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Effect of Pulmonary Rehabilitation Combined with Tiotropium Bromide on BODE Index in Clinical Stable Patients with Chronic Obstructive Pulmonary Disease

Effect of Pulmonary Rehabilitation Combined with Tiotropium Bromide on BODE Index in Clinical Stable Patients with Chronic Obstructive Pulmonary Disease



Affiliated Hospital, Changchun University of Chinese Medicine, Changchun, 130021, China

*      Corresponding author: m13578691601@163.com

ABSTRACT

This paper observes the effect of pulmonary rehabilitation combined with tiotropium bromide on BODE index in clinical stable patients with chronic obstructive pulmonary (COPD) disease. For this purpose, a retrospective cohort was designed. In this work, 200 patients with COPD at stable stage were enrolled as research subjects. They were divided into the control group (n=100) given conventional treatment (bronchodilator, antioxidant, expectorant antitussive) and the research group (n=100) given pulmonary rehabilitation combined with tiotropium bromide treatment. The BODE indexes of two groups were compared and observed at 4 and 8 months of follow-up. After four months the research group showed significant improvement in dyspnea, 6MWD, FEVl% pred, BMI and BODE index, p<0.05. At eight months of treatment, the improvement was sustained for all outcomes at the research group, at p<0.05. Pulmonary rehabilitation combined with tiotropium bromide therapy for clinical stable patients with COPD can produce significant improvement in patients’ BODE index.
 

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Pakistan Journal of Zoology

December

Vol. 53, Iss. 6, Pages 2001-2521

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