Rana Hanan1*, Muhammad Waqar Shafi1, Sumair Anwar2 and Numrah Nawaz1
...es), three students were hypertensive, 55 pre-hypertensive and 42 normotensive; among pre-hypertensive female students were more in number as compared to male students. Mean age was 21.6 years with increased frequency of pre hypertensive and hypertensive individuals in the first, second and final year class. A total of...
Sana Qanber Abbasi1*, Ejaz Ahmed2 and Rabia Sattar1
... between migraineurs and hypertensive migraineurs. It was a cross sectional comparative study in which serumpro BNP levels were measured in migraine patients and hypertensive patients with migraine. A blood sample of 3 cc was drawn from the median cubital vein after securing aseptic measures. The blood sample was allowed to clot for 30 minutes and serum was separated. The serum was then centrifuged andpro BNP levels were est...
Boxin Dou, Ying Liu*, Yumeng Liu, Lili Fan, Yongqiang Ma, and Yanguo Shi
... selected commercial antihypertensive pharmaceutical. A new peptide with ACE inhibition properties was obtained by using alkaline protease to enzymatic hydrolysis of RB crude protein purified by ultrafiltration, size exclusion chromatography and RP-HPLC. Using consecutive chromatographic techniques successively, the acidic hydrolysates of RB proteins were fractionated and the new ACE inhibitory triplet was isolated and identified. The amino acid sequence of th...
Sara Zafar* and Asmatullah
...t of a commonly used antihypertensive drug, atenolol during gestation and ameliorative effect of pomegranate juice against its toxicity. Dose was administered to pregnant mice by gavage. The high dose contains Atenolol 2.5 µg/g body weight (B.wt.) of treated mice and low dose contains 1.65 µg/g B.wt. The dose was administered from the 6th -12th day of the gestation period for seven days. Many congenital abnormalities including hemorrhages, hygromas...
Fahrauk Faramayuda1,2*, Totik Sri Mariani3, Elfahmi1,4 and Sukrasno1
...erial, antidiabetic, antihypertensive anti-inflammatory. The country of Indonesia has three varieties of O. aristatus, namely purple, white-purple and white. The purple and white-purple population has started to decline. Efforts are needed to maintain the two varieties’ population, one of which is plant tissue culture. It is hoped that in vitro cultured plants contain the same secondary metabolites as the wild type. This study aims to identify the chemic...
Rukhsana Anwar1*, Muhammad Usman Khalil1 and Kanwal Ashiq1,2
...acute and sub-acute anti-hypertensive effect of methanolic extract of Colebrookea oppositifolia leaves. The sub-acute anti-hypertensive activity of a methanolic extract of Colebrookea oppositifolia 250 mg/kg were studied for 14 days in rats. Captopril (20 mg/kg) was given as a standard control. Non-invasive blood pressure (NIBP) monitoring technique was used to assess the blood pressure of rats. The frequency of hippuric aci...
Umara Amir ud Din1, Waqas Ahmed Khan1*, Khurrum Shahzad1,2, Basharat Ali3, Misbah Hussain1,4 and Fazli Rabbi Awan4
...hway and target for anti-hypertensive drugs. ACE (I/D) polymorphism studies for its association with kidney function and risks of DN have been reported in different populations but with varying results. Hence, the objective of current study was to study the association of ACE (I/D) polymorphism with risk of DN in Pakistani subjects. For this study, 702 subjects were recruited who were divided into three groups; healthy control (n=222), diabetics without nephro...
Youlin Fu1, Zhongming Yang1 and Chongrong Qiu2*
...e cells of spontaneously hypertensive rats. Eight healthy male spontaneously hypertensive rats (hypertension group) and 8 normal rats (Wistar group) were selected, and CA smooth muscle cells were isolated from the two groups. The PC of CA smooth muscle cells were recorded by patch clamp whole cell recording technique, and the BK currents and BK tail currents of CA smooth muscle cells were recorded and compared between the tw...
