Ambreena Hafiz1, Tanzeela Riaz2 and Farah Rauf Shakoori1*
...ffect of deltamethrin on metabolic profile of 4th, 6th instar larvae and adult beetles of deltamethrin-resistant populations of T. granairum collected from wheat godowns of Gujranwala, Okara and D.G khan has been studied in current investigation. The toxicological data generated from deltamethrin-resistant populations was compared with deltamethrin-susceptible population that has not been exposed to any insecticide since thirteen years. From analysis of
Shakeel Ahmed* and Sarwat Jahan
...ction in both normal and metabolically stressed conditions. NMS administration induced a significant (P<0.01) increase in resistin levels, while suppressed leptin (P<0.05) secretion in both fed and 48-hrs fasting conditions. In conclusion our study suggested that NMS has a role in regulation of adipokines secretion. Its inhibitory effect on leptin and stimulatory effect on resistin shows an important relationship between NMS and adipokines in the regulat...
Physiological Responses to Fasting and Refeeding in Apodemus chevrieri from Hengduan Mountain Region
Hai-Ji Zhang1, Di Zhang2, Dong-Min Hou1 and Wan-Long Zhu1,*
...d body fat mass, resting metabolic rate (RMR), organs morphology, serum leptin levels and food intake were measured in the present study. The results showed that food deprivation decreased body mass and body fat mass. After refeeding, body mass can not be returned to the control value on refeeding 12 h, and it returned to control level on refeeding 7 days, but body fat mass can not be restored to the control level on refeeding 7 days. RMR and mass of liver dec...
Wenqiao Hui1, Jishun Tang1, Dejian Zhu1, Qian Ban2* and Sheng Chen1*
...leptin act as a critical metabolic cue linking adipose and the onset of puberty. In the present study, we first assessed the morphological changes in adipose tissue at pre-puberty and puberty onset stages of goats, and then determined the role of leptin to activate signaling pathways which modulate the expression of hypothalamic genes involved in reproduction and metabolism. We found that leptin significantly upregulated the LEPR in the adipose tissue of goat ...
Farah Ashfaq* and Tasnim Farasat
...p of serum resistin with metabolic markers in obese Pakistani subjects. Anthropometric parameters including age, body mass index (BMI), waist circumference, waist-hip ratio (WHR), diastolic and systolic blood pressure, lipid profile and fasting glucose, serum resistin and insulin of three hundred over weight, obese males and females, 17 to 30 years and 100 comparable control subjects were included. Serum resistin and insulin, fasting glucose, triglycerides and...
Ibrahim A. Alhidary1,*, Mutassim M. Abdelrahman1, Riyadh S. Aljumaah1, Abdullah H. Alyemni2, Moez A. Ayadi1,3 and Mohamed Y. Al-Saiady2
...F on growth performance, metabolic profile and rumen characteristics in Naemi lambs. Fifty growing Naemi lambs at age of three months with an average bodyweight of 27.77 ±1.09 kg were randomly distributed to five different treatments, ten lambs each, as follow: 1. Alfalfa hay and barley grain (ABG); 2. Pelleted alfalfa hay and barley (PAB); 3. TMR1 (25.67% NDF); 4. TMR2 (30.88% NDF); and 5. TMR3 (55.93% NDF). Lambs were housed in an individual pen for 9...
Muhammad Saqlain1, Humaira Kalsoom1, Muhammad Fiaz1,2, Abid Mahmood1, Rizwan Aziz Qazi4 ,Waseem Safdar5, Pakeeza Arzoo Shaiq1,Bernard M.Y. Cheung3 and Ghazala Kaukab Raja1,*
..., obesity, diabetes, and metabolic syndrome (MetS). In this study the association of Ala54Thr polymorphism with MetS and its risk components was studied in a local Pakistani population. MetS subjects and controls were recruited from out-patient departments of Pakistani hospitals. Ala54Thr genotyping of 200 MetS patients and 200 healthy controls was performed using a PCR-RFLP. Genotype and allele frequencies were calculated and computed for genetic associations...
Tania A. Shakoori1,*, Soumble Zulfiqar2, Khadija Irfan Khawaja3 and Faisal Masud4
...r pathways involving key metabolic regulator molecules. However, the effect of NaB on Sirt1/AMPK and Akt/mTOR axes is not reported. We compared genetic expression of Sirt1, AMPK, Akt, and mTOR in adipose tissue from mice treated with NaB versus placebo. Four groups of mice (n=27) mice were administered oral NaB, intraperitoneal (i.p) NaB, oral placebo or i.p placebo for 16 days. RNA was isolated from the epididymal fat pads and relative genetic expression of A...
Doulat Baig*, Fida Mohammad Abbasi*, Habib Ahmed*, Maqsood Qamar** and Muhammad Ayub Khan**
RESPONSE OF SUNFLOWER HYBRIDS TO DIFFERENT NITROGEN LEVELS FOR PHYSIOLOGICAL AND AGRONOMICAL TRAITS UNDER FIELD CONDITIONS
...basic requirement of the metabolic processes for the vegetative, reproductive growth and yield of the crop. The protein is wholly dependent upon the amount of nitrogen fertilization available in soil for the plant use. A two year study was conducted in 2012 and 2013 at National Agricultural Research Centre (NARC), Islamabad, Pakistan. The experiment was aimed to –1 –1 evaluate the effect of different nitrogen (N) levels (N = 0 kgha , N = 60 kgha , ...
Xiaopeng Tang1,3, Rong Xiang1, Sijia Chen1,3, Shufen Yang1,3, Hu Liu1,3, Rejun Fang1,3,* and Aike Li2,*
...the AA digestibility and metabolic energy of fermented cottonseed meal (FCSM) and enzymatic hydrolyzed cotton seed meal (EHCSM) in white leghorn roosters. Firstly, CSM were fermented with Aspergillus niger, or hydrolyzed with alcalase and flavourzyme. Secondly, a total of 32 white leghorn roosters with similar body weight (1.95± 0.14 kg) were randomly assigned into 1 of 4 treatments, 1) starvation group, 2) untreated CSM group, 3) FCSM group...
Chuanpeng Zhou1, Heizhao Lin2,*, Zhong Huang2, Jun Wang1, Yun Wang1 and Wei Yu2
..., and increasing glucose metabolic burden in this species. ...
Ambreen Asghar, Tasleem Akhtar, Nadeem Sheikh*
... to an alarming ratio of metabolic disturbance and obesity. Despite the genetic regulation of metabolic responses, a close relationship between high energy food-intake and increased body-weight has been reported to support several pathologies in the metabolic and immune system. Present work was designed to evaluate the variations in serum protein level induced by fat rich diet. For this pu...
Mei Li1, Di Zhang2 and Wan-Long Zhu1,*
...esis, changes in resting metabolic rate (RMR), nonshivering thermogenesis (NST) and energy intake were measured in Eothenomys miletus fed diets containing 0, 3.3% and 6.6% tannic acid, respectively. The results showed that E. miletus fed the diets with 6.6% tannic acid increased RMR compared with control on day 14, and reduced the gross energy intake (GEI) and digestible energy intake (DEI). On day 28, E. miletus fed diets containing tanni...
Farah Rauf Shakoori1,*, Anum Feroz1, Ayesha Gondal1,Sahar Akram2 and Tanzeela Riaz3
...compared to control. The metabolic derangements induced by sub-lethal dose of λ-cyhalothrin suggest that infestation caused by T. granarium in godowns could be overcome by calculating lethal dose of λ-cyhalothrin.
...
Souheila Slimani1,*, Sonia Hamouda1, Chahrazed Souadi1, Sara Silini2, Cherif Abdennour2 and Leila Delimi3
...he appearance of certain metabolic, carcinogenic, neurotoxic and fertility disorders. The objective of this work is to study the toxic effect of the dithiocarbamate “thiram 80% purity” on seasonal reproduction of male domestic pigeons Columba livia domestica, subjected to a long photoperiod (19L: 05D). The fungicide was orally administered at 5 and 10 mg/Kg body weight/day for 10 consecutive weeks.Testicular volume and weights were measured ...
Farah Rauf Shakoori1,*, Tanzeela Riaz2, Uzma Ramzan1, Anum Feroz1 and Abdul Rauf Shakoori2,3,*
...compared to control. The metabolic derangements induced by sub-lethal dose of esfenvalerate suggest that infestation caused by T. granarium in godowns could be overcome by calculating lethal dose of esfenvalerate.
...
Shabana*, Saleem Ullah Shahid and Shahida Hasnain
Muhammad Asam Riaz1, Javeria Choudhary1, Muhammad Zeeshan Majeed1*, Muhammad Afzal1, Sohail Ahmed2 and Muhammad Sajjad Khalil1
Nimra Naseer, Adeela Fatima and Imran Sajid*
...ce of unique and diverse metabolic compounds. The study predicts that the seactinomycetes strains are a potential resource to cope up with evolving multi drug resistant pathogens. Furthermore, these secondary metabolites can be identified by comparative studies and these actinomycetes can be grown on larger scale to obtain high yield of potentially useful secondary metabolites.
...
Tahira Jamil*1, Mohammad Asghar1, Fatma Husain1, Haq Nawaz Bhatti2
...n is formed as secondary metabolic intermediate initiated by anion moiety (acetate) through polyketide chain reactions. The current work was put away to investigate the potency of Pleurotus strains for statin formation by cultivating them on lignocellulosic substrates (wheat straw, rice straw, banana stalk) in SSF for 8 days. Among Pleurotus species (P. nebrodensis, P. sepidus, P. spodoecus), P. spodoecus expressed bes...
Mehboob Arslan* and Xin Yang
...pulate specific cellular metabolic pathways that aid the production of viral particles. Viruses need to breach a complex network of metabolic intrinsic factors and microenvironment established within the host cells. The pressure exerted by invading pathogen disrupts the internal balance and dictate the host-pathogen niches. For absolute survival, proliferation, and propagation inside the host cell, viruses modulate certain <...
Shakeel Ahmad Anjum1, Sami Ullah1*, Muhammad Mohsin Raza2, Mohsin Raza1, Muhammad Abbas3, Ijaz Ahmad4, Malik Muhammad Yousaf2, Muhammad Zeshan5, Adeel Abbas1, Mehmood Ali Noor1 and Mohsin Nawaz1
...ng post-vegetative plant metabolic activities during grain filling, in contrast to late application rate. ...
Rabia Khalid1, Saleema Bashir Shams1, Bibi Nazia Murtaza1,*, Gaitee Joshua1, Saira Mushtaq1, Hassan Al-Talhi2 and Abdulaziz Al-Amri2
...eveals the components of metabolic syndrome among the bank employees in Lahore area of Pakistan. Total 530 male individuals were recruited in the study. Associations of physical activity and sedentary behaviors with the tendencies of metabolic syndrome were evaluated. The experimental and laboratory values for BMI, total cholesterol (TC), total triglycerides (TG), high density lipoproteins (HDL), low density lipoproteins (LD...
Yue Ren1, Peng-Fei Liu2, Wan-Long Zhu1,*,Hao Zhang1 and Jin-Hong Cai1
...sons. Body mass, resting metabolic rate (RMR), nonshivering thermogenesis (NST), food intake, serum leptin levels and hypothalamic neuropeptide Y (NPY), agouti aelated peptide (AgRP), pro-opiomelanocortin (POMC), cocaine and amphetamine regulated transcript (CART) expressions were measured. The results showed that body mass and serum leptin levels were lower significantly in winter than that of in summer in five areas. But thermogenic characteristics and food ...
Shad Mahfuz1,2, Shuyuan Wang1, Mo Chen1, Fei Zao1, Dong Zhen1,
Zhongjun Liu4 and Hui Song1,3*
...e, egg quality and serum metabolic profile during the early phase of production.A total of 105 ISA Brown 18 wk old laying hens were grouped into 5 treatments with 7 replications of 3 hens each. Dietary treatments included a basal diet as control; antibiotic (0.05% flavomycin); 2% FVW; 4% FVW; and 6% FVW for 8 wk. Data were subjected to one-way analysis of variance using SPSS software followed by Duncan’s test probability of p<0.05. During the e...
Rimsha Munir1, 2*
... proliferation rates and metabolic stress in 2D and 3D cell culture systems. Two cell line models (HepG2; liver cancer cell line and HCT-116; colorectal cancer cell line) were selected that showed inverse proliferation trends under 2D and 3D cell culture systems: HCT-116 displays decreased, while HepG2 displays increased proliferation rates under 3D system. The presented data indicated that the proliferative capacity of the given cell line was associated with ...
Fariha Latif1*, Muhammad Javed2, Hammad Ahmad Khan2 and Khalil-Ur-Rehman3
...d be due to its actively metabolic nature. Pb can inhibit the functional properties of CAT by disrupting disulfide bond. Moreover, the interference of Pb in the activity of SOD was also reported during present investigation. Therefore, this study provides an insight in rational use of antioxidant enzymes as biomarkers of oxidative stress in the bio-monitoring of aquatic pollution.
...
Peng Peng1,3, Xiaopeng Tang2*, Dun Deng3, and Rejun Fang1*
...tter (DM) digestibility, metabolic energy (ME) were determined. Secondly, a total of four hundred eighty 15-day-old Shuanggui-tou meat ducks were divided into 4 treatments, 1) Control group (0% GM in the diet), 2) 3% GM group (3% GM in the diet), 3) 6% GM group (6% GM in the diet), and 4) 9% GM group (9% GM in the diet). All groups had 8 replicates and 15 birds were included in each replicate. The experiment lasted for 28 days. The average daily gain (ADG...
Shaista Abbas1,Imtiaz Rabbani1, Hafsa Zaneb2, M. Shahbaz Yousaf1, Saima Ashraf2, Abid Hussain Shahzad3, M. Afzal Rashid4 and Habib Rehman1,*
.... It is characterized by metabolic stress, reduced feed intake, intense mobilization of energy reserves, increased nutritional requirements and changes in dams’ metabolism. Yeast Supplementation has been found to increase the production performance and nutrient digestibility in ruminants. However, when compared with large ruminants there is scarcity of the data reporting the effects of dietary yeast in transition goats. Therefore, a trial was planned to ...
Anila Latif, Zaheer Abbas, Farhatullah and Ghulam Muhammad Ali*
...ation concludes that the metabolic engineering of berberine in plants is an effective strategy to protect plants from herbivorous insects and this pathway should further be evaluated for possible application in agriculture. ...
Wajiha Anum1*, Liaquat Ali1, Umair Riaz2*, Abid Ali1, Nadia Manzoor3, Laal Hussain Akhter4, Asad Ur Rahman5, Naeem Maan6 and Ijaz Ahmad7
...sis, and continuation of metabolic function in plants. However, it is not readily available to the crop because of its immobile nature. In order to ensure its efficient uptake by crop, an experiment was conducted to appraise the effect of various P placement methods and fertilizer rates on wheat. The fertilizer treatments were F1=150-00-60 NPK kilogram/hectare, F2=150-30-60 NPK kilogram/hectare, F3=150-60-60 NPK kilogram/hectare, F4=150-90-60 NPK kilogram/hect...
Xuya Zhou1, Ying Liu1, Deqin Xu1, Jie Bao1, Yaru Cao2 and Yong Jin3*
...ugh the arachidonic acid metabolic pathway CYP450.
...
Zhen-Yang Wu1, Li Li1, Yu-Hua Fu2, Sheng Wang3, Qing-Ming An1, Xiao-Hui Tang4, Xiao-Yong Du3,5,* and Fei Zhou6,*
...dquo; and “pigment metabolic process”. KEGG pathways were analyzed for the differentially expressed genes and show that Melanogenesis signaling pathway may affect the process of coat color formation. Quantitative PCR confirmed differential expression of thirteen genes, TYR, TYRP1, TYRP2, MITF, β-catenin, Wnt3a and so on. These results will expand our understanding of the complex molecular mechanisms of coat color in Tibetan sheep and provide a...
Baochao Liao1,2, Xiujuan Shan2,3* and Yunlong Chen2,3
...seful for predicting the metabolic responses of individuals or populations to environmental change.
...
Muhammad Usman Ghazanfar1, Waqas Wakil2, Shahbaz Talib Sahi3, Waqas Raza1* and Mahmood Ahmad Randhawa4
...ext-align: justify;">The metabolic changes that took place during host-pathogen interaction have been poorly investigated. Although photosynthesis disturbance and carbon metabolism re-programming have been studied yet, there is scary of data on plant amino acids after induction of resistance. Here we investigated the amino acid contents in induced and un-inoculated and invaded region after induction of resistance. The quantities of methionine, iso-leucine, leu...
Tanzeela Riaz1, Farah Rauf Shakoori2*, Syed Shahid Ali2 and Mushtaq Ahmad Saleem1
... These phosphine induced metabolic alterations over varying exposure intervals may be helpful in controlling this insect pest by monitoring period of fumigant exposure.
... 
