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Nisar Ahmad1*, Inayatullah Jan2, Saif Ullah1 and Sidra Pervez1

 

...ution to GDP, employment generation, and export earnings in the economy of Pakistan. Due to modernization in agriculture sector over the last few decades, credit needs of the farmers have increased rapidly. Credit is considered an important factor for raising the productivity and income of the farmers. The current study attempts to analyse the impact of credit on wheat productivity in district Jhang. Furthermore, study explores the purpose of farmers for acqui...

Claudia Kohl*, Andreas Nitsche, Andreas Kurth

Email: kohlc@rki.de

...xt-align: justify;">Next generation sequencing (NGS) opened up a plethora of new research possibilities in biology and medicine. Metagenomics is one of these emerging NGS applications and offers the opportunity to study i.e. whole ecosystems. Basically, the metagenomics approach is similar to well-known shotgun-sequencing, though on a much bigger scale. For instance, the metagenome of a lake would include all the fish, ducks, plants, fungi, bacteria and everyt...

Ummara Waheed Khan, Raza Ahmed, Irum Shahzadi and Mohmmad Maroof Shah

Email | mmshah@ciit.net.pk

...formation and in vitro regeneration offered new dimensions of research to improve important crop species including wheat. The tissue culture by itself has increased the crop improvement potential to develop new cultivars with desirable traits through somaclonal and gametoclonal selection. While successful tissue culture is critical for genetic transformation, it has been facing greater impediments in wheat and related crop species. Its succ...

Tauseef Taj Kiani1*, Mozammil Hussain1 and Hidayat ur Rahman2

 

...re used to develop three generations F2, BC1 and BC2. Heterosis (in F1) and inbreeding depres- sion (in F2, BC1 and BC2) were quanti ed for traits including shelling percentage, kernels per row, kernel rows per ear, and 100-grain weight and grain yield. Non-additive gene action was evident for shelling percentage, kernels per row and 100-grain weight and grain yield for which both het...

Tahir Khan, Raziuddin, Fakharuddin* and Muazam Jamal Razi

...ss of selection in early generations for the improvement of these traits.  

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 Mukhtiar Ahmed, Jana Pickova, Taufiq Ahmad, Muhammad Liaquat, Abid Farid, Muhammad Jahangir

...cular mechanisms such as generation of reactive oxygen precursors and free radicals. Oxidation affects many interactions among food constituents, leading to both desirable and undesirable products. Food lipids are the foods components that are most susceptible to oxidation, therefore oxidation reactions are one of the major sources of deterioration that occurs during manufacturing, storage, distribution and final preparation of foods. Lipid oxidation products ...

Atul Sharma, Aruna Chandra Singh, Gautam Bacher, Sunil Bhand

...n electrochemical signal generation. Aptamers possesses the strong potential as receptors for the development of biosensors for antibiotics detection; therefore, a specially designed aptamer specific to an antibiotic may be suitable for this purpose. In this review, the importance of detection of antibiotic residue contamination, reported analytical methods, advancement in biosensing platform especially regarding electrochemical transduction are discussed in d...

Faiqah Ramzan*1 and Muhammad Haris Ramzan2

...ns. As, dose dependent degeneration of prostate gland has been described following intraperitoneal kisspeptin treatment. However, effects of kisspeptin administration on the levels of prostatic citric acid remain elusive till date. The present study, therefore, addresses the effects of 12 day administration of kisspeptin on prostatic citric acid levels in male mice. Kisspeptin-10 was administered intraperitoneally in different dosage concentrations (1μg, 1 ...

Muhammad Saeed* and Iftikhar Hussain Khalil

...ants recovered in latter generations.

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 Ali Zurwan1,*, Muhammad Moaeen-ud-Din2, Ghulam Bilal2, Zia-ur-Rehman1,2 and Muhammad Sajjad Khan1

...ded pedigree for several generations however, this is really useful firsthand information.
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Muhammad Noor, Hidayat ur Rahman and Muhammad Iqbal

...ross-III. The mean of F1 generations was low in almost all crosses from their parents for flowering and plant characters. It is concluded that in all crosses broad and narrow sense heritability estimates were of moderate to high range, indicating that the total variability was mostly of genetic nature and hence, could be effectively utilized in maize breeding programs for developing popcorn varieties having early maturity and accompanied with other desirable a...

Nilesh Suresh Gole and Bijan Kumar Das

Biology of Dichromia sagitta (Fabricius) (Noctuidae: Lepidoptera), a serious pest of Indian ipecac, Tylophora indica
...were several overlapping generations in a year. Descriptions of different life stages have been made. Adaptive behaviour of D. sagitta and its interaction with toxic host plant have been discussed critically.


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1Sitesh Chatterjee, 1Chirasree Gangopadhyay and 2Santosh Kumar Roy
...ield bio-efficacy of new generation molecules against rice insect-pests. Control of pests in seedbed is relatively less expensive than transplanted main-field because of smaller area of nursery that can be managed better way as compared to transplanted field. In the present study, chlorantraniliprole granule was applied both in seedbed and transplanted field along with spraying of some new generation insecticides like indoxa...

Qudsia Khalid, Safdar Hussain Shah*, Faiza Zaeem and Saad Hussain Shah 

...netin (0.25 mg/l). For regeneration MS medium with 1.0mg/l NAA and BAP + 30g/l D-Sorbitol was used. LiCl adapted line showed significantly higher indices of tolerance than unadapted line at 100, 150, 200 and 250 mM NaCl stress. Adaptation resulted in enhanced accumulation of saturated fatty acids (myristic and stearic acids), while unsaturated fatty acids exhibited variable profiles with enhanced oleic acid and significantly reduced linoleic acid. The re

Zaheer Abbas*, Shaukat Ali, Jalal-Ud-Din and Ghulam M. Ali* 

...cient and reproducible regeneration system from coleoptilar node of elite maize inbred line was developed. Regeneration from coleoptilar node circumvented tedious procedures of raising the immature embryos as a starting material for genetic transformation. Unlike immature embryos, the development of coleoptilar node is seasonal free and green house independent which would accelerate the work relevant to genetic transformatio...
Liana Mihaela Fericean1* and Mihaela Corneanu2
...henogenetically to three generations of fundatrigenous. In July, the winged form migrated to the secondary host, where successive generations have been born through parthenogenetic reproduction. Gynopara in October return to the primary host and give birth to wingless oviparae that mate with males and lay winter eggs. The biometrical measurements of Aphis nasturtii help to complete knowledge on external morphology of ...
Muhsan Ali Kalhoro1,2, Danling Tang1,*, Ye Hai Jun1, Morozov Evgeny1, Sufen Wang1 and Muhammad Aslam Buzdar
...istani waters for future generation.
...

Soraya Khosravian Dehordi*, Abdolnaser Mohebbi and Kahin Shahanipour

...mful health effects. The generation of oxidative stress creates by the common mechanism their carcinogenicity and toxicity. The present study was planned to determine whether an oral administration of nano-selenium (nano-Se) influencing on biomarkers of oxidative status in the rats spleen exposed to the cadmium (Cd) metal. For this purpose, thirty male rats equally divided into six groups, group I received nano-Se (0.1mg/kg) alone as dose, group II selenite od...

 Mohammed Mahbub Iqbal*, Mehedi Hasan Kanon, Mohammad Amzad Hossain, Abul Hossain, Shamima Nasren, Md. Jahidul Islam, Md. Arifur Rahman

...ep for the use of future generation.

...

Zahid Akram, Saif Ullah Ajmal, Ghulam Shabbir, Muhammad Munir and Nasir Mahmood Cheema

INHERITANCE MECHANISM OF SOME YIELD COMPONENTS IN BREAD WHEAT
...or these traits in early generation may not be useful and it has to be delayed till segregating generations.
...

 Z. A. Soomro, M.B. Kumbhar, A.S. Larik*, M. Imran** and S.A. Brohi***

...y heritable in F2 and F3 generations except sympodia/plant, indicating quantitative pattern of inheritance, offering better chances of selection for these traits in F2 and F3 generations. The traits namely plant height, bolls/plant and seed cotton yield/plant displayed high heritability (72.97 - 75.55%) with remarkable genetic advance (112.46 - 357.01%) indicating that these traits were predominantly governed by additive gen...

 Abid Hussain*, Imdad Hussain Mirza and Muhammad Azeem Khan**

...and thrive for countless generations. Proper feeding and management is of fundamental importance to the success of any goats’ enterprise. In Pothowar region of Punjab, household and sedentary system of goat production is practiced. The availability of feed varies according to the season. Goats in the region are under nourished and producing less than potential. This study was conducted to find out the feed supplementation practices of goats in the Pothow...

 Sarfraz Ahmad, Shaista Koukab, Nayyar Razzaq, Muhammad Islam, Aneel Rose*, and Muhammad Aslam**

...ecutita has also shown regeneration potential on marginal lands. Commercial scale production of M. recutita is possible in highlands of Balochistan. However, further studies are required to evaluate different genotypes/varieties, essential oil contents at various growth stages, oil extraction techniques, mechanized flower picking, drying/storage techniques and cultivation practices in the existing cropping patterns.

...
Qin Liu1,2, Feiwei Liu1, Xiuyue Zhang1, Nan Yang1 and Jianghong Ran1,*
...chenyii using a next-generation sequencing technology. The allele number of these loci ranged from two to six in genotyped 35 individuals. Polymorphism information content ranged from 0.2735 to 0.7717 with an average of 0.5149. Observed and expected heterozygosities at each locus ranged from 0 to 0.879 and 0.332 to 0.814, respectively. These markers could be used to better understand the breeding system and protection manage of this species.
...

 Muhammad Arifullah, Muhammad Munir*, Abid Mahmood**, Saifullah Khan Ajmal and Ghulam Shabbir*

COMBINING ABILITY ANALYSIS OF SOME YIELD ATTRIBUTES IN INDIAN MUSTARD (BRASSICA JUNCEA L.)
... up to sixth segregating generation for number of primary branches, number of siliqua per plant, siliqua length and seed yield due to highly significant genotypic mean square and pre-dominant role of nonadditive type of gene action while for number of seeds per siliqua and seed weight, selection in early generations would be suitable due to prominance of additive gene action.

...

 Sadia Tehrim*, M. Yasin Mirza** and G. Mustafa Sajid*

COMPARATIVE STUDY OF DIFFERENT GROWTH REGULATORS FOR EFFICIENT PLANT REGENERATION IN GRAPES
...rmonal combinations in regeneration media were studied to determine the best combination for in vitro morphogenesis of grapevine accessions viz., 4494(1) Kowar Sufaid, 4472(12) Harker Agoon and 4492(1) Kowar Naray. When levels of benzylaminopurine (BAP) were increased in the basal MS media for culturing the grape plantlets, there was a corresponding increase in the number of shoots and root mass. Additionally, the shoot proliferation response to increasing lev...

 Mazher Abbas*, Irfan Mehmood*, Arshed Bashir*, Muhammad Ather Mehmood* and Sonila Hassan* 

WOMEN COTTON PICKERS PERCEPTIONS ABOUT HEALTH HAZARDS DUE TO PESTICIDE USE IN IRRIGATED PUNJAB
...ve of largest employment generation both for males and females in the production and value chains. Cotton picking is primarily a female specific activity in all cropping zones of Pakistan. Women cotton pickers mostly belong to poor rural society involved in this labour force to feed their families. Cotton pickers in Pakistan face some serious health related problems due to heavy use of pesticides on cotton crop. The present study was designed to investigate th...

 Syed Asif Imran Shah*, Shah Jehan Khan**, Abdul Aziz Baloch*** ,
Obaid Ullah Sayal**, Kalim Ullah* andShujaat Ali**

COMBINING ABILITY ANALYSIS IN VARIOUS INBRED LINES OF MAIZE (ZEA MAYS L.)
...ield. Selection in early generation will be more effective in Islamabad White whereas Islamabad Gold in later generation due to dominant and additive genetic background, respectively.

...

 Junaid Alvi*, Ijaz Ashraf*, Khalid Mehmood Ch*, Muhammad Iftikhar* and Saleem Ashraf**

IMPACT OF LIVESTOCK IN UPLIFTING RURAL LIVELIHOOD
...idely adopted for income generation. More than 22% respondents earned a maximum income of more than Rs.15000. Livestock have dominant effect on domestic needs fulfillment. Farmers were spending income on family chores, education, health and other aspects of life. Informal discussions and observation dictated the lower productivity than the potential and inadequate awareness and adoption of precise dairy farming practices. Livestock keepers demanded provision o...

 Nasarullah*, Raiz uddin*, Fakhar Uddin* and Muhammad Jamal*

INTERPRETING WHEAT GENOTYPES FOR GRAIN YIELD UNDER DIFFERENT REGIMES OF KHYBER PAKHTUNKHWA
...ss of selection in early generation for the improvement of these traits. Genotypes Faisalabad-2008 and line from Tajikistan (2S-3094) performed better for most of yield and associated traits across both environments therefore could be an asset for plant breeders to breed genotypes suitable for diverse environments.

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 Nazia Qamar1, Sher Khan Panhwar1,* and Ralf Riedel2,*
...n for current and future generations.
...

Muhammad Ismaeel1,2*, Syed Mehar Ali Shah1, Aziz Ur Rahman1 and Mian Ahmad Raza

...ended to develop advance generations and improved rice varieties 

...

Xiangbin Meng1,Tianxiang Gao2, Chunhou Li3, Na Song1, Lu Liu1, Liqin Liu2 and Xiumei Zhang1,*

 

...ecies. We performed next-generation sequencing and de novo assembly to obtain potential useful microsatellite markers for S. esculenta. Among 80 tested microsatellite markers, 19 showed polymorphism among S. esculenta individuals. The allele number of all polymorphic microsatellite markers ranged from 6 to 10. Expected and observed heterozygosity varied from 0.260 to 0.904 and from 0.292 to 0.861, with an average of 0.741 and 0.607, respec...
Rida Zainab1, Sana Elahi1, Afshan Kaleem2,*, Daniel C. Hoessli3, Mehwish Iqtedar2, Roheena Abdullah2, Faiza Saleem2, Shanza Khan1, Anusha Ijaz1, Shagufta Naz2 and Abdul R. Shakoori4,5,*
...tual disturbances. First generation antipsychotics for Schizophrenia were replaced with by second generation ones with less side-effects like Parkinsonism and Hyperprolactinemia. A novel, computer-based drug designing technique, has emerged to develop more efficient drugs. One of the computational methods becoming increasingly popular to develop new drugs is relying on Pharmacophores. This method was utilized to develop phar...
Li Lv1, Liuan Li1,*, Ruibo Zhang1, Zhichao Deng1, Tianming Jin1 and Gaimei Du2
...g selenium using hydride generation-atomic fluorescence spectrometry. Selenium dietary supplementation significantly increased egg white, egg yolk and total egg levels, as well as daily egg production (P < 0.05). During the study, egg white, egg yolk and total egg selenium, as well as egg production, initially increased for low- and medium-dose groups and then plateaued. In contrast, these parameters initially increased and subsequently decreased for...
Şehriban Çek Yalnız 1,* and Erdal Yilmaz2
...ge, surface blebbing and generation of apoptotic bodies by cell fragmentation were evidence of apoptosis. In pre and postovulatory follicles, karyorhexis and the budding phenomena were clearly detected. Karyorhexis and budding phenomena were also the sing of apoptosis. Atresia was also clearly detected in pre and postovulatory follicles. The detection of karyorhexis, characteristic of apoptotic cells may provide a better understanding in atresia mechanism. It ...

Monsif Ur Rehman1*, Hidayat-ur-Rahman1, Muhammad Iqbal2, Iftikhar Hussain Khalil1 and Zahir Shah3 

 Tahir Abbas*1, Khawaja Raees Ahmad2, Asmatullah3, Khalid Pervaiz Lone4, Muhammad Ali Kanwal2, Sadia Suleman2

Reno-hepatic protective effects of Jambul against chromium induced anomalies in mice
...ver rehabilitation and regeneration. The JFE significantly recovered the histopathological alterations in reno-hepatic tissue by free radicals scavenging and metal chelating abilities due to presence of anthocyanin, flavonoids and β-sitosterol. The JFE’sprotective effects against heavy metals environmental toxicants especially Cr+6 is novel and cheapest; that should be sponsored for ethno-medicinal purpose.

...

 Raazia Kiran1, Alya Riaz1, Muhammad Irfan1*, Hafiz Abdullah Shakir2

An overview of pre-treatment methods used for bioconversion of lignocellulosic biomasses into valuable products
... /> environment. Second generation (2G) or cellulosic bio-ethanol is produced from the
biomass in three main steps that are pre-treatment, hydrolysis, and fermentation.
The pre-treatment method involves the use of different physical processes i.e., size
reduction, steaming or boiling, ultrasonication, and bursting, chemical methods i.e.,
solvents, acids, salts, bases, the physicochemical processes include liquid hot
water an...

Muhammad Shahzad Khattak1*, Amjad Khan1, Mahmood Alam Khan1, Waqas Ahmad2, Shafiq ur Rehman3, Mohammad Sharif4 and Sajjad Ahmad1 

...roduction and hydropower generation. In this research, the characteristics of hydrological droughts in Indus River basin using stream flow data of major rivers of Pakistan were investigated. Stream flow drought indices (SDI) were used to determine the severity of droughts for the Indus, Jhelum, Chenab and Kabul River at Tarbela, Mangla, Marala and Warsak hydrological stations for the period 1962-2011. A drought spell starting from 1999 and ending in 2002 was o...

Mubashir Ahmad Khan*, Nazakat Nawaz, Muhammad Arshad, Muhammad Ayub Khan, Tahira, Doulat Baig, Ihsan Ullah Khan and Shamim ul Sibtain Shah 

...elections in segregating generations. This will help to increase sesame crop yield in the country. 

...

Ali Awais, Charassri Nualsri and Watcharin Soonsuwon* 

..., the EMS response in M1 generation was also observed in the field condition by various quantitative measurements. The traits, especially plant height, panicle length, number of filled grains, number of grains per panicle, 1000 grain weight and yield per plant showed a clear fall off when compared to control while the panicle length in both mutants were higher than that of control. Several mutants also revealed some notable phenotypic variations in the roots, ...

Rizwan Ullah Shah* and Iqbal Munir 

...owed by shoot and root regeneration of Brassica carinata. Seeds were sterilized and germinated, of which one week cotyledon and hypocotyl were used for callus formation and shoot regeneration at five different level of 1-naphthaleneacetic acid NAA (0.05, 0.1, 0.5, 1.0 and 1.5 mg/l) and 6-benzyl amino purine BAP (0.1, 0.5, 0.7, 1.0 and 1.5 mg/l), and root regeneration at four levels of indo...
Liqin Liu, Maoting Wang, Zhenming Lü, Li Gong*, ChangWen Wu, Baoying Guo and Lihua Jiang
...araonis through next-generation sequencing technology. A total of 100 alleles were detected, and the number of alleles per loci ranged from 2 to 9. The observed and expected heterozygosities per loci ranged from 0.000 to 0.531 and from 0.031 to 0.751, respectively. Polymorphism information content (PIC) showed that six loci were highly informative (PIC > 0.5). Five loci (CL1142, CL1770, CL2683, CL3494, CL 3674) significantly deviated from the Hardy-Wein...
Khalid Khan1, Saima Liaqat2*, Somaiya Rasheed1 and Ihsanullah Kakar3
...sed livestock for income generation. Furthermore, livestock have a predominant role to accomplish the rudimentary needs of the households. Moreover, livestock offer opportunities of income generation and to spend it on education, health and housing, which eventually enhanced the living standard of the households. However, orthodox and dogmatic methods, inadequate awareness and lack of animals’ hospitals lead to hamper ...
Muhammad Hidayat Rasool1,*, Muhammad Zaheer1, Muhammad Farooque Hassan2, Muhammad Shafique1 and Muhammad Usman Qamar1
...and 4th generation cephalosporin and carbapenems is an issue of high importance. Present study was aimed to determine the frequency and antimicrobial susceptibility patterns of MBL producing carbapenem-resistant Gram-negative rods (GNRs) isolated from clinical specimens. A clinical descriptive study was conducted in Faisalabad, Pakistan from June 2016 to January 2017. A total of 152 clinical samples were processed according to standard microbi...

 Abdul Khaliq1, Muhammad Irfan Ullah1,*, Muhammad Afzal1, Akhlaq Ahmad2 and Yasir Iftikhar3

...llowing by F1 generation. Phosphine fitness in term of mortality mean calculated at 300 ppm was minimum against weevil but highly effective against red flour beetle after 24hours while, at 400ppm showed same resistance level in all. At 500ppm, lesser grain borer (LGB) was more susceptible as compared to others as in rice weevil. Nicotiana tabacum (L.) and Calotropis procera (Aiton) oil both at 15% were most lethal to LGB, weevil and re...
Guo-hai Wang1, Zai-xi Yang1, Pan Chen1, Wei-ning Tan2 and Chang-hu Lu1,*
...ed dispersal and plant regeneration in particular habitats by frugivorous birds are of great concern. In this study, we recorded the bird’s seed foraging and dispersing behavior of local bird species to examine their role in dispersing seeds of Kmeria septentrionalis, an endangered tree species in a karst habitat in southwest China. Twenty-seven bird species were recorded feeding on its seeds, and fourteen bird species were confirmed as seeds disp...

 Tazeen Jamil, Saba Ijaz, Rabia Arif*, Faiza Akram and Muhammad Saleem

...ents in four consecutive generations of different strains of Sordaria fimicola. The parental strains werecollected from two contrasting environments of Evolution Canyon i.e. harsh South facing slope and neutral North facing slope. Retroelements profiles were generated in order to detect retrotransposons. Strains from South facing slope exhibited more copy number of Ty3-gypsy, LINEs and Ty1-copia as compared to strains from North facing slo...
Fakhra Soomro1,*, Riffat Sultana2 and Muhammad Saeed Wagan2
...e and usually giving two generation in a year but occasionally third generation of diapauses eggs of S. savignyi hatched in winter. A comparative key for immature stages of both species was constructed. Almost all immature stages occupied similar habitats as that of adults and their appropriate stages were differentiated through combination of characters i.e. coloration, morphometry, pronotum, femur bands, wing...

Abid Ali1*, Hidayat ur Rahman1, Farhatullah1 and Zahir Shah

...ackcrosses BC11 and BC12 generations during spring 2016. The total experimental material in this study consisted of three parental inbred lines, six F1s, six F2s, six BC11, six BC12 and check cultivar P30K08 which were evaluated at two locations i.e. CCRI, Pirsabak, Nowshera and The University of Agriculture (UAP), Peshawar-Pakistan in a RCB design having three replications during kharif, 2016. Generation means analysis (GMA...
Pin Lyu1, Xiangxian Chen2* andQinlong Liu3*
...ssion, skeletal muscle regeneration, control of skeletal muscle fibrosis and muscular tissue re-construction. The skeletal muscular structure and C-reactive protein level could reflect the recovery process after skeletal muscles injury with high sensitivity in groups with the four different rehabilitation methods. 
...
Saeed Murtaza1,*, Nazir Ahmad2, Muhammad Asif Raza3, Muhammad Saleem Akhtar1, Muhammad Mazhar Ayaz4, Muhammad Ali5 and Rais Ahmed6
...epididymis, testicular degeneration with or without mineralization, testicular abscesses and chronic epididymitis. In early stages, sperm granuloma appeared as an anechoic mass with ill-defined border. In advanced stages, it exhibited a mixture of anechoic and hyperechoic areas, encircled by a thick hyperechoic border. In early cases of testicular degeneration, testicular parenchyma showed reduced echogenicity. However, in a...

Muhammad Noman, Yong Tong Mu*, Muhammad Mohsin, Aamir Mahmood Memon and Muhammad Talib Kalhoro

...hery resource for future generations.
...
Abdul Waheed1,2, Sidrah Saleem1, Naveed Shahzad3, Junaid Akhtar4, Muhammad Saeed5, Iqra Jameel1, Farhan Rasheed6 and Shah Jahan7,*
... resistant against third generation cephalosporin and Aztreonam. Notably, 15% of ESBL producing strains harbored blaSHV gene while 43% were positive for blaOXA gene. In a nutshell, diverse variety of ESBL-positive GNRs is distributed, the findings of the present study should be considered for planning strategies to treat and prevent the further spread of ESBL-producing gram-negative rods infections.
...
Yacheng Hu1,2, Xueqing Liu1,2, Jing Yang1,2, Kan Xiao1,2, Binzhong Wang1,2 and Hejun Du1,2,*
...squo;s sturgeon via next-generation sequencing from Chinese sturgeon (Acipenser sinensis). The 17 microsatellites were polymorphic with 3 to 6 alleles per locus and the total number of alleles is 80. The mean expected heterozygosity (HE, 0.506 to 0.781), observed heterozygosity (HO, 0.542 to 1), Hardy-Weinberg departure value (d, -0.042 to 0.427), polymorphic information content (PIC, 0.482 to 0.753) and...
Aqsa Pervaiz1*, Rukhshanda Afridi1, Zahra Pervaiz1, Rabia Masood1 and Hira Pervaiz2
...observed in liver were degeneration of hemopoietic tissue, destruction of hepatocytes, degeneration of bile duct, inflammatory infiltration, vacuolization, pyknosis, presence of MMCs and necrosis in hepatocytes. It can be concludedthat methylmercury has harmful effects on histology of liver of fish. Therefore, the present work suggests that the exposure to the methylmercury should be prevented to avoid injurious health hazar...
Jiaxin Guo1, Xiumei Zhang1,2, Xiaoyan Wang2, Liqin Liu2 and Tianxiang Gao1,*
... In this study, next-generation sequencing and de novo assembly were used for potential useful microsatellite markers obtaining of S. japonica. A total of 120 microsatellite markers were designed and tested, 25 primer pairs showed polymorphism among S. japonica individuals. Number of alleles, observed and expected heterozygosity per locus ranged from 2 to 8, 0.083 to 0.922 and 0.042 to 0.866, respectively. The PIC ranged from 0.04 to 0...

Muhammad Khuram Razzaq1,2*, Saeed Rauf1, Mohsin Khurshid3, Shahid Iqbal1,4, Javaid Akhter Bhat2, Ayaz Farzand5, Adeel Riaz1,6, Guangnan Xing2 and Junyi Gai

 

...ility in the segregating generation warrants good selection response. Moreover, magnitude and type of genetic variation associated with pollen viability also important in improving the trait and breeding procedures to be adapted for the improvement of trait per se. Genetic studies results under heat stress in sunflower showed additive to partial dominance towards higher pollen viability in the inheritance showing that trait can be improved through selection in...

Hala Rajab1, Muhammad Sayyar Khan1*, Safdar Hussain Shah1 and Syed Mehar Ali Shah2 

...thod led to successful regeneration of shoots on Murashige and Skoog (MS) media containing BAP 3 mgL-1 and developed roots in ½ MS media supplemented with IBA 3 mgL-1 in case of OSCAR cultivar. Successful selection of transgenic lines was achieved using selective antibiotic kanamycin 50 mgL-1. NtSAT4 gene integration into the plants genome was confirmed by PCR using the NtSAT4 gene specific primers. The positive transgenic lines were successfully accli...

Umar Hayat1*, Shahid Ali1, Abdul Mateen2 and Hazrat Bilal

...these sectors for income generation activities which will provide a solution to the key economic issues in the country to meet the sustainable development targets of United Nations 

...
Chaman Ara1*, Asmatullah1, Sehrish Kanwa1, Asma Chaudhary2, Ayesha Siddiqua1
...lone antibiotic of third generation, is widely used to treat respiratory and genitourinary infections. Keeping in view the controversy about its toxicity, current study was conducted to assess the levofloxacin induced hepatotoxicity, nephrotoxicity and its likely noxious effects on spermatogenesis in mammals. Forty mice, randomly categorized into four groups (N=10) were administered orally with different concentrations of levofloxacin (0.00, 9.37, 18.75 and 37...
Peng Chen1,2, Zuhao Huang3,Chaoying Zhu1, Yuqing Han1, Zhifeng Xu1
Guanglong Sun1, Zhen Zhang1, Dongqin Zhao4, Gang Ge1 and Luzhang Ruan1*
... study, we used the next-generation sequencing method to obtain mitochondrial DNA (mtDNA) of Porzana paykullii, Rallus aquaticus and Gallirallus striatus in Gruiformes, and Hydrophasianus chirurgus in Charadriiformes, after which we analysed and compared structure, phylogeny, and taxonomic origin of the Gruiformes and Charadriiformes. Based on sequencing, splicing, and annotating the mtDNA of four birds, the results showed that the ...
Sajida Rasool1, Saba Irshad1*, Neelam Saba1, Mehak Fiaz1Muhammad Sajid Hussain2, MuhammadWajid Hussain3 and Peter Nürnberg2

 

...and upper motor neuron degeneration. BICD2 is an adaptor protein which regulates the cellular trafficking of cargo molecules crucial for motor neuron growth and maturation. In present study, a Pakistani family of HSP penetrating in autosomal recessive pattern was ascertained. Patients presented spasticity and stiffness of upper and lower limbs, severe microcephaly, dysphagia, no speech, hearing loss and seizures. Genome wide linkage analysis and whole exome se...
Nurlybay Kazhgaliyev1*, Talgat Kulmagambetov2, Dulat Ibrayev1, Saule Bostanova1 and Zhanat Titanov1
...rd heifers of the second generation at the age 18-22 months was 378.5 and 375.2 kg which was 8.7 and 20.6 kg (2.2-5.4%) higher than that of Aberdeen-Angus herd-mates. Chemical analysis of feedstuff was carried out in Altyndan LLP and AKA whereas physiological and clinical indicators of second-generation heifer calves were within the normal range in various seasons. The highest thermal resistance index was in animals of group...

Bamigboye Olutoyin Omolara1, Fapohunda Funmilayo Omotoyosi1, Oladipo Elijah Kolawole1,2, Oni Mattthew Olujenyo1, Ajibade Oluwatosin Akinola1, Kaka Mary Oluwatosin1* 

...BcAb while using a third generation ELISA kit for screening. The mean CD4+ count and age were 479.12 ± 23.48 cells/µl and 48.56 ± 1.27 years, respectively. Only six samples out of ninety-three HIV-positive samples were positive to HBsAg while fifty-four samples (58.1%) were positive for HBcAb however, HBeAg marker was negative among all samples. Interestingly, the prevalence of the HBV infection was more in females (66.6%) compared to the m...
Bhandari Jyoti1,2, Yasen Shali3, Zhang Zehua4, Yao Xiaoho5, Deng Jiang3, Zhang Yaling5, Wang Cuiling5, Li Yang5, Lei Xueping5, Wang Wenfeng5, Mohammad Farooque Hassan6 and Li Can1,*
...enerating two incomplete generations a year in meadow and one generation a year in farmland. The Iwao’s M*-m regression analysis, Taylor’s power law and aggregation cause analysis showed an aggregated distribution pattern for L. m. tibetensis Chen. It is concluded that insect behavior and environmental conditions co-influence the population density and spatial distribution pattern of this pest.
...
Nafeesa Batool1*, Javed Iqbal Qazi1, Nida Aziz1, Ali Hussain2 and Syed Zawwar Hussain Shah3
...Co-AD upturns the biogas generation efficiency. Thus, we can conclude that BMP assays are extremely useful to determine the amount of bio-methane and bio-degradability of the organic substrates and would facilitate in the preliminary selection systems for the field scale applications especially in framework of developing countries.
...

Muhammad Ilyas1, Sardar Ali Khan1, Shahid Iqbal Awan1, Shafiq-ur-Rehman1, Waqar Ahmed1, Muhammad Riaz Khan2, Raja Mohib Muazzam Naz2, Muhammad Mohib Ullah Khan3 and Sumaira Hafeez1* 

...ls in basic experimental generations. Initially, 108 inbred lines of maize were planted in two separate trails under water deficit and normal irrigation conditions in the experimental field of Department of Plant Breeding and Molecular Genetics. Selection of parents for further study was done with regards to grain yield and its component traits. Broad range of genetic diversity was shown by the inbred lines and displayed different levels of drought tolerance. ...

Muhammad Ilyas1*, Sardar Ali Khan1, Shahid Iqbal Awan1, Shafiq-ur-Rehman1, Muhammad Riaz Khan2 and Sumaira Hafeez1 

...lected inbred lines. Six generations as P1, P2, F1, F2, BC1 and BC2 were prepared for both the crosses to calculate heterosis and inbreeding depression for Randomized Complete Block Design under split plot arrangement. Highly significant inbreeding depression was recorded for all traits indicating a dominant type of gene action. Heterosis was high for both crosses along with high inbreeding depression. All these results exhibit that the hybrid breeding is the ...

Fazli Ahad1, Raziuddin1, Nazir Ahmad1,2*, Muhammad Nauman1, Touheed Iqbal3, Nabeel Khan1, Fazli Hameed4 and Quaid Hussain2 

...e effective in the early generation for the improvement of these traits. Correlation analysis indicated that flowering (rp=0.45), primary branches plant-1 (rp=0.49), main raceme length (rp=0.41), seeds pod-1 (rp=0.41) and 1000-seed weight (rp=0.38) had positive and significant association with seed yield plant-1. Genotypes, DH4, DH5, DH8, CA5 × DH6, CA5 × DH7, CA5 × DH3, and CA2 × DH7 displayed well genetic potential for the majority of...

Filza Fatima Rizvi1, Muhammad Umair1, Muhammad Kahlid Jamil2*, Masooma Hassan2, Komal Qayyum1 and Syed Mohsin Raza Kazmi

...nt, living standards and generation of wealth of any country. Globally, energy generation scenario is shifting towards renewable sources and its application in different sectors for example Agriculture. Oil, gas and coal. The same is true for Pakistan that has agriculture based economy. The present study was undertaken to review energy consumption in the agriculture sector of Pothohar region of Pakistan. This region has no p...

K. Osei1† , A. I. Adama1 , E. C. Tagoe2 and J. Sackey-Asante1

 

Biochar effect on nematodes and insects population density, soil improvement and yield of okra
... significance and income generation potential. Agricultural production worldwide is constrained by abiotic and biotic factors. Chemical fertilizers are usually used to solve soil infertility problems. However, chemical fertilizers are expensive and when applied continuously, degrade agricultural lands (Savci, 2012; Bhattacharyya et al., 2015). Biotic factors such as plant parasitic nematodes (PPN) and foliar insects have been implicated as major constraints to...

Farid Ullah Khan*, Adeel Ahmed*, Uzair Khan Jadoon*, Fahim Haider* 

MODELING, SIMULATION AND FABRICATION OF AN UNDERSHOT FLOATING WATERWHEEL
...ing waterwheel for power generation
for run-of-the-river applications. For the undershot floating waterwheel, analytical modeling and simulation are performed
to estimate the optimal design parameters. Moreover, the dependence of output power on various parameters
of waterwheel is also investigated during simulations. It is found, during analysis that the water flow velocity is the
major factor affecting the output power and due to ...

Numan Habib, Naseer Ahmed, Riaz Muhammad, Himayat Ullah, Muftooh Ur Rehman, Kareem Akhtar 

ANALYSIS OF CHIP PRODUCED IN FREE MACHINING OF TI-6AL-7ZR-3NB-4MO-0.9ND AND TI-5AL-7ZR-7NB-0.7ND ALLOYS
... like aviation and power generation increased its use in many applications, not only because of its chemical properties but also because of its excellent properties including, high strength to density ratio, withstand with high stresses, better fatigue and corrosion properties and ability to resist high temperatures. However, all these properties of this alloy results in poor machinability, hence, make the automatic machining of these alloys nearly difficult...

 Numan Habib1, Naseer Ahmed1, Riaz Muhammad1*, Himayat Ullah2, Muftooh Ur Rehman1, Kareem Akhtar3

ANALYSIS OF CHIP PRODUCED IN FREE MACHINING OF TI-6AL-7ZR-3NB- 4MO-0.9ND AND TI-5AL-7ZR-7NB-0.7ND ALLOYS
... like aviation and power generation increased its use in many applications, not only because of its chemical
properties but also because of its excellent properties including, high strength to density ratio, withstand with high
stresses, better fatigue and corrosion properties and ability to resist high temperatures. However, all these properties
of this alloy results in poor machinability, hence, make the automatic machinin...

 Nashitah Alwaz1, Safdar Raza1*, Sadaqat Ali1

A COMMUNICATION-FREE SIGNAL GENERATING TECHNIQUE FOR REACTIVE POWER CORRECTION IN ISLANDED MICROGRID
...ng different distributed generation (DG) units according to the load demands. The droop control methods are normally used for appropriate power sharing. However, these control techniques suffer badly due to the feeder impedances and uncontrollable power coupling issues. Many techniques have been proposed to share power accurately, most of them rely on communication
link. In this work a localized/communica...

Adnan Tariq,1 Iftikhar Hussain,2 Abdul Ghafoor,3 Sahar Noor2

AN EVOLUTIONARY ALGORITHM FOR JOB-SHOP SCHEDULING
...for the problem in fewer generations.
...

Rashidullah*, Irshad Ahmad**

SEISMIC HAZARD ANALYSIS OF ISLAMABAD
...e and Atkinson 2008 next generation attenuation (BA08 NGA) has been used for the determination of the ground motion parameters. Maximum PGA of 0.49g by BA08 NGA obtained for Islamabad at rock site due to Main Boundary Thrust (MBT). In PSHA using the Crisis-2007 software, PGA values with 10% probability of exceedance in 50 years i.e. the return period of 475 years have been determined. The PGA results obtained at bedrock are 0.28g by BA08 NG...

 Muhammad Waseem*, Irshad Ahmad**, Muhammad Asif Khan**

DETERMINISTIC SEISMIC HAZARD ANALYSIS AND SELECTION OF TIME HISTORIES FOR DYNAMIC ANALYSIS FOR A SITE IN SWABI

Hina Imtiaz1*, Salma Khalid2, Kashaf Riaz1, Muhammad Arshad Ullah3 and Zubair Rehman

...rding the types of waste generation, diseases among the residents and their opinions about the recycling and proper waste management were carried out through self-administered questionnaires. In order to observe coagulant effect according to Pakistan National Environmental Quality (Standards (Pak-NEQS), the collected samples were treated in the laboratory for identification and recommending suitable coagulant. Three different treatments were practiced i.e. Alu...

Ghulam Akbar1*, Ali Ahmad2, Neha Arooj1, Muhammad Anjum Zia1, Aamna Rafique1, Sania Riasat1, Mohsin Raza1, Mahpara Qamar1, Shahneela Nusrat1 and Shakila Hanif1

Critical Update for the Treatment of Anemia by using Advanced Genome Editing Crispr Cas Technology
... with the development in generation at genome editing level have made feasible to accurate mutations in human genome. A site oriented specific break in double stranded DNA is induced by CRISPR/Cas9, whereas different oligonucleotides are provided to make accurate DNA template for genome correction. It is of importance to knowledge about types of CRISPR to treat anemia. Cas 9 showed one of best gene editing reactions than others. Recent data gives authentic app...
Muhammad Umer Khan1,2*, Muhammad Farooq Sabar1, Atif Amin Baig3, Arif-un-Nisa Naqvi4 and Muhammad Usman Ghani1
...ing dataset for curative generation of future mtDNA databases in Pakistan.
...
Zulekha Zameer, Samreen Mohsin, Ammarah Hasnain, Asma Maqbool* and Kauser Abdulla Malik
Influence of Explant Sources on in vitro Callogenesis and Regeneration in Maize (Zea mays L.)
...ghout the year and low regeneration response. The present study is aimed to investigate the effect of various explants sources for callogenesis and regeneration in maize (Pioner 3025). The main explants under consideration were: three parts of germinated seedlings, mature embryo and split seeds. Each of these explants was evaluated for its ability to form callus and to regenerate subsequently. For callogenesis from different...

Turgay Şişman1,*, Muhammet Çağrı Keskin1, Hatice Dane1, Şeymanur Adil1, Fatime Geyikoğlu1, Suat Çolak2 and Esra Canpolat1

...rallel with hepatocyte degeneration and heterogenic vascular construction originating from congestion, deformation and dilatation. In kidney, degeneration, congestion, dilatation, and necrosis in proximal and distal tubules were recorded; moreover, expansions of Bowman’s space, infiltrations of lymphocytes, and glomerulonephritis were observed. Also, the frequency of nuclear abnormalities in erythrocytes showed signifi...
Yonghua Liu*, Xianhua Li, Xiongfei Yan and Gang Li
...867, respectively). Mean generation time was the longest on apple (58.41 d) and peach (58.45 d). Population doubling time was shortest on apricot (7.77 d) and plum (8.33 d). Of the 4 hosts, apricot and peach are more suitable for A. fimbriana growth, development, and reproduction. The results of this study provide an important basis for forecasting and integrated management of A. fimbriana.
...
Abdul Hameed1*, Ihtsham ul Haq Padda2 and Abdul Salam3
Estimating Food Consumption Patterns in Pakistan by Using Ideal Demand System
...centrate on rural income generation activities such as agriculture, livestock and its related industries.

...
Aamer Sharif1,*, Muftooh Ur Rehman Siddiqi1 and Riaz Muhammad2
...ndly, reliable and clean generation of electricity. Gravitational water vortex power plant is certainly one of such low head hydro turbines in which the potential energy of free surface flowing water is converted into kinetic energy through vortex turbine that tangentially passing the water into the basin, which forms a powerful water vortex. This study is the experimental analysis of novel runner which has the ability to maximize output power and efficiency. ...

Saba Aleem1*, Mehvish Tahir2, Iram Sharif3, Muqadas Aleem4, Muhammad Najeebullah2, Ali Nawaz1, Amina Batool1, Muhammad Imran Khan1 and Waheed Arshad1

Principal Component and Cluster Analyses as Tools in the Assessment of Genetic Diversity for Late Season Cauliflower Genotypes
...ombinants in segregating generations, exploiting heterosis, and broaden the genetic base of the cauliflower germplasm.

...
Huan Yang1, Tingting Li1, Huimin Zhao1,2, Xiaoyuan Zhang1, Huiyan Xu1, Yangqing Lu1, Xingwei Liang1, Shengsheng Lu1, Xiaogan Yang1*and Kehuan Lu1*
...om parents to subsequent generations. In this research, to understand the growth characteristics of buffalo SSCs in vitro, methods for their isolation, enrichment, culture and preliminary identification were established. Testes from 3- to 6-month-old buffalos were digested with two-step enzymatic treatment to obtain isolated single cells and then enriched with a differential plating method. Isolated SSCs were cultured on STO feeder cells with SSCs cultu...
Abdul Waheed Solangi, Lei Zhang, Yunxia Cheng and Xingfu Jiang*
...and lifespan of the next generation in M. separata.
...
Ye Ge1, Chunmiao Zhao1, Weitian Xie2, Ying Liu2,* and Chunhou Xu1,*
... were obtained through regeneration, with a sporogenic rate of 69.1% and a colony number of 2.7×105 CFU/mL after an 80 °C high-temperature treatment. After 7 generations of fermentation, the average pH value was 4.47. The average number of colonies in the culture medium was 18.4. The production of protoplasts lays a foundation for research in microecological preparation.
...
Raheel Saqib1*, Muhammad Luqman2, Saleem Ashraf3, Tahir Munir Butt4, Abdur Rehman5, Imtiaz Hussain6 and Muhammad Umer Mehmood2
 
 
...amily farming employment generation takes place and unemployment issue prevailing in the society minimizes. The output of the family farm is high productivity and enhancement in farm income. Directly or indirectly, family farming leads to the food security situation and uplifts people’s living quality. All the rural farm families residing in district Mansehra served as the population for the study. In order to have a representation of the entire populati...

Muhammad Arslan Ibrahim1*, Aneeqa Aleem2, Farkhanda Manzoor2, Shahbaz Ahmad1, Hafiz Muhammad Zahid Anwar1, Talia Aroob2 and Mansoor Ahmad3 

... individuals in the next generation

...
Xinjian Wang1,2, Eryan Yang1,2 and Lizhi Zhou1,2*
...ain are facing wetland degeneration and habitat loss. Daily activity rhythm, time budget and foraging pattern of wintering swans are the important presentation of behavioral strategy in response to habitat variations. We studied the behavior of Tundra Swan wintering in the wetland of Huangpi Lake from November 2012 to February 2013. Wintering individuals and water levels were surveyed every day. Instantaneous scan and focal animal sampling was conducted to col...

Muhammad Khalid Mukhtar*, Sania Waliat, Shafaat Yar Khan, Naila Amjad

... used. Flies from the F1 generation were used in the bioassays. The results showed that LC50 for the lab strain against bifenthrin and dimethoate was 11.068 µg/ml and 8.879 µg/ml, respectively. LC50 for field strains, Bhalwal L1 and L2, against bifenthrin was 96.184 µg/ml and 130.903 µg/ml, respectively whereas against dimethoate it was 74.340 µg/ml and 84.531 µg/ml, respectively. The resistance ratios for field strains of l...

Aya El-Turkey1, A. K. El-Attar1, A. E. Aboulata1, B. Othman2 and K. A. El-dougdoug2

... were transferred into regeneration medium and genetically transformed with the HSV-2gD-PB21 binary vector through Agrobacterium co cultivation. Agro-inoculated tomato plants were tested for the HSV-2gD insertion and transcription using both PCR and RT-PCR and the results were successful in getting insert-containing tomatoes against HSV-2gD. Specific expression of the introduced antigen construct at the RNA level was detected by RT-PCR, using specific primers ...

Ahmed K. El-Attar; Samah A. Mokbel; Ali H. Hamed

...
elimination and regeneration of infected onion bulbs were determined.
...

A. B. Badr1 ; M. A. S. El-kady2; and Kh. E. A. Saker2

...ia , chloroplastes and degeneration of grana were also observed. Pinwheel
inclusions and associated virus particles are frequently found in the cytoplasm of
infected leaf cells.
...
Hadeer M. Mossa, Ausama A. Yousif, Emad A. Aboelsoud, Mahmoud El Gamal, Ahmed El-
Sanousi
...l aggregation and cell degeneration with titer of 105.5TCID50/ml,
DNA extraction and PCR for the candidate strain was performed using universal and specific primers
for virus identification and confirmation. The size of the produced amplicons was 192 pb for the
universal primer and 502pb, 1452pb for the specific primers respectively. Metagenomics is done to
evaluate a virus harvest for standardization by applying...
Shourok E. Aly 1, Karim Zaki1, Soad E. Elsayed2, M. Elgamal2, Ausama A. Yousef1, Mohamed A. Shalaby1
...ydroxide gel resulted in generation of 120-200 nm gel
structures followed by vaccine formulation showed enhancement of vaccine loading capacity. Animals
vaccinated using the enhanced formula were completely protected against RVF challenge virus and
produced higher RVFV neutralizing antibody titers.
Conclusion: The vaccine developed based on small particle vaccine formulation is an economic
solution th...

Zainab Iftikhar, Muhammad Arif, Iqbal Munir and Sajid Ali

...ld also be exploited for generation of further variability in Pakistani wheat germplasm for normal varietal development as a novel source of germplasm to reduce genetic homogeneity.

...
Bingjie Zhou1, Hitesh Bhagavanbhai Mangukiya1, Siva Bharath Merugu1, Fakhar-un-Nisa Yunus1, Yuchen Fan1, Zhenghua Wu1,* and Dawei Li1,2,*
...ent. Here, we report the generation of a fluorescent functional AGR2 fusion protein as a powerful visual tracking tool to trace the external function of AGR2. This bioactive and auto-fluorescent his-tag recombinant AGR2-DsRed (hAD) protein was constructed by linking human AGR2 C-terminus with the red fluorescent protein derived from Discosoma sp. (DsRed) througha flexible linker. It was expressed successfully in Escherichia coli (E. coli) ...

Syed Ismat Hussain1, Khalid Mehmood2, Mudassar Khaliq3, Habib Anwar1, Syed Muhammad Zaka4, Ateeq ur Rehman5*, Muhammad Shahid6, Syed Atif Hasan Naqvi5*, Ummad ud Din Umar5 and Muhammad Asif Zulfiqar7

... data for calculation of generations by accumulating progressive degree days was observed highly significant i.e., P>0.0001. In the present study, the accumulation of degree days for its forecasting was calculated from 1st January by using the metrological data and base line temperature and found 7 generations of pink boll worm to be found in all districts. Data for moths trapped in sex pheromone traps was noted as highly...

Sajida Batool1, Saira Batool1, Sitara Shameem1, Fatima Khalid1, Tahira Batool2, Summera Yasmeen1, Saima Batool3*

...epatic tissue, massive degeneration of hepatocytes, deformed nuclei of hepatocytes, highly disordered trabecular arrangement, vacuolar degeneration, diffuse necrosis, congestion and degeneration of the hepatic portal vein. Micrometric data indicated a significant reduction in themean number of hepatocytes and oval cells per unit area in ATZ treated group as well as significantly increased ...
Kai Jin1,2,3, Chen Chen 1,2,3, Xinyu Sun1,2,3, Caiye Zhu1,2,3, Mahmoud F. Ahmed1,2,3,4, Qisheng Zuo1,2,3, Jiuzhou Song4 and Bichun Li1,2,3*
...cessful transgenic goats generation was identified by testicular injection. The results showed a developmental time specific SCD1 expression in the goat mammary gland tissue and muscular tissue. The rate of positive expression of exogenic gene and exogenic protein in F2 transgenic mice was 30% and 6.67%, respectively, Moreover, muscular fat content in the positive group was significantly higher than the control group both in F1 and F2 (P > 0.05). The...
Kanwal Haneef1,2, Rakhshinda Habib1,3, Nadia Naeem1,3 and Asmat Salim1,*
...use of death globally. Regeneration of cardiac tissue with the use of stem cells has appeared as an effective cell-based therapeutic option. Mesenchymal stem cells (MSCs) are the potential candidates for cell therapy due to their ease of isolation, proliferation, anti-apoptotic and proangiogenic properties. MSCs have the ability to fuse with somatic cells in vivo and depending upon the microenvironment, the fusion products may perform tissue-specific fu...
Nazish Huma Khan1*, Mohammad Nafees2, Tooba Saeed3, Khaliq Ur Rahman4 and Adila Bashir2
 
...rviewed. The solid waste generation rate for the operating industries was 125,481 kg/ day. Only 33% of the waste generated is reused, and 26% is sold to the community at low cost. About 41% solid waste is thrown away as waste. Fifty percent of discarded waste (41%) is properly collected and disposed of. These wastes include wood (27%), paper (20%), glass/ceramics (16%), metals (16%), plastics (11%), rubber (6%), and sand/stone (5%). The waste management questi...

Muhammad Nauman1, Iftikhar Ali3, Nazir Ahmad1,2*, Fazli Ahad1 and Touheed Iqbal4

...e effective in the early generation for the improvements of these studied traits. Generally, cross combinations C-88 × C-89, C-93 × C-95, C-97 × C-88 performed better for oleic acid, glucosinolate content, and erucic acid, so that these segregants could be used for biodiesel and other industrial purposes.

...
Muhammad Mohsin Javed1*, Muhammad Azhar Nisar2 and 

Muhammad Usman Ahmad2 

... for evaluation of power generation. The MFC with 50 mM NaCl concentration showed maximum response and gave 88.9 W/m2 power densities and 569 mV of open circuit voltage. The results showed that NaCl, at its optimum level, plays an important role in increasing the bioelectricity and sustaining the internal resistivity. Six different pH parameters were subjected to check the effectiveness of the treatment on the power production. The maximum power pro...

Mazhar Ullah and Mohammad Sayyar Khan*

...ation resulted in high regeneration capacities. Amongst the carbon sources, sucrose was most effective both for callus induction and regeneration. ANOVA revealed significant differences (P ≤ 0.05) amongst the callusing media (CM). Maximum callus induction (48.55%) was achieved on CM-2 augmented with 2.5 mg L-1 2,4-D and 4% sucrose. All the carbon sources at 4% concentration in CM-2 showed maximum callus induction. However...
Nabila Rasheed1*, Bushra Waseem1, Kanwal Haneef2, Shumaila Usman3, Madeeha Sadiq1, Tabinda Urooj1, Sarah Tarique2 and Dabeeran Zeha4
...therapeutic agents for regeneration and are a valuable source for stem cell banking. Current investigation shows metabolic disorders are not only responsible for genetic problems and certain disease risk factors in adult life but also have adverse effects on perinatal environment. This study was designed for the comparative analysis of viability and healing properties of GDM affected WJMSCs (GDM-WJMSCs) with Normal controls (N- WJMSCs). Mesenchymal stromal cel...

Jiao Ma*

...the potential for self-regeneration and differentiation into cell types that can play an important role in embryogenesis and embryonic development. So far, seven types of cardiac stem cells with different molecular phenotypes and differentiation potentials have been discovered and studied. Increased proliferation and differentiation of these cells in areas of cardiac ischemia is a significant factor in the repair and enhancement of heart injury. This role of e...

Mohamed S. Hussein1*, Hanan A. Fahmy2, Ashraf A. Abd El Tawab3 

...s observed against first generation (86.1% for nalidixic acid, and 81.9% for flumequine), and lowest rate against levofloxacin (33.3%). A total of 24 isolates, dsplaying high resistance to at least 5 fluroquinolone antibiotics, were then screened for plasmid-mediated quinolone resistance (PMQR) genes qnrA, qnrB, qnrS, qepA and aac(6′)-Ib-cr by PCR. The results revealed that 22 isolates (91.7%) harboured at least one PMQR gene, with qnrS being the most fr...

Abdul Haleem1*, Ghulam Hassan1, Arshad Iqbal2, Fahim Ullah Khan3, Muhammad Sajid3, Farhad Ahmad4, Rafi Ullah Khan5 and Mohammad Ilyas2

...ssive segregant in early generation. To assess genetic variability, broad sense heritability and traits varied from, 36 lines of wheat were field tested in RCBD with three replications. The experimental materials include twenty eight F2 population and eight parents. Data showed considerable genetic variation amongst the studied lines, parents, F2 progeniessand parent versus F2 progenies for all the studied traits. Among parents, best lines were Atta-Habib for ...
Zane Vincevica-Gaile1, Karina Stankevica1, Maris Klavins1, Roy Hendroko Setyobudi2, Damat Damat3*, Praptiningsih Gawawati Adinurani4, Lili Zalizar5, Muhammad Zul Mazwan6, Juris Burlakovs7
Didiek Hadjar Goenadi8,9, Rista Anggriani3 and Aamir Sohail10
 
 
...nt assignment for future generations. The necessity for peat-free soil amendments is also directed by the targets of circular economy and environmental sustainability goals, leading to reducing or abandoning the use of fossil resources and paying attention to waste utilization as secondary raw material. This paper aims to discuss general features of peat-free soil amendments as well as provide efforts into the use of secondary raw materials such as biomass ash...

Aasma Younas*, Ijaz Iqbal and Atif Akbar

Hafiz Ghulam Muhu-Din Ahmed1, Aziz Ullah2, Muhammad Asim Bhutta3*, Amna Bibi3, Hafeez-ur-Rehman4 and Umar Farooq4

...dditionally used in next generations for improved morphological indices conferring drought-tolerant genotypes.

...

Rafiqul Islam1, Nasrin Sultana1*, Md. Abu Hadi Noor Ali Khan2 

...on showed myofibrillar degeneration and vacuolation in the DEX groups with an extensive degree at days 21 and 28 of the trial. It can be concluded that the DEX treatment affect the serum biochemical markers as well as the morphologic and morphometric parameters of the broiler heart.

Keywords | Dexamethasone, Broiler, Heart, Biochemistry, Morphometry 

...

Naila Shahzadi1, Hafiz Muhammad Tahir1*, Shaukat Ali1, Muhammad Farooq Bhatti2, Azizullah1, Shafaat Yar Khan3, Abdul Khaliq4

...mily manpower for income generation via indoor activities. It has potential to provide a livelihood for the poor rural families and can play a crucial role to uplift the economy of our country. Unfortunately, this industry has not been on the list of priorities of our Government. Currently, Pakistan is importing silk from other countries to meet the demand of local market. Nutritional background of larval stage (1st, 2nd and 3rd instars etc.) significantly inf...

Nazakat Nawaz1, Nasir Mahmood Cheema2*, Malik Muhammad Yousaf3, Muhammad Jahanzaib1, Mubashir Ahmad Khan1 and Muhammad Munir4

...d was continued up to F5 generation. The generations, F2 to F5 were raised for consecutive selection as single plant progeny rows along with parents. PG-1090 being medium duration showed overall higher mean yield (4912 kg ha-1) in preliminary, advance, national uniform yield and on-farms trials compared to other lines and check cultivars BARD-479 and Golden. Its attributes include 70% shelling, 100-kernel weight 66g, 20-pods...

Honnakerappa S. Ballari1 and Shashikant S. Udikeri2*

...nineties. Hence many new generation pesticides are in use widely. To know the status of different insecticides belonging pyrethroid, ogranophaopsahte and carbamate molecules monitoring was exercised using populations of H. armigera collected from different agroclimatic situations in Karnataka state, India. An abstinent to tremendous resistance was documented for synthetic pyrethroids, carbamates and organphosphates insecticide despite under use of these molecu...

Muhammad Idrees1, Bashir Ahmad2, Muhammad Waqas1, Syed Muhammad Mukarram Shah3 and Saad Ahmad Khan4

...is were selected for the generation of pharmacophores. The validated pharmacophores model of all the four proteins, generated on the basis of ligand base, were selected for further screening of ZINC drug like database. As a screening results 486 structurally diverse hits for katG, 542 for PncA, 112 for rpoB and 365 for gyrA were mapped and filtered via Lipinski’s rule of five. Finally, on the basis of docking score and binding interactions, ten small mol...

Wei Cui1, Yanwei Du1, Lijuan Jiang1, Yan Wei1, Yuguo Li1, Wenfeng Zhang1* and Ling Zhang2*

...closely related to the degeneration and apoptosis of hippocampal neurons. Buyang Huanwu Decoction (BHD) is a classic traditional Chinese medicine prescription, which has the functions of benefit qi, activing blood circulation and dredging collaterals. To investigate the protective effect and mechanism of BHD on hippocampal neurons in diabetes, a high glucose (HG) induced PC12 cell injury model was established, cell proliferation and apoptosis were detected. Th...

Jawad Abdullah Butt1*, Yasmin Nergis1, Ahmad Hussain2 and Mughal Sharif1 

...al data. For electricity generation, the utilization of Thar coal assets is not limited to their burning, but additional steps must be taken to utilize the tools to reduce the pollution volume of coal and its harmful impacts on the environment. Innovative tools with advanced efficacy and fewer environmental impacts are essential to handle these low-rank coals and to transform them into energy e.g., Circulating Fluidized Bed Combustor (CFBC) and other Clean Coa...

Abdul Majeed1, Zhenlin Liang2, Lixin Zhu2, Chunli Liu2, Muhsan Ali Kalhoro1,* and Faisal Saeed1

...ainable level for future generation.
...

Phassakon Nuntapanich1*, Hathaichanok Nuntapanich2 and Woraman Maicharoen3

...transferred from the old generation as local wisdom. It is the tools considering as an appropriate technology, which enables the ecosystem to continually provide services to the farmer (e.g., local food security, household income, surface water supply for rice production and enhance soil nutrients for rice crop) without damaging the ecosystem’s capacity to provide the services. The marketing channel can be divided into three types are 1) travel-customer,...

Barirah Rehman Talpur1, Zaheer Ahmed Nizamani1*, Imdad Hussain Leghari2, Mansoor Tariq1, Aisha Rehman3, Shahnawaz Kumbhar1 

...nd sinusoids and fatty degeneration of hepatocytes. Kidney tissues of both rabbits and broilers revealed marked shrinkage of glomeruli with widened bowman’s spaces along with inflammatory cellular infiltration. It is concluded that high dose (200mg/l) of Sodium Fluoride causes liver and kidney dysfunction in both species along with lesions in digestive system of broilers.

Keywords | Fluorosis, Rabbits, Broilers, Liver, Kidney 

...

Mohamed El-Henfnawy*, Essam A. El-Gendy, Ahamed M. El-Kaiaty, Mostafa Helal 

... was deceased at the 6th generation of selection, it has been retrieved at the 10th generation of selection.

Keywords | Local chicken, Body weight, Selection, Growth rate, Sustainability  

...
Emtenan M. Hanafi1*, Fouad M. Tawfeek2, Walid S. El Nattat1, Moetazza M. Alshafei3, Seham S. Kassem3, Kawkab A. Ahmed4, Enas N. Danial5, Hagar Elbakry3, Hoda S. El-Sayed2
...on declared testicular degeneration in G1 and G3 and a high spermatogenesis in G2 compared to control group. It was concluded that spirulina may act as health potentiator but also, may negatively affect the male reproductive performance. Special care should be paid for the dose and frequency of administration of any polyphenol or health potentioators.
 
Keywords | Spirulina platensis, Bifidbacterium longum, Spermatozoa profile, Mal...

Tu Thi Minh Tran1*, Diep Hoang Tran1, Thuong Thi Nguyen2, Tomas J. Acosta3, Takeshi Tsuruta4, Naoki Nishino4, Hai Thanh Duong5

...onment, Microbiota, Next generation sequencing, Tropics
...

Samia Azad1, Iram Liaqat1*, Riffat Iqbal1 and Uzma Rafi2

...e observed. Pronounced degeneration of liver tissues, severe vacuolization, remarkable cirrhosis, necrosis and karyolysis was observed in live tissue of fish exposed to high Cd concentrations (0.6-1.0ppm). In conclusion, long term exposure of Cd at high concentrations showed toxic effects on intestine, kidney and liver of Rohu (Labeo rohita) and confirmed it harmful heavy metal for aquatic environments.

...

Arfan Ahmed Gilal1*, Lubna Bashir Rajput1, Muhammad Ibrahim Kubar1, Ghulam Murtaza Kaleri2, Tanzeela-ul-Zahra1,3, Muhammad Ishaque Mastoi4 and Zeeshan Rasheed1

...pproximate and corrected generation time of FAW between leaves and stems. Innate capacity of increase (rc) and intrinsic rate of natural increase (rm) recorded on stems (0.1237±0.0032 and 0.1248±0.0033, respectively) were higher than leaves (0.1027±0.0025 and 0.1034±0.0026, respectively). Finite rate of increase (λ), doubling time (DT) and net reproductive rate (Ro) observed on maize stems (0.3363±0.0086, 5.61±0...

Abdul Hafeez Mastoi1, Muhammad Rashid Nizamani2, Shafique Ahmed Memon3, Jun Jiang1, Xiang-Shun Hu1* and Tong-Xian Liu1*

...e, finite rate increase, generation time, and fecundity of A. pisum was observed at 27°C, regardless of pea cultivar. In decreased as temperature increased at and above 30°C for each cultivar. Furthermore, differences among cultivars were often detected at 27°C and 30°C, but not at higher temperatures. Our results indicated that.

...

Zulqarnain Haider1*, Muhammad Akhter2, Syed Sultan Ali1, Tahir Latif1, Rana Ahsan Raza Khan1, Awais Riaz1, Tahira Bibi1, Muhammad Ijaz3, Qasim Raza1, Mohsin Ali Raza4, Samina Sarfaraz1, Muhammad Iqbal1 and Muhammad Rafiq1

... investigated in advance generation. Triplicated randomized complete block design (RCBD) was used during three consecutive years from 2016 to 2018 and the data were subjected to combined ANOVA, correlation, principal component, GGE biplots in order to demonstrate the stability and performance of these advance Basmati lines. A highly significant and exploitable level of genetic variability was found existed among tested inbred lines. Higher broad sense heritabi...

Muhammad Shafiq1, Tehseen Ashraf2*, Sehrish Mushtaq1, Naveeda Anjum3, Muhammad Asim4, Muhammad Aqeel Feroze3, Malik Abdul Rehman4 and Marja Aziz3

...otocol for chili plant regeneration with hypocotyl and cotyledon explants was established. The study was conducted to observe the effect of genotypes, culture conditions and growth regulators on plant regeneration of chili pepper genotypes (Seedex Pepper (SP), Loungi, Tatapuri, and Sanam) grown in Pakistan including. For both hypocotyl and cotyledon explants, SP was found to be the most sensitive among the tested genotypes t...

Muhammad Ikram Ullah

... The combination of next-generation sequencing has facilitated the identification of genes in complex disorders like alpha-mannosidosis.

...

Bnar Shahab Hamad1, Bushra Hussain Shnawa1*, Rafal Abdulrazaq Alrawi2 

...hydatid cyst were cell degeneration, necrosis, hemorrhage, congestion, and fibrosis. The findings revealed that the CD3 T cells were the most predominant inflammatory cell in hepatic mice tissue. Also, CD4 Helper T cells, CD8 Killer T cells, CD20 memory cells, and CD68 macrophages were detected in the infected mice. Most samples of mice expressed a different level of tissue necrosis where anti-caspase-3 was examined. Additionally, several mast cells in the mic...

Akbar Hayat1*, Ehsan Ul Haque1, Marayam Nasir2, Rab Nawaz3, Tariq Mahmood4 and Sohaib Afzaal1

...xotic material of latest generation. This endeavour led to the sound recommendation of sweet oranges like Rhode Red Valencia and Sun Star in the two years of study. In case of taste imparting characteristics like TSS, acidity and their respective ratio in the Rhode Red Valencia TSS 11.4 %, Acidity 1.05, TSS/Acid Ratio 10.97, Cara Cara produced TSS 10.95, Acidity 0.74, TSS/Acid Ratio 14.81, Amber Sweet TSS 10.95, Acidity 1.03, TSS/Acid Ratio 11.11, Sun Star TSS...

Chattida Panprom1, Nakrob Pattanapon1, Wannisa Meepoo1, Soontaree Petchdee2* 

...ate to severe valvular degeneration during general soft tissue surgery. Three client-owned dogs with valve degeneration stages C or D who underwent general anesthesia for surgical treatment were included in this study. All dogs in this study were assigned to receive diazepam 0.3 mg/kg body weight, alfaxalone 2.5 mg/kg body weight, and a perioperative fluid rate of 5 ml/kg/hr. An appropriate assessment before and during surge...

Ahmed Rizk1, Gomaa Said Ramadan2*, Alaa Eldin Abdou3, Ossama Ahmed El-Weshahy1, Omer Sayed Rashed1 

...on was applied for three generations. Body weight at sexual maturity (BWSM), age at sexual maturity (ASM), and egg production traits (EP) from 36 - 42 weeks of age were also applied. Our results showed that the average body weight for Tanta G-1 and Mamourah chicken strains was 866.45 grams and 558.75 grams in the first generation. In the second generation, the Tanta G-1 line’s body ...

Sumaria Maqsood1*, Muhammad Ali 2, Amna Shoaib3, Shahbaz Ahmad2 and Noor-ul-Ain2

...ing of S. litura for six generations for laboratory and field experimentation.

...

Sumreen Begum, Atta-ur-Rahman and Asmat Salim*

...pment is imperative to regeneration. The purpose of this study is to analyze systematic identification of genes with respect to nephron lineage and pluripotency during postnatal renal development and at adult stage of rat kidney. In the current study, the mRNA levels of nephron genes were analyzed by reverse transcriptase PCR in neonatal and adult rat kidney tissues. These genes were divided into three categories. Group 1: renal multipotent progenitor genes; G...
Istkhar† and A. K. Chaubey†
...ective juveniles and 1st generation males showed close resemblance with S. abbasi, S.
thermophilum and S. pakistanense however, the body length was varied (583mm vs 541mm, 555 mm and 683 mm,
respectively). The morphometrical characters and life history events placed the present specimen near to the S.
abbasi. Results obtained through the phylogenetic utility of maximum parsimony, maximum likelihood and
neighbour ...

A. A. Galal1,2, S. F. Abou-Elwafa1,3, F. J. Kopisch-Obuch1 and C. Jung1

.../div>
during early generations of cultivar development.
...
Saleh Aljubran, Shaker Al-Suwaiegh, Yousef Alyousef, Sulaiman Alhajri, Mohammed Alghareeb, Abd El-Nasser Ahmed Mohammed*
...uce the interval between generations, therapy of diseases and conservation of endangered mammalian species. Practically, current reproductive biotechnologies are species-specific because of differences in estrous cycle, seasonality, structural anatomy, gamete physiology and site for semen deposition or method of embryo transfer. Therefore, this review was conducted to collect and consolidate the current knowledge of assisted reproductive techniques of males an...

Muhammad Adeel Qureshi1*, Raza Ahmad2, Bilal Ahmed1, Tanzim Ullah Khan1 and Muhammad Yasin3

...us induction and plant regeneration of potato (Solanum tuberosum L.). The experiment was carried out in complete randomized design (CRD). Leaves and internodes of potato cv. Desiree were used as explant for callus induction and plant regeneration. Two types of callus induction media (CIM) were used, i.e. CIM1 and CIM2 with concentrations of 2, 4-D 2mg/lit and 3 mg/lit respectively. Among the two different callus induction me...

Shah Murad Khan1, Hamayun Khan1, Younas Muhammad1, Haq Aman Ullah1*, Muhammad Tariq Tunio2, Ali Gohar2 and Fazli Rabbani

Abdirahman Barre*, Karanja D Njuguna, Bebora Lilly Caroline and George Chege Gitao

...estion 4 (2.5%), fatty degeneration in liver 3 (1.8%) and haemorrhages in kidney1 (0.6%). In conclusion, brucellosis is prevalent in camel in Garissa County. Further extensive research should be done in the whole country. With respect to picking positive cases, RBPT is recommended as a screening test, since it is cheap, quick, and easy to carry-out. The other three can be used to establish respective antibody titres. The organs condemned at inspections are due...
 
 SADAF SARFRAZ1*, SAFDAR AMEER1, REENA AMBREEN1, SHOMAILA SIKANDAR 2, SHAISTA NAWAZ3 AND YASIR SALEEM
...ehyde, owing to its acid generation, acid tolerance and virulence gene expression has gained a considerable attention. Keeping in view its beneficial aspects, the present study has been conducted to investigate the contents and compare the nutritional and antimicrobial activities of Cinnamon collected from various regions of Asia. In this study, antimicrobial activity of cinnamon was estimated using well diffusion me...

Chenchen Liu1,2, Tong Wang1, Muhammad Khan3*, Xiaolin Cui2 and Yongming Li1,2*

...f apoptosis includes ROS generation, G2/M phase arrest and inhibition of aerobic glycolysis. Inhibition of glycolysis was found to be linked with down-regulation of lactate dehydrogenase A (LDHA) and glucose transporter-1 (GLUT1). Finally, ALT effectively suppressed growth and induced apoptosis in cisplatin resistant A2780/CR cells. Taken together, our findings suggest that ALT could be developed into a lead for effective treatment of ovarian cancer.

...
Ayesha Ahsan1, Rabia Arif2*, Samina Nazir1, Muhammad Saleem2 and Memunna G. Shahid1
...ix strains and F3 and F4 generations of Sordaria fimicola collected from the Evolution Canyon-1. Sequenced products of 464 bp of tubulin gene and 548 bp for PKC gene were aligned to observe the genetic variations between the eight parental strains of S. fimicola and reference sequence of S. fimicola. Total six polymorphic sites were observed in case of tubulin gene out of which 5 sites were common among strains isolated from the s-slope of Evolution Canyon (EC...

Muhammad Akram¹,²*, Rashid Mahmood³, Fahim Arshad4 and Umer Farooq Gohar5

...er potential for shoot regeneration and proliferation in the growth regulator-free MS liquid medium (95.25%) as compared to the solid medium (89.00%). Shoot cultures remained viable for up to 15 days without refreshing the medium and could be sustained for 12 months when sub-cultured every 15 days. Invigoration of albino shoots with fresh MS basal medium resulted in multiple green buds, which successfully transformed into 54.60 and 652.78 healthy shoots in 30 ...
Muhammad Rizwan1*, Bilal Atta1,  Muhammad Arshad2, Sohail Akhter3
Muhammad Tahir3, Misbah Rizwan1, Muddassir Ali1 and Arshad Makhdoon Sabir1
...te of increase, and mean generation time (T). However, it had significantly reduced the fecundity of females from 294.00 to 262.43 eggs/female and net reproductive rate (R0) (174 to 91.85 d). Our results showed that C. septempunctata had adopted to manage λ cyhalothrin and it could be used in experiments involving C. septempunctata as a natural biocontrol agent.

...

Najamuddin Solangi1*, Mushtaque Ahmed Jatoi1, Adel Ahmed Abul-Soad2, Abdul Aziz Mirani1, Muhammad Aslam Solangi3 and Ghulam Sarwar Markhand1

...yogenesis and plantlet regeneration in commercially important date palm cvs. Begum Jungi and Ajwa. Spikelet explants of spathes (avg. 17, 28, 32 cm) excised at different intervals were used as initial explants. Results revealed that sterilization of spathes with 50% sodium hypochlorite (NaOCl) solution resulted in significantly highest survival, lowest mortality and contamination in spikelet explants. The spikelet explants obtained from immature spathes (avg. ...

Rahma Boukarine*, Leila Hamdi and Kamel Khelili

...ecrosis and glomerular degeneration, the effect of ESAE was effective in modified these damages into semi normal.To conclude, xylene administration induced hepatotoxicity and nephrotoxicity in wistar rats, while the combination of this solvent with rocket aqueous extract (Eruca sativa) attenuated this toxicity thanks to its antioxidant property.

...

Yue Guo1,2*, Hui Zhang1, Chun Sheng Wang1 and Hong Chang Zhou1

...quenced through the next-generation sequencing (NGS) technology. Sequencing data were assembled into unigenes and transcripts. Finally, all unigenes and transcripts were annotated by querying the NR, Gene Ontology (GO), COG and KOG databases.A total of 71047 unigenes and 106652 transcripts were assembled. A. cantonensis was successfully annotated by the NR and GO databases, resulting in 8107 unigenes and 16105 transcripts. Meanwhile, 10422 unigenes and 20974 t...

Abdul Hassan1*, Arshad Farooq1, Muhammad Ishaq2, Ghulam Sadiq2 and Asif Nawaz3

...rm employment for income generation and reducing hiring of labor for farm activities while financial strategy was related to sale of perennial crops and sale of livestock. The study suggested for sustainable smallholder agricultural development programs along with farmers’ facilitation by giving interest free loan and digitalization to update timely information regarding weather and markets for improving rural livelihood.

...

Nawfal Hammadi Jasim1, Yasmeen Jassim Mohammed2 , Jala Amir Salman Alahmed1, Majdy Faisal Majeed3* 

...tral vein, hepatocytes degeneration, nuclei pyknotic, sinusoids dilation, and slight inflammation, while group 2 revealed severe damage mainly , lost the typical polymeric shape, hepatocytes alteration, hepatocytes vacuoles, necrotic foci, inflammation cells aggregation, sever dilated and congestion of sinusoids and nucleus pyknotic. Conclusion: These findings demonstrated that the MPH overdose induced free radical-mediated oxidative stress, through an increas...

Ahmad-Ur-Rahman Saljoqi1, Imtiaz Khan1*, Ijaz Ahmad1, Javed Khan2, Shahid Sattar1, Bashir Ahmad Khan and  Muhammad Salim

... The total mortality per generation (K-value) from all immature stages was 0.26. The total female fecundity was 379.0 eggs and the fertile eggs ratio were 144 and net reproductive rate (Ro) was 2.57 eggs per female/day. The intrinsic rate of natural growth (rm) was 0.34 female per female per day, with a mean generation time (T) of 3.06 days. 1.404948 females per female per day was the limited rate of growth (λ). The D...

Hafiz Muhammad Walayat Ali1, Hafiz Basheer Ahmad1*, Zaheer Ahmad Nazar2, Muhammad Akhlaq Mudassir1, Mahmood-Ul-Hasan1, Abdul Khaliq1 and Muhammad Shahzad Afzal1

...ld be effective in later generations for the improvement using these traits.

...

Zahra Abdulameer Al-Zayadi1, Hana Kadum Shanan1, Al Salihi Karima Akool2

...groups, accompanied by regeneration related to the treatment dose. Severe damage comprising necrosis of the hepatic cells, renal tubules, congestion, and infiltration of inflammatory cells was seen in the chemotherapy-treated group and mice suffering from cancer without treatment. This study also revealed variations in serum liver enzyme values between treatment groups. The values of ALT, AST, and ALP (U/L) evaluation in control groups were ˃ 29.01±1.8...

Mati Ullah1*, Muhammad Rizwan2, Ali Raza3, Xianlin Zhao4, Yanling Sun4, Sarah Gul5, Muhammad Ihtesham Waheed6, Muhammad Nadeem Khan7, Alvina Gul8, Sami Ullah Jan9* and Chao Huang4*

...t samples using the next-generation sequencing approach. The GC contents of the characterized strains were in the range of 46.03 to 46.52% while the protein-coding sequences (CDS) were in the range of 2544 to 2888. The pan-genome analysis of the three strains identified a total of 5449 genes with 377 as core genes. The functional characterization by subsystem category distribution analysis revealed “Carbohydrates” is the largest subsystem followed ...

Munir Ahmad1, Abdul Ghaffar1, Riaz Hussain2* and Rifat Ullah Khan3*

...n showed renal tubular degeneration, widening of Bowman’s space and necrosis in kidneys. Different histopathological lesions in liver of treated test specimens including edema, hemorrhages, atrophy of hepatocyte and hepatocyte having eccentric nuclei. In the brain, different histological alterations like necrosis and degeneration of neurons, and microgliosis were seen, whereas the heart of treated fish showed hemorrhag...

Muhammad Salman Ikram1, Tahir Mehmood1,2*, Sehrish Firyal3, Huma Sattar4, Shagufta Saeed3, Fareeha Nadeem3 and Muhammad Imran Mahmood Khan5

...l the importance of next generation sequence (NGS) as an advanced technology in forensic genetics. This manuscript also demonstrates the unique features of Y-STR markers and their different application in forensic like significance of population genetics and genealogical pattern of Y-chromosome STRs diversity in different regions of world which helps to understand the pattern of variation in DNA within and between species, importance of Y-STR in relation of it...

Mehwish Malik1*, Zanib Sadia2, Muhammad Sajid3, Hammidullah1, Yasir Amin1, Zubair Ali1 and Sohail Ahmad1

...;">Introduction of third generation cephalosporin in 1980s has overcome the problem of antibiotic resistance and most of the diseases were treated properly at that time, but the current situation of excessive use of these antibiotics in the treatment plans of both human and veterinary medicine makes them resistant to many bacteria including ESBL E. coli. Resistance of microbes to antibiotics is becoming an alarming situation throughout the world and the infect...

Beenish Shahid1* and Muhammad Ijaz Khan2

...ficant decrease in the degeneration of the oocytes (P=0.001). The addition of insulin was not found to be effective for in vitro maturation. It is concluded that the addition of E2+rhFSH in culture media was found to be the best combination of hormones for in vitro maturation of denuded buffalo oocytes.

...

Yakun Ge

...ic therapy increased the generation of ROS to inhibit PI3K/Akt/mTOR signal transduction, increase the expression levels of pro-apoptotic proteins Bax, caspase-3 and caspase-9, inhibit the expression level of anti-apoptotic protein Bcl-2 and the epithelial-mesenchymal transition of cancer stem cells, reduce the proliferation ability of cancer stem cells, and increase the apoptosis of cancer stem cells.

...

Afifatul H.A. Adilah1, Junun Sartohadi2* and Suci Handayani1

...erent purposes of income generation. The differences in canopy characteristics between the two plants significantly affect the production of runoff. Field evidence is needed to support it as a suitable plant for soil and water conservation efforts. The study was conducted using a field survey method equipped with soil characteristic measurements in the laboratory. The data collection process began with a study of the landscape of the research area which was di...

Mohamed Mahrous Amer1*, Hanaa Sayed Fedawy2, Hoda Mohamed Mekky2, Khaled Mohamed Elbayoumi2, Ahmed Ali El-Shemy3, Mohamed Abd El-Rahman Bosila2

...infiltration, hydropic degeneration of the hepatocytes and congested splenic sinusoids. While treated groups showed limited skin inflammatory condition at the site of injection and return of skin to normal color and thickness. Doxycycline+ colistin combination helps in reduction of lesions in treat infected birds, with marked improvement in measured parameters. We recommended active actions to prevent causes and factors helping in including cellulitis, regular...

Muhammad Nasir Bhaya1,2* and Hikmet Keles2

... hyperemia, epithelial degeneration, swelling, cystic dilatation and luminal proteinaceous material in tubuli, congested and hypercellular glomeruli and also inflammatory cells infiltration in the cortical and medullary area in CP group. Significant decrease of pathological lesions was found in CP+EA groups especially in the CP+EA75 group. In immunohistochemical sections, 8-hydroxy-2-deoxyguanosine (8-OHdG) and hypoxia-inducible factor-1 alpha (HIF-1α) r...

Nasratullah Baloch1, Naeem Tariq Narejo2, Hamida Narejo3, Muhammad Farooq Hassan4, Ghulam Abbas5, Shahnaz Rashid5, Muhammad Hanif Chandio6, Faheem Saddar7 and Majida Parveen Narejo8

...ood resources and income generation of the local people.

...

Sameh Abdel-Moez Ahmed Amer1*, Aly Mohammed Ghetas1, Asmaa Mahmoud Maatouq1, Hagar Magdy Ahmed1, Khaled Mohamed El-Bayoumi1, Mohamed Abd El-Rahman Bosila1, Ahmed Ali El-Shemy2

Razia Sultana1, Shinawar Waseem Ali1*, Ghulam Murtaza2 and Shahid Mahmood2

... using the advanced next-generation sequencing (NGS) method. Yogurt samples were collected from open-air shops located in different areas of Pakistan. All yogurt samples were mixed to make one composite sample. DNA was extracted from yogurt using the phenol-chloroform (organic) method. Extracted DNA was used to perform NGS/Illumina high-throughput sequencing of hypervariable regions (V3 and V4) of the 16S rRNA gene. In the composite yogurt sample, 100% bacteri...
Jaffar Hussain*, Zeenat M. Ali and Syed Farman Ali Shah
...esel. The 1st generation feedstock would create the food shortage. The second-generation yield was comparatively less and from third generation feedstock the process was complicated and expensive. The fourth-generation feedstock produced from genetically modified algae or by artificial photosynthesis in plants to produce the raw material for b...

Lu Liu1, Xiang Zhao2, Yue Qin2, Tianxiang Gao3 and Tianyan Yang3*

...ed and assembled by next-generation sequencing techniques. The complete mitochondrial genome of Lophius litulon contained 13 protein-coding genes (PCGs), two ribosomal RNA (rRNA) genes, and 22 transfer RNA (tRNA) genes. The total length of the mitochondrial genome of L. litulon was 16,430 bp, and the overall base composition of the mitochondrial genome was 26.96% A, 30.13% C, 17.58% G and 25.33% T. Our sequence is consistent with the mitogenome (NCBI ac...

Sri Suharyati, Tiwi Aries Pani, Akhmad Dakhlan, Syahrio Tantalo, Kusuma Adhianto*

...n the growth of the next generation. This research was conducted in Gisting and Sumberejo Subdistricts, Tanggamus District and we aimed to determine the body weight and body sizes of Saburai goats doe who have single and twin birth types. Data collection was carried out on 62 Saburai goats doe in the study area. Data were analyzed by t-test. The results showed that the average body weight, body length, shoulder height, chest circumference, chest width, chest d...

Moazzam Baig*, Sohaib Ahmed and Arz Muhammad Umrani

...animals harm the local regeneration as well as the local land cover. The proposed Hypothesis shows that the significant relationship between Dependent and Independent variables i.e. Forest Degradation and Socio-Economic Factors.

...

Roberto Gallegos-Acero1, Ali William Canaza-Cayo2,4*, Francisco Halley Rodríguez-Huanca1, Rubén Herberht Mamani-Cato3, Abigail de la Cruz1, Júlio Sílvio de Sousa Bueno Filho4 

... number of ancestors (), generation interval (GI) and the pedigree completeness, the ENDOG program v.4.8 was used. The F and AR were 0.06% and 0.40%, respectively, The number of ancestors that gave rise to the reference population was 288, the for the reference population was 132. The was 338 animals. The average generational interval was 5.53 years, being higher in the gametic pathways: sire-daughter and sire-son. The pe...

Haneen Imad Al-Sultani1*, Ahmed Obaid Hussain1, Hazar Shakir Saleh2 

...hemorrhage, glomerular degeneration, fatty changes, cysts and vacuoles in the renal tubule cells and lymphocytic infiltration in the kidney tissue with gradual increase in rosuvastatin concentrations 10, 20 and 40 mg/kg, respectively. Conclusion: It was concluded in the current study that the use of rosuvastatin in high doses causes nephrotoxicity.   

...

Ashfaq Hussain1, Javed Khan2, Ammara Blouch3, Ahmad-Ur-Rahman Saljoqi1, Ashraf Khan4,5* and Zaheer Sikandar6

...al K value for the whole generation was 0.33.

...

Farhana Umer1, Muhammad Sheryar2 and Sangam Khalil3*

...nsfers from power plants generation to substations then to consumers and its own environment is tremendous. Among various hazards, the overhead wires associated with power lines are the most fatal hazard to birds. The power lines and poles have caused fatal risks for birds and have affected their habitats significantly. Dangerous types of power poles in the middle voltage lines which have small distances between the lines and short insulators cause short-circu...
Muhammad Javed Iqbal1, Farah Rauf Shakoori1*, Bushra Muneer2 and Abdul Rauf Shakoori3

Hualong Jiang1, Tao Li2,3*, Jing Xiang3, Hanqing Yang3 and Maolin He3

... the present study, next-generation sequencing and bioinformatics analyses were performed to compare changes of microeukaryotic communities in local sediments influenced by sea-crossing bridge construction. Relatively low levels of alpha diversity and high levels of beta diversity were observed in samples influenced by bridge construction (group EG). The decreased abundance of Chloroplastida and increased abundance of Animalia in group EG suggested that engine...

Oghenebrorhie M. Oghenochuko1,4*, Olubukola T. Adenubi3, Olusola L. Ajayi3, Fakilahyel M. Mshelbwala3, Johnny O. Olukunle3, Samson A. Rahman3 and Godfrey N.O. Ezeri2

...ging effect on organs. Degenerations were observed in the hepatocytes and epithelia cells in the kidney in some treatments especially in bath treatments. In conclusion, onion bulb showed no toxicity in the blood parameters but dose should be considered to avoid harmful effect on liver and kidneys.

...

Rasema Majeed, Alaa Kamil Mahmood* 

...ngested blood vessels, regeneration of islet cells. fourth group was administered 81.7 mg/kg BW of ginger ethanolic extract loaded with chitosan nanoparticles orally for 45 days and showed normal section of islet cells, regeneration of islet cells also showed no clear lesions in the islet cells. whereas fifth group was administered 81.7 mg/kg of chitosan nanoparticles orally for 45 days and showed few destructions and vacuol...

Zein Salwa N; Abd El-khalik, Samaa; Khatab  , Eman A.A.H and Azzam4,Clara R.

...a 60Co source. Ml and M2 generations were sown at the experimental fann of the Agricultural Res. Center to induce variability in the sunflower genotypes; Giza 102 and Sakha 53, which could be resistant to TMV-S. The statistical analysis indicated significant differences among irradiation doses on plant height; all used doses increased plant height comparing with the control. Inoculation with TMV-S caused decreases in plant height over all other factors. Number...

Amer, H.M.; Hussein, H. A.; El-Sabagh, I. M.; El-Sanousi, A. A. Saber,M.S. and Shalaby, M. A.

...g PCR and propagated for generation of high-titer viral stocks. In vitro expression studies utilizing the recombinant baculoviruses were conducted and revealed high-level expression of N protein as indicated by its distinct reactivity in immunofluoresence, solid phase ELISA and Western blot.

...

Sabry Y. M. Mahmoud; Maher H. Hosseny and Mamdouh H. Abdel-Ghaffar

...ct on potato yield and degeneration of seed tubers. This study aimed to eliminate potato virus Y (PVY) by tissue culture technique using different therapies, such as thermo-, chemo- and electrotherapies. Potato plants cv. Diamond cultivated at Faculty of Agriculture farm, Sohag University were tested by direct antigen coatingenzyme linked immunosorbent assay (DAC-ELISA) using antisera against PVY, Potato virus X (PVX) and Potato leaf roll virus (PLRV). The res...

A. A. Kheder1; I. A. M. Ibrahim2; H. M. Mazyadl

...hown. Extensive severe degeneration of chloroplast and mitochondria structure as well as development of cell wall protrusions was observed.

...

Huda M. Hamid1, Fadia W. Al-Azawi2* and Zaid F. Makki3

...ion planning, hydropower generation, and management of drought and water scarcity. To analyze the hydrology characteristics of Iraq dams and to conduct this analysis, remote sensing and GIS techniques have been used. The analysis of hydrology characteristics in Iraqi dams is crucial to ensure sustainable water resource management. This research provided a comprehensive overview of the current state of hydrology characteristics in Iraqi dams and to identify are...

Ahmed Kadhim Munahi1* , Hameed A. Al-Timmemi2 

...rticles on spinal cord regeneration in dogs. For this objective, sixteen healthy mongrel dogs were used. They were divided into two equal groups (n=8) at random. All dogs underwent dorsal laminectomy and left lateral hemisection at the level of the second lumbar vertebra. In the control group, the hemisections were treated with 0.2 mL of phosphate buffer saline. Chitosan nanoparticles were applied to the chitosan group with hemisection stie. From the first wee...

Lingang Dai1,2,3, Xiang Chen1,2,3, Jiajin Huang1,2,3, Jiali Xu1,2,3, Meimei Xiao1,2,3, Jiajing Chen1,2,3 and Yong Ruan1,2,3*

... white goat to obtain F3 generation of Boer × White goat hybrid to improve its production performance. To study the effect of PGAM2 gene polymorphisms on the performance of F3 generation hybrid goats, the relationship between PGAM2 gene polymorphisms and slaughter traits, meat quality traits and organ coefficients was determined in 39 F3 generation hybrid goats. The results showed th...
Nael Abutaha, Fahd A. AL-Mekhlafi*, Khalid Elfaki Ibrahim, 
Mohammed S. Al-Khalifa and Mohamed A. Wadaan
...d peritrophic membrane degeneration. The extract also showed high cytotoxic activity against HUV-EC cells, with an LC50 of 19.8 µg/mL. The results indicated that G. mangostana has larvicidal activity against Cx. pipiens larvae. Further investigation can be done to confirm the larvicidal potential of this plant against different genus and species of mosquitoes.

...

Salema Lafta Hassan1*, Taghred Jabbar Humadai1, Sabrin Ibraheem Mohsin

...es revealed testicular degeneration, together with the absence of spermatids, no epididymal sperm in the epididymal tubules. In conclusion, Folcord has a severe toxic effect on mice, as evidenced by histological and immunological changes in the male reproductive mice, according to the results of the current study.
 
Keywords | Spermatogenesis, Mice, Experimental design, Folcord, Oil adjuvant vaccine (OAV), Pasteurella multocida

Muhammad Nadeem1, Muhammad Naveed2,3*, Muhammad Shafiq2, Irfan Rasool2 and Muhammad Afzal Zahid2

...combinants in subsequent generations. Resultantly, a uniform and high yielding progeny line PCK-09012, later designated as “Noor-2019” was selected and evaluated for yield, agronomy, and insect pests. This cultivar revealed a potential yield of 2882 kg ha-1 in testing phase and outperformed standard checks by producing 78.2%, 13.1%, and 28.8% higher grain yield in station, adaptation and national uniform yield trials, respectively. The plants of No...

Qamer J. Jadoaa, Raffal A. Omar*

...5% Diclofenac, on bone regeneration. Forty-five adult male rabbits of the local breed were employed to create a 3.5mm hole defect in the proximal third of the medial aspect of the tibia by an electric drill with dropping isotonic normal saline to prevent thermal necrosis. The experimental animals were divided randomly into three equal groups, each group include fifteen rabbits (n=15). control without any additive. group 1(lidocaine hcl). Which applied daily si...

Tayfun Karatas1*, Betul Apaydın Yıldırım2 and Serkan Yıldırım3

...r, CMN exposure led to degeneration, steatosis, and necrosis in liver hepatocytes as well as hyperemia and inflammation in the liver and caused degeneration, desquamation, necrosis and adhesion in the gill epithelium. Additionally, expression levels of 8-hydroxy-2-deoxyguanosine (8-OHdG) and Caspase 3 were severe in the liver and gill tissues. However, both 50 and 100 mg doses of TLE had protective effects against CMN-induce...

Hongsen Xu*, Xiaoni Wang, Tie Tian, Changyu Zhao, Denghang Yu and Jun Liu

... changes, such as cell degeneration and necrosis, hemorrhage and inflammatory cell infiltration, were found in diseased crayfish. In conclusion, this study confirmed the pathogen of whitish muscle disease in farmed P. clarkii, and preliminarily investigated the biological characteristic, pathogenicity and drug sensitivity of this bacterium. The results of this study will provide scientific guidance for the effective prevention and control of muscle turbidity o...
Fen Wang1,2, Lin Zuo1,2, Xiang Zhou1,2, Zhu Chen1,2, Xiao Na Xu1,2, Suo Fei Ji1,2, Guan Jun Hou1,2, Cheng Jun Zhu2, Ye Zhang3, You Feng Su4, Gendong Jin5, Jia Jia Wang1,2, Yuan Gao6, Guang Tong Song1,2* and Ye Lin Jiang1,2*
...dy of two types of third-generation Chinese soft-shelled turtles (Trionyx sinensis) from the Yangtze River (i.e., Type A with black spots on the carapace and Type B without spots) was conducted to evaluate the effect of selective breeding on their nutritional composition. Our nutrient analysis results indicated that both types were high-quality aquatic products with high protein and low fat contents. The amino acid contents in the muscle of type A were signifi...

Ghaith Z. Hasan Al-Askari *, Eman H. Yousif Al-Taee

...stion, hemorrhage, and degeneration of hepatic cells. Some sections of the kidneys show vacuolation of mesangial cells in the glomerular tuft. Muscles of treated rats revealed severe histopathological changes under stress from both doses of toxic cholecalciferol, also showing the widespread mineralization of muscle fibers. From this study concluded that both doses of vitamin D can be toxic to organisms at higher levels, so they need to be used carefully and sh...

Nadya Indriyani1, Sri Murtini2*, Sri Darwati3, Cece Sumantri3

...mation were collected in generations 3 and 4. In the third generation, as many as 36 chickens (9 males and 27 females) aged 27 weeks and 162 IPB-D3 chicken eggs, in the fourth generation aged DOC and 2 weeks, each 81 samples. Total Immunoglobulin yolk (IgY) observations were made using Enzyme Linked Immunosorbent Assay (ELISA) and antibody titer against Newcastle disease virus (AbNDV) meth...

ADEEBA SYED1, DILAWAR HUSSAIN2, UZMA RAFI1 & SUMAIRA MAZHAR1*

...atrophy, shrinkage and degeneration of intestine was observed for different CPF concentrations. Kidney sections of Labeo rohita under different CPF concentrations exhibited nuclear hypertrophy, vacuolar degeneration of glomeruli, and occlusion of tubular lumen, cloudy swelling degeneration and hyaline droplets degeneration. In the liver tissue prominent ...

 Muhammad Sultan1,4, Muhammad H. Mahmood2,4, Takahiko Miyazaki3,4, Shigeru Koyama3,4, Zahid M. Khan1

 

...ccant/system size, and regeneration temperature etc. Usually it is difficult to measure open-cycle adsorption kinetics precisely in adsorption heat pump systems. Therefore, present study provides an experimental comparison of close and open cycle based water vapor adsorption kinetics for the development of desiccant air-conditioning system. In this regard, a polymer based hydrophilic sorbent was used for close and open cycle adsorption measurements. Gravimetri...

Nabaa Fadhil Abbas*, Raffal A. Omar

...ration of turnover and regeneration of epidermal cells to normal levels. The study concluded that tramadol and remifentanil with epinephrine impede burn wound healing in rabbits, highlighting the need for caution in their use.
 
Keywords | Lidocaine, Remifentanil, Tramadol, Wound healing, Rabbits, Adjuvants
...
Mouhamed Zakiou Kolawole Adissa Raimi1, Ghulam Hussain2, Nousheen Zafeer3, Faheem Ahmad1, Muhammad Irfan4, Anwar Ullah1, Imdad Kaleem1 and Asghar Shabbir1*

Marah Salim Hameed1, Ali Ibrahim Ali Al-Ezzy2*

... tubules with vacuolar degeneration surrounding proximal and distal convoluted tubules and tubule necrosis with dilation and vacuolar degeneration of proximal and distal convoluted tubules. Nitro blue tetrazolium activity for monocytes and macrophages do not correlate with blood urea and creatinine concentrations. Vitamin E -sodium selenite and vitamin C have important role in enhancement for renal functional activity and cl...

Hayder S. Rwayyih*, Tahani S.S. Al-Azawi

...myocardial endothelial degeneration and congested blood vessels. The aorta of these groups has enlargement and thickening of endothelial cells with infiltration of fatty cells in tunica intimae (The structure of intima changes in postmenopausal and it becomes multilayered due to migration of smooth muscle cells from the media to intima). In conclusions, the result of the current study could prove that Alpha lipoic acid has a protection on cardiovascular system...

Muhammad Ilyas Riaz1, Masood Rabbani1*, Sohail Raza1, Ali Raza Awan2, Aleena Kokab1, and Rida Haroon Durrani1

...superior immune response generation. The findings of this study revealed that the highly attenuated B. abortus ΔpurD mutant can be used effectively as a potential live attenuated vaccine candidate for the control of bovine brucellosis both in local and international settings.

...

Pakistan Journal of Zoology

April

Pakistan J. Zool., Vol. 56, Iss. 2, pp. 503-1000

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