Potential Impact Microplastic Polyethylene Terephthalate on Mice
Potential Impact Microplastic Polyethylene Terephthalate on Mice
Marchel Putra Garfansa1, Roy Hendroko Setyobudi2, Iswahyudi Iswahyudi1, Shazma Anwar3,
Damat Damat2,Tony Liwang4, Mardiana Sri Susanti5, Diah Hermayanti2*, Meddy Setiawan2,
Thontowi Djauhari Nur Subchi2, Dewi Mariyam6, Yolla Muvika Ananda2, Satriyo Krido Wahono7,
Adil Basir8, Musrif Musrif9 and Anwar Saeed Khan10
ABSTRACT
Microplastic (MPs) pollution is an increasing global problem, creating deep concerns regarding its potential impact on human health. Numerous experiments have been conducted on living organisms to investigate the dispersion patterns of MPs. Furthermore, the extent of distribution and research conducted on MPs about mice still needs to be improved. This study aimed to determine the impact of PET (polyethylene terephthalate) MPs on mice’s weight, feces, and appetite. Four feed experiments, P0 (pellet BR1), P1 (potato from Pujon Farm), P2 (potato mixed 300 µg PET), and P3 (potato mixed 600 µg PET), were investigated in this research. PET MPs at a dose of 600 µg had the worst impact on mice compared to the others. There were changes in eating performance, body weight, and mice feces in treatment P1 due to the MPs contained in them. Another consequence is anticipated: A reduction in microbial diversity in the intestines of mice, resulting in a fall in both feces and body weight of the mice.
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July 2023
Vol. 39, Sp. Iss. 1
