Sanjukta Chakrabarti1, Colin J. Barrow2, Rupinder K. Kanwar3, Venkata Ramana1*, Rakesh N. Veedu4,5 and Jagat R. Kanwar3*
...lign: justify;">Abnormal angiogenesis or the formation of aberrant vasculature in humans, may lead to various pathological conditions including tumor development. The most important factor implicated in the angiogenic processes is vascular endothelial growth factor (VEGF) protein and its family of ligands and receptors (VEGFRs). Survival, proliferation, migration and invasion of endothelial cells which give rise to the vascular network, is mediated through VEG...
Ayesha Noreen1, Dilara A. Bukhari2 and Abdul Rehman1,*
...tion, invasion, inducing angiogenesis, inflammation and cellular transformation in cancer. A better understanding into the mechanism of ROS in cancer progression might be useful for the development of biomarkers and therapeutic strategies. The objective of this review was to summarize the roles of ROS in different stages of cancer, cell invasion, angiogenesis and metastasis.
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Fang Liu*
...n dependent functions in angiogenesis and hypothalamic axon guidance. At lower concentration of 100ng/ml, FGF10 promotes angiogenesis in chorioallantoic membrane endothelial capillaries (CAMs), but FGF10 does not alter the endothelial growth significantly at higher concentration (500ng/ml, P>0.05). Simultaneously, FGF10 exerts a graded action, at lower concentration FGF10 attracts both magnocellular and parvocellular axon...
MA Liman1, QI Yongxiao1, Wang Wenji2* and Zhong Qianyi3*
...rmal organism. Excessive angiogenesis can have detrimental consequences in various processes, including promoting uncontrolled tumor growth. Inhibiting angiogenesis using natural compounds is an important focus in developing new cancer treatment strategies. Ginsenoside Rh2 (G-Rh2), a natural product derived from red ginseng, has been reported to have therapeutic effects on some tumors, but its antiangiogenic effects in zebra...
Seun Eui Kim1,2*, Myoung-Hoon Lee1, Hye Myoung Jang2, Garam Park2, Wan-Taek Im3, Gwang Joo Jeon2,4*
...ivity. The expression of angiogenesis-related gene of VEGF unexpectedly was increased. In conclusion, this study confirmed that ginsenoside CK is a new anticancer candidate with excellent anticancer activity inducing cell cycle arrest, apoptosis and in some extent cell migration/metastasis inhibition for neuroblastoma.
Keywords | Neuroblastoma, Compound K , Anticancer
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Dhiya Altememy1, Mohammad Darvishi2*, Samira Shokri3, Saber Abbaszadeh4
...(H&E) of the tissue, angiogenesis rate, and division of fibroblast cells and Masson’s trichrome slides were used to determine the rate of collagenization, wound, and extracellular matrix. After the treatment, the size of the wound in the Tio2 N.P. synthesis by Origanum vulgare, Tio2 N.P. synthesis by carvacrol, methicillin, Tio2 N.P., and alginate pad groups of diabetic rats and alginate pad group of non-diabetic rats were determined 7.03 ± 1,...
Xiajun Zhang1, Jie Yang2, Wenjun Zhou1, Zhenshi Chen2, Weidong Wu3, Shaoru Zhang2 and Lihui Wang2*
...ates cell proliferation, angiogenesis and metastasis, and is an inducer of epithelial-mesenchymal transformation. Tumor cells activate the TGF-β/Smad pathway, and inhibiting its signal transduction pathway is an important strategy for tumor therapy. First, we have found lncRNA CASC7 is a poor prognostic marker of endometrial cancer. Then, ASPN was specifically expressed in endometrium and cell specific expression in basophils, among the most similar genes...
Eighty Mardiyan Kurniawati1*, Budi Santoso1, Fedik Abdul Rantam2, Widjiati3, Budi Iman Santoso4, Tri Hastono Setyo Hadi1, Gatut Hardianto1, Hari Paraton1
...on included fibroplasia, angiogenesis, re-epithelialization, and collagen deposition on day 21. Data were analyzed descriptively and statistically. Results: The mean scores of angiogenesis, fibroplasia, re-epithelialization, and collagen deposition in a New Zealand rabbit model of vesicovaginal fistula sutured with human amniotic stem cell seeding were higher than rabbits without amniotic stem cell seeding, the stem cell inj...
Dalia Zaafar1*, Heba M.A Khalil2, Soha Hassanin3, Mohamed R. Mousa4, Mona G. Khalil1
...t cell proliferation and angiogenesis. Six groups were created using sixty male mice after the Ehrlich inoculation tumor growth was confirmed: control, Cis (5 ml/kg), Pio low dose (LD) (17.5 mg/kg), Pio high dose (HD) (30 mg/kg), Cis+Pio LD, and Cis+Pio HD. Different parameters, including behavioral, biochemical such as malondialdehyde (MDA), reduced glutathione, superoxide dismutase (SOD), tumor growth factors, and apoptotic TUNEL assay, were evaluated after ...
Falah Mahmood Hameed1*, Asaad Khalaf Talal AL-Shuwaili2, Eman Jawad Jabber3, Mayada Sahib Hassan1
...cellularity and expanded angiogenesis compared to non-treated group. Conclusion: The histological results supported the hypothesis that chitosan enhances and promotes the development of wound healing on the skin. ...
Fatima Ali1*, Rimsha Tahir1 and Tahir Rehman Samiullah2
...o confirmed by analyzing angiogenesis, apoptosis and chemotaxis genes. A significant increase was observed in the percentage of wound contraction and significant decrease in the period of epithelialization in honey+3% NAC group as compared with control group. Histologically, honey+3% NAC Group treatment resulted in almost complete re-epithelialization and re-structuring of the wound tissue. There was a significant rise in catalase and decrease in GSH levels in...
Ahmed Kadhim Munahi1* , Hameed A. Al-Timmemi2
...n grey matter, increased angiogenesis, and minimal scar tissue formation at the injured spinal cord site. In conclusion and based on clinical and histological data, chitosan nanoparticles could accelerate and promote regeneration of the injured spinal cord. ...
Bunga Rimta Barus1, Masfria Masfria2*, Aminah Dalimunthe3, Sovia Lenny4
...n; 1.34 nm) and promoted angiogenesis (26.33 ± 0.31) in the wound area. These results indicate that the 5% ethyl acetate fraction gel is the most effective in promoting wound healing by enhancing both epidermal regeneration and angiogenesis.
Keywords | Antibacterial, Ethyl acetate, Fraction, Gel, Staphylococcus aureus, Wound
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