Atul Sharma, Aruna Chandra Singh, Gautam Bacher, Sunil Bhand
...sed as bacteriostatic or bactericidal agents either to kill or inhibit the growth of microorganisms. Their abuse results in various side effects on the human health, environment and agriculture. The occurrence of bacterial “suprainfection” with tolerance to antibiotics has attracted the significant attention, mainly due to the consequences of multi drug resistance and potential threat to human health and the environment. With the increasing inciden...
Iram Liaqat1*, Najma Arshad2, Muhammad Arshad3, Safdar Ali Mirza4, Nazish Mazhar Ali1 and Ammara Shoukat1
...ration (MIC) and minimum bactericidal concentration (MBC) of plant extracts was also determined. Syzygium aromaticum was proven to have excellent antimicrobial activity against all tested microorganisms, while C. sinensis and M. piperita showed weak antimicrobial activity. Methanolic plant extracts exhibited greater antimicrobial activity than aqueous extracts. Maximum zone of inhibition exhibited by methanolic extracts of S. aromaticum was 10 mm and 20 mm in ...
Hao Gu*, Zhi Yang, Weiqiang Yu, Kan Xu and Yuan-fei Fu*
...evaluated by the minimal bactericidal concentration, change of pH in the first 12 h and OD values of biofilms. Besides, fluorescent images of exopolysaccharides and living bacteria of Streptococcus mutans were measured with confocal laser scanning microscopy (CLSM). In our study, capsaicin showed an outstanding performance in the inhibition of acid producing and biofilm of the four strains of cariogenic bacteria. Meanwhile, low values of MIC of capsaici...
Shahida Sabir1, Anwar Ali Shad1, Tariq Masood1*, Zafar Ali Shah1, Nasiruddin2, Yaseen Ahmad1 and Syed Sartaj Alam3
...of mushroom proved to be bactericidal with highest % inhibition (65, 36 and 75 %) recorded at 25 mg/L concentration against all the three bacterial strains i.e., E. coli, Staphylococcus aureus and Xanthomonas sp., respectively. Maximum % inhibition (about 50%) was recorded at 25 mg/L concentration against all the three fungal species (Penicillium claviforme, Aspergillus flavus and Fusarium sp.). Methanolic extract of P. eryngii showed increasing % mortality ag...
Xiaoli Cai1,2, Saeed Ahmed3, Zhixin Lei1,*, Jianping Wu1,* and Taolei Sun1,2,*
...chanism of bacteria, the bactericidal mechanism of antibiotics, the way of nanoparticles overpasses the cell membrane and approaching the cell, the strategies, prospects and challenges of nanoparticles treating intracellular bacteria.
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Jiang Wu*
... (MIC) value and minimum bactericidal concentration (MBC) value were measured. The virulence gene expression of the four foodborne pathogens was analyzed by quantitative real-time PCR (qRT-PCR). A microplate reader was used to monitor cell growth at 600 nm with 1 h interval. Environmental scanning electron microscope (ESEM) was used to analyze morphological changes of E. coli and Staph. aureus cells. ATP analysis kit and EnSpire microplate reader were used to ...
Faiza Ghazanfar1, Masood Rabbani1*, Aamir Ghafoor2 and Muhammad Hassan Mushtaq3
... study was to define the bactericidal action of organic acids on Campylobacter jejuni, individually and in combination. Total 120 broiler chickens were randomly distributed in ten groups. The groups included negative and positive control, pure organic acid group and commercial organic acid formulation group. Excluding negative control group, all other groups were orally challenged with 0.1 ml of the 6-Log 10 CFU/ml of the Campylobacter jejuni culture in normal...
Hassan A. Aidaros, Eman M. Hafez, Halla E.K. El Bahgy*
... organic matter hindered bactericidal power of many commercial disinfectants such as quaternary ammonium compounds (QUATS), halogen releasing agents including iodine, chlorine and its compounds, but some were not affected, such as glutaraldehyde. Finally, the success of the disinfection process in different poultry farms mainly depends on the selection of suitable disinfectants.
Keywords | Disinfectant, Poultry, E.coli, Pasteurella multocida, Campyloba...
Mai A Fadel1*, Ahmed M Elmahdy1, Jihan Mostafa Badr2, Mohammed AM Saleh3, Mona A.A. AbdelRahman3
...y concentration, minimum bactericidal concentration, and fractional inhibitory concentration were determined. High Performance Liquid chromatography (HPLC) method was developed to quantify the concentrations of enrofloxacin and amoxicillin in serum and different tissues of chickens. The pharmacokinetics and pharmacodynamics indices of both antibiotics were calculated and statistically analyzed. Aspartate aminotransferase, alanine aminotransferase, urea, and cr...
A. Yu. Aliev1*, A.A., Aliev1, A.M. Musaev1, M.Z. Magomedov2
Khasan Khamidovich Shakhbiev1*, Saidkhamzat Saidmagomedovich Abumuslimov1, Larisa. Vakhaevna Taramova1, Islam Khasanovich Shakhbiev1, Svetlana Aleksandrovna Shemyakova2
...effectiveness of the new bactericidal-anthelmintic composition azitroprazifen at a dose of 20 mg / kg body weight with ground beef of in echinococcosis young of dogs complicated by streptococcosis was high in our experience. In all 100% of the experimental dogs, on the 7th day after treatment, there was a complete absence in feces of eggs of E. granulosus and bacteria of the genus Streptococcus and an improvement in the physiological state of the body. In the ...
Tabark F Ahmed, Nibras Z. Yahya*
... highest synergistic and bactericidal effect. It was determined that in vitro study against E. coli O157 in the treatment of urinary tract infection, the combination of ascorbic acid and ciprofloxacin was both more potent and safer than the combination of ascorbic acid and erythromycin. From this study concluded the combination of ciprofloxacin, and erythromycin against isolated E. coli showed that this microorganism is highly sensitive to ciprofloxacin and re...
Iram Liaqat1*, Noor Muhammad1, Muhammad Mubin2, Najma Arshad3, Tehreema Iftikhar4, Sumera Sajjad5 and Farzana Rashid5
...ration (MIC) and minimum bactericidal concentration (MBC) of screened Actinomycetes was in the range of 1.3 - 3.5 mgmL-1 and 1.9 – 4.0 mgmL-1 of bacterial biomass, respectively. Three isolates, S. monticola, S. septentrionalis and S. polaris showed 100 % mortality at 1000 ppm against Anopheles 3rd instar larvae. These findings indicated that actinobacterial isolates possess antibacterial and larvicidal potential. Further extraction and purification of bi...
Orooba Mohammed Saeed Ibrahim1*, Rawaa Saladdin Jumaa2, Nibras Zeyad Yahya1
...ously bacteriostatic and bactericidal against the examined bacteria depending on concentration. Phytochemicals analysis indicated the presence of alkaloids, phenol, saponins, flavonoids, tannins, and glycosides. The test organism was more sensitive to C. limonum compared to C. aurantium. The MICs ranged from 1.56 to 12.5mg/ml; MBCs, (3.125 - 25mg/ml) and MBC/MIC ratios (2.0-4.0). Furthermore, a time killing curve of each 4x MICs and 8x MICs concentrations of j...
Ahmed M. Manthoor, Ali H. Saliem*
...on (MIC) and the minimum bactericidal concentration (MBC), by using 4, 8, 16, 32, 64 and 128 mg/ml concentration of the extract, while 1.562, 3.125, 6.25, 12.5, 25, 50, 100, 200, 400, 800 µg/ml concentration of Ciprofloxacin, on the other hand study mechanism of action of the extract against the same bacteria by Fe-Scanning Electron Microscopic(Fe-SEM). The extraction ratio was (15%) and the phytochemical analysis referred to the presence of alkaloids, f...
UZMA BASHIR,Amna Ali,MUHAMMAD SALEEM HAIDER,Naureen Akhtar
H.A. Abdul-Ratha1*, Sahar Mahdi Hayyawi2, Essam F. AL-Jumaily3
... formation important for bactericidal activity against cell membrane with highly potent for the treatment against Staphylococcus aureus infection. In addition, the treatment with combination between acidocin and biofilm lead to lysis of cytoplasm, nucleic acid destruction, disappearance and vacuolization in Staphylococcus aureus cells. The treatment with combination between acidocin and biofilm lead to lysis of cytoplasm, nucleic acid destruction, disappearanc...
