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Therapeutic Effect of Red Ginger Leaf Ethyl Acetate Fraction Gel on Staphylococcus aureus-Infected Excision Wounds on Rat: A Preclinical Study

Therapeutic Effect of Red Ginger Leaf Ethyl Acetate Fraction Gel on Staphylococcus aureus-Infected Excision Wounds on Rat: A Preclinical Study

Bunga Rimta Barus1, Masfria Masfria2*, Aminah Dalimunthe3, Sovia Lenny4

1Doctoral Program, Faculty of Pharmacy, Universitas Sumatera Utara, Medan, Indonesia; 2Departement of Chemistry Pharmacy, Faculty of Pharmacy, Universitas Sumatera Utara, Medan, Indonesia; 3Departement of Pharmacology, Faculty of Pharmacy, Universitas Sumatera Utara, Medan, Indonesia; 4Departement of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Sumatera Utara, Medan, Indonesia.

 
*Correspondence | Masfria Masfria, Departement of Chemistry Pharmacy, Faculty of Pharmacy, Universitas Sumatera Utara, Medan, Indonesia; Email: masfria@usu.ac.id

Figure 1:

Thin Layer Chromatogram in UV 366.

Figure 2:

Graph of antibacterial activity test of gel preparation. Asterisk *P ≤ 0.05; **P ≤ 0.01; *** P ≤ 0.001; ****P ≤ 0.0001 represents significant differences to positive control group and NS represents not significant (P > 0.05).

Figure 3:

Histopathology of Epidermal Thickness, A: Group 1; B: Group 2; C: Group 3; D: Group 4; E: Group 5; F: Group 6.

Figure 4:

Angiogenesis histopathology test results of the treatment group.

Pakistan Journal of Zoology

August

Pakistan J. Zool., Vol. 56, Iss. 4, pp. 1501-2000

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