BIOCHEMICAL ANALYSIS OF FLOWERS OF Vinca major, A MEDICINAL WEED PLANT OF HILLY AREAS OF PAKISTAN
BIOCHEMICAL ANALYSIS OF FLOWERS OF Vinca major, A MEDICINAL WEED PLANT OF HILLY AREAS OF PAKISTAN
Arshad Javaid1*, Malik F. H. Ferdosi2, Iqra Haider Khan1, Amna Shoaib1, Hafiz Muhammad Saeed2, Muhammad Abrar Ul Hassan1
ABSTRACT
Vinca major L. is an evergreen perennial weed of family Apocynaceae, growing naturally in hilly areas of Hazara region of Khyber Pakhtunkhwa, Pakistan. Flowers of this weed were collected during June 2021, shade dried and extracted in pure methanol for two weeks. After filtration, the extract was analyzed by GC-MS for the identification of possible bioactive compounds. α-Amyrin was the major compound (32.49%) followed by lup-20(29)-en-3-ol, acetate, (3β)- (25.72%). Moderately abundant compounds included γ-sitosterol (8.78%), β-amyrone (7.25%), cyclohexane, 1,3,5-triphenyl- (7.01%), olean-12-en-3-ol, acetate, (3β)- (5.68%), and n-hexadecanoic acid (3.18%). Some of the identified compounds have various important biological properties including anti-inflammatory, antimicrobial, anticancer, antimalarial, antioxidant, antidiabetic, antitumor, etc.
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