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Hepatoprotective Effects of Tamarix dioica Leaf Extracts on Paracetamol-Induced Hepatotoxicity in Mice

Hepatoprotective Effects of Tamarix dioica Leaf Extracts on Paracetamol-Induced Hepatotoxicity in Mice

Tahani Ahmad Al-Matrafi1, Zuhair M. Mohammedsaleh2, Mamdoh S. Moawadh2, Waheeb S. Aggad3, Rawabi Mohamed almuhimed4, Zamzam Alhuwaymil5, Aishah E Albalawi6, Ifat Alsharif7, Hailah M. Almohaimeed8, Fatima S. Alaryani9 and Mona H. Soliman10,11*

1Anatomy Department, College of Medicine, King Saudi University, Saudi Arabia
2Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences,University of Tabuk, Tabuk 71491, Saudi Arabia
3Department of Anatomy, College of Medicine, University of Jeddah, P.O. Box 8304, Jeddah23234, Saudi Arabia
4Saudi Authority for Intellectual Property (SAIP), Saudi Arabia
5Organic Department, College of Science and Humanities at Al-Quway’iyahl, Shaqra University, Saudi Arabia
6Faculty of Science, Department of Biology, University of Tabuk, Tabuk 47913, Saudi Arabia
7Department of Biology, Jamoum University College, Umm Al-Qura University, 21955, Makkah, Saudi Arabia
8Department of Basic Science, College of Medicine, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia
9University of Jeddah, College of Science, Department of Biological Sciences, Jeddah 21589, Saudi Arabia
10Botany and Microbiology Department, Faculty of Science, Cairo University, Giza 12613,Egypt
11Biology Department, Faculty of Science, Taibah University, Al-Sharm, Yanbu El-Bahr,Yanbu 46429, Kingdom of Saudi Arabia
 
*      Corresponding author: [email protected]

Fig. 1.

Effect of leaf extract of Tamarix dioica on liver function enzyme (AST, ALT and ALP) total bilirubin and total protein (A), kidney biomarkers (albumin, triglycerides, Urea, creatinine, total cholesterol, TNF α, COX-2 and IL-6 in control and different group of albino mice.

Fig. 2.

Effect of leaf extract of Tamarix dioica on liver section in control and treated groups.

Fig. 3.

Effect of leaf extract of Tamarix dioica on analysis of Inflammation and Fibroblast score among the control and treated groups.

Equation 1

Pakistan Journal of Zoology

October

Pakistan J. Zool., Vol. 56, Iss. 5, pp. 2001-2500

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