Search for Glucagon

Effects of Oral Glucose Administration on Plasma Biochemical Parameters, Insulin, and Hepatic Metabolic Enzymes Activities in Golden Pompano (Trachinotus ovatus)

Chuanpeng Zhou¹, Heizhao Lin^2,*, Zhong Huang², Jun Wang¹, Yun Wang¹ and Wei Yu²

...e group has lower plasma glucagon content 12 h after oral administration, higher muscle and hepatic glycogen contents 6 h after oral administration (P<0.05). The hepatic pyruvate kinase activity peaked 6 h after oral administration in both doses of glucose groups and thereafter started to decrease 24 h after oral administration. While the hepatic PEPCK and G6Pase activities decreased 9 h after oral administration in both doses of glucose groups and then ret...

Antidiabetic Efficacy of Zinc Oxide Nanoparticles and Empagliflozin Combinations

Saydat Saad Abd El-Megeed1, Walaa Yehia El-Sayed1*, Tarek Khamis2

... 1 (IGF1), PPAR-α, glucagon-like peptide 1 (GLP-1) in pancreatic homogenate, and peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α) in pancreatic homogenate which is also a dose- and time-dependent manner. Thus, the study has demonstrated that the combination of Empagliflozin and ZnO NPs could be a promising therapy to alleviate the progression of diabetes.

Keywords | ZnO nanoparticles; Diabetes mellitus;

Evaluation of Arabian Camels Milk’s Ability in Ameliorating Glucose Homeostasis in STZ-induced Diabetes in Adult Male Rats

Ali Mosa Rashid Al-Yasari1, Zahid I. Mohammed2, Haider S. Almnehlawi3,4, Ali F Bargooth5, Nawar Jasim Alsalih1, Huda F. Hasan6*, Mohenned A Alsaadawi1

...od glucose, insulin, and glucagon. Animals were sacrificed on day 28, and tissues were collected for immunohistochemical identification of pancreatic cells that produce insulin and glucagon. Based on our results, none of the research parameters significantly differed across the groups on day 0. Days 1 through 28 showed that STZ-Diabetes group had the uppermost blood glucose level with lowermost blood insulin among the study ...

2,4 -Dinitrophenol Trans-Differentiate NIH3T3 Cells into Insulin Producing β-Cells

Shumaila Usman^1,2, Irfan Khan², Kanwal Haneef³ and Asmat Salim²*

...Nkx 6.1, Pdx-1, insulin, glucagon, somatostatin and Sca-1) at gene and protein levels. In the presence of DNP, NIH3T3 cells appeared round, small and contracted while after reoxygenation they regained the normal fibroblast like spindle shaped morphology. The strategy to induce efficient transdifferentiation of NIH3T3 cells into IPCs has shown positive endocrine expression pattern, specifically β-cell specific transcription factors, demonstrating their suc...