Kathryne E. Taylor1 and Karen L. Mossman1,2*
Leonard Izzard1, 2, John Stambas1, 2*
...pulate pathogenicity and immunity and as biomarkers for disease severity....
Shen Yang1, Guang-Zhi Tong1, 2*
...stify;">Antiviral innate immunity plays a central role at the early stage of viral life cycles. The highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) is a major concern for the swine industry and causes high degrees of morbidity and mortality. The intracellular signalling cascades of the innate immune system triggered by HP-PRRSV often lead to the elimination of infection. However, HP-PRRSV induces pathological changes and can ca...
Oladipo Elijah Kolawole*, Oloke Julius Kola, Awoyelu Elukunbi Hilda, Olasunmibo Oluwatobi Gabriel, Ogunyale Tolulope Temitope
E-mail | koladipo2k3@ yahoo.co.uk
...us due to their impaired immunity. The study was carried out to determine the sero- prevalence of Hepatitis E among people living with Human Immunodeficiency Virus in Ogbomoso. The blood sample of consented two hundred and seventy five (275) subjects were obtained and their sera were screened for antibodies to HEV using Enzyme Linked Immunosorbent Assay. Samples were collected over a period of 4 months (September – December, 2014). The mean age and mean ...
John G. Bruno
...to provide rapid passive immunity for large human populations in the event of a major pandemic or infectious disease doomsday scenario. ...
Muhammad Abubakar1*, Shumaila Manzoor2, Jonas Johansson Wensman3, Emeli Torsson3, Qurban Ali1 and Muhammad Munir4
...lly mediating protective immunity, may explain the extreme infectious nature of the virus and its host-specific pathogenesis. Moreover, understanding the nature of such circulating field viruses is essential to underpin the endemic potential of PPRV and its possible spread to the susceptible wild or domestic small ruminants....
Iqra Mahmood1, Asif Nadeem1*, Masroor Ellahi Babar2, Muhammad Muddassir Ali1, Maryam Javed1, Aisha Siddiqa1, Tanveer Hussain2 and Muhammad Tariq Pervez2
...solution of mastitis and immunity related diseases.
...
Gabriela Mansano do Nascimento, Helena Lage Ferreira and Clarice Weis Arns
...inst the virus is innate immunity whose activation is independent of the antigen and depends on the ability of the host to recognize pathogens by means of specific pattern recognition receptors. This interaction induces the production of cytokines, chemokines and interferons. Through Janus kinase/signal transducers and transcription activators pathway, interferon induces the transcription of interferon-stimulated genes (ISGs), responsible for playing an essent...
Uzma Farid Durrani1,*,Sagar Mal Goyal2, Asim Khalid Mahmood1,Cathleen Hanlon3, Susan Moore3, Muhammad Waqas1 and Raheela Akhtar4
... lacking maternal rabies immunity. One basis of findings of this study it was concluded that puppies population lacking maternal rabies immunity is one of the responsible factors for increasing incidence of rabies in humans and dogs living in Lahore, Pakistan.
...
Mahmoud Said1*, Abd El Satar Arafa1, Mohammed A. Rohaim2* and Hussein A. Hussein2
...ence of maternal derived immunity impact of maternal derived immunity interference in vaccination regimen in poultry, a total of one hundred day old commercial broiler chicks were vaccinated with LaSota. A group of chicks (n=40) were immunized using baculovirus (H5 and ND) inactivated vaccine via subcutaneous route. Birds (n=20) were then either challenged with 106 EID50 using Egyptian avian influenza H5N1 and Newcastle dise...
Naila Chand1,*, Shabana Naz2, Hamza Maris1, Rifat Ullhah Khan1, Sarzamin Khan1 and Muhammad Subhan Qureshi1
...n growth performance and immunity in broilers under natural summer stress. A total of one hundred and twenty day-old broiler chicks were divided into four different treatment groups such as Bet-0, Bet-1.0, Bet-1.5, Bet-2.0 having betaine supplementation at the rate of 0, 1, 1.5 and 2 g/kg feed, respectively. Significantly (P<0.05) higher weekly and total feed intake and weight gain were recorded in group Bet-2.0. Higher level of betaine supplementation sign...
Yanjie Guo1, Weini Wu1, Hongmei Wang2, Xiao Guo2 and Yongping Xu2,*
...and the process of local immunity in the female reproductive system is regulated by the coordinated integration of the nervous, immune and endocrine systems. The nerves that branch from the inferior mesenteric ganglion (IMG) are a major source of sympathetic nerves, which dominate the immune response of the female reproductive system. Interleukin-18 (IL-18) is an important Th1 cytokine and plays an important role in pregnancy. To explore whether or not Th1 cyt...
Lotta Wahldén1, 3, Ulf Emanuelson1, Torsten Møller2 and Jonas Johansson Wensman1*
...ed to provide protective immunity in the African wild dog; however, their use has been hampered by the fear of vaccine-induced disease. Kolmården Wildlife Park in Sweden has used a live attenuated vaccine without any apparent cases of vaccine-induced disease, but no studies to evaluate immune response after vaccination have been performed. The objective of this study was to gain more knowledge about immune response following vaccination of the Afric...
Hazrat Nabi1, Irshad Hussain2, Muhammad Adil3, Amar Nasir3,*, Arbab Sikandar3, Saeed Khan1 and Nasrullah Khan3
...Plus 3.0) on the humoral immunity, lymphoid organs and growth performance of broilers. In this study, a total of 118 day-old broiler chicks were used, of which 108 were randomly divided into 6 groups (A to F) on day 14th. Aflatoxins derived from Aspergillus parasiticus were mixed in the feed measuring 150 ppb and fed to various broiler groups. Mycotoxin binders were also added into the feed and offered to group E and F from 14th-42...
G. Venkatesan* and Amit Kumar
...nd conferring short term immunity in contrast to other pox viruses and also produce localized skin lesions in humans who are in contact with infected animals and their products. Unique and specific virulence genes located at termini of ORFV genome with their encoded products are attributed to host immune evasion, short-term immunity both in natural infection post-vaccination in target species and repeated host susceptibility...
Muhammad Zahid1, Aneela ZameerDurrani1, Muhammad Ijaz1, KhushiMuhammad1,Muhammad Usman1,*, Muhammad Husnain1 and Nadeem Kamal2
...d 52.2% prevalence. When immunity status was taken into account it was found that vaccinated animals showed very low prevalence, i.e. 4.39% as compared to non-vaccinated animals having 66.53%. Another risk factor age suggested that younger animals were more affected (60.17%) as compared to older ones (29.41%). It was also observed that animals in closed housing system were more affected as compared to open housed animals. When comparative efficacy of di...
Jafar Aqeel Naqi1, Abdul Mateen1, Dilawar Hussain2,*, Hafiz Muhammad Tahir2, Sajjad Hussain1 and Abuzar Tabasum1
...at garlic can be used as immunity stimulant and to enhance growth performance in Nile tilapia.
...
Ali Raza Jahejo1,2, Nasir Rajput2, Wen-xia Tian1,*, Muhammad Naeem2, Dildar Hussain Kalhoro2, Asmatullah Kaka2, Sheng Niu1 and Fa-jie Jia1
...ize, feed efficiency and immunity of heat stressed broiler chicken.
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Jie Yang
...teins (PGRPs) are innate immunity proteins that are conserved from insects to mammals, recognize bacterial peptidoglycan, and function in antibacterial immunity and inflammation. Mammals have four PGRPs (PGLYRP1, PGLYRP2, PGLYRP3 and GLYRP4). They are secreted proteins expressed in different tissues. It is significant to make a study of human PGLYRP1 because neutrophils are a more dominant mechanism in human host defense. Re...
Sheng Niu1, Ali-Raza Jahejo1, Fa-jie Jia1, Xin Li1, Guan-bao Ning1, Ding Zhang1, Hai-li Ma1, Wei-fang Hao2, Wen-wei Gao1, Yu-jun Zhao1, Shi-min Gao1, Jian-hui Li1, Gui-lan Li1, Fang Yan1, Rong-kun Gao1, Huan-chun Chen1,3 and Wen-xia Tian1,*
...ctor molecules in innate immunity. In this study, thiram has been used to induce tibial dyschondroplasia (TD) and the chickens were injected with different doses of recombinant glutathione-S-transferase A3 (rGSTA3) proteins. We explored the responses of HDPs in erythrocytes to thiram-induced TD and rGSTA3 protein by quantitative real time PCR (qRT-PCR). The results showed many HDPs expressions were suppressed by thiram-induced TD, and the expressions of HDPs w...
Rana Waqas Arshad1, Asim Aslam1, Muhammad Saeed Imran1, Kamran Ashraf2 and Raheela Akhtar1,*
...itive impact in terms of immunity, histopathology of bursa of Fabricius and FCR. These results can be implemented in field for complete protection and better growth performance of broiler industry.
...
Nida Zia1, *, Ayesha Maqbool2, Muhammad Safdar3, Umm-I-Habiba1, Altaf Mehmood4, Muhammad Usman5, Zahid Iqbal6, Javed Iqbal6, Shahid Mehmood6, Amanullah Khan7 and Sajid Umar8
...rb growth, viability and immunity in commercial broilers. The main aim of the present study was to detect and characterize FAdVs. Liver tissues were collected from poultry flocks showing clinical signs of HHS and investigated using PCR assay for FAdVs. The FAdVs were detected in 8 samples collected from different flocks. Positive PCR amplicons were sequenced to genetically identify the FAdVs. Phylogenetic analysis revealed two distinct clusters among FAdVs. On...
Ali Mujtab Shah1,2,3, Muhammad Naeem2, Muhammad Giasuddin Shah2, Muhammad Haaroon2, Quanhui Peng1 and Zhisheng Wang1,*
... growth performance, and immunity of Holstein Friesian (HF) calves. The applied feeding methods were stomach tube (ST), nipple feeder (NF) and natural suckling (NS). A total of 15 newly born HF calves were selected randomly from the available stock and divided into 3 groups, each of 5 calves. The median birth weight (kg) ± S.D of calves fed by ST, NP and NS were recorded as 28.68±1.16, 28.44±0.67 and 28.56±1.13, respectively....
Huma Sattar1, Sehrish Firyal1,*, Ali Raza Awan1, Habib-Ur -Rehman2, Muhammad Sajid Hasni3 and Amjad Islam Aqib4*
... are directly related to immunity against mastitis might be helpful for animal selection trait and prevention of this disease. The aim of the present study was to assess the effect of polymorphism in bovine tumor necrosis factor alpha (TNF-α) gene on immune function and its role in mastitis susceptibility in Pakistani Sahiwal cows. In this study, a total of 150 Sahiwal cows were selected suffering from clinical (n=50), subclinical (n=50) mastitis ...
Mumtaz Ali Khan1,*, Sher Bahadar Khan2, Shakoor Ahmad2, Irshad Ahmad3, Ikramul Haq4, Kashif Prince1, Asad Ullah5, Muhammad Shoaib2, Shahid Zaman6, Amjad Islam Aqib7, Ghazunfar Rashid1, Mahboob Ali1, Imdad Ullah Khan4,Imad Khan5, Naimat Ullah4 and Muhammad Shahid8
...pplementation on humoral immunity against Clostridium perfringens type D epsilon toxin in goats to sort out better immunogenic approach. This study was conducted on total of 36 healthy animal of equal number of rabbits and goats. Each species was divided randomly into three equal (n=6) groups. Group A was supplemented vitamin E and group B was without vitamin E supplementation in both species. Animals of both groups were vaccinated with enterotoxaemia v...
Hanif Ullah1, Muhammad Inayat Ullah Khan2, Suleman3, Sawar Khan1,Salma Javed4, Abdul Qadeer1, Mohsin Nawaz1, Sardar Azhar Mehmood4
...and implicated with weak immunity whereas P. vivax was found the most common causative agent of malaria in District Dir Lower, which needs immediate attention to take preventive measures.
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Ali Mujtaba Shah1,2,3, Ali Raza Shah3, Muhammad Farooque Hassan2, Muhammad Yousif2, Zhisheng Wang1*
...strum to develop passive immunity. Regardless of placental structure and transfer of immunity in utero, ingestion of colostrum after birth also confers additional protection by binding to intestinal receptors which could otherwise be bound by bacteria. Moreover, the adequate colostrum reduces neonatal mortality, strengthen immunity and increase animal lifespan. Delaying intake of colostrum...
Huanxin Zhang1,2, Hongshuo Tang3, Jun Chen1, Yu Zang1,2, Xuexi Tang1,2,* and Ying Wang1,2,*
...ay to examine the innate immunity of this endangered carnivore. 10 TLR genes (TLR1-10) were initially identified from the African hunting dog and lesser panda. The results showed that most of the TLR genes were very conservative in the African hunting dog. We found 6 of ten TLR genes had the evidence of positive selection, only a small proportion of sites show evidence of selection, ranging from 0 to 9. In the present study, only four and three common positive...
Irfan Shahzad Sheikh, Masroor Ahmad Bajwa, Nadeem Rashid, Muhammad Zahid Mustafa, Mohammad Masood Tariq*, Majed Rafeeq, Abdul Samad, Tauseef M Asmat and Asad Ullah
...s performed to determine immunity against total sheep red blood cell (SRBC) , mercaptoethanol-2 resistant (IgG) and mercaptoethanol-2 sensitive (IgM) antibodies on weeks 3, 4, 5 and 6. Lymphoid organ weight showed non-significant difference (P>0.05), with numerically higher weight in immune modulator groups. The vitamin E supplemented group had highest HI antibody titers (7.22±0.25, 7.36±0.18 and 6.55±0.38). In experiments 1 and 2, supp...
Housh Muhammad Solangi1, Javaid Ali Gadahi1*, Mansoor Tariq2, Bachal Bhutto1, Zubair Ahmed Laghari1, Jamila Soomro3, Taufeeq Ahhmed Khosa1 and Abdullah G Arijo1
... are able to produce the immunity and can be used as vaccine against the infection. However the results of FECRT indicated that HcCP produced partial immunity against the infection.
... 
