Faiza Hassan1, Mubshara Saadia1,*, Muhammad Sher1, Mian Anjum Murtaza2, Muhammad Arshad3,Asam Riaz4 and Mahmood Ahmad Khan5
...to evaluate the relative antidiabetic potential of garlic aqueous (AGE) and petroleum ether (EGE) extracts compared to black cumin (Nigella sativa oil; NSO) and insulin. Alloxan induced diabetic rats were post treated with plant extracts (150 mg/kg) and serum samples were collected from overnight fasted diabetic rats on day 15 to observe thepercent changes in blood glucose levels and lipid profile. Garlic extracts have shown the significant (p<0.001)...
Anurag Sharma*, Naresh Kumar, Geetanjali Singh and Anika Sharma
...lycemic, hypo-lipidemic, antidiabetic, hepato-protective, anti-carcinogenic, anti-inflammatory, antibacterial, antifungal and galactagogue activity. The commercially available drugs pose health threats and prove detrimental to both human and animal health. The traditional use of herbal preparations suggests that they are safe and effective, however, scientific validation is still required for many of them especially for animal use. The phyto-pharmacological re...
Agustine Christela Melviana1, Rizkita Rachmi Esyanti1*, Roy Hendroko Setyobudi2, Maizirwan Mel3, Praptiningsih Gamawati Adinurani4 and Juris Burlakovs5
Gene Expression Related to Steviol Glycoside Synthesis Produced in Stevia rebaudiana (Bert.) Shoot Culture Induced with High Far-Red LED Light in TIS RITA® Bioreactor System
...dustry due to it’s antidiabetic properties, hence a large number of plant source is required to supply the industry. To overcome the hindrances in the propagation of Stevia plants using in vivo methods, an alternative technique of propagation using in vitro methods is needed. The micropropagation method with the RITA® (Recipient for Automated Temporary Immersion System) is used in the production of a large amount of stevia biomass in approximately a ...
Fahrauk Faramayuda1,2*, Totik Sri Mariani3, Elfahmi1,4 and Sukrasno1
...sia as an antibacterial, antidiabetic, antihypertensive anti-inflammatory. The country of Indonesia has three varieties of O. aristatus, namely purple, white-purple and white. The purple and white-purple population has started to decline. Efforts are needed to maintain the two varieties’ population, one of which is plant tissue culture. It is hoped that in vitro cultured plants contain the same secondary metabolites as the wild type. This study aims to i...
Syed Shahid Imran Bukhari1*, Nusrat Jahan2, Muhammad Khalil Ahmed Khan3, Mariam Zaheer1, Sabir Javed1
...adensis is known for its antidiabetic and antihyperlipidemic activity, this study was aimed to check efficacy and toxic limits of different doses of gel extract in diabetic induced albino mice. Male albino mice, weighing (25±5g) were divided into three groups; Group 1: normal (non diabetic nontreated), Group 2: diabetic non treated (DNT), Group 3: diabetic treated (DT) mice. Group 3 was treated with three doses of A. barbadensis (200 mg/kg, 300 mg/kg an...
Saydat Saad Abd El-Megeed1, Walaa Yehia El-Sayed1*, Tarek Khamis2
...are quite expensive. The antidiabetic activities of zinc oxide nanoparticles (ZnO NPs) were assessed in rats. ZnO NPs were characterized by transmission electron microscopy (TEM). Diabetes was induced by streptozotocin (STZ) -nicotinamide in rats, and some biochemical and molecular parameters were determined. The results revealed that ZnO NPs in combination with Empagliflozin suggestively declined the blood glucose levels, lipid profile, and liver and kidney f...
Owolabi Olutunmise Victoria1*, Saka Olusola Stephen2, Olashinde Oluwaseun Ruth1, Alli Smith Yemisi Rufina3
...nimals each to study the antidiabetic and antioxidative properties of young Cola acuminata leaves aqueous extract. Diabetes was induced using alloxan monohydrate.5 ml of normal saline was given to group I , group 2 received 5 mg/kg/ body weight of the standard drug glibenclamide, group 3 was given 140 mg/kg of alloxan while groups Young C. acuminata leaves aqueous extract was administered orally in graded doses to the diabetic animals (50mg/kg, 100mg/kg, 200mg...
Waheed Khan1, Muhammad Ajmal Khan2, Bakhtawar Khan1*, Aftab Amin3, Muhsin Ali4, Awais Farid, Ali Hazrat5 and Muhammad Yahya5
...ment could be a possible antidiabetic strategy. The objective of the most recent study was to assess Verbascum thapsus’s ability to combat hyperlipidemia and diabetes. Mice were given an intraperitoneal injection of alloxan (150 mg kg-1, b.w.) to cause diabetes. There were five groups of mice (n=10): group 1 (normal control) received normal food and water, group 2 (diabetic control) received normal food and clean water, group 3 (diabetic mice) received 2...
Jawad Ali1,*, Samiya Rehman1, Aqsa Aslam1, Fouzia Tanvir2, Rida Liaqat1, Muhammad Ahmad1, Aamir Riaz1, Muhammad Shafique3, Hassan Ali1 and Amjad Ali1
...dary metabolites imparts antidiabetic, hepatoprotective, hypolipidemic, antidepressant, immunosuppressive, anti-microbial properties to the W. coagulans Dunal. Plant samples from Mianwalli, Kohat, and Sargodha city were gathered for antioxidant potential determination. Free radical scavenging activity and total antioxidant activity experiments were performed on the samples using the DPPH and Phosphomolybdenum methods. Results shows leaves extract from Mianwali...
Abroo Fatima Qazi* and Din Muhammad Shaikh
...aimed to investigate the antidiabetic effects of polyunsaturated Omega-3-fatty in streptozocin (65 mg/kg body weight) induced diabetic Wistar rats. Animal were assorted to five groups: negative control group A and positive control group B and experimental groups C, D and E. Experimental groups C, D and E received Omega-3-fatty acid supplemented food in 0.3g, 0.4g and 0.5g/kg bodyweight dosage for 12 weeks, respectively. These Omega-3-fatty acids treated rats s...
ASIFA BASHIR1, AAMIR MUSHTAQ2* & TOOBA MEHBOOB3
...a potent antioxidant and antidiabetic agent....
MUHAMMAD NADEEM1, MUHAMMAD WASEEM MUMTAZ1&MUHAMMAD DANISH1
...mn;1.56 mg AAE/g DE) and antidiabetic effectbased on α-amylase inhibitory assay (IC50=42.91±1.24 μg/mL) was also depicted to be highest in the same extract. Based on current findings, 60% ethanolic extract of V. negundo leaves was revealed to be most potent for its antioxidant and α-amylase inhibition activity, hence could be used for formulation of new plant based functional food sornutraceuticals to improve human health....
HAFIZ MUHAMMAD ARSALAN1,2*, SUMMARA TABASSUM1, MUHAMMAD SHERAZ YASIN3, FAROOQ SALEEM4, ZEEMAL SEEMAB AMIN1, MUNIB ASHFAQ1, UMAR FAROOQ GOHAR5 & RASHIDA BASHIR6
...etle leaf can be used as antidiabetic drug because it is involved in lowering the blood glucose level and Piper betle leaf is a good source of anti-oxidants....
*Malik F. H. Ferdosi1, Iqra Haider Khan2, Arshad Javaid2 and Muhammad F. A. Fardosi3
...lamatory, antimicrobial, antidiabetic, antioxidant and/or anticancer activities....
*Arshad Javaid1, Iqra Haider Khan1 and Malik F. H. Ferdosi2
...ncer, anti-inflammatory, antidiabetic, and analgesic.
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Malik F. H. Ferdosi1, Iqra Haider Khan2, Arshad Javaid2*, Hafiz Muhammad Saeed1, Ifrayeem Butt2 and Ayesha Munir3
...atory, anticancer and/or antidiabetic properties....
Arshad Javaid1*, Malik F. H. Ferdosi2, Iqra Haider Khan1, Amna Shoaib1, Hafiz Muhammad Saeed2, Muhammad Abrar Ul Hassan1
...timalarial, antioxidant, antidiabetic, antitumor, etc....
Iram Alam Sthanadar1*, Muhammad Zahid1, Sami Siraj2 and Omar Malik2
Sana Eijaz, Asmat Salim* and Mohammad Anwar Waqar
...r data suggests that the antidiabetic activity of these herbs may be due to the action on insulin signaling genes and adipokines level along with the normalization of blood glucose and body weight. These herbs may offer a safe and economic strategy and has nutritional significance for the cure and prevention of type 2 diabetes....
Aamir Khan Awan1, Nighat Sultana1*, Rahmat Ali Khan2, Rifhat Sultana3,
Umm-e-Kalsoom1, Fayaz Ahmed Sahibzada4, Rifat Ullah Khan5, Naimat Ullah Khan6, Nazir Ahmad Khan7, Syed Haider Zaman8, Mir Sadiq Shah9 and Assar Ali Shah10*
...antioxidant activity and antidiabetic potentials of P. granatum peels extracts in alloxan-induced diabetic albino rats. The diabetes was induced in albino rats using alloxan at the concentration of 150 mg kg-1 body weight. After 15 days, the treated groups with glabinclemide and different varieties of methanolic and aqueous extracts showed a significant (P<0.05) decrease in the blood glucose level as compared to diabetic control while slight differences wer...
Bassant Mahmoud Emam1, Jehan Abd Elrazek Hassanen1, Abeer Gaffer Ali Hassan3, Azza Mahmoud Abdullah1, Hadeer Said Aboelnaga2, Amina Ali Dessouki2*
...already well-established antidiabetic drugs in the pharmaceutical sector like Dapagliflozin (DAPA). However, medicinal plant remedies, e.g., Fenugreek (Trigonella foenum-graecum), are efficiently utilized for DM treatment with low side effects. Accordingly, the study aimed to compare the effects of DAPA and Fenugreek seeds powder (FSP) or extract (FSE) on hyperglycemia, dyslipidemia, and hepatic alterations of streptozotocin (STZ)-provoked DM rats. Here, DM wa...
