Pyometra Treatment in Bitches with Different Protocols
Pyometra Treatment in Bitches with Different Protocols
Sulake Fadhil Al-Zubaidi1*, Ghusoon A.A. Alneamah2, Ali Saleh Mahdi1, Abdulraheem Abduljalil Wali3
ABSTRACT
The focus of the present study was to evaluate various methods of treatment of pyometra in bitches. For this purpose, the study was conducted in a private clinic and veterinary hospital in Baghdad. The study included seventeen different breeds bitches. The ages of bitches range from 12-132 months with an average of 38 months. Bitches are diagnosed with pyometra (open and closed) depending on clinical signs, ultrasound, and complete blood count (CBC). Bitches were allocated into four groups: Group I: five bitches received only Aglepristone (Alizin®) given at 10 mg/kg Sc. Group II: four bitches received Aglepristone (Alizin®) was given at 10 mg/kg Sc and PGF2α at 1 mcg/kg B.W. after vaginal discharge appeared and continue until discharge disappeared. Aglepristone was repeated after 24 hours and seven days if needed for groups I and II. Group III: six bitches with open pyometra received Misoprostol (Cytotec®) given intravaginally as 200 mcg/bitch. All groups received a course of antibiotics. Group IV: two bitches treated by ovariohysterectomy under general anesthesia. Bacterial isolation was made on chromogenic agar to identification of bacteria associated with pyometra. In group I after 24 hr. from giving Aglepristone there was vaginal discharge, in some cases, we need to give a second dose of Aglepristone to bitch. In group II, PGF2α was injected after pus came out from the vulva, there was a rapid evacuation of pus from the uterus in comparison with group I with many side effects such as tachycardia, panting, and hypersalivation. In group III Misoprostol was used intravaginal, and evacuation of pus was seen after 1 hr. from administration, the evacuation was more than in groups I and II without side effects such as tachycardia and increased panting that occurred in group II. In group IV recovery occurred after surgery. E -Coli and Enterococcus were the most dominant bacteria in bitches with pyometra. We concluded that combined Aglepristone with PGF2α effectively treated pyometra in bitches. Misoprostol also increased uterine contractions with quick evacuation of uterine content.
Keywords | Bitches, Pyometra, Aglepristone, Misoprostol, PGF2α, Different protocols
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January 2024
Vol. 12, Iss. 1, pp. 1-193
