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Molecular Biology, Immunosuppression and Pathogenesis of Infectious Bursal Disease Virus

Molecular Biology, Immunosuppression and Pathogenesis of Infectious Bursal Disease Virus

Altaf Hussain1*, Muhammad Saad Ashraf3, Asim Shamim1, Mohsin Nawaz1, Arslan Mehboob2 and Urooj Fatima2

1Faculty of Veterinary and Animal Sciences, University of Poonch Rawalakot Azad Jamu and Kashmir, Pakistan; 2University of Veterinary and Animal Science Lahore, Pakistan; 3THQ Civil Hospital, Daska, Sialkot, Pakistan.

 
*Correspondence | Altaf Hussain, Faculty of Veterinary and Animal Sciences, University of Poonch Rawalakot Azad Jamu and Kashmir, Pakistan; Email: draltafvirk@upr.edu.pk

ABSTRACT

Infectious bursal disease (IBD), caused by infectious bursal disease virus (IBDV), is one of the most devastating and immunosuppressive diseases of the poultry and has been a constraint on the sustainable food security around the globe including Pakistan. Poultry industry is the second biggest industry in Pakistan while IBD is an important disease seriously threatening poultry farming. Despite the use of mass and intense vaccination regimens, the disease continues to sustain in many countries around the globe including Pakistan. However, to some extent, the epidemic strains and epidemic patterns predominant strains of IBDV in Pakistan is unclear. This highlights the need to characterize field strains of IBDV to ascertain the evidence of vaccine failure and to establish foundations for the development of vaccine matching with the epidemic strains.

 

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Hosts and Viruses

June

Vol. 8, Iss. 3, Pages 1-20

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