Articles

Green Synthesis, Characterization, and In-Vitro Anthelmintic Activity of Propolis-Chitosan Nanoparticles Using an Earthworm Model

Sunday Onyebuchi Ukanwa

Helminth infections remain a major global health problem, particularly in developing countries, and resistance to conventional anthelmintic drugs is increasing. The present study aimed to develop and evaluate nanoparticles synthesized from natural products for…

Antibiotic Susceptibility Profiles and Resistance Genotypes of Non-Typhoid Salmonella Isolates from Live Chickens in Dar es Salaam, Tanzania

Tumwi Tumwene Salah, Paulo Stephen Joseph, Godwin Andrew Minga, Bishop Ignus Magidanga, Richard Simon Mwakapuja, Victor Makene

Multi drug resistance of non-typhoid Salmonella spp. is on the rise worldwide. The current study was conducted to determine the antimicrobial suspectability profiles and resistance genotypes of non-typhoid Salmonella (NTS) in live chicken in Dar es Salaam, Tan…

Harnessing Microalgae for the Bioremediation of Microplastic Pollution in Marine Ecosystems

Tuba Arooj, Itrat Zahra, Awais Ibrahim, Ayesha Liaqat, Roohi Ijaz, Naveed Ahmad et al.

Marine microplastic (MP) pollution is an escalating environmental crisis, with trillions of plastic particles accumulating across oceanic ecosystems. Conventional remediation strategies offer limited effectiveness against MPs, especially under real-world marin…

Investigating Plant Extracted Novel Phytoactive Compounds as Estrogen Receptor Inhibitor

Aneesa Anwar1#, Aisha Jamshed1#, Ayesha Qasim, Mouzma Amjad, Qurban Ali, Erum Zafar et al.

Breast cancer remains a major cause of mortality among women globally, underscoring the continuous need for more efficacious and safer drugs. The structural diversities as well as biological activities of phytochemicals and marine-derived natural products rend…

Levels of Alkaline Phosphatase, Erythrocyte Sedimentation Rate, and C-Reactive Protein in Rheumatoid Arthritis Individuals

Raazia Tasadduq, Hamna Safdar, Iqra Baig, Nabia Arif, Fatima Farhan

Rheumatoid Arthritis (RA) is a chronic autoimmune polyarticular disorder characterized by inflammation of joints leading to systemic complications. Early detection of rheumatoid arthritis is difficult to achieve due to a variety of reasons. The present study w…

Combined Issue, Number 1, 2026

Repositioning of FDA Approved Nsaids for Potential STAT3 Inhibitors: A Molecular Docking Study

Zainab Ahsan, Erum Zafar, Ayesha Qasim, Aisha Jamshed, Mouzma Amjad, Muhammad Khan

Signal transducer and activator of transcription 3 is a latent transcription factor involved in various cellular processes, cell proliferation, apoptosis, inflammation, immunity, angiogenesis, and metastasis. Controlled regulation of STAT3 activity is maintain…

Cloning and Characterization of a Novel cry2Ad5-Type Gene from HD29 Strain of Bacillus thuringiensis subsp. galleriae

Faiza Saleem, Munawar Saleem Ahmad, Abdul Rauf Shakoori

Bacillus thuringiensis subsp. galleriae HD29 (Bacillus Genetic Stock Center ID 4G5; Serotype 5a5b) is known to harbor multiple Cry-type genes such as cry1Cb, cry1Db, cry1Ga, cry2Ab, cry2Ac, cry9A and cry9B, which produce crystals consisting of 65- and 130-kDa…

Prevalence of MDR and XDR in Clinically Relevant Enterobacteriaceae from Local Food Samples

Ifrah Amjad Naseer, Eeman Ali, Dilara Abbas Bukhari, Abdul Rehman

In this study, Enterobacteriaceae were isolated from food samples, either in raw or cooked form, including some bakery items, meat, fruits, vegetables, and sweets. This study aimed to obtain multidrug (MDR) and extremely drug-resistant (XDR) bacteria that have…

Effect of High Fat Diet on Liver Steatosis and Renal Function of Male and Female Wistar Rat

Sibgha Mumtaz, Kainat Malik, Arif Ullah, Abbas Khan, Abdul Rehman, Dilara Abbas Bukhari

Nonalcoholic fatty liver disease (NAFLD) and chronic kidney disease (CKD) are the most common forms of liver and kidney disorders, respectively, characterized by the excessive accumulation of fat. This study aimed to establish a rat model for NAFLD with steato…

Epidemiology-Pathogenesis-Management-of-Preeclam

Muhammad Shahid Nadeem, Saima Iftikhar, Bibi Nazia Murtaza, Inam Ullah, Iram Sarwar, Mahnoor Murtaza et al.

Preeclampsia (PE) is a pregnancy associated complication mainly demonstrated by the onset hypertension, proteinuria, foetal growth restriction, and maternal organ dysfunction including renal, cerebral and hepatic diseases before or after 34 weeks of gestation.…