Thyroid Dysfunction and Prevelance of Both Clinical and Subclinical Form of Hypothyroidism and Hyperthyroidism in District Swabi, Khyber Pakhtunkhwa, Pakistan
Thyroid Dysfunction and Prevelance of Both Clinical and Subclinical Form of Hypothyroidism and Hyperthyroidism in District Swabi, Khyber Pakhtunkhwa, Pakistan
Madeeha1, Mehreen Riaz2* and Abdul Wahab3
ABSTRACT
Thyroid dysfunction is one of the most prevalent endocrine abnormalities, varies with age and gender. The study objective is to find thyroid dysfunction and the occurrence of clinical and subclinical hypothyroidism and hyperthyroidism in people of district Swabi, Khyber Pakhtunkhwa, Pakistan. Blood samples were taken from 104 people, and information was gathered via questionnaire. CLIA kit, Auto Bio Diagnostics LTD, China was used to detect TSH, T3, and T4 quantitatively by using Chemiluminescence Immunoassay (CLIA). Out of 104 individuals, 64 were females and 40 were males. A total of 24 people (23.04%) were affected by thyroid dysfunction, with 7 (17.5%) men and 17 (26.5%) women suffering from clinical and subclinical forms of hypothyroidism and hyperthyroidism, respectively. The occurrence of subclinical hypothyroidism was found to be the highest, with 10 cases (9.6%) recorded, followed by subclinical hyperthyroidism with 7 cases (6.7%), clinical hyperthyroidism with 4 cases (3.84%), and clinical hypothyroidism with 3 cases (2.9%). The study also revealed that the highest incidence of thyroid dysfunction occurred among individuals aged 31-40, with 6.73% affected, followed by those aged 41-50, with 5.8% affected. To conclude the women were more probable than men to have thyroid dysfunction in the area of District Swabi, and older people were more probable to have it than younger people. Iodine deficiency is the most typical cause, whereas in females, breastfeeding and pregnancy were the typical reasons.
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