Safia Rehman1, Nazish Mazhar Ali1,*, Gerald B. Pier2, Iram Liaqat1 and Bushra Mazhar1
...cin, cefepime, cefixime, levofloxacin, and ciprofloxacin), Lactobacillus strains and metal nanoparticles (copper, ferric and zinc). P. aeruginosa isolates showed in vitro resistance against 11 of 14 antibodies tested. The isolates were highly susceptible to meropenem, piperacillin, and amoxicillin. It was also observed that the growth of these resistant P. aeruginosa strains was significantly inhibited in the presence of Lactobac...
Chaman Ara1*, Asmatullah1, Sehrish Kanwa1, Asma Chaudhary2, Ayesha Siddiqua1
... conducted to assess the levofloxacin induced hepatotoxicity, nephrotoxicity and its likely noxious effects on spermatogenesis in mammals. Forty mice, randomly categorized into four groups (N=10) were administered orally with different concentrations of levofloxacin (0.00, 9.37, 18.75 and 37.50µg/g BW of mice) for 30 days consecutively. Mice were sacrificed on 31st day (24 hours after last dose administered)...
Sana Khan1, Raheela Taj1, Noor Rehman2, Asad Ullah3, Imad Khan3 and Sadeeq ur Rahman3,*
...oprim-sulphamethoxazole, levofloxacin, ciprofloxacin and piperacillin-tazobactam, respectively, while, tygacil and colistin showed 100% susceptibility. On the other hands, 60%, 80%, 40% and 20% of metallo-β lactamase producers were found resistant to trimethoprim-sulphamethoxazole, levofloxacin, ciprofloxacin and piperacillin-tazobactam, respectively. Overall, current results show a high number of isolates resistant to ...
Mumtazur Rahman1, Farhan Anwar Khan1,*,Umar Sadique1, Ijaz Ahmad1, Shakoor Ahmad1, Faisal Ahmad1,2, Hayatullah Khan1,3, Muhammad Saeed1, Faiz Ur Rehman1, Ibrar Hussain1, M. Faraz Khan1, M. Izhar ul Haque1 and Hanif-ur-Rehman1,3
... including moxifloxacin, levofloxacin, ciprofloxacin, and enrofloxacin were selected for in vitro susceptibility of Mccp Pakistan strain. The concentration for each drug was measured distantly depending on high concentration available in the market and was then used in various concentrations ranges from higher to lower i.e. moxifloxacin 80-0.156 µg/ml, levofloxacin 250-0.488 µg/ml, ciprofloxacin and enrofl...
Mohamed S. Hussein1*, Hanan A. Fahmy2, Ashraf A. Abd El Tawab3
... and lowest rate against levofloxacin (33.3%). A total of 24 isolates, dsplaying high resistance to at least 5 fluroquinolone antibiotics, were then screened for plasmid-mediated quinolone resistance (PMQR) genes qnrA, qnrB, qnrS, qepA and aac(6′)-Ib-cr by PCR. The results revealed that 22 isolates (91.7%) harboured at least one PMQR gene, with qnrS being the most frequent (83.3%). The qepA, qnrB and aa (6′)-Ib-cr genes occurrence was 54.2%, 16.7% ...
Nina Chen1, Shuang Xu2, Juanjuan Lin1* and Moslem Lari Najafi3
...ancomycin hydrochloride, levofloxacin hydrate, metronidazole and fluconazole increased gradually. The particle size of fosfomycin sodium in the mixture containing gentamicin sulfate, abacain sulfate, minocycline hydrochloride, ciprofloxacin and/ or ciprofloxacin also changed significantly after preparation. We concluded the particle size changes of some drugs indicate that these drugs may cause changes in fat particle size during administration. Therefore, the...
Md. Saiful Islam Siddiqui1*, Sharmin Akter2 and Mohd. Riajul Islam2
Maria Azam1, Tahir Mahmood Qureshi1, Saddam Hussain2, Amjad Islam Aqib3*, Shanza Rauf Khan4, Kashif Akram1, Misbah Ijaz5, Maheen Murtaza6, Afshan Muneer6 and Sammina Mahmood7
...entamicin, enrofloxacin, levofloxacin, and vancomycin was found to be 50, 40, 30, 30%, respectively. On the other hand, a disc diffusion assay was concluded with 24.525±0.806 mm (ZnO) followed by 16.475±0.950mm (MgO) and 13.150±1.392mm (Fe2O3). MgO stood first to contribute lowest Minimum inhibitory concentration (MIC) (1.302±0.564 mg/mL) followed by Fe2O3 (2.930±1.691 mg/mL) and ZnO (3.906±0.000 mg/mL). MIC of ZnO was...
MUHAMMAD ASLAM*, ASAD GULZAR, AMINA ASGHAR, MISBAH IRSHAD, ZAHRA NOREEN, SADAF JAVAID, ABRAR HUSSAIN, UMAIR AHMAD & SAMREEN KOUSAR
...t, for the validation of levofloxacin in injection form. The λmax for
levofloxacin was found to be 293nm using 0.1N HCl as a blank.
Calibration curve data proved that the proposed method was linear in
the concentration range of 3 to 7μg/mL. The proposed method was
validated to determine linearity, precision, accuracy, ruggedness and
...
Mohammed Mijbas Mohammed Alomari1, Nawar Jasim Alsalih2*, Samir Sabaa Raheem2, Mohenned Alsaadawi2, Ali Mosa Rashid Al-Yasari3
Enany M.E.1, Fadel Hanaa M.2, Abo-Shama U.H.3, Ahmed Mona M.1, Kholief M.E.A.4*
...ally for felines against levofloxacin, tetracycline and amoxicillin in presence of vacA 100%, otherwise deficient vacA isolates of sheep; nitrate and non-nitrate biotypes from milk and congested gut in summer and spring, respectively representing cagA & hrgA 50% have sensitivity 0% till 28.6%. In conclusion, the highest resistance to cagA of H. pylori in autumn season and the highest sensitivity for hrgA in winter season was recorded.
Faiza Ghazanfar1, Masood Rabbani1*, Aamir Ghafoor2 and Muhammad Hassan Mushtaq3
...(27%), gentamicin (25%), levofloxacin (24%), ofloxacin (20%), imipenum (4%), meropenum (2%) and ceftazidime (1%). Carbapenums (imipenum and meropenum) and cephalosporin (ceftazidime) was found to be highly effective against these MDR thermophilic C. jejuni isolates. Its efficacy for the treatment of campylobacteriosis should be further evaluated in clinical trials....
