Effects of Clomiphene citrate on Reproductive System of Birds and Mammals
Effects of Clomiphene citrate on Reproductive System of Birds and Mammals
Muhammad Zubair, Sajid Mahmood Sajid
ABSTRACT
Clomiphene is a non-steroidal fertility medicine. It causes the pituitary gland to release hormones needed to stimulate ovulation. Clomifene is useful in those who are infertile due to anovu- lation or oligoovulation. Clomifene inhibits estrogen receptors in the hypothalamus, inhibiting negative feedback of estrogen on gonadotropin release and leading to up-regulation of ovulation. It has useful effects on the reproduction of female in terms of reduction in puberty and ovulation induction. The beneficial effects are manifested in male in terms of improvement of semen.
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