Shazia Ali, Hizb Ullah and Sarwat Jahan*
Kadir Karakuş1, Bahat Comba2, Abuzer Taş3, Tunahan Sancak3, Arzu Comba2, Devrim Saripinar Aksu4, Hasan Koyun5 and Mohammad Masood Tariq6,*
...al significance for TSH (thyroid stimulating hormone) were found as Surgical > Control > Formol (P <0.05). The order of statistical significance for growth hormone was Formol = Surgery > Control (P<0.05). In August month, the application factor was found to be significant only in testosterone (P <0.05). No significant difference between the control and surgical groups in testosterone was noted. In this study, although the application of diffe...
Muhammad Usman Saleem1, Saima Masood1,*, Hafsa Zaneb1, Aneela Zameer Durrani2, Asim Aslam3, Kamran Ashraf4, Habib-ur-Rehman5, Muti-ur-Rehman3 and Muhammad Shabir Shaheen6
... control group. Level of thyroid stimulating hormone (TSH) was increased significantly (p < 0.05) by the dietary treatments under study individually and in combination. It is concluded that supplementation of MOS and OAB in combination is beneficial compared to their individual effects in broiler chicks.
... 
Muhammad Amir Iqbal1, Nabila Roohi1*, Ahmad Qureshy2
...le induced by overt hyperthyroidism as well as its subclinical form. A total of 179 subjects comprising both genders and fulfiling the exclusion and inclusion criteria were recruited for this prospective investigation. Sixty healthy controls, thirty four subclinical, fifty overt hyperthyroid and thirty five follow-up subjects having 3 months of anti-thyroid therapy were recruited. Commerci...
Shaher Bano1, Sarah Ghafoor1,* and Nadia Naseem2
Jam Nazeer Ahmad1,2*,Mujahid Manzoor1, Zubair Aslam3 and Samina Jam Nazeer Ahmad1, 2
...uginous) against Parathyroid group of insecticide (Cypermethrin). Cytochrome P450 genes have been associated with insecticides resistance. Field collected population of R. ferruginous from different provinces of Pakistan was investigated for insecticides resistance development against P450 gene. Insect bioassay indicated highly significant level of LC50 values among laboratory reared and field collected population against Cypermethrin. The laborator...
Jie Yang
...-size: small;">Papillary thyroid cancer is one of the most common tumours subtype in thyroid cancers. Substantial amount of data have indicated that miR-16 is an important regulator of various tumours; however, the molecular functions of miR-16 in papillary thyroid cancer remained largely elusive. In order to investigate the regulation of miR-16, human papillary ...
Khayyam1*, Muhammad Zahid1, Naiz Ali2 and Qadeem Khan3
...ted after the autoimmune thyroid disease. Out of total eighty two autoimmune thyroid patients 50 were Hashimoto’s thyroiditis patients (HT) (30 female, mean age=34±1.43 years, 20 males mean age =38.35±1.17 years) and control group included 35 individuals (20 females mean age=31.65±1.77years, 15 males mean age=37.93±2.561 years). The 32 Grave’s diseas...
Q. Sun1, Q. Liu1, R. Di1, Y. Wang1, S. Gan2, S. Liu2, X. Wang1, W. Hu1, X. Cao1, Zh. Pan1, X. Guo1, Y. Yang3, H.E. Rushdi4* and M. Chu1*
Mohsin Ali1, Nargis Haider Kakar2, Rida Dawood3,4, Qurat-ul-ain Fatima5, Zunera Tanveer2, Shoaib Ahmad Malik6, Tauseef Muhammad Asmat1, Asadullah1, Muhammad Masood Tariq Kiani1 and Mohammad Zahid Mustafa1*
...mmune diseases including thyroid abnormalities. The current study, undertaken in collaboration with Shaikh Khalifa-Bin-Zayed Hospital Quetta, investigates the relation of thyroid abnormalities in 224 DM (both type 1 and type 2) patients. The parameters of age, duration of diabetes and type of treatment were measured. Venous blood was taken to investigate the thyroid profiles. Out of 224 pa...
A.M. Abdul Azeem, Ashraf M. Mounir and Amr N. El-Shahat*
...ration of insulin, total thyroid hormones triiodothyronin and thyroxine, leutinizing hormone, testosterone and testicular antioxidant parameters (glutathione content , the activity of xanthine dehydrogenase, superoxide dismutase and catalase) in the group of alloxan (150 mg/kg B.WT)-administrated rats as compared to control group. Treatment of diabetic rats with GPSDP (1 g/kg B.Wt/day/ 8 weeks) resulted in significant reduction of glucose level and lipid-perox...
Mohamed Abd El-Fattah Abo-Farw1, Maged Ahmed Aboul-Omran1, Abdel-Khalek El-Sayed Abdel-Khalek2*
...ate, antioxidant status, thyroid and reproductive hormones and trace elements such as Zn and Se.
Keywords | Mastitis, Buffaloes, Pregnancy rate, Antioxidant, Trace elements.
...
A. Samy1*, H.M.A. Hassan1, Fatma T.F. Abd-El Ghany2, Shama H. Morsy2
...y negative effect on the thyroid hormones with any treatments compared to the control. These results suggested that rabbits fed diets enriched with curcumin or garlic extract could have better performance, carcass characteristics, and antioxidant status compared to the control.
Keywords | Curcumin extract, Garlic extract, Growing rabbits, Antioxidant status, Productive performance and Thyroid hormone
...
Lin Lu
...de (HDP) on apoptosis of thyroid cancer cell line. TPC-1 cells were treated with HDP (final concentration 1 mg/mL, 2 mg/mL and 4 mg/mL), PI3K/AKT signal pathway inhibitor LY294002 (20 μmol/L) and LY294002 + HDP (4 mg/ml HDP and 20 μmol/L LY294002). Cell viability and apoptosis rate were detected by MTT and flow cytometry, respectively. The expression of Cyt-C, Bcl-2, Bax, cleaved Caspase-3, PI3K, AKT and p-AKT were detected by Western blotting. We found ...
Jabbar Khan1, Mehwish Jehan1, Zeeshan Mutahir2, Muhammad Rafi1, Muhammad Ismail1, Aamer Abbas1 and Jabbar Tanveer3
... in reduced synthesis of thyroid hormones. Beside that the concentrations of total protein, cholesterol, albumin and glucose were found significantly higher in Damani breed than control group, indicating that Damani breed had comparatively better adaptive capabilities in preparing the internal physiology and metabolic processes in response to heat-stress environmental conditions. Hence, vitamin E, in combination with Se improved the physiological and biochemic...
Noha M El-Motaily1, Ossama M Abdou1, Heba S Farag1, Kawkab A Ahmed2, Mahmoud Saber1*
... with lymphocytosis. Hypothyroidism demonstrated by reduced levels of free T4 and significant decrease in antioxidant trace elements level (Zn, Cu, Se).
Keywords | Antioxidant trace elements, Biochemistry, Canine demodicosis, Hematology, Histopathology
...
Hazem E. M. Hassanien1*, Awad M. M. Mahmoud2, Elsayed M. Abdel-Raouf1, Nabil M. Eweedah1 and Midhat. N. Nassif3
...h -100 and 0.0 DCAD. Parathyroid hormone was highest for 0.0 DCAD compared with -100, -180 DCAD. After calving there is a significant effect of tCa and iCa of prepartum treatment and we didn’t obtain any effect due to interaction between prepartum x postpartum treatment. Feeding an acidogenic diet improved Ca postpartum status....
Lei Xu1, Qin Yang2 and XiaoYan Zhang3,*
...osin, FGF-23, intact parathyroid hormone (iPTH), phosphorus, creatinine and uric acid, systolic blood pressure (SBP) and diastolic blood pressure (DBP) (P < 0.05), while the levels of 25(OH)D and calcium in serum and estimated glomerular filtration rate (eGFR) decreased (P < 0.05). Furthermore, the results of Pearson correlation analysis revealed that the level of sclerosin in serum was in positive correlation with age, serum phosphorus, iPTH, FGF-23, AA...
Midrar Ullah1, Nail Chand2, Abdul Kabir3, Muhammad Rasheed4, Hubdar Ali Kaleri5, Saqib Kakar5, Mubarak Ali4, Deepesh Kumar6, Asad Ali Shah1, Amir Shahb1, Muhammad Amir Khan1, Raza Ali Mangi7, Abdul Wahid Solangi5, Rameez Kaleri5,8*
...weight of goblet and TFT thyroid function test were performed. In this experiment total 9 hundred broiler chicks were purchased from local market and randomly divided into two groups 1 control and 1 irradiated. These groups were further distributed in two more replications with 50 birds per replication using the random treatment design. The findings our study showed that there was no significant influence of feed intake was recorded with irradiation. The resul...
Doaa H. Assar1, Rasha A. Al-Wakeel2, Zizy I. Elbialy3, Mahmoud M. El-Maghraby4, Helmy K. Zaghlool5, Adel A. El-Badawy4, Abdel-Khalek E. Abdel-Khalek6*
...teins, testosterone, and thyroid hormones (T3 and T4), and significantly decreased activity of aspartate and alanine transaminases (AST and ALT), triglycerides, cholesterol, low-density lipoproteins (LDL), very-LDL, and urea. Semen variables including semen volume, and percentages of sperm motility, livability, and abnormality as well as concentration and output of sperm cells were significantly by SPL. In serum and seminal plasma, glutathione, superoxide dism...
Anhar Ibrahim Elhanafy*, Amr Mohamed Mousa, Amaal Mohamed Kamal
...ty, oxidative stress and thyroid hormones in doe rabbits at high ambient temperature. Forty mature female New Zealand White rabbits (6 months age) were divided into four groups. Three of them (0.1, 0.2 and 0.3 mg/doe) represent different concentrations of BV, while the fourth group was control. Twice weekly injections of does were carried out along 12-weeks. Results revealed that BV treated does were significantly improved RBCs count, WBCs, serum total protein...
Yufang Liu1,2, Guiling Cao3, Yujing Xie3 and Mingxing Chu1*
... pathway, melanogenesis, thyroid hormone synthesis, and insulin secretion. Online tool was used to predict the function of DEGs, the results showed that the CYP11A1 gene might regulate the GDF9 and other prolificacy-associated markers in ovary organs of goats, thereby affecting the development of puberty. The expression of various genes and the transduction of hormone secretion signals, improving the reproduction of goats....
Selvaraj Thanga Malathi¹, Venkatraman Anuradha1*, Mohamed Yacoob Syed Ali2, Muhameed Sajjad Sarwar3, Nagarajan Yogananth2
...> hormones secreted from thyroid gland has vital role for all living organisms such as mammals, vertebrates etc., for their regular growth and development. The secretion of thyroid hormones may get disrupted in marine organisms due to environmental pollution. Heavy metal (chromium, beryllium etc.,) or trace metal (lithium, titanium etc.,) pollution alters the thyroid hormone secretion not ...
Feng-Yan Liu1,2,3, Ting Chen1,2,3, Yu-Hui Li1,2,3, Zheng Liu1,2,3, Jing-Jin Zheng1,2,3, You-Bang Li1,2,3* and Zhong-hao Huang1,2,3*
...ids (GCs), cortisol, and thyroid hormones (THs, T3 and T4) of rhesus macaques’ (Macaca mulatta) fecal pellet sampled from the Longhushan Nature Reserve, Southwest Guangxi, China. The results indicated that cortisol was negatively correlated with ambient temperature and sunlight, whereas T4 was positively correlated with sunlight. Cortisol levels sampled from spring/winter were higher than those sampled from summer/fall, while levels of GCs and T3/T4 were...
Abdullah Alsrhani1*, Aisha Farhana1, Shahid Hussain2 and Muhammad Ikram Ullah1
...tify;">Hashimoto’s thyroiditis (HT) is a chronic devastating autoimmune disorder of the thyroid gland, which develops due to environmental and genetic predispositions. Various studies have explored the role of 25(OH)-D deficiency in HT. Although vitamin D supplementation is suggested to improve thyroid functions, the mechanism of action of vitamin D on thyroi...
Aryaf Mahmood Sabea1*, Majida A. Al-Qaiym2
...owever the impact of hypothyroidism in immune cells and its relationship with selenium supplement in vivo has not well explored. Accordingly the present study designed to elucidate role of selenium in immunosuppression of hypothyroidism rats. Forty four female Wister rats of 3-4 months aged were equally and randomly divided into 5 groups except the control, which contains 8 rats. The 2nd, 3rd, 4th, and 5th groups were subjec...
MAH NOOR KHAN, NABILA ROOHI, BILAL JAVED & MUHAMMAD AMIR IQBAL*
...t-align: justify;">Serum thyroid hormone and TSH levels were determined in the worker of automobile workshops and petrol filling stations workers through ELISA. A total of 44 exposed individuals (25 automobile workshop and 19 petrol filling station workers) having an age range of 24-45 were recruited from Lahore city. Twenty one (21) healthy controls of the same age range were recruited from University of the Punjab, Lahore. A significant decline (P ≤ 0.05)...
Afshan1, Asad Ullah2*, Imad Khan2, Rafiq Ullah1, Tahira Tayyab1, Fatima Syed3, Raheela Taj3, Shumaila Gul4, Faiza Khan5, Ibad Ullah Jan6, Syed Weqas Ali7 and Assad Ullah8
... damage and imbalance of thyroid functions. The research experiment was performed to check the effect of orally inorganic selenium on the redox status and thyroid hormones of broilers under dexamethasone induce stress. Day old 100 chicks were purchased from trading hatchery and divided randomly into five different groups having four replicates (n=5) in each group. Broiler chickens feed with starter and finishing commercial c...
SYEDA NADIA AHMAD1, MEHWISH NASIR1, AQSA NAUREEN1, SHAGUFTA ANDLEEB4, KAUSAR RAEES3, TAHIR ABBAS2, ASMA YOUNIS1 & KHAWAJA RAEES AHMAD*1
... in each dose group) for thyroid and parathyroid histopathology. Tissues were recovered following 48 h of DZ treatment. Micrometric data in terms of follicular size of thyroid, cellular, nuclear sizes of the follicular and chief cells were obtained from the histological sections. Statistical analysis has shown significant (p<0.001) variations in mean follicular size of
ZAHRA NASEEM1, MUHAMMAD AMIR IQBAL1, SHAAF AHMAD2 & NABILA ROOHI1*
...justify;">Effects of hypothyroidism on liver and renal parameters and effectiveness of thyroid treatment (thyroxine) on these factors in hypothyroid subjects were assessed in the present investigation. A total of 140 subjects (30 subclinical and 50 overt hypothyroid) between the ages of 15-50 years from INMOL, Lahore and 60 healthy eu
Huda K. Khassaf1*, Zainab A.H. Al-Mousawi1, Sawsan A. Ali2, Anwar Nather Seiwan3
...amol (SAL) on many blood thyroid hormones and electrolytes. A total of forty rats, weighing between 200-250 g at the beginning, were divided into three experimental groups at random: the control group, the SAL group which was given (80 mg/kg) of SAL orally for two days, and SAL plus ALA groups which was given (80 mg/kg) of SAL orally for two days, followed by 20 mg/kg of oral ALA for 28 days. The levels of the hormones TSH, T4, free T3 and free T4 were estimat...
Marwa R. El-Deken1, Raouf E. Rizk1, Mona R. Ahmed1, Fouad A. Tawfeek1, Hossam A. Shahba1, Wesam A. Fares1, Ayman M. Khalifah2*
..., tibia bone quality and thyroid hormones.
Keywords | L-Glutamic acid, Layers, Egg production, Intestine, Bone quality
...
Amal Mohammed Ali Alah Al-Marmadhi*, Saadeya Ali lefelef Al-Gnami
...th induction of the hyperthyroidism. Fifty mature female rats (aged 90 days and weighted 150±10 g) have been randomly assigned to 5 equal groups (10 each),control (C) group , T1,T2,T3 and T4 groups were drenched with thyroxine (300mg/kg of B.W for 28 days ) for hyperthyroidism induction, T2 was drenched with methimazole (2.5 mg/kg of B.W for 30 days), T3 was drenched with allicin nanoparticles (50 mg/kg of B.W for 30 ...
Diyar Mohammad Hussein*, Iman Mousa Khaleel
...c characteristics of the thyroid and adrenal glands in suckling and adult local male cats. In suckling and adult cats, the thyroid gland was consisted of two entirely separated lobes without isthmus and appeared as smooth elongated oval shape with rounded cranial, narrow caudal ends and smooth lateral and medial surfaces. All measurements of left lobe in suckling and adult cats were higher than those of the right one. Statis...
Mohammed Haider Asker1*, Yahya Fawzi Hashim2, Huda Hamid Mohsen3
... markers (e.g. CRP), and thyroid function (e.g TSH) were assessed. Additionally, histological examination was performed post-H andE staining to for pathological lesions. The group G2 exhibited elevated levels of MDA (4.22 ± 0.16 mmol/L), CPK (317.40 ± 0.24 U/L), and troponin (1.19 ± 0.004 mg/dL), which collectively indicated oxidative stress and cardiac injury. In response to treatment with CoQ10, especially in groups G3 and G4, histopatho...
Saher Mahmood Jwad1, Tamadhur Hani Hussein2, Tahreer Mohammed Al-Thuwaini2*
...act on the regression of thyroid and hepatic tissues, as well as on oxidative stress markers induced by paracetamol (acetaminophen), a study was conducted on sixty male laboratory rats. The animals were equally divided into four experimental groups. The control group was orally treated with 0.9% normal saline solution. The second group was orally administered 1g/kg of paracetamol. The third study group was orally given 200 mg/kg of broccoli aqueous extract alo...
Tamadhur H. Hussein1, Zainab M.A. Alrubayei2, Tahreer M. Al-Thuwaini1*
...ext-align: justify;">The thyroid gland in sheep plays a vital role in reproduction by regulating the secretion of reproductive hormones in the hypothalamus, which influences gonadotropin neurons. This study aimed to determine whether thyroid hormones are associated with litter size. A total of 100 healthy, sexually mature ewes, aged 3 to 4 years, participated in the research. The ewes were divided into three groups: non-preg...
Zainab Sadik Chetheer*, Aseel Abdullah Ibraheem
... somnifera supplement on thyroid hormones of males rabbits induced hypothyroidism by propylthiouracil (PTU). Twenty-four rabbits were divided into four groups: the first group received tap water only (control group), the second group received Withania somnifera supplement at a dose of 500 mg/kg B.W., while the third group received PTU at a dose of 100 mg/kg B.W. and finally the forth group T2 was received both PTU and Withan...
N. M. Abed
... chloride (NiCl2) alters thyroid hormones and causes morphophysiological changes and oxidative stress. Reactive free radicals from carbon tetrachloride (CCl4) damage the liver and kidneys. On the other hand, propolis has antioxidant, anti-inflammatory, anti-cancer, antibacterial and hepatoprotective properties. Propolis protects thyroid and gonadal function from NiCl2 and CCl4. In order to assess the protective impact of pro...
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