crop. This study focused on hypothesis that application of suitable planting methods and NPK level play a major role in improving sugarcane yield and quality. Experiment was performed under field conditions at Sugarcane Research Institute, Tandojam, Sindh, Pakistan (located at 250 25.19 N 680 32.07 E) during 2016-17, repeated in 2017-18 and data was averaged. ...
Hafiz Imran Iqbal1*, Zahir Ahmad Zahir2, Obaidur Rehman1, Rizwan Khalid1*, Abdul Waheed1, Raja Abad Raza1, Shahid Saleem1, Muhammad Rashid1, Sarosh Tariq Alvi1 and Asia Munir1
 

...n2) strains. Recommended doses of NPK were applied @ 180:140:90 kgha-1. Growth and yield of maize plants improved significantly by inoculation. Root length was increased by 32% with S1+S2+Mn2 strains at original EC. The rhizobacterial strains (either alone or in combination) significantly increased the1000-grain weight, fresh and dry plant biomass up to 35%, 36% and 48% at 6 dSm-1 respectively. Dry matter of the crop (40%) was recorded wi...
Asma Chaudhary1, Qurat-ul-Ain Ahmad1, Afia Muhammad Akram1, Sadia Roshan2 and Javed Iqbal Qazi3*
...ritoneally appeared in a dose dependent manner with symptoms like hemorrhage, swelling of the belly and anus, scale damage etc. The pathogen challenged fish were administered with Sphingomonas sp.AsCh-P3 (group-G1) and B. aerius AsCh-A7 (group-G2) treated feed in different experimental set ups. Highest Relative Percent Survival (80-90%) was recorded for fish receiving probiotic feed prior and after injection (G1b, G2b). Provision of probiotics wa...
Hagar E. Mohammed1, Ranwa A. Elrayess2 and Heba N. Gad El-Hak2*
...ated rats with different doses of A. monosperma or M. piperita alone induced severe testes histopathological lesions and histochemical alteration associated with a reduction in epididymis weight, abnormality in the sperm indices and a decline in serum testosterone levels which may have a bad impact on male infertility, on the other side, treatment the rats with the combined extract of different doses of A. m...
Praptiningsih Gamawati Adinurani1,*, Sri Rahayu1, Endang Dwi Purbajanti2, Devi Dwi Siskawardani3, Karina Stankeviča4 and Roy Hendroko Setyobudi5
...ur levels of mycorrhizae doses viz., 0 g plant–1 (M0), 10 g plant–1 (M1), 15 g plant–1 (M2), 20 g plant–1 (M3). The results indicated that the application of Rhizobium at various doses of mycorrhizae together had a significant effect on plant height 70 d (A2M1 = 53.96 cm), leaf number 70 d (A1M3 = 42.75), leaf N content (A3M3 = 5.36 g 100 g–1

Muhammad Arslan Ibrahim1*, Aneeqa Aleem2, Farkhanda Manzoor2, Shahbaz Ahmad1, Hafiz Muhammad Zahid Anwar1, Talia Aroob2 and Mansoor Ahmad3 

...l armyworm. A sub-lethal dose of 4µl of entomopathogenic NPV suspension containing 4×106 polyhedral inclusion bodies (PIB) was tested as a mortality factor against the late larval instars of S. frugiperda when natural mortality tends to decrease after each successive instar. The single-sex method was adopted in the construction of the life table. The ratio of mortality in the late instars (3rd to 5th) was greater than the early instars because of e...
Aneeqa Saleem1, Muhammad Islam1, Hamid Saeed1* and Mehwish Iqtedar2
...s were administered at a dose of 400 µg/g for 11 – 21 days. Outcome measures included serum creatinine, uric acid and BUN levels. Significant differences exist with regards to primary and secondary metabolites between both peel and pulp extractives. After 21 days of treatment in mice, only chloroform (CHL) extractives of peel and pulp demonstrated significant improvements in serum creatinine (Peel: N; 1±0.44, PC; 1.4±0.62, CHL;...
Li Shengqing1,2,3, Zhang Xiyun2,3, Liu Shengcai2,3, Hu Guoyuan2, Fan Yuxia2,Liu Huaixin2, Wang Tingting2 and Zhang Yanming1*
...lyses. The lethal median dose (LD50) values of intragastrically and orally administred type D botulinum toxin in wild plateau pikas, plateau zokors, and Microtus fuscus are calculated through Horn’s method and the improved Karber method. The ability of the toxin to prevent and control rodent damage is assessed through plot experiments. The safety of type D botulinum toxin toward nontarget animals, such as yaks, Tibetan sheep, dogs, vult...
Chaman Ara1*, Asmatullah1, Saima Hanif1, Shagufta Andleeb2, Beenish Zahid3 and Madeeha Arshad4
Saba Afzal1, Sohail Raza1,*, Masood Rabbani1, Sehrish Firyal2, Imran Altaf1 and Zahra Naeem1
...issue culture infectious dose (TCID50). The results showed that 2.5 µM concentration of the ivermectin is non-toxic to the Vero cells. At this concentration, PPRV titre was significantly reduced (p < 0.001) by two log to 103.0 TCID50/0.1 mL as compared to virus control 105.5 TCID50/0.1 mL. Moreover, the ivermectin exposure after the viral attachment and entry steps able to reduce virus titr...

Saima Naz1*, Ahmad Manan Mustafa Chatha2, Saba Saeed1

...r LC50 but higher lethal dose. Two fish were different in size as well. A significant positive correlation of metallic ion concentrations was observed with sodium, potassium, carbon dioxide and electrical conductivity whereas an inverse relationship was obtained with dissolved O2 for both Labeo rohita and Cirrhinus mrigala test mediums. It is concluded that acute concentration of nickel is lethal for both fish species with a significant difference of LC50 and ...
Md. Alal Hossen1, Mohammad Amzad Hossain1*, A.K.M. Munzurul Hasan1,2, Bipresh Das1, Sohel Mian1, Mohammed Mahbub Iqbal1
 
...on approach. The S-GnRHa dose optimization and embryonic-larval development study were conducted in a freshwater condition in order specify optimal dose of synthetic hormones in induced breeding. The synthetic GnRHa was used as induction agent where male injected half of the doses of female and a control without S-GnRHa was assigned. The stages of embryonic development were observed under ...
Yawang Sun, Yongjiang Wu, Jingbo Chen, Zili Wang, Juncai Chen, You Yang and Guozhong Dong*
...n species increased in a dose-depend manner. Cellular concentrations of oxidative damage markers were positively correlated with applied LPS concentrations. Total antioxidant capability and the activity of superoxide dismutase (SOD) increased with increasing LPS concentrations. Gene expression of antioxidants including SOD, NADPH-quinone oxidoreductase 1, and hemeoxygenase 1 were significantly increased at the LPS concentrations of 12.5 and 100 ng/mL. Both Fan...
Muhammad Afnan Rabbi, Iqtidar Hussain*, Ejaz Ahmed, Muhammad Saad and Aitezaz Ali Asad Shahani
...ss the effect of various doses of N and P2O5 with combination of exogenous application of naphthalene acetic acid levels in late sown wheat in agro climatic conditions of Dera Ismail Khan, KP., Pakistan. Data registered on agronomic parameters i.e. plant height (cm), spike weight (g), spike length (cm), number of tillers, weight of 1000 grains (g), number of grains spike-1, biological yield (kg ha-1), yield of grain (kg ha-1), yield of straw (kg ha-1), product...

Khan Tamoor1*, Hafsa1 and Hanif Maryam2

...and F. oopoda at highest dose of 3 g/ liter which was followed by 72% of N. cateria and 49% by A. santolina at the same dose. However, essential oils of A. santolina showed the highest mortality (79%) as compared to Z. multiflora (74%), F. oopoda (70%) and N. cateria (68%) at the same dose of 1.2 ml/ liter. While results of fixed oils showed maximum mortality of 74% by F. oopoda followed b...

Hiam M. Fakhry and Assem A.A.

...disease zeolite (1 μg/dose) vaccine, The second group was vaccinated with foot and mouth disease oil vaccine and Third group was vaccinated with foot and mouth disease ( oil + zeolite ) vaccine. The cellular immune responses were monitored in different tested groups that revealed the immune responses in sheep continuous with the permissible protective level is (0.280) Delta Optical Density till 8th for zeolite and oil vaccine vaccine while till 10th week po...

Walaa Abd El-Fatah S. Metwally1, Ismail M. Reda2, Ahmed A. El-Sanousi2, Mohamed Abd El-Khalek Ali2

...ried in the HA units per dose and also differed in the ratios between two reassortant strains (Chicken and duck strains) of AI. The results of testing humoral immunity revealed that the prepared vaccines with Montanide ISA70VG containing 350 HA unit/dose were high in antibody titer than vaccines containing 256 and 100 HA unit/dose. The prepared vaccines with Montanide ISA 70VG containing 2...

Allam A. Megahed1; Hoda M.A. Waziri2; Khaled A. El-Dougdoug3; Badawi A. Othman3; Sirag M. Lashin1; Mohamed D. Hassanin1 and Mahmoud A. Ibrahim4

...and BNYVV by 5 injection doses each, using different injection types obtained from rabbit bleedings 10 days after the last injection had the titer of 1:2048 and 1:1024, respectively by indirect-enzyem linked immunosorbent assay (I-ELISA) technique. The produced antisera were evaluated and compared with foreign antisera using tissue printing immunoassay (TPIA) and dot blot immunoassay (DBIA). The produced antisera were found more efficiency in development the p...

Samah A. Mokbel, Ahmed K. El-Attar

...v>radiation at different doses - 5 gray (Gy), 10Gy, 15Gy, 20Gy and 25 Gy- emitted
from cobalt 60 (60Co) for 30 minute. All applied doses resulted in phytoplasma-free
hibiscus plantlets with different survival activity. The presence of phytoplasma 16Sr
DNA was examined using PCR detection before and after treatments. The different
treatments of radiation resulted in different su...

Amir M. Walaa1 ; Ausama Yousif1; Walid H. Kilany2; Magdy El-Sayed1; Ahmed A. El-Sanousi1

...s were challenged with a dose of 105.5 EID50/bird of Variant 2 genotype (1494) IBV through oculo-nasal rout. Blood samples were collected randomly from 10 birds from each group at day 7, 14, 21, 28, 35 and 42 . Organs of 3 birds/each group were collected (trachea, bronchi and kidneys) for PCR at 3, 7 and 10 days post vaccination and post challenge as well. Groups 3 &4 showed high protection with all serological tests. Based on our findings Vaccine Manufact...
Eman A. Ahmed1, Osama Y. shalaby2, Emad F. Dwidar2, Samah A. Mokbel1 and Ahmed K. El-Attar1
...1), irradiation by three doses (3, 5 and 10 Gy) of gamma ray and natural compound (1ml of garlic juice). All treatments proven to be a very useful effect against phytoplasma, except concentration 25 mgL-1 of tetracycline hydrochloride. The findings of this study have proven treatment at lower dose of gamma rays (3 Gy) of efficient methods on growth promotion.

...

Ola Youssef 1; EL-Deeb A.H.2 Nassif S.A.1 and Ahmed A. El-Sanousi 2.

...400, 3750 & 4000 PFU/dose for batch A, B, C, D, and E respectively. The selected
batches safety was satisfactory by 10 fold field doses injection in SPF chicks. The challenge test results
revealed 80% protection for A, B and C batches while D and E batches gave 90% protection. The
shedding of challenge virus was significantly low with mean of 2 logs 10 in the vaccinated group
Abeera Razzaq1, Sajid Abdullah1, Huma Naz2*, Khalid Abbas1, Laiba Shafique3 and Qingyou Liu3
...d to the four sub-lethal doses (26.61, 13.30, 19.98 and 7.98 mgL-1) of Cr+Cr mixture for 28 days and blood was sampled after 7 days interval. A group (n=10) of fish were also kept in clean water (negative control=NC) and cyclophasphamid (positive control=PC), separately. Blood from caudal vein of fish was collected to see the micronuclei (MN) and de-shape nuclei (DN). Results showed that test dose 26.61 mgL-1...

Rana A. Rabiea1, Mohamed Fawzy2, Mohamed H. Khodeir3 and MokhtarM. EL-Tarabili2

...nistration of the second dose and remain stable up to 24 weeks post vaccination.
Follow up avian influenza antibody titers using HI test, peak titer (64 log2) was detected in group-2 and
group-3 by the second week after receiving the second dose then began to decrease in both groups by
third-week post the second dose to reach the zero level at week twent...

Youssef A. Elgharbawy1, Mervat M. Ali1, Ayman H. El-Deeb2, Mohamed A. Shalaby2

...on of minimal protective dose (MPD) of prepared inactivated LSDV. The MPD was 1.5 ml of the inactivated virus and the vaccine was prepared by adding equal volume of the adjuvants (Montanide ISA 50 and Montanide ISA 206 ) to the total quantity 3ml of the vaccine. The prepared vaccine tested for determination of immunological response against the vaccine with ISA 50 and ISA 206 adjuvants and the results was compared. The results of cellular and humoral immune re...

Muhammad Ehsan Safdar1*, Samra Ammara1, Muhammad Sikander Hayyat1, Shahbaz Hussain2, Muhammad Mansoor Javaid1, Abdul Rehman1 and Amjed Ali1

..., viz. lactofen complete dose (180 g a.i. ha-1) alone, lactofen complete dose + adjuvant, lactofen 80% dose alone, lactofen 80% dose + adjuvant, lactofen 60% dose alone, lactofen 60% dose + adjuvant and a control (no herbicide). It was found that lactofen full <...

Ibadullah Jan1*, Iqbal Munir2, Inamullah Khan3, Syed Muhammad Suhail4 and Aqib Iqbal2

... the ear edema at a high dose. However, at 20 mg/kg for 60 minutes, the impact was less important. In vivo anti-inflammatory testing revealed that Dosiflavone significantly (p<0.05) reduced the biphasic inflammatory events caused by carrageenan in a dose-dependent way, with the highest levels at 40 and 80 mg/kg. Dosiflavone showed excellent (p<0.05) analgesic activity with anti-nociceptive effect in hot plate test in a...

Ahmed Ali Moryani1, Nasir Rajput1*, Muhammad Naeem1, Atta Hussain Shah1 and Hidayatullah Soomro2

...e (Group E and F) at the dose 2ml/L to the coccidiosis challenged broiler chickens improve the overall performance and liver function.

...

Dilan Ozmen Ozgun1, Gonca Alak2, Arzu Ucar2, Sinan Bilginer3, Halise Inci Gul3, Mahmut Kocaman2, Cem Yamalı3, Veysel Parlak2, Muhammed Atamanalp2, Ahmad Maslat4 and Telat Yanık2*

...ecreased with increasing dose from 0.25 to 2.5 mg/L of B4 (p<0.05) compared to control. There were no differences between control and DMSO group (p>0.05) with respect to all tested properties. It is suggested that B4 should be investigated further for possible usage in aquaculture industry to produce healthy fish.
...

Haroon Ur Rashid1*, Nazia Tahir2, Muhammad Zamin3, Naveed Shehzad4, Aman Ullah2, Bibi Zainub5 and Farooq Azam6

...1/4th of the recommended dose) was assigned to sub plots (Factor B). Data were recorded and analyzed for dry biomass (g) of total weeds 60 DAS, leaf area (cm2), leaf area Index (%) and Stover yield (Kg.ha-1). Integration of tillage regimes and various allelopathic treatments had significant effect on tested parameters. However, the efficacy of surface mulches was more pronounced than atrazine foliar application @ 0.50 kg a.i ha-1 and allelopathic plants water ...

Muhammad Jan1*, Muhammad Ashraf Sumrah1, Shoaib Akhtar1, Inam Ul Haq2, Muhammad Ramzan Anser1 and Iqra Yasmin1 

...ive orchards in a proper dose. Olive intensification for new orchard enhanced fertilizer use especially Nitrogen (N), Phosphorus (P) and Potassium (K) and in micronutrients especially Boron (B) to control alternate bearing of olive. In Pakistan, olive plantation is an initiative to minimize the Olive import, and to maximize olive plantation in Pothwar area as well as control climate change. There is no trend for fertilizer application among the Pakistani farme...

Sajida Batool1, Saira Batool1, Sitara Shameem1, Fatima Khalid1, Tahira Batool2, Summera Yasmeen1, Saima Batool3*

...trazine was given at the dose of 200 mg/kg body weight through gavages for 28 days while the control (Cnt) group remains untreated. On the 29th day, all animals were sacrificed to recover liver for histological preparations. Atrazine (ATZ) caused various hepatic implications in the treated animals. ATZ exposure caused a significant decline in mean body and liver weight as compared to the Cnt group. The histopathological findings in ATZ administered group inclu...
Tanmoy Mandal1 and Sunil Kr. Ghosh2*
... is concluded that lower dose of imidacloprid mixing with azadiractin/polygonam/spilanthes extracts will be environmentally sound and eco-friendly and is recommended for leaf miner control to promote organic farming.
...
Chao-Qun Shi1, Hong-Ying Lin1, Jin-Qing Zheng1, Fan Yang1, Kwame Ayisi Lartey1, Dan-Ju Kang1, Hwa-Chian Robert Wang2, Ravi Gooneratne3*and Jin-Jun Chen1*
...+ 0 mg/kg TFCO), low dose (E. coli + 10 mg/kg TFCO), medium dose (E. coli + 40 mg/kg TFCO), and high dose (E. coli + 160 mg/kg). TFCO was administered by gavage 3 h post intraperitoneal (i.p) E. coli injection. Serum IgM, IgA, IgG, TGF-β1 mRNA expression in duodenal villi, and histopathology of duodenum were also studied. TFCO significantly incre...
Mengke Wang1, Shucheng Huang2, Cai Zhang1*, Haizhou Gong1
Shunan Cuan1, Shuaishuai Wang1, Qi Shao1, Wenhao Xu1, Sudan Meng1
Pengfei Li1, Yuqin Wang1 and Zijun Yang1
...er injury, while no dose dependence was found in this study.
...
Mona Mohammed EL-Derbawy1, Eman Naser Hafez2*, 
Mona Abdel Daym Abd Rabbo1, Nagwa Ibrahim Toaleb3,
 Saedia Abdel Hady Sayed El-Ahl1 and Bahaa Eldkeen Wade EL-Aswad4 
...r exposed to attenuating dose of 400 Gy gamma radiations. The study was conducted on fifty two individual sera samples divided as follows: Group І included 21 obtained from patients who were positive for schistosomiasis and negative for other parasitic infections; Group ІІ included 18 sera from patients who were negative for schistosomiasis and positive for other parasitic infections; (3) fascioliasis, (5) amoebiasis, (7) toxoplasmosis and (3) hydatidosis a...
Zheng Yan1,2,*, Shuang Liu2, Ai-Qing Liu2 and Hai-Yan Wang2
...he low, medium, and high dose groups were 1.5, 5.0 and 10 mg/animal per day, respectively. Then, skin elasticity was measured using a cutimeter dual MPA 580. The concentraions of three type of collagens, hyaluronic acid and hydroxyproline in skin tissue were also determined. The results indicated that the oral administration of elastin peptide greatly improved the skin elasticity, accompanying with significantly upregulated expression of hyaluronic acid and hy...
Zafer Karslı1,*, Dilek Şahin1, Meryem Öz2, Ünal Öz2 and Orhan Aral2
... (Es) at three different doses (20, 40, 60 mg kg-1) and control feed was without hormone. All six experiment groups receiving experimental diets and control were conducted in 3 replicates in 21 aquariums for 3 months in the first experiment. L. caeruleus were fed orally with these hormone-supplemented feeds and growth parameters, sex conversion and survival rate were examined. In the second experiment, fish from the first experiment were fed ...

Mohammed Abdel-Mageed Abdel-Aziz Abdel-Mageed1, Eman Alsayed Hammad2*, Nashaat Abdel-Aziz Mahmoud1 and Anas Farag El-Mesalamy1

...ut adding the extract as doses to the soil reduced the numbers of nematodes better than other methods of application.

...

Mahmoud M.A.Youssef and Wafaa M. A. El-Nagdi

...easing gamma irradiation doses. When tomato plants infected by root-knot nematode, Meloidogyne incognita were exposed to combined elevated atmospheric CO2 concentration (+100 ppm) and higher temperature (+2oC), tomato shoot dry weight and nematode control were increased compared to prevailing conditions.

...

Mohamed S. Khalil

...revealed that all tested doses of milbemectin suppressed galls (ranged from 50.59 to 75.50%, of both experiment) and egg masses (ranged from 66.67 to 87.01%, of both experiment) significantly, while fenamiphos recorded moderate reductions. Also, the measured plant indices were augmented with all applied treatments. Therefore, from this study it can prove that milbemectin possess efficacy on galls and egg masses of root –knot nematode (M. javanica).

...
Junli Liu1, Tongfang Yang2 and Lisheng Wu3*
...P<0.05). All were dose-dependent. LINC00857 targets and regulates miR-340. Overexpression of LINC00857 or inhibition of miR-340 evidently reduced the expression levels of P21, Caspase-3 and apoptosis in U2OS cells after homoharringtonine treatment, and remarkably improved cell survival rate and colony formation (P<0.05). It is concluded that homoharringtonine can inhibit the proliferation of osteosarcoma cells and induce apoptosis by regulatin...
Syed Shahid Imran Bukhari1*, Nusrat Jahan2, Muhammad Khalil Ahmed Khan3, Mariam Zaheer1, Sabir Javed1
...oxic limits of different doses of gel extract in diabetic induced albino mice. Male albino mice, weighing (25±5g) were divided into three groups; Group 1: normal (non diabetic nontreated), Group 2: diabetic non treated (DNT), Group 3: diabetic treated (DT) mice. Group 3 was treated with three doses of A. barbadensis (200 mg/kg, 300 mg/kg and 400 mg/kg) per day for 14 days were assigned as DT1, DT2 and DT3 respectively...
Amr N. El-Shahat1, Refaat G. Hamza1,*, Ashraf M. Mounir1 and Madeha N. Al-Seeni2
... 3 days up to 8 Gy total doses) induced biochemical and oxidative damage in rats when compared to control group. In GFJ (10ml/Kg B Wt. /day) treated irradiated group, there were noticeable decreases recorded in lipid contents, concentration of serum urea, creatinine and uric acid, glucose level, activity of some liver enzymes and liver and kidney TBARS levels with remarkable increases in level of HDL-C, insulin and showing elevation in GSH level and
Noor Bad Shah Khattak1, Hamayun Khan1, Muhammad Tarique Tunio2, Shakoor Ahmad1, Nazir Ahmad3, Syed Murtaza Hassan Andrabi4, Obaidullah5, Ihsan Ali1,5,* and Nan-Zhu Fang5,*
Nacira Djabali1*, Souad Dougat2, Wahida Haddadi2 and Lamis Fadhli2
...pplied at two increasing doses: 50 ppm and 150 ppm for five successive weeks, orally. The level of the circulating gonadotropin hormones luteinizing hormone (LH) and follicle stimulating hormone (FSH), the level of testosterone, the biological characteristics of the sperm, the weight and the histopathology of the testes were studied. The results obtained show a significant dose-dependent decrease in LH, FSH and testosterone ...

Dewi Ratih Ayu Daning1,2, L.M. Yusiati1, C. Hanim1, B.P. Widyobroto1*

...ims to evaluate numerous doses of galangal EO (EO) and pure cineole for the relative abundance of rumen microbes and its fermentation parameters in vitro. It applies five treatments with six replications and uses completely randomized design to analyze the data. Only if do such differences exist, the Duncan Multiple Range Tests (DMRT) were conducted. The treatments consist of the following galangal EO doses: 0, 30, 60, 120 &...

Imran Ali Chandio1, Muhammad Nawaz Kandhro1*, Qamaruddin Jogi1, Ghulam Murtaza Jamro2 and Siraj Ahmed Channa3

... block design. Different doses of nitrogen as broadcasting and fertigation (0, 75, 100, 125 kg N ha-1 in two and three equal splits given at sowing time, 1st, 2nd and 3rd irrigations, respectively) were applied to two sunflower genotypes (HO-1 and Hysun-39). Data analysis revealed nitrogen fertigation, genotypes and their interaction substantially (P≤0.05) affected growth and yield traits of sunflower. Greater seed yield (kg ha-1) and the oil content (%) we...
Shoaib Ahmed Pirzado1,2*, Wu Zhengke1, Adanan Purba1, Chen Jiang1, Huiyi Cai1, Chen Guilan1 and Guohua Liu1*
...dition of azomite at the dose of 0.25% and 0.50% in the diet had beneficial effect on growth performance, retention of nutrients, digestive enzymes and bone mineralization.

...

Arkan B. Mohammed*, Ammar S. Abdulwahid, Samah M. Raouf 

...chemical parameters in a dose-dependent manner.

 

Keywords | Antioxidants, Egg production, Laying hens, Thyme
 

...

Chunjie Song1, Shangquan Gan2 and Xiaoyun Shen1,3*

...andomly divided into low-dose group, high-dose group, gentamicin sulfate group and control group with 5 Procapra przewalskii in each group. The P. przewalskii in modified Yujin powder group were given Yujing powder once every morning and evening, 3, 4 mL/ (kg·BW) for the low-dose group and high-dose group, respectively. The P. przewalskii were inj...

Yin-Hua Wang1,2, Yi-Bing Zhu1, Li Jiang1, Bin Du3 and Xiu-Ming Xi1*

...th of stay (LOS) in ICU, dose adjustment time, analgesic and sedative agent costs, short-term mortality, and adverse events potentially relevant to the study drugs. Data analysis will adopt an intention-to-treat approach. This trial will demonstrate the probability that remifentanil can reduce the duration of MV in long-term ventilated patients in critically ill patients compared to fentanyl.

...

Safdar Ali1*, Muhammad Amir Hanif1, Muhammad Umar1, Amir Manzoor1, Obaidullah Shafique1, Bashir Ahmad Khan2 and Ijaz Ahmed3

...e14% w/w) at recommended doses. A weedy check and a weed free plot were also kept for comparison. Results showed that in comparison to control plot (weedy check), there was 73.41% increase in the grain yield of wheat where double spray of Ally Max was done and it was followed by 58.28%, 54.78%, 51.28% and 36.59% where double spray of clean wave, Buctril Super, Starane Mand single hand weeding were applied respectively. Similarly, there was 70.1% decrease in th...

Raheela Naz1*, Muhammad Aftab1, Ghulam Sarwar2, Ana Aslam1, Qudsia Nazir1, Asifa Naz3, Abid Niaz4, Farah Rasheed1, Amina Kalsom1, Nisa Mukhtar1, Sadia Sultana1, Ifra Saleem1, Arfan ul Haq1, Muhammad Arif1, Aamer Sattar1, Sarfraz Hussain5 and Muhammad Adnan Rafique6

...ut below the recommended doses. As we know that for the better quality and yield of crops, time and method of fertilizers application are the most important factors. Some growth stages are very sensitive, at those stages of growth; the addition of fertilizers is more responsive than others. In order to nutrients to become available when the plant needs them and to make maximum benefits, fertilizers should be applied at the right time. In this experiment, impac...

Dabeeran Zehra1, Zahida Memon1, Shumaila Usman2,*, Almas Jabeen3, Kauser Ismail1 and Rehan Ahmed Siddiqui2

...e combine effects of low dose of Azithromycin with Sorafenib in HepG2 cell line. Co-treatment of Sorafenib and Azithromycin showed enhanced inhibition of cell growth and suppressed the MAPK pathway associated with cellular proliferation, however the effects on cellular apoptosis were found to be insignificant.

...

Neda Amani1, Mehrdad Shariati1, Rahim Ahmadi2,3*, Mokhtar Mokhtari1 and Saeed Khatamsaz1

...d HCT cells to cytotoxic dose of testosterone enanthate led to significant increase in gene expression and activity level of caspase-3 and -9, but no significant change in iNOS, MMP9 and caspase-8 expression level. MMP9 expression level significantly decreased in HCT cells, however, did not change in AGS cells exposed to cytotoxic dose of testosterone enanthate. Treatment of HCT and AGS cells with testosterone enanthate indu...

Zein Ahmad Baihaqi1,2, Irkham Widiyono3*, Bambang Suwignyo4, Amado A. Angeles5 

...allenges to focus on the dose of administration, the structure of the tannin itself, the substitution of other ingredients and also includes the types of animals given treatment.

Keywords | Environment, Methane, Ruminant, Tannin, Global warming 

...

Hong Yin*, Dan Yang, Ji-Jie Liu, Jing-Wei Ding and Dan-Dan Cui

...ithout or with different doses of β-CM-7 for 30 days. At the end of the experiment, all mice were collected for serum and tissue samples. Histopathological studies showed the tissue protective role of β-CM-7 in aged mice. The treatment of β-CM-7 in aged mice significantly increased the triglyceride (TG) level with decreasing high density lipoprotein (HDL) level in serum. The superoxide dismutase (SOD), glutathione peroxidase (GPx) activities and...

Hafiz Adnan Ahmad1,2*, Muhammad Aslam2, Salman Gul2, Tariq Mehmood2 and Munawar Ali Munawar2

...edema method at 10 mg/kg dose. Among all derivatives, two compounds 4g and 4b displayed better anti-inflammation potential than standard drugs celecoxib and indomethacin. While the anti-inflammation profile of compounds 4h, 4e and 4f during in vivo screening was also comparable to celecoxib and indomethacin. The structure-activity relationship (SAR) was also discussed with the reference of substituent nature. Present results showed that newly synthesized hybri...

Ramy S. Yehia1,3, Essam A. Shaalan2* and Hashem M. Al-Sheikh1 

...ate and 4 replicates per dose of fungi) were subjected to five doses from each fungus (101, 103, 105, 107 and 109 conidia/ml) in plastic cups for one min then transferred to a clean one. Both test and control cups were incubated for 7 days to determine LC50, 90 and EI50, 90. Joint action of these fungi with three botanical oils (celery, ginger and sesame) as well as influence of sublethal dose...

Doaa Sh. Mohamed1, Nema S. Shaban2 , Mai M. Labib3, Olfat Shehata4 

...r a period of two weeks (dose every five days) and almond oil group: Mice were administered almond oil orally (2.26 g/kg) using oral gavage daily over a period of three weeks, one week prior to the doxorubicin injection and two weeks along with doxorubicin injection. The effects and mechanisms of doxorubicin on superoxide dismutase activities were elucidated by molecular docking studies. Treatment with almond oil attenuated lipid peroxidation, improved superox...

Nan Jiang, Tong Liu, Jimin Liu and Guobin Tang*

...cts of inhalation of low-dose budesonide powder combined with pulmonary rehabilitation in the treatment of bronchial asthma, and to explore the mechanism of action. In this study, 180 patients who had been diagnosed and treated for bronchial asthma in our hospital were enrolled as research objects. They were divided into experimental group accepting inhalation of low-dose budesonide powder combined with pulmonary rehabilitat...
Ranjhan Junejo1*, Shahabuddin Memon1, Muhammad Usman Shar2, Ayaz Ali Memon1 and Fakhar-un-Nisa Memon3
... 3 mg/trap/day pheromone dose and 5 mg/trap/ day EA captured the maximum number of adult red palm weevils and effective trap density was found to be 11 traps/ha, while further higher trap density has no significant difference. Moreover, the darker color traps catch a significant higher number of weevils as compared to white or light-colored bucket traps.

...
Afsheen Noman Saddar1, Anila Naz Soomro2*, Sadaf Tabasum Qureshi1, Syeda Saleha Hassaney1 and Mukhtiar Ahmed Mahar2

El-Kholy KH1, Tag El-Din H1, Tawfeek FA2, Sara HM Hassab1* 

... values were observed in dose 7.5 ml SLAE/kg diet. Also, SLAE addition result a dose-dependent decrease (P<0.05) in ACTH levels in laying hens. The treatment did not affect T4 and LH hormones (p=0.1470 and 0.2764, respectively). Regarding reproductive traits, the treatment increased the hatchability to total and fertilized eggs, maximizing in groups treated with 5 and 7.5 ml SLAE/kg diet. There was a non-significant asso...

Arman Sayuti1, Hamdan Hamdan2, Miftahul Jannah3, Safriadi Safriadi3, Teuku Nasri3, Tongku Nizwan Siregar2*

...ee consecutive days at a doses of 1.0, 0.5 and 0.3 mL each, whereas rabbits K2 were injected with BPE for three consecutive days at a doses of 1.0, 0.5, and 0.3 mL each. After the third injection, rabbits of K1 and K2 groups were mated with male local rabbits. For measurement of steroid hormones concentration using an enzyme-linked immunosorbent assay (ELISA), blood samples were collected on day 0 (the day when rabbits mated...

Evrim Sönmez

...n be said that different doses of B. bassiana are quite effective on the mortality rates of A. obtectus adults, the number of eggs they lay, and especially the number of adults emerged from beans.

...

Amal Hamad1, Ashraf M. Abu-Seida2*, Faisal A. Torad2, Nahed S. Thabet3, Shabaan M. Gadallah1

Ji Xu, Zhonghua Liu, Zhenhai Cui and Wenhai Zhao*

...rences between different dose groups of GSTT (P <0.05) . After miR-99a overexpression, the levels of inflammatory factors IL-6, TNF-α, IFN-γ were significantly reduced (P <0.05), the apoptosis rate was significantly reduced (P <0.05), and protein levels of Bax and cleaved-caspase3 were significantly decreased (P <0.05), and the protein level of Bcl-2 was increased significantly (P <0.05). Inhibition of miR-99a expression could attenu...

Ishrat Younus1,2 and Afshan Siddiq1*

...mined at three different doses (50, 100 and 200 mg/kg) using different pain models (writhing induced, tail flick) and yeast induced pyrexia tests, respectively. The extract exhibited significant (p < 0.05) in vivo analgesic and antipyretic potential in term of % writhes inhibition, increased latency time and reduced rectal temperature when compared with control. The extract displayed noteworthy analgesic and antipyretic capabilities especially at the

Rabia Bibi1, R. Muhammad Tariq2, Samir A.M. Abdelgaleil3 and Munawwer Rasheed1, 4*

...after 96 h exposure at a dose of 2.2 mg/cm2 with most of the seaweed extracts against S. oryzae and C. maculatus. While treatment with J. rubens and G. foliifera provided only low to moderate toxicity to both tested species.

...
Saeed Akram Khan1, Shahid Sherzada1*, Muhammad Ashraf1, Durr-e-Shehwar1, Sonia Iqbal1, Usman Atique1,3, Farzana Abbas1, Sohail Ahmad2 and Muhammad Sultan Haider4
... to place as well as the dose of ovaprim. The present investigation is focused on possible impact of different temperatures on the induced spawning behavior of C. mrigala. The factors investigated include the ovulation time, embryonic and larval development, and yolk sac absorption induced at 4 different water temperatures viz. 26, 29, 32 and 34 ºC. C. mrigala displayed the maximum release of eggs, fertilization and hatching rates at 29 ºC. The maxim...

Jun Zhang1*, Xiaocao Xu2 and Min Cao2

...nistration of a reminder dose based on antibody titer is recommended in these individuals.

...
Yunilas Yunilas1*, Nurzainah Ginting1, Tri Hesti Wahyuni1, Muhammad Zahoor2, Nelzi Fati3 and 
Ahmad Wahyudi4
...ns. Factor I was various doses of MOL (1 %, 3 %, 5 %), and Factor II was different fermentation times (7 d, 14 d, 21 d). The variables observed included texture, color, odor, and taste. The results showed that the MOL dose and fermentation time had a very significant effect (P < 0.01) on silage’s texture, color, and odor. In addition, the MOL dose and fermentation time have...

Mirtneh Akalu1,2*, Takele Abayneh2, Esayas Gelaye2, Behailu Tefera2, Teferi Degefa2, Vemulapati Bhadra Murthy1 

...nd immunized with single-dose and booster-dose of 0.15 mg/ml vesicle preparation. Sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) assay of the partially purified MH-OMVs revealed approximately ten protein bands ranging from 25 to 104 kDa. Hemagglutination inhibition (HI) assay confirmed that the immune response was significantly increased in both single-dose and booste...

Wei Cui1, Yanwei Du1, Lijuan Jiang1, Yan Wei1, Yuguo Li1, Wenfeng Zhang1* and Ling Zhang2*

...h-fat-sugar diet and low dose of streptozotocin for 4 weeks to observe the body weight, fasting blood glucose, etc. The pathological changes of hippocampal CA1 region were observed through hematoxylin-eosin staining, and the expression of related proteins was detected. The results showed that, after BHD intervention, the degree of apoptosis of PC12 cells injured by HG was significantly reduced, and the cell proliferation was significantly increased. In model g...

Ahlam G. Khalifa1*, Walaa A. Moselhy1, Hanaa M. Mohammed2 and Khaled Abdou1 

...n loaded silica Nps at a dose of 8.795 mg/kg BW. The group (IV) obtained deltamethrin loaded chitosan Nps at a dose of 30.44 mg/kg BW. All remedies were administered by oral gavage 5 days a week for one month. The deltamethrin group showed a highly significant elevation in chromosome aberrations. Also, the ratio of polychromatic erythrocytes to normochromatic erythrocytes proved that deltamethrin had a stronger cytotoxic eff...

Wafaa M.A. Ghoneem*, Muhammad M. Shaklouf, Ali M. Ali and Mohammed H. Bakr

... composition. While, overdose of LAFP might have a negative effect on digestibility.

...

Zhongqing Wang1, Qiuyue Wu1, Ruiling Ye1, Fazul Nabi1,4, Yangfei Shang1, Sarfaraz Ali4 and Juan Liu1,2,3*

...PG), AMP low/middle/high dose (LG/ MG/ HG) groups respectively, (n=12). The mice were induced by diarrhea with E. coli (5×107CFU) via i.p injection (0.5 mL/time/d) after seven days of pre-administration except in CG. After the induction of the diarrhea, the pathological signs and the quantity of iIELs in small intestine and the mRNA level of IL-6 and TNF-α in duodenum were analyzed by qRT-PCR from all groups at 6 h and 4 d, respectively. IG group s...

Feng Xu, Weijing Fan and Guobin Liu*

... with rutin in different doses. The cell activity and apoptosis rate of HUVECs were analyzed by CCK-8 method and flow cytometry, respectively. The levels of intracellular catalase (CAT), superoxide dismutase (SOD) and malondialdehyde (MDA) were measured using commercial kit, and expression levels ofNEXN-AS1 and miR-410-3p were detected using real-time quantitative PCR analysis. The dual luciferase experiment was applied to verify the targeted relationship betw...

Tao Ren1, Guiqiu Cao2, Xiao Han3, Feng Tan1, Qiaoli Chen4, Shicheng Yang5 and Haiyan Zhang6*

Barirah Rehman Talpur1, Zaheer Ahmed Nizamani1*, Imdad Hussain Leghari2, Mansoor Tariq1, Aisha Rehman3, Shahnawaz Kumbhar1 

...t is concluded that high dose (200mg/l) of Sodium Fluoride causes liver and kidney dysfunction in both species along with lesions in digestive system of broilers.

Keywords | Fluorosis, Rabbits, Broilers, Liver, Kidney 

...
Ade Djulardi1*, Robi Amizar2, Tigor Sanjaya1
...red milk powders up to a dose of 0.50% did not affect the performance of quail aged 6-9 weeks. Numerically, higher income over feed cost (Rp. 274,272) was attained from the quail layer fed with 20% protein.
 
Keywords | Expired milk powder, Protein level, Performance, Laying Japanese quail
...
Chinar Mustafa Mohammed1*, Thamer M. Bashir1, Omar A.M. Al-Habib2, Farhad Ramadhan1, Mohammed Bassam1
...inistration of different doses of taurine on arrhythmia induced by social isolation in vivo after. The ECG signals and parameters were recorded and analyzed with the aid of Bio Amp of ADInstruments data acquisition system and LabChart software. The results showed infusion of Taurine 1mg/kg/hr, 2.5mg/kg/hr and 10mg/kg/hr non significantly change heart rate (BPM), QRS intervals, S amplitude (mV), T amplitude (mV), ST height (mV), JT height (mV), QT intervals (s)...
Emtenan M. Hanafi1*, Fouad M. Tawfeek2, Walid S. El Nattat1, Moetazza M. Alshafei3, Seham S. Kassem3, Kawkab A. Ahmed4, Enas N. Danial5, Hagar Elbakry3, Hoda S. El-Sayed2
...e should be paid for the dose and frequency of administration of any polyphenol or health potentioators.
 
Keywords | Spirulina platensis, Bifidbacterium longum, Spermatozoa profile, Male fertility
...
Ahmed Mohamed Elmahdy1*, Naglaa Mohammed Alkalamawy2
...subcutaneous therapeutic dose of ivermectin (200 micrograms per kilogram body weight), once monthly for 2 consecutive months. Group four: This group of rabbits was given an orally aqueous extract of O.M. (200 milligrams per kilogram of body weight) once daily for sixty consecutive days. and a subcutaneous therapeutic dose of ivermectin (200 micrograms per kilogram of body weight), once monthly for 2 consecutive months. The d...

Muhammad Bakhtiar1*, Fayaz Ali Niaz2, Asim Muhammad2, Mamoona Munir3, Wajiha Seerat4, Sadiqullah Khan5, Ghulam Yaseen6, Muhammad Noman Khan7 and Asma Bibi8

...ucial to find a suitable dose of N and S for the oil crops, so keeping in view this experiment was designed in RCB design with 4 replications (each has one control plot) in research area of agriculture university Peshawar. Two factor were studied in this experiment i.e. 5 N doses (40, 80, 120, 160, 200 kg ha-1) and 3 S doses (20, 40, 60 kg ha-1). Urea was used as source of Nitrogen and amm...

Nimra Altaf1, Muhammad Arshad1, Muhammad Zeeshan Majeed1, Muhammad Irfan Ullah1*, Hamza Latif1, Muhammad Zeeshan1, Gulfam Yousuf1 and Muhammad Afzal2

...s with time. Recommended dose of chlorantraniliprole (50 ml/100 litre water) insecticide showed 71.0% mortality of FAW on 5th day, which increased up to 82.0% on the 7th day after application of treatments. No significant (P > 0.05) difference in larval mortality was observed for chlorantraniliprole (recommended dose) and neem at 100ppm on the 5th and 7th day after application. Higher concentration (100ppm) of neem showed...

Duong Thanh Hai1*, Tomas J. Acosta2, Tran Thi Minh Tu3

... preliminary experiment, doses of PF915275 (PF, 11-β hydroxysteroid dehydrogenase type 1 inhibitor) was exanimated. PF at a dose of 1000 nM (PF1000) decreased significantly the absolute conversion of Cs to Cr (p<0.05). Thus, the PF1000 was chosen for the further studies. Tissues of endometrium were collected at the follicular stage (days 19-21), and exposed to Cs (300 nM) or Cs (300 nM) combined with oxytocin (OT, 10...

Mohamed E. El-Speiy1, Tarek A. Sadak1, Mohamed A. Abd-Elaal1, Ayman M. Khalifah2, Amr S. Morsy2*

...erred that an individual dose of (AG2) or its combination (AG1Zn and AG2Zn) maximizes the growth performance and economic efficiency of growing rabbits.
 
Keywords | Bioactive components, Carcass traits, Growing rabbits, Medicinal plants, Synergistic effect
...
Ch. Muhammad Rafiq1, Muhammad Rizwan1*, Bilal Atta1, Arshed Makhdoom Sabir1, Misbah Rizwan2, Muhammad Arshad3, Muhammad Zeeshan3, Hamza Latif3, Usama Bin Khalid1, Shawaiz Iqbal1
...ively. Towards different doses of nitrogen and phosphorus on N. lugens, the higher dose of nitrogen had a significant effect on N. lugens nymph survival, adult emergence and survival, while the phosphorus induced a non-significant effect. Therefore, in the absence of N. lugens resistant variety, ecological manipulation and nutrients availability could be a better strategy for short-term N. lugens management in organic rice p...
Dalia M. Aboelhassan1*, Inas S. Ghaly1, Noha E. Ibrahim2, Nermeen M. Shaffie3, Mariam G. Eshak1, Aboelfetoh M. Abdallah4, Ibrahim M. Farag1
...treatment with different doses (3.3 g/Kg., 4.2 g/kg. and 5.0 g/kg) can inhibit the upregulation of such gene expressions and enhance the histopathological changes of liver and kidney organs. These ameliorations increase by increasing the dose of FCE, through its utilization either as a protective or therapeutic agent. Using FCE as a therapeutic agent, particularly in the treatment with the highest do...

Sameena Gul1, Sayyeda Hira Hassan1, Amara Maryam1, Hafiz Abdullah Shakir1, Muhammad Khan*1, Muhammad Irfan2, Farah Rauf Shakoori1 and Javed Iqbal Qazi1

... continuous and repeated doses, cancer cells develop resistance against these chemotherapeutic drugs through multiple mechanisms including MDR1 gene expression. EGCG (Epigallocatechin-3-Gallate) is one of the major polyphenols present in the dry leaves of green tea plant (Camellia sinensis). It has been observed to potentiate the apoptosis and also inhibit cancer cell growth by affecting various signaling molecules and cell cycle regulatory proteins. Clinical ...

Xiaowei Huang1, Jinji Wang1, Zhun Yu2, Minghua Duan1* and Zhe Lin1*

...), and low, medium, high dose of ASP groups (9.0, 18.0 and 36.0 mg/mL, 2.0 mL/kg·d, intragastric gavage once a day for 14 days). On the 15th day, all other groups received 60Co γ-ray irradiation with a total dose of 4.0 Gy except the normal group. The levels of NO synthase (NOS) and NO in serum, the contents of malondialdehyde (MDA) and superoxide dismutase (SOD) in kidney of each group were detected with ELISA ...

Muhammad Hammad Fayyaz*, S. Murtaza Hassan Andrabi and Muhammad Shafiq Haider

... containing differential doses of combined antioxidants (0.5 mM GLU+ 5mM CYS, 0.5mM + 10mM CYS, 1mM GLU + 5mM CYS, 1mM GLU + 10mM CYS and Control). At post-thawing, progressive motility, plasma membrane integrity (PMI), and livability of buck spermatozoa were higher (P< 0.05) with 1mM GLU and 10mM CYS as compared to control. In the second experiment, post-thaw progressive motility, PMI, and livability were higher (P< 0.05) with 1mM GLU + 10mM CYS and 1mM...

Harpreet Kaur* and S.S. Hundal

...hworm species in all the doses of imidacloprid, indicating neurotoxicity. There was an initial increase in the GST activity followed by its decrease with the duration of exposure to imidacloprid. Imidacloprid is highly toxic to earthworm inducing physiological which may cause catabolism of enzymes. Earthworm M. posthuma was observed to be more susceptible as compared to E. eugeniae. The current study signifies that the irrational use of such insecticides could...

Ahmed A. Mohammed1, Madeha H. A. Darwish1, Eman A.A. Negm2, Ayman S. Abdel- Maguid3 

...ndicated that the 1 g/kg dose (0.5 concentration) of probiotics provided for group H was better than the low concentration of probiotics provided for group L (0.25 concentration). The study concluded that extention of the investigated probiotic (L. delbrueckii) to broiler feed can plays an important role in improving the economic and productive efficiency of poultry farms, even though it represents only a small part of the total or variable cost of the product...

Hakan Kececi1*, Yasin Ozturk2, M. Bahaeddin Dortbudak3, Seda Yakut4, Gurdal Dagoglu5 and Merve Ozturk1

... control group. A single dose of cocklebur seed extract was provided by gavage after being concentrated by 2 ml for each animal (80 mg ATR/kg) except for those in the control group, and time-dependent hepatotoxic, nephrotoxic, hematological and biochemical effects were analyzed. No histopathological change was detected in the liver and kidney tissues of the rats in the experimental groups. Both hematological and serum biochemical values (Ca, P, TBIL, ALT, AST,...

Eman A. Al-Shahari1,2, Eman R. ElBealy3, Abdelhalim A. Alkhazendar4 and Abeer A. Alm-Eldeen4*

...nclusion, quercetin at a dose of 200 mg/kg every other day for 2 weeks could improve liver function, decrease the expression of pro-apoptotic proteins p53 and bax and increase the antioxidant defense of hepatocytes in aged male rats.

...

Mehroze Amin1, Afifa Yaqub1, Qindeel Fatima1, Rabail Hassan Toor1,3 and Abdul Rauf Shakoori1,2*

...ated p53 expression in a dose-dependent manner, while the expression of interacting partners is downregulated indicating that metformin exhibits the anti-cancerous effect by regulating the p53 pathway. Altogether this study reports the effect of metformin on the expression of p53 and its interacting partners MDM2, PIRH2 and ΔNp73in breast cancer cell line MCF-7, thereby providing evidence that metformin modulates p53 pathway to exhibit its anti-cancer pr...
Afifa Yaqub1, Mehroze Amin1, Qindeel Fatima1, Rabail Hassan Toor1,3, Saira Aftab1 and Abdul Rauf Shakoori1,2*
...ession was observed in a dose-dependent manner in both cell lines with increasing UNC0642 concentrations. A dose-dependent downregulation of gene expression of proliferation marker genes (FGF-1, CCND1, and ENO2) was observed in both cell lines, whereas upregulation of tumor suppressor genes (AMPKα2 and ELL2) and apoptotic marker gene (BIM) was observed in a dose-dependent manner. Tak...

Malik Fiaz Hussain1, Atif Akbar2, Muhammad Asif1, Laraib Nisar3, Muhammad Naeem Ashiq3 and Furhan Iqbal1*

... effect of two different doses of NiO NPs on behavior of albino mice in a sex specific manner. Five weeks old albino mice (N = 48) of both sex were intraperitoneally injected with either low dose (20 mg) or high dose (50mg/ ml saline/ Kg body weight) of NiO NPs (average particle size 43 nm) for 14 days. Control groups were treated with saline solution. A series of behavioral tests were con...

Lukman Affandhy*, Muchamad Luthfi*, Yeni Widyaningrum, Dian Ratnawati, Mutia Primananda 

... hormone GnRH in various doses on the quality of semen in Ongole Crossbreed (OC) bulls. The study used 18 OC bulls with three GnRH treatments, A (one dose/5ml/animal), B (half-dose/2.5ml/animal), and C without GnRH. The GnRH was administered once by intramuscular (IM) injection. Semen collection was carried out for 16 weeks; divided into two periods, namely 8 and 16 weeks after GnRH admini...

Muhammad Jan1*, Muhammad Ashraf Sumrah1, Javed Iqbal2, Muhammad Aslam3, Rizwan Latif4, Muhammad Arif5, Muhammad Tahir Akbar6 and Hafiz Husnain Nawaz1

...roper pruning and proper dose and source of fertilizer application at a proper growth stage. As a result, OFF season crop in once year and followed by ON year crop. Alternate bearing cannot be completely controlled but it can be minimized by adopting different approaches like mechanical pruning, pruning through use of growth inhibitors, use of bio stimulants, and proper use of mineral nutrients at proper nutrient demanding growth stage and use of different vit...

Farah Rasheed1*, Ana Aslam1, Muhammad Aftab1, Ghulam Sarwar2, Raheela Naz1, Hina Nazir3, Sadia Sultana1, Amina Kalsom1, Nisa Mukhtar1, Ifra Saleem1, Qudsia Nazir1, Muhammad Arfan-ul-Haq1, Abid Niaz4, Muhammad Arif1, Aamer Sattar1, Sarfraz Hussain5 and Adnan Rafique6

...ied with the recommended dose of nitrogen, phosphorus and potassium was taken as control. Paddy yield data were collected and rice grain was analysed for phosphorus, zinc and phytic acid contents. Findings showed that maximum paddy yield (4.80 t ha-1) was found where P and Zn were applied 120 and 5 kg ha-1 respectively with maximum P (0.55%), Zn (13.8 mg kg-1) and phytic acid (0.38%) contents. Lowest phytic acid contents (0.32%) were observed in control treatm...

Husmaini1*, Sabrina1, Firda Arlina1, Linda Suhartati1, Yozella Martilova2 

...weet potato carrier at a dose of 2 grams could affect daily egg production, egg mass and reduce the value of ration conversion, shell thickness and egg cholesterol, but doses of 1 gram and 2 grams did not affect ration consumption and egg weight. It was concluded that the administration of the best LAB probiotics Lactococcus plantarum and Pediococcus pentasaceus with a dose of 2 grams.

Fengbin Jin1, Xin Liu2 and Yanqiu Yue3*

... the efficacy of 0.25 mg dose of epinephrine as a low-dose on the severe asthma. A total of 114 patients with severe asthma of hospital were selected between December 2017 and February 2020 as the subjects of this study and divided into the observation group and the control group randomly. Patients in the control group received the regular treatment, while those in the observation group received the treatment by low-

Reem M. Ramadan1, Fady Sayed Youssef2, Gehad Genidy Mohamed3, Sameh Hamed Ismail4, M.M. El-Bahy1, Shimaa Abdel-Radi1* 

...ween the increase in the dose and the degree of the DNA genotoxic damage as represented by variations in the tail length (μm), percent of DNA in the tail segment, and tail moment (μm). Postmortem (PM) inspection of birds inoculated by LC90 exposed sporulated oocysts demonstrated a very slight or un-apparent reddens without thickening in the cecal wall with close relation to the normal un-infected control group. This with in contrast to the group inoculat...

Mai A Fadel1*, Ahmed M Elmahdy1, Jihan Mostafa Badr2, Mohammed AM Saleh3, Mona A.A. AbdelRahman3 

...ng used alone, in a half-dose combination, and in a full-dose combination against Escherichia coli and Salmonella enteritidis mixed infection in broiler chickens. One-hundred and five chickens were equally divided into 7 groups. Group one was used as a non-treated non-infected group (negative control). Group two was used as an infected with Escherichia coli and Salmonella enteritidis (mixed infection), non-treated group (pos...
Ahmed H. Massoud1, Mohamed S. Ahmed2, Moustafa Saad-Allah1, Aly S. Derbalah1, Ashraf Albrakati3* and Ehab Kotb Elmahallawy4*
...ure to repeated low oral doses of malathion, metalaxyl and cymoxanil pesticides on male rats. Results of the present study demonstrated that low doses of malathion, metalaxyl and cymoxanil pesticides was asymptomatic and mostly showed insignificant histopathological changes in treated rats. The observed values of biochemical enzymes with these low-doses were near to the control ones, where...

Habib Ullah Habib1, Malik Muhammad Akram2, Mujahid Ali1*, Tahir Mehmood3, Muhammad Manzoor4, Maqsood Ahmad3, Hasseb Ahsan1, Muhammad Mazhar Iqbal3, Malik Abdul Rehman5, Muhammad Mohsan1 and Ahsan Mohyo ud Din6 

...% of percent recommended dose of fertilizer) of NPK were studied by using soluble fertilizers. Fertigation was applied through drip irrigation according to the schedule derived through Crop Watt. Kinnow plants showed significant results regarding plant canopy, plant height, the average weight of fruits, the weight of large size fruits, the weight of medium size, the weight of small size fruits, number of fruits per plant, number of small fruits per plant, numb...

Qurban Ali1, Habib-ur-Rehman2, Muhammad Abdullah3, Asad Aslam1*, Muti Ullah4, Ali Sher5, Muhammad Faheem Akhtar1, Humaira Malik1, Muhammad Umar Qasim1, Muhammad Yasir6, Ijaz Haider1, Tamsila Nazir1 and Muhammad Jawad Saleem1

...rtellus(S.). Recommended dose rates of all the insecticides were applied. Results of mean percentcropinfestation showed that the highest infestation (40.51 %) was observed in the control plot while the lowermost (5.23 %) was recorded in Chlorpyriphos 40% EC treated plot, being the most effective among all. In the case of mean reduction data over control, the highest reduction in plant infestation (96.08%) and no of dead hearts (93.65%) was noticed inthecase of...

Ashira Manzoor1, Imran Ahmad Khan1,2*, Muqadas Sadiq3, Muhammad Omer Iqbal4 and Shaukat Hussain Munawar5

...ced myocardial damage in dose-dependent manner. The cardiac tissues showed marked improvement in extract treated groups as compared to doxorubicin treated group. This research indicates that the hydro alcoholic leaf extract of C. colocynthis have exceptional cardio protective potential as compared to toxicity induced by DOX. As a result, it could be used as an alternative medicine for the treatment of cardiovascular disorders.

...

Siriporn Namted, Kanokporn Poungpong, Wiriya Loongyai, Choawit Rakangthong, Chaiyapoom Bunchasak* 

...ydrolysis) and differing doses/responses. In a feed additive, the components of the cell wall (β-glucan and mannan-oligosaccharides) and some of their cellular metabolites are key beneficial factors in promoting the growth performance, immunological response, gut morphology, gut microbiota, and feed consumption of pigs.

Keywords | Yeast extract, Yeast cell wall, Performance, Immune, Pig  

...

Jiahua Peng1,2, Shiyao Hua3* and Qian Wu4

...oup, the DHEA group (low dose, 15 μg/kg/d) and the DHEA group (high dose, 30 μg/kg/d). DHEA subcutaneous injection was used to construct the PCOS model of the polycystic ovary syndrome (PCOS) model of rats. The general condition of rats (body weight, ovary weight) and ovarian tissue pathology changes were observed. The changes in content of testosterone (T), follicle-stimulating hormone (FSH) and luteinizing hormone (L...

Saydat Saad Abd El-Megeed1, Walaa Yehia El-Sayed1*, Tarek Khamis2 

...mogenate which is also a dose- and time-dependent manner. Thus, the study has demonstrated that the combination of Empagliflozin and ZnO NPs could be a promising therapy to alleviate the progression of diabetes.

Keywords | ZnO nanoparticles; Diabetes mellitus; Glucagon-like peptide-1; Gene expression; Hedgehog signaling pathway. 

...

Sehrish Ashraaf1, Hafiz Muhammad Tahir1*, Chand Raza1, Ayesha Muzamil1, Farman Ahmad Chaudhary2, Muhammad Summer1 and Aamir Ali1

...sericin and curcumin was dose dependent. The highest concentrations of sericin (0.09 mg/ml) and curcumin (3%) reversed the blood parameters close to the normal. The hematological studies for this mixture formulation of sericin 0.09 mg/ml sericin and 3% curcumin were reported for the first time and they significantly (p< 0.05) balanced all blood cells. 
 
Novelty Statement | This research article...

Sehrish Ashraaf1, Hafiz Muhammad Tahir1*, Chand Raza1, Ayesha Muzamil1, Farman Ahmad Chaudhary2, Muhammad Summer1 and Aamir Ali1

...sericin and curcumin was dose dependent. The highest concentrations of sericin (0.09 mg/ml) and curcumin (3%) reversed the blood parameters close to the normal. The hematological studies for this mixture formulation of sericin 0.09 mg/ml sericin and 3% curcumin were reported for the first time and they significantly (p< 0.05) balanced all blood cells. 
 
Novelty Statement | This research article...

Mingqing Wang1 and Xiaojuan Chen2,*

... combined with different doses of glucocorticoid methylprednisolone positively improve the pH value of patients with acidosis, increase the partial pressure of oxygen and lower the partial pressure of carbon dioxide (P<0.05 in all three groups). Methylprednisolone at 40mg every 12 h proved better than other doses (p<0.05). The average length of stay was (12.5±3.0) days, the complication rate was 6.67%, and the o...

K. H. El-Kholy1*, Enayat Hassan Abo El-Azayem2, Safaa Ataya Barakat2, Mona Gamel Mohamed3, Sara H. M. Hassab1 

...sion, especially in high dose “G4”, lead to significant (P≤0.05) reduction in bacteria count of E. coli and clostridium spp. and increased total bacterial count in caecal content. The caecal NH3 concentration significantly (P≤0.05) decreased when the dietary AV level increased. Haematological, plasma biochemical and antioxidant enzymes (SOD, GPx and CAT) were significantly elevated (P≤0.05) by the highest dietary AV inclusion (G4). The add...

Reda Hassan*, Bahaa Abou-shehema, Sherif Zayed, Micheal Gorgy, Shama Morsy, El-Sayed Abu El-Hassan, Mahmoud El-Gbaly, Hanaa Basuony, Ebtehal Hassan 

...re, AFB1 toxicity at 1mg dose significantly (P<0.05) increased creatinine, uric acid concentrations, alanine aminotransferase (ALT), aspartate aminotransferase (AST) activities and significantly (P<0.05) reduced the antibody titer against sheep red blood cells (SRBC), total protein, albumin values in broilers serum compared with ngative control. Aflatoxins supplementation significantly (P<0.05) increased malondialdehyde values in liver and significant...

Rezqita Putri Pitaloka1, Kartiawati Alipin1, Mas Rizky A.A Syamsunarno2, Gemilang Lara Utama3, Ramdan Panigoro2, Ratu Safitri1* 

...howed that the effective dose was the combination of 75 mg/kg BW DFP and 50 mg/kg BW SWEE as an adjuvant, while 200mg/kg BW SWEE can be used as a substitute for chelators, especially in the heart. The decrease in serum and organ iron levels due to the combination of DFP and SWEE showed their ability to act as an adjuvant and substitute for chelators.

Keywords | Adjuvant, Deferiprone, Iron levels, Sappan wood ethanol extract, Substitute. 

...

Noor-us-Sabah1*, Mukkram Ali Tahir1, Tayyab Boota1, Muhammad Luqman2, Ghulam Sarwar1, Amir Aziz1 and Ameer Hamza1 

...rtilizers in recommended dose NPK (150: 100: 110 kg ha-1), T3 as FYM (10 t ha-1) in addition to chemical NPK application, T4 as poultry manure (10 t ha-1) also named as compost-I in addition to chemical NPK application and T5 as press mud or compost II (10 t ha-1) in addition to recommended chemical NPK application. The results had demonstrated that all the organic and chemical fertilizers increased plant growth and quality attributes (plant height, plant stem...

Emtiaz Ibrahim Ghoniem, Gaber Mamdouh Abdelgalil, Amira Farouk Gad* and El-Sayed Hassan Eshra

 
...cated with two sublethal doses of CuSO4 (0.25 and 0.5 of LD50) after 24, 48 and 72 h were examined. The results indicated that the LD50 values of CuSO4 were 166.5, 92.59 and 70.63 µg/g b.w for 24, 48 and 72 h, respectively. The biochemical effects of CuSO4 led to a significant increment of AChE activities in treated snails after all tested times. While the tested compound inhibited ALP activities in all treated animal groups. AST and ALT activities in tr...

Saima Rubab1,3*, Ghazala H Rizwani2, Arjumand Iqbal Durrani3, Iram Liaqat4*, Urooj Zafar5, Mahjabeen6, Farah Batool7, Noor-E- Seher3, Naveera Younas3 and Ayesha Sadiqa8

...lts both at low and high doses. Likewise, both seed and leaf showed significant analgesic effects. However, compared to seed extract which showed highly significant (p < 0.001) increase in concentration dependent manner, leaf extract displayed highly significant results even at low dose with better results at high dose compared with standard.

...
Huma Abbas1*, Nazir Javed1, Muhammad Kamran2, Sajid Aleem Khan1, Abdul Jabbar1, Akhtar Hameed1, Hira Abbas3, Azhar Iqbal2 and Ehetisham-ul-Haq2
...tin at their recommended doses and inoculated with 500 freshly hatched juveniles (J2s) of M. incognita. Data were recorded after 7, 14, 21 and 28 days to check the invasion and development stages. All the treatments significantly reduced invasion and subsequent development of M. incognita in roots. Different application methods regarding protective and curative were used to test the efficacy of Cartap, Virtako, Cure and Azadirachtin. Results revealed that Prot...

Salma Bessalah1, Samira Jebahi2, Asim Faraz3*, Amel Raoufi2, Cem Tırınk4, Walid Dridi2, Mahmoud Daouad2, Hassib Keskes5, Touhami Khorchani1, Khaled Farah2, Abdul Waheed3 and Mohamed Hammadi1

...r γ-irradiation at doses from 5 to 30 kGy were reported by physico-chemical techniques such as electron paramagnetic resonance (EPR), Fourier transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD) for the first time. Results revealed that gelatin yield increased significantly (P<0.05) as the extraction temperature and time increased (19.71%) at 70°C for 12 h. EPR spectroscopy demonstrated that 10 kGy of radiation-induced the decomposit...

Atilla Yıldız* and Ayse Kılıç

...onsisted of 12 cows. Two doses of prostaglandin F2 alpha were administered intramuscularly 11 days apart. Treatment group was given 500 mg resveratrol once daily from the administration of the second prostaglandin F2alpha to the insemination day. Control group did not receive resveratrol supplement. The mean erythrocyte GSH-Px levels were nearly similar in both groups before resveratrol therapy. However, at post-therapy, mean GSH-Px concentrations in group T w...

A. M. Rahoo1, 2, †, T. Mukhtar3, B. A. Bughio4, S. R. Gowen1 and R. K. Rahoo5

...he effect of inoculation doses of S. affine and
extraction methods was investigated on the production of IJ in Galleria mellonella. There was significantly greater
emergence of IJ of S. affine from the Galleria mellonella using White traps than with modified Baermann extraction
trays. In Baermann extraction trays, the maximum emergence of IJ of S. affine was observed at an inoculation

K. Taimoor1† and F. Shahina2

...y and pot experiments at doses of 0.5g/lit water (0.5% w/v), 1.0g/lit water (1% w/v), 1.5g/lit water (1.5%
w/v), 2g/lit water (2% w/v), 2.5g/lit water (2.5% w/v) and 3.0g/lit water (3% w/v). Zatoria multiflora, Achillea
santolina, Ferula oopoda and Nepeta cateria showed more efficacies as compared to other medicinal and aromatic
plants both in laboratory and pot experiments. During laboratory experiments highest mortality (1...

R.R. Arain, R.N. Syed, A.Q. Rajput, M.A. Khanzada1, N.A. Rajput and A.M. Lodhi1

...to plants. However, high dose of furadan became phytotoxic and plant
growth was checked together with a number of galls. While, higher doses of neem extract and T. harzianum
improved the plant growth. The combined applications of neem extract, furadan and T. harzianum were more
effective than alone. In combined application also, the higher dose of furada...

A.A. Anter, A.W. Amin†, A.H. Ashoub* and A.S. El-Nuby*

...
Reiterative doses post-inoculation were improved the efficacy of single dose revealed that three doses
remained more effective than one or two. While, differences between two or three time doses wer e
insignificant. On the other hand, plant fitness was slightly impaired with third dose<...

Ahmad Abrar Khan1*, Ghulam Qadar1, Asif Ali Abro2 and Muhammad Awais3

...s along-with recommended dose and treatments must be defined by the recommendations of agriculture experts instead of fellow farmers and agrovet sellers. Trainings, workshops and field activities should be organized regarding improved farm management practices especially on the aspect of insects/pests management to minimize the yield losses. 

...

Asmatullah Kaka1*, Wahid Haron2, Nurhusien Yimer3, Abdullah Channo1, Ali Raza Jahejo2, Mahdi Ebrahimi3, Dildar Hussain Kalhoro4 

...ed and control groups. A dose-dependent increase (P<0.05) was found in C22:6n-3, DHA and n-3PUFA as compared to control group. In conclusion, supplementation of 10 ng/ml of DHA in a Tris-based extender improves the frozen-thawed quality of bull semen.

Keywords | Docosahexaenoic acid DHA, Fertility, Freezing, Tris-Extender, Spermatozoa. 

...

Zubair Aslam1, Ali Ahmad1*, Korkmaz Bellitürk2, Hira Kanwal1, Muhammad Asif1 and Ehsan Ullah1

...out to optimize the best dose of fertilizers for tomato crop at Student Research Farm, Department of Agronomy, Faculty of Agriculture, University of Agriculture, Faisalabad in a tunnel under field conditions. The experiment had five treatments in which the mineral (NP) fertilizer, simple compost, earthworm’s excreta-based vermicompost and vermi-tea were alone and combined in different proportions as (T0: control (recommended fertilizers), T1: 100% simple...

Owolabi Olutunmise Victoria1*, Saka Olusola Stephen2, Olashinde Oluwaseun Ruth1, Alli Smith Yemisi Rufina3

...istered orally in graded doses to the diabetic animals (50mg/kg, 100mg/kg, 200mg/kg and 400mg/kg bodyweight) and glibenclamide. Results showed a significant reduction of blood glucose level in the extract-treated rats (p <0.5) especially at 200 mg/kg and 400 mg/kg body weight. Samples were obtained for some biochemical (parameters) related to oxidant and antioxidants such as antioxidant enzymes, Reduced glutathione (GSH) activity, Superoxide dismutase (SOD)...

Bashir Ahmad1*, Ali Muhammad Yousafzai2, Waqar Ali1, Ikram Ilahi1, Farman Ullah3, Saeed Ahmad1, Ayaz Ali Khan1, Umair Ahmad2 and Hafsa Maria2

...act scavenged at various doses was used to determine its antioxidant capacity. There were five groups each of which contains eight rabbits as experimental animals. These groups were, group A (control animals), group B (intoxicated animals), group C (Animals treated with standard drug), group D and group E (extract was given at doses of 100 and 300 mg/kg body weight after paracetamol intoxication) retrospectively. The results...

Aamir Mushtaq1*, Fatima Habib2, Umar Farooq Gohar3, Abdul Malik4 and Mobasher Ahmad2

...istration of single oral doses (4, 5, 6, 7 and 8 g/Kg/po) respectively, to individual groups (n=5) and after that the behavioral changes were observed. To find the chronic toxicity, the animals were divided in three groups (n=6) which were orally administered with normal saline, P. anisum methanolic extract 400 mg/Kg, and 800 mg/Kg respectively for three months. The results of acute toxicity study represented the LD50, value as 4.1 g/Kg/po in albino mice and i...

A. Yu. Aliev1*, A.A., Aliev1, A.M. Musaev1, M.Z. Magomedov2 

...administer Dioxinor at a dose of 0.1 ml / kg body weight, in twice a day until complete recovery and oxytocin, at a dose of 5 units in once a day on of the first 2 days of treatment, and also of carry out arrogant novocaine blockade according to D.D. Logvinov, twice 0.25% novocaine of solution, at a dose of 0.5 ml / kg body weight. In the experimental group, where the complex antimicrobial...

Zarema Alimsultanova Magomedova1*, Kheda Khalitovna Dadaeva1, Roza Said-Akhmedovna Zakhkieva1, Khasan Khamitovich Shakhbiev1, Boris Kazievich Laipanov2 

...ableted Helmicide F at a dose of 70 mg / kg of body weight had EE and IE - 100%, Fenbental 50% powder 50% at a dose of 75.0 mg / kg body weight on ADV, once had EE and IE - 100%. The new composition Mebentfen 50% powder at a dose of 70 mg / kg of live weight, once mixed with minced meat, is highly effective (EE and IE - 100%) in experiments and is recommended for the treatment and preventi...
Seyedmohammad Karimi1, Mohammad Darvishi2*, Mohammad Barati3, Ramin Hamidi Frahani4, Mohammad Hassan Kazemi5
...r duration and different doses are recommended.
 
Keywords | Remdesivir, Melatonin, N-acetyl cysteine, Liver injury, Covid-19
...

Khasan Khamidovich Shakhbiev1*, Saidkhamzat Saidmagomedovich Abumuslimov1, Larisa. Vakhaevna Taramova1, Islam Khasanovich Shakhbiev1, Svetlana Aleksandrovna Shemyakova2 

...tion azitroprazifen at a dose of 20 mg / kg body weight with ground beef of in echinococcosis young of dogs complicated by streptococcosis was high in our experience. In all 100% of the experimental dogs, on the 7th day after treatment, there was a complete absence in feces of eggs of E. granulosus and bacteria of the genus Streptococcus and an improvement in the physiological state of the body. In the experiments, a new complex bactericidal-anthelmintic compo...

Kainat Bibi1*, Sajjad Khan1, Zulfiqar Ali Gurmani1, Fahad Karim Awan1 and Sajid Ali2 

...e applied at recommended doses. Data was recorded on various morphological, yield and quality parameters. The result revealed that organically sown wheat varieties took more days to anthesis and maturity while more tillers, biological yield, grains yield and leaf area were recorded in inorganic treatments. Quality of organic produced wheat was comparatively better than inorganic wheat as more 13.67 % more crude protein and 2.41 % more crude fiber fat were reco...

A. N. Mahar, N. D. Jan†, A. Q. Mahar and S. R. Gowen

... ° C. When different dose concentration levels were tested in the sand arena, all dose concentrations resulted satisfactory mortality but a high level of dose concentration (400 IJs / ml) caused maximum insect mortality in all isolates. A similar response was observed in infectivity test when maximum percentage of IJs of both isolates of 

Shah Murad Khan1, Hamayun Khan1, Younas Muhammad1, Haq Aman Ullah1*, Muhammad Tariq Tunio2, Ali Gohar2 and Fazli Rabbani

...y 0, concurrent with two doses of PGF2-α at 8 hr. interval, GnRH-2 on day 3, followed by TAI after 16 hrs. Results showed higher estrogen (E2) and lower progesterone (P4) concentrations for MSS than POP group. Cows with higher E2 and lower P4 levels at estrus got conceived (P<0.05). Highest level of E2 was recorded in pregnant cows in POP group in comparison with MSS. The P4 concentration of pregnant cows in MSS was lowest at the time of insemination ...

Yusri Sapsuha1*, Nur Sjafani1, Suryati Tjokrodiningrat2

...istration of appropriate dose is believed to replace the role of AGP, which is currently prohibited from its use in broiler chicken feed.
 
Keywords | AGP, Broiler, Cloves, Health status, Performance
...

Dalia Zaafar1*, Heba M.A Khalil2, Soha Hassanin3, Mohamed R. Mousa4, Mona G. Khalil1 

..., Cis (5 ml/kg), Pio low dose (LD) (17.5 mg/kg), Pio high dose (HD) (30 mg/kg), Cis+Pio LD, and Cis+Pio HD. Different parameters, including behavioral, biochemical such as malondialdehyde (MDA), reduced glutathione, superoxide dismutase (SOD), tumor growth factors, and apoptotic TUNEL assay, were evaluated after three weeks in addition to Immunohistochemical analysis was done on the proliferating cell nuclear antigen (PCNA),...

MARIUM ASLAM, MUHAMMAD JAVED, FAIZA AMBREEN* & FARIHA LATIF

Caiping Duan

...andomly divided into low-dose propofol group (n=123; intravenously injected with 25 mg before angiography), high-dose propofol group (n=123; intravenously injected with 50 mg before angiography) and control group (n=123; receiving local anesthesia before angiography, subcutaneously injected with 2% lidocaine 2.5 ml at puncture point). After coronary angiography in each group, the serum nitric oxide (NO), endothelin-1 (ET-1) ...

Ahmed Ali Chandio1, Asghar Ali Kamboh1*, Nazar Ali Korejo2, Riaz Ahmed Leghari3 and Muhammad Ali Chandio4

... and gut microflora in a dose-dependent fashion thus suggested its’ inclusion in broilers diet up to 2% level.

...

Safaa Rhaimi1, Sara Brikat2, Mouloud Lamtai2*, Mohammed Ouhssine1

...ry enhancing of the safe dose of this essential oil. In this experiment, salvia officinalis essential oil was administered once by oral gavage to four groups of female Wistar rats (n=6) at three different doses; 1000, 2000 and 3000 mg/kg. During 14 days after dosing, a follow-up was carried out for the mortality, food and water consumption, body weight changing and clinical signs. Biochemical parameters and organ weight were...

Hussein Jabar Jasim1*, Amer Murhum Al-Amery2

... using ginger extract at doses of 20, 25, and 50 mg/mL with treatment times of 24, 48, and 72 hr. respectively, resulted in 100% ovicidal effectiveness.
 
Keywords | Ovicidal, Zingiber officinale extract, Fasciola spp. Eggs
...

Rafik Soliman1*, Rafik H. Sayed2, Hanan Mahmoud3, Heidy Abo El-Yazeed1, Marsell Saad1, Shaimaa Abdelall Elsaady2, Khalid Sh3 

...etermined minimal lethal dose of gamma radiation (4krad kGy/min) and the bacterial inactivation was assured using bacteriological examination. Two experiments were done; in experiment No.1, the immunizing efficacy of the prepared vaccine was evaluated in two groups of apparently normal lactating cows (4 cows /group). The first group was unvaccinated and kept as a control group all over the study while the animals in the second group were immunized with the pre...
Muhammad Rizwan1*, Bilal Atta1,  Muhammad Arshad2, Sohail Akhter3
Muhammad Tahir3, Misbah Rizwan1, Muddassir Ali1 and Arshad Makhdoon Sabir1

Shaimaa A.Tawfik2,3, EL S.T. Awad1*, Hoda O.Abu Bakr1, Amira M.Gamal-Eldeen4, Esmat Ashour2, Ismail M.Ahmed1  

...ps were injected IP at a dose of 2.5 mg/kg trice weekly to be totally 15 mg/kg for two weeks. G1 Control, G2 CSO, G3 Doxorubicin, G4 CSO/DOX. Antioxidant activity, histopathological examination, immunohistochemical analysis of CYP3A4, MRP-1, and c-MYC proteins and expression of miRNAs were assayed. Results: Findings indicated that CSO treatment led to a suppression in hepatotoxicity, nephrotoxicity and cardiotoxicity induced by DOX in male albino rats evi...

Rahma Boukarine*, Leila Hamdi and Kamel Khelili

...eated with xylene at two doses 400 and 800 mg / Kg bw and 2 combination groups REX1 and REX2 were treated with ESAE (350 mg/kg bw) combined with 400 and 800 mg/Kg xylene respectively. The results revealed that oral treatment with xylene (X1 and X2) caused hepatic and renal dysfunction, which was manifested by a significant elevation of AST, ALT, ALP, urea, uric acid and creatinine plasma levels. Additionally, a significant decrease in GSH levels and GPx activi...

Xiaowei Huang1, Chao Ma1, He Lin1, Yuchen Wang1, Yan Xu1, Guangfu Lv2* and Zhe Lin1*

...and OR400 (OR 400 mg/kg) dose groups. After the last administration, the content of corticotropin-releasing hormone (CRH), adrenocorticotrophic hormone (ACTH) and corticosterone (CORT) in serum were detected. Hematoxylin and Eosin (H&E) staining was used to observe the hippocampal histomorphological changes. The protein levels of glucocorticoid receptor (GR), mineralocorticoid receptor (MR), brain-derived neurotrophic factor (BDNF), trosine kinase B (TrkB)...

Nawfal Hammadi Jasim1, Yasmeen Jassim Mohammed2 , Jala Amir Salman Alahmed1, Majdy Faisal Majeed3* 

...thods: receiving an oral dose (2 daily MPH doses), represented by Group 1 (5 mg/kg/day in a 5% glucose solution), Group 2 received daily dosages of methylphenidate in escalating amounts (5, 8, 12, and 16 mg/kg/day in a 5% of sucrose solution), as well as Group 3 as control animals ( 5% glucose solution). Group 1 resembled the therapeutic doses administered to humans, while Group 2 simulat...

Saima Mehar1, Amtul Sami2 and Erum Iqbal3*

... the lowest administered dose of 0.25 % concentration. After 72 hours of treatment, C. cyminum (MeOH) and N. sativa (BeOH) had a non-significant difference in nematotoxic impact (90.0±10.3, 88.0±7.2 mortality %, respectively) in 1% concentration. According to decreasing order, MeOH>BuOH>Chloroform>ether >Hexane, all fractionates showed positive reactivity and potential.

...

Indira Jurinskaya1*, Tynyshtyk Kenzhebaeva2, Kairat Iskakov3, Bekzat Niyazbekov1 

...clophosphamide drug at a dose of 7 ml/kg of body weight. The results showed one-year-old goats of the Kazakh coarse-haired and Gorno-Altai downy breeds subjected to an intramuscular injection did not show a molt of down, but the output during their brushing was, respectively, 14.3 and 7.8% higher than that of the peers in control groups due to better separation of down. The down output in experimental animals partially increased and its technological qualities...

Rukhsana Anwar1*, Muhammad Usman Khalil1 and Kanwal Ashiq1,2

...ertensive rats, the test doses of the extract significantly decreased systolic blood pressure (96.75±3.9 mmHg and 104±3.8 mmHg), diastolic blood pressure (73.12±5.2 mmHg and 65.37±8.2 mmHg), mean arterial blood pressure (81±4.1 mmHg and 78.25±6.7 mmHg), and heart rate (370±33.9 beats/min and 298.25±19.1 beats/min) respectively as compared to hypertensive rats. Sub-acute study results showed that the extra...

Muhammad Waqas Yonas1,2*, Khuram Mubeen2, Muhammad Irfan3, Muhammad Ayaz Shahzad4, Mudassir Aziz2, Saad ur Rehman5 and Shoaib Zawar

...ce herbicides in reduced doses can restrict weeds growth till 40 DAS to maximize wheat productivity. 

...

Zahra Abdulameer Al-Zayadi1, Hana Kadum Shanan1, Al Salihi Karima Akool2

...ncer induced+ Sc-RE/ low dose; G7, cancer induced+ Sc-RE/ moderate dose; G8, cancer induced+ Sc-RE/ high dose). Liver and kidney samples were collected from all mice during different experiment periods, kept in 10% neutral buffered formalin, and sent for histological analysis. No abnormal histological features were seen in liver and kidney sections from the control and other mice groups be...

Munir Ahmad1, Abdul Ghaffar1, Riaz Hussain2* and Rifat Ullah Khan3*

...in groups B, C, and D at doses of 500, 1000, and 1500 µg/L in water. For histopathological and hematological examinations, blood and other visceral tissues were obtained on days 10, 20, and 30 of treatments. Different physical and behavioral disorders were noted in terms of time and concentration manners. In comparison to control fish, the hematological profile including lymphocyte, hemoglobin erythrocyte and monocyte counts, was considerably (p < 0.0...

Sarwat Yousuf1, Shaista Emad2 , Mohammad Misbah ur Rehman3, Zehra Batool4, Sara Qadeer5, Yousra Sarfaraz1, Sheeza Sheikh1, Sana Sadaf6 and Tahira Perveen1,*

...with lemon peel oil at a dose of 0.7, 1.4, 2.1, 2.7, 3.5 g/kg for 14 days. Results showed that lemon peel oil at low doses has antidepressant and anxiolytic activity. Muscular strength was also improved at low doses. The brain antioxidant defense enzymes were also enhanced whereas plasma corticosterone levels were significantly decreased following the administration of a low

Antonius Agung Wiono1, Maria Elizabeth Nana Wijayanti1, Dhika Yonika Primacitra1, Trioso Purnawarman2, Andriyanto3, Aulia Andi Mustika3, Amaq Fadholly3* 

...sis. Results: PyhtoceeTM dose 200 g/ton of feed had higher final weight and body weight gain with lower FCR, increase the valuesof RBC, HTC, lymphocytes, HDL and lowest mortality ratesamong the groups. While, the triglycerides, cholesterol, LDL and cortisolvalues were lower compared to others group, also the data of SGPT and SGOT values were similar to normal control. Conclusion: The data showed that PhytoceeTM 200 g/ton of feed had the best results among the ...
Mahroze Fatima1*, Syed Zakir Hussain Shah2, Muhammad Afzal3, Muhammad Bilal4 and Ayesha Khizar1
...ties, however the higher doses did not outperform the moderate doses. Saturated fatty acids and monoenes were more in fish fed the control diet compared to vitamin E fed fish. The percentages of 18:3n-6 (linolenic acid), 20:5n-3 (eicosapentaenoic acid), 22:5n-3 (docosapentaenoic acid), 22:6n-3 (docosahexaenoic acid), total n-3 and n-6 polyunsaturated fatty acids were found higher in diets enriched with vitamin E than in the ...

Trinil Susilawati1*, Aulia Puspita Anugra Yekti1, Amir Firdaus2, Dinda Ayu Damayanti2, Rizki Prafitri1, Nanang Febrianto1, Kuswati1, Achadiah Rachmawati1, Sri Wahjuningsih1, Nurul Isnaini1 

...ed. The method of Double-dose AI can highly improve the success of AI. The materials used were 160 cows divided into 80 cows inseminated by a single dose and 80 cows inseminated with a double dose. There were two treatments in this research; T1 was AI single dose at the 8th hour after estrus onset, while T2 AI double dose<...

Muhammad Hasnain1*, Muhammad Hussnain Babar1, Ghulam Sarwar1, Muhammad Kashif Nadeem2, Sajid Nadeem3, Muhammad Akram4, Ali Raza4, Mussurrat Hussain5, Qaisar Abbas5 and Muhammad Shahid4

...tices. Field recommended dose of these acaricides were used knapsack sprayer. Results showed a significant mite reductionby allacaricides as compared to control. Among the tested acaricides, hexythiazon 10% WP (Nissorun) gave the highest reduction of mites (i.e., 41.42, 55.56 and 37.90%) after 3, 5, and 7 days of first spray, respectively. Similarly, after second spray, hexythiazon 10% WP (Nissorun) again gave maximum reduction (i.e., 41.65, 39.33 and 16.40%) ...

Nguyen Thi Anh Thu1*, Ly Thi Thu Lan1, Nguyen Thuy Linh1, Chau Cong Dang1, Nguyen Hoang Phuc1, Tran Dinh Tuan1, Nguyen Trong Ngu2 

...iments, BC was used at a dose of 109 PFU/mL, and SE was used at 108,2 CFU/mL. In the protective experiment, 1-day-old chicks were arranged in CD) control diet; BC+S) CD + 1 mL BC (gavaged at days 1, 2, 3, 4, 5) + 1 mL SE (gavaged at day 3); S) CD + 1 mL SE (gavaged at day 3); S+A) CD + 1 mL SE (gavaged at day 3) + gentamicin at 1 g/4 L water (gavaged at days 1, 2, 3, 4, 5). In therapeutic experiment, 2-days-old chicks were arranged in CD; BC+S) CD + 1 mL BC (g...

Lianci He1, Dingxi Bai2, Chenxi Wu2, Yizhu Zhong2, Shi Chen2, Xinru Bao2, Jing Gao2*, Chaoming Hou2*

...control group (CON), low dose Shenxian Congee group (SXC-L), medium dose Shenxian Congee group (SXC-M), high dose Shenxian Congee group (SXC-M), fluoxetine hydrochloride group (influenza group, FLU) and chronic fatigue syndrome (CFS) group. In addition to the CON group, the remaining five groups established CFS rat models through forced swimming test and chronic restraint stress. After 28 ...

Ertika Fitri Lisnanti1,4, Widya Paramita Lokapirnasari2*, Eka Pramyrtha Hestianah3, Mohammad Anam Al Arif2, Zein Ahmad Baihaqi4,5 

...abane leaf extract at a dose of 4ml/litre, P2: Drinking water plus Marsh fleabane leaf extract at a dose of 6ml/litre, P3: drinking water added Marsh fleabane leaf extract with a dose of 8ml/litre, P4: Drinking water plus marsh fleabane leaf water extract with a dose of 10ml/litre. Data were analyzed using analysis of variance (ANOVA), if the results ...

Wizna1, Rusfidra2, Robi Amizar3, Romi Andika1, Muhammad Haikal1, Zurmiati1*

...e times. Factor A is the dose of B. amyloliquefaciens (3, 4, and 5%), and factor B is the fermentation time (3, 4, and 5 days). The total colony count of Bacillus sp., water content, dry matter, crude protein, crude fiber, crude fat, calcium, and phosphorus were measured. The dose of B. amyloliquefaciens and fermentation time significantly effect (p<0.05) the total colony count of Bacillus sp. in the fermented product, bu...

Khalid M. Al-Syaad1,2

...ministered the treatment doses orally by gavage for 28 days. Control, treated with a physiological solution (5.0 ml/rat). CC-treated group, treated with CC 15 mg/kg/bw. CC+propolis, treated with CC 15 mg/kg/bw + 30 mg/kg/bw propolis. Propolis-treated group, treated with 30 mg/kg/bw propolis. Blood samples were collected for biochemical analysis, and tissue samples (liver, kidney, and testes) were collected for histopathological examination. The results showed ...

Rusul Adnan Dawood, Hasan F.K. Alghetaa*

...Cl2 with RES in the same doses mentioned earlier. All treatments lasted for four weeks. At the termination of the experiment, blood samples were collected to evaluate the renal function as well as to evaluate the redox system activity. Furthermore, peritoneal exudate was collected to determine the population of infiltrating cells by using trypan blue dye. Analyzed data revealed that there was renal dysfunction represented by significant (P<0.05) increase in...

Bing Yan1, Meng Meng Zhang2, Xi Chen2, Yongming Li2*, Muhammad Khan3* and Tonghui Ma1*

... glioblastoma cells in a dose-dependent manner. Further mechanistic study showed that ALT inhibits glioma SCLP and tumor growth through repression of EGFR/MOB1/LATS1/YAP signaling pathway. These findings were further validated using in vivo xenograft mouse model. Taken together, the data provides convincing evidence of ALT-mediated inhibition of glioma SCLP and tumor growth via repression of EGFR/MOB1/LATS1/YAP pathway and suggests ALT as a promising therapeut...

Tahir Rasool Qamar1, Sanaullah Iqbal1*, Muhammad Nasir1 and Habib-ur- Rehman2

...dihydrochloride (DMH) at dose of 40 mg/kg body weight, twice a week for 2 weeks. After DHM injections, chicory powder treatments were started to group G3 as well and group G2 was DHM control group receiving only basal diet while G1 was normal control group. The amount of chicory roots powder given was 5% w/w mixed in basal diet. It was observed that group G4 showed better results overall. Enzymatic activities of pathogenic bacteria were lowest in this group an...

Xiaowei Huang, Yajie Wang, Jia Zhou, Junxiu Liu, Zhe Lin and Ruili Li*

...G high-, medium- and low-dose (SBG-H, SBG-M, SBG-L) groups. After 21 days of intervention, the changes of thymus and spleen indexs were compared, the levels of white blood cell (WBC), red blood cell (RBC), hemoglobin (Hb), hematocrit (HCT) and platelet count (PLT) in peripheral blood were detected, and the changes of hemorheology were observed. Serum levels of tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), nitric oxide (NO), superoxide dism...

Sajida Batool, Iqra Ashraf, Shafaat Yar Khan, Sitara Shameem* and Breha Kazmi

...ls in time-dependent and dose-dependent manner. These findings are suggesting the immunomodulatory potential of methanolic leaf extract obtained from C. procera that together with its other therapeutic properties can be used towards modulating the immune response.

...

Omar Berkani1*, Souheila Slimani2, Nora Sakhraoui3 and Cherif Abdennour1

...the toxic impacts of two doses of cypermethrin (CYP) on the seasonal reproduction of domestic males pigeons (Columba livia domestica) subjected to a long photoperiod (19L: 05D). Therefore, thirty pigeons were divided equally into six groups; group C used as a control, group PO used as a positive control that treated by PO (300 mg/k b.w/day), CYP1 and CYP2 groups were respectively treated by 10 and 20 mg/Kg b.w/day, in addition to CYP1+PO and CYP2+PO groups. Al...

Fatimah A. Al-Saeed 

...p was exposed to Cd in a dose of 15 mg/kg b.w. The third group was treated with olive leaves extract (600 mg/kg b.w.) and exposed to Cd. The fourth group was treated with olive leaves extract (600 mg/kg b.w.) only. At the end of the experimental period, blood samples were collected and analyzed. The obtained results showed that the levels of selected blood biochemical parameters (ALT, AST, ALP, total bilirubin, creatinine (Cr), BUN, uric acid, MDA, IL-6 and TN...

Yunilas1*, Muheri Indra Aja Nasution2, Edhy Mirwandhono1, Adi Fathul Qohar3 

...ns. Factor I was various doses of organic acid (3%, 6%, 9%), and Factor II was different fermentation times (5 d, 10 d, 15 d). The treatment had a significant effect (P<0.05) on color, odor, texture, and total titrated acid. In addition, crude protein, nitrogen, crude fat, and ash had no significant effect (P>0.05). The treatment had a very significant effect (P<0.01) on chitin and pH. There is an interaction between organic acid dosage and fermentati...

Salma Jameel Askar 

...ch: G1, which received a dose of distilled water as a negative control; G2, which received a dose of meloxicam at 1.3 mg/kg.BW was a positive control, and G3 received a dose of meloxicam and beetroots ethanolic extract. Each animal received a single oral dosage of (0.1ml/100gm ) B.W. for six weeks. Red blood cells count, platelets counts, packed cell volume (PCV) percentages, and hemoglobi...

Swagata Das Gupta1, Majharul Islam1, Towhida Kamal2,Md. Rayhan Faruque3,Md. Shohel Al Faruk4* 

... with metronidazole at a dose of 20 mg/kg body weight, and the farmer was also advised on the hygienic management of his farm. After careful treatment, all the clinically affected pigeons get cured within three days. 

...

Saloua Ziani1*, Khalid Sohaib2 , Youssef Lhor3, Ikhlass El Berbri4, And Ouafaa Fassi Fihri4  

... dog receiving a booster dose is better immunized than a dog receiving a single dose. On the other hand, the time interval between the last vaccination and the time of sampling also affected the titer. The longer the interval, the lower the titer measured, and this effect becomes more pronounced when the interval exceeds 60 days. The sex did not appear to affect the rabies antibody titer. Many factors influence the antibody ...

Aeni Nurlatifah1, Anita Hafid1, Pradita Iustia Sitaresmi1, Santoso Santoso1, Rahma Isatirna Anwar1, Mohammad Firdaus Hudaya1, Diana Andrianita Kusumaningrum1, Nurul Azizah1, Dimar Sari Wahyuni1, Herdis Herdis1, Florentina Bety Indah Lupitasari1, Desiana Ade Mahari1, Muhammad Rizal2

...scorbic acid as NEZ at a dose of 20 mg/100 ml into the egg yolk tris extender resulted in the greatest preservation of ram sperm quality (P<0.05), such as motility and viability. Hence, the addition of catalase as EZ at a dose of 50 mg/100 ml to the egg yolk tris extender resulted in the highest (P<0.05) percentage of motility, percentage of live spermatozoa, and intact plasma membrane. The NEZ group showed better resu...

Raed Hussein Salih Rabee1, Yahya Sabah Abdulameer1, Walla Farhan Obed1, Noor R Abady1, Adnan Mansour Jasim1*, Firas Hussein Albawi1, Mohammed Jasim Jawad2, Ahmed Samir Abukhomra3

...ulated with E. coli at a dose of 0.5 ml containing 6x108 CFU/ml of E. coli. T2: The chickens in this group were orally inoculated with E. coli at a dose of 0.5 ml containing 6x108 CFU/ml of E. coli and were treated with enrofloxacin at a dose of 12.5 mg/kg orally through drinking water. T3 group: The chickens in this group were orally inoculated with E. coli at a d...

Haneen Imad Al-Sultani1*, Ahmed Obaid Hussain1, Hazar Shakir Saleh2 

... mg/kg rosuvastatin. The dose was continued for 60 days in a once-daily dosing regimen. After the end of the experiment, chemical analyses were performed for kidney function, including cystatin C and vitamin D3. Then, the rats were dissected, and kidney tissues were taken for histological study. Male rats treated with rosuvastatin showed an elevated cystatin C level and increased vitamin D3. At the same time, the results of the microscopic examination sho...

Md. Ariful Alam1, Mst. Misrat Masuma Parvez1, Md. Salauddin2*, Rakibul Islam1 and Md. Bazlar Rashid1

... hydrochloride 20%) at a dose rate of 1g per 3 liters of drinking water for 7 days. Results showed that the body weight of T0, T1, T2 T3, and T4 group at 30 days of post-infection were 627.96 ± 1.82, 585.52 ± 2.76, 595.66 ± 2.76, 743.17 ± 3.55, 734.88 ± 2.36 gm respectively which is statistically significant (P<0.01) and highest body weight gain was recorded from T3 group treated with yeast 1.5g/kg feed. In the case of hem...

Md. Ariful Alam1, Mst. Misrat Masuma Parvez1, Md. Salauddin2*, Rakibul Islam1 and Md. Bazlar Rashid1

... hydrochloride 20%) at a dose rate of 1g per 3 liters of drinking water for 7 days. Results showed that the body weight of T0, T1, T2 T3, and T4 group at 30 days of post-infection were 627.96 ± 1.82, 585.52 ± 2.76, 595.66 ± 2.76, 743.17 ± 3.55, 734.88 ± 2.36 gm respectively which is statistically significant (P<0.01) and highest body weight gain was recorded from T3 group treated with yeast 1.5g/kg feed. In the case of hem...

Mukkram Ali Tahir1, Noor-us-Sabah1*, Muhammad Waryam Warraich1, Ghulam Sarwar1, Muhammad Aftab2, Fakhar Mujeeb3, Muhammad Zeeshan Maznoor1, Aneela Riaz4 and Sarfraz Hussain2

...t along with recommended doses of two K chemical fertilizers (SOP and MOP). After the crop was harvested, soil sampling was carried out followed by analysis in the laboratory. All collected data was statistically analyzed for interpretations. It was depicted from results that use of carbon sequestering fertilizer (press mud @ 1 %) along with commercial K fertilizer (SOP) performed superior by resulting in maximum K content in shoot (2.13 %), K content in root ...

Jasir Hakim Hidayah1,2, Yos Adi Prakoso2, Sitarina Widyarini3* 

...wice daily using various doses of calabash for seven days. On day 8, the brains were collected and processed against histopathology. The data was analyzed using SPSS version 26. The result indicated that the most efficacious dose of calabash was 2.96 mg/kg BW from the P5 group. It is supported by the minimization of infarct area in the P5 group compared to the others. Further, this dose sh...

Sara H. Zughayyar*, Amer H. Gyad 

...inistration of different doses of Prosopis farcta L. fruit ethanolic extract (300 mg/kg, 400 mg/kg, and 500 mg/kg). A comparative group received castor oil along with loperamide (2.5 mg/kg) orally. The outcomes demonstrated that after three hours, the castor oil-treated animals produced liquid feces. Enteropooling test findings revealed that castor oil generated an accumulation of water and electrolytes in the intestinal loop. Weight and volume of the intestin...

Rana Mahmood Ahmad*, Orooba M.S. Ibrahim 

...aZnONPs and piroxicam at doses 2.5 and 5 mg/kg B.W., respectively, while (Group 1) was positive control. Blood samples were obtained using cardiac puncture at three time points during the experiment: at the beginning (zero time) and on the 12th and 21st day. These samples were collected specifically for serum collection. In the present investigation, the administration of SaZnONPs to infected rats yielded noteworthy reductions in the levels of the pro-inflamma...

Zakia Panhwar1, Arfan Ahmed Gilal1*, Lubna Bashir Rajput1, Jamal-U-Ddin Hajano2, Shafique Ahmed Memon3, Naimatullah Koondhar4, Muhammad Ibrahim Kubar1

...d at 0.1, 0.5, and 1.0ml doses on the filter paper. A long glass cylinder divided into three (A, B, and C) sections, supplied with 20g cowpea seeds at ends was used in the study. Ten freshly emerged male and female C. maculatus adults were released separately in the middle of B with the help of aspirator as treated (with oil) and untreated filter were placed at A and C sections, respectively. The number of adults were counted at A and C after 24 and 48 h to ca...

Arslan Muhammad Ali Khan1, Rao Zahid Abbas1*, Zia ud Din Sindhu1, Muhammad Shahid Mahmood2

... rates of mortality in a dose-dependent manner of adult and larvae of Hyalomma spp. Egg number, egg mass, and larval hatching were also reduced significantly (p<0.05) in a dose-dependent manner. As a result, reproductive index (RI), reproductive efficiency index (REI), and nutrient index (NI) were also decreased significantly (p<0.05) in a dose-dependent manner. Similarly, A. subulat...

Ying Chen1, Chao-Zheng Li2, Zhun Yu3, Jia Zhou4, Yan Xu4, Zhe Lin4, He Lin4* and Xiao-Wei Huang4*

...), VAP high, medium, low dose (VAP 300, 200, and 100 mg/kg) groups. After 21 days of intragastric administration, the electrocardiogram (ECG) changes in each group were detected. The activities of lactate dehydrogenase (LDH) and creatine kinase-MB (CK-MB) isoenzymes in serum, and superoxide dismutase (SOD), malondialdehyde (MDA), glutathione peroxidase (GSH-Px) and catalase (CAT) in myocardial tissue were detected by ELISA. Hematoxylin and eosin (HandE) staini...
Hina Mumtaz, Muhammad Zeeshan Majeed*, Muhammad Afzal, Muhammad Arshad, Arif Mehmood and Muhammad Qasim
... application. The medium dose rate of abamectin (4000 ppm) and chlorantraniliprole (600 ppm) also showed 100% larval mortality at 48 h of application. In semi-field and field conditions, chlorantraniliprole showed 100% larval mortality at 48 h, while abamectin and chlorpyrifos showed 87–89% and 94–81% larval mortality respectively in semi-field to field conditions after 72 h of application. Overall study results demonstrate the effectiveness of chl...

Muhammad Ali Raza1*, Aneela Zameer Durrani2, Muhammad Muddassir Ali3, Tariq Usman4, Bilques Bano5, Nazia Rubab6, Syed Tasadak Mehdi7, Muhammad Wasim Iqbal8, Kumayl Hassan Akhtar9, Hira Hameed10

...p; levamisole HCL at the dose rate of 7.5 mg/kg and 3.0% oxyclozanide BP (vet), 1.5 levamisole hydrochloride BP (vet) and 0.382% cobalt sulphate in combination were administered orally to the cattle naturally infected with mixed species of gastrointestinal nematodes. The study design also included infected but un-medicated and uninfected and un-medicated controls.  Faecal egg count reduction and larval counts from coprocultures were carried out pre and po...

Dan Song1,2, Ming-Juan Ge3, Jie Li1,2, Yi Jiang1, Xiu-Mei Kong1, Jiao-Jiao Xu1, Xu Ji1,2, Rui-Xin Shi1 and Qin Zhao1,2*

...raminea ethanol extracts dose groups (10, 5 and 2.5 g/kg respectively + hypoxia), administered intragastrically once a day for 14 consecutive days. After that, multiple hypoxia experiments were conducted including soda lime normobaric hypoxia test, sodium nitrite poisoning test, isoproterenol poisoning test, and acute cerebral ischemic hypoxia test. Subsequently, the content of superoxide dismutase (SOD), malondialdehyde (MDA), and activity of total antioxidan...
Muhammad Javed Iqbal1, Farah Rauf Shakoori1*, Bushra Muneer2 and Abdul Rauf Shakoori3
...cific drug in a specific dose for a specific patient. The PI3K/AKT1/MTOR (PI3K) pathway is crucial for normal cellular processes. Several activating factors and genetic mutations, in associated genes (PIK3CA, AKT1, MTOR and PTEN), lead this pathway to function abnormally to trigger breast cancer. The mutations in these genes were explored in female patients with breast cancer. The demographic studies showed that all the patients were married, housewives with a...

Amal Hammad*, Shaaban Gadallah, Tarik Misk, Ahmed Mourad 

...e effect of low xylazine dose than vibrational acupuncture. Hence, laser acupuncture could be a promising sedative adjuvant in dogs sedated with low xylazine dose due to their poor tolerability to conventional high doses.
 

...

Oghenebrorhie M. Oghenochuko1,4*, Olubukola T. Adenubi3, Olusola L. Ajayi3, Fakilahyel M. Mshelbwala3, Johnny O. Olukunle3, Samson A. Rahman3 and Godfrey N.O. Ezeri2

...the blood parameters but dose should be considered to avoid harmful effect on liver and kidneys.

...

Usama Mahalel1, Barakat M. Alrashdi1, Ibrahim Abdel-Farid1, Sabry El-Naggar2, Mohamed Hassan3, Hassan Elgebaly1 and Diaa Massoud1,4*

...in mice at two different doses (low; 100 mg/kg BW and high; 500 mg/kg BW). The obtained results showed that CCl4 injection significantly reduced the body weights of mice and increased the relative liver weight. Treatment with M. forsskalii extract after CCl4 injection restores the weights of mice to the normal range and reduced the relative weight of the liver. Mice that were injected with CCl4 exhibited elevation in the liver enzymes; aspartate aminotransfera...

Taidong Wang1, Xiaowei Huang1, Jian Huang2, Guangfu Lv3 and Zhe Lin1*

..., model group, wild high-dose group and wild low-dose group, 6 rats in each group. Results of in vivo experiments showed that high-dose group (P<0.01) and low-dose group (P<0.01) significantly decreased body temperature in rats; high-dose group significantly decreased TNF-α, IL-1β and IL-6 levels (P<...

Amer Hakeem Chyad1, Omar S.I. Al-Janabi2*, Orooba Mohammed Saeed Ibrahim1, Najeeb Mohaamed Hussein3

...ere administered CP at a dose of 14.2 mg/kg/BW (positive control group). third party (G3). Gave only 200 mg/kg/B.W. of Chelidonium majus alcoholic extract and 14.2 mg/kg/B.W. of cyclophosphamide were administered orally via gastric tube. Fourth group (G4): These animals were administered 300 mg/kg/B.W. of Chelidonium majus L. alcoholic extract and 14.2 mg/kg/B.W. of cyclophosphamide orally via gastric tube. Five groups (G5) Animals of this group were administe...

Rana Mahmood Ahmad*, Orooba Mohammed Maeed  Ibrahim

...il’s median lethal dose (LD50) was 2225 mg/kg, which suggests that clove oil has a relatively low level of toxicity. Eighteen adults male Wistar albino rats, six months, weighing 200–250g, were used and randomly grouped as follows: Group 1 was kept as a positive control group without treatment. At the same time, Group 2 received clove oil extract orally (10 mg/kg B.W.). Group 3 received Piroxicam (5mg/kg B.W) orally. The anti-inflammatory activity ...

Turrini Yudiarti*, Sugiharto Sugiharto, Endang Widiastuti, Hanny Indrat Wahyuni, Tri Agus Sartono, Maulana Hamonangan Nasution

...reatments consisted of a dose of the fungus Monascus purpureus as a feed additive (FA). These included T0 (basal diet/control); T1 (basal diet supplemented with 0.5% FA); and T2 (basal diet supplemented with 1% FA). Each treatment was repeated five times with a total of ten chiks each pen. Feed additive was provided to chicks beginning 8 days after rearing and was mixed in with the basal diet. Water was available at all times. The data were collected from chic...
Elamien***, Mohammed; Kotob**, Nahla S.; Elsayed*, Eltayeb A.; Ragab, Yasser M. and Mourad, Fathia E.
...a cell culture infective dose 50% (CCID50) in Hep-2 Cincinnati cell line and using the Karber's Formula. All topV (type 1, 2 and 3) samples were found to be potent, within World Health Organization (WHO) normal limits. However, type-3 poliovirus in most of the bOPV (type 1 and 3) samples showed a titer lower than the WHO normal limits although all samples have at least grade Il VVMs. These data indicate that type-3 poliovirus in case of bOPV needs more investi...

Rizk, Sonia A.; El-garf, Eman M. and Talaat, Abeer A.

...hydragel and GSLS (10 mg/dose). The humeral and cellular immunoresponses were monitored in different tested groups that received the gel adjuvanted vaccine and the Alhydragel-GSLS adjuvanted vaccine. Results indicated that the higher immune responses were found in calves vaccinated with Alhydragel-GSLS adjuvanted vaccin up to 24 week while with Alhydragel alone was only up to 18 week.

...

Zein Salwa N; Abd El-khalik, Samaa; Khatab  , Eman A.A.H and Azzam4,Clara R.

...s were subjected to four doses of gamma rays; O, 100, 200 and 300 Gy from a 60Co source. Ml and M2 generations were sown at the experimental fann of the Agricultural Res. Center to induce variability in the sunflower genotypes; Giza 102 and Sakha 53, which could be resistant to TMV-S. The statistical analysis indicated significant differences among irradiation doses on plant height; all used dose

Abd Elwanis, N.D.; Abou El Khair, M.A.; Afaf H. Amin; Azab, A. and A.O. Abd El Rahman

...chickens using different doses and estimation of the humoral immune response using the hemagglutination inhibition (HI) test. The vaccine provided a faster and more reliable • immune response against the H5N2 viral antigen after immunizing 3 weeks old chicken with a dose of 0.3 ml/bird, inoculated subcutaneously (s/c) in the nap of the neck, was fairly enough to evoke the required level of immunity. The approach through...

Abeer, E.Mansour and Hegazi, A.Z.

... were vaccinated using a dose of I ml for sheep and goats and 2 ml for cattle, buffaloes and camels inoculated subcutaneously. It was found that both of the immune parameters were generally increased gradually to reach the highest value of cellular immunity by the 2e day, while that of neutralizing antibodies was reached by the  week to the 10th week post vaccination. It was noticed that vaccination of cattle and sheep resulted in higher and longer durati...

Manva F.M. Abdel Monem; Gihan K. Mohammed;** Sami A.M.; and Saber M.S.*

...ths old calves. The used dose was 5 log10 TCID5Janimal. The safety and potency of the vaccine was followed up as well as the duration of the immunity by ELISA and SNT through 12 months post vaccination. There was no evidence of untoward effects except slight elevation of body temperature in the calves through 14 days post vaccination. The virus was recovered from the sera of 3 calves on the 2nd  and 4th day post vaccination respectively 82,78 and 76, but ...
Eman, M. M. Soliman*; Taha, M. M.*;El-Sanousi A,;Shalaby M. S. Wasscl , Youscf Adel*
... 5th WPV. Effective doses in mice has been calculated in mice by inoculation of 5 groups of mice (10 each) with 2 doses of five fold diluted vaccine; inoculated mice have been challenged I/P with virulent RVF virus 103 to 104 mouse I/P lethal dose50(MIPLD50), it was ranged from 0.006 - 0.0007. Using the Rt-PCR to confirm the efficacy of binary  ethyleneamine as inactivator to RVF...

Abdel Razek,B.Omar*and Magda M.Sayed**

... the virus in successive doses into susceptible two calves with complete and incomplete Freund’s adjuvant. Identity tests were applied by agar gel precipitation test (AGPT) and indirect fluorescent antibody technique (IFAT). Serum neutralization test (SNT) and ELISA tests were applied for titration and evaluation of the hyperimmune sera before conjugation with fluorescent. Total protein concentration of the prepared LSDV antisera was 0.8g/dl. Separation ...

Arwa H. El -Naggar, Nirmeen G. Shafiek, and M. S. Wassel.

...t adjuvant in successive doses into susceptible guinea pigs. Serum neutralization (SNT), ELISA and indirect fluorescent assay (IFA) tests were used to evaluate the hyper immune serum Before conjugation with fluorescent. The antibody titer reach 32 by SNT and 5984 by ELISA and identified by IFA to be Bovine rota. Separation of anti B. Rota immunoglobulins IgG "were done using activated Sepharose 4B followed by conjugation with fluorescein isothiocyanate at...

Sulake Fadhil Al-Zubaidi1*, Ghusoon A.A. Alneamah2, Ali Saleh Mahdi1, Abdulraheem Abduljalil Wali3

...we need to give a second dose of Aglepristone to bitch. In group II, PGF2α was injected after pus came out from the vulva, there was a rapid evacuation of pus from the uterus in comparison with group I with many side effects such as tachycardia, panting, and hypersalivation. In group III Misoprostol was used intravaginal, and evacuation of pus was seen after 1 hr. from administration, the evacuation was more than in groups I and II without side effects s...

Rizqan*, Hilda Susanty, Linda Suhartati, Azhar, Arief, Elly Roza 

...iffusion test revealed a dose-dependent inhibitory effect of the citrus fruit peel eco-enzyme against both Staphylococcus aureus and Escherichia coli. These findings underscore the antibacterial potential of the citrus fruit peel eco-enzyme solution and suggest its viability as a natural and environmentally friendly teat dipping solution for dairy cattle.
 

...

Rizkie Elvania1, Tintin Rostini1, Sakiman2, Ani Susilawati2, Emilda Adriani2, Abd Malik1*

...yolk extender at varying doses on pre-freeze and post-thawed Kalang buffalo semen. Four Kalang buffalo, aged between 6 to 7 years and weighing 500-550 kg, were involved in this investigation. Semen collection was conducted weekly a 12- week period using an artificial vagina. Lycopene was added to the skim milk-egg yolk diluent at concentrations of 1%, 2%, 3%, and 4%, while the control group received no lycopene substitution. The freshly collected semen underwe...

Zurmiati1*, Ade Trisna2, Ridho Kurniawan Rusli1, Yelsi Listiana Dewi3, Ulvi Fitri Handayani4, Wizna1 

...ayang ducks at different doses (0, 76x106, 69x108, 65x1010, 53x1012 CFU/ml), and each of these five treatment was replicated four times. Feed intake, body weight gain, feed conversion, and final body weight were the parameters studied. The results revealed that the probiotic Bacillus subtilis FNCC 0059 has a significant (p<0.05) effect on feed intake (being low in 53x1012 and 65x1010 CFU/ml), body weight, body weight gain (being high in 69x108, 65x1010 and ...

M. Tariq Mushtaq1, Faisal Manzoor1, M. Ishtiaq1*, Mirza Abdul Qayyum1, Muqarrab Ali2, M. Akram3, M. Rafiq Shahid3 and Saleem Riaz1

... at recommended and half dose of recommended for two years. In separate experiment two combinations of pyriproxyfen + imidacloprid and pyriproxyfen + matrine applied at recommended doses (RD) and 1/2 of recommended doses (HD) were applied on cotton crop against whitefly and jassid in consecutive two years. Randomized complete block design (RCBD) was used for each experiment with three repl...
Asma Ilyas1, Tanzeela Riaz 2*, Sammi Rasheed1, Uzma Ramzan1, Afsheen Munawar Butt1 and Farah Rauf Shakoori1*
Rehan Ahmed Siddiqui1,2*, Shabana Usman Simjee2,3, Nurul Kabir4, Muhammad Ateeq3,5, Kevin Joseph Jerome Borges6, Muhammad Raza Shah3 and Rahman M. Hafizur2
...ls at a relatively lower dose.

...

Sena’a M. Hussein1,2, Raffal A. Omar3* 

... which received the same dose of lidocaine carried by liposome. Pinprick and spinal reflex tests were evaluated each minute for the first five minutes following lumbosacral injection and then every five minutes until the sensory blockade disappeared. Motor activities were constantly monitored and evaluated every 30 seconds. Clinical evaluation of analgesia and motor blocks after injection revealed a complete analgesia and there was no response to deep muscle p...

Sudeb Saha1,2*, Jay Prakash Ray3, Apurbo Kumar Mondal4, Md. Irtija Ahsan5, Marina Debnath6, Dilruba Afrin7, Syed Sayeem Uddin Ahmed5, Jayanta Datta Gupta3, Nivedita Datta8, Hugo O. Toledo-Alvarado9, Haruki Kitazawa1

...s with various probiotic doses comprising T1 (15 g/d/cow), T2 (30 g/d/cow), T3 (45 g/d/cow) and control (without probiotic) in a trial of 60 days. All four groups received a total mixed diet. Cows’ body conditions and their bloods, milk yields and composition were investigated on the day of 0, 30 and 60. The results demonstrated that body conditions score, milk production, and compositions were improved in the T2 and T3 groups. Additionally, T2 and T3 gr...

Salema Lafta Hassan1*, Taghred Jabbar Humadai1, Sabrin Ibraheem Mohsin

...eurella multocida in two doses separated by two weeks. The fourth group (G4) was assigned the role of negative control at this time, the 28th day after immunization for work, serum samples were taken for passive hemagglutination test (PHA); Immunoglobulin G(IgG) detection using a chemical immunosorbent assay test. the outcomes of PHA test revealed that Folcord inhibited humoral immune response, with a considerable rise in antibody titer in the third and second...

Nasir Shah1,4, Muhammad Ibrahim1*, Zarnosh Habib2, Kalsoom3 and Zahir Shah4

...ations. However, various doses of plant extracts showed significant difference in reducing the number of oviposition, pupae developed, flies settled and post settling reproduction. There was inverse response of peach fruit flies to increasing concentration of plant extracts. Minimum significant number of fruit flies (0.58) settled after 18 h, reaching to its peak (1.73) after 42 h showing a decreasing trend subsequently. Hence, all the plants exhibited insecti...

Xiangmei Chen, Burie Bao* and Mo Degema

...d low-, medium- and high-dose camel placenta groups. A high-fat and high-sugar feed combined with intraperitoneal injection of STZ dissolved in a citric acid-sodium citrate buffer was used to establish a rat model of hyperglycaemia. Metformin hydrochloride tablets were used as a positive control to detect fasting blood glucose. The contents of glycated haemoglobin (HbALc), insulin (INS) and glucose (GLUC3) as well as the protein expression and mRNA levels of s...

Muhammad Yasin1, Azhar Abbas Khan2*, Sana Rubab2 and Sumaira Maqsood3

...n combination of highest dose of B. bassiana and DE. While, after last exposure 100% mortality was achieved at highest dose rate of B. bassiana and both doses of DEs. Contrarily, 100% mortality of Trogoderma granarium was recorded after 15 days of exposure at highest dose rate of B. bassiana and both DEs. The progeny emergence was significantly lower in ...

Pankaj Gargotra1, Judith Betsy C1*, Cheryl Antony2 and Stephen Sampath Kumar J3

...rated at three different doses in basal feed containing 23% C.P and fed to brooders for a period of 90 days. Fecundity, GSI, gonad histology, hormone (cortisol and progesterone) variations, breeding performance and growth parameters were recorded. Significant differences in the growth and breeding performance of female brooder under different treatments were noted. Among the selected vitamins, incorporation of vitamin C at 150 mg /kg of diet resulted in maximu...

Anisa Muthia Fakhira1, Madihah Madihah1, Susi Susanah2, Erick Khristian3, Ratu Safitri1*

...tervals, with cumulative doses of 10, 20, 30, 40, 50, and 60 mg/kg BW, whether the control injected with physiological sodium chloride solution. The results of the study showed that both the necrosis score in pancreatic beta cells and fasting blood glucose levels demonstrated a dose-response pattern, with higher values corresponding to increasing dosages. The ID dose starting from 20 mg/kg...

Noor A. Namaa*, Hayder A.N. Al-Zamely

...nt. T1 was given a daily dose of (500 mg/kg) of Ginseng extract, while T2 received a daily dose of 250 mg/kg of Ginseng NPs. After a 60-day experimental period, all study animals were put to sleep using chloroform to collect testis samples, which were then homogenized and measured for protein content with a focus on the SDHA proteins. The results showed that, when compared to the value of the control group, the total protein...

Diky Ramdani1*, Dwi Cipto Budinuryanto1,2, Siti Darodjah Rasad1, Novi Mayasari3, Krisna Rizki Rismawan1, Muhammad Fajryanto Solihin1, Ririn Siti Rahmatillah1

...e three different as-fed doses of PPS inclusion, comprising 0% (PPS-0), 50% (PPS-50), and 75% (PPS-75) in a PSS-based diet. This comparison aimed to evaluate lamb performances both before (Phase 1, a 30-day trial) and after (Phase 2, a 42-day trial) an anthelmintic treatment, with each phase having six replicates (n = 6). Before the anthelmintic treatment, PPS inclusion showed no significant impact (P > 0.05) on the average daily gain (ADG, g/head/day) of t...

Peixia Yu1*, Lijun Bo2 and Xueyin Song1

...and low, medium and high dose Fen groups, where in high dose group: Fen1:2μg/kg; Fen2:4μg/kg; Fen3:6μg/kg. The measured items included heart rate (HR), mean arterial pressure (MAP), left ventricular developed pressure (LVDP), ±dp/dtmax, malondialdehyde (MDA), superoxide dismutase (SOD) activity, creatine phosphokinase MB (CK-MB) and cardiac troponin-I (cTnI). The total apoptotic cardiomyocytes, B cell lymphom...

Suhad Mohmmed Alrobyrai1 , Falah Muosa Al-Rekabi2*

...amage when taken in high doses or for prolonged periods. Alpha Lipoic Acid (ALA) and Tempol are two antioxidants that have been shown to protect against various forms of oxidative stress and inflammation. This study explored the hepatoprotective effects of Alpha Lipoic Acid (ALA) and Tempol against subacutely repeated acetaminophen (APAP) exposure in a murine model. Fifty male Balb-c mice were divided into five groups. Groups received 700 mg/kg.BW of APAP and ...

Qamer J. Jadoaa, Raffal A. Omar*

...ich applied daily single dose of 2% lidocaine Hcl 2 mg/Kg. B. W. for five days post-operation (P. O.), while the group 2(diclofenac) applied 3.75% of 20mg/Kg. B. W. histopathological specimens were taken at the end of the 7th,14th, and 21th day p.o. The results revealed rapid bone regeneration improvement and development in group I compared to group II and control group. In conclusion, intra-osseous injection of 2% Lidocaine Hcl 2mg/kg BW (body weight) has a s...

Hilwah Nora1,2, Rajuddin2*, Hafizuddin3, Rachmad Suhanda4, M. Fathurrahman5

... determining the initial dose is preliminary studies based on spermatozoa quality parameters, morphology, and morphometry of testes and seminal vesicles that have never been reported. The main objective of this research is to examine the effects of curcumin on several aspects of reproduction and determine the optimal dose for using curcumin as an antifertility agent. The test animals in this study were Wistar rats (Rattus no...

Irfan Ullah1, Asad Ullah2*, Tahira Tayyeb1, Rafiq Ullah1, Muhammad Hanif1, Faiza Khan3, Imad Khan2, Raheela Taj4, Fatima Syed4, Shumaila Gul5, Muhammad Sadeeq6, Muneeb Islam7, Arsalan Khan8 and Khudija Ghani9

...diet (BD) with different doses of inorganic Selenium (Se) powder. Group-A was kept negative control provided with BD twice a day. Group-B was positive control group fed with 15mg DEX/kg twice/day. The Group-C was fed with BD+0.2mgSe+15mg DEX/kg. Similarly, Group-D was fed with BD+0.3mgSe+15mgDEX. Group-E was fed with BD+0.4mgSe+15mg DEX/kg. Two chicks were randomly slaughtered from each replicate and blood glucose level, kidney function and liver enzyme were e...

Tayfun Karatas1*, Betul Apaydın Yıldırım2 and Serkan Yıldırım3

...ever, both 50 and 100 mg doses of TLE had protective effects against CMN-induced toxicity in all the above parameters. As a result, we have shown that 100 mg of tea leaf extract is more effective in preventing harmful effects on blood biochemistry (AST and ALT), oxidative stress, immunity, apoptosis, histopathology and DNA damage caused by CMN.

...

Hongsen Xu*, Xiaoni Wang, Tie Tian, Changyu Zhao, Denghang Yu and Jun Liu

...crayfish, and the lethal dose 50% was 1.52 × 106 CFU/g crayfish. Serious histopathological changes, such as cell degeneration and necrosis, hemorrhage and inflammatory cell infiltration, were found in diseased crayfish. In conclusion, this study confirmed the pathogen of whitish muscle disease in farmed P. clarkii, and preliminarily investigated the biological characteristic, pathogenicity and drug sensitivity of this bacterium. The results of this study...

Huda S.J1*, Nasr T.M1, Mohanad A. Al-Bayati2

...me method. Anemic rabbit dosed with Nano hemosomal Cobalt-Ferrite 1/40of LD50% dose 75mg/kg Bw. Hematological parameters were analyzed in the blood samples that were collected from a rabbit. The outcomes of the hematological profile before and after hemorrhagic corrections were Hemorrhagic group RBC 5.96±0.11 x 106/mm³, WBC 6.35±1.04 x 103/mm³, PCV 33.02±6.28%, Hb 11.19 ± 0.88 g/dl and P...

Ghaith Z. Hasan Al-Askari *, Eman H. Yousif Al-Taee

...ic effects of the higher dose group (HG) (549.640 IU, i.e., 1.3741 mg/kg body weight), which represent 1/10 LD50, and the lower dose group (LG) (274.820 IU, i.e., 0.6875 mg/kg body weight), which represents 1/20 LD50 of vitamin D3. So, the objectives of this rapid review were to assess the median lethal dose (LD50) of VD in female albino rats and to assess the effects of vitamin D (VD) on ...

Zaryab Murad1*, Sobia Bibi1, Shehr e Yar Ahmad1, Mohsin Ali Khan1, Rimsha Sadaf2, Mauz ul Haq1, Umair Manan1 and Muhammad Younas2

...was applied in two split doses (@ 60:60 kg ha-1) directly after transplantation and after 4 weeks of transplantation while DAP source was used for phosphatic fertilizer (@ 90 kg ha-1). In each pot, 20 days old rice nursery was selected and 10 healthy plants were transplanted into each pot. After successful and possible growth five most perfect and healthy plants were kept for experimental work. All the pots were kept in standing water condition and the pots we...

Taghreed Jabbar Humadai*, Bushra Ibrahim AL-Kaisei

...animals exposed to toxic dose of tetrodotoxin was characterized by obvious disruption of seminiferous tubules with absence of leydig cells and congestion, in epididymis tissue the most histopathological section showed widening of intertubular distance with evidence of sperm stasis, focal hyperplasia of epididymal lining with blood vessels congestion and sever mononuclear cells infiltration in the vascular connective tissue, fibrovascular tissue with newly form...

Kashif Abdaal, Aneeza Batool, Muhammad Tariq Navid*, Saeed Ahmed, Asma Saleem Qazi, Waseem Safdar, Haidar Ali, Mobeen Ur Rashid, Somia Rafaqat 

... model, need for booster dose, route of administration, and post-administration safety and post-marketing analysis (social and economic concerns). All these steps are important for a vaccine that leads to its success in preventing infectious diseases. It is crucial to address these challenges to make safer vaccines for effective infectious disease control and prevention to save humanity. Addressing challenges in vaccination coverage and gaps is crucial for gl...

SHAGUFTA ANDLEEB1*, ASMATULLAH2, SHABANA SHAUKAT1 & SIDRA NAWAZ2

.... After 24 hours of last dose, the animals were anaesthetized torecoverliver tissues following fixation in Bouin’s fluid and processing for histological preparation using different grades of alcohol and xylene for dehydration. These tissues were later on infiltrated with paraffin wax, sectioned to size of 4μm and stained with Hematoxylin and Eosin. The histological analysis revealed that metformin could cause adverse malformations like pyknosis, necro...

SYEDA NADIA AHMAD1, MEHWISH NASIR1, AQSA NAUREEN1, SHAGUFTA ANDLEEB4, KAUSAR RAEES3, TAHIR ABBAS2, ASMA YOUNIS1 & KHAWAJA RAEES AHMAD*1

...lt male mice (10 in each dose group) for thyroid and parathyroid histopathology. Tissues were recovered following 48 h of DZ treatment. Micrometric data in terms of follicular size of thyroid, cellular, nuclear sizes of the follicular and chief cells were obtained from the histological sections. Statistical analysis has shown significant (p<0.001) variations in mean follicular size of thyroid indicating dose dependent dep...

SHEIKH AJAZ RASOOL1, MUHAMMAD SALMAN RASOOL2 & MUNAZZA AJAZ3

...ng resulting out of hypo-doses of drug stimulation. Further, the prevalence of Enterobacteriaceae member strains has been witnessed producing Extended Spectrum β-Lactamases (ESBLs) and Carbapenemases. Drug resistance in viral entities has also posed challenge for public health programs. About 20% people die of viral hepatitis in one of Pakistan provinces. A counter malarial acrine drug is being tried against proteinaceous infectious particles (causing man...

ASUMAN ARSLAN DURU1*

...control. These mentioned doses were added to per kg basal diet (166 g crude protein and 2821 kcal ME kg-1). Feed was offered limited (110 g/hen) and water was available ad-libitum. The trial was continued for 8 weeks. At the end of the study, egg yield, egg mass, feed intake and feed conversion ratio of laying hens were not affected by treatments with the addition of GBL (P>0.05). Whereas GBL20 treatment reduced the yolk cholesterol level (P<0.05). GBL10...

Bela Putra1*, Budi Prasetya2

... various gamma radiation doses (0, 5, 10, 15, 20, 25, and 30 Gy). Four replications were done using a randomized block design, with 25 Pennisetum purpureum cv. Mot seeds in each repetition, totalling 700 seeds. The plants were grown in acidic soil with a pH of approximately 4.5–5. After two months of growth, the plants were harvested, and various parameters were analyzed. The results of the research indicated that the application of a 15 Gy dosage signif...

Wasan Ali Hasan1*, Manal Abdulkhaliq Ibrahim2 

...re treated orally with a dose of prednisolone (4.12 mg/kg/d) and subjected to ovalbumin sensitization of the airways; D_group rats received oral famotidine at a dose of 20 mg/kg/d with ovalbumin sensitization of the airways; and E_group rats were given oral prednisolone (4.12 mg/kg) and famotidine (20 mg/kg) with ovalbumin sensitization of the airways. The count of inflammatory cells in the broncho-alveolar lavage fluid was ...

Marwa R. El-Deken1, Raouf E. Rizk1, Mona R. Ahmed1, Fouad A. Tawfeek1, Hossam A. Shahba1, Wesam A. Fares1, Ayman M. Khalifah2*

...d with Glu as additional doses (0.4, 0.6, 0.8 and1%) for Glu2, Glu 3, Glu 4 and Glu 5, respectively. Egg production percentage and egg mass for Glu 3 and Glu 4 groups were significantly improved compared to those for the rest groups. Also, supplementing the diets with all concentrations of Glu acid significantly improved feed conversion ratio besides, eggshell calcium and phosphorus compared to those for control. Moreover, both Glu 3 and Glu 4 groups represent...

Taghreed Jabbar Humadai*, Bushra Ibrahim Al-Kaisei

...animals exposed to toxic dose of tetrodotoxin was characterized by dilation and congestion of portal vein, Focal aggregation of mononuclear cells formation granulomatous like lesion, Various form of nuclear necrosis with number apoptotic hepatocyte, nuclear pyknosis with evidence of councilman body in liver tissue, The Immunohistochemistry study revealed an increase in the scoring of IL1 expression in liver that showed score (3) compared to control group, TNF ...

Waseem Abbas, Imtiaz Ahmed* and Imran Khan 

...ldquo;significantly in a dose-dependent manner with the increasing incorporation of these two herbs” when compared with the CB. When the carbohydrate content of both breads was compared, the functional bread had significantly lower values (p, for all trends < 0.05), respectively, as the ratio of incorporation increased. Total starch (TS) and DS reduced non-significantly at 1 and 2 % and significantly at 3% incorporation as compared with CB. Resistant ...

Safdar Hassan1, Shaukat Ali Bhatti1, Fawwad Ahmad1, Asad Ullah Hyder1, Muhammad Arslan2, Ashar Mehfooz3, Ijaz Saleem3, Muhammad Umar Yaqoob4,5, Mushrraf Nazir1, Muhammad Sharif1* 

...emented with three super doses viz; 25, 50, or 75% of NRC recommended (1994) level and then these diets (Zn-50; Zn-60; Zn-70) contained 50, 60, and 70 mg/kg Zn, respectively. Two hundreds day-old broiler chicks were used for this study. Each diet was fed to a group of 50 broilers (Hubbard, BW 40±3 g, mixed male and female) divided into 5 replicates from day 1 to 35 for their life, raised under the temperature of 34 ± 1.3 °C. Results revealed...

Tianhoun Denté Fidèle1,2*, Meda Nãg-Tiéro Roland2, Zabré Geneviève3, Koama Benjamin2, Kaboré Adama1, Tamboura H. Hamidou1, Bélem Adrien Marie Gaston4 

...ent of the parasite in a dose-dependent manner. The inhibitory concentration 50 (IC50) for egg hatching ranged from 2.189 and 2.994 mg/ml for the hydroacetone and aqueous extracts respectively, and that for larval development was 1.970 for the hydroacetone extract and 2.761 mg/ml for the aqueous extract. The addition of polyvinylpolypyrrolidone (PVPP) to the extracts showed that the tannins present were responsible for the bioactivity observed in both plant ex...
Kalaiselvi Natarajan1, Karal Marx Karuppiah1, Sheena K Baby1, Sakthivel Mohammed2, Shanmugam Seerappalli Aran1 and Suresh Eswaran1*
...ovaprim and ovatide. For dose optimization, the matured brooders were administered with synthetic hormone WOVA -FH at three different doses viz., 0.3, 0.5 and 0.7 and 1.0 ml per kg of body weight at triplicate basis. The highest number of ovulated eggs (3380.5 ±202.75), fertilization rate (90± 0.8) and hatching rate (88±0.88) were observed in the brooders that were induced with 0.5ml per kg of WOVA -FH. ...

Muhammad Adnan1*, Muhammad Nauman Khan2,3, Barkat Ullah2, Faisal Zaman2, Alevcan Kaplan4, Hubert O. Dossou-Yovo5, Sajid Ali Khan Bangash6, Sana Wahab7, Mehreen Ghazal8 and Muhammad Hassan Sarfraz9

...ce before sowing, at the doses of 0 mg/kg (control), 3 mg/kg, 6 mg/kg, 9 mg/kg, 12 mg/kg, 15 mg/kg and 18 mg/kg soil. The different concentrations of Boron (B) were prepared separately by taking a respective amount of boric acid. Pots without supplemented B constituted the control. No additional supplements were applied to the experimental soil. Each pot was irrigated with 100 mL of distilled water with intermittent intervals of 48 hours. All the treatments we...

Shahbaz Hussain1, Asif Ameen2*, Muhammad Ehsan Safdar3, Atif Naeem1, Ahmad Jawad1, Madad Ali1, Muhammad Ather Nadeem3, Ghulam Abbas2, Muhammad Arif2, Muhammad Ahmad Zafar4, Zahid Hassan5

...ides and their effective dose for controlling weeds in DSR fields. A field trial was conducted to appraise the comparative efficacy of three post-emergent herbicides applied at different doses [Clover 20% EC (bispyribac sodium) at 39.54, 59.30, and 79.07 g a.i. ha-1, Pyranex Gold 30% WDG (bispyribac sodium + bensulfuron methyl) at 74.13, 111.20, and 148.26 g a.i. ha-1, and Puma Super 7.5% EW (fenoxaprop-p-ethyl) at 46.33 and...

Hayder S. Rwayyih*, Tahani S.S. Al-Azawi

... (G2) were given an oral dose of alpha lipoic acid (10 mg/kg B.wt). The ovariectomized rabbits in Group Three (G3) were given distilled water. Group four (G4) Ovariectomized rabbits received alpha lipoic acid (10mg/kg B.wt) orally. The results reveal that supplemented groups show a significant decrease in CPK, CRP and troponin serum level. Moreover, there is an increase in heart index (0.45% and 0.41%) as compared with none supplemented intact and ovariectomiz...

Abdelghafour El-Hamzaoui*, Mouloud Lamtai, Laila Ibouzine‑Dine, Sofia Azirar, Mohamed Yassine El-Brouzi, Ayoub Rezqaoui, Aboubaker El-Hessni, Abdelhalem Mesfioui

...ndertaken to examine the dose-dependent impact of GBH exposure over 8-week period on anxiety- and depression-like behaviors in male Wistar rats, administering daily subcutaneous injections of four different doses 25, 50, 75, and 100 mg/kg of GBH while a control group received 0.9% NaCl. Based on behavioral tests (the open field, elevated cross maze, and forced swim), behavioral alterations were detected, specifically anxiety...

Muhammad Ilyas Riaz1, Masood Rabbani1*, Sohail Raza1, Ali Raza Awan2, Aleena Kokab1, and Rida Haroon Durrani1

...I when inoculated at the dose of 108 CFU per mice. In contrast to this, the parent RB51 strain induces splenomegaly and showed higher persistence with significantly higher splenic CFUs in the mice group at 10th and 20th DPI as compared to B. abortus ΔpurD mutant. The histopathological comparison of spleens from both groups also revealed much infiltration of giant macrophages in the B. abortus ΔpurD mice group as compared to the parent RB51 mice gro...
Luis Fernando Díaz-Toral1, Carlos Eddy Alvarado-Zamora1, Ernesto Gonzalo Cañarte-Bermúdez2*, José Bernardo Navarrete-Cedeño2, Gilmar Jesús Cañarte-Cañarte1 and Fernando David Sánchez-Mora1* 
...the appropriate time and dose of application of mepiquat chloride (MC), as a plant growth regulator (PGR), in the Coker cotton commercial variety. This field trial was carried out during February-August 2020 in La Teodomira experimental farm of the National Institute of Agricultural Research (INIAP, Lodana, Manabí, Ecuador), with three periods of application and four doses of growth regulator in addition to control (w...

Faisal Ali1, Abdul Aziz Khakwani1, Iqtidar Hussain1, Ghazanfar Ullah1, Atiq Ahmad Ali Zai2, Moneeza Abass3, Zuhair Hasnain4* and Sara Zafar5*

... of different fertilizer doses on the yield, biomass and the response of different cultivars of sweet sorghum, during the Kharif season (2015–16). The study was carried out using a split-plot layout and a randomized complete block design (RCBD). The cultivars of sweet sorghum were chosen for the main plots, while fertilizer doses were distributed in the sub-plots. Fourteen parameters were monitored throughout the study...

Saira Jabeen1, Muhammad Avais1*, Jawaria Ali Khan1, Kamran Ashraf2, Aftab Ahmad Anjum3

...of vaccine, with booster doses at 15-day intervals following the priming. Serum samples were collected biweekly over a 60-day period, and the antibody titers were measured using IHA test. Geometric mean titers (GMT) were computed and subsequently analyzed statistically. The results indicated that the E. coli (aggR) isolate exhibited immunogenicity in rabbits, with the antigen concentration of 10^10 cells/mL yielding highest antibody titers. Vaccines demonstrat...
Danish Riaz1,2, Syed Makhdoom Hussain2*, Majid Hussain3, Muhammad Zubair-ul-Hassan Arsalan4 and Eman Naeem2
...porating probiotics at a dose of 2.5 g/kg resulted in the best growth performance, highest nutritional digestibility, and best hematological indicators in the fingerlings. Finally, the optimal dosage of probiotics for supplementation was shown to be 2.5 g/kg.

...

Moazama Batool1*, Syeda Ansa Fatima1, Saima Naz2*, Qurat Ul Ain1, Sheeza Bano1, Ghulam Abbas3 and Ahmad Manan Mustafa Chatha4

...ublethal (1/3rd of LC50) doses of bifenthrin i.e., 2.16 µg/L for 30 days. Behavioral parameters of C. idella were observed at acute as well as sub-lethal concentrations. It was observed that behavioral parameters of C. idella such as opercular movement, somersaulting activity, convulsions rate, air gulfing was significantly (p<0.05) increased by increasing the bifenthrin concentration. Fin movements and swimming rate was also increased with increase i...
Shahid Iqbal Khattak1, Mohammad Safdar Baloch*1, Khalid Naveed2, Muhammad Amjad
Nadim1, Asghar Ali Khan1 and Kaleem Ullah3
...n. Potassium
doses viz. 0, 12, 18, 24, 30 and 60 kg ha-1 were applied in foliar form at tillering, booting
and heading stages of wheat. The course of study revealed that foliar application of K2O in
booting stage produced maximum leaf area index (LAI), leaf area duration (LAD), crop
growth rate (CGR), net photosynthesis rate (NPR) and grain yield, while its application at
heading stage produced maximu...

Arshad Javaid1* and Iqra Haider Khan

...ing. All the
doses of soil amendment significantly suppressed root length by 21–48% over control. A
1.2% soil amendment significantly reduced biomass of parthenium seedlings by 23%. This
study concludes that leaf and stem extracts of parthenium possess potent herbicidal
potential for control of parthenium.
...

Salman Ali1*, Muhammad Arif1, Mehran Ali1, Muhammad Afzaal2, Gohar Saeed32, Muhammad Bilal4, Fazal Munsif1 and Sajjad Zaheer1

... practice. Usage of high doses of herbicides for killing weeds has created several ecological and environmental problems which cannot be overlooked. Therefore, other weed control practices and techniques should be adopted to minimize weed-crop competition and increase the growth and productivity of crop, instead of chemicals. An experiment was established at Agronomy Research Farm, the University of Agriculture Peshawar to evaluate the effects of biochar and o...

Shabnam Javed1 and Amna Shoaib2

.../div>
viability in dose dependent manner. Preliminary results suggest the promising anticancer
potential of n-hexane and ethyl acetate S. tomentosa against lung A-549, hepatocellular
HepG2and urinary bladder EI-138 cell lines. Further studies are required to know the
mechanism(s) involved in the cell death.
...

Afrah Adil Hassan1*, Hawraa F. H. Alowaid1, Majdy Faisal Majeed2 

...ours after the last oral dose administration upon completion of the 30-day trial. The liver was promptly removed for an assessment of the changes in malondialdehyde (MDA), glutathione (GSH), and myeloperoxidase activity (MOP). Proinflammatory cytokines (TNF-α and IL-1β) were measured in the plasma samples, and an evaluation of the liver histological profile was conducted on liver samples. The results indicated that lead toxicity significantly (p≤...

Mushtaq A.Alabodi1*, Imad Majeed Almeeni2 

...as a single subcutaneous dose to suppress or delay the estrus cycle in queens. Ten domesticated non-pregnant cats of known origin aged between 1-3 years were used. The cats were divided randomly into two groups. The first group (G1, n=5) was left without treatment and served as control group, and the second group (G2, n=5) was administered 18 mg melatonin implants as a single-dose subcutaneously. Before starting treatment at...

Liyun Chang1*, Yumei Cai1, Chenghui Li1 and Jianhua Qin2*

...ns were immunized with a dose of 50μg/chicken, respectively, and strengthened immunity one week later. At 7th, 14th, 21st, 28th, 35th day post-injection, respectively, after extracting the total DNA from fresh tissues of immunized chickens, the 3-1E gene was amplified by PCR, the serum IgG antibody was detected by routine ELISA, peripheral blood lymphocyte proliferation response was evaluated by cell proliferation assay. The results showed that a target ban...

Eman Ali Hussein1*, Majdy Faisal Majeed2

...r injection of (SZ) at a dose of 50 mg/kg body weight, In contrast, rats in groups 3 and 4 were given oral gavages of TFG herbal extracts (0.15 g/kg BW) in addition to being kept on an identical experimental protocol to that of the rats in groups 1 and 2, respectively. While group 5’s diabetic rats that received orally gavages 3.5 mg/kg of glucophage XR treatment served as positive controls. Treatment with TFG of groups 3 and 4 recorded significantly (p&...

Aya A. Saber1, Mohamed Fawzy2*, MokhtarM. EL-Tarabili2, Eman K. El Sayed2

...he 6th month post-second dose/vaccination. Following up, the RVF-SNT antibody titers in the 1st-week post first vaccination showed that it was 3.2 in a group 2 and 4.4 in a group 3. Both groups showed RVF-SNT titers’ peak by the 3rd-week post-vaccination by a mean titer of 70.4 in a group 2 and 102.4 in a group 3, then it declined to 3.6 in both groups at the 6th-month post-second dose. Indirect ELISA test results vali...
Muhammad Shakil Ahmad1, Muhammad Afzal1, Liu Yu Feng2
Muhammad Zeeshan Majeed1*, Hina Safdar3, Arif Mehmood1, Shahid Iqbal4 and Muhammad Adnan1
...both half and one-fourth doses of flubendiamide and chlorantraniliprole (19.51 and 19.63 days and 17.77 and 17.20 days, respectively), while pupal duration prolonged for spinetoram and lufenuron. Similarly, significant suppression of adult lifespan was exhibited by flubendiamide (11.83 and 11.85 days) and chlorfenapyr (12.28 and 12.06 days). Overall study results advocate further consideration of these aforesaid biorational insecticides against S. litura infes...
Inayat Ullah Awan, Mohammad Azam Khan, Muhammad Zareef , Ejaz Ahmad Khan
M. Farooq,G. Haider,K. Jabran,A. Khaliq,S.M.A. Basra,A. Razzaq, Z.A. Cheema

Manar Neamah Al-Shreefy*, Suhaib A.H. Al-Taai 

... euthanized using an overdose of ketamine HCl (85-95 mg/kg BW). The topographic position of organs was observed in situ, and samples were collected in 10% neutral buffered formalin for routine histological procedures. The results showed that in neonate guinea pigs, the esophagus was a narrow muscular tube approximately 1.47±0.02 cm in length and 0.044±0.02 gm in weight, divided according to its position into three portions. The stomach was a tran...

Habib Asshidiq Syah1, Aulia Puspita Anugra Yekti1, I Putu Arya Girinata1, Ahmad Fahrudin Husen1, Rizki Prafitri1, Nurul Isnaini1, Nanang Febrianto1, Putri Utami1, Muhaimin Rifa’i2, Trinil Susilawati1*

... acceptors with a single dose of unsexed semen of 100 before being exposed to FMD (T1) and 115 cows affected by FMD (T2) in Pujon subdistrict, Malang Regency, with a Body Condition Score 2.5-3.5 and aged 1.5-8 years and showing signs of estrus. Using the method of descriptive statistics. The percentage of AI success of T1 and T2 based on NRR-1 values showed no significant difference (P>0.05) 77.00% vs 86.96%, NRR-2 values showed no significant difference (P...

Marah Salim Hameed1, Raad Mahmood Hussein Al Zubaidi2, Ali Ibrahim Ali Al-Ezzy3*

...ia azedarach at 28mg/day dose has significant effects on serum cholesterol level and total serum albumin. Aqueous extract of Melia azedarach at 28mg/day dose has significant effects on total serum bilirubin. Ethanolic and aqueous extracts of Melia azedarach have equal effects on ALT, AST, ALP enzymes and innate inflammatory indices for white New Zealand rabbits.
 
Keywords | Inflammatory indices,...

Chun Shi*, Ziyu Cao, Mingyuan Yang and Meijing Zhai

...terility agent) and high dose (20 mg/kg of plant complex sterility agent) groups. Hematoxylin and eosin staining is used to observe the pathological changes of testis tissue. The testis organ index, male seminal vesicle, and sperm were also detected. The expression of FAM209, and PICK1protein in testis tissue are detected by Western blotting. Compared with the control group, the cell structure in the testis tissue of the model group is damaged, and testis orga...

Sara Brikat1*, Imane Kherrab1*, Yassine Taaifi2*, Sara Haida3, Laila Ibouzine-Dine1, Oumaima Abouyala1, Ilhame Fitah1, Abdelhalim Mesfioui1, Aboubaker Elhessni1 

...s treated with different doses of MECL (2000, 3000, and 4000 mg/kg) for 14 days. For the evaluation of antidepressant, antioxidant activities and memory performance, rats were randomly distributed into six groups included Control, Group (2) provided with a 23% fructose solution for one month; Group (3), administered 0.1 g/kg/d of MECL for 10 days, followed by fructose solution; Group (4) treated with 30 mg/kg/d of losartan for one month alongside a fructose so...

Roshan Ara1, Muhammad Ali Khanzada1, Amir Khan Korai1*, Abdul Mubeen Lodhi, Anam Mehwish Khanzada1, Khalid Hussain Qureshi1, Shakal Khan Korai2*

...lli plant growth. Higher doses of nematicides were more effecctive, with some treatments completely removing nematode presence in roots and soil. Actara (500 ppm, 1000 ppm, and 2000 ppm), Furadan (50 ppm to 2000 ppm), Ulala (1000 ppm and 2000 ppm), and Rugby (250 ppm to 2000 ppm) treatments completely inhibited root knot formation. Furadan at 2000 ppm produced the longest roots, whereas Actara at 2000 ppm produced the most shoot length and weight. In conclusio...
Naveed Ahmed
...ximum protection at 2.0% dose in both methods of application and in both localities....
Shakeel Haider Zaidi, Ch. Muhammad Muslim, Muhammad Shabbir Mughal and Imtiaz Hussain
...the application of split doses of 200 kg nitrophos/ha....
Mirza Hakim Khan
...ntrol applying different doses of 2-4-D Sodium, Amine and Ester are suggested in this article....
Hanif Gul, G. A. Bajwa and G. N. Panhwar
...aulownia spp. At the dose rate of 0.2% of given formulations. All the test insecticides reduced the pest population significantly over control with Mepra 50 EC most effective affording 2.4, 108 and 0.97 individuals of D. stebbingi per 225 cm2 bark area after 24, 48 and 72 hours of treatment, respectively. In the second experiment same five insecticides were sprayed on stems of Jacranda mymosipholia at the
Hanif Gul and Abida Hamid
...ana was tried in the doses of 0.4 x 104 spores / ml 0.6 x 104 spores/ml and 0.8 x 104 spores / ml against all stages of Hadde beetles. The fungus B. bassiana proved to be effective against all the stages except eggs. For grubs among the three doses 60% mortality occurred after 120 hours in the dose of 0.8 x 104 spores / ml while 53% and 33% mortality was recorded by other two
G. A. Bajwa and G. Zimmermann
... 21 days. In the highest dose (8%) maximum mortality was recorded after 72 hours which may be due to contact action of neem oil formulation. On the other hand, the lower doses caused slow mortality in the beginning and progressed steadily, owing to growth regulating behavior of neem. The neem formulation at 6.4% and 8% were phototoxic to Prunus domestica....
Muhammad Shabir Mughal and Shams-u-din Jalbani
... to be tested were three doses of well rottened leaf mould manure of Paulownia spp. (Control no manure and treatments 75, 150 and 225 gm/ treatment) applied to soil in earthen pots (380 cm2) supplemented with 10 gm Urea fertilizer/pot as basal dose in all treatments and control. Results indicated that seed germination was insignificant affected and better plant growth and height was observed in all t...
Sardar Muhammad Rafique
...nt at the uniform single dose of NPK (1:2:2) at the rate of 100 Kg N, 200 Kg P and 200 Kg K. The experiment was twice replicated. The study has revealed that floristic composition of grass and forbs species had improved manifolds. The vegetation cover percentage, herbage production, species composition, species distribution and number of species had increased under combined effects of protection and fertilizer application. The Poa alpine - Potentilla fraga...
S. M. Rafique
...st 3 years with uniform dose of NPK (1:2:2) at the rate of 100 kg N, 200 kg P and 200 kg K per ha/year. The results indicated manifold increase in protective and vegetation cover and forage production under combined effect of fertilizer application, protection and over sowing compared to conventional grazing. Forage production was 5 times higher under fertilizer application. The study has demonstrated that range improvement activities will not only en...
Hanif Gul, Nighat Mansoor Chaughtai and Rukhsana Kausar
...s was tested in the doses of 0.8 x 104 spores/ml, 0.6 x 104 spores/ml in the study. The data showed that B. bassiana has given a non- significant result against the pests even after 72 hours but results were significant after 96 hours upto 168 hours of treatment. The study showed that after treatment the fungus first established and then caused the mortality of Poecilocerus pictus within 2-3 days while in case of Brachutypes porten...
Ghulam Ali Bajwa and Hanif Gul
...icarb) was used in five doses of 0.0 (control), 0.4, 0.8, 1.6 and 3.2 g/plot (1.33 sq. ft) to evaluate any phytotoxic or phytotonic impact on Paulownia tomentosa PFI No. 19, at nursery stage. Measurements of parameters recorded one month and twenty days after treatment were plant height, number of leaves per plant, fresh weight of leaves, fresh weight of stem, dry weight of leaves, dry weight of stem and percent dry matter. Five plants per trea...
Sardar Mohammad Rafique
...e fertilized with single dose of NPK (1:2:2) at the rate of 100 kg N + 200 Kg P + 200 Kg K per ha in split plot design. Ten permanent sample plots of 1 x 1 meter size (Braun - Blanquet's method) in each sub plot were established for estimation of forage production by clipping method, cover percentage and percentage soil protective cover. The study revealed 2.3 times improvement in forage production at present production level through protection (zero grazing)...
Wali-ur-Rehman
... each in 0.05 and 0.03% doses and 83% larvae in 0.01% dose while Laser 25% EC gave 80, 43 and 33% kill of larvae, respectively in 0.05, 0.03 and 0.01% doses. Malathion showed poor results with 36.6 and 26.6% mortality of larvae in 0.05 and 0.03% doses, respectively. In another trial (a fumigant caused 100% mortality of adultas of stored seed pests...
Shakeel Haider Zaidi, Anwar Ahmad Khan and Muhammad Muslim
...planting and appropriate doses of NPK fertilizer required for better growth and yield was determined. The plant is perennial at higher hills and good yield of leaves was recorded during second and third year's growth of the plant. Roots of A. acuminata attained exploitable size after three years growth....
Hanif Gul and M. Ismail Chaudhry
..., cypermethrin 10 EC in doses of 0.01, 0.02, 0.04 and cislin (deltamethrin) 2.5% in doses of 0.01, 0.02 and 0.04% Dieldrin 20% EC in 0.5% dose was used as standard for comparison along with check (no treatment). Half of the stacks were sprayed for the second time, three months after first spray with the same insecticides in same doses. Observation...
Anwar Ahmad Khan and Shakeel Haider Zaidi
...um.Application of split doses of NPK at the rate of 150:30:30 kg/ha significantly increased the yield of green herb as compared to other doses.The mint oil content are comparable with the main producing countries like Japan, India and China. Pilot-scale cultivation of Japanese mint in the irrigated areas is recommended to the farmers for growing as specialized crop....
Wali-ur-Rahman and M. I. Chaudhry
...e 80% larvae in the same dose within 24 hours. In lower doses of 0.01 and 0.02% antimoultants caused 60 to 75% and insecticides 70 to 80% larval mortality in the same periods. The pest was controlled by spraying Malathion 57% E.C. in 0.17% concentration on the resting caterpillars at the natural enemies of the pest....
Anwar Ahmad Khan and Shakeel Haider Zaidi
...g N and 65kg P/ha basal dose gave higher yield as compared to control. ...
Ghulam Sarwar Khan
...font>s of 7to 15 KR doses showed significant increase in tillering, plant height, fresh and dry matter yield. Flowering was earlier in 5 to 15 KR and delayed for other doses. Germination was not much affected. Pollen fertility gradually decreased with the increase in radiation dosage....
M.Ismail Chaudhry and Ashiq Ahmad
...lux gave 92%kill in 0.05%dose and 100% kill in 0.1%dose....
M. Ismail Chaudhry and Hanif Gul
...ell as field trials, in doses of o.02 and 0.04% concentrations gave cent percent mortality of the larvae. The residual effect of the insecticides continued up to about one month and provided cover for two successive and overlapping generations the non-target insects, which do not feed in foliage were absolutely safe from the adverse effect of the chemicals....
Mohammad Iqbal Sheikh
...has been found that the dose of water was insignificant. However, clones between themselves showed different rates of growth; significant at 1%level for dia and height and at 5%for volume; 1-69/55 showing the overall best performance followed by 1-4/64, 1-90/60 showed the poorest growth....
Pervez Khawaja, I. A. Hafiz and M. I. Chaudhry
... of the test larvae with dose of 0.8 x 105, 1.6 x105, and 3.2x105 spores per ml against a natural mortality of 34.4% larvae in the check. The efficacy of the product has been proved against this insect hence it can be used on field scale to control the peat. ...
M.I. Sheikh and S. H. Bangash
...the older plants. Higher dose of the fertilizers is recommended for future trials. ...
Hanif Gul and M. Ismail Chaudhry
....05%, 0.01%,0.2%, and 0% doses in field trial against land snail, Helix asperasa attacking nursery plants. Baylucid gave 75% and 100% mortality in 0.05% and 0.1% concentration respectively, 72 hours after treatments while Barestan gave 70% and 80% mortality in 0.1% and concentrations as against a natural mortality of 23% to 33%. Nogas and Sodium Chloride were less effective....
Wali-ur-Rehman and M. Ismail Chaudhry
...f nymphs only in highest dose and smaller plants. Disyston other insecticides other insecticides showed no effect against the pest. In check all nymphs survived but 1-6%adults were found dead after a month. ...
Bashir Hussain Shah, Hanif Gul and M. Ismail Chaudhry
...ality of larvae in 0.01% dose. Sumithion in 0.025% and Lorsban in 0.05% concentration also gave 100% mortality of larvae within 3 days of treatment. ...

Sundus Oun Ali Al-Zaini1, Mohanad A. Al-Bayati3*, Khazaal Abbas Khazaal2, Salma Talib Salih1

...or fish along five days, dosed: 0.63g/fish/day and 1×109cfu/fish/day, respectively. The first two groups of fish were challenged by mingling them with KHV-infected fish at a ratio of two infected fish to ten vaccinated fish under simulated acclemtized normal condition. In contrast, fish from the second group were challenged with live Aeromonas hydrophila at a dose of (3×108cfu/fish and 3×107cfu/fish) for 22...

Sura Ayed Radam*, Inam Badr Falih

...eund’s adjuvant, 2 doses, 14 days intervals, 2nd group was immunized s/c with Concanavalin-A Con-A (1.5 mg/ml), 3rd group was immunized with mixed S. pyogenes Ag. and Con-A, 2 doses, 14 days intervals, and 4th group was given Phosphate buffer saline (PBS) as negative control group. Results Analysis of cellular and humeral immunity recorded higher concentration of Immunoglobulin G IgG, Tumer Necrosis Factor alpha TNF-a ...

Sony Eka Nugraha1*, Marianne Marianne2, Rony Abdi Syahputra2, Aji Najihudin3, Nikmatul Ikhrom Eka Jayani4, Shaum Shiyan5, Nabila Nabila6,7

...hrombocytopenic effects; doses of 100 and 200 mg/kg BW showed significant improvement in the hematology profile from that of the heparin control (p < 0.05). In particular, doses of 200 mg/kg BW have the best potential for the development of anti-thrombocytopenic agents. Furthermore, an in silico study found that the main compound of C. papaya interacts with multiple amino acid residues, indicating stable binding affinity....

Fatima Aziz Mahdi Al-Badry

...nths), respectively. The dose of Puma was given for rats by gavage. At the end of experiment period for each group, blood was collected and serum obtained in purpose of chemical examinations were included functions of kidney as (urea and creatinine) and liver enzymes (ALT, AST and ALP). After that, all rats were dissected then kidney and liver were eradicated for histopathological examinations. The results indicated to puma administration led to significant in...

Amal Mohammed Ali Alah Al-Marmadhi*, Saadeya Ali lefelef Al-Gnami

...allicin nanoparticles at dose 50 mg/kg of B.W appears to enhance its bioavailability and effectiveness combating oxidative stress associated with hyperthyroidism.
 
Keywords | Allicin nanoparticles, Methimazole, Hyperthyroidism, T3, T4 and TSH, Iodine levels, Thyroid gland, Female rats, Herbal medicine, Garlic and biochemical
...
Muhammad Naeem Korejo1*, Muhammad Nawaz Kandhro1, Aijaz Ahmed Soomro1 and Niaz
Ahmed Wahocho2
...nd herbicides at reduced doses controlled weeds efficiently and optimum
enhancement in seed yield of mungbean was noticed at three irrigations.
...
Mamoona Arooj1, Bilal Ahmad Khan*1, Muhammad Ather Nadeem1, Muhammad Mansoor
Javaid1, Erum Rashid2, Muhammad Saleem Jilani3, Jamshahid Qamar1, Faryal Ali4, Sadaf
Javeria5, Muhammad Faisal4
...ulation due to ultra-low doses of different herbicides in several crop
species has been observed both in controlled as well as in the field conditions; however
available data of hermetic effects on weeds growth is very limited. This study investigates
the promotive effect of low doses of atrazine on growth of Tribulus terrestris. Pot
experiments were conducted at Agronomic Rese...

Tariq Ahmed Keerio1*, Muhammad Nawaz Kandhro1, Ahmed Naqi Shah1, Muhammad Ibrahim Keerio2, Ghulam Murtaza Jamro3

...e
at reduced doses controlled weeds efficiently and optimum enhancement in kernel yield
of m aize at a seed rate 30 kg per ha
...

Lin Li1*, Lu Lu2, Gang An2 and Xiaoguang Zhang3

...PE cells and the optimal dose of TF-TP were detected by CCK-8 method. The morphology in the cells were observed under the inverted microscope electron microscope. The apoptosis of the cells was assayed by Hoecht staining. The expressions of TF, Bax and Bcl-2 in the cells were determined by Western blot. After treatment with TF-TP 150 μmol/L, the cell monolayer adhered to the wall, which was fusiform or polygonal. The suspended cells and cell debris were sig...

Hala Harifi*, Mouloud Lamtai*, Siham Ait Salhi, Fatima-Zahra Azzaoui, Omar Akhouayri, Abdelhalem Mesfioui, Leila Bikjdaouene

... intoxication. Different doses ranging from the lowest to the highest (6 mg/kg, 25 mg/kg, 30 mg/kg, and 40 mg/kg i.p.) were administered intraperitoneally over a period of 12 weeks. The objective of the study was to identify the lethal dose and the tolerated toxic dose in order to establish a toxicity model. Weight gain was monitored weekly, and, at the end of the exposure period, the rats...

Hind A.Norii1, Adel M.Hassen ALZobidy2* 

... was clearly observed at doses of 150 and 250 mg/kg bw on the release of estrogen and progesterone. Taken together, our findings illustrate that Vitex agnus-castus alcoholic extract impact the physiological parameters of female rats.

...

Tamara Natik Dawood* 

...ncreased with increasing dose (P <0.05). On the contrary, the value of feed conversion efficiency, triglycerides and cholesterol were decreased in G1 and G2 compared to G3 (P <0.05). Furthermore, feed conversion efficiency, triglyceride, and cholesterol decreased with increased dose used (P <0.05). Ultimately, we can conclude that Silymarin can improve hematological and biochemical parameters and decrease feed conve...

Hafizuddin1, Sri Wahyuni2, Tongku Nizwan Siregar1*, Amalia Sutriana3, Ririn Triyuliani4, Siti Hanyyah Herviani4, Muhammad Farhan Syuhada4, Nur Salimah4, Muharni Mardiah Eriswandi4, Ratu Permata Ayu4, Putroe Hayatun Nufus4

... ml each while the total dose in R3 was 28 mg. Intramuscularly injections in both groups were performed 5 times with a 12-hour interval. The administration of NaCl in R1 and BPE in R3 was 1; 0.5+0.5; 0.3+0.3 mL, respectively while the injection of FSH in R2 was 4; 4+4; 8+8 mg. Subsequently, rabbits in R2 and R3 were injected with 100 IU hCG and mated with males, while those in R1 were mated without hCG administration 24 hours after the last FSH and BPE treatme...

Hawraa F.H. Alowaid1*, Afrah Adil Hassan1, Majdy Faisal Majeed2

...lity and low price. High doses or prolonged administration of TML are linked to hepatic and renal damage. There is currently no known precise mechanism for how TML damages the liver and kidneys. The goal of the current investigation was to assess the potential contribution of oxidative stress dysfunction to the etiology of renal and hepatic injury brought on by TML. For this purpose, male adult rats were treated with TML (15 and 30 mg/kg/day oral administratio...
Marchel Putra Garfansa1, Roy Hendroko Setyobudi2, Iswahyudi Iswahyudi1, Shazma Anwar3
Damat Damat2,Tony Liwang4, Mardiana Sri Susanti5, Diah Hermayanti2*, Meddy Setiawan2
Thontowi Djauhari Nur Subchi2, Dewi Mariyam6, Yolla Muvika Ananda2, Satriyo Krido Wahono7
Adil Basir8, Musrif Musrif9 and Anwar Saeed Khan10
...s research. PET MPs at a dose of 600 µg had the worst impact on mice compared to the others. There were changes in eating performance, body weight, and mice feces in treatment P1 due to the MPs contained in them. Another consequence is anticipated: A reduction in microbial diversity in the intestines of mice, resulting in a fall in both feces and body weight of the mice. 
...

Muhammad Salman1, Rao Zahid Abbas1*, Muhammad Kasib Khan1 and Muhammad Shahid Mahmood2

... The results indicated a dose-dependent effect of C. verum essential oil showing 20% concentration to be the most effective in view of the acaricidal and the repellent activities. Hence, this essential oil can be considered as a potential candidate for the effective control of cattle tick (R. microplus).

...

Endy Triyannanto1, Danung Nur Adli2, Diah Pratiwi3, Lukman Hakim3, Selma Noor Permadi3, Taufik Kurniawan3, Angga Maulana Firmansyah3, Lina Ivanti3, Dinar Suksmayu Saputri3, Mohammad Miftakhus Sholikin4, Hari Hariadi5, Tri Ujilestari3, Teguh Wahyono3* 

...atabase. The irradiation dose varied between 0 and 50 kGy during the meta-analysis. A mixed-model technique was applied to perform the meta-data analysis, with the gamma irradiation dose considered as fixed effects and the different research (articles) as random effects. Gamma irradiation reduced hardness, gumminess, and chewiness of pork (p < 0.01). Meanwhile, gamma irradiation increases pH values at 0 and 7 d after stor...

Junaid Khan* and Muhammad Sajid

...lsquo;effect of nitrogen doses (0, 75, 150 and 225 kg ha-1) and timing (September, October and November) on fruit quality of guava in winter’ was conducted at farmer field of village, Gher Khan, District, Haripur during 2017-2018 with the objectives to optimize the appropriate dose of nitrogen and timing of application for growth and fruit quality of guava crop in winter. The experiment was laid out in RCBD with split ...

Waqas Ahmad Shams1*, Gauhar Rehman2, Muhammad Ismail3, Rahmul Kabir4 and Abdul Qahar1

...ract showing significant dose-dependent activity. Overall, our findings suggest that both aqueous and ethanolic extracts possess substantial antioxidant potential, warranting further validation through in vivo experiments and clinical trials. This study underscores the promising therapeutic applications of Crab Himalayapotamon emphysetum extracts as natural antioxidants in combating oxidative stress-related diseases. 
 
Saadeya Ali Lefelef Al-Gnami1, Fatima Ibrahim Mohammad2, Huda Jassim Mohammed Al-Helali3
...the T4 group at the same dose. The T5 group received a single oral dosage of vitamin C and dexamethasone. After the end of experiment the animals were dissected and blood samples were collected for measuring Hb levels, PCV, mean cell volumes, MCHC, and RBCs, and the livers samples were removed from all animals and reserved them in formalin 10% for histological examination. The results of the present study exhibited a notable rise (p<0.05) in RBC count, Hb, ...

Fasih Ullah Haider1,2, Sardar Alam Cheema1and Muhammad Farooq1,3

... options that reduce the dose of herbicides and these are harmonious with the objectives of conservation agriculture. Regardless of much importance of cover crops and their worth in agricultural systems, cover crops have certain negative aspects as well. They compete with cash crops for moisture, solar radiation and nutrients which ultimately decrease the return of cash crops. Farmers are still hesitating to grow cover crops in their farming systems due to lac...

Gul Hassan, Anees Amin, Haroon ur Rashid, Naqib Ullah Khan and Hussain Ali1

...luded NPK at recommended dose alone and NPK + 1, 2, 3 and 4% dried parthenium (w/w of soil). For comparison, treatments like dried berseem 2% (w/w) and untreated (0 NPK and 0 Parthenium or berseem); were also employed. The experiments were replicated four times as factorial in completely randomized design (CRD). Eight seeds each of sorghum and maize were separately seeded in each pot ultimately thinned to 5 plants per pot. Since the statistical differences bet...

Essa D Alhtheal1*, Sufian S Salman2, Salah M AL-Kubaisi3

...nanoparticles with their doses alone was compared. The investigation of possible side effects of treatment regimens used. This study aimed to prepare chitosan nanoparticle and cyclosporine loaded on nanochitosan and pure chitosan. Pure chitosan was prepared using the gelation method. The appropriate cross-linking ratio and cross-linking times of 2% (w/v) chitosan CNPS/cyclosporine nanofibers and solution were prepared. It was dissolved in deionized water at a ...

Ibrahim Ali1,2, Hanan Mohamed Fathy Abdien1*, Wael Kamel Elfeil1, Mohsen Mohamed Zaky ElDemerdash1, Mohamed Ali Zain El-Abideen2,3, Walid Hamdy Kilany2,3

... the primary vaccination dose intramuscularly only on day 7 of age. Group G6 served as a positive control (untreated and challenged), and G7 served as a negative control (untreated and unchallenged). Chickens were challenged at day 35 of age with 106 EID50 of widely circulating H5N8 strain in Egypt to evaluate vaccine potency, efficacy, and safety. Results indicated that polymer GEL01/IM G2 and ISA70/IM G5 successfully conferred a high humoral immune response,...

Roy Sukbir Singh1, Jekson Martiar Siahaan2,3*, Endy Juli Anto4, Syafruddin Ilyas5, Putri Eyanoer6, Hendrika Andriani7,8

...s receiving Aloe vera at doses of 200, 300, and 400 mg/kgBW/day. At the end of the study, lipid profiles, MDA (malondialdehyde), and Hs-CRP (high-sensitivity C-reactive protein) levels were assessed. The in silico results indicated strong binding affinities for aloin in TNF-α, and Aloinoside in COX-2, this suggesting its potential inhibition of these targets. Moreover, at doses of 400 mg/KgBW Aloe vera extract had a si...

Wazir Ahmed1*, Muhammad Naeem Akhtar2, Muhammad Waseem Akhtar3, Muhammad Nauman Hanif1, Aiman Salah ud Din4 and Ahmad Mahmood1

...s found to be an optimum dose for regulating seed dormancy and post-germination growth positively. However, CaC2 >16 mg petri-plate-1 proved lethal and suppressed the germination or growth of the seedlings. Compared to control treatment, improvements in seed sermination and growth variables, i.e., 8 to 37% in seed germination, 5 to 22% in seedling biomass, 5 to 46% in shoot length, and 3 to 37% in root length, suggest that calcium carbide, easily available ...

Bilal Ahmed1, Faheem Ahmed Khan2, Nuruliarizki Shinta Pandupuspitasari1*, Muhammad Rizwan Yousaf1 and Asep Setiaji1 

...ble insights into future dose-dependent studies to address the methanogenic potential of yeast-based products recognizing the urgency of identifying effective mitigation strategies while maintaining productivity. As the cattle industry seeks sustainable solutions, further research should explore alternative strategies and optimize interventions for both productivity and environmental sustainability.

...
Mohammad Moneruzzaman Khandaker1*,Nuratiqah Emran1, Nurul Elyni Mat Shaari1, Arba Aleem2, Zanariah Mohd Nor1 and Ali Majrashi3
...ub> was lower than lower doses of Cd. Chlorosis symptoms in the leaf were visible in hydroponic Pak Choi containing Cd. The growth of Cd-treated hydroponic Pak Choi was adversely affected by Cd treatment. The Cd treatment also reduced SPAD, biomass content (fresh and dry), and length of root and leaves number significantly. It can be concluded that exogenous Cd inhibits the Pak Choi germination and growth under hydroponic conditions. 
...

Rawya Sh. Mohammed*, Baraa N. Al-Okaily 

...and CurSeNPs at the same doses. Blood samples were collected from anesthetized rats; serum was analyzed to assess levels of FSH, estrogen, TGF-β, and NF-κB. Additionally, ovarian tissue was extracted to measure levels of malondialdehyde (MDA) and superoxide dismutase (SOD) concentrations, and to estimate ovarian gene expression of PTEN. The findings indicated a notable decrease in tissue SOD, serum FSH, and estrogen levels, along with an elevation i...

Elham M. Hosny1*, Saad Mahmoud Saad1, Marionette Zaghloul Nassif2, Amani Mohamed Salem1

...cans into at an infected dose of 105 cfu/g. The initial group (control 1) did not get any inoculation or treatment. The second group (control 2) received an inoculation without treatment. The third and fourth groups were thoroughly mixed with 0.5 mg/ml of SPP and 6 mg/ml of PEE, respectively. All samples were refrigerated at 4°C for duration of 12 days (n = 4 for each group at each examination day). The obtained results confirmed that the tested concentrat...

Nasr Tarq Mohammed 

...strates the significant, dose-dependent anticancer effects of aqueous garlic extract on breast cancer cell lines, highlighting its potential as a promising and accessible therapeutic agent in cancer treatment strategies. 

...

Hina Yasin1,2*, Shaukat Mahmud2, Hina Abrar1, Kaneez Fatima3, Rabia Bushra1 and Saima Zahid2

...extracts in differential dose pattern (81, 54 and 27 mg/kg). Cytotoxic activity was assessed by the Brine shrimp bioassay method. Results showed that extracts significantly responded as analgesic drug comparable to standard drug using different methods of evaluation for analgesic activity. Brine shrimp bioassay in different leaves extracts also showed similar effects likewise to the standard drug vincristine sulphate. All extracts exhibited marked cytotoxic ac...

Emad M. Gad1, Haidy G. Abdel-Rahman2, Mohy Eldin Abd-El-Fattah1, Merna M. Kamal1, Ahmed Shaker Eltahan3, Amina A. Dessouki3*

...njection of a low single dose of STZ (40 mg/kg) after being fasted for the whole night. Sixty albino rats were separated into six equivalent groups. Group I control rats administrated 0.5ml distilled water by gavage for six weeks, group II untreated diabetic rats, group III–VI are diabetic groups; received dapagliflozin (1 mg/Kg daily) by gavage for 6 weeks, mulberry fruit extract (300mg/kg b.wt) by gavage, mulberry leaves extract (250 mg/kg b.wt) by gav...

Abdulla A. Albishtue1,3, Nurhusien Yimer1,5*, Md Zuki A. Zakaria2, Abd Wahid Haron1, Abdul Salam Babji4

...d lead acetate (LA) at a dose of 10 mg/kg BW along with increasing doses of EBN at 0, 30, 60, and 120 mg/kg BW each day, respectively, for five weeks. Behavioural changes were monitored in the various groups. Blood sample for measurement of redox status markers (thiobarbituric acid reactive substances (TBARS) and total antioxidant capacity (TAC)) and brain tissue samples for histopathology, were collected after euthanization...

Zhongjiang Niu1, Periyannan Velu2, Annamalai Vijayalakshmi2*

... reversed with NF45 in a dose dependent manner. P2y agonist, methylene - ATP, significantly reduced the positive effect of NF45.P2y3 receptors had a significant role in epilepsy kindling. This mechanism has potential in epilepsy therapy and future research.

...

Rawya Shakir Mohammed*, Baraa Najim Al-Okaily

...d to Group 3 at the same doses. Ovarian tissue specimens have been taken to determine the level of ovarian VEGF mRNA gene expression, as well as for a histological study. The results showed a significant rise in VEGF gene expression levels, as well as the presence of histological alterations in the G1 group characterized by clear congestion of graffiti follicles and necrotic lesions. with decrease in the number of primary, secondry and graafian follicles as co...
Ahmad Ibrahim Jalali1, Mudssar Ali1*, Hafiz Mohkum Hammad2,4 and Fawad Zafar Ahmad Khan1,3
...ments (field recommended doses) as compared to the plots managed using biorational approaches. Among biorational options, the yield of sand and mango wood ash mix showed a higher yield. The current evidence is useful for integrating biorational options into fall armyworm management, especially for smallholders.

...

Shimaa R. Hamam, Reham A. El-shafei, Nani N. Abdelaziz, Magdy S. Amer

...ree groups received oral doses of ibuprofen (40 mg/kg/day), ginseng (500 mg/kg b.wt/day) with ibuprofen (40 mg/kg/day), and sandalwood oil (100 mg/kg b.wt/day) with ibuprofen (40 mg/kg/day) for a total of 14 days. Serum samples were taken one and two weeks post-dosage to measure levels of testosterone, luteinizing hormone and follicle stimulating hormone. Furthermore, samples from the testis, epididymis, and seminal vesicles were taken at the second week of tr...

Eslam F.M. Eisa1, Bardees K. Elgohary1*, Mahasen El Shair1, Hagar F. Gouda2, Ali E. Kandeel1

...the effectiveness of low-dose ketamine in minimizing the cardiorespiratory depression caused by propofol and sevoflurane in spontaneously breathing dogs during laparotomy remains uncertain. This study aimed to investigate the effects of low-dose continuous ketamine infusion to mitigate the hemodynamic fluctuations associated with propofol, sevoflurane, and surgery. Therefore, sixteen healthy male dogs were randomly divided i...

Safaa El Bialy1*, Nabil Bker2, Hossam Ibrahim3, Saber, A. Saad4, Eman Ali5

...status, the results were dose-dependent, showing that higher concentrations of PEO, especially 3%, led to greater reduction percentages. The highest reduction, reaching 100%, was observed in the counts of Enterobacteriaceae and coliforms. The study concluded that using parsley essential oils at varying concentrations, particularly at 3%, could extend the shelf life of fish up to 8 days during refrigeration, specifically due to to their antioxidant and antibact...

Soumia Ed-Day1*, Meryam Laanaya1, Chaimae El Kourchi3, Radia Elgui1, Fatima Ezzahra Kacimi2, Latifa Didou1, Samira Boulbaroud2, Hicham Harhar3, Fatima-Zahra Azzaoui1

...by gavage) the following doses: 2.5, 5, 25, 50, and 250 mg/kg of the ethanolic extract, while the control group received distilled water. Biochemical, histological, and behavioral assessments were conducted at the end of the experiment. Results: In the acute oral toxicity test, the extract did not produce any signs of toxicity or mortality underscoring the safety profile of the diverse doses administered in this study. Bioch...

Dheyaa Ali Aljuhaishi*, Firas Hussain Kadim Albawi 

...ulated with E. coli at a dose of 0.5 ml containing 7.5x106 CFU/ml and were treated with bacteriophage (3.2×108PFU/g) through feeding. In the G2 group, chicken were orally inoculated with E. coli at a dose of 0.5 ml containing 7.5x106 CFU/ml and were treated with enrofloxacin 100mg/kg and neomycin 200mg/kg orally through drinking water. In the group G3, chickens were orally inoculated with E. coli at a

Mohamed T. A. Soliman1, Hadeer M. Shosha2, Hala M. Ebaid2, Heba Nageh Gad El-Hak2, Heba M.A. Abdelrazek3*

...groups were administered doses 36.75 mg and 73.5 mg of COC from the 6th day of gestation until the 20th day of gestation. The immune system of the male progeny was assessed detecting the levels of interleukins (IL-2 and IL-6) and immunoglobulins (IgG and IgE). The total antioxidant capacity (TAC) and total oxidative status (TOS) were assessed. The spleen and thymus were preserved for histopathological and ultra structural analysis. The male offsprings, who wer...

Eman Wahsh1, Tarek M Ibrahim2, Mirna E. ElAwady3*

...were evident at the high dose level as measured by increase in licks and shocks.
 
Keywords: Anxiety, Nifedipine, Propranolol, Caffeine
...

Kamal Ahmed El-Shazly1, Amira Abd El-Latif1, Nagwa Elhawary2, Asmaa F. Alswaf1, Foad Farrag3, Samy Sayed4, Mohamed El-Sharnouby5 and Mustafa Shukry6*

...xture of cashew oil at a dose of 1ml and toltrazuril 1.25ml/liter drinking water. On the 15th the oocysts of the Eimeria tenella parasite were implanted orally into all but the negative control groups. According to the current findings, G2 demonstrated a significant increase in feed conversion rate, oocysts count, lesion score, mortality rate, count total leucocytic, ALP, ALT, AST, total bilirubin, creatinine, urea, uric acid, and MDA level, the body weight si...

Heni Suryani1, Sri Novianti2*, Fatati2, Jul Andayani2, Saitul Fakhri2, Muhammad Ambar Islahudin3

... to identify the optimal dose of Binahong extract as a feed additive in a ruminant diet, using nutrient degradation and fermentation in the rumen as indicators. A completely randomized design with 4 treatments and 4 replications was employed, involving binahong extract levels: control, 1%, 1.5%, and 2% based on dry matter (DM). One gram of feed substrate, supplemented with binahong extract, was incubated in buffered rumen fluid at 390C for 48 hours in a 120 ml...

Nbaa Mutea Abid AL-Alh1, Nuha Hatem Khalaf1, Nagam Khudhair1*, Ahmed Khalid2

...s administered orally at dose 2 mg/kg of body weight. The rats dosed CPZ were divided as follows: G2 a positive control group, received CPZ alone. G3 was given an ethanolic extract of costus at a dose of 1.5 mg/kg, and G4 was administered an ethanolic extract of costus at a dose of 3 mg/kg. G5 was administered an ethanolic extract of costus plant at a

Zainab Sadik Chetheer*, Aseel Abdullah Ibraheem

...omnifera supplement at a dose of 500 mg/kg B.W., while the third group received PTU at a dose of 100 mg/kg B.W. and finally the forth group T2 was received both PTU and Withania somnifera supplement. Blood samples were collected at the start (zero time) and at the end of the study after 30 days for analysis. The animals were euthanized to obtain the thyroid gland for histopathological study. The results showed the thyroid ho...

Mariam Ismail Ali1*, Rania Helmi Abdou1, Mary Ayad Sargious2, Omnia Mohamed Khattab2, Kawthar Abdelwahed Elhady1

...ffects of bee venom at a dose of 2mg/kg against cadmium chloride hepatotoxicity, nephrotoxicity, and neurotoxicity in rats. The study found that cadmium treatment in rats increased inflammatory markers (TNF-α 264.3% and IL-1β 170.7%), and oxidative markers(MDA 140.5%), Higher liver enzymes, histopathological lesions, and genes expression screened for hepatotoxic effects. Bee venom effectively reduced inflammation (TNF-α 49% and IL-1β 41.4...
Abrar ul Haq1, Shusheng Yin2, Amara Maryam1, Muhammad Khan1*, Hafiz Abdullah Shakir1, Muhammad Akhtar Ali3, Muhammad Irfan4, Muhammad Faisal Maqbool1 and Yongming Li2*
...stant Hey-T30 cells in a dose-dependent fashion. Using Molecular docking study, we found that lathyrol exhibits strong binding interactions with STAT3 DNA binding domain through hydrogen bonding and hydrophobic interactions with various amino acid residues of STAT3. Using immunoblotting, we found that lathyrol did not inhibit STAT3 phosphorylation and dimerization. Moreover, we showed that lathyrol induces apoptosis as evident from a remarkably increased expre...

Shireen Ali Hasan1*, Ahlam A. Al-Rikaby2, Maitham Ali Al-Rikaby3  

...udied parameters in both doses (low and high). After 45 days, there was body weight gain and significantly increased level of malondialdehyde (MDA) which was accompanied by a significant elevation in blood glucose, TC, TG and LDL-c. However, a significant reduction in the level of HDL-c was noticed. Additionally, a significantly increased activity of liver enzymes of ALT, AST and ALP were observed after 45 days of treatment at both dos...

Sherine Abbas1, Hadeer M. Shosha2, Hala M. Ebaid2, Heba Nageh Gad El-Hak2, Heba M. A. Abdelrazek3*

...e (CMC) via gavage, high-dose group (73.5 mg/kg) of CO was given by gavage 1/20 LD50 of CO mixed with CMC, and a low-dose group (36.75 mg/kg) of CO was given by gavage 1/40 LD50 of CO mixed with CMC. The administration of the CO began on the 6th day gestation day and continued orally until the 20th day of gestation. Thirty days after birth, blood, and organ samples, including liver and kidney, were taken from both male and f...

Sherine Abbas1, Heba M.A. Abdelrazek2*, Eman M. Abouelhassan3, Nayrouz A. Attia4, Haneen M. Abdelnabi4, Seif El-Eslam E. Salah4, Abdelrahman M. Zaki4, Mohamed A. Abo- Zaid4, Nadia A. El-Fahla5

...ggestion to estimate the dose dependent effect of prenatal neem extract exposure. 
 
Keywords: Hematology, Immunity, Neam, Prenatal, Lymphoid depletion
...

Bassant Mahmoud Emam1, Jehan Abd Elrazek Hassanen1, Abeer Gaffer Ali Hassan3, Azza Mahmoud Abdullah1, Hadeer Said Aboelnaga2, Amina Ali Dessouki2*

...SP (100mg/kg, b.wt). All doses were daily administered by stomach tube for 8 weeks. Serum biochemical analyses of insulin, glucose, lipid profile, and liver function tests, besides histopathological analyses for the liver and pancreas, were performed. The FSE or FSP and DAPA treatment ameliorates the measured parameters in diabetic rats compared to diabetic rats: Significantly (P≤0.05) elevated body weight and insulin levels, reduced glucose, and improved l...

Ashraf B. Said*, Ibrahim A. Ibrahim, Hoda I. Bahr, Marwa A. El-Beltagy

...injected with STZ single dose (25mg/kg b.w/i.p) for T2DM induction. The diabetic one was allocated to 6 groups (10 each) based on their treatment: untreated group, metformin (Metformin HCl, 500mg/kg b.w/day), GLP-1 (Trulicity,1.5mg/kg b.w/week), BM stem cells (IV injected with 1x106 units/once), GLP-1 plus metformin and the last group BM stem cells plus metformin for 4 weeks. After 4 weeks, rats were sacrified, blood samples are collected to measure FBG, FINS,...

Advances in Animal and Veterinary Sciences

November

Vol. 12, Iss. 11, pp. 2062-2300

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