Sania Subhan Qureshi, Mian Saeed Sarwar and Zahir Shah
... regular dressing of the wound with antiseptic. Antibiotics and analgesic was recommended for 3-5 days respectively. As per feedback of the owner, the wound was healed and no complication was reported from the owner....
Saba Irshad1,*, Ayesha Ashfaq1, Ammara Muazzam1 and Abida Yasmeen2
... and to treat infectious wounds. Their crude ethanol and methanol extracts were tested against five important bacterial and fungal strains. Both extracts showed maximum antibacterial activity against B. subtilis, E. coli and S. aureus. All alcoholic extracts were competent enough to reduce the growth rate of M. canis and A. flavus up to 35%, with no inhibitory influence on Candida species and F. solani. These ex...
A. N. Naqvi and K. Fatima*
INCIDENCE OF LIVESTOCK DISEASES IN NOMAL AND NALTAR VALLEYS GILGIT, PAKISTAN
...arasites, ectoparasites, wounds, hematuria, respiratory diseases, emaciation, hemorrhagic septic-emia, tumour, blue tongue, cow pox, enterotoxaemia, tetanus, paralysis and arthritis. In precise, endoparasites were found in 25.3% animals followed by respiratory diseases (24.74%). Most of the cattle (2053) and sheep (926) were found affected with endoparasites, whereas most of the goats (3960) were suffering from respiratory disorders. The seasonal data indicate...
Riffat Mehboob1*, Sami Ullah Mumtaz2, Zoya Manzoor3, Sajid Abaidullah2, Fridoon Jawad Ahmad1
Deranged biochemical and hematological profile of septicemia patients in Mayo hospital, Lahore
...t infection (12.87%) and wound infection (7.92%). According to this study, diabetes (45.56%) was the main comorbidity of septicemia. Most of the patients were between 51-70 years while septicemia occurred equally in both genders. Major predictors for diagnosis were WBCs, hemoglobin, AST, ALT, ALP, urea and creatinine. Other biomarkers gave no information regarding septicemia diagnosis. This demands the use of improved diagnostic biomarkers in developing countr...
Muhammad Aslam Rajput1,3, Imtiaz Ahmed Khan2, Rehana Naz Syed3 and Abdul Mubeen Lodhi3*
...s, i.e., dipping, paste, wound+paste, soil infestation, spraying and injection methods for the establishment of smut disease. It appears that disease expression was significantly influenced by pathogen inoculation method. The infection caused by S. scitamineum and subsequent whip smut development has also been greatly varied with the inoculation method. Injection method followed by wound+paste method and dipping method produ...
Muhammad Naeem Khan* and Asad Jan
... problems and healing of wounds. The aim of the study was to explore phytochemical constituents of methanolic crude extract (MCE) and various solvent fractions and in-vitro antimicrobial activities of whole plant of D. botrys. Qualitative phytochemical screening of MCE and solvent fractions of D. botrys showed the presence of alkaloids, phenols, flavonoids, saponins, tannins and sterols, however in n-hexane fraction (HxF) only flavonoids and saponins were dete...
Sana Khan1, Raheela Taj1, Noor Rehman2, Asad Ullah3, Imad Khan3 and Sadeeq ur Rahman3,*
...e 58.46%, pus 33.85% and wounds 7.69%, respectively. More samples from females (n=70) than males (n=60) with majority (43.08%) from age group 21-40 years were found positive for C. freundii. Of the 130 isolates, 28 (21.53%) were ESBL producers comprised of 10 (35.71%) from males and 18(64.29%) from females with majority recovered from age group of 21–40 years (57.14%). Furthermore, 10(7.69%) isolates were metallo-β lactamase (MBL) prod...
Pravin Mishra1, Md. Muket Mahmud2, Md. Ahosanul Haque Shahid2, Alamgir Hasan2, Vivek Kumar Yadav3 and Moinul Hasan1*
...alf brought with myiasis wound and bacteria associated with myiasis wound was studied and further molecular detection confirms the presence of methicillin-resistant Staphylococcus aureus from the outer part of the wound but not from the inner part. The study helps and aware the veterinarians, health-workers, and general people regarding the situation of antibiotic resistance. As maggot hel...
Farid Ullah Khan*
MINIATURE VIBRATION SHAKER FOR MEMS-SCALE VIBRATION-BASED ENERGY HARVESTERS APPLICATION
...lanar beams and a copper wound coil is contained at the lower portion of the shaker’s table. Alternating magnetic field of the wound coil and the magnetic field of the permanent magnet generates a sinusoidal force that causes the shaker’s table to vibrate at the frequency of input electrical signal to the shaker. Modal analysis of the suspension system performed in COMSOL Multiphysics®, indicates that in the ...
Safia Arbab1, Rehana Buriro1, Shams Uddin Bhugio1, Atta Hussain Shah2, Jamila Soomro3,Qudratullah Kalwar4, Saqib Ali Fazilani1 and Waseem Ali Vistro5*
...t pathogens found in the wounds of donkey. For this purpose, two different concentrations 30 µl and 60 µl crude as well as ethanol extract of Aloe Vera were used. During this experiment, total 50 wound samples were collected from donkey wounds. All 50 samples were found contaminated with different bacterial organism, among all those 45, 35, 33, and 25 were recorded positive for...
Taqiur Rahman1, Tabassum Yaseen1*, Ali Mujtaba Shah2, Samiullah3, Ghulam Jelani3, Gul Nawaz1,Qudratullah Kalwar2
...i>use for the healing of wounds, Arisaema jacquemontii blume used as antidote, Artimizia annua used asanathematize also in gastric problems, Avena sativa L. used as a laxative and antiseptic (R1).
Eslam Moradi-Asl1*, Behnam Mohammadi Ghalehbin2, Kamran Akbarzadeh3, Jafar Mohammad-Shahi4, Hajar Afshin4
...n fly larvae infect open wounds. We describe an old male with wound myiasis by agent of Lucilia cuprina, who had a history of diabetes and also blind that reefed to hospital in 13 September and was admitted to date 18 September 2019.Larvea extracted manually from thumb finger of left foot and sent to Medical Entomology Laboratory of the School of Public Health, Ardabil University of medical Sciences for identification...
Qiang Tang1 and Qianli Tang2*
...nism of isoliquiritin on wound healing in scalded rats. The results show that at 24 h after the last administration, wound healing rate of isoliquiritin group was higher than that of model group (p=0.024). Compared with control group, thickness of epidermis and dermis in model group was thinner (p<0.001), and width of subdermal collagen fibers also decreased (p<0.001), inflammatory factors TNF-&alp...
Bingjie Zhou1, Hitesh Bhagavanbhai Mangukiya1, Siva Bharath Merugu1, Fakhar-un-Nisa Yunus1, Yuchen Fan1, Zhenghua Wu1,* and Dawei Li1,2,*
...y cell proliferation and wound healing assays, while the auto-fluorescent property of DsRed was confirmed by fluorescence microscopy and immunofluorescence. The potential application of his-AGR2-DsRed was demonstrated by its internalization in fibroblasts. Therefore, the purified recombinant fluorescent protein would be a very useful tool for further investigation of AGR2’s extracellular function and molecular mechanism.
... 
Hafiz Muhammad Tahir*, Iram Liaqat*, Junaid Nadeem, Hammad Aamir and Shaukat Ali
...t was frequently used as wound dressings. In recent years, several studies have investigated the alleged antibacterial potential of spider silk but the results have largely been inconclusive. The studies either failed to consider the inhibitory effects of the processing chemicals or did not investigate whether the inhibitory potential is an intrinsic property of silk or is due to the aggregate gland secretion coating its surface, hence a borrowed property. Our...
Yonis Abukar Mohamed1, Shafii Abdullahi Mohamed1,2, Abdiaziz Idiris Mohamud1,3*, Abdiaziz Ahmed Mohamud1,3, Kassim Abdullahi Jimale1,2 and Said Ali Ibrahim2
... either healed or active wounds (skin lesions), 17.4% scars, and 28.0% both skin lesions and scars. Moreover, dermatological diseases were also encountered, habronemiasis 59.1%, ectoparasite 35.7%, Sarcoid 5.1%. Results that were obtained from the indirect assessment of donkeys’ welfare indicated that most donkey owners in the region have little or no knowledge and information on donkey’s welfare matters. Limitation of taking sick donkeys to veteri...
Muhammad Awais1,2, Waqas Ahmad3, Akhtar Rasool Asif4, Sayyed Aun Muhammad1, Iahtasham Khan1*, Muhammad Amjad Ali5, Muhammad Qaiser Riaz1 and Muhammad Saqib2
... illnesses and healingof wounds. A total of 40 rabbits were divided into four groups (A, B, C, and D) to perform two experiments. Two wounds of full-thickness with the dimensions of 1×1 cm (1 cm2), were created on right and left lateral sides of the trunk, comprising 4 wounds on each rabbit. Wounds of group A, B, C and D were treated wit...
Nabila Rasheed1*, Bushra Waseem1, Kanwal Haneef2, Shumaila Usman3, Madeeha Sadiq1, Tabinda Urooj1, Sarah Tarique2 and Dabeeran Zeha4
...lue exclusion method and wound healing potential by scratch assay method. Healing of the scratch was observed at different time intervals (0h, 6h, 24h, 48h). The images were analyzed by Image J software. Morphological analysis was done under inverted microscope. Results showed that with each passaging stage the viability of GDM cells remained normal whereas Wound healing potential of GDM-WJMSCs was decreased as compared to c...
Sharjeel Saif1, Asghar Ali Kamboh1*, Ghulam Mustafa Solangi2, Rehana Burriro3, Hasina Baloch1, Atta Muhammad Memon2
...(like swelling, abscess, wound etc.) on udder or teats or have suddenly dropped milk production. All samples were cultured on PPLO (pleuropneumonia like organism) media and were found negative for Mycoplasma spp. The prevalence of mycoplasma mastitis in this population of dairy buffaloes was recorded <0.23%. The study results suggested that the mycoplasma mastitis did not exist in buffaloes of study area, however, further studies using molecular tools are w...
Jocelín Selene Sánchez Cisneros1, Braulio Alejandro Fuantos Gámez1, Martin Herrik Ramón Kane1, Laura Miranda Contreras2, Camilo Romero Núñez2*
...skin, multiple folds and wounds. Skin samples were taken for histopathology and compared with a healthy specimen of the same species and colour characteristics. The diagnosis was cutaneous collagen dysplasia suggestive of cutaneous asthenia. This is the first report of cutaneous asthenia in a baby albino Burmese python in Latin America.
Keywords | Burmese python, Histopathology, Ehlers-Danlos syndrome, Wounds, Cutane...
Seun Eui Kim1,2*, Myoung-Hoon Lee1, Hye Myoung Jang2, Garam Park2, Wan-Taek Im3, Gwang Joo Jeon2,4*
... and 60 μM of CK, the wound coverage rates were 11.5% and 0.5%, indicating the cell migration was strongly inhibited. Among the apoptosis-related genes of BAK1, caspase -3, -8, -9, and -12, the expression of caspase 8 was decreased but the expression of caspase 9 and caspase 3 increased, suggesting that the intrinsic signaling pathway was highly activated. Throughout the analyses of cell cycle-related genes, CD1, CDK4, mTOR, Raptor, H-, K-, and N-Ras, the e...
Qi Zhuo, Yuanchun Yao, Meisongzhu Yang*, Jinhua Chen and Miao Tian
...n of cell proliferation; wound healing test and transwell assay were used to evaluate the ability of breast cancer cells to metastasize and invade; colony formation test was conducted to detect the effect of HDAC8 on the cells. We found that the expression of miR-216b-5p protein in breast cancer group was lower than that in healthy control group (P<0.05); the expression of HDAC8 protein in the group was higher than that in healthy control group (P<0.05)....
Dhiya Altememy1, Mohammad Darvishi2*, Samira Shokri3, Saber Abbaszadeh4
...ium alginate on infected wounds with Staphylococcus aureus was investigated in diabetic rats. Eight groups of 12 rats in any group were diabetic by intraperitoneal injection of alloxan. After the rats were anesthetized, 2cm2 wounds were created and inoculated with bacterial suspension of S. aureus (ATCC 12600) equivalent to the 0.5 MacFarland tube. The hydroalcoholic extracts of Origanum vulgare, Hypericum perforatum, and th...
Eighty Mardiyan Kurniawati1*, Budi Santoso1, Fedik Abdul Rantam2, Widjiati3, Budi Iman Santoso4, Tri Hastono Setyo Hadi1, Gatut Hardianto1, Hari Paraton1
...ot yet reached 100%. The wound healing process needs to be supported by certain ingredients such as regenerative medicine. Amnion is easy to find and rich in growth substances. Aim: This study analyzed the comparison of tissue structure in the remodeling phase of the vesicovaginal fistula between the use of freeze-dried amnion and primary suturing on day 21. Materials and Methods: This experimental study used New Zealand rabbits which were female and weighed 3...
Mohamed M. Bahr1, Mohamed S. Amer1*, Khaled Abo-EL-Sooud2, Shaimaa M. Kamel3, Marwa A. Fouly4, Ahmed N. Abdallah5, Ashraf A. Shamaa1, Omar S. El-Tookhy1
... ability to heal corneal wounds even if in the peripheral parts of the cornea that are deficient in limbal stem cells. Conclusion: In terms of safety, quality, regulatory concerns, and cost, EVs are superior to corneal transplantation and live stem cell therapy.
Keywords | Mesenchymal-stem-cell, Xeno-Exosomes, corneal-ulcer, histopathology, corneal-transplantation, AS-OCT, New-Zealand-rabbits, paracrine-signaling.
...
Falah Mahmood Hameed1*, Asaad Khalaf Talal AL-Shuwaili2, Eman Jawad Jabber3, Mayada Sahib Hassan1
...r was applied locally to wounds in group (A), as well as administered orally in group (B), and the wounds were left untreated in group (C) as a standard group. Each group was split into four subgroups, each consisting of two wounds, for histological analysis at the 0, 3, 7, and 14-day post-wound production and treatment durations. The findings showed tha...
Kazi Afsana Homayra Orchy1, Mst. Antora Akter1, Nelema Yesmin1, Md. Moshiur Rahman Khan1, Marzia Rahman2, Md. Mahmudul Alam1*
...ent of third-degree burn wounds. A total of 18 circular third-degree burn wounds measuring 10mm in diameter were made in six rabbits and studied under two groups: Group A and Group B. The wounds of Group A were treated topically with freshly prepared hPRP gel twice a week. The control rabbits received normal saline topically. The wounds were evaluated fo...
Reza Esmaealzade Dizaji1, Arasb Dabbagh Moghaddam1*, Arash Ghalyanchi Langeroudi2, Mohamad Foad Heydari3, Seyyed Javad Hosseini Shokouh4 and Ana Shirzad Shahrivar5
... on a second-degree heat wound and the healing process’ sub-streaming molecular route for re-epithelialization. Model (deep second-degree thermal wound), PRP, and PRP/BNF groups were each randomly assigned a set of animals. Wounds were monitored daily for many days following therapy to see how they were healing. H&E staining and qRT-PCR were used to examine the pathological alter...
Nida Sadaqat1, Sheheyar Ahmed Khan1, Amna Bibi1, Sadaf Zahra1, Muhammad faisal Salamt1, Noreen Latief2 and Fatima Ali1*
...proline was estimated in wound tissue. Wounded skin tissues were cut off and stored at − 20°C for PCR and ELISA analysis. The therapeutic effects of a NAC supplementation for a short period of time on rat skin wound healing were investigated. The NAC treatment promoted an improvement of wound healing by reducing the oxidative stress, imp...
Fatima Ali1*, Rimsha Tahir1 and Tahir Rehman Samiullah2
...used in the treatment of wound as dressing for the last thousands of years, however its effectiveness in clinical trials not yet been fully recognized. It is now known that honey acts as a biologic wound dressing with multiple bioactivities. Major aim of this study was to evaluate the efficacy of honey in combination with N-acetyl cysteine (NAC) for the treatment of excisional wounds in ra...
Aniqa Nasir1, Rashid Masih1, Shazma Massey1*, Laiba Arshad2, Sabi Ur Rehman2, Irva Waqar1 and Anwar Khalid3
... to prepare non-adherent wound dressing and its stability is determined by thermal analysis by using advanced isoconversional method. Isoconversional method is used to determine kinetic triplet including activation energy, pre-exponential factor and mechanism of thermal degradation. The prepared dressings were subjected to thermal analysis. Thermogravimetric analysis showed that the degradation of wound dressing occurs at 22...
Abdul Aziz1,2, Hamad Bin Rashid1*, Muhammad Arif Khan1, Asim Khalid Mahmood1, Ayesha Hassan1, Hamid Akbar1, Sadaf Imran1, Naveed Hussain1, Muhammad Umar1, Muhammad Asif1, Sajjad Javaid1 and Mamoona Chaudhry3
...d easy preparation. Burn wounds are a serious problem faced by veterinary clinicians in various animals. In this regard, the study was planned for the preparation and characterization of SVF from the adipose tissue of rabbits. Twelve healthy rabbits having body weight of 1000-1500g and of the same age were included in this study. SVF was prepared from bilateral inguinal fat that was harvested under general anesthesia. The harvested fat was enzymatically digest...
Johan Sukweenadhi1*, Stefan Pratama Chandra1, Finna Setiawan2, Christina Avanti2, Kartini Kartini2, Arief Koeswanto3 and Deok-Chun Yang4
...a very important role. A wound is an injury in which the skin is torn, cut, punctured, or traumatized. Wounds in diabetic patients are difficult to heal. Green synthesis is one of many methods that can be used to synthesize silver nanoparticles. Based on a statistical analysis of the average wound area, epidermal reconstruction, and TIME-H scores, significant differences began to occur fro...
Saddam Hummadi1, Nadia Al-Falahi2*
...
Treatment of infected wounds is one of the common challenges in veterinary practice. This study highlights the synthesis and use of hydrogel derived from small intestine submucosa (SIS) and AgNPs composite for accelerate the healing of infected wounds and improve cosmetic outcomes. A 5% w/v SIS hydrogel was prepared and formulated with 100 µg/ml AgNPs to evaluate its effect on healing of infected
Muhammad Talha Sajjad1, Hamid Akbar1*, Muhammad Arif Khan1, Muhammad Hassan Mushtaq3, Shehla Gul Bokhari1, Muhammad Abid Hayat4 and Ghulam Mustafa2
...l has been suggested for wound repair. However, there is insufficient evidence to support its usage in animals with cutaneous wounds. Therefore, this study aimed to evaluate the effect of PRP gel on cutaneous wound healing in rescued horses. Twelve horses were divided into two groups: group A (PRP-treated) and group B (control). The group A (n=6) animals were treated with autologous PRP ge...
Fazal Ur Rehman1*, Saeeda Fatehullah1, Ayaz Qadir1, Suleman Ahmad2, Siddique Usman2, Muhammad Asif2, Mukhtiar Ahmed1, Sunaina Rafi3, Muhammad Mohsin2, Ayesha Amanullah4, Faisal Shahzad2, Hasnain Raza2
...acs, urine incontinence, wound dehiscence and fistula formation was observed more in group A of open anal sacculectomy compared to group B of closed anal sacculectomy. It was concluded that closed technique is somewhat superior in post-surgical outcomes than open sacculectomy in terms of post-operative complications. ...
Wafa’a Mohammad Abduwhab1*, Waseem Ali Hasan2, Mohanad Abdulsataar AL-Bayati3*
...ext of third-degree burn wound healing. The reformulation of standard pumpkin seed oil involved the encapsulation of conventional Lidocaine within a phytosome structure, resulting in the formation of nanoparticles. This modification was undertaken to enhance both the physical stability of the oil and the therapeutic properties of pumpkin seed oil, while simultaneously mitigating the potential side effects associated with Lidocaine. Evaluation of the therapeuti...
Nabaa Fadhil Abbas*, Raffal A. Omar
...and remifentanil on burn wound healing in rabbits. The research involved 30 rabbits divided into five groups: G1 (Lidocaine), G2 (Tramadol), G3 (Remifentanil), and two groups that received combinations of remifentanil with epinephrine. Additionally, one group received remifentanil in a gel formulation. After local administration of these substances by infiltration (s/c) and compared with the control group. the severity of the burn injury and subsequent healing...
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