Farhat Ijaz1, Rana Khurram Aftab2*, Samia Jawed3
...-reactive protein (CRP), interleukins 6 (1L-6) and tumor necrosis factor alpha (TNF-α). Relation of TNF-α with obesity induced IR and T2DM is unclear as results obtained from different studies are very controversial.
Objective: This study was designed to compare TNF-α levels and insulin resistance in obese and non-obese type 2 diabetics.
Methodology: A cross sectional comparative study was conducted in di...
Farah Abid1,2, Mohammad Saleem1,3*, Tahir Maqbool4, Tania Ahmed Shakoori5, Faheem Hadi4, Tahir Muhammad4, Saira Aftab4, Yasir Hassan7 and Shabana Akhtar4,6*
... different cytokines and interleukins involved in inflammation. Real-Time PCR results showed a down-regulation of TNF-α, COX-2, IL-6, IL-1β, NF-κβ1and up-regulation of IL-4, IL-10 and I-κB genes. Levels of antioxidants, superoxide dismutase and catalase were determined to be significantly higher (p<0.05) in the group treated with E-AM compared to the arthritic group. In addition, histopathological examination indicated reduction ...
Maysaa A. Jumaah*, Ali A. Al-Iedani
... (interferon γ and interleukins (IL)-12) and anti-inflammatory cytokines (IL-4 and IL-10) and innate immune responses (total white blood count, phagocytosis and respiratory burst). Our results demonstrated that all vaccines have induced both innate and adaptive immune responses. However, the adjuvant with alum hydroxide mixed with sonicated antigens and killed bacteria induced higher pro-inflammatory cytokine effects (IFN- γ P ˂ 0.05, P <0.0 1)...
Emad M. Gad1, Haidy G. Abdel-Rahman2, Mohy Eldin Abd-El-Fattah1, Merna M. Kamal1, Ahmed Shaker Eltahan3, Amina A. Dessouki3*
...lberry, Glucose, Kidney, interleukins, RT-PCR, western blot, inflammation, oxidative stress, SGLT2 inhibitors.
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