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Mono- and Mixed Invasions of Socially Dangerous Nematodes toxocara Canis and Ancylostoma caninum in Dogs in Rural and Urban Settlements in the Region North Caucasus and the Results of Tests Against them of New Drugs

Mono- and Mixed Invasions of Socially Dangerous Nematodes toxocara Canis and Ancylostoma caninum in Dogs in Rural and Urban Settlements in the Region North Caucasus and the Results of Tests Against them of New Drugs

Zarema Alimsultanova Magomedova1*, Kheda Khalitovna Dadaeva1, Roza Said-Akhmedovna Zakhkieva1, Khasan Khamitovich Shakhbiev1, Boris Kazievich Laipanov2 

1Department of Physiology and Anatomy of Man and Animals, Veterinary Medicine and Zoo engineering , Federal State Budgetary Educational Institution of Higher Education “Chechen State University”, Grozny, Russia; 2Department of Parasitology and Veterinary Sanitary Expertise, Moscow State Academy of Veterinary Medicine and Biotechnology named after K.I. Scriabin, Moscow, Russia.

*Correspondence | Zarema Alimsultanova Magomedova, Department of Physiology and Anatomy of Man and Animals, Veterinary Medicine and Zoo engineering , Federal State Budgetary Educational Institution of Higher Education “Chechen State University”, Grozny, Russia; Email: [email protected] 

ABSTRACT

In the constituent entities of the Russian Federation, the most common nematodes of a zoonotic nature are toxocarоsis and ankylostomоsis, which occur in dogs in rural and urban settlements with an EI of 70%. The aim of this work is to study nematodes in dogs in rural and urban settlements of the North Caucasus and test new drugs: tableted Helmicide F, powder Fenbental 50% and Mebentfen powder 50% for the treatment of intestinal nematodes. Studies have shown that nematodes of a zoonotic nature in dogs in the form of mono- and mixed invasions are widespread in the regions of the North Caucasus (KBR, CHR, KCHR) with a total EI of 44-68%. Associative invasion of intestinal nematodes (Toxocara canis and Ancylostoma caninum) was observed mainly in rural settlements with EI = 36.0%. in urban settlements with EI = 24.0%. In the group of dogs infected with the mixed invasion of Toxocara canis and Ancylostoma caninum, the new tableted Helmicide F at a dose of 70 mg / kg of body weight had EE and IE - 100%, Fenbental 50% powder 50% at a dose of 75.0 mg / kg body weight on ADV, once had EE and IE - 100%. The new composition Mebentfen 50% powder at a dose of 70 mg / kg of live weight, once mixed with minced meat, is highly effective (EE and IE - 100%) in experiments and is recommended for the treatment and prevention of associative invasions of intestinal nematodes. T. canis. and A. caninum in dogs. 

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The Journal of Advances in Parasitology

December

JAP Vol. 10, Pages 1-29

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