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Maureen McKeague1, Maria C. DeRosa2*

...ity remains a challenge, leading to the recent emergence of elegant new approaches and tools for SELEX. In this commentary, we discuss recent advancements in the selection of aptamers.

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Ethan G. Quillen

...has grown in popularity, leading to both positive and negative results. On one end, this has engendered a polyvocal and polyfocal discourse, garnering perspectives from a number of different methodological and theoretical approaches so as to develop a truly inter- and multi-disciplinary understanding about what we mean when we discuss Atheism. On the other, this myriad of voices has equally led to an ever-broadening discordancy, an equivocal discourse that mak...

Oladipo Elijah Kolawole*, Oloke Julius Kola, Awoyelu Elukunbi Hilda, Olasunmibo Oluwatobi Gabriel, Ogunyale Tolulope Temitope

E-mail | koladipo2k3@ yahoo.co.uk

...ised individuals usually leading to liver cirrhosis. Individuals living with Human Immunodeficiency Virus have a greater risk to the virus due to their impaired immunity. The study was carried out to determine the sero- prevalence of Hepatitis E among people living with Human Immunodeficiency Virus in Ogbomoso. The blood sample of consented two hundred and seventy five (275) subjects were obtained and their sera were screened for antibodies to HEV using Enzyme...

Muhammad Zubair, Sajid Mahmood Sajid

...gonadotropin release and leading to up-regulation of ovulation. It has useful effects on the reproduction of female in terms of reduction in puberty and ovulation induction. The beneficial effects are manifested in male in terms of improvement of semen.

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Ummara Waheed Khan, Raza Ahmed, Irum Shahzadi and Mohmmad Maroof Shah

Email | mmshah@ciit.net.pk

...reeding has been on leading edge. The discovery of molecular genetics and biotechnological techniques, such as genome mapping, tissue culture, genetic transformation and in vitro regeneration offered new dimensions of research to improve important crop species including wheat. The tissue culture by itself has increased the crop improvement potential to develop new cultivars with desirable traits through somaclonal and gametoclonal sele...

Shahid Ali1, Habib Akbar2, Mohammad Tariq Jan2, Mohammad Jamal Khan3 and Abdul Bari4

...ence, visible crop stand leading to yield and yield components. Significant differences were observed among cane portions and setts placement methods for all the traits except emergence %. Planting sources exhibited significant differences for emergence percentage. The interaction of cane portions and setts placement methods were significant except for emergence percentage. Millable canes showed significant interaction for planting sources and setts placement ...

 Mukhtiar Ahmed, Jana Pickova, Taufiq Ahmad, Muhammad Liaquat, Abid Farid, Muhammad Jahangir

...among food constituents, leading to both desirable and undesirable products. Food lipids are the foods components that are most susceptible to oxidation, therefore oxidation reactions are one of the major sources of deterioration that occurs during manufacturing, storage, distribution and final preparation of foods. Lipid oxidation products are omnipresent in foods, although much variation exists in their kind and levels present. Although levels of these compo...

John G. Bruno

...aration in food samples, leading to a greater ability to detect these serotypes if coupled with genetic identification techniques such as PCR or gene probe hybridization.

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Iram Liaqat1*, Najma Arshad2, Muhammad Arshad3, Safdar Ali Mirza4, Nazish Mazhar Ali1 and Ammara Shoukat1

...tance is emerging, hence leading to serious health issues. Among 24 strains isolated from Shaukat Banaspati Ghee industry (Grw) and Shezan foods (pvt) Ltd, Lahore, Pakistan food industry, 10 highly antibiotic resistant strains were subjected to morphological, physiological and biochemical characterization. 16SrRNA sequencing was performed to identify three highly resistant strains at species level. Antimicrobial activity of aqueous and methanolic plant extract...

Fida Mohammad, O.S. Abdalla, Sheraz Ahmed, Fakharuddin and S. Rajaram

...Hadya and Breda i.e. the leading research venues of International Center for Agricultural Research in the Dry Areas (ICARDA), Syria. The experimental material comprised of forty synthetic derived wheat lines along with eight check cultivars was planted in alpha lattice design with three replications. Genotypes exhibited significant (p≤0.01) variations for all the studied traits excluding biomass. Genotype by environment interactions (GEI) were significant f...
Amjad Islam Aqib1, Muhammad Ijaz1,*, Aneela Zameer Durrani1, Aftab Ahmad Anjum2, Riaz Hussain3, Saba Sana2, Shahid Hussain Farooqi1, Kashif Hussain1 and Syed Saleem Ahmad1
...ound 52.5% (63/120) with leading subclinical (41.67%, 50/120) form of mastitis on overall milk collected data. Pathogen type was crowned by Staph. aureus with 74.5% (47/63) prevalence, following which were Streptococcus species (17.45%, 11/63), E. coli (3.17%, 2/63), and Bacillus cereus (4.76%, 3/63). Coagulase positive Staph. aureus (41 out of 47), and hemolysin producing Staph. aureus (39 out of 47) primed among S...
Muhammad Tahirand Memoona Shehzadi*
... of chemical fertilizer, leading towards the sustainable agriculture.
...
A. Hamid1,*, M. Ilyas2 and S. Kalsoom3
...fy;">Hypercholestrolemia leading to cardiovascular diseases are very common problem in Pakistan and in most cases it is caused due to insufficient intake of dietary fiber.A study was conducted to evaluate the role of dietary fiber and ß-glucan from major food grains used locally on plasma cholesterol level of dietary-induced hypercholesterolemic rats. Insoluble dietary fiber (lignin and cellulose) was extracted from wheat and maize, while ß glucan ...
Mehran Kausar1,2, Naveed Ashraf3, Farzana Hayat4, Asraf Hussain Hashmi1, Saima Siddiqi1,* and Mariam Anees2
... resorption consequently leading to short stature, increased bone density, recurrent fractures, stubby hands and feet with dystrophic nails, unossified fontanels, and an obtuse mandibular. The present study was conducted to determine the underlying genetic cause of Pycnodysostosis in a family from Azad Kashmir, Pakistan presenting with symptoms of multiple recurrent fractures, short stature, increased bone density and stubby hands. We performed direct sequenci...
Usman Waheed1,*, Humayoon Shafique Satti2, Muhammad Arshad3, Ahmed Farooq3, Abdul Rauf4 and Hasan Abbas Zaheer1,5
...roups (HRGs) in Pakistan leading it away from achieving the 6th millennium development goal of halting and reversing HIV/AIDS epidemic. Syphilis increases the risk of HIV transmission by two to five times, and this co-infection is common among HRGs. The objective of this study was to investigate the prevalence of HIV/AIDS and syphilis among selected HRGs. During a period from September 2015 to February 2016, community-based sampling was done from 13...

Fawad Ali1*, Hidayat Ullah2, Ikhtiar Khan1

... effect on soil quality, leading to food contamination. The extractable concentration of metals viz Pb, Cr, Cd and Zn through ammonium bicarbonate diethylenetriaminpenta acetic acid (AB-DTPA) showed significant differences between the two studied localities. Linear regression analysis indicates that concentration of the heavy metal (Pb, Cr, Cd, Ni, Zn) in vegetables are significantly correlated at R2 value of 0.956 at P≤0.001 with their extractable concentr...

Mohsan Ullah Goraya1,2, Liaqat Ali1,2 and Iqra Younis3  

... cytokine and chemokines leading to establishment of an antiviral state of the host. In this review, we discuss the recent understanding in host responses to avian viral infection and their impact in health and disease. 

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Malak Atiq Ullah Khan* and Fida Mohammad 

...-1) and thus appeared as leading genotype for yield and production traits. Similarly, G-79 had higher grain yield in all test environments except E-03 i.e. E-01 (4537 kg ha-1); E-02 (4840 kg ha-1); E-04 (5035 kg ha-1); E-05 (4976 kg ha-1); E-06 (4797 kg ha-1); E-07 (5024 kg ha-1); E-08 (4767 kg ha-1); E-09 (4886 kg ha-1) signifying it as high yielding and widely adaptable genotype. However, G-08 with higher grain yield in E-01 (5272 kg ha-1) and E-07 (4840 kg ...

Rahila Nizami1, Muhammad Zahid Latif2*, Intzar Hussain3 and Khalid Rashid

...y of scenarios including leading wards, camps, campaigns, open houses, seminars and symposiums as well as day-to-day bases dealing with clinical directors and managers. This research was conducted to study the leadership styles among the medical professionals. For this purpose, a cross sectional and non-probability convenient sampling was conducted involving 59 medical professionals of Azra Naheed Medical College, Lahore. The assessment of leadership-style (T-...

Abida Sajid* and Aqsam Sajid 

...fall in hemoglobin level leading to anemia and adverse pregnancy outcome especially in young girls. Anemia is a major public health problem. Around 58.27 million women worldwide are anemic during pregnancy 95% of whom live in countries that are developing. To know the frequency of anemia, and obstetric outcome in terms of preterm delivery, low birth weight and rate of caesarean section in young Primigravida. It was a cross sectional study, conducted in the dep...

Imtiaz Hussain*, Hassnain Shah, M. Azeem Khan, Waqar Akhtar**, Abdul Majid*** and M. Yaqub Mujahid*

Corresponding author:izhussain@yahoo.com

PRODUCTIVITY IN RICE-WHEAT CROP ROTATION OF PUNJAB: AN APPLICATION OF TYPICAL FARM METHODOLOGY
...ease and insect invasion leading to yield losses. Berseem is the only crop that breaks this rotation. Farmers are aware of the beneficial effects of this crop rotation and believed that this riceberseem rotation control weeds in the next wheat crop along with yield -1 -1 improvement of both rice (upto 5.4 md acre ) and wheat (4.4 md acre ). However there is need to assess the economic impact and evaluation of berseem in rice-wheat cropping system and evaluatio...

 Muhammad Tariq*, Raja Muhammad Omer**, Muhammad Ashraf Mian*, Obaid Ur Rehman***, Amjad Tahir Virk and Kazim Abbass**

PROMOTING CERTIFIED SEED AVAILABILITY OF WHEAT (TRITICUM AESTIVUM L) THROUGH PUBLIC-PRIVATE PARTNERSHIP AND ITS IMPACT ON YIELD IN RAINFED AREAS
...lesser vegetative growth leading to poor crop yield. Hence, it is the need of the time to enhance provision of certified seed of improved varieties to the farmers. An approved wheat variety 'Chakwal-50' of rainfed areas was selected for certified seed production and distribution in rainfed District Chakwal under joint venture of a study on comparison of seed source(Certified vs. Farmer's seed) contribution towards wheat yield at six sites in the District. All ...
Waqar Islam*
...use huge economic losses leading towards the famine. To cope with this situation, understanding plant disease triangle and disease epidemic forecasting is very important. So here we have briefly introduced plant disease epidemiology through highlighting its various types by giving important examples. We further have explained the plant disease triangle and disease forecasting systems via inclusion of various models being utilized worldwide.  
...
Nazish Imran 
... suicide being the third leading cause of death among adolescents.(1), (3) Child & adolescent mental health thus needs to be considered & emphasized as an integral component of overall health & growth of young population. Youth with positive mental health have positive self-efficacy beliefs, are productive and able to tackle developmental challenges adequately.(4...

Saleem Ashraf1*, Ashiq Hussain Sangi1Zakaria Yousaf Hassan3 and Muhammad Luqman2

...ecline. As the Punjab is leading contributor in terms of cotton production, this decline will impact economy and livelihoods significantly. Therefore, study urge the need of cotton policy and holistic actions by government to subsidize inputs availability and conserve water and land. 

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Usman Shakoor1, Ali Nasir2, Mudassar Rashid1, Muhammad Iftikhar-ul-Husnain1, Nabila Khurshid1 and Zuhair Husnain

... farmers increase income leading to higher income tax revenue. 

...
Muhammad Shaheer1*, Asad Aslam Khan2, Nasir Ahmed3, Tehseen Mahmood Mahju4, Ummarah Rasheed5
...ular edema is one of the leading causes of visual loss in diabetic patients. However, the impact of medicinal treatment on the occurrence of macular edema remained elusive.
Objectives: This study was designed to determine the effect of intravitreal bevacizumab in patients of diabetic macular edema.
Methods: An interventional study was conducted on patients that underwent pre-injection and one-month post-injection OCT for R...
Muhammad Younus1*, Sabah Usman2 and Samia Jawed3
...nuously. It is the fifth leading cause of death worldwide and is associated with decreased lung functions.
Objective: This study was designed to compare the pulmonary functions in obese and non-obese subjects. Additionally, we aimed to correlate the body mass index (BMI), waist circumference (WC), and waist-to-hip ratio (WHR) with pulmonary function tests (PFT’s).
Material and Methods: This cross sectional comparative study...

Zulqarnain and Zafar Iqbal* 

...al infectious strategies leading to the complete death of plant. None of the strategies in controlling the wilt have shown fruitful results. Dual culture assay was employed is this study to identify the fungal species with their potent antifungal activity against the Fusarium wilt of tomato. Six distinct fungal species including Penicillium sp., Aspergillus niger, Aspergillus flavus, Trichoderma harzianum, Alternaria solani and Pythium aphanidermatum showed gr...

Faheem Ali1*, Muhammad Naeem Arbab1, Abdul Basit2, Muhammad Kashif Khan1, Gulzar Ahmad1 and Muhammad Amir

...ed by the same number of leading VARs in order to ensure unity power factor, thus avoiding penalties on agricultural industry. Switched Capacitors and Voltage Regulators are used to cope with such a situation. Regulators results in higher line currents thus resulting in excessive losses in addition to voltage sag problems. On the other hand, static capacitors can tackle the reactive VARs, but in steps only. Thus, a real time solution is required for sensing, c...

Saman Fatima* and Shazia Iram 

...attack the healthy fruit leading to various infections or they can enter through various lesions caused by physical stress and worsen the condition. 

...
Zhen-li Li1,2, Hui-fang Zhou2,*, Bo-ru Zhou2, Bei Liu2, Xiao-fei Jiang2 and Jian-ya Xu2

 

...iscontinuation, possibly leading to luteal phase defect (LPD) and infertility. Recent studies revealed that mifepristone not only affects the ovary and uterus, but also the pituitary, resulting in LPD. Bu Shen Zhu Yun formula (BSZYF) was developed by Professor Guicheng Xia, a “great master in TCM.” It effectively cures LPD, while its effect on the pituitary is unclear. In this study, we aimed to explore the effect of BSZYF on gonadotropins and gona...

Syed Atif Hasan Naqvi1*, Sidra Mushtaq1, Muhammad Tariq Malik2, Ummad-ud-Din Umar1, Ateeq ur Rehman1, Shoaib Fareed3, Muhammad Asif Zulfiqar

Saleha Gul1,2, Muhammad Khisroon2, Ajmal Khan2, Attaullah1, Saira Gul3 and Gul Nabi Khan1,4,*
...ction of DNA adducts and leading to lung cancer. However, the adverse effects of cigarette smoke on other tissues are largely unknown. We explored the genotoxic effects of tobacco smoke on peripheral lymphocytes of active and passive smokers. Blood samples were isolated from 100 males’ including 25 active-, 25 passive- and 50 non-smokers. Alkaline comet assay was done and classes were defined on the basis of comet tail length. Significant differences wer...
Fazal Abbas1, Muhammad Ijaz1,*, Zunaira Akhtar1, Khalid Mehmood2, Muhammad Zeeshan Hyder3 and Umair Iqbal4
...p>...
Ghulam Murtaza1*, Razia Sultana2, Muhammad Arshad Malik3, Sibtain Afzal4, Mubashar Hussain5, Shahid Bashir6
...ne smoking is one of the leading causes of preventable diseases and premature death worldwide. Nicotine is a highly addictive substance, which exerts influence over different reward pathways of the brain. In Pakistan, nicotine use is very high and its consumption is expected to increase further in future. This article focuses on the increase of nicotine consumption in Pakistan and how people can get rid of smoking habit using the latest method such as transcra...
Asghar Khan1,*, Aneela Zameer Durrani1, Arfan Yousaf2, Jawaria Ali Khan1, Mamoona Chaudhry1, Mumtaz Ali Khan3, Habibunnabi4 and Amjad Khan5
...mastitis considered as a leading hindrance in the development of dairy industry in Pakistan. Pakistan is the top listed country with the highest prevalence of Sub-clinical mastitis. Therefore, this study was conducted to estimate the prevalence and assess the potential risk factors of sub-clinical mastitis in lactating buffaloes in Pothohar region of Pakistan. A questionnaire based cross-sectional based survey was conducted in 30 commercial and subsistent farm...
Rabia Khalid1, Saleema Bashir Shams1, Bibi Nazia Murtaza1,*, Gaitee Joshua1, Saira Mushtaq1, Hassan Al-Talhi2 and Abdulaziz Al-Amri2
... at higher risk for MetS leading to CVD, diabetes type-II, atherosclerosis and hypertension.
...
Zil-e-Huma1, 2, Abdul Malik Tareen3, Kaleem Ullah3, Tauseef M Asmat4,Abdul Samad4Asim Iqbal2, Mohammad Zahid Mustafa3*,Irshad Ahmad5 and Sadeeq ur Rahman6
...v>Diarrhea is one of the leading public health problems in under developed countries. In Pakistan, diarrheal cases are treated empirically and, rarely, specific investigations are made. This study was designed to identify the prevalent strains of Escherichia coli among children of less than five years of age in Quetta, Balochistan, Pakistan. A total of 200 samples were collected from children suffering with diarrhea. E. coli was isolated using st...
Fizza Anwar1, Muddassar Zafar1*, Zahid Anwar1, Raja Tahir Mehmood2
...e/threonine phosphatases leading to hindrance in bacterial growth. In addition, phylogenetic tree was also constructed using 18s rRNA gene of A. niger and gene clusters of secondary metabolites were determined through bioinformatics tools. 
...
Hafiza Sadaf Zahra1, Asia Iqbal2, Sayyeda Hira Hassan1, Hafiz Abdullah Shakir1*, Muhammad Khan1*, Muhammad Irfan3, Chaman Ara1, Shaukat Ali4
...d closing, respectively; leading to transcriptional activation and inactivation of genes. Histone acetylation has been frequently detected in oncogenes while histone deacetylation in TSG. Collective data from various studies demonstrate that DNA hypermethylation and histone deacetylation of TSG lead to inactivation of TSG and activation of oncogenes. The purpose of this review is to discuss the evidence based relationship between ALAN and oncogenes expression ...

Kalpana Polisetty1* and Kiran Kumar Paidipati2 

...s years but it holds the leading position in wheat production still in the country. 

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Nahed H. Ghoneim, Maha A. Sabry, Zeinab S. Ahmed and Esraa A. Elshafiee*
...onotic bacterium and the leading cause of human gastroenteritis worldwide. To investigate the occurrence and antimicrobial resistance of this pathogen, a total of 360 chicken cloacal swabs and 15 water samples were gathered from different localities in Giza and Cairo Governorates. An additional 50 stool specimens were collected from individuals in contact with the examined chickens. Eleven Campylobacter isolates were recovered through bacteriological ex...

Malak Atiq Ullah Khan1*, Fida Mohammad2, Fahim Ullah Khan3, Sheraz Ahmad2, Mian Ahmad Raza1 and Tariq Kamal

...anbaz), G-52 and G-79 as leading wheat genotypes based on grain yield. Spearman’s rank correlation revealed significant positive correlations of AMMI stability value (ASV) with CV, σi2 with Wi, and Wi with CV indicating that these parameters could invariably be used for identifying stable wheat genotypes depending upon the nature of the experiment, breeding material, and the complexity of data. Different stability models identified G-79 as high yie...

Amit Sharma1* and Pankaj Sood2 

...amage to the spermatozoa leading to reduced motility, viability, impaired transport and fertility. Caprine sperms are extremely sensitive to cryopreservation compared to other species which is mainly attributed to the compositional variation of the sperm plasma membrane. Different factors affect affects the semen cryopreservation viz. species, breed, semen collection technique, collection season, extender composition, type of cryoprotectant used, cooling rate...

Arjumand Nizami1, Muhammad Zulfiqar2*, Jawad Ali1, Naushad Khan2 and Imran Sheikh

...chnologies and practices leading to water productivity enhancement to address increasing irrigation water demand and declining water resources. One of such technology known as laser land leveling was introduced in Pakistan in 1980s. More recent introduction is of another water efficient technique known as The Alternate Wetting and Drying (AWD) technology evolved by International Rice Research Institute (IRRI). AWD intervention in conjunction with laser land le...

Muhammad Zeeshan Nazar*, Ayyan Umer, Zahid Mahmood Sarwar, Faiz Ullah Faiz and Sikandar Hussain 

...emolymph liquid impelled leading to mortality. Provide the required temperature and humidity with appropriate hygienic condition to B. mori are advised to produce healthy silk. 

...

Ejaz Ashraf1*, Anam Sarwar2, Muhammad Junaid1, Mirza B. Baig3, Hafiz Khurram Shurjeel4 and R. Kirby Barrick

...the most conspicuous and leading threat to the global agricultural system, particularly for developing countries. Pre-service and in-service training becomes extremely important for Extension Field Staff (EFS) to develop skills and abilities to assist them in identifying and addressing the impacts and challenges of climate change. This study was designed to utilize the Borich Needs Assessment Model for assessing the existing competencies and the training needs...

Ghulam Akbar1*, Muhammad Anjum Zia1, Ali Ahmad2, Neha Arooj1 and Shahneela Nusrat

...ascular diseases are the leading cause of death along the world about 30% of all deaths occur due to cardiovascular diseases. Among fibrinolytic enzymes streptokinase (SK) is commonly used in the world to cure heart diseases because its low cost and efficacy. It’s a microbial origin enzyme produced especially by Streptococcus bacterial spp. Therefore, it is antigenic in nature due to microbial source which restricts its use. However, it is necessary to t...
Sana Khan1, Raheela Taj1, Noor Rehman2, Asad Ullah3, Imad Khan3 and Sadeeq ur Rahman3,*
...of nosocomial infections leading to diarrhea, urinary tract infection and meningitis, is increasingly becoming multidrug resistant. The current study was aimed to determine the prevalence and antibiotic susceptibility pattern of extended spectrum β-lactamases producing C. freundii clinical isolates. A total of 2950 clinical samples were collected from both hospitalized and non-hospitalized patients of Khyber Teaching Hospital (KTH), Peshawar...
Dil Afroza Khanom1, Amirun Nesa1, Muhammad Abu Sayed Jewel1, Muhammad Ayenuddin Haque1, Alok Kumar Paul1, Sonia Iqbal2, Usman Atique2,3*, Lubna Alam4
...to heavy metals toxicity leading to mental retardation, kidney tissue damages, cancerous cell growth, and even death in case of chronic exposure. 
 

Mujahid Khan1*, Mohammad Tufail2, Muhammad Fahad1, Hazi Muhammad Azmathullah3, Muhammad Sagheer Aslam1, Fayaz Ahmad Khan4, Asif Khan5 

EXPERIMENTAL ANALYSIS OF BRIDGE PIER SCOUR PATTERN
...uring effects ultimately leading to severe pier damages. In
this research study, experimental investigation is carried out to find the scouring patterns in terms of scour depth
and its extent in lateral direction for circular and square pier models. For this purpose a number of experiments
were conducted in the physical modeling laboratory of River Engineering and drainage control, USM, Malaysia.
The study shows that the pier scour ...

Aqeel Nawaz1, Muhammad Ali Kamran1 

PARAMETRIC SENSITIVITY ANALYSIS OF CONVEX STAR PORT PROPELLANT GRAIN FOR SOLID ROCKET MOTOR
...reasing angular fraction leading to reduced tail-off. Thus neutrality and reduced tail-off cannot
be achieved simultaneously and trade-off has to be made. However, higher value of characteristic exhaust velocity
(C*) will reduce tail-off. 

...
Khizar AzamÙ­, Abdul ShakoorÙ­, Riaz Akbar ShahÙ­, Afzal KhanÙ­, Shaukat Ali ShahÙ­,
Muhammad Shahid Khalil٭٭
COMPARISON OF FATIGUE RELATED ROAD TRAFFIC CRASHES ON THE NATIONAL HIGHWAYS AND MOTORWAYS IN PAKISTAN
...er Fatigue is one of the leading causes of Road Traffic Crashes (RTC) in Pakistan . An attempt has been made in this research to compare the proportion of driver fatigue related RTC on the Motorways and National Highways of Pakistan. Data were collected from the National Highways and Motorway Police (NHMP). Data for 2003 to 2012 of all RTC on Motorways and 2003-2011 on the National Highways (N-5) were examined extensively by applying Australian Transportation ...

 Riaz Sayed1, Khizar Azam1, Waqar Shah1, Inayat Babar1, Hamidullah1, and Sahar Noor1

A REVIEW OF DRIVING UNDER THE INFLUENCE OF FATIGUE
...drowsiness is one of the leading causes of accidents throughout the world. The United States Department of Transportation (USDOT) estimates that every year driver fatigue causes close to 100,000 crashes in the United States. These accidents results in1,544 fatalities, 71,000 injuries, and $12.5 billion in monetary losses in the US alone. Around the world, thousands of lives are lost each day due to road accidents. The National Road Safety S...

 Usman Ali Naeem*, Hashim Nisar*, Habib-ur-Rehman** and Naeem Ejaz*

DEVELOPMENT OF FLOOD DISCHARGE MODELS USING GIS
...d better decision making leading to fructifying outcome. Physical hydrologic models for drainage areas are significant utensils to hold water assets management and foresee diverse hydrologic contacts and risks. Indus River is considered as salvation of Pakistan and it is also the largest river of the country. The approximate length of the river is 3180 kilometers and its drainage area exceeds 1165000 km2. Having in view the worth of Indus R...

Kamran Ghasemi1*, Mostafa Emadi2, Asghar Bagheri3 and Mehdi Mohammadi1

Casing Material and Thickness Effects on the Yield and Nutrient Concentration of Agaricus bisporus
...m production potentially leading to the variation in yields and nutritional characteristics of mushroom. Four casing layers comprising commercial casing soil (CCS), spent compost (SC), coco peat (CP) and vermicompost in three thicknesses (2, 4 and 6 cm) were evaluated in this study for production of Agaricus bisporus. The CCS treatment had the most mushroom yield (27.03 Kg m-2) whereas CP casing layer showed the minimum yield (4.43 Kg m-2). ...
Taqiur Rahman1, Tabassum Yaseen1*, Ali Mujtaba Shah2, Samiullah3, Ghulam Jelani3, Gul Nawaz1,Qudratullah Kalwar2
...study is to identify the leading medicinal plants used by local communities for the treatment of animals and document the threatened herbal knowledge from the elder formers (R1, R2 and R4) this study labels the ethno veterinary practices in different villages of District Shangla, where the documentation process is carried out through semi-structured questionnaires in 2017 (R1) where about seventy plant species belonging to different families of spermatophytes ...
Mumtazur Rahman1, Farhan Anwar Khan1,*,Umar Sadique1, Ijaz Ahmad1, Shakoor Ahmad1, Faisal Ahmad1,2, Hayatullah Khan1,3, Muhammad Saeed1, Faiz Ur Rehman1, Ibrar Hussain1, M. Faraz Khan1, M. Izhar ul Haque1 and Hanif-ur-Rehman1,3

...ly using and resultantly leading to antimicrobial resistance (AMR) including mycoplasmas, which are causing serious infections in ruminants. Since the growth curve of our local strain and its susceptibility to commonly using antimicrobials is unknown. Therefore, this study was aimed to evaluate the growth curve and susceptibility of Mccp against commercially available quinolones in Pakistan by broth microdilution method. Quinolones including moxifloxacin, levo...

Md. Gulam Rabbany Rassel1, Kazi Afsana Homayra Orchy1, Md. Moshiur Rahman Khan1, Marzia Rahman2 and Md. Mahmudul Alam1*

Hematological and Serum Biochemical Indices in Calves with Navel Ill
... to healthy calves. Some leading enzymes such as ALT, AST, ALP, LDH, CK were elevated in affected calves than their healthy counterparts. Creatinine, BUN, LDL, HDL, cholesterol and triglyceride were also elevated remarkably. Mild alterations of electrolytes such as Na+, K+, Cl- and Ca+2 were also observed. The results demonstrated that navel ill may compromise vital organs which should be promptly treated once diagnosed. To prevent infection, navel area should...

Amjed Ali1, Rafi Qamar1*, Muhammad Ehsan Safdar1, Salman Saleem2, Sami Ullah3, Muhammad Arshad Javed4 and Syed Wasim Hasan5

Development and Growth: Influence of Sowing Dates on Performance of Cotton Cultivars
...ing crop planting is the leading hindrance in its production. Therefore, this one-year field experiment was performed to assess the result of varying cultivars and sowing dates on developmental and allometric traits of cotton (Gossypium hirsutum L.) under the agro-ecological conditions at Sargodha, Punjab, during Kharif season, 2015. The study consisted of i) three cultivars viz. Bt. FH-142, Bt. MNH-886 and FDH-170 and ii) three sowing dates viz. 21st April, 5...

Salim Raza1*, Khan Gul Jadoon2, Sajjad Hussain1, Zahid ur Rehman1, Saira Sherin1 and Noor Muhammad1

Mitigation Plan for Identified Problems Faced by the Marble Industry in Khyber Pakhtunkhwa

Zarqa Khalid1*, Muhammad Asad ur Rehman Naseer1, Raza Ullah1 and Shahzad Khan2

Measuring the Global Trade Competitiveness of Pakistan’s Cotton Crop
...for the world’s 10 leading cotton exporters using revealed comparative advantage indices and relative competitive advantage indices such as Revealed Comparative Advantage (RCA), Revealed Symmetric Comparative Advantage (RSCA), Relative Import Advantage (RMA), Relative Export Advantage (RXA) and Relative Trade Advantage (RTA). The data were taken from the International Trade Center (ITC) UN-COMTRADE Statistics of cotton export and import from 2009-18. The...
Ashara Sajid1, Muhammad Usman Ghazanfar1, Saeed Rauf 2, Zahoor Hussain3, Salman Ahmad1 and Yasir Iftikhar1,*
...ng disease is one of the leading causes of the citrus decline in many parts of the world, including Pakistan. Adequate information about disease incidence is essential for the eradication and controlling measures of disease. In this context, a survey regarding the incidence of citrus green disease (CGD) was recorded in two cultivars Kinnow (Citrus reticulate Blanco) and Mosambi (Citrus sinensis (L.) Osbeck), among s...
Abdul Hafeez1*, Akhtar Nawaz Khan2 and Zahid Ullah3
... Furthermore, the phases leading to useful decision-making often follows pre- and post-processing in a subjective manner, which is tedious, time-consuming and erroneous. An important and an unrealized need of these systems is the real-time answer from the acquired data, which is often multi-dimensional and at remarkably high-resolution. The inherit noise in the data is another major bottleneck for real-time processing. This entails expediting the decision-maki...
Amjad Ali, Kafeel Ahmad*and Shaista Rahat
...unistic pathogen and the leading cause of nosocomial infection worldwide. This bacterium produces enzymes known as extended spectrum β-lactamases which render broad spectrum cephalosporins and penicillins inactive. This study reports antibiotic susceptibility pattern, multiple antibiotic resistance (MAR) index and prevalence of extended spectrum β-lactamases among clinical isolates of P. aeruginosa collected from tertiary care hospitals of Pes...
Waseem Khalid1, Ali Ikram1*, Muhammad Rehan2, Farukh Adeem Afzal1, Saadia Ambreen1, Marryam Ahmad3, Afifa Aziz1 and Anam Sadiq1
...ovative functional foods leading to a healthy food chain. It is concluded that the presence of bioactive compounds is fully justified by melon seed, including anti-inflammatory agents, hypoglycemic agent, antimicrobial, anti-genic and antioxidant potential.
...

 Muhammad Ajmal1, Saima Mustafa1, Fizza Ibrahim Bajwa1, Cheng Zhou2, Guangdong Wen2, Soe Lwin Myint2, Syed Irfan Raza3, Ihtasham Bukhari4, Mubashir Hassan5, Muhammad Faisal6 and Furhan Iqbal1*

...sine causing frame shift leading to premature termiation of the protein after 23 amino acid residues (p.P144LfsX23), resulting in a truncated HR protein with 166 amino acid residues. The mutation followed Mendalian pattern of inheritance as all the patients are homozygous for the mutation while parents were heterozygous and unaffected siblings from both families were either heterozygous for the reported mutations or they lacked this mutation.
...
Umair Riaz1*, Shazia Iqbal2, Muhammad Irfan Sohail2, Tayyaba Samreen2, Muhammad Ashraf1, Fatima Akmal2, Ayesha Siddiqui3, Ijaz Ahmad4, Muhammad Naveed5, Naveed Iqbal Khan5 and Rao Masood Akhter6
...pectively. Following the leading role of China with 1.48% share in MAPs exports, India is second largest exporter of MAPS with 8.75% share in Asian trade of MAPs. Various biomass and leftover produced with these plants production, as the MAPs cultivation withstands a huge economic potential, but it has several limitations to adaptation as arable crops i.e. lower prices, non-availability of transit markets, underdeveloped cultivation technology, poor availabili...
Canan Vejselova Sezer*
...ed countries. Two of the leading causes of the death of cancer are lung and breast cancers among males and females, respectively. A variety of drugs are in use for cancer treatment but their recruiting properties are limited because of the developing resistance and/or finiteness of bioavailability. Current research is aimed at synthesis of a new effective agent of a different type, silymarin-loaded solid lipid nanoparticles and investigation of its effectivene...

Aioub Sofizadeh1, Ehsan Allah Kalteh2, Shahin Saeedi3, Mulood Mohammadi Bavani4*

...nd was recognized as the leading cause of scorpion sting in the region. O. farzanpayi and M. caucasicus are new to the scorpion’s species of this province. M. eupeus is the most prevalent species in Golestan Province and is one of the dangerous the scorpion in the region. 

 
Novelty Statement | For the first time, we determined the distribution of scorpion species in Golestan province, also O. ...

Mai A. Kilany1; Hanaa H.A. Gomaa1; Yousry E. Abo El-magd2 and Nermin Raafat2.

...ies (ROS) in hepatocytes leading to their proliferation and triggers HCC. Manganese superoxide dismutase (MnSOD) is a nuclear-encoded antioxidant enzyme that neutralizes free radicals. Val16Ala single nucleotide polymorphism (SNP) is one of the most widely investigated SNPs in the MnSOD gene, where C to T transition resulting in the con-version of valine to alanine at amino acid 16 within the mitochondrial signaling se-quence. This study was designed to invest...

Amal Mahmoud1&2 and Medhat H. Hashem3

...us (HBV) genotype C is a leading risk factor for hepatocellular carcinoma (HCC). Eight HBV isolates from Sohag governorate, Egypt were confirmed by polymerase chain reaction (PCR), resulted in 1110 nt correspond to partial sequence of polymerase (pol) and envelop (env) genesTwo HBV isolates were associated with HCC (Sohag1 and 7). Phylogenetic analysis of the nucleotide sequence and the amino acid of the pol or env genes revealed that 7 out of the 8 isolates w...

Enas K. Abo-Elmagd,Kouka S. Abd El-Wahab,Azza H. El- Salakawy

...us infection (RV) is the leading cause of severe acute diarrhea among young children worldwide. Rapid and accurate diagnosis of RV infection is crucial for appropriate patient management and infection control. The aim of our study was to compare the diagnostic performance of Lateral flow immuno-chromatography assay (LFICA) as a rapid test for detection of RV antigen in stool specimens collected from Egyptian infants and young children with ELISA, and nested re...

Mohsen M. Elsharkawy1, Salem H. Homayed1, Mohamed M. Elsawy2 and Amr A. Khedr1

...e against CMV infection, leading to a restriction of
pathogen propagation and disease development.
...

Ljupco Angelovski*, Zagorka Popova, Katerina Blagoevska, Sandra Mojsova, Marija Ratkova Manovska, Mirko Prodanov, Dean Jankuloski, Pavle Sekulovski

...em>C. jejuni is the leading cause for food borne enteritis. Another point of attention is the change in the antimicrobial resistance of this microorganism towards some critical antimicrobials used in the human and veterinary medicine. In this study samples were taken from three points in the broiler meat production (farm, slaughter line and cold storage of the meat before shipping to the market). A total of 283 samples (cloacal swabs, caeca and carcass sw...
Muhammad Mansha1*, Sidra Yaqub1, Asma Abdul Latif2, Muhammad Wasim3 and Peter C. Thomson4
...all;">Breast cancer is a leading cause of death in women. The objective of the present study was to evaluate diagnostic utility of HER2/neu test and the association of premature termination of pregnancy with breast cancer. Two hundred breast cancer patients from INMOL hospital, Lahore (Pakistan) were interviewed on reproductive factors. HER2/neu levels were determined by ELISA fro...
Zheng Yan1,2,*, Shuang Liu2, Ai-Qing Liu2 and Hai-Yan Wang2
...he main exogenous factor leading to skin aging. The prevention and repair of UV induced skin aging has become a significant research focus over recent years. To investigate the protective effects of the oral administration of elastin peptide on photoaged skin, BALB/C Nude mice were exposed to UVA+UVB for 16 weeks to establish the photoaging model. The concentrations of elastin peptide given to the low, medium, and high dose groups were 1.5, 5.0 and 10 mg/anima...
Muhammad Farhan Qadir1, Xin-Yu Han1, Meng-li Qiao1, Qian-qian Cheng1
Raza Ali Mangi1, Ali Raza Jahejo1, Afrasyab Khan1, Yu-hai Bi1,2 and Wen-xia Tian1*
...t cells at cell surface, leading to cell death in human and animals through apoptosis. Current study was designed to investigate the expression levels of apoptosis-related genes in the H9N2 infected chicken erythrocytes. qRT-PCR and Western blot techniques were performed to determine the expression levels of apoptosis-related genes including Bax, Bcl-2 BAG-1, BAG-3 and STAT3 in H9N2 infected erythrocytes of chickens for incubation time intervals of 0, 2, 6 and...

Ruqia Bibi1, Najam-un-Nisa1, Sania Komal1, Hafiza Nimra Ghani Qureshi1, Maryam Safdar1, Hafiza Hina Jameel1, Saman Gul1, Sania Saeed1 and Inam Ullah1,2*

...tion and illegal hunting leading to habitat degradation, so there is a dire need to protect avifauna diversity for the proper functioning and stability of an ecosystem.

...
Nacira Djabali1*, Souad Dougat2, Wahida Haddadi2 and Lamis Fadhli2
...t structural differences leading to various behaviors in terms of their metabolism and their toxic effects. This work aims to study the impact of ethylene glycol monomethyl ether (EGME) on the gonadotropic axis and semen biology in the rabbit, Oryctolagus cuniculus. Thirty adult male rabbits were divided into three groups (n = 10): a control group and 2 groups treated with EGME. The solvent was applied at two increasing doses: 50 ppm and 150 ppm for fiv...

Mustafa Ozan Atasoy

...n the livestock industry leading to substantial economic loss in the worldwide economy. Recent advances in biotechnology have permitted the manipulation of viral genomes, thereby gaining a better understanding of the molecular insights of viral diseases. These have spurred the development of safer and efficient vector vaccines, which convey immunogenic genes of interest obtained from vitally important diseases. Herpesvirus of turkeys (HVT) has long been consid...

Kubilay Ucar1, Görkem Oruk2 and Sait Engindeniz1*

Zane Vincevica-Gaile1, Karina Stankevica1, Maris Klavins1, Roy Hendroko Setyobudi2, Damat Damat3*, Praptiningsih Gawawati Adinurani4, Lili Zalizar5, Muhammad Zul Mazwan6, Juris Burlakovs7
Didiek Hadjar Goenadi8,9, Rista Anggriani3 and Aamir Sohail10
 
 
...al sustainability goals, leading to reducing or abandoning the use of fossil resources and paying attention to waste utilization as secondary raw material. This paper aims to discuss general features of peat-free soil amendments as well as provide efforts into the use of secondary raw materials such as biomass ashes for the elaboration of peat-free soil-improving products. As a case example, may serve a description of the peat-free product made by rotary drum ...

Maid Zaman1*, Imtiaz Ali Khan1, Amjad Usman1 and Ahmad-Ur-Rahman Saljoqi2

...3% species which are the leading pests causing damages to agriculture, forestry, and housing/structures. Diverse ecological conditions of Pakistan made it favorable for termites which are found across the country but its diversity, genera strength, percent host and habitat attacked for district Swabi, Buner and Haripur is unreported. After collection (either on spot or through NIFA-Termaps) and identification, all districts had equal species number (05) but di...

Hams M.A. Mohamed1, Mona A. El-Zamkan2* 

...tion all over the world, leading to huge health loss. A total of 100 raw milk samples collected from small scale producers, farmers and markets at Qena city, Egypt, were examined for the presence of Streptococcus species. The preliminary identification was confirmed by using VITEK®2 system which revealed the presence of four isolates of S. thoraltensis. The antimicrobial susceptibility of the obtained isolates was detected phenotypically and genotypically,...

Laiba Ajmal1, Sidra Ajmal2, Maleeha Ajmal3, Gul Nawaz3, Rabail Hassan Toor4, Hooria Younas1, Tassaduq Hussain Sheikh5 and Raazia Tasadduq1*

... the fetus, subsequently leading to miscarriages. The functioning of human leukocyte antigen (HLA) system at the maternal fetus interface plays a pivotal role in acceptance of the fetus. Alterations in the modulated activity of HLA system influence the fetal tolerance. Therefore, this review will provide an insight on how the working of HLA at the maternal fetal interface contributes towards recurrent pregnancy losses (RPL). Antigen hiding is a phenomenon that...

Muhammad Ali Raza1*, Aneela Zameer Durrani1, Muhammad Hassan Saleem1, Kamran Ashraf2, Muhammad Muddassir Ali3, Kumayl Hassan Akhtar4 and Nazia Rubab5

...tion across the globe is leading to the increased need of food production. Due to the excessive use of common antibiotics i.e. penicillin and oxytetracycline, the antibiotic (ABs) residues remain in livestock products like milk of buffalo and cow. It leads to antibiotic resistance in human beings as well as animals and thus lead to the problem for one health (OH). Following were the objectives of the current study. Detection of commonly used antibiotics (penic...

Phassakon Nuntapanich1*, Hathaichanok Nuntapanich2 and Woraman Maicharoen3

...nism for driving society leading to organics farming production in the TKR. 

...

Tariq Mahmood1*, Shakeela Ismail1, Faraz Akrim2, Muhammad Farooq1, Nadeem Munawar1 and Muhammad Raza Khan1

... comprises of livestock, leading to human-wolf conflict. Field surveys were made on monthly basis from July 2018 to December 2019 for data collection. The distribution of the species was determined by surveying the potential habitats and recording its direct and indirect field signs (such as scats, pug marks, prey remains, hairs), while diet composition was investigated by using noninvasive technique of scat analysis. Results showed grey wolf being distributed...

Heba Abdo Basha1, Walaa Slouma Hamouda Abd El Naby2*, Samya Erian Ibrahim3, Abeer Fikry Elnahas2 

...ymous SNPs were recorded leading to four amino acid substitution in exon 1 and 2 amino acids substitution in exon 2. In low body weight, only one non-synonymous mutation was recorded at exon 2. The 3’UTR-IGF-2 sequence showed 14 SNPs in high body weight and three SNPs in low body weight. The carcass weight percentage didn’t change significantly for high or low body weight. While carcass cuts percentage increased in high body weight birds compared t...

Ali Wahdan1*, Mahmoud Ezzat1, Fatma Youssef2, Manal Munier2, Elsayyad M. Ahmed3, Marwa Abo Hashem1  

...ity to biofilm formation leading to zoonotic risk and nosocomial infections. So, this study focused on tracking the ica locus in different hosts and other virulence factors with genetic analysis of recovered isolates. A total of 350 random samples were collected from animals and hospital acquired infected patients. The recovered isolates were identified biochemically by vitek2 compact, confirmed by PCR and tested for sensitivity against varieties of antimicr...

Shomaila Sikandar1*, Imran Afzal1 and Sadaf Sarfraz2

...iseases and major issues leading to global food security. All these factors demand for extensive research for early mycotoxins detection methods and making regularity bodies to contain the spread of mycotoxins. This review summarizes the occurrence and toxicity of five major types of mycotoxins associated with food and feed and their importance in human nutrition and animal health.
...

Sidrah Ashfaq1, Muhammad Nadeem1*, Muhammad Yamin1, Talha Afzal1, Muhammad Waqar Akram1, Rabia Anam1 and Ali Mehboob2

...ountry’s resources leading indicator. World’s energy focus is shifting towards alternate renewable, cheap and environment-friendly resources that can provide long-term sustainability for survival. Due to the fossil fuels depletion and their ever-growing cost, the need to shift focus towards renewable energy resources has increased a lot. To overcome the above-said problems, there is a need to look for a feasible and robust solution for thermal appl...

Mohsin Shad1, Muhammad Usman2 and Qurratulann Afza Gardner1*

...produce abnormal protein leading to deficiencies in the complex III (coenzyme Q), resulting in defective oxidative phosphorylation and consequently effects other metabolic pathways. In the present article, we comprehensively compare the biodiversity of cyt b in bc1 and b6f complexes using in silico structural analysis tools, emphasizing that despite vast knowledge available in this field, still there are so much to explore about cyt b.

...

Sofiane Tamendjari1,2*, Farida Bouzebda Afri1,2, Lina Chaib1, Hebib Aggad3, Zoubir Bouzebda1,2 

...esistant to antibiotics, leading to therapeutic failures. It is in this context that our study aims to have an idea on the degree of hygiene of meats produced and consumed in the wilaya of Souk Ahras with respect to these strains, and to evaluate their degrees of resistance to certain antibiotics used in human and veterinary medicine
A total of 90 samples of sheep, chicken and turkey meat were collected and analyzed. Modified Baird-Parker medium was use...

Laveena Shekhawat, Sheethal S* 

...led to start immediately leading to recurrence of the parasitic hepatic cyst. Conclusion: Treatment is a combination of surgery and post-op anti-parasitic drugs. Delay in initiating albendazole therapy can lead to recurrence of the cysts in the same sites.

Keywords | Cystic ecchinococcosis, Ecchinococcus granulosus, Hepatic cyst, Parasitic cyst of liver, Liver parasite 

...

Athhar Manabi Diansyah1, Muhammad Yusuf2*, Abdul Latief Toleng2, Muhammad Ihsan Andi Dagong2, Tulus Maulana3, Hasrin4, Abdullah Baharun5 

...any regions is currently leading to the development of local bulls and Indonesia is no exception, especially in South Sulawesi Province. One of local bulls in which developed for approximately last ten years is Bali-polled bull. Thus, the selection of polled bulls is crucial, mainly in modern livestock management. The aims of this study to identify sperms post-thawing quality and proteomic plasma semen as fertility performance in Bali-polled bull. The utilizat...

Dalia Zaafar1*, Heba M.A Khalil2, Soha Hassanin3, Mohamed R. Mousa4, Mona G. Khalil1 

...nd: Cancer is one of the leading causes of death and morbidity worldwide, and it is linked to a variety of genetic and hormonal factors. Patients frequently experience cancer metastasis, relapse, and therapeutic failure despite the use of advanced therapeutic strategies for cancer treatment. As a result, many scientists are currently looking for newly repositioned drugs that can either inhibit cancer proliferation or promote cancer cell apoptosis. Methods: Thi...

Abdirahman Barre*, Karanja D Njuguna, Bebora Lilly Caroline and George Chege Gitao

...more organs with lesions leading to condemnation at meat inspection. The common gross lesions encountered were fibrin depositions 3 (1.8%), enlargement of lung 2 (1.2%), pericarditis 38 (23.7%), and hepatomegaly with nodular liver lesions 79 (49.3%), enteritis 5 (3.1%), haemorrhages and congestion of visceral organs (lung and kidney) 6 (3.7%). Histopathology of sero-reactors revealed; cellular infiltration in lymph node 9 (5.6%), hypoplasia of lymphocytes 6 (3...

Yang Hu, Jingxin Ding, Beilei Xu, Xiangming Sun, Guoyu Li, Hui Song, Zheng Zong and Wenlan Li*

...are the active compounds leading to the estrogen-like activity of TGs in vivo. In conclusion, this study is expected to provide a theoretical reference for subsequent in-depth studies on the estrogen-like pharmacodynamic material basis of TGs.

...

Muhammad Afzal Naeem1*, Muhammad Hassaan Khan2, Tahmina Nazish3, Uzma Bashir4 and Midrarullah5

...hirsutum L. is among the leading cash crop, grown at 4.7 million acreage area in Punjab province annually. The rotational cultivation of cotton and wheat crops constitutes the major cropping pattern in Pakistan. Current study was undertaken to investigate the allelopathic effect of the post-harvest remnants of cotton crop on the germination and growth parameters of successor wheat crop. Experiment was laid down in complete randomized design. The seeds (n=10) o...

Yun Zhang*

...mpsia (PE) is one of the leading complications of pregnancy that contributes to the increasing morbidity and mortality. However, the effects of exosomes secretion and expression of ET-1 and Ang-II on PE progression has not been fully investigated. The PE (n=100) and normal (n=100) women with singleton pregnancy and in the second or third trimester of pregnancy were included in the present study. The healthy group included healthy women (n=100) aged 28 to 40. T...

Atena Azarniush1, Majid Moghbeli2*, Farshid Kafilzadeh1, Mohammad Kargar1 and Hooshang Jamali1

...considered as the second leading cause of death in the world. The decreased platelet count is one of the major problems that patients face through the treatment, which makes them prone to bleeding. PRP injection therapy is a therapeutic method in use to relieve this condition. It may lead to infections due to the injection, as well as platelet resistance. Therefore, an attempt was made to find an alternative treatment, and the recombinant Interleukin 11 (IL-11...

Ahmad Shahzaib1*, Tabish Raza2 and Aisha Areej2

...m, and the lungs are the leading site of the infection. The virus spreads primarily by respiratory droplets generated by coughing, sneezing, spitting, talking, singing, or breathing of infected people. COVID-19 infection has been linked to an intense cytokine storm (CS) and the immune-inflammatory mechanism that exacerbates disease symptoms and complications. Up to 20% of the infected people need hospitalization on account of the severity of the infection, whi...

Navjot Hothi 

...utumn and winter months, leading to callousness amongst farmers about getting their livestock vaccinated. Trends suggest that this disease could resurface in the summer of 2023 and could also spread across the nation, with the fear of becoming endemic. The virus can survive for months in dark enclosures. The main culprit behind the spread of the disease is indirect transmission via vector movement, which peaks during the summer and monsoon months. Direct trans...
Umara Amir ud Din1, Waqas Ahmed Khan1*, Khurrum Shahzad1,2, Basharat Ali3, Misbah Hussain1,4 and Fazli Rabbi Awan4
...dney disease (DKD), is a leading cause of morbidity and mortality in diabetic patients. A major cause of DKD is high blood pressure (hypertension) which remains uncontrolled chronically. Renin angiotensin aldosterone system (RAAS) is a major regulator of the blood pressure, electrolytes and fluid homeostasis. RAAS plays a key role in modulating the sodium metabolism, vasoconstriction, vascular tone and renal hemodynamics. Angiotensin converting enzyme (ACE) is...

Rameez Raja Kaleri1,2*, Hubdar Ali Kaleri1, Raza Ali Mangi3, Deepesh Kumar Bhuptan4, Sana Noor5, Zainab Lanjar6, Hubdar Ali Kolachi7 Abdul Wahid Solangi1 and Sheva Dari1

... herds more efficiently, leading to overall improvements in the breed’s economic performance.

...

Alisher Safarov1*, Nasreen Nasreen4, Firuza Akramova5, Shukhrat Djabbarov1, Adolat Mirzaeva5, Javokhir Esonboev5, Djalaliddin Azimov5, Mourad Ben Said2,3 

...s diseases in livestock, leading to detrimental effects such as skin damage, weight loss, anemia, reduced meat and milk production, and even mortality. Aim: This study aimed to investigate the species composition and prevalence of ectoparasites in domestic (dogs and cats) and wild predatory mammals (jackals, wolves, foxes, and reed cats) in Uzbekistan through regular parasite collections. Materials and Methods: A comprehensive surveillance was conducted to cal...

Vui Van Nguyen1, Samorn Ponchunchoovong2, Sajeera Kupittayanant3, Pakanit Kupittayanant2* 

...ded by oxidative stress, leading researchers to investigate the impact of incorporating essential oils derived from Ocimum gratissimum leaves in order to prolong the viability of chilled dog sperm. The sperm’s characteristics were assessed using an automated sperm analyzer and a confocal microscope to analyze motility and membrane properties, respectively. Additionally, malondialdehyde production was measured to evaluate lipid peroxidation capacity. The ...
Tehreem Fatima1, Jabbar Khan1,*, Hamid Shafiq2, Dost Muhammad3, Muhammad Rafi1 and Shoaib ur Rehman1
...mal stress was the agent leading to over-expression of Hsp70 especially in longevity individuals but in longevity individuals. Whether this increased expression had any impact on longevity is still not clear that needs to be deciphered.
...

Deny Juniwati1, Hadri Latif2*, Trioso Purnawarman2, Zhang Shuqi3

 

...ird nest (EBN), with the leading destination being the People’s Republic of China (PRC). The provision of nitrite levels is less than 30 ppm for raw cleaned EBN, so the EBN is washed to reduce it. The industry generally washes EBN with reverse osmosis (RO) water, but this method does not significantly reduce nitrite levels. Therefore, an alternative method is needed. This study aimed to analyze the effect of washing using RO water combined with ultrasoni...

Mohamed Mahrous Amer1*, Hanaa Sayed Fedawy2, Hoda Mohamed Mekky2, Khaled Mohamed Elbayoumi2, Ahmed Ali El-Shemy3, Mohamed Abd El-Rahman Bosila2

...e presence of the lesion leading to increased condemnations and carcass downgrading. Clinically cellulitis is a deep infection of broiler chicken skin caused by many bacterial species, mainly Escherichia coli (E. coli) and/ or Staphylococcus aureus (S. aureus), causing severe economic losses in poultry. This study was done on 14-day old broiler Ross 308 chickens subcutaneous (s.c) injected with E. coli and/ or S. aureus to induce cellulitis. Clinical signs, mo...

Bing Yan1, Meng Meng Zhang2, Xi Chen2, Yongming Li2*, Muhammad Khan3* and Tonghui Ma1*

...ogeneous tumor formation leading to therapeutic resistance. Therefore, targeting CSCs and their associated signaling pathways is crucial for effective treatment of GBM. In this study, we showed that alantolactone (ALT) hold the capacity to suppress stem-cell-like phenotype (SCLP) of glioblastoma cells. ALT inhibited the growth, reduced mammosphere formation and down-regulated the expression of CSCs markers such as CD133, OCT4, SOX2, and NANOG in U87 and U251 g...

Jemi Diporianto1,4, Denny Widaya Lukman2*, Yusuf Ridwan3 

...al products, potentially leading to an increased risk of disease spread between regions. Trichinellosis is one of the diseases transmitted through animal-based food products. Currently, the utilization of wild boar meat has increased for feed and food purposes, making it challenging to control the movement of wild boar meat for trade. Wild boars are more likely to transmit Trichinella spp. than domestic pigs due to the lack of animal health monitoring in wildl...

Salma Jameel Askar 

...e toxicity of Meloxicam, leading us to deduce that Meloxicam induces hepatotoxicity and creates abnormalities in hematological and biochemical markers. 

...

SYED SHAHID IMRAN BUKHARI*, ZULFIQAR ALI & RIDA AHMAD

...and household activities leading
to health problems.
...
Nighat Nisar*, Hasina Maham Qadri, Asad Afridi, Muhammad Sami Khan, Muhammad Abdullah Khan
... and significant factors leading to students’ level of satisfaction towards services provided by cafeterias in public sector medical institute of Karachi, Pakistan. A cross sectional study design was adopted with a sample size of 318 round of to 400 and by using qouta sampling. A self-administered questionnaire was used to collect data regarding cafeteria use, food consumption, frequency, waiting time, cost, ambience, attitude of cafeteria staff, and cle...

Rini Widyastuti1*, Rangga Setiawan1, Nurcholidah Solihati1, Siti Darodjah1, Kundrat Hidajat1, Mochamad Ali Mauludin2, Alkaustariyah Lubis3, Mas Rizky Anggun Adipurna Syamsunarno4, Sigit Prastowo5, Takdir Saili6, Arief Boediono7

...the first estrous cycle, leading to an early first delivery age of approximately 12 months. Farmers in Simpay Tampomas Farmers Group generally had adequate knowledge of reproductive physiology but little experience in managing dairy farming goats, leading to suboptimal reproductive performance. 
 
Keywords | Dairy goat, Reproductive management, Breeding practice, Reproductive performance

Tevina Edwin, Arfa’i*, Olivio Dickresna

...tion to raise livestock, leading to a decline in the number of farmers and livestock population. The role of the government is needed to overcome the problems by distributing knowledge about good husbandry systems, providing capital to increase the scale of breeders’ businesses, providing good facilities and infrastructure for breeding in the Luak Sub-district. Farmers must focus more on their livestock business and increasing livestock productivity.

Kristina MorkÅ«nienÄ—*, RÅ«ta InsodaitÄ—, Laimutis KuÄinskas, Renata BižienÄ— 

...nce of the Mblk1 protein leading to higher brain functions in bees. In this study, we aimed to test the contribution of three Mblk-1 gene polymorphisms to the resistance to V. destructor mites. This case–control study involved 117 DNA samples that were genotyped for three single nucleotide polymorphisms (SNP) using the real-time polymerase chain reaction method. Statistical analysis was performed with SPSS Statistics 20 and PLINK software. SNP at positio...
Iko-Ojo Charity Ikwe Agada, James Agbo Ameh, Olatunde H. Olabode and Martha Echioda-Ogbole*
...this highlights CPV as a leading cause of canine gastroenteritis despite routine vaccinations in the study area. Further studies to evaluate field circulating CPV strains and the potency of available vaccines in Nigeria is hereby recommended.
...
Geeta Moolchandani1, Jaiperkash Moolchandani2*, Nasima Iqbal3
Syed Mohsin Turab4, Muhammad Kashif5 and Lubna Farooq6
...les and the risk factors leading to HIE. Data was entered and analyzed in Statistical Package for Social Science (SPSS) version 20. The mean ± SD age of mother of neonates enrolled in this study was 27.41 ± 5.44 years. Mean ± SD gestational age was 34.63 ± 3.87 weeks. Risk factors for hypoxic ischemic encephalopathy include inadequate antenatal care (33.8%), maternal anemia (35.9%), history of hypertension (35.2%), prolonged second ...

Yaseen1, Asad Ullah2*, Imad Khan2, Maryam Begum3, Sumbal Bibi3, Umber3, Namra3, Abbas Khan4, Shumaila Gul5 and Raheela Taj6

...y present in environment leading to environmental pollution. These chemicals eventually reach aquatic bodies and cause various histopathological, hematological, bio-chemical and enzymatic alterations in the bodies of aquatic organisms, especially fish, leading to huge economic loss. Consumption of the affected fishes also poses a serious health threat to humans. Pakistan being an agricultural country uses a variety of pestic...

Huda S.J1*, Nasr T.M1, Mohanad A. Al-Bayati2

...Nanohemosome. As well as leading to improved cell health and increased RBC production.
 
Keywords | Hemorrhagic anemia, Cobalt ferrite nanoparticles, Nanohemosomes, nano-medicine, Toxicity, Rabbit
...

KOUSAR PERVEEN1*, MUHAMMAD AFZAL1, SANA SEHAR1 & SYED AMIR GILANI2

...care personnel plays the leading role. However, scant attention has been paid to understand the phenomena of compassionate care in developing countries. Therefore, current study aims to conduct an in-depth qualitative phenomenological investigation from a healthcare sector of a developing country i.e., Pakistan. For this purpose, current study conducts semi-structured interviews of registered nurses of a public sector hospital. This study selects nurses as uni...
Muhammad Atif Raza1, Muhammad Tariq Javed2, Muhammad Fiaz1*, Muhammad Shakeel3, Muhammad Shahbaz Ul Haq2, Amna Kanwal2, Syeda Maryam Hussain1 and Muhammad Zubair Siddiqi4
...ive use of antibiotic is leading to the induction of antimicrobial resistance in microorganism. Main aim of this study was to find out substitute of antibiotic against Fowl Typhoid in broiler in terms of immunological, serum biochemistry and lipid profile parameters. Broiler chicks (Age = 1 d and n = 90) were kept under uniform management conditions. Chicks were divided randomly into six groups on day ten of their age with 15 replicates in each; control negati...

Nabeel Akhtar1, Owais Iqbal1,2*, Imtiaz Ahmed Nizamani1, Rehana Naz Syed1 and Abdul Mubeen Lodhi1

...lial growth of R. solani leading to 100% growth inhibition. Additionally, three fungicides, namely Systhane, Shincar, and Topsin M, were highly effective at all concentrations and caused 100% growth inhibition of M. phaseolina, followed by Antracol (87.22%) at 800 ppm. The Nativo, Evito and Moncut were moderately effective at 1000 ppm, causing more than 78% mycelial growth inhibition of M. phaseolina. Moreover, the ten fungicidal treatments were considerably e...

Fitrimawati*, James Hellyward

... This research shows the leading commodities are competitiveness and priority to be developed in West Sumatera, especially such as the beef cattle, goats and also buffalo, laying hens, broilers, local chickens and ducks. The data obtained were analyzed using the Analytical Hierarchy Process (AHP) method. This research produces the leading commodities competitively and becomes the priority to be developed in West Sumatera, su...

Amir Afzal1*, Sairah Syed1, Hafiz Husnain Nawaz2, Ruqeah Mustafa1, Marjan Aziz1, Madeeha Khan1, Azra Khan3, Uzma Javed1, Attiq Ur Rehman4, Rubab Altaf 5 and Qamar Shakil6

...ses production expenses, leading to billions of dollars in economic damages globally every year. Understanding the lifecycle of pathogens is vital in formulating effective management strategies for plant diseases. Pst has a complex life cycle that entails both sexual and asexual reproduction, facilitating the rapid evolution of new strains. The evolution of new races is primarily driven by the selection pressure imposed by the deployment of resistance genes in...

Basheer Ahmad, Nowsherwan Zarif, Saif Ullah Khan, Salman Ahmad and Anwar Ali*

...w, reaching 208 million, leading to increased pressure on food production and forest resources. To tackle this problem, there is a pressing need for effective food structures that not only improve efficiency and financial outcomes but also bring about positive ecological impacts and gain social acceptance. Traditional land management practices like agri forestry offer a promising solution in Pakistan. To plant trees on private lands, agroforestry enables pure ...
Muhammad Farooq1*, Lal Badshah2 and Sanam Zarif1
... with 6 species were the leading families. Mimosaceae (5 spp.) Caryophyllaceae (4 spp.) were the next dominant families. The other families had either 3 or less than 3 species. Biological spectrum of flora indicated that therophytes (34 spp., 36.5%), followed by nanophanerophytes (16 spp., 17 %) were the dominant. Similarly, hemicryptophytes (14 spp., 15%), chamaephytes (11 spp., 11.8%), microphanerophytes (10 spp., 10.7%) and geophytes (8 spp., 9%) were the o...
Islam Ullah Shah, Anwar Ali, Ayaz Khan and Sultan Muhammad
...n all four stands as the leading dominant specie. Average Density of all stands was calculated as 342.88 trees/ha with basal area 55.34144 m2/ha. The average volume of all stands was calculated as 132.324m3/ha. The distribution of Pinus gerardiana is satisfactory in almost all the stands however the distribution of associated species are poor. Due to poor distribution and gaps in small size middle and in large classes, Juniperus...
Bashir Ahmed Wani1, Shakeel Haider Zaidi2, Hakim Shah3 and Muhammad Muslim4
... and used by a number of leading manufacturing units of Greco-Arabic, Homeopathic medicines as well as allied food processing and cosmetic industries.

Keywords: Marketing potential, Herbal drugs, Medicinal plants.

...
Muhamamd Arif Chaudhary and Ejaz Ahmed
...ak in cross sections are leading to the conclusion that there have been the possibility of some fungal attack resulting in blockage of conducting tissues, causing heart wood rot followed by termite attack and elimination of Rahizobial nodulation. Therefore, it is suggested to carry out an intensive field survey; study the biology, physiology and ecology of the suspected fungi and Rhizobial nodulation pattern.

...
Shams-ur-Rehman, Altaf Hussain and Riaz A. Khattak
...ral developing countries leading to little or no progress in this direction Involving local communities in reforestation and selection of suitable species in combating salinity seem to be one of the economically viable approaches to reduce poverty as several million ha. area has been severely hit by this menace in many countries of South Asia. The paper describes the screening/selection of species following use of some soil amendments to successfully establish...
Kh. Rizwan Shehzad, Z. H. Malik and Rizwana Aleem Qureshi
...s were named after the 3 leading dominants. The following five communities were recognized: (I) Melia-Lantana-Stellaria, (II) Morus-Dodonaea Melilotus, (III) Dodonaea-Grewia-Melia, (IV) Stellaria-Zizyphus-Dodonaea, (V) Oxalis-Pinus-Olea Communities. Index of diversity and its components decreased from low altitude to high altitude, but in Oxalis-Pinus-Olea community it was high. Soils were generally loamy, sandy loamy ...
Zakaullah
...exudation and eventually leading to the death of entire plant. The dead wood was found attacked by the borers (insects)....
S. M. Chughtai, Jehandar Shah, Syed Zahir Shah and Sardar Hussain Shah
...m spontaneum was the leading dominant; on relatively drier sites, Astragalus graveolens took the lead over; and in more wet habitats, Salvia-Polypogon community dominated the scene. The stable land was dominated by Cynodon-Imperata community representing a relatively a advanced stage of succession....
Dr. K. M. Salim and Gul Shahid
... ft.) near the main road leading to Nowshera. The Cherat hills are barren, mountaineous and rocky with few level plains. Cherat is a cantonment town built by the British Army authorities in 1865. The forests around the cantonment were declared as Forest Reserve in that year and protected from felling, grazing and other disturbances. There are other villages in the area, which are connected to one another by narrow and difficult paths, and by modera...

Muhammad Ali Raza1*, Wali Ullah Falahi2, Aneela Zameer Durrani3, Bilques Bano4, Muhammad Muddasir Ali3, Nazia Rubab4, Syed Tasadak Mehdi4, Muhammad Wasim Iqbal5, Kumayl Hassan Akhtar6, Aqeel Raza7, Muawuz Ijaz3, Ujala Fatima Shan3, Muhammad Aftab3

...tion across the globe is leading to the increased need to produce food. The high value of livestock products and their increasing demand creates a niche for the consumption of a variety of livestock products, which contribute to the food security (Lindahl et al. 2019). Due to the excessive use of common antibiotics (penicillin and oxytetracycline), the antibiotic residues remain in livestock products like meat (beef, mutton and chicken), it leads to antibiotic...

Muazzam Hashmi1, Braima Pascal Komba1, Muhammad Waqas Alam Chattha2*, Almazea Fatima1, Muhammad Farooq Hyder3

...cilities like good roads leading to the farms and storage facilities are made available to the florists for suitable marketing.

...

Riam Yousfe Muttair 

...y also creates the doors leading us to the mechanism of the development of cancer cells as well as the immune system that can kill the cancer cells. Checkpoint inhibitors, the main pillars of the immunotherapy, are explored in a detailed manner taking into account some of the most important checkpoint pathways and their clinical implications. Next-generation checkpoint inhibitor is the same thing as opening new ways in which the success of cancer immunotherapy...

Saddam Hussain1, Muhammad Asrar2*, Usama Saleem2, Dilbar Hussain3, Muhammad Sohail Qadir3, Muhammad Saleem3, Rashid Ali2, Zeeshan Javed2 and Mubshar Saleem4

...susceptible to termites, leading to an acute shortage of animal feed. In this review, we tried to reveal all about the damages of termites in agriculture of Pakistan. 

...

Shoaib Zawar1, Muhammad Waqas Yonas1,2*, Muhammad Mujahid Akbar1 and Abeer Ahmad1

...nhanced grain formation, leading to higher grain yield (5562.38 kg ha-1 in 2020-21 and 5220.22 kg ha-1 in 2021-22). Adapting an appropriate sowing method is crucial to maximize wheat production which has been proved in the augmented furrow method over a broadcast and/or the usual drill sowing methods. The relatively better performance of augmented makes it the preferred choice for enhancing per unit area productivity. Findings of this study can hold a signific...

Wadood Shah* and Sanam Zarif Satti

...duce water availability, leading to a variety of problems, including the ongoing limited water condition. The present review article intends to critically analyze morpho-physiological and growth, responses of plants to various levels of drought stress as well as their ability to regulate and alleviate the negative consequences of low water availability. Meeting the world’s population’s continual increase in food consumption is hampered significantl...

Hafizuddin1, Sri Wahyuni2, Tongku Nizwan Siregar1*, Amalia Sutriana3, Ririn Triyuliani4, Siti Hanyyah Herviani4, Muhammad Farhan Syuhada4, Nur Salimah4, Muharni Mardiah Eriswandi4, Ratu Permata Ayu4, Putroe Hayatun Nufus4

... by several limitations, leading to a wide variation in the resultant response. To overcome these limitations, several studies have recommended the use of bovine pituitary extract (BPE) as an effective alternative in improving animal reproduction. Therefore, this study aims to determine the ovarian and hormonal responses of local rabbits after superovulation induction with BPE. The sample comprised of 1 local male rabbit and 9 local female rabbits with a histo...

Husnurrizal Husnurrizal1,2, Hafizuddin Hafizuddin2*, Sri Wahyuni3, Cut Nila Thasmi2, Tongku Nizwan Siregar2,4 

... addition, the mechanism leading to increased spermatozoa concentration after administration of PGF2 has not been clearly explained. Therefore, this research aimed to assess the impact of the time interval between PGF2α administration and semen collection on the enhancement of spermatozoa quality, testosterone, cyclic adenosine monophosphate (cAMP), and adenosine triphosphate (ATP) levels. A total of 15 rats (Rattus norvegicus) categorized into five trea...

Journal of Animal Health and Production

June

Vol. 12, Iss. 2, Pages 121-275

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