Cholangiocarcinoma with Multiple Organ Metastasis in a Captive Puma (Puma concolor)
Cholangiocarcinoma with Multiple Organ Metastasis in a Captive Puma (Puma concolor)
Ho-Seong Cho1 and Yeonsu Oh2,*
Peritoneal organs of Puma concola. Gross pathological findings exhibited yellowish tumor masses of varying sizes in the liver (A), diaphragm (B), lungs (C), and kidneys (D).
Puma concola. Papillary growth pattern of the adenocarcinoma cells in the liver (A and B), heart (C) and kidney (D). H&E. Scale bar=25 um (A inset), 50 um (B, D inset), 100 um (A,C) and 200 um (D).
Puma concola. Cytoplasmic immunoreactivity for cytokeratin pan type I (AE I). DAB chromogen, hematoxylin counterstain. Scale bar=50 um.