Bushra Niaz1,*, Tahir Zahoor1, Muhammad Atif Randhawa1 and Amer Jamil2
...crobial, antioxidant and immunomodulatory as well as a number of other biological functions. Its potential can be exploited in several food applications. Keeping in view the increased demand of natural antimicrobial agents to control prevalence of food borne pathogens in final packaged food products as well as for food preservation/ biocontrol, this study was designed to isolate lactoferrin from milk of camel. Cation exchange resin (CM-Sephadex C-25) was used ...
Ali Raza Jahejo1,2, Nasir Rajput2, Wen-xia Tian1,*, Muhammad Naeem2, Dildar Hussain Kalhoro2, Asmatullah Kaka2, Sheng Niu1 and Fa-jie Jia1
...ucted to investigate the immunomodulatory and growth promoting effects of basil (Ocimum basilicum) and ascorbic acid in heat stressed broiler chicken. A total of 360 (Hubbard) one-day old broilers were reared under heat stress (38 ± 1°C) and randomly divided into three groups i.e. A, B and C as control, basil seed at 5g/kg and ascorbic acid at 200 mg/kg supplementation, respectively. Improvement of intestinal villus seen in basil suppl...
Shaukat Ali1,*, Sadia Batool2, Fatima Javed Butt2, Sundas Nasreen1, Hafiz Muhammad Tahir1
...they have antioxidative, immunomodulatory, antipathogenic and anti-cancerous properties. Review based on the futuristic and modern aspects of cancer treatment, we believe that probiotics based cancer treatment would be supportive to overcome the chemotherapeutic and radiological drawback sand provides an appropriate cancer treatment strategy. Anticipating various challenges, we expect that probiotics may become a potential cancer bio-theranostic in the field o...
Muhammad Rehan3, Asim Aslam3, Javeria Umber4, Muti-ur-Rehman Khan3, Waqar Azeem3, Hassan Aftab5, Ahsan Anjum3, Muhammad Abid6, Abdul Hameed Khan3, Hafiz Hasnain Ayoub5, Altaf Hussain2 and Muhammad Farooq Khalid1*
...es revealed the putative immunomodulatory role of 1,25(OH)2D3 besides its classical role of maintaining phosphorus and calcium metabolism inside body. Vitamin D is involved in homeostasis of innate and adaptive immune responses by modulating activity of monocytes, dendritic cells, macrophages and activation of T and B lymphocytes. Vitamin D modulates cytokine response and anti-microbial peptides (AMPs) production which boost innate immune response. Hypovitamin...
Rabia Riaz1, Khushi Muhammad1*, Masood Rabbani1, Muhammad Amjad Iqbal2, Aamir Riaz Khan2, Sadia Sarfaraz1, Mudassar Naseer3 and Khalid Majeed1
...at NDV has insignificant immunomodulatory effect on antibody response of birds to the MG vaccine.
... 
Lungile Gumede1,2, Thobela L. Tyasi1, Teedzai Chitura1*, Khanyisile R. Mbatha3
...y aimed to ascertain the immunomodulatory effects of Moringa oleifera (M. oleifera) leaves supplemented to the diets of wether BaPedi goats following vaccination with blanthrax vaccine. Twelve clinically healthy BaPedi goats with an average body weight of 19 ± 1.47 kg and an average age of 11±0.26 months were randomly selected from the flock at the University of Limpopo experimental farm. The experiment was conducted in three phases which are ada...
Hairul Islam M. Ibrahim1,2, Abdalla A. Sayed1,3, Abdel Naser A. Ahmed4,5 and Emad A. Ahmed*1,6
...designed to evaluate the immunomodulatory properties of pinocembrin (PCB) and the anti-apoptosis effects using in vitro and in vivo mice splenocytes and experimental autoimmune encephalomyelitis (EAE) in C57BL/6j female mice, respectively. The reduction of clinical symptoms and disease index were evaluated by histochemical analysis. T-cell population and cytokines levels in myelin oligodendrocyte glyco-protein (MOG) challenged PCB treated cells were estimated ...
Ahmed Ali Chandio1, Asghar Ali Kamboh1*, Nazar Ali Korejo2, Riaz Ahmed Leghari3 and Muhammad Ali Chandio4
...ion aimed to explore the immunomodulatory and gut microflora modulatory effects of dietary P. pinnata in broilers. Day old broiler chicks (n=125) were purchased from local hatchery and equally divided into the five groups, i.e., C (control) that offered basal diet, while, T1, T2, T3 and T4 groups were supplemented 0.5, 1, 1.5 and 2% P. pinnata leaf powder (PPLP) in basal diet respectively. The experimental groups were observed for the performance parameters, a...
Anhar Ibrahim Elhanafy*, Amr Mohamed Mousa, Amaal Mohamed Kamal
Azza M. El-Kattawy1, Tarek Abou Zed1, Randa Megahed1 and Mohammed El-Magd2*
...ulated the expression of immunomodulatory genes [interferon gamma (IFNγ) and lactoferrin (LF)], 2) decreased the expression of inflammation-related genes [tumor necrosis factor alpha (TNFα) and interleukin 1 beta (IL1β)], 3) declined the expression of matrix metalloproteinase-3 (MMP3), transforming growth factor beta (TGFβ), and oxidized-LDL receptor (OLR1), 4) upregulated the expression of the anti-inflammatory gene IL10, 5) reduced the ...
Sajida Batool, Iqra Ashraf, Shafaat Yar Khan, Sitara Shameem* and Breha Kazmi
...was investigated for its immunomodulatory potential in vitro using T-lymphocytes. Phytohaemagglutinin (PHA) st https://researcherslinks.com/journals imulated T-lymphocytes were treated with extract of C. procera (1, 2, and 4 µg/mL) for 4, 8, 12, 24, and 48 h. Levels of pro-inflammatory cytokines (Interleukin-6 and Interleukin-8) were measured after 8, 12, and 24 h while levels of anti-inflammatory cytokines (Interleukin-10) were measured after 4 and 48-h...
Rahib Ali Chachar1, Asghar Ali Kamboh1* and Manatbai Bakhetgul2
... individual and combined immunomodulatory and gut microflora modulatory effects of moringa and neem leaf powder in Japanese quails. A total of eighty (80) unsex day-old Japanese quail chicks were distributed into the four groups. The T0 offered only a basal diet, while T1, T2 and T3 were supplemented with moringa (5%), neem (1%) and moringa (5%) + neem (1%) leaf powder respectively in the basal diet. Results showed that live body weight and carcass weight were...
Feri Eko Hermanto1, Yuli Frita Nuningtyas1, Filoza Marwi1, Fajar Shodiq Permata2, Agus Susilo1, Muhammad Halim Natsir1*
...immunity and explore the immunomodulatory potential of bioactive compounds found in these herbs. Biological networks were constructed for gut health and mucosal immunity, focusing on common proteins to identify promising targets. Our analysis pinpoints Interleukin-6 (IL-6) as the central protein governing gut health and mucosal immunity. Further exploration reveals that several bioactives, primarily from Teak Leaves and Ginger, form tight interactions with IL-...
Samia S. Alkhalil1, Faisal Al-Sarraj2, Abeer S. Aloufi3, Zuhair M. Mohammedsaleh4, Mamdoh S. Moawadh4, Fayez M. Saleh5, Majid Al-Zahrani6, Waheeb Aggad7, Youssef S. Alghamdi8, Mutaib M. Mashraqi9, Saleh Alshamrani9 and
Mona H. Soliman10,11*
Marah Salim Hameed1, Ali Ibrahim Ali Al-Ezzy2*
...nt, nephroprotective and immunomodulatory activity of vitamins C and E -sodium selenite in mice intoxicated with sodium nitrate. Thirty healthy adult male mice of 25-30gm body weight divided randomly into six groups (5 mice/each) administered the following daily for 2 weeks, respectively: Vitamin E -sodium selenite 0.5 ml/LDW(T1); vitamin C (0.5 gm/L (T2); NaNO3 0.5gm/L (T3); NaNO3 (70 mg/kg) and vitamin E -sodium selenite 0.5 ml/L (T4); NaNO3 [70 mg/kg and vi...
