G.E. Odo1*, E.J. Agwu1, N.I. Ossai2, C.O. Ezea3, J. Madu1 and V. Eneje2
... 0.005) in the values of malondialdehyde, catalase, superoxide dismutase, reduced glutathione, alkaline phosphatase (ALP), alanine aminotransferase (AST) and aspartate aminotransferase (AST). Similarly, aluminium phosphide enhanced levels of AST, ALT and ALP as both concentration and time dependent in elevation were recorded when compared to the control. The use of aluminium phosphide in agricultural fields near water bodies should be strongly monitored in vie...
Asmatullah Kaka2, Wahid Haron1,*, Rosnina Yusoff 1, Nurhusien Yimer1, A.M Khumran1, Akeel Ahmed Memon2, Kazhal Sarsaifi1 andMahdi Ebrahimi3
...e integrity, morphology, malondialdehyde (MDA), fatty acid composition and super oxide dismutase (SOD). Sperm characteristics such as sperm motility, viability, morphology, membrane integrity, and acrosome integrity were decreased in treated groups. DHA concentration was increased in all supplemented groups. Whereas ALA decreased in all groups except at 5ng/ml DHA was increased linearly by increasing supplementation of fatty acids. In conclusion, combination o...
Zia-ur-Rehaman1, Naila Chand1, Sarzamin Khan1 and Rifat Ullah Khan2,*
... in TN zone, while serum malondialdehyde (MDA) was significantly (P< 0.05) higher in HAT zone. No significant differences were recorded in serum antibody titer against ND, PON1 and MDA among different broiler strains in TN zone, while in HAT zone, Ross and Arber Acer showed significantly (P<0.05) higher serum antibody titer against ND. In HAT zone, significantly (P< 0.05) lower serum MDA was found in Ross and Arber Acer. Based on these results, it was...
Zhiping Hu, Hussain Ahmad, Jingfei Zhang, Lili Zhang and Tian Wang*
... capacity was higher and malondialdehyde content was lower in T1 group than that of CON group at 21d. Serum glutathione peroxidase enzyme activity was significantly increased in T1 group compared to CON group at 42d. Malondialdehyde content of liver in T1 group was lower than that of CON group. These results suggested that dietary supplementation of 10 mg/kg natamycin had a positive influence in broilers.
...
Tünay Kontaş Aşkar1,*, Şinasi Aşkar1, Olga Büyükleblebici2 and Murat Güzel3
...leishmaniasis, levels of malondialdehyde, total antioxidant capacity, glutathione, nitric oxide, myeloperoxidase, adenosine deaminase and cytokines (TNF-alpha, IL-1β) were determined and compared with the healthy controls. Significantly high levels of plasma malondialdehyde, nitric oxide, myeloperoxidase, adenosine deaminase and cytokines and significantly low levels in total antioxidant capacity and glutathione levels ...
Şaban Çelebi
...ast muscle. In addition, malondialdehyde (MDA) concentration and enzyme activities of glutathioneperoxidase (GSH-Px), superoxide dismutase (SOD) and catalase (CAT) in liver, heart, breast and thigh tissues of laying hens were determined in present study. A total of 96 White Lohman laying hens, aged 24 weeks, were randomly divided into 4 groups (n=24), each of which was composed of 6 subgroups. The control group received the basal diet (T-1), treatment groups w...
Zeynep Soyer Sarıca1*, Meryem Eren2 and Meryem Senturk2
Chukwuemeka Calistus Okolo1*, Ikenna Onyema Ezeh2, Chinelo Nnenna Uju3 and Nwakaego Ernestina Nweze1
...ls as group D. The serum malondialdehyde and catalase levels were similar in groups A--D. Therefore, treatment with the probiotics, while enhancing clearance of trypanosomes did not improve the antioxidative and clinical outcome of the infection. ...
Nouf Alharbi*, Mai Elobeid and Promy Virk
...(SOD) activity in liver, malondialdehyde (MDA) levels in liver and serum, and histopathological evaluation of liver and kidney. Results showed that low dose of quercetin was significantly (p≤0.05) more effective than the high dose. Low dose was more efficacious in reducing Cd accumulation in the tissues, reversing the effects of Cd toxicity on blood profile, and on the CAT and SOD activity in the liver and decreased the MDA levels in both serum and liver. T...
Qi Ren, Shufeng Sun, Chen Niu, Yuhong Li, Yingzhi Chong, Biao Li, Guoying Zheng and Fumin Feng*
...dismutase test kit and a malondialdehyde test kit. Genomic DNA and RNA were extracted from cells; Methylation was inhibited by treating HL7702 cells with 5-aza-2’-deoxycytidine (AZA), and the level was analyzed via the methylation-specific PCR (MSP) methods. The increases in the methylation rate of CpG islands in the CYP1A1 promoter region and expression of DNA methyltransferases (DNMTs). And then the CYP1A1 mRNA and protein expression decreased with cel...
Mo Chen1, Shad Mahfuz1, 2, Yan Cui1, Liying Jia1, Zhongjun Liu3 and Hui Song1, 4*
Sibgha Noreen*, Sumrina Faiz, Muhammad Salim Akhter, Kausar Hussain Shah
Kadry A. El-Bakry1, Lamiaa E.M. Deef1*, Lotfy Z. Habbak1 and Samia S. El-Naeli2
...increases serum level of malondialdehyde (MDA) but decrease the activity of superoxide dismutase (SOD) enzyme. On the other hand, in patuilin injected rats and treated with ginger, the activity of ALT, AST and SOD were improved and level of MDA was decreased significantly. The liver and kidney tissues showed markers of improvement after treatment the patulin rats with ginger. In conclusion, treatment with ginger can protect liver and kidney form the toxicity i...
Elmas Ulutaş1,*, Abdullah Eryavuz2, Aziz Bülbül2, Abdur Rahman3,*, İsmail Küçükkurt4 and Cangir Uyarlar5
...d (p<0.05) leptin and malondialdehyde concentration while other parameters remained unaffected. No difference was observed in ruminal pH between the treatment groups. Ruminal ammonia and number of protozoa were decreased (p<0.05) with 700 ppm and 1000 ppm zinc supplementation. Rumen Zn concentration increased (p<0.05) in the goats fed with 1000 ppm zinc, whereas there was no difference in rumen Fe and Cu concentration among the treatments, except for ...
Abdüssamet Aydın1 and Ş. Canan Bölükbaşı2*
...of yolk, the contents of malondialdehyde (MDA), superoxide dismütase (SOD) and glutation peroxidas (GSHPx) in serum. Sixty Lohman LSL white layers, 40 weeks of age, kept in individual cages were assigned randomly to five treatment groups, each group included 12 hens. The hens received one of five diets with 0, 32.5, 65 or 130 mg/kg pennyroyal extract and 50 mg/kg BHA, respectively. Experiment lasted for 60 days. At the end of the experiment, the supplemen...
Ju Zhang1,2, Dong-Sheng Jia3, Shi-Hao Zhao1,2, Xiao-Liang Xie3, Hong Chen4 and Hai-Feng Li4,*
...at-stress survival rate, malondialdehyde (MDA) content as well as superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx) activities.We observed that HGQ exerted little effect on the growth of wild-type N2 nematodes at concentration < 0.6 mg/ml, and 0.05 mg/ml of the HGQ significantly prolonged the lifespan and reduced the lipofuscin level in N2 nematodes. However, the HGQ failed to influence the pharyngeal pumping rate in N2 nematodes o...
Derya Kocamaz* and Elif Oruc
...overy period, EROD, GST, malondialdehyde, estradiol/testosterone levels were found to be lower than the control. In the pesticide mixture group, the activity of antioxidant enzymes was highest and the level of hormones was lowered. The group of the mixture pesticide showed the highest lipid peroxidation and protein carbonylation than only thiamethoxam or λ cyhalothrin exposure. In conclusion, the mixture of the insecticides showed a more toxic effect on...
Ahmet Ozer Sehirli1,2, Serkan Sayiner3*, Ayliz Velioglu-Ogunc4, Nedime Serakinci5, Emel Eksioglu-Demiralp6, Berrak Yegen7, Feriha Ercan8 andGoksel Sener2
...ssue luminol, lucigenin, malondialdehyde (MDA) and glutathione (GSH) levels. A significant difference was determined between the CRF group and the control group with regard to heart rate, blood pressure, serum creatinine, BUN, LDH, cytokines and urinary electrolyte levels. Furthermore, monocyte and neutrophil apoptosis, tissue luminol, lucigenin, malondialdehyde and collagen levels were found to increase. Tissue glutathione ...
Xuhui Zhang1, Zhiyuan Sun2, Jinfeng Cai1, Guibin Wang1, Zunling Zhu1, Linguo Zhao3 and Fuliang Cao1,*
... total cholesterol (TC), malondialdehyde (MDA) in serum and hepatic reactive oxygen species (ROS) in FR groups were significantly decreased compared with the control or NF group at 42 d of age. Furthermore, serum total superoxide dismutase (T-SOD) activity of birds from group FR3 was significantly increased (42d) compared with NF group. Additionally, the expression of antioxidant enzyme genes including nuclear factor erythroid 2-related factor 2 (Nrf2), h...
Aamir Mushtaq1,2, Rukhsana Anwar1 and Mobasher Ahmad1,2,*
.../span>) and reduction in malondialdehyde (7.83 ± 0.21 n mol/mg) level was observed in group receiving 800mg/kg of mep.a as compared to amnesic group. Pimpinella anisum thus improved memory in mice by preventing oxidative stress in brain.
...
Yuhong Li1, Dongxue Wu1, Xue Wang1, Mi Zhang1, Hanyu Zhu1, Zhe Shi1 and Fumin Feng1,2*
...ne group, the content of malondialdehyde (MDA) in each drug group gradually increased, and the activity of superoxide dismutase (SOD) gradually decreased, suggesting that oxidative stress reaction occurred in all drug groups. Compared with the baseline group, the mRNA and protein levels of NF-κB and TNF-α in the H group showed an increasing trend, and p-NF-κB and p-IκB also showed an increasing trend. However, these indicators increased...
Shaista Abbas1,Imtiaz Rabbani1, Hafsa Zaneb2, M. Shahbaz Yousaf1, Saima Ashraf2, Abid Hussain Shahzad3, M. Afzal Rashid4 and Habib Rehman1,*
... lower (P = 0.006) serum malondialdehyde (MDA) and higher (P = 0.05) thyroxine was found in yeast-supplemented goats with insignificant treatment into day interactions during postpartum period. Serum urea, total proteins, albumin, globulin, albumin to globulin ratio, triiodothyronine, aspartate aminotransferase and alanine aminotransferase remained unchanged amongst the groups during the transition period. In conclusion, dietary yeast supplementation has resul...
Haiyan Yang1, Hongxia Liu1, Wenlong Wu1*, Weilin Li2 and Lianfei Lyu1
...ydrogen peroxide (H2O2), malondialdehyde (MDA), ascorbate (AsA) and reduced glutathione (GSH), activities of superoxide dismutase (SOD) and peroxidase (POD) in leaves of ‘Hull Thornless’ were investigated. In the treatment group, water stress significantly increased EL, and the accumulation of photosynthetic pigments, protein, soluble sugar, H2O2 and MDA. After re-watering, all of those parameters showed decreases of different degree. LWC was signi...
Jin-Juan Wan, Mei-Fang Shen*, Hui Xue, Hong-Yan Liu, Mei-Qin Zhang, Xi-He Zhu and Chong-Hua Wang
...owest catalase (CAT) and malondialdehyde (MDA) were observed in crayfish fed 3 times/day. However, there were no significant differences in cortisol, glucose (Glu), and superoxide dismutase (SOD) among all groups (P>0.05). The cumulative mortality in F3 was significantly lower than that of the other groups at d4 after challenge (P<0.05). In conclusion, both low and high feeding frequencies could cause stress of juvenile Procambarus <...
Muhammad Rashid, Mahmood Ahmad Sajid, Nosheen Noor Elahi, Sibgha Noreen and Kausar Hussain Shah*
...O2) and malondialdehyde (MDA) were improved in all three wheat varieties but this increase was relatively lower in variety F23. The superoxide dismutase (SOD), peroxidase (POD) and catalase (CAT) activities were improved in all wheat varieties in a water shortage. The variety F23 exhibited higher antioxidants levels which are positively associated with its potential of drought stress tolerance. This study provided a helpful understanding of th...
Nashwa M. Helmy1, Ahmed S. Ahmed2, and Zeinab3 Y. Mohamed
...ults of antioxidant both malondialdehyde (MDA) and catalase enzyme (CAT) showed significant increase while level of gloutathion (GSH), total antioxidant capacity (TAC) and gloutathion peroxidas (GPX) showed significant decrease in infected cattle. Conclusion: Sero-survey, conventional techniques and PCR assay should be applied besides clinco-pathological for any cases with skin lesions as early as possible to diagnosis and apply adequate control measures. The ...
Mengke Wang1, Shucheng Huang2, Cai Zhang1*, Haizhou Gong1,
Shunan Cuan1, Shuaishuai Wang1, Qi Shao1, Wenhao Xu1, Sudan Meng1,
Pengfei Li1, Yuqin Wang1 and Zijun Yang1
...nd the concentrations of malondialdehyde (MDA) were reduced in MAG groups, yet the differences were not significant (p>0.05). Notably, Liver weight, liver index, and triglyceride (TG) content were diminished significantly compared with the control group (p<0.05). These results demonstrated that supplementation of MAG to drinking-water of layers can enhance the antioxidant capacity, improve lipid metabolism and has a protective on liver injury, while ...
Congfen Zhang1,Yingxiao Liu2, Linfeng He2, Fengjun Shi2, Weitang Yao2 and Xuegang Luo2,*
...12.5mM, 25mM. Changes in malondialdehyde (MDA) and reduced glutathione (GSH) and activities of superoxide dismutase (SOD), and catalase (CAT) as well as their corresponding mRNA levels in the fat bodies of the pupae were evaluated. As a result, we found that the contents of MDA were increased at 4 h and then decreased compared with control. And, the contents of GSH were decreased gradually. However, the activities of catalase were inhibited and the trend of SO...
Arkan B. Mohammed*, Ammar S. Abdulwahid, Samah M. Raouf
...ne, while, decreased the malondialdehyde, AST and ALT activity in comparison to the control. Therefore, it can be concluded that thyme additives can be used in laying hens diet to improve egg production, egg quality, antioxidant and biochemical parameters in a dose-dependent manner.
Keywords | Antioxidants, Egg production, Laying hens, Thyme
Elfadil Elfadul Babiker1, Khalid Ahmed Abdoun2*, Fahad AL Juhaimi1, Kashif Ghafoor1, Riyadh Salih Aljumaah2 and Ahmed Abrahim Al-Haidary2
...d serum concentration of malondialdehyde (MDA) by > 45% compared with AHD-fed animals. Reductions in the serum concentrations of glucose by 14 to 41%, and that of cholesterol by 18 to 40% were observed in animals fed on Moringa-supplemented diets. It is worth mentioning that MOD supplementation showed the greatest positive effect on all tested blood parameters. The results of the present study indicate the importance of dietary supplementation of Moringa on...
A.M. Abdul Azeem, Ashraf M. Mounir and Amr N. El-Shahat*
...t glucose and testicular malondialdehyde serum level and the activity of xanthine oxidase were elevated (P < 0.05) with obvious reduction in the concentration of insulin, total thyroid hormones triiodothyronin and thyroxine, leutinizing hormone, testosterone and testicular antioxidant parameters (glutathione content , the activity of xanthine dehydrogenase, superoxide dismutase and catalase) in the group of alloxan (150 mg/kg B.WT)-administrated rats as com...
Chunjie Song1, Shangquan Gan2 and Xiaoyun Shen1,3*
...ood urea nitrogen (BUN), malondialdehyde (MDA), and the number of white blood cell (WBC) in 3 drug delivery groups were extremely significantly lower (P<0.01) than the control group, and the contents of potassium (K), total protein (TP), albumin (ALB), globulin (GLB), and total antioxidant capacity (T-AOC) in the 3 drug delivery groups were extremely significantly higher (P<0.01) than that of control group, but there were no remarkable differences betwee...
Syukriah Syukriah1, Ulinnuha Nur Faizah2, Hendry T.S. Saragih3*, Rizki Fitrawan Yuneldi4, Soenarwan Hery Poerwanto5, Raden Roro Upiek Ngesti Wibawaning Astuti5, Stephan Immenschuh6
Fujun Miao1, Chunlan Shan2, Wei Yang3, Hao Wang3, Shuxiang Geng1 and Delu Ning1*
...reasing the liver index, malondialdehyde (MDA) contents, and the expression levels of F4/80. The expression levels of key factors in the toll-like receptor 4 (TLR4)/nuclear factor-κB (NF-κB) signaling pathway reduced significantly after feeding with walnut oil to the ALD mice. Walnut oil may exert a protective effect on ethanol-induced ALD in mice by inhibiting the TLR4/NF-κB signaling pathway....
Hong Yin*, Dan Yang, Ji-Jie Liu, Jing-Wei Ding and Dan-Dan Cui
...ase (GPx) activities and malondialdehyde (MDA) level were significantly increased in liver tissues with β-CM-7 treated. β-CM-7 decreased the fatty acid synthase (FAS) level significantly. The results suggest that β-CM-7 can change the dyslipidemia which is induced by aging. The mechanisms of the regulating effects likely tend to pass through controlling the oxidative stress and balancing the level between FAS and acetyl-CoA carboxylase (ACC).
Semra Okur Gumusova1, Gul Fatma Yarim2, Cuneyt Tamer1,*, Ayris Salt2 and Gokhan Inat3
...ase (GPx) activities and malondialdehyde (MDA) concentrations were measured by the spectrophotometric methods. Data obtained revealed higher MDA levels in IPNV infected cells than negative control medium (p<0.001). However, SOD and GPx levels in IPNV infected cells were lover than negative control cells medium (p<0.001). These results indicate that, cell damage in RTG-2 cell line, that is caused by IPNV is assosiated with oxidative stress....
Mohamed Abd El-Fattah Abo-Farw1, Maged Ahmed Aboul-Omran1, Abdel-Khalek El-Sayed Abdel-Khalek2*
...creased (P<0.0001) in malondialdehyde (0.80±0.043 vs. 1.68±0.064 mmol/ml). Mastitis significantly decreased serum concentration of progesterone (P4), estrogen (E2), thyroxin (T4), zinc (Zn), and selenium (Se) by about 24.05, 13.80, 5.36, 2.50, and 3.44%, respectively, while triiodothyronine (T3) concentration showed non-significant decrease by about 3.77%. Mastitis incidence at early postpartum in lactating Egyptian buffaloes delayed the resum...
Amira M. Refaie1*, Manal S. Mohamed1, Enayat H. Abo El-Azayem1, Sherein H. Mohamed2
A. Samy1*, H.M.A. Hassan1, Fatma T.F. Abd-El Ghany2, Shama H. Morsy2
...(P>0.05) decreased in malondialdehyde of all treatments compared to the control. Also, there is no any negative effect on the thyroid hormones with any treatments compared to the control. These results suggested that rabbits fed diets enriched with curcumin or garlic extract could have better performance, carcass characteristics, and antioxidant status compared to the control.
Keywords | Curcumin extract, Garlic extract, Growing rabbits, Antioxidant...
Alaa Jaheen*, Noha Salem, Mohamed El-sherif
...ioxidant capacity (TAC), malondialdehyde (MDA), C-reactive protein (CRP), serum zinc, copper concentrations, total protein, albumin, globulin values, triglycerides, and cholesterol concentrations. The most consistent hematological alteration was elevated eosinophils in eczema-affected horses. The oxidant-antioxidant status showed a significant increase in malondialdehyde with a significant decrease in total antioxidant capac...
De Hu, Jia Wang, Huan Wang, Xiang-Yang Leng, Tian-Yi Zhao* and Shu-Min Wang*
...eroxide dismutase (SOD), malondialdehyde (MDA), nitric oxide (NO) in gastric tissue and the levels of tumor necrosis factor (TNF–α) and interleukin (IL-6) in serum were measured through ELISA, and the contents of NLRP3, ASC, caspase-1 and IL-1β in gastric tissue were detected by Western blot. The results showed that FP of C. lilacina could effectively prevent the stress gastric ulcer induced by WIRS in mice by reducing the expression level of ...
Ikele*, Chika Bright, Ujunwa Aghaji, Mgbenka, Benard Obialo
...tathione peroxidase, and malondialdehyde activities in the gill were between day 14 and 21. Significant levels (p<0.05) of floc volumes (67.33 to 72 ml) were obtained from the total suspended solids maintained between 111 to 324 mg/L. Total heterotrophic bacteria present in the biofloc media were higher in CA 20:1 with a significantly peak value of 390X104 cfu/ml compared to other groups. The C:N at 10 and 20 utilizing cassava and wheat supported growth of...
Feng Xu, Weijing Fan and Guobin Liu*
...xide dismutase (SOD) and malondialdehyde (MDA) were measured using commercial kit, and expression levels ofNEXN-AS1 and miR-410-3p were detected using real-time quantitative PCR analysis. The dual luciferase experiment was applied to verify the targeted relationship betweenNEXN-AS1 and miR-410-3p. HUVECs were transfected with NEXN-AS1 overexpression vector, and then treated with ox-LDL for 24 h before detecting the activity, apoptosis rate and oxidative stress...
Asmaa Khamis1, Osama Abdalla1, Mohamed Hashem2, Noha Abdelnaeim1*
...thered for estimation of malondialdehyde (MDA), antioxidants, apoptotic markers, cytokines, and histopathological changes. Our results revealed a significantly increased MDA, caspase-3, p53, tumor necrosis factor-α, interleukin (IL)-1β, IL-18 and, IL-10, and a significant decline in glutathione and superoxide dismutase in the CCl4 group. However, intoxicated groups treated with PN and PM showed marked improvement in the measured parameters. Therefor...
Rawda S. Mohamed1,2, Mohammed Y. Matoock2*, Abeer H. Abdelrazek2
...tor-alpha (TNF-α), malondialdehyde (MDA), and glutathione (GSH) were measured. Mice were subjected to open field, plus maze, and dark light activity box tests. Swiss Multiple Acute concurrent Stress (SMAS) showed more responsiveness to MAS than Balb/c Multiple Acute concurrent Stress (BMAS) in most biochemical and behavioral parameters, with an elevated level of corticosterone and MDA IL-6, and TNF-α and reduced levels of GSH. In conclusion, SMAS s...
Xiaowei Huang1, Jinji Wang1, Zhun Yu2, Minghua Duan1* and Zhe Lin1*
...n serum, the contents of malondialdehyde (MDA) and superoxide dismutase (SOD) in kidney of each group were detected with ELISA after 24 h of irradiation, and the protein expression levels of TGF-β1, phosphorylated (p-)Smad2, p-Smad2, p-Smad1, p-Smad5 and BMP7 in kidney were detected by western blotting. In the results, compared with the model group, NOS, NO and MDA contents were decreased in the middle and high dose groups while SOD contents were increase...
Entesar Z. Eliraqy1*, Basant M. Shafik2, Yasser S. Hussein1, Abdelwahab A. Alsenosy3, Emad A. Abd allah1, Mohamed F. Saad1
...rlic extract reduced the malondialdehyde than control. Finally, it can be concluded that garlic extract additive to extender would be useful to improve semen quality and antioxidant enzymes of buffalo-bulls spermatozoa after different processes (cooling and freezing) at variable time.
Keywords | Plant extract, Preservation, Spermatozoa, Garlic Extender, Antioxidant enzymes.
...
Al-Hassan M. Mostafa1*, Gehan Mohammed Sayed2
...ation of Total peroxide, malondialdehyde (MDA), protein carbonyl (PC), Catalase, reduced glutathione (GSH) and superoxide dismutase (SOD). Garlic and coriander treated goats showed significant reduction of FEC as compared with control positive ones. Treated goats exhibit no changes in total peroxides while there were non significant changes of PC, MDA, Catalase and SOD, in contrast there was an obvious increase of GSH. Histopathologically, Abomasum tissue rest...
Saydat Saad Abd El-Megeed1, Walaa Yehia El-Sayed1*, Tarek Khamis2
...eduction was recorded in malondialdehyde (MDA), as well as improved catalase (CAT), glutathione peroxidase (GPx), and superoxide dismutase (SOD). A reduction was found in the gene expression in the hepatic homogenate of Patched 1, hedgehog-interacting protein (Hhip-1), smoothened (SMO), glioma-associated oncogene homolog 1 (GLI1), and extracellular signal-regulated kinases 1 (ERK1). On the other hand, there was a significant upregulation in the mRNA expression...
Aslı Çilingir Yeltekin
...eoxyguanosine (8-OHdG)), malondialdehyde (MDA), and antioxidants (SOD, CAT, GSH-Px) activity in Van fish kidney and muscle tissue after 24., 48., 72., and 96. h of tebuconazole exposure at a concentration of 2.5 mg/L. The obtained results indicated that caspase-3, 8-OHdG, and MDA levels significantly increased compared to the control (p < 0.05). The kidney and muscle tissues indicated a significant decrease in antioxidant enzyme activities (superoxide dismu...
Hemat A. Abdel Magied*, Heba H. Habib, Amany H. Waly, Ahmed Fadl, Sayed M. Shalash
...t oxidative by decreased malondialdehyde (MDA) by 28.15 and 19.87 %, respectively and improve meat quality by decreased low density lipoprotein (LDL) by 7.69 and 4.73 %, respectively. The EXP2 observed chicks fed on low ME and low CP diet significantly decreased total body weight gain (BWG) with increased in total feed intake and FCR. Chicken treated by PEP had significant increased on final body weight, BWG and improved FCR for control and L10%-100. Chicks fe...
Noha M. Abd El-Azeem*, Hemat A. Abdel Magied, Mervat N. Ghazal, Nehad A. Ramadan, Enayat H. Abo El-Azayem, Y. S. Hussein, Heba H. Habib
...n A/G ratio and decrease malondialdehyde (MDA) in the treated groups in compared to the control group. In conclusion, turmeric, MOS and Biostrong supplements had a beneficial effect as natural antioxidant additives, especially the mixture among them, by protecting against oxidative stress factors caused by pregnancy and lactation in female rabbits under heat stress.
Keywords | Antioxidant; Turmeric; MOS; Biostrong; stress; Rabbit does
...
Reda Hassan*, Bahaa Abou-shehema, Sherif Zayed, Micheal Gorgy, Shama Morsy, El-Sayed Abu El-Hassan, Mahmoud El-Gbaly, Hanaa Basuony, Ebtehal Hassan
...ly (P<0.05) increased malondialdehyde values in liver and significantly (P<0.05) diminished the reduced glutathione (GSH), glutathione S- transferase (GST). In addition to, dissemination of aflatoxin residue in broilers liver was detected. Nevertheless, dietary addition of HSCAS and SC, in separate and combined forms, alleviated the above-mentioned alterations. The combination of HSCAS with SC was more efficient than having them in a separate form.
...
Ibrahim El-Ratel1*, Mostafa El-Moghazy2, Amira El-Gaml2, Ibrahim Abu El-Naser2
... capacity, while reduced malondialdehyde in blood serum and in seminal plasma. Advanced motility, membrane integrity, livability and sperm viability were improved, but sperm abnormality, apoptosis and necrosis were reduced in cryopreserved semen by all PEE levels. Total antioxidants capacity was increased, while malondialdehyde was decreased in post-thawed semen by all PEE levels. Conception rate of doe rabbits was improved ...
Hongfeng Guo
...ling. The expressions of malondialdehyde (MDA), superoxide dismutase (SOD) and prostaglandin (PGE) in lower respiratory tract were detected by the kit; the expressions ofprotein kinase B (Akt), Bax and Bcl-2 were detected by Western blot. According to our findings after drug treatment, the body weight and respiratory ventilation of mice returned to normal level compared with the intermittent hypoxia group. Compared with the blank control group, after intermitt...
Lulu Ding, Ke Wang, Ruxue Huang, Wenjing Yu, Bingzhao Yan, Mengli Jiang and Jicang Wang*
...ls of glutathione (GSH), malondialdehyde (MDA), catalase (CAT), and total superoxide dismutase (T-SOD) were measured. Histopathological sections of the kidney were made to observe the structural damage. Results showed that the red blood cell count (RBC), hemoglobinconcentration (HGB), and hematocrit(HCT) of serum were significantly reduced after Cd exposure for 4 weeks. Cd increased the expression of GSH and MDA and decreased the activities of CAT and T-SOD. F...
Rukhsana Anwar1*, Ammara Abd-Us-Sattar1, Afifa Noor2, Kanwal Ashiq1,3 and Shah Jahan4
...dismutase, catalase, and malondialdehyde were determined in liver homogenates. The phytochemical analysis of extracts revealed the presence of many important bioactive compounds. Real-time PCR results showed that aqueous extract decreased the mRNA expression of CYP1A2, CYP3A4. The methanolic extract decreased mRNA expression of CYP2C9 and CYP3A4. Both extracts enhanced GST-specific activity, tGSH, SOD, and CAT activity in rats. It is concluded that leaf extrac...
Owolabi Olutunmise Victoria1*, Saka Olusola Stephen2, Olashinde Oluwaseun Ruth1, Alli Smith Yemisi Rufina3
Dalia Zaafar1*, Heba M.A Khalil2, Soha Hassanin3, Mohamed R. Mousa4, Mona G. Khalil1
...ral, biochemical such as malondialdehyde (MDA), reduced glutathione, superoxide dismutase (SOD), tumor growth factors, and apoptotic TUNEL assay, were evaluated after three weeks in addition to Immunohistochemical analysis was done on the proliferating cell nuclear antigen (PCNA), hypoxia-inducible factor 1-alpha (HIF-1), PPAR, and cyclin D1. Results: Mice treated with Cis+Pio HD showed higher levels of SOD, GSH, p-ERK1/2 and p38-MAPK, as well as lower levels ...
Caiping Duan
...xide dismutase (SOD) and malondialdehyde (MDA) were detected by enzyme-linked immunosorbent assay. Results showed that compared with the control group, the low-dose propofol group had increased NO, decreased ET-1 and cTnT contents (P<0.05), and high-dose propofol group had further increased NO and further decreased ET- 1 and cTnT contents compared with low-dose propofol group (P<0.05). Compared with the control group, the low-dose propofol group had redu...
Doaa H. Assar1, Rasha A. Al-Wakeel2, Zizy I. Elbialy3, Mahmoud M. El-Maghraby4, Helmy K. Zaghlool5, Adel A. El-Badawy4, Abdel-Khalek E. Abdel-Khalek6*
...icantly increased, while malondialdehyde significantly decreased in SPL groups. Based on our results, spirulina as a dietary feed additive (5 g/kg diet) could be used safely for improving growth, health, antioxidant defense system, and semen quality of growing cross-bred ram lambs from 10 to 15 months of age.
Keywords | Antioxidant, Growth, Lipid profile, Microalgae, Ram semen
...
Anhar Ibrahim Elhanafy*, Amr Mohamed Mousa, Amaal Mohamed Kamal
...BV caused a decrement in malondialdehyde and nitric oxide levels whilst it enhanced GPx activity, SOD, IgG and IgM, compared to control. Furthermore, BV treated does have significantly higher levels of C3 and C4. Conversely when compared to control, significant reduction in IL-1β, IL-6 and TNF-α was recorded. In addition, BV treatment led to a significant improvement in T3 and T4 concentrations as detected by the radioimmunoassay technique. Results ...
Amr N. El-Shahat1*, A.M. Abdul Azeem1 and Mohamed H.M. Abd el Megid2
...by reducing the level of malondialdehyde compared to HCD-fed rats. The results concluded that BLE may have an effective role in reducing high cholesterol levels....
Muhammad Rizwan1, Hamid Akbar1*, Aftab Ahmad Anjum1, Muhammad Arif Khan1, Aneela Zameer Durrani2, Muhammad Abid Hayat3, Anjum Masood4, Muhammad Talha Sajjad1 and Nadeem Raza2
...oxidative stress status (malondialdehyde, MDA; catalase, CAT), metabolic status (beta hydroxybutyric acid, BHBA; nonesterified fatty acid NEFA) and hematological changes (hemoglobin, total leucocytes, red blood cells, neutrophils, platelets, lymphocytes) in serum of dairy cows before and after the surgical correction of left displacement abomasum. Twenty-six cows were divided into two groups as control (Group-A) and treatment (Group-B), each of 13 cows. Left d...
Abdulaziz A. Alaqil*
...(BT), H/L ratio, plasma malondialdehyde (MDA), and corticosterone (CORT) concentrations were evaluated in the treatment groups (n=10). Additionally, samples of the spleen and duodenum were taken from layers in each group (n=10) to assess heat shock protein 70 (HSP70) density and glutathione peroxidase (GHS-px) activity, respectively. The general linear model procedure with one-way analysis of variance (GLM-ANOVA) was used to analyze the data. The results...
Rizki Palupi*, Arfan Abrar, Fitri Nova Liya Lubis, Yuni Kurniati, Bianca Ikriza Octa Nadia Putri
...hematological status and malondialdehyde levels in broiler chicken blood. The study was conducted experimentally with a completely randomized design, which consisted of 5 treatments and 5 replications. The treatment was the use of a combination of cassava tuber and indigofera leaves meal (70%+30%; CCI) in the ration, namely: T0 (0% CCI in the ration), T1 (5% CCI in ration), T2 (10% CCI in ration), T3 (15% CCI in ration) and T4 (20% CCI in ration). The materia...
Vui Van Nguyen1, Samorn Ponchunchoovong2, Sajeera Kupittayanant3, Pakanit Kupittayanant2*
...as also analysed through malondialdehyde production. The study found that there was a gradual decrease in all sperm quality indicators of all the treatments during 12 days of storage. In addition, the chilled sperm motility parameters among all the semen extenders were not noticeably different at each time period of evaluation (P>0.05). Although sperm lipid peroxidation index in the Ocimum gratissimum essential oils treatment was higher than those in the tr...
Walaa I. Mohameden1, Haidy G. Abdel-Rahman2, Ibrahim M. Hegab3*
...per were recorded, while malondialdehyde, TNF-α, and MMP-9 significantly (P < 0.05) decreased. Furthermore, buffalo calves showed significant ( P < 0.05) increases in both ingestive and locomotor activities, while grooming and lateral recumbency significantly (P < 0.05) declined. Mineral supplementation had a favorable effect on animal skin, health conditions, and antioxidant activity, as well as it has a minimizing influences on TNF-alpha and ...
Vui Van Nguyen1, Samorn Ponchunchoovong2, Sajeera Kupittayanant3, Pakanit Kupittayanant2*
...pectively. Additionally, malondialdehyde production was measured to evaluate lipid peroxidation capacity. The results revealed that incorporating essential oils at concentrations under 100 µg/ml in semen extenders had a positive impact on sperm quality. Nonetheless, employing essential oils at elevated concentrations of 200 µg/ml exhibited detrimental impacts on the sperm. The optimal dosage for maintaining the integrity of the dog sperm’s me...
Rusul Adnan Dawood, Hasan F.K. Alghetaa*
...antioxidant capacity and malondialdehyde levels to combat the toxic exposure of mercuric chloride (HgCl2) with or without collaboration of resveratrol (RES) supplement. Forty-five adult Sprague Dawley, 8-10 weeks old female rats weighing 170-220 g were randomly grouped as following; control group (C) kept without any medication. Dimethyl sulfoxide (DMSO) used as vehicle to prepare RES treatment was given to D-group. RES administered to R-group. Challenge group...
Abdel-Khalek El-Sayed Abdel-Khalek1*, Abdelaziz M. Sakr2, Wael M. Nagy2, Hesham S. Abou-Serie2, Entesar Z. Eliraqy2
...apoptosis, necrosis, and malondialdehyde level; most favorable results were recorded with PEE2. The foregoing results indicated that supplementation of Tris-semen extender with propolis ethanolic extender at a level of 8 mg/ml increased the functional activity of spermatozoa, decreased sperm apoptosis, and necrosis, and improved the antioxidant status of sperm medium in cryopreserved semen of Egyptian buffaloes.
Keywords | Egypti...
Weijun Chen1*, Shiyang Gao1, Ping Sun1, Xiaohui Sun2, Yongbin Wei1, Jingyang Chen1 and Jialong Chen1
...ive stress by increasing malondialdehyde (MDA) content, decreasing activity levels of antioxidant enzymes and contents of reduced glutathione (GSH). Furthermoure, diet HF significantly decreased the mRNA expression of nuclear factor erythroid 2-related factor 2 (Nrf2) and heme oxygenase-1 (HO-1), and simultaneously increased the mRNA expression of tumor necrosis factor α (TNF-α), interleukin-1β (IL-1β), and IL-6 in liver of common carp co...
Hafiz Muhammad Arsalan1, Amina Arif1 and Muhammad Khalil Ahmad Khan2*
...Biochemical profiling of malondialdehyde (MDA), superoxide dismutase (SOD), catalase (CAT), glutathione (GSH), nitric oxide (NO), advanced oxidation protein product (AOPP), advanced glycation end products (AGE’s) and micronutrients (retinol, ascorbic acid, alpha tocopherol), complete blood count, liver profile, renal profile, lipid profile, serum electrolytes were evaluated in CML and control groups. Our study reported that no significant difference in b...
Chen Zhao, Lulu Ding, Ying Ye, Congying Kou, Haoran Xiao, Jing Zhu and Jicang Wang*
...ntent of glutathione and malondialdehyde and decreased the content of catalase and total superoxide dismutase. Instead, Nar significantly attenuated these Cd-induced toxic activities. Furthermore, the protein expression levels of Beclin1 and P62 were increased in the Cd-treated group. Treatment with Nar can significantly inhibit the increase of P62 protein expression level caused by Cd, indicating that Nar has a certain inhibitory effect on cell autophagy. In ...
Imbang Dwi Rahayu1, Ali Mahmud1*, Wahyu Widodo1, Adi Sutanto1, Apriliana Devi Anggraini1, Devi Dwi Siskawardani2, Wisnu Nurcahyo3, Tri Untari3
...notransferase (ALT), and malondialdehyde (MDA). Adding herbs through drinking water gave lower TG and LDL levels than through feed or the control. The control had the lowest level of ALT, which increased along with adding 2% herbs through drinking water. Adding 3% herbs through the feed reached the highest ALT level. Adding herbs through feed and drinking water up to 3% could maintain normal blood parameters (total plasma protein, globulin, cholesterol, HDL, A...
Xiaowei Huang, Yajie Wang, Jia Zhou, Junxiu Liu, Zhe Lin and Ruili Li*
...eroxide dismutase (SOD), malondialdehyde (MDA), lactate dehydrogenase (LDH) and reduced glutathione peroxidase (GSH-Px) were detected by ELISA. The expression level of TLR4/NF-κB, and HandE staining was used to observe the renal tissue. In the results, compared with model group, the spleen index and whole blood viscosity was significantly decreased, while the thymus index, peripheral blood WBC, RBC, Hb, HCT, PLT levels, and NO, SOD, GSH-Px levels in seru...
Azza M. El-Kattawy1, Tarek Abou Zed1, Randa Megahed1 and Mohammed El-Magd2*
...s [lipid peroxide marker malondialdehyde (MDA) and nitric oxide (NO)], 6) increased the levels of antioxidant markers [reduced glutathione (GSH) and superoxide dismutase (SOD)]. These findings conclude that administration of Sim relieved pristane-induced arthritis, with best improvement in the Sim co-treated (prevention) group. Thus, Sim could be used as a protective drug against rheumatoid arthritis based on its immunomodulatory, anti-inflammatory, and antiox...
Physiological Effect of Glycyrrhizic Acid on Adrenal Insufficiency Induces by Glucocorticoid in Rats
Wafaa AL. Bnyean1,2 ,Zainab A.H. AL-Mousawi1*
...zyme (11β-HSD), and malondialdehyde were measured. The results revealed treatment with glycyrrhizic acid improved significantly (P<0.05) in serum cortisol, ACTH, CRH hormones, and (11β-HSD) enzyme concentration, while was a significant reduction in serum MDA level in the therapeutic and protective group compared with the positive control group. Our results concluded that glycyrrhizic acid improves the alteration caused by hydrocortisone of hypotha...
Mustafa M. Khalaf*, Rana A. Salih
... significantly increased malondialdehyde (MDA), liver biomarkers (ALT, AST, ALP, and TP), and prothrombin time. Otherwise, glutathione (GSH), and total protein (TP) level was substantially reduced in the control group. Studies have demonstrated quercetin’s capacity to decrease cyclophosphamide’s effects on (MDA, ALT, ALP, TP, and AST) while increasing GSH. Also, quercetin significantly affects body weight for their group and mixed group with c...
Afshan1, Asad Ullah2*, Imad Khan2, Rafiq Ullah1, Tahira Tayyab1, Fatima Syed3, Raheela Taj3, Shumaila Gul4, Faiza Khan5, Ibad Ullah Jan6, Syed Weqas Ali7 and Assad Ullah8
Ying Chen1, Chao-Zheng Li2, Zhun Yu3, Jia Zhou4, Yan Xu4, Zhe Lin4, He Lin4* and Xiao-Wei Huang4*
...eroxide dismutase (SOD), malondialdehyde (MDA), glutathione peroxidase (GSH-Px) and catalase (CAT) in myocardial tissue were detected by ELISA. Hematoxylin and eosin (HandE) staining was used to detect the histological changes of rat myocardium. Western blotting (WB) was used to detect the protein expression levels of nuclear factor erythroid 2-related factor 2 (Nrf2), heme oxygenase-1 (HO-1), and NADH quinone oxidoreductase 1 (NQO1) in rat myocardial tissue. ...
Xiao-Wei Huang1,2, Mei-Li Liu1, Jin-Ji Wang1, Yue-Xin Liu3, Zhe Lin1, Chun-Shu Rong4* and Ji-Xiang Ren4*
...eroxide dismutase (SOD), malondialdehyde (MDA), brain-derived neurotrophic factor (BDNF), and nerve growth factor (NGF) in serum were detected using ELISA. The protein expression levels of phosphoinositide 3-kinase (PI3K), protein kinase B (Akt) and mammalian target of rapamycin (mTOR) in the hippocampus were detected through western blotting. In the results, VAP contained 17 kinds of AA, including 7 essential AA, with a content of 394.08 g/kg, the total AA co...
Dan Song1,2, Ming-Juan Ge3, Jie Li1,2, Yi Jiang1, Xiu-Mei Kong1, Jiao-Jiao Xu1, Xu Ji1,2, Rui-Xin Shi1 and Qin Zhao1,2*
...eroxide dismutase (SOD), malondialdehyde (MDA), and activity of total antioxidant capacity (T-AOC), catalase (CAT) in mice liver were measured; while SOD and MDA contents and activity of T-AOC, CAT, Na+-K+-ATPase, Ca2+-Mg2+-ATPase, pyruvate kinase (PK) and phosphofructokinase (PFK) in mice brain were evaluated. In the results, G. straminea ethanol extract markedly enhanced hypoxia tolerance in mice. It attenuated hypoxia-induced oxidative stress by reducing MD...
Franciscus Rudi Prasetyo Hantoro1,2,*, Dwi Sunarti1, Turrini Yudiarti1, Sri Sumarsih1, Rini Nurhayati2
...us and spleen, levels of malondialdehyde (MDA), number of Newcastle Disease Virus (NDV) antibodies, increase in body weight, and feed efficiency. High stocking density has a significant impact on increasing the number of LAB and coliforms in the ileum, reducing the weight of the thymus, and reducing the amount of feed consumed. The lower the crude protein level, the lower the NDV antibody titres, but it did not affect the blood profile, LAB and coliform number...
Ghusoon Hasan Jadaan1*, Khalisa K. Khudair2
...nalyzed blood samples of malondialdehyde (MDA), total antioxidant capacity(TAO-C), protein carbonyl(PC), reactive oxygen species (ROS), and gamma-glutamyl transferase concentration(GGT). The results indicated that 200 mg/kg of SiO2 - NPs orally for 4 weeks contributed to a substantial drop in serum TAC-O, an increase in MDA, GGT, PC, and ROS concentration, and attenuation of silica’s oxidative stress status, CP NPs (T3) or SiO2 NPs (T2) administered oral...
Estabraq Hayder Khayoon, Ammar Ahmed Abdulwahid*
... in the concentration of malondialdehyde and decrease levels of Total antioxidant in blood serum and behavioral differences like Acrylamide greatly decreased the struggling and ascending time in the swimming test, dramatically lengthens the time needed to turn an animal’s head 180 degrees during a negative geotaxis test and decreased locomotors activity in the Y maze test. Curcumin’s anti-apoptotic, anti-inflammatory, and antioxidant properties ...
Farid S. Nassar1,2, Osama A. El-Sayed3, Saidi Ouassaf4, Ahmed O. Abbas1,2*
...orticosterone (CORT) and malondialdehyde (MDA) levels as stress markers in broilers reduced significantly (p < 0.05). On the other hand, adding FS to broiler diets considerably (p < 0.05) improved both the humoral and cellular immunity, as determined by the antibody (AB) titers and the phytohemagglutinin-wattle reaction (PHA-WR), respectively. It was observed that most of these measures showed a linear trend response to the rise in FS levels up to 30 g/k...
Khaeruddin1, Gatot Ciptadi2, Muhammad Yusuf3, Iswati4, Setya Budhi Udrayana4, Sri Wahjuningsih2*
...on. The concentration of malondialdehyde (MDA) was lower (P=0.05) with the addition of 3 mM BHT at 24 hours of storage. In conclusion, the addition of 3 mM BHT showed promising potential to maintain chicken sperm quality after liquid storage.
Keywords | Butylated hydroxytoluene, Gaga chicken, Diluent, Liquid storage, Semen, Sperm
...
Eman Said El-Hadad*, Hesham Ahmed Madian, Mahmoud A.E. Hassan, Mohamed Fahmy Saad, Abdelghany M. El-Shhat, Entesar Zakaria Eliraqy
...and IgM increased, while malondialdehyde and cortisol decreased in G2 and G3 compared with G1. In conclusion, dietary supplementation of L-arginine (0.4 g/kg) for three months improved hematology, protein metabolism, lipid profile, liver, kidney, and intestine functions, antioxidant status, immunity and welfare of Egyptian geese under heat stress condition.
Keywords | Arginine, Dietary additives, Heat-stressed Egyptian geese, His...
Peixia Yu1*, Lijun Bo2 and Xueyin Song1
...LVDP), ±dp/dtmax, malondialdehyde (MDA), superoxide dismutase (SOD) activity, creatine phosphokinase MB (CK-MB) and cardiac troponin-I (cTnI). The total apoptotic cardiomyocytes, B cell lymphoma 2 (Bcl-2) and Bax protein and mRNA expression were detected in the myocardial ischemia (MI) region. The HR and the MAP of the Fen group exceeded that of the I/R group, while the LVDP and ±dp/dtmax were approximate to the basic values. The MDA concentratio...
Tayfun Karatas1*, Betul Apaydın Yıldırım2 and Serkan Yıldırım3
...inotransferase (ALT) and malondialdehyde (MDA) levels, and reduction in superoxide dismutase (SOD), catalase (CAT) activities, glutathione (GSH), total immunoglobulin (T. Ig), and white blood cell (WBC) levels. Moreover, CMN exposure led to degeneration, steatosis, and necrosis in liver hepatocytes as well as hyperemia and inflammation in the liver and caused degeneration, desquamation, necrosis and adhesion in the gill epithelium. Additionally, expression lev...
HAFIZ MUHAMMAD ARSALAN1,2*, SUMMARA TABASSUM1, MUHAMMAD SHERAZ YASIN3, FAROOQ SALEEM4, ZEEMAL SEEMAB AMIN1, MUNIB ASHFAQ1, UMAR FAROOQ GOHAR5 & RASHIDA BASHIR6
