Genotoxic Effect of Pesticides on Perna viridis
Genotoxic Effect of Pesticides on Perna viridis
Nafisa Shoaib* and Aisha Majid Ali
ABSTRACT
Genotoxicity is considered as one of the endpoints in assessing toxic effect of pollution. In the present study genotoxic effects of pesticides in the Perna viridis have been evaluated by the induction of micronuclei (MN). The aim of the present study was to assess the MN frequency in the haemolymph of green mussel (Perna viridis) after exposure to different concentrations of organophosphate pesticides (chlorpyrifos, malathion), synthetic pyrethroid pesticide (cypermethrin, lambda-cyhalothrin) and herbicide (buctril). Haemocytes of bivalve play an important role in immune defense and detoxification of contaminants. The bivalves were exposed to different concentrations of test pesticides in a static system. The MN frequencies of all the pesticide treated mussel groups increased significantly (p< 0.05) until the end of the exposure period as compare to control. The highest MN frequencies were recorded after cypermethrin exposure on day 12 (7, 8.5 and 11‰ for 0.5 ppm, 1 ppm and 1.5 ppm concentrations respectively) in haemolymph. However the lowest MN frequencies were recorded after buctril exposure (3.5, 3.5 and 5‰ for 0.5 ppm, 1 ppm and 1.5 ppm concentrations, respectively) in haemolymph. The use of haemocytes of green mussel (Perna viridis) in MN assay proved to be a sensitive tool for the assessment of genetic damage.
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June 2022
Vol. 54, Iss. 3, Pages 1001-1500
