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Effect of Congrong Tusi Pill on Ovarian Artery Blood Flow and Sex Hormones in Adjuvant Treatment of Ovarian Function Decline

Effect of Congrong Tusi Pill on Ovarian Artery Blood Flow and Sex Hormones in Adjuvant Treatment of Ovarian Function Decline

Jianmin Liu1, Jiancheng Zhang2, Peijuan Wang3,* and Moslem Lari Najafi4

1Department of Obstetrics and Gynecology, Huai’an TCM Hospital Affiliated to Nanjing University of Chinese Medicine, Huaian 223001, China
2Department of Traditional Chinese Medicine, Lianshui County People’s Hospital, Huaian 223400, China
3Department of Obstetrics and Gynecology, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing 210028, China
4Pharmaceutical Sciences and Cosmetic Products Research Center, Kerman University of Medical Sciences, Kerman, Iran
 
Jianmin Liu and Jiancheng Zhang contributed equal to this article as co-first author.
 
* Corresponding author: wangpeijuan999@163.com

ABSTRACT

The present study was aimed to investigate the effect of new addition congrong tusi pill on ovarian artery blood flow and sex hormones in the adjuvant treatment of ovarian function decline. Ninety patients with ovarian function decline were randomly divided into 3 groups: new addition congrong tusi pill treatment group (n=30 cases), diethylstilbestrol treatment group (n=30 cases) and the control group (n=30 cases). A comparative analysis is made on sex hormone levels, ovarian artery blood flow, ovarian volume and number, treatment efficacy, glucose metabolism, ovulation and fertility in each group. There are statistical differences in sex hormone level, ovarian arterial blood flow, ovarian volume and number, treatment efficacy, glucose metabolism, ovulation and fertility in each group (P<0.05). The total effective rate of new addition congrong tusi pill is 100.00% for ovarian function decline, while that of diethylstilbestrol treatment is only 83.33%, and new addition congrong tusi pill group shows better recovery in each index compared to diethylstilbestrol, with patients’ ovarian function greatly improved. To conclude, new addition congrong tusi pill has better clinical effect in improving ovarian artery blood flow and sex hormone levels than diethylstilbestrol in adjuvant treatment of ovarian function decline, which is worthy of clinical popularization and use.

 

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Pakistan Journal of Zoology

December

Vol. 54, Iss. 6, Pages 2501-3000

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