Effect of Inorganic Selenium Supplementation on Thyroid Hormone and Redox Status in Broiler under Dexamethasone Induced Stress
Effect of Inorganic Selenium Supplementation on Thyroid Hormone and Redox Status in Broiler under Dexamethasone Induced Stress
Afshan1, Asad Ullah2*, Imad Khan2, Rafiq Ullah1, Tahira Tayyab1, Fatima Syed3, Raheela Taj3, Shumaila Gul4, Faiza Khan5, Ibad Ullah Jan6, Syed Weqas Ali7 and Assad Ullah8
ABSTRACT
Poultry industries are facing to many challenges which have made it a big problem for humans and birds. One of the major problems is oxidative stress which causes free radical damage and imbalance of thyroid functions. The research experiment was performed to check the effect of orally inorganic selenium on the redox status and thyroid hormones of broilers under dexamethasone induce stress. Day old 100 chicks were purchased from trading hatchery and divided randomly into five different groups having four replicates (n=5) in each group. Broiler chickens feed with starter and finishing commercial corn based basal diet with different concentration of selenium powder. Basal diet (BD) was fed to Group A, which kept as negative control group and no dexamethasone (DE) was offered. Group B was considered as (+ve control group) fed with (BD+15mg DE/kg). The group C, was fed with (BD+0.2mg Se + 15mg DE/kg). Similarly, group D was fed with (BD+0.3mg Se+15mg DE). Group E, fed with (BD+0.4 Se+15mg/kg feed). At the end of the trial, two birds were randomly selected for slaughtering and samples were collected from liver, muscles, kidney and whole blood. The whole blood was centrifuged for further analysis. The redox status and thyroid hormones were measured through commercially available kits. The current study resulted that selenium supplementation improved(P≤0.05) the catalase level in the liver and muscles which fight against the free radical and reduce oxidative stress. In the blood serum the catalase and Malondialdehyde (MDA) both shows significant (P≤0.05). In conclusion I assume that 0.3mg/kg of selenium supplementation in redox status and thyroid hormone show better results in comparison to the control group.
To share on other social networks, click on any share button. What are these?
