Zhiyuan Sun1, 3, Xuhui Zhang2,*, Xian Li3, Yanping Huang3, Shiyan Sui3, Weifeng Liu3, Guochao Ni3, Xiaozhou Xu1, Jianbo Yang1, Xue Lian1 and Hui Jia1
...;">The crosstalk between glucocorticoid (GC) and immune response is critical for the maintenance of homeostasis. However, it remains elusive whether chronic stress affects lipopolysaccharide (LPS) -induced inflammation via the crosstalk. Pigs were administered LPS injection with or without continuous adrenocorticotropine hormone (ACTH) pretreatment. Twenty-four 30-day-old Duroc × Landrace × Large White crossbred piglets (12 ± 0.5 kg) were ra...
Rafiqul Islam1, Nasrin Sultana1*, Md. Abu Hadi Noor Ali Khan2
...y administered synthetic glucocorticoid. The focus of this study was determining how DEX affects serum biochemistry (cholesterol and triglycerides), morphology, and morphometry of broiler hearts. Eighty one-day-old chicks (DOCs) were randomly categorized into four groups i.e., one control group and three trial groups (i.e., E1, E2, and E3). The control group was given commercial broiler feed and the trial groups were given commercial broiler feed containing DE...
Mingqing Wang1 and Xiaojuan Chen2,*
...he therapeutic effect of glucocorticoid combined with respiratory stimulant on patients with AECOPD along with the optimal nursing care required for these patients. Also, tumor necrosis factor-alpha (TNF-a) was assessed as an inflammatory factor to see the response to treatment. In this study, 180 AECOPD patients who had been treated in our hospital were enrolled as research objects, who were given routine respiratory stimulant therapy regimen and intravenous ...
Xiaowei Huang1, Chao Ma1, He Lin1, Yuchen Wang1, Yan Xu1, Guangfu Lv2* and Zhe Lin1*
...s. The protein levels of glucocorticoid receptor (GR), mineralocorticoid receptor (MR), brain-derived neurotrophic factor (BDNF), trosine kinase B (TrkB) and cyclic adenosine monophosphatec response element binding protein (CREB) in hippocampus were detected by western blotting. The results showed that, OR could significantly reduce the contents of CRH, ACTH and CORT in serum and improve the damage of hippocampal structure, and increase the expression levels o...
Feng-Yan Liu1,2,3, Ting Chen1,2,3, Yu-Hui Li1,2,3, Zheng Liu1,2,3, Jing-Jin Zheng1,2,3, You-Bang Li1,2,3* and Zhong-hao Huang1,2,3*
...gical hormones including glucocorticoids (GCs), cortisol, and thyroid hormones (THs, T3 and T4) of rhesus macaques’ (Macaca mulatta) fecal pellet sampled from the Longhushan Nature Reserve, Southwest Guangxi, China. The results indicated that cortisol was negatively correlated with ambient temperature and sunlight, whereas T4 was positively correlated with sunlight. Cortisol levels sampled from spring/winter were higher than those sampled from summer/fal...
Physiological Effect of Glycyrrhizic Acid on Adrenal Insufficiency Induces by Glucocorticoid in Rats
Wafaa AL. Bnyean1,2 ,Zainab A.H. AL-Mousawi1*
... insufficiency caused by glucocorticoids in female rats. Fifty female rats were divided randomly into five groups. Negative control group(G1): Normal saline was given orally to rats. Positive control group(G2): rats for seven days were treated with Hydrocortisone Sodium I.P. (50 mg/kg). Therapeutic group(G3): rats for seven days were treated with Hydrocortisone Sodium I.P. (50 mg/kg) and then 14 days with GA (100 mg /kg) orally. Protective group(G4): Rats were...
