Umair Riaz1*, Muhammad Ali Kharal2, Ghulam Murtaza3, Qamar uz Zaman4, Sana Javaid4, Hina Ahmed Malik3, Humera Aziz3 and Zafar Abbas1
...as osmotic and oxidative anxiety. The most effective mechanism is the biosynthesis of secondary metabolites at cellular level which included organic compounds that help plants to cope with stress conditions by reducing the intensity of stress through enhancing antioxidants activities, detoxifying toxic ions, regulating the uptake of nutrients and by mediating the transport and distribution of different hormones. Caffeic acid is actively involved in plant physi...
Jennifer Mei Sze Ang
...perienced as feelings of anxiety and angst, and experiences of hostility as we encounter others through their gaze and objectification. From this framework, it examines and reflects on both the empirical models of well-being focused on desire/satisfaction/positive emotions and the eudaimonic strands of well-being studies emphasizing autonomy. It shows that the strand of well-being which places good mood and satisfaction as central goals of a happy life are pro...
Rafia Sadaf1, Ishrat Younus2*, Sidra Maqbool2, Talha Bin Fayyaz3, Sarah Jameel Khan1, Sidra Siddique1 and Rida Fatima1
... acute toxicity and anti-anxiety activity of ethanol extract of Pulsatilla nigricans leaves. The acute oral toxicity shows that, plant extract up to 5000 mg/kg produces no signs and symptoms related to toxicity and also no mortality was observed. Antianxiety activity of Pulsatilla nigricans was examined by using elevated plus-maze paradigm and hole-board paradigm in rats at two different doses i.e. 250 and 500 ...
Yan Wen1, Liu Lian2, Zhuang Xun3, Murong Jiaying4, Cui Shuyi1, He Wanwen1, Mai Guanghuai5, Huang Wenzhu1, Chen Gang1,* and Wang Zhijun1,*
...mptoms of depression and anxiety, enhanced rehabilitation outcomes, and promoted quality of life. Thus, it was suggested as an effective auxiliary exercise rehabilitation method.
... 
Hamida Sarwar1, Kousar Perveen1,Rida Mazhar2, Muhammad Afzal1, Syed Amir Gilani3
...s focused on depression, anxiety, distress, and insomnia using the Chinese genre of authorized measurement tools. Removed reference statistical evaluation was performed by using SPSS version 2.6. The data was analyzed to assess the severity of symptoms of depression, anxiety, distress, and insomnia; and then conferred as numbers and percentages. A significant proportion of doctors, nurses, and paramedics reported symptoms of...
Juweria Abid1, Hooria Latif2, Amir Sohail2, Saroosh Fatima Tahir Syed2, Shakeel Ahmad3, Tooba Asif4 and Muhammad Farooq5*
...ge of about 78.4%. Their anxiety about body weight and shape was also found to be higher (56.9%). Overall, the ratio of smoking in students was less but it predominated in male students. And majority of students (40.7%) were having a sedentary lifestyle while 40.4% with moderate physical activity. SCOFF questionnaire results showed 90% of positive results while the 10% of the population need further examination. The collected data results were mostly positive ...
Maher Mohammed Yousef Alobaysi,1,4 Turki Albacker2, Waleed Alharbi2, Osama Almogbel2, Sadik Mohammed3, Fahad Al-Abbasi4, Vikas Kumar5 and Firoz Anwar4*
... set of study, free from anxiety and were not on any medication before enrollment of study. Cortisol and white blood cells (WBC) count showed a significant difference in pre and post catherization procedures. Significant (P˂0.05) linear correlation was found between pre and post values for heart rate, WBC, electrolytes, blood urea nitrogen (BUN), cortisol, tri-iodothyronine, thyroxine, thyrotropin and Vit D in paired sample correlation. WBC counts measured be...
Farah Naz1*, Asad Umair2 and Ghazala Noureen3
...uncertainty. As fear and anxiety built up, governments around the world responded to the pandemic by imposing long, nationwide lockdowns in an attempt to “flatten the curve”-a term that refers slowing down the spread of the disease in order to prevent healthcare facilities from being overwhelmed by too many new patients. However, lockdowns and related strategies designed to minimize the spread of the pandemic, like early detection, isolation of con...
Shabana Noureen1, Shirmeen Ijaz2, Saad Ullah3, Iqra Shafique Abbasi4 and Shakeel Ahmad5*
...d major themes of social anxiety discussed on Twitter A qualitative research design was used in the current research. NCapture was used to randomly select 500 tweets of social anxiety published from 1st January 2022 to 30th June 2022. Nvivo was used to do a content analysis of tweets. The content analysis reflected three major symptoms of social anxiety including behavioural, cognitive, an...
Safaa Rhaimi1, Sara Brikat2, Mouloud Lamtai2*, Mohammed Ouhssine1
...nd of the experiment for anxiety-like and depression-like and memory. Accordingly, treatment with salvia officinalis essential oil at a dose of 2000 mg/kg showed no mortality or clinical signs, nor any changes in body, organ weights or biochemical parameters, except for mortality induced in one female rat treated with 2000 mg/kg. Furthermore, the LD50 (50% lethal dose) was determined at 3000 mg/kg. Based on these findings, the no observed adverse effect level ...
Oussama Zghari*, Mouloud Lamtai, Sofia Azirar, Mohamed Yassine El-Brouzi, Hajar Benmhammed, Aboubaker El-Hessni, Ali Ouichou, Abdelhalem Mesfioui
...y showed that Al induced anxiety and depressive-like behaviour and cognitive impairment. In the hippocampus, Al also increased the levels of lipid peroxidation (LPO) and nitric oxide (NO) and reduced the activity of superoxide dismutase (SOD) as well mediates brain damage in CA3 hippocampal area. These alterations were reversed by MEL. It can be concluded that, by exerting its properties against the oxidative action of this metal in the hippocampus, MEL may pl...
Sarwat Yousuf1, Shaista Emad2 , Mohammad Misbah ur Rehman3, Zehra Batool4, Sara Qadeer5, Yousra Sarfaraz1, Sheeza Sheikh1, Sana Sadaf6 and Tahira Perveen1,*
...ts showed depression and anxiety-like effects, and impaired muscular strength. Altered brain antioxidant enzyme activity and elevated corticosterone in plasma were also observed in rats treated with a high dose of lemon peel oil. The present study demonstrates that a low dose of lemon peel oil has a potential therapeutic effect on psychological functions following 14 days of oral administration in rats. Lemon peel oil could be considered for therapeutic use ag...
Aneela Ahmed Tagar1*, Mahvish J. Channa2, Kanwal Ahmed Tagar3 and Kaka Kainat4
...uring COVID-19 including anxiety and depression. Additionally, Biomarkers remained increase in patients (i.e, ferritin, D- dimer, CRP, LDH and CBC was slightly altered in subjects. Lastly, Troponin levels were normal among survivors. The conclusion of present research is that COVID-19 impacts overall health of patients including; long lasting symptoms, malnutrition, anxiety, depression and alterations in Biochemical markers ...
Amna Mushtaq, Asia Bibi* and Nahid Kausar
...ients. The prevalence of anxiety (61.8% vs. 18.7%), depression (56.9% vs.15.3%), sleep apnea (35.3% vs. 6.7%), eating disorders (18.1% vs. 1.3%), marital maladjustment (27.5% vs. 5.3%), poor quality of life (35.3% vs. 3.3%) and migraine (55.4% vs. 10.7%) was significantly high in PCOS women as compared to controls (p<0.001). Infertility was significantly linked to psychotic implications and PCOS female (p<0.001). So, infertile PCOS patients were more dep...
Frequency of Non-Motor Clinical Features of Parkinson Disease and the Associated Factors in Pakistan
Jaiperkash Moolchandani1*, Geeta Moolchandani2, Syed Mohsin Turab3, Nasima Iqbal4, Ambreen Rehman5 and Shaima Sultana Memon6
...al symptoms, depression, anxiety, and apathy are the most prevalent symptoms. Although these are treatable but usually are not recognized at early stage in Parkinson’s disease, so the current study aimed to find out the prevalence of non-motor clinical symptoms and the associated factors. A descriptive cross-sectional study was conducted at the Neuro-medicine Ward, (28), Jinnah Postgraduate Medical Center, Karachi during August 2019 to February 2020. Dem...
Abdeljabbar Nassiri1, Mouloud Lamtai1*, Inssaf Berkiks1,2, Hajar Benmhammed1, Sidi Mohamed Coulibaly1,3, Miloud Chakit1, Laila Ibouzine-dine1, Abdelhalem Mesfioui1, Aboubaker El-Hessni1
...mine the impact of MD on anxiety- and depression-like behaviors and oxidative stress (OS) in the prefrontal cortex (PFC) of rats across different ages (adolescence, emerging adulthood, and middle adulthood) and the possible existence of sexual dimorphisms. Rat pups were maternally deprived on postnatal day 9 for 24 hours. The rats of both genders were then tested in the open field and the elevated plus-maze tests for anxiety...
Jin Jiao1, Jin Song1, Yuanyuan Cui1, Yilin Wang2, Yanling Li1, Jing Li1, Yan Su1, Xiaojing Du3, Yan Wang3, Guiping Sun3 and Minxiang Wei4*
...ep disturbance, fatigue, anxiety and depression in patients with myocardial infarction (MI) and analyse the relationship between fatigue and sleep disturbance, anxiety and depression. A cross-sectional research method was used to recruit 190 patients who were at least one-week post-MI as the research participants. The Pittsburgh Sleep Quality Index, the Chinese version of the Multidimensional Fatigue Scale and the Hospital <...
Abdelghafour El-Hamzaoui*, Mouloud Lamtai, Laila Ibouzine‑Dine, Sofia Azirar, Mohamed Yassine El-Brouzi, Ayoub Rezqaoui, Aboubaker El-Hessni, Abdelhalem Mesfioui
...re over 8-week period on anxiety- and depression-like behaviors in male Wistar rats, administering daily subcutaneous injections of four different doses 25, 50, 75, and 100 mg/kg of GBH while a control group received 0.9% NaCl. Based on behavioral tests (the open field, elevated cross maze, and forced swim), behavioral alterations were detected, specifically anxiety levels and depressive behavior. Simultaneously, hippocampal...
Laila Ibouzine-Dine1*, Inssaf Berkiks1,2, Hasnaa Mallouk1, Mouloud Lamtai1, Zineb El Marzouki1, Amal Dimaoui1, Abdelhalem Mesfioui1, Aboubaker El Hessni1
...y showed more pronounced anxiety-like and depressive-like behaviors with higher biomarker levels than females. Understanding these sex-specific NO release patterns and how they affect adolescents could be crucial to understanding the neurochemical processes that underlie the development of depression and other mental health disorders.
Keywords | Neonatal, Early-life programming, Sex differences, Wistar rat, Nitric oxide, Central ...
Idrissi Ouedrhiri Housna1, Bikri Samir1,2*, Benloughmari Douae1, Aboussaleh Youssef1
Zhongjiang Niu1, Periyannan Velu2, Annamalai Vijayalakshmi2*
...ing score, hypertension, anxiety, discrimination ability (SNSE), learning, and memory in eight groups of rats. PTZ – kindling rats showed poor motor activity. PTZ-kindling rats showed increase in emotional tension, anxiety, learning and memory, pro-inflammatory mediators (IL-1β and TNF-α) in hippocampal tissue, neuronal damage (increased sNSE), mitochondrial dysfunction, and oxidative stress. PTZ-kindling au...
Eman Wahsh1, Tarek M Ibrahim2, Mirna E. ElAwady3*
...es the physical signs of anxiety by blocking adrenergic neurotransmitters. Currently, Vogel conflict paradigm was applied to measure anxiety and validated by using anxiolytic agent, diazepam, and anxiogenic drug, caffeine. Vogel paradigm is based on the conflict between animal’s licking water and receiving electric shocks. Rats were individually tested in the anxiometer for a 10-min session; the licks/shock ratio was f...
