Sehrish Kanwal1, Ali Saeed1*, Muhammad Munir2, Memoona Arshad1
British Journal of Virology
Xingdong Yang and Lijuan Yuan
...s and humans in terms of genetics, physiology, intestinal anatomy, and immune system, pig is particularly a suitable animal species for the modeling of human enteric pathogen infections, immune responses and for vaccine evaluations. These are the basis for the successful establishment of the infection and disease models for human rotavirus, human norovirus and human enterovirus 71 using neonatal gnotobiotic pigs. The differences between germ-free and normal an...
Ummara Waheed Khan, Raza Ahmed, Irum Shahzadi and Mohmmad Maroof Shah
Email | [email protected]
...e discovery of molecular genetics and biotechnological techniques, such as genome mapping, tissue culture, genetic transformation and in vitro regeneration offered new dimensions of research to improve important crop species including wheat. The tissue culture by itself has increased the crop improvement potential to develop new cultivars with desirable traits through somaclonal and gametoclonal selection. While successful tissue culture is...
Tauseef Taj Kiani1*, Mozammil Hussain1 and Hidayat ur Rahman2
...actical contributions of genetics to the agricultural world and has its most signi cant expression in maize than other cereal crops. Exploitation of this phenom- enon of superior performance of F1 progeny over their parents not only trans gured maize breeding schemes but also constituted the foundation of maize seed industry. Evaluation of per se performance of parental lines and estimation of heterosis and inbreeding depression are prerequisites to start hybr...
Ashley C. Banyard1* and Satya Parida2
...with both viral and host genetics being thought to influence the outcome of disease. Following the successful global eradication of rinderpest virus, peste des petits ruminants virus has also been targeted for global eradication by the OIE. Whilst the tools are available to attempt eradication there are a number of factors that will influence the strategy taken to progress with the aim of eradication. Here we describe current areas where knowledge ...
Amitha Reena Gomes1, Belamaranahally Muniveerappa Veeregowda2, Sonnahallipura Munivenkatappa Byregowda1, Vinayagamurthy Balamurugan3*
...es and peptides, reverse genetics, anti idiotypic antibody based vaccines and helper cell dependent diagnostics represent the present vaccine/diagnostic development strategies for the effective control and eradication of PPR. This review comprehend the current scenario of recombinant technology based vaccines and diagnostics, virus like particles (VLPs), reverse genetics approach etc., in the development of diagnostics and v...
Waqar Islam*1, 2, Madiha Zaynab3, Muhammad Qasim2 and Zujian Wu1,2
... involving cis and trans genetics. The review adhere recent research findings regarding disease resistance against viral diseases and concludes via shedding light upon the future prospects in this exciting field of research.
... 
Tianzhu Chao, Huiqiang Cai, Yuxun Zhou, Kai Li* and Junhua Xiao
...gated the molecular phylogenetics of Chinese house mice based on 466 DNA sequences from mitochondrial D-loop fragments. Our analyses revealed that Mus musculus musculus and M. m. castaneus are older colonized subspecies with broad distributions in East China, while M. m. domestics is a newly arrived subspecies currently restricted to Shanghai, indicating the elevated risk in this cosmopolitan cities. Phylogenetic analysis indicates that
Urooj Fatima1, Arslan Mehboob2, Muhammad Abid3, Muti-ur-rehman Khan4 and Tahir Yaqub4*
...he current situation and genetics of CPVs in Pakistan, a total of fifty samples from sick dogs suspected for parvovirus infection were collected from different geographic areas of the country. Samples were screened for positivity and verified for CPV using PCR. From a 30% positive samples for hemagglutination, nineteen (38.4%) samples were positive in PCR. Sequence analysis of the selected positive samples revealed that both CPV-2 and new CPV-2a strains are ci...
Madiha Hashmi1, Abid Hussain1, Shafiq ur Rehman1, Farida Ahmed2, Shahbaz Aslam3,Nadeem Afzal4 and Zaigham Abbas1,*
Muhammad Imran Shabbir
...;">The heart of learning genetics is in realizing that how the likelihood of inheriting a particular trait can be predicted. This fundamental approach is the basis for plant and animal breeding to get desired varieties as well as performing genetic analysis including prediction of patterns of inheritance in family lines and to calculate the recurrence risk for relatives etc. Punnett square is used to describe the possible combinations of paternal and maternal ...
Sher Nawab Khan* and Ghulam Hassan
Zihong Chen1, Ling Xu2, Xiaona Yang2, Yaguan Zhang3* and Yuming Yang4
...ed with a multigene phylogenetics analysis involving 5.8S–ITS, nrSSU, nrLSU, EF–1α, RPB1 and RPB2. In multilocus phylogeny, M. baoshanense was grouped as a sister clade to Metarhizium majus, Metarhizium guizhouense, Metarhizium lepidiotae and Metarhizium indigoticum, but conclusively separated from these allied species with high support value. Morphological character differentiated M. baoshanense from...
Yasir Ali1*, Muhammad Aslam Khan1, Muhammad Atiq1 and Muhammad Hussain2
...gist, plant breeders and genetics to develop non-specific rust resistant wheat varieties through gene pyramiding or marker assisted breeding ...
Yuan Li1, Liyan Zhang2, Karhoe Loh3, Ji Feng1, Xinqing Zheng1, Puqing Song1 and Longshan Lin1,*
...tudies on the population genetics of P. minor are not yet available. In the present study, the mitochondrial Cytb gene was employed to investigate the population genetics of P. minor collected along the coasts of China and Malaysia. The genetic diversity of all P. minor populations was moderate, and two major haplotype lineages were detected that were differentiated approximately 0.3 million years ago. T...
Muhammad Arshad*, Sabeeta Jan, Sundas Awan, Samra Azam, Shiguftah Khalid and Muahmmad Ayub Khan
Liyan Zhang1,2, Zhidong Zhou1,3, Haiping Li1,2, Yanlong Qiao4, 5 and Yueping Zhang1,3,*
... evaluate the population genetics and elaborate the historical demography of Scomber japonicus collected from four geographical locations in the Taiwan Strait and its adjacent waters. The results of genetic diversity and genetic structure analysis of S. japonicus showed that these four populations exhibited moderate genetic diversity across the sampled geographical range of the species. However, no phylogenetic structure corresponding to geograph...
Iram Maqsood1,2,3 and Ke Rong *1,2
...racteristics, population genetics, and organ preservation. In addition to this, the habitat restoration program committed to improving the quality and habitat area. The reintroduction project illustrated that A. Sinensis bred in captivity well adapted to wild habitat and successfully reproducing their offspring’s. Only healthy crocodiles were selected for release into the wild to renew natural populations. Chinese alligator currently under strict ...
Bingbing Gao1, Na Song1, Zhonglu Li2, Tianxiang Gao3 and Liqin Liu3,*
...ns.
...
Hong Ma*, Bo Fu, Liang Wang, Zhong-qiu Li and Di Liu*
...nd can be modified by epigenetics. However, whether HSPC117 affects development of cloned embryos mRNA expression is unknown. To investigate the influences of HSPC117 on embryonic development, we generated transgenic porcine embryos by handmade cloning. We then assessed the embryonic developmental rate at cleavage and blastocyst stages. Our results showed that the HSPC117 transgenic embryos had markedly higher cleavage and blastocyst rates...
Hafiza Sadaf Zahra1, Asia Iqbal2, Sayyeda Hira Hassan1, Hafiz Abdullah Shakir1*, Muhammad Khan1*, Muhammad Irfan3, Chaman Ara1, Shaukat Ali4
Basharat Hussain Shah*, Farrukh Siyar Hamid, Shams ul Islam, Naveed Ahmed, Fayaz Ahmad, Noorullah Khan and Qamar uz Zaman.
Ajmalud Din1*, Munir Ahmad2, Fahad Masoud Watto2, Sheraz Ahmed1, Imtiaz Ali1 and Muhammad Kausar Nawaz Shah2
Muhammad Ilyas1, Sardar Ali Khan1, Shahid Iqbal Awan1, Shafiq-ur-Rehman1, Waqar Ahmed1, Muhammad Riaz Khan2, Raja Mohib Muazzam Naz2, Muhammad Mohib Ullah Khan3 and Sumaira Hafeez1*
Muhammad Rizwan Ashraf1, Asif Nadeem1,2, Eric Nelson Smith3, Maryam Javed1, Utpal Smart3, Tahir Yaqub4, Abu Saeed Hashmi1 and Panupong Thammachoti3
Muhammad Umer Khan1,2*, Muhammad Farooq Sabar1, Atif Amin Baig3, Arif-un-Nisa Naqvi4 and Muhammad Usman Ghani1
...s can benefit population genetics and forensic sciences. Consequently, this study was designed to establish the mtDNA profiles of the Shin ethnic group in Gilgit-Baltistan, the northern most territory of Pakistan. Phlebotomy was performed for a total of 79 maternally unrelated Shin volunteers. Genomic DNA was extracted from whole blood samples and subjected to PCR amplification using specific primers for the control region of mtDNA (covering positions 16024&nd...
Tanveer Hussain, Masroor Ellahi Babar*, Akhtar Ali and Fiaz Hussain
...n efforts to explore the genetics of the camel, we chose to study the Inteferon beta 1 (IFNβ1) gene in in Mareecha camel and non-descript camel breeds in Pakistan. We amplified the IFNβ1 gene through PCR, followed by sequencing. All sequences were aligned and edited through Codon Code aligner and finally a 364 bp portion was selected for further analysis. Dual peaks/heterozygous conditions were identified at positions c.36 (A/C), c.87 and c.225 (Y, T...
Samaria Nisar1, Tariq Manzoor Khan1, Muhammad Ahsan Iqbal1, Rahmat Ullah2, Muhammad Asim Bhutta3*, Saghir Ahmad3, Amna Bibi3, Hafeez ur Rehman4, Umar Farooq4 and Muhammad Zubair Ishaq5
Jiao Ma*
...otype, cardiac stem cell genetics and their ability to treat heart injury have been studied. Understanding the molecular processes and messaging pathways involved in success Cardiac stem cells offer an effective approach to the production and presentation of cardiac lesion therapy using cardiac stem cells....
Saydat Saad1, Doaa Abdel-Fattah1, Tarek Khamis2, Aya El-Sobky1*
...inary physiology, animal genetics, and reproduction. Nano-propolis is beneficial to veterinary medicine in different aspects by varying the size of propolis using various techniques, nano-propolis can be more effective without compromising its qualities. Propolis has numerous benefits, including anti-inflammatory, antioxidant, anticancer, and antifungal properties. Low bioavailability, solubility, absorption, and untargeted control, the advantages of free form...
Shakila Mumtaz1, Khalid Javed1, Muhammad Dawood1*, Muhammad Imran2, Asad Ali1 and Nazia Ramzan1
...ely on the breed’s genetics and ration fed. Different proteins can be found in milk. Beta-caseins are thought to be more important because some serious health-related issues in humans have been reported with the consumption of A1 milk (mutated casein variant). This study was planned to investigate the polymorphism in the beta-casein gene (CSN2) in Sahiwal (40), American Holstein Friesian (40) and the crossbred (Sahiwal × HF) (50). PCR-RFLP and conf...
Ali Basim Abd Al-Hadi*, Tahreer Mohammed Al-Thuwaini, Mohammed Baqur Sahib Al-Shuhaib
...tion rate, hormones, and genetics. Genetics and endocrine signal transpositions between the pituitary and the ovary play a crucial role in the reproductive traits of sheep. Genetic polymorphism of candidate genes is associated with economic traits. Follistatin (FST) gene is one of the most notable potential candidate genes linked to economic traits. This study aimed to assess the genetic variation of the FST gene and reprodu...
Emel Hulya Yukseloglu1, Fatma Cavus Yonar1*, Omer Karatas1, Gulten Rayimoglu1, Faruk Asicioglu1, Elif Canpolat1, Onur Ozturk2 and Itir Erkan3
...arameters and population genetics data were calculated by using Arlequin v 3.5.2.2 version. According to our results, SE33 (PM=0.014) locus showed the greatest power of discrimination and TPOX (PM=0.132) has the least power of discrimination power in Turkish population. Combined power of exclusion and combined power of discrimination were calculated as 99.99999963% and 99.99999999%, respectively. In addition, allelic frequencies from our study were compared to...
Abdurakhim E. Kuchboev1*, Mehmonjon Kh. Egamberdiyev2
...hotypes. After molecular genetics and morphological analyzes, these land molluscs belonged to 8 different species: Angiomphallia regeliana, Pseudonapaeus albiplicatus, P.maydanica, P. sogdiana, Psedonopaeus sp., Xeropicta candacharica, Deroceras reticulatum and Candaharia levanderi. The infection rate of Pulmonata snails by protostrongilids larvae was 28.2% and that of slugs - 6.8%. In addition, the first informs of P. maydanica, C. levanderi and D. reticulatu...
Shafia Riaz1, Khalid Abbas1*, Tanveer Ahmed1,2*, Huma Naz3, Hina Amjad1 and Shahbaz Ahmad1
Mishal Bano1, Amir Shakeel1, Waqar-ul-Haq1, Muhammad Nouman Khalid1*, Nadia Hussain Ahmad2, Muhammad Sajid Sharif3, Sadia Kanwal2, Muhammad Asim Bhutta2, Amna Bibi2 and Ifrah Amjad1
Xiaoying Liang1,2, Xiaofang Jiang3, Honglin Jia1, Ru Zhang1, Li Gao4* and Qing Yang5*
...nflammatory response. Epigenetics has an impact on disease occurrence. Epigenetic regulation in T cells contributes to the development of experimental asthma, which can be treated pharmacologically....
Zhao Fulin1,2, Liang Chen2, Tao Lin1, Jiang Yanting3, Ouyang Yina3, Hong Qionghua3* and Chu Mingxing1*
...ferent goats. Population genetics statistics showed that FGFR1 gene g. 12120297A> G and EPB41L5 gene g. 64237881A> C were low polymorphisms in the three populations (PIC< 0.25); EPB41L5 gene g. 64266710G> C and g. 64266715G> C were moderately polymorphic in Yunshang Black goat and Liaoning Cashmere goat (0.25<PIC<0.5), and in Jining Grey goat was low polymorphism (PIC< 0.25). The χ2 test indicated that EPB41L5 gene g. 64237881A> ...
Yanping Li, Fei Xu, Yongming Wang*, Yunyun Lv, Jinrong Shi, Biwen Xie, Wenyao Cai and Dian Liu
...rvation and conservation genetics of these two loaches....
Muhammad Salman Ikram1, Tahir Mehmood1,2*, Sehrish Firyal3, Huma Sattar4, Shagufta Saeed3, Fareeha Nadeem3 and Muhammad Imran Mahmood Khan5
...d technology in forensic genetics. This manuscript also demonstrates the unique features of Y-STR markers and their different application in forensic like significance of population genetics and genealogical pattern of Y-chromosome STRs diversity in different regions of world which helps to understand the pattern of variation in DNA within and between species, importance of Y-STR in relation of its haplotype diversity and fr...
Yingying Ye1, Chengrui Yan1, Kaida Xu2, Jiji Li1, Jing Miao1, Zhenming Lü1 and Baoying Guo1*
Arnold Christian Tabun*, Ferdinan Suharjono Suek, Cardial L Leo Penu, Johanis A. Jermias, Thomas Lapenangga
Muhammad Mukhtar*, Syamsul Bahri, Syahruddin
Chengrui Yan1, Jing Miao1, Jiantong Feng1, Liping Xia1, Yingying Ye1,2*, Jiji Li1 and Baoying Guo1,2
...ene. Analysis of the COI genetics indicated a high level of genetic diversity among T. clavigera. Our analysis of population genetic and demographic (AMOVA, haplotype networks and mismatch distribution) revealed a single genealogical branch and indicated undifferentiation of T. clavigera in the China Sea. Migration dynamic analysis showed that gene flow was asymmetrical and QD as the source population. Additional, canonical correspondence analysis (CCA) analys...
Yasameen Waleed Al-Abedi1, Murtadha Kadhim Hasan2*, Alaa Abdalhadi Halboti3, Ali Abdulhussein Saleh Alsaeedi3, Rafed Abbas Kadhum1
...al cases for modified epigenetics through CRISPR-Cas integration in biological engineering and medicine. Therefore, it enriches the body of knowledge concerning the application of CRISPR-Cas in valuable discoveries in biotechnology and medicine....
K.M. Siddiqui and M. Saleem Khattak
...on is useful in forest genetics and tree improvement work. Pollen flow within a tree population determines its mating pattern and consequently local and geographic variation in the species. Studies carried out in the past have shown that pollen and seed travel relatively short distances and gene flow is limited enough to promote genetic differentiation (Wright, 1953, 1962; Strand, 1967; Sluder, 1969). On the other hand, though it impli...
Xiaoping Gao1, Yanping Li2*, Renyi Zhang3, Yunyun Lv2, Yongming Wang2, Jinrong Shi2, Jiang Xie2, Chiping Kong1 and Lekang Li1
...cive to the conservation genetics and cave adaptation for S. cyphotergous....
Shiguftah Khalid1, Muhammad Jahanzaib2*, Haris Khurshid2, Rabia Khalid3, Sundas Waqar3, Faiza Siddique3, Fazal Yazdan Saleem Marwat3 and Zahid Akram1
Yasser Asaad Hameed Al-Shareef, Firas Hussain Kadim Abawi*
...aken together, clinical, genetics and molecular biological approaches identified velogenic strains of NDV in poultry which breach the immunity induced by the currently applied vaccines, warranting future monitoring to better device control strategies in poultry. ...
