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Mutational and Evolutionary Analysis of Interleukin-2 Gene in Pakistani Goat Breeds

Mutational and Evolutionary Analysis of Interleukin-2 Gene in Pakistani Goat Breeds

Tanveer Hussain1, Abdul Wajid1, Jabbar Khan2, Asif Nadeem1, Misbah Hussain1, Qurat ul-Ain1 and Masroor Babar1*

1Department of Molecular Biology, Virtual University of Pakistan, Lahore, Punjab, Pakistan
2Institute of Biological Sciences, Gomal University, Dera Ismail Khan, Pakistan
 
* Corresponding author: [email protected]

Fig. 1.

Transversion substitution of single nucleotide (T→A) observed in the non-coding region of IL-2 gene in multiple sequence alignment of Dera Din Panah (A), Nachi (B), Kamori (C) and Beetal (D) goat breed. Rectangular box is showing site of polymorphism.

Fig. 2.

A, Phylogenetic tree generated by simple agglomerative hierarchical clustering method UPGMA showed that avian and mammal were making two distinct groups in phylogenetic tree. B, Percent Identity Matrix of interleukin-2 protein in 10 genera including Capra.

Pakistan Journal of Zoology

October

Pakistan J. Zool., Vol. 56, Iss. 5, pp. 2001-2500

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