Aneeza Jamshed1* and Syed Amir Gillani2
...n (syringes 88.7%, blood transfusion 91%), signs (effects on liver 92.9%), symptoms (88%), prevention in high prevalent areas (sterilized syringes and screened blood transfusion 86.5%) and management (88.7%). This study showed that it may be an important school health based intervention to educate students about the transmission, prevention and management of hepatitis C, which may help in declining the disease burden. Hepati...
Ahmad Farooq1, Usman Waheed2,3, Hasan Abbas Zaheer2,3, Abdul Rauf4, Abida Arshad5, and Muhammad Arshad1,*
...dent upon lifelong blood transfusion. Multiple transfusions expose them to many blood borne diseases, most commonly hepatitis B and C. The aim of current study was to determine the prevalence of HBV and HCV infections among thalassaemia major patients. The study was conducted from June – December 2016, at the Thalassaemia Centre, Shaheed Zulfiqar Ali Bhutto Medical University, Islamabad and the Pakistan Thalassaemia Ce...
Ocheme Julius Okojokwu1*, Maryam Bisola Adebayo2, Bashiru Shafa Abubakar3, Ibrahim Abubakar Yusuf2 and Joseph Aje Anejo-Okopi1
...ildren, history of blood transfusion and trimester of pregnancy were statistically associated with prevalence of IgG antibody (p ≤ 0.05). There was a significant association (χ2 = 12.571; p = 0.028) between age group and IgG antibody. The age group > 40 years old had the highest prevalence of IgG antibodies while the age group 21 – 25 years (p ≤ 0.05) had the least (39.3%). Similarly, there was significant association (χ2 = 39.602; p <...
Saba Irshad*, Aruba Muhammad, Ammara Muazzam, Farah Sarfraz Anmol and Rehman Shahzad
...ely which minimize their transfusion frequency to 30 days in comparison to 7-15 days in Xmn1 -/- patients. Hematological analysis of thalassemic patients revealed low Hb, WBCs and platelets counts in contrast to control. The reported polymorphism was meant to be lowering the frequency of blood transfusions and to some extent responsible for diminishing the disease burden among ‘Thalassemia Major’ patients. <...
Farheen Shafique1, Shaukat Ali2,*, Saiqa Andleeb1, Abdul Rauf1,3, Syed Ayaz Kazmi1,3, Sadia Idrees4, Faisal Farooq1,3, Faiq Nawaz Khan3,4, Muhammad Saad-ul-Hassan1,3, Raja Awais Mumtaz1,3, Saba Khalid1, Zaheem Ashraf1, Hafiz Muhammad Tahir2 and Fazal-ur-Rehman5
...ral infections but blood transfusion in Beta thalassemic patients is working with two faces, one as remedy and the other is key risk factor in the spread of silent killers. Thalassemia patients registered in Combine Military Hospital (CMH) Rawalakot and Sheikh Khalifa Bin Zayed Al-Nahyan Hospital, Muzaffarabad Azad Jammu and Kashmir Pakistan were studied for the viral hepatitis B and C prevalence. A total of 303 (including 164 males and 139 females) individual...
Cornelius Arome Omatola*, Samson Daniel Iyeh, Shedrach James Abuh, Charles Kehinde Mofolorunsho, Martin-Luther Oseni Okolo and Phoebe Queen Akoh
...omen and husbands, blood transfusions, genital ulcers and trimesters were significantly related to a higher predisposition to STIs. Conclusively, a high prevalence of STIs was observed among asymptomatic pregnant women in the study area. Our findings highlight a concern with economic consequences. Hence intervention programs including comprehensive screening of pregnant women with increased access to health care and treatment of confirmed cases at an affordabl...
Joseph Anejo-Okopi1*, Ocheme Julius Okojokwu1 and Onyemocho Audu2
...exual intercourse, blood transfusion and vertical transmission. Therefore, there is a need for government commitment for HCV elimination program through making the DAAs available and its affordability to general population to curb the catastrophic cost of managing the epidemic. However, the diagnosis of HCV infection is faced with several challenges, therefore there is a demand for development of easy to use and inexpensive molecular methods for accurate diagn...
Joseph Anejo-Okopi1*, Dorcas Yilger Gotom1, Noble Allison Chiehiura1, Julius Ocheme Okojokwu1, David Ochola Amanyi2, John Otumala Egbere1, Joshua Adetunji1, Otobo Innocent Ujah3 and Onyemocho Audu4
The Seroprevalence of Zika Virus Infection among HIV Positive and HIV Negative Pregnant Women in Jos, Nigeria
... in the history of blood transfusion among the HIV positive participants, p=0.013. No association with educational level, employment, marital and resident, gestational trimester, fever, yellow fever vaccination, rashes and parity was found for anti-ZIKV IgG positivity in the groups. Our results showed high seroprevalence among the pregnant women, an indication that the ZIKV antigen that triggered the antibodies response is in circulation, therefore, suggest th...
Nosheen Basharat1, Usman Waheed2,3*, Muhammad Arshad1, Noor e Saba4, Iram Masood1, Akhlaaq Wazeer1, Ahmad Farooq1, Sadaf Moneeba1, Abdul Rauf5 and Hasan Abbas Zaheer2,3
... TTV is found with other transfusion transmitted infections, hence, preventive measures should be taken for better health of general population as blood donors represent healthy pool of society. TTV prevalence knowledge in Pakistan will help to develop strategy to control virus transmission in healthy population.
...
Samina Tahir Kiani1, Abdul Rauf1, Syed Ayaz Kazmi1,*, Nuzhat Shafi1, Madiha Khalid2, Naeem Latif1, Samina Gul2, Saghir Yousaf3 and Muhammad Arshad4
...gave positive PCR. Blood transfusion (p=0.0001) was found significant risk factor regarding spread of hepatitis B and C in the studied population.
...
Shoaib ur Rehman1, Jabbar Khan2*, Raaza Malja Khan3, Maimoona Azam4 and Zeeshan Mutahir5
...lies having at least one transfusion dependent child and sporadic patients from different areas of karak region. Using the amplification refractory mutation system-polymerase chain reaction (ARMS-PCR) technique, all samples were analyzed for the most common β-thalassemia mutations reported in Pakistani population. The most common mutations detected in karak region were frameshift codons (FSC) 8/9 (þG) (HBB: c.27_28insG), followed by IVS-I-5(G>C),...
Muhammad1, Saadat Mehmood1,2, Atif Muhammad1*, Zaib Ullah3
...he local population, the transfusion of blood from an infected person and unhygienic practices during surgery and medical treatment are the main causes of hepatitis. It is suggested to implement high care on the occasion of surgery, injection, and blood transfusion. Furthermore, awareness campaigns regarding blood transmission and health hazards of Hepatitis should be launched for the population.
Jun Zhang1*, Xiaocao Xu2 and Min Cao2
...er, age, number of blood transfusions per year, HBs-Ag, HCV-Ab and Anti-HBs. The study included 630 thalassemia major patients who received regular blood transfusions at a hospital in Bengbu, China. We found that out of 630 patients of the study, there were three HBs-Ag positive, so the prevalence of HBV in this study is 0.5%. The prevalence of HCV-Ab positive was 7.1 and these individuals had a significantly older mean age ...
Anum Syyam1,2, Nazish Saqlain1, Sidra Hareem1, Naghmana Mazhar1, Liaqat Ali3 and Samia Afzal2*
... is recommended that the transfusion of group O blood to non-O recipients should be done after evaluating the titer of anti-A and anti-B hemolysins....
Nina Chen1, Shuang Xu2, Juanjuan Lin1* and Moslem Lari Najafi3
Rimsha Ijaz, Rida Zahra, Naseer Ali Shah*, Haroon Ahmed, Nazish Bostan and Sadia Sattar
...te, are unscreened blood transfusions, unsterilized surgical instruments, and unsafe injections. Globally a total of about 170 million people have been afflicted with this malady per year and affects approximately (6%) of Pakistan’s population. HCV is RNA virus and there are seven primary genotypes and 67 subtypes in it. Determination of genotype is important for treatment and medication response. This study aimed to calculate the frequency of HCV infect...
MUHAMMAD AMJAD ALI1*, MUMTAZ AHMAD KHAN2, WAQAS AHMAD3, FAIZ-UL HASSAN4, SYED MUHAMMAD RAIHAN DILSHAD5, MIAN MUHAMMAD AWAIS1, MUHAMMAD IRFAN ANWAR1, MUHAMMAD RAZA HAMEED1 , MUHAMMAD ASHRAF SULTAN6 & HASEEB ANWAR7
...n was observed following transfusion of blood or Haes-sterilTM in any experimental dog. Hematological parameters like total leukocytic count (TLC), red blood cells (RBC), hemoglobin (Hb) and total proteins were also studied. Blood parameters such as RBC, Hb and total proteins were significantly different among dogs of both treatment groups. The changes in TLC values were insignificant amongst both treatment groups. Hypertonic colloid fluid can effectively be u...
