Therapeutic Effect of Red Ginger Leaf Ethyl Acetate Fraction Gel on Staphylococcus aureus-Infected Excision Wounds on Rat: A Preclinical Study
Bunga Rimta Barus1, Masfria Masfria2*, Aminah Dalimunthe3, Sovia Lenny4
1Doctoral Program, Faculty of Pharmacy, Universitas Sumatera Utara, Medan, Indonesia; 2Departement of Chemistry Pharmacy, Faculty of Pharmacy, Universitas Sumatera Utara, Medan, Indonesia; 3Departement of Pharmacology, Faculty of Pharmacy, Universitas Sumatera Utara, Medan, Indonesia; 4Departement of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Sumatera Utara, Medan, Indonesia.
*Correspondence | Masfria Masfria, Departement of Chemistry Pharmacy, Faculty of Pharmacy, Universitas Sumatera Utara, Medan, Indonesia; Email:
[email protected]
Figure 1:
Thin Layer Chromatogram in UV 366.
Figure 2:
Graph of antibacterial activity test of gel preparation. Asterisk *P ≤ 0.05; **P ≤ 0.01; *** P ≤ 0.001; ****P ≤ 0.0001 represents significant differences to positive control group and NS represents not significant (P > 0.05).
Figure 3:
Histopathology of Epidermal Thickness, A: Group 1; B: Group 2; C: Group 3; D: Group 4; E: Group 5; F: Group 6.
Figure 4:
Angiogenesis histopathology test results of the treatment group.