Comparison of the Efficacy of Some Regimes of Vaccination for the Control of VVIBDV in Broilers
Comparison of the Efficacy of Some Regimes of Vaccination for the Control of VVIBDV in Broilers
Abd El-Razakl, A.G. and AboElkhair2, M.
ABSTRACT
Two vaccination programs for infectious viral disease (IBD) were compared in broiler chicken with maternal immunity, placed in tow farms, A and B. IBD immune complex vaccine was administered by subcutaneous route, at the hatchery into chicks of farm A at age of I day. On farm B, the attenuated intermediate plus live IBD vaccine was given via drinking water at the age of day. The vaccine uptake was monitored via serology, bursal indices and effect of the two vaccines on immune response to Newcastle disease and avian influenza vaccines. It was also verified by an experimental very virulent IBD challenge performed at the age of 2e day in birds transferred from the farms with appropriate control groups in a laboratory. The immune response on farm A showing higher serological titer at the age of 35 day via ELISA test. Both two vaccines provide complete protection against mortality but not protection against bursal atrophy or histopathological changes after challenge. As well as RT-PCR-based viral IBD detection in bursa of Fabricius at day post challenge.
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