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Kaori Sasaoka1, Takahiro Kataoka1, Norie Kanzaki1, Yusuke Kobashi1, Akihiro Sakoda2, Yuu Ishimori2 and Kiyonori Yamaoka1,*
...ers; however, it induces nephrotoxicity caused by oxidative stress. Here, we investigated whether radon inhalation has different effects against CDDP-induced renal injury in two mouse strains differing in radiosensitivity, and determined the appropriate dose of CDDP combined with radon inhalation for highly radiosensitive mice. CDDP was administered at 20 mg/kg weight to C57BL/6J and BALB/c mice after radon inhalation at 1000 Bq/m3 and 2000 Bq/m
Chaman Ara1*, Asmatullah1, Sehrish Kanwa1, Asma Chaudhary2, Ayesha Siddiqua1
... induced hepatotoxicity, nephrotoxicity and its likely noxious effects on spermatogenesis in mammals. Forty mice, randomly categorized into four groups (N=10) were administered orally with different concentrations of levofloxacin (0.00, 9.37, 18.75 and 37.50µg/g BW of mice) for 30 days consecutively. Mice were sacrificed on 31st day (24 hours after last dose administered) under deep chloroform anaesthesia. Blood was extracted through cardiac p...
Sameh S. Tawfik, Ahmed A. Elkady* and Ehab T. Mohamed
...nst γ-rays-induced nephrotoxicity in irradiated rats was investigated. Forty albino-rats were divided into four groups: Control, rats were orally administered the vehicle for 6weeks, TSE-treated (each rat received 230mg TSE; once daily, for 6weeks), irradiated (animals subjected to whole body γ-rays (8Gy), and TSE-treated and irradiated (each rat received 230mg TSE; once daily for 6week, then one-hour later after last-treatment, rats were exposed t...
Ahmed H. Massoud1, Mohamed S. Ahmed2, Moustafa Saad-Allah1, Aly S. Derbalah1, Ashraf Albrakati3* and Ehab Kotb Elmahallawy4*
...ally, hepatotoxicity and nephrotoxicity were obvious in rats treated with cymoxanil, meanwhile, neuronal and pulmonary changes were nearly the same in all doses of the used pesticides. Taken together, our study recommends examining pesticides for their possible adverse effects on animals and humans in case of repeated use, even in small doses, before their application to agricultural fields.

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Shaimaa A.Tawfik2,3, EL S.T. Awad1*, Hoda O.Abu Bakr1, Amira M.Gamal-Eldeen4, Esmat Ashour2, Ismail M.Ahmed1  

...ssion in hepatotoxicity, nephrotoxicity and cardiotoxicity induced by DOX in male albino rats evidenced by a significant enhancement in the activity of ALT, GGT, LDH, AST, also creatinine and uric acid. CSO induced antioxidant activity GSH, CAT and inhibited MDA. Histopathological examination in sections of liver, kidney and heart tissues were confirmed these findings. In liver tissues, DOX resulted in an observable induction in CYP3A4 and MRP-1, while CSO/DOX...

Rahma Boukarine*, Leila Hamdi and Kamel Khelili

...duced hepatotoxicity and nephrotoxicity in wistar rats, while the combination of this solvent with rocket aqueous extract (Eruca sativa) attenuated this toxicity thanks to its antioxidant property.

...

Haneen Imad Al-Sultani1*, Ahmed Obaid Hussain1, Hazar Shakir Saleh2 

...tin in high doses causes nephrotoxicity.   

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Abeer Alahmari1,2*

...idative stress-dependent nephrotoxicity caused by ethanol in rats. Male Sprague‒Dawley rats orally received 40% ethanol (3 g kg-1) and were then orally treated with (500 mg kg-1) AME daily for 30 days. Kidney function, oxidant and antioxidant status, and histopathology alterations in renal tissue were measured. Animals that received ethanol displayed nephrotoxicity, as confirmed by markedly increased serum creatinine, ur...

Mariam Ismail Ali1*, Rania Helmi Abdou1, Mary Ayad Sargious2, Omnia Mohamed Khattab2, Kawthar Abdelwahed Elhady1

...chloride hepatotoxicity, nephrotoxicity, and neurotoxicity in rats. The study found that cadmium treatment in rats increased inflammatory markers (TNF-α 264.3% and IL-1β 170.7%), and oxidative markers(MDA 140.5%), Higher liver enzymes, histopathological lesions, and genes expression screened for hepatotoxic effects. Bee venom effectively reduced inflammation (TNF-α 49% and IL-1β 41.4%) and oxidation (MDA 36.8%), reduced liver enzymes, and...

Mayada Sahib Hassan1*, Hayder Talib Mahdi1, Sajaa R. Al-Saedi1, Ali Farid Shakir1, Ali J. Al-Nuaimi1, Marwa Sabah Majed1, Ridha Adel Fahad1, Karar Ali Kadhim1, Mustafa Ali Noor1, Ameer Hameed Kadhim1, Hussein Ali Mohammed Hadi1, Zainab Amori Oribi2, Mazin Talib Abbas3, Mahdi S. Hassan4 

...nst lead acetate-induced nephrotoxicity. In experimental animals, forty adult male albino rats were utilized. Four groups of animals were used in the study. Ten male rats each group are used: Group 1 (control group): For 28 days, the animals were given distilled water orally. Group 2 (lead acetate group): For seven days, animals in this group received intraperitoneal injections of lead acetate at a dose of 30 mg/kg B.W. every day, depended on LD50. Group 3 (Tr...

Journal of Animal Health and Production

November

Vol. 12, Sp. Iss. 1

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