Jose M. Rojas, Noemi Sevilla and Veronica Martin
...an overview of the known immunosuppressive strategies of PPRV, among the Paramyxoviruses, as well as the strategies developed by this virus to evade the immune system, focusing on the newly identified factors involved. In the last years substantial progress has been reported in the identification of viral factors involved in the host immunosuppression, although future studies employing in vivo infection models are needed to clearly understand the mechanisms de...
Gabriela Mansano do Nascimento, Helena Lage Ferreira and Clarice Weis Arns
...e, highly contagious and immunosuppressive disease in young chickens. The first line of defence against the virus is innate immunity whose activation is independent of the antigen and depends on the ability of the host to recognize pathogens by means of specific pattern recognition receptors. This interaction induces the production of cytokines, chemokines and interferons. Through Janus kinase/signal transducers and transcription activators pathway, interferon...
Tasleem Akhtar, Nadeem Sheikh*
Induction of acute phase in response to tacrolimus induced hepatotoxicity
...o the toxic effect of an immunosuppressive drug (tacrolimus). Aqueous suspension of tacrolimus powder (3 mg/ml) was orally given to four experimental groups of wistar rats. Control group was provided with normal drinking water and dissections were done after 6, 12, 24 and 48 h of tacrolimus dose. Densitometric analysis revealed considerable elevated level of some positive acute phase proteins, specifically C-reactive protein, haptoglobin and ceruloplasmin. Whi...
Altaf Hussain1*, Muhammad Saad Ashraf3, Asim Shamim1, Mohsin Nawaz1, Arslan Mehboob2 and Urooj Fatima2
...the most devastating and immunosuppressive diseases of the poultry and has been a constraint on the sustainable food security around the globe including Pakistan. Poultry industry is the second biggest industry in Pakistan while IBD is an important disease seriously threatening poultry farming. Despite the use of mass and intense vaccination regimens, the disease continues to sustain in many countries around the globe including Pakistan. However, to some exten...
Syeda Fakhra Waheed1, Asim Aslam1*, Muti-ur-Rehman Khan1, Kamran Ashraf2 and Beenish Zahid3
...ne of the most important immunosuppressive diseases of the poultry and has been a constraint on sustainable food security around the globe, including Pakistan. This disease damages the bursa of Fabricius (BF), which causes immunosuppression in birds. A total of 50 tissue samples from backyard chicken flocks presenting suspected symptoms were collected during February 2020 and March 2021 for genetic characterization, followed by phylogentic analysis. A total of...
Ahmad Shahzaib1*, Tabish Raza2 and Aisha Areej2
... Current clinical use of immunosuppressive therapies, including cytokine blockade, JAK, and IL-6 inhibition in severely ill COVID-19 patients, is associated with increased secondary infections. Therefore, the current review aims to collect literature on the incidence of COVID-19 co-infections and immune-inflammatory responses to such infections. A better understanding of immune-inflammatory markers of COVID-19-associated coinfections is vital to advance COVID-...
Jawad Ali1,*, Samiya Rehman1, Aqsa Aslam1, Fouzia Tanvir2, Rida Liaqat1, Muhammad Ahmad1, Aamir Riaz1, Muhammad Shafique3, Hassan Ali1 and Amjad Ali1
...pidemic, antidepressant, immunosuppressive, anti-microbial properties to the W. coagulans Dunal. Plant samples from Mianwalli, Kohat, and Sargodha city were gathered for antioxidant potential determination. Free radical scavenging activity and total antioxidant activity experiments were performed on the samples using the DPPH and Phosphomolybdenum methods. Results shows leaves extract from Mianwali has the highest total antioxidant capacity while stems collect...
Azza M. El-Kattawy1, Tarek Abou Zed1, Randa Megahed1 and Mohammed El-Magd2*
Ahmed Al-Hasnawi*, Wafaa Kadhim Jasim
...ver damage brought on by immunosuppressive drugs such azathioprine differs from the positive results attained by giving male rats (aloe vera extract) and lowering the toxicity.
Keywords | Azathioprine, Aloe vera, Hematological, Liver’s function enzymes, Histopathological, Male rats
... 
Madbouly*, H.M.; Saif**, M.A. and Hussein* , A.S.
... that MDV vaccine has an immunosuppressive effect on chicks and this could be antagonized by immunostimulant as curcuma longa The surprising immuno-stimulatory effect of curcuma is in the induction of protection level 80% in treated but not NDV vaccinated group which equivalent to that group vaccinated with NDV vaccine only and not treated. From the obtained results we recommend the use of curcuma longa powder in poultry rations for enhancing the immune respon...
M.A. Farag*, Abeer, E. Mansour* and s.M.
...d low values of AOD. The immunosuppressive effects of BVDV and AFBI on the immune response of sheep vaccinated with bivalent FMD vaccine were discussed....
Saadeya Ali Lefelef Al-Gnami1, Fatima Ibrahim Mohammad2, Huda Jassim Mohammed Al-Helali3
...ir anti-inflammatory and immunosuppressive properties. Vitamin C and Nanopiperine are crucial in mitigating the effects of free radicals by acting as antioxidants.The study investigates the positive impacts of piperine nanoparticles and vitamin C on several blood parameters and liver tissue in male rats treated with dexamethasone. The forty-eight male rats were randomly divided into six groups. Nanopiperine (15 mg/Kg.B.W) was given orally to the T1 group. Vita...
