Inquisition of Variations in Serum Protein Profile Induced by Fat Rich Diet in Rattus norvegicus
Inquisition of Variations in Serum Protein Profile Induced by Fat Rich Diet in Rattus norvegicus
Ambreen Asghar, Tasleem Akhtar, Nadeem Sheikh*
ABSTRACT
Growing rate of high fat diet consumption can lead to an alarming ratio of metabolic disturbance and obesity. Despite the genetic regulation of metabolic responses, a close relationship between high energy food-intake and increased body-weight has been reported to support several pathologies in the metabolic and immune system. Present work was designed to evaluate the variations in serum protein level induced by fat rich diet. For this purpose, two groups of Wister rats were fed with diets carrying difference in percentage of fats. Protein profiling of treated groups indicated a marked increase in serum protein (related to iron metabolism and immune response) level compared to low fat-fed rats. Additionally, a decreased level of serum proteins was observed in the serum compared to control rats. Taken together, our findings conclude that diets rich in fats result in dysfunction of immune system and iron metabolism.
To share on other social networks, click on any share button. What are these?
June 2018
Vol. 33, Iss. 1, Pages 1-97
