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M. S. Joshi , D.M. Sawant and A.P. Gaikwad

Isolate variations in Colletotrichum gloeosporioides infecting pomegranate

...ties. Fruit varieties Aarakta and Bhagwa were found to be highly susceptible as both displayed maximum mean DRI 10.38 and 8.56, respectively irrespec-tive of isolates. Resistant varieties Yarcud local and Bedana thin skin showed uniform resistant reaction against six isolates of the pathogen. The interaction between isolates x varieties was also statistically significant. Highest DRI (15.22) was recorded in the interaction between Bhagwa x Cg 85 and it was on ...

Effect of Butyrate on Genetic Expression of Sirt1/AMPK and Akt/mTOR Axes in Murine Adipose Tissue

Tania A. Shakoori^1,*, Soumble Zulfiqar², Khadija Irfan Khawaja³ and Faisal Masud⁴

Farmers Empowerment by Farm Services Centers: A Pedagogic Approach for Sustainable Development

Muhammad Zafarullah Khan^1*, Rehmat Ullah¹, Asif Nawaz¹ and Ejaz Ashraf²

...role in technological breakthroughs. It is therefore, suggested that these agricultural companies must be allowed for demonstration to train farmers on their innovations under Farm Services Center’s

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A Review about Perspectives of Nanotechnology in Agriculture

Safdar Ali^1*, Obaidullah Shafique¹, Tariq Mahmood², Muhammad Amir Hanif¹, Ijaz Ahmed³ and Bashir Ahmad Khan⁴

...e soil. Another major breakthrough of nanotechnology for improvement in agriculture production is the development of insect-resistant varieties by DNA transfer in the plants or nanoparticle-mediated gene. Biofuel production from biomass is estimated to speed up using nanotechnology. Researchers and manufacturers have to demonstrate that the application of nanotechnologies have no harmful effect on the atmosphere against the anomaly based only on small amounts ...

Computational Pharmacophore Modelling of 5-HT2a and D2 Receptor Inhibitors of Schizophrenia

Rida Zainab¹, Sana Elahi¹, Afshan Kaleem^2,*, Daniel C. Hoessli³, Mehwish Iqtedar², Roheena Abdullah², Faiza Saleem², Shanza Khan¹, Anusha Ijaz¹, Shagufta Naz²and Abdul R. Shakoori^4,5,*

Assessing Suitability of Wheat Genotypes for Growth, Yield and Nutrients Uptake under Sand Culture

Asad Ullah Khan¹, Wiqar Ahmad^1*, Amir Raza², Farmanullah Khan³ and Muhammad Sharif³

...9), Tatara-96 (WS 395), Paktunkhwa-15 (PR-103), NIFA Lalma (NRL 0517), Pirsabak 2013, NIFA Insaf (NRL 0707), Shahkar-2015 and Pirsabak 2015 (PR-105). Pots were arranged in completely randomized design in a glass-house at the Nuclear Institute for Food and Agriculture (NIFA), Peshawar, during 2016. Hoagland solution was used as irrigation and plant nutrition applied at 3 days interval. Environmental variation was minimized through constant shuffling of pots eve...

Piceatannol Inhibits Akt Activation, Induces G2/M Phase Arrest and Mitochondrial Apoptosis and Augments Cisplatin Efficacy in U2OS Osteosarcoma Cells

Zijuan Li^1,2, Rong Ma², Muhammad Khan³*, Chenchen Liu², Xiaolin Cui² and Yongming Li^1,2*

Piceatannol Inhibits Akt Activation, Induces G2/M Phase Arrest and Mitochondrial Apoptosis and Augments Cisplatin Efficacy in U2OS Osteosarcoma Cells

Spotting rs112445441 in Non-Hodgkin Lymphoma: Another Clue for the Context-Dependent Crosstalk between RAS-MAPK and PI3K Mediated Pathways

Bibi Nazia Murtaza¹, Mazhar Saeed Chaudry², Shamaila Inayat Nadeem¹, Muhammad Shahid Nadeem³ and Abdul Rauf Shakoori^4,*

miR-22-3p Suppresses Adipocyte Formation of Telomerase Transformed Mesenchymal Stromal Cells (iMSC3) by Regulating Non-targeted MAPK Signaling Pathway

Sara Sultan Alomran¹, Muhammad Nasir Khan Khattak^1,2, Amir Ali Khan^1,2*, Sallam Hasan Abdallah², Abeer Maher Fayyad¹ and Khalid Bajou^1,2

Oriental Leafhopper (Hemiptera: Cicadellidae: Parallygus) First Report from North West Pakistan with Redescription of Parallygus rameshi Viraktamath and Webb

Hassan Naveed¹*, Kamran Sohail², Gul Zamin Khan³ and Yalin Zhang²

...of Parallygus rameshi Viraktamath and Webb, 2012. A worldwide checklist with distribution for species of genus Parallygus Melichar is also provided.

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Preference of Cotton Jassid, Amrasca Devastans, Towards Different Okra Cultivars Having Variable Physio-morphic Characteristics

Naima Din¹, Misbah Ashraf¹, Muhammad Rizwan²*, Muhammad Babar Shahzad Afzal⁴, Hafiz Ghazanfar Abbas², Farrukh Ilahi², Amir Hameed5, Muhammad Ahsin Ayub⁶, Qurban Ali¹ and Muhammad Farooq^2,3

... Okra viz., Sabz Pari, Shakti Hybrid, NS-810, OK Advanta-803 and NS-801 were tested for resistance against Amrasca devastans (Dist.) at the farm area of Vegetable Research Institute, Ayub Agricultural Research Institute (AARI), Faisalabad in 2018-19. Observations regarding the population of A. devastans were recorded from 20 leaves per treatment at random (upper, lower, middle leaves), Physio-morphic characters viz., plant height, number of branches, area of l...

Effect of Hedyotis diffusa Polysaccharide on Apoptosis of Thyroid Cancer Cells

Lin Lu

Effect of SSAT on the Proliferation and Apoptosis of Prostate Cancer Cells via Regulation of Akt, GSK-3β and β-catenin Expression

Xian Zhang¹, Erjiang Lin¹, Shizhe Hong¹ and Zhengjie Zhu²*

Protective Effect of Buyang Huanwu Decoction on Diabetes-Induced Damage to Hippocampal Neurons by Regulating PI3K-AKT/Bcl-2 Pathway

Wei Cui¹, Yanwei Du¹, Lijuan Jiang¹, Yan Wei¹, Yuguo Li¹, Wenfeng Zhang¹* and Ling Zhang²*

Post-Ischemic Treatment with Sevoflurane: To Reduce Myocardial Ischemic/Reperfusion Injury in Rats by miR-26a-5p/PTEN/PI3K/Akt Signaling Pathway

Shaolin Zeng, Shuai Yuan* and Kai Liu

Effect of Caffeine Citrate with Aminophyline on Apoptosis and Respiratory Endothelial Cell Dysfunction in Premature Infants

Hongfeng Guo

Effect of miR-4728-3p on the Regulation of PTEN in Apatinib-resistance SCLC Cell Line

Fang Chen

Valuation of Massive Artificial Insemination Programs and the Economic Impact for Indonesia

Achmad Firman¹*, Sondi Kuswaryan¹, Lilis Nurlina¹, Muhamad Hasan Hadiana¹, Marina Sulistyati¹, Unang Yunasaf¹, Dwi Cipto Budinuryanto², Iman Trisman³

...griculture has made a breakthrough in increasing the cattle population to reduce supply inequality through a massive artificial insemination program (SIWAB/SIKOMANDAN). Previously, the artificial insemination program was carried out partially and not with the feed, health, and community services programs. However, feed, animal health, veterinary public health, and community services are a part of the SIWAB/SIKOMANDAN program. The purpose of the study was to as...

The Transcriptional Regulation Mechanism of Transgelin Gene in Colon Cancer Cells

Qi Zhuo, Yuanchun Yao, Meisongzhu Yang* and Jinhua Chen and Miao Tian

Effect of MTOR Inhibitor Combined with Photodynamic Therapy on the Regulation of Cancer Stem Cells through Reactive Oxygen Species

Yakun Ge

Effect and Mechanism of Marein on Diabetic Retinopathy

Zhipeng Song^1,2, Jialiang Xin^1,3, Xiaoli Wei^1,2, Abula Zulipiya^1,3, Kadier Kedireya^1,2 and Xinmin Mao^1,3*

The Expression and Distribution of MIF, ERK, Akt and Rb/E2F in Pulmonary Hypertension in Broilers

Yanmei Wang^1,2, Haoyun Li¹, Lijuan Han¹and Wenkui Wang¹*

Mechanism of Action of Velvet Antler Polypeptide in Improving Mild Cognitive Impairment in Rats

Xiao-Wei Huang^1,2, Mei-Li Liu¹, Jin-Ji Wang¹, Yue-Xin Liu³, Zhe Lin¹, Chun-Shu Rong⁴* and Ji-Xiang Ren⁴*

Mutation Profiling of PI3K/AKT1/MTOR Pathway Genes in Breast Cancer Patients of Pakistan

Muhammad Javed Iqbal¹, Farah Rauf Shakoori¹*, Bushra Muneer² and Abdul Rauf Shakoori³

Alzheimer’s Disease: Pathogenesis, Hypothesis and Management

Rabia Anjum

...ight on the potential breakthroughs, such as aducanumab, while acknowledging the ongoing quest for more targeted treatments that address the fundamental causes of this multifactorial neurodegenerative disease.

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Advancements in Vaccination Strategies: From Historical Milestones to Modern Innovations in Viral Disease Prevention and Public Health

Kashif Abdaal, Aneeza Batool, Muhammad Tariq Navid*, Saeed Ahmed, Asma Saleem Qazi, Waseem Safdar, Haidar Ali, Mobeen Ur Rashid, Somia Rafaqat

...the vaccines as a big breakthrough in preventive and therapeutic medicine over 200 years and named “Future Medicine”. To assess vaccine safety and efficacy, scientists are now using various model animals like mice, ferrets, pigs, and nonhuman primates before using them for human trials. The other side of successful vaccine intervention, however, contains various issues that need to be rectified. These concerns primarily depend on target pathogen se...

Vegetation cover change in Manglot Wildlife Park, Pakistan: an indicator of success or a dilemma in management

Ahmad Khan and Muhammad Ayaz Khan

...istan, Wildlife, Khyber Paktunkhwa, land use change.

...

Impact of Various Fiber Sources in Ration Formulas on Feedlot Performance of Sheep in Indonesia

Efi Rokana1, Iin Rohmatul Fatimah1, Brilian Desca Dianingtyas1, Niswatin Hasanah2, Wulandari3, Zein Ahmad Baihaqi1,3*

... years. One potential breakthrough is utilizing waste from various agricultural fiber sources in remote villages. This study aimed to investigate the impact of feeding different types of forage in the ration formula on sheep feedlot performance. Twenty-seven female local sheep (fat tailed) were utilized as research subjects. The study involved sheep rations comprising various ingredients, with three distinct research factors: elephant grass, corn plants, and r...

Isolation and Identification of Newcastle Disease Viruses from Naturally Infected Chickens

Yasser Asaad Hameed Al-Shareef, Firas Hussain Kadim Abawi*

...on status, indicating breakthrough infections. In order to investigate the nature and dynamics of these breakthrough infections, samples were collected from infected flocks with existing clinical signs of the disease. Attempts to isolate, identify and characterize positive samples were made by inoculating chicken embryonated eggs followed by haemagglutination and haemagglutination inhibition assays. Using reverse transcripta...

Dynamic Effects of Ketogenic Diet on Autophagy and Cell Cycle in a Mouse Model of CT26+ Colon Cancer

Junrong Yang¹, Ning Zhang¹*, Muhammad Akram Khan², Qingpeng Wang¹*, Zhengping Wang¹*, Quiqin Liu³, Lanjie Li³, Jun Han¹, Abdul Asim Farooq⁴, Aayesha Riaz⁵ and Ruiyan Zhang¹

Breakthroughs in SARS-CoV-2-monoclonal antibodies development

Yusuf Muhammed; Mkpouto Pius; Bashiru Sani; Bulus Timothy; Jafar Usman; Musa Garba

Novel Research in Microbiology Journal (2021), 5(1): 1063-1076

Effect of TRAF6 on Proliferation of Prostate Transitional Zone and Peripheral Zone Cells

Yulin Zeng

Study on the Treatment of Experimental Dermatitis with Ginkgo biloba Leaf Extract and Quercetin

Minghui Xiao, Minjie Huang, Jie Dong and Deqian Wang*

Adenosine Deaminase Acting on RNA1 (ADAR1) Deficiency Promotes Proliferation of Hemangioma-Derived Endothelial Cells via PI3K/Akt/mTOR Pathway

Chaoqi Yin¹*, Ruyi Tao¹, Kaixi Tan² and Jianfei Zhang³

Carvacrol Induces Doxorubicin-Resistant Breast Cancer Cell Apoptosis via Inhibition of the PI3K/Akt Pathway

Hu-Hu Chen^1,2*, Jiao-han Zhou³ and Siat Yee Fong^2,4

Key Genes Associated with Nonalcoholic Fatty Liver Disease and Colorectal Cancer in Experimental Animal Models

Fan Zhang¹, Shuai Han² and Weijie Song¹*

Unknown

Muhammad Zafarullah Khan^1*, Rehmat Ullah¹, Asif Nawaz¹ and Ejaz Ashraf²

Kashif Abdaal, Aneeza Batool, Muhammad Tariq Navid*, Saeed Ahmed, Asma Saleem Qazi, Waseem Safdar, Haidar Ali, Mobeen Ur Rashid, Somia Rafaqat

Efi Rokana1, Iin Rohmatul Fatimah1, Brilian Desca Dianingtyas1, Niswatin Hasanah2, Wulandari3, Zein Ahmad Baihaqi1,3*

Yasser Asaad Hameed Al-Shareef, Firas Hussain Kadim Abawi*

Pakistan Journal of Zoology

Featuring

Therapeutic Efficacy of Acupuncture Targeting GV-1 Acupoint on Diarrhea Induced by Sennae Folium in Rabbits

A New Species of Prochora Simon, 1886 (Araneae: Miturgidae) and Some New Records of Superfamily Lycosoidea (Araneae) from Margalla Hills National Park, Pakistan

Phillygenin Ameliorates Neuropathic Pain by Inhibiting TLR4/MyD88/NF-κB Pathway in Rats

Breeding and Nesting Behaviour of Red-Vented Bulbul (Pycnonotus cafer) in Shaheed Benazirabad District (Tropical Thorn Forest) Sindh Province of Pakistan

Unknown

Muhammad Zafarullah Khan1*, Rehmat Ullah1, Asif Nawaz1 and Ejaz Ashraf2

Kashif Abdaal, Aneeza Batool, Muhammad Tariq Navid*, Saeed Ahmed, Asma Saleem Qazi, Waseem Safdar, Haidar Ali, Mobeen Ur Rashid, Somia Rafaqat

Efi Rokana1, Iin Rohmatul Fatimah1, Brilian Desca Dianingtyas1, Niswatin Hasanah2, Wulandari3, Zein Ahmad Baihaqi1,3*

Yasser Asaad Hameed Al-Shareef, Firas Hussain Kadim Abawi*

Pakistan Journal of Zoology

August

Featuring

Therapeutic Efficacy of Acupuncture Targeting GV-1 Acupoint on Diarrhea Induced by Sennae Folium in Rabbits

A New Species of Prochora Simon, 1886 (Araneae: Miturgidae) and Some New Records of Superfamily Lycosoidea (Araneae) from Margalla Hills National Park, Pakistan

Phillygenin Ameliorates Neuropathic Pain by Inhibiting TLR4/MyD88/NF-κB Pathway in Rats

Breeding and Nesting Behaviour of Red-Vented Bulbul (Pycnonotus cafer) in Shaheed Benazirabad District (Tropical Thorn Forest) Sindh Province of Pakistan

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Muhammad Zafarullah Khan^1*, Rehmat Ullah¹, Asif Nawaz¹ and Ejaz Ashraf²